4YPZA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
248
structure length
236
Chain Sequence
SHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 71
structure length 236
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4ypzA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4ypzA01
4YQQA 4YVGA 3KNUA 4X3LA 1X7PA 5GMBA 1VHKA 3NK7A 4CNDA 5GM8A 3KY7A 4YQPA 4H3YA 1NS5A 1X7OA 4YQIA 4YQ8A 4YQNA 4FAKA 4CNEA 1IPAA 2I6DA 4J3CA 4MCBA 3KW2A 3N4KA 1VHYA 4YQGA 4YPYA 3AI9X 1OY5A 2CX8A 4YQKA 1NXZA 4YQ7A 1MXIA 4RG1A 1K3RA 3O7BA 3KTYA 1J85A 4YVHA 4IG6A 4YQLA 3ONPA 4YQTA 4YQBA 2V3KA 1UAJA 1V2XA 5GMCA 1V6ZA 4YVJA 2QWVA 1TO0A 4YQOA 4YQJA 4YVIA 4H3ZA 4MCCA 1P9PA 4YQ1A 4KDZA 2EGVA 4YPZA 1GZ0A 3E5YA 4PZKA 4YQ5A 4YPXA 3OIIA 4YQ6A 3DCMX 4YQ3A 3IEFA 4L69A 3QUVA 4MCDA 4CNFA 4YQAA 2O3AA 4CNGA 4E8BA 1VH0A 1UAMA 4YQRA 5D9FA 4YQ4A 4YPWA 4JAKA 3GYQA 3AXZA 5CO4A 1ZJRA 4YQ2A 3BBDA 2YY8A 5FAIA 1Z85A 3AIAA 3BBEA 3BBHA 2Z0YA 3L8UA 2HA8A 3NK6A 3OINA 4YVKA 1UAKA 4YQSA 2V3JA 2EGWA 4X3MA 3IC6A 4YQCA 4YQ0A 4YQDA 1O6DA 4KGNA 3OIJA 3ILKA 3N4JA 2QMMA 4XBOA 4YQ9A 1UALA 4JALA
chains in the Genus database with same CATH superfamily
4YQQA 4YVGA 3KNUA 4X3LA 1X7PA 5GMBA 1TRRA 1VHKA 3NK7A 1JHGA 4CNDA 5GM8A 3KY7A 1RCSA 4YQPA 4H3YA 1NS5A 1X7OA 1ZT9A 4YQIA 4YQ8A 4YQNA 4FAKA 4CNEA 1IPAA 2I6DA 4J3CA 4MCBA 3KW2A 3N4KA 4YQGA 1VHYA 3SSWN 4YPYA 3AI9X 1OY5A 2CX8A 4YQKA 1NXZA 4YQ7A 1MXIA 4RG1A 1K3RA 3O7BA 3KTYA 1J85A 4YVHA 4IG6A 4YQLA 3ONPA 4YQTA 4YQBA 1MI7R 3G1CA 2V3KA 1UAJA 4JWFA 1V2XA 4JWHA 2XDIA 1V6ZA 5GMCA 4YVJA 2QWVA 1TO0A 1TROA 4YQOA 4YQJA 4YVIA 4H3ZA 1WRTR 4MCCA 1P9PA 4YQ1A 4KDZA 2EGVA 4YPZA 1GZ0A 3E5YA 2OZ9R 4PZKA 4YQ5A 4YPXA 3OIIA 4YQ6A 3DCMX 4YQ3A 1WRSR 3IEFA 4L69A 4FMWA 3QUVA 1WRPR 4MCDA 4CNFA 4YQAA 2O3AA 4CNGA 4E8BA 1VH0A 1UAMA 4YQRA 5D9FA 4YQ4A 4YPWA 3WRPA 4JAKA 3GYQA 3FRWA 3AXZA 4JWGA 4JWJA 1ZJRA 5CO4A 4YQ2A 3BBDA 2YY8A 5FAIA 1Z85A 3AIAA 3BBEA 3BBHA 2Z0YA 3L8UA 2HA8A 3NK6A 3OINA 4YVKA 1UAKA 4YQSA 1CO0A 2V3JA 2EGWA 4X3MA 3IC6A 4YQCA 4YQ0A 4YQDA 3KORA 1O6DA 4KGNA 3OIJA 3ILKA 3N4JA 2QMMA 3SSXN 4XBOA 4YQ9A 1UALA 4JALA
chains in the Genus database with same CATH topology
