4YQ2A

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 67
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
248
structure length
236
Chain Sequence
RGSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
total genus 67
structure length 236
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yq2A02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yq2A01
4YQAA 2O3AA 1IPAA 3OIJA 4E8BA 1V2XA 4YPZA 4YVHA 5GMBA 2EGVA 4FAKA 2I6DA 4CNDA 4YQ9A 4YQDA 4CNEA 1VHKA 1MXIA 1X7PA 4YQ5A 3AI9X 1UALA 2CX8A 1O6DA 1VH0A 4YQKA 3IEFA 4JALA 3DCMX 1UAKA 4YQ8A 5CO4A 3OINA 2QWVA 4JAKA 4YQSA 1UAJA 3E5YA 3BBHA 4YQNA 4YVGA 1ZJRA 4YQ4A 3KY7A 4MCDA 3AXZA 4YQGA 1NS5A 2YY8A 3N4JA 3ONPA 3QUVA 4H3ZA 4YQ2A 3GYQA 1P9PA 4YQQA 3OIIA 4YVIA 4X3MA 3N4KA 5FAIA 4YVKA 3BBDA 4YQLA 2V3KA 4YQ1A 4YQRA 4YQ3A 3IC6A 4CNFA 