4YQQA 4YVGA 3KNUA 4X3LA 1X7PA 5GMBA 1VHKA 3NK7A 4CNDA 5GM8A 3KY7A 4YQPA 4H3YA 1NS5A 1X7OA 4YQIA 4YQ8A 4YQNA 4FAKA 4CNEA 1IPAA 2I6DA 4J3CA 4MCBA 3KW2A 3N4KA 1VHYA 4YQGA 4YPYA 3AI9X 1OY5A 2CX8A 4YQKA 1NXZA 4YQ7A 1MXIA 4RG1A 1K3RA 3O7BA 3KTYA 1J85A 4YVHA 4IG6A 4YQLA 3ONPA 4YQTA 4YQBA 2V3KA 1UAJA 4JWFA 1V2XA 4JWHA 5GMCA 1V6ZA 4YVJA 2QWVA 1TO0A 4YQOA 4YQJA 4YVIA 4H3ZA 4MCCA 1P9PA 4YQ1A 4KDZA 2EGVA 4YPZA 1GZ0A 3E5YA 4PZKA 4YQ5A 4YPXA 3OIIA 4YQ6A 3DCMX 4YQ3A 3IEFA 4L69A 4FMWA 3QUVA 4MCDA 4CNFA 4YQAA 2O3AA 4CNGA 4E8BA 1VH0A 1UAMA 4YQRA 5D9FA 4YQ4A 4YPWA 4JAKA 3GYQA 3AXZA 4JWGA 4JWJA 1ZJRA 5CO4A 4YQ2A 3BBDA 2YY8A 5FAIA 1Z85A 3AIAA 3BBEA 3BBHA 2Z0YA 3L8UA 2HA8A 3NK6A 3OINA 4YVKA 1UAKA 4YQSA 2V3JA 2EGWA 4X3MA 3IC6A 4YQCA 4YQ0A 4YQDA 1O6DA 4KGNA 3OIJA 3ILKA 3N4JA 2QMMA 4XBOA 4YQ9A 1UALA 4JALA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQQ A;  4YVG A;  3KNU A;  4X3L A;  1X7P A;  5GMB A;  1VHK A;  3NK7 A;  4CND A;  5GM8 A;  3KY7 A;  4YQP A;  4H3Y A;  1NS5 A;  1X7O A;  4YQI A;  4YQ8 A;  4YQN A;  4FAK A;  4CNE A;  1IPA A;  2I6D A;  4J3C A;  4MCB A;  3KW2 A;  3N4K A;  1VHY A;  4YQG A;  4YPY A;  3AI9 X;  1OY5 A;  2CX8 A;  4YQK A;  1NXZ A;  4YQ7 A;  1MXI A;  4RG1 A;  1K3R A;  3O7B A;  3KTY A;  1J85 A;  4YVH A;  4IG6 A;  4YQL A;  3ONP A;  4YQT A;  4YQB A;  2V3K A;  1UAJ A;  1V2X A;  5GMC A;  1V6Z A;  4YVJ A;  2QWV A;  1TO0 A;  4YQO A;  4YQJ A;  4YVI A;  4H3Z A;  4MCC A;  1P9P A;  4YQ1 A;  4KDZ A;  2EGV A;  4YPZ A;  1GZ0 A;  3E5Y A;  4PZK A;  4YQ5 A;  4YPX A;  3OII A;  4YQ6 A;  3DCM X;  4YQ3 A;  3IEF A;  4L69 A;  3QUV A;  4MCD A;  4CNF A;  4YQA A;  2O3A A;  4CNG A;  4E8B A;  1VH0 A;  1UAM A;  4YQR A;  5D9F A;  4YQ4 A;  4YPW A;  4JAK A;  3GYQ A;  3AXZ A;  5CO4 A;  1ZJR A;  4YQ2 A;  3BBD A;  2YY8 A;  5FAI A;  1Z85 A;  3AIA A;  3BBE A;  3BBH A;  2Z0Y A;  3L8U A;  2HA8 A;  3NK6 A;  3OIN A;  4YVK A;  1UAK A;  4YQS A;  2V3J A;  2EGW A;  4X3M A;  3IC6 A;  4YQC A;  4YQ0 A;  4YQD A;  1O6D A;  4KGN A;  3OIJ A;  3ILK A;  3N4J A;  2QMM A;  4XBO A;  4YQ9 A;  1UAL A;  4JAL A; 
#chains in the Genus database with same CATH topology
 4YQQ A;  4YVG A;  3KNU A;  4X3L A;  1X7P A;  5GMB A;  1TRR A;  1VHK A;  3NK7 A;  1JHG A;  4CND A;  5GM8 A;  3KY7 A;  1RCS A;  4YQP A;  4H3Y A;  1NS5 A;  1X7O A;  1ZT9 A;  4YQI A;  4YQ8 A;  4YQN A;  4FAK A;  4CNE A;  1IPA A;  2I6D A;  4J3C A;  4MCB A;  3KW2 A;  3N4K A;  4YQG A;  1VHY A;  3SSW N;  4YPY A;  3AI9 X;  1OY5 A;  2CX8 A;  4YQK A;  1NXZ A;  4YQ7 A;  1MXI A;  4RG1 A;  1K3R A;  3O7B A;  3KTY A;  1J85 A;  4YVH A;  4IG6 A;  4YQL A;  3ONP A;  4YQT A;  4YQB A;  1MI7 R;  3G1C A;  2V3K A;  1UAJ A;  4JWF A;  1V2X A;  4JWH A;  2XDI A;  1V6Z A;  5GMC A;  4YVJ A;  2QWV A;  1TO0 A;  1TRO A;  4YQO A;  4YQJ A;  4YVI A;  4H3Z A;  1WRT R;  4MCC A;  1P9P A;  4YQ1 A;  4KDZ A;  2EGV A;  4YPZ A;  1GZ0 A;  3E5Y A;  2OZ9 R;  4PZK A;  4YQ5 A;  4YPX A;  3OII A;  4YQ6 A;  3DCM X;  4YQ3 A;  1WRS R;  3IEF A;  4L69 A;  4FMW A;  3QUV A;  1WRP R;  4MCD A;  4CNF A;  4YQA A;  2O3A A;  4CNG A;  4E8B A;  1VH0 A;  1UAM A;  4YQR A;  5D9F A;  4YQ4 A;  4YPW A;  3WRP A;  4JAK A;  3GYQ A;  3FRW A;  3AXZ A;  4JWG A;  4JWJ A;  1ZJR A;  5CO4 A;  4YQ2 A;  3BBD A;  2YY8 A;  5FAI A;  1Z85 A;  3AIA A;  3BBE A;  3BBH A;  2Z0Y A;  3L8U A;  2HA8 A;  3NK6 A;  3OIN A;  4YVK A;  1UAK A;  4YQS A;  1CO0 A;  2V3J A;  2EGW A;  4X3M A;  3IC6 A;  4YQC A;  4YQ0 A;  4YQD A;  3KOR A;  1O6D A;  4KGN A;  3OIJ A;  3ILK A;  3N4J A;  2QMM A;  3SSX N;  4XBO A;  4YQ9 A;  1UAL A;  4JAL A; 
#chains in the Genus database with same CATH homology
 4YQQ A;  4YVG A;  3KNU A;  4X3L A;  1X7P A;  5GMB A;  1VHK A;  3NK7 A;  4CND A;  5GM8 A;  3KY7 A;  4YQP A;  4H3Y A;  1NS5 A;  1X7O A;  4YQI A;  4YQ8 A;  4YQN A;  4FAK A;  4CNE A;  1IPA A;  2I6D A;  4J3C A;  4MCB A;  3KW2 A;  3N4K A;  1VHY A;  4YQG A;  4YPY A;  3AI9 X;  1OY5 A;  2CX8 A;  4YQK A;  1NXZ A;  4YQ7 A;  1MXI A;  4RG1 A;  1K3R A;  3O7B A;  3KTY A;  1J85 A;  4YVH A;  4IG6 A;  4YQL A;  3ONP A;  4YQT A;  4YQB A;  2V3K A;  1UAJ A;  4JWF A;  1V2X A;  4JWH A;  5GMC A;  1V6Z A;  4YVJ A;  2QWV A;  1TO0 A;  4YQO A;  4YQJ A;  4YVI A;  4H3Z A;  4MCC A;  1P9P A;  4YQ1 A;  4KDZ A;  2EGV A;  4YPZ A;  1GZ0 A;  3E5Y A;  4PZK A;  4YQ5 A;  4YPX A;  3OII A;  4YQ6 A;  3DCM X;  4YQ3 A;  3IEF A;  4L69 A;  4FMW A;  3QUV A;  4MCD A;  4CNF A;  4YQA A;  2O3A A;  4CNG A;  4E8B A;  1VH0 A;  1UAM A;  4YQR A;  5D9F A;  4YQ4 A;  4YPW A;  4JAK A;  3GYQ A;  3AXZ A;  4JWG A;  4JWJ A;  1ZJR A;  5CO4 A;  4YQ2 A;  3BBD A;  2YY8 A;  5FAI A;  1Z85 A;  3AIA A;  3BBE A;  3BBH A;  2Z0Y A;  3L8U A;  2HA8 A;  3NK6 A;  3OIN A;  4YVK A;  1UAK A;  4YQS A;  2V3J A;  2EGW A;  4X3M A;  3IC6 A;  4YQC A;  4YQ0 A;  4YQD A;  1O6D A;  4KGN A;  3OIJ A;  3ILK A;  3N4J A;  2QMM A;  4XBO A;  4YQ9 A;  1UAL A;  4JAL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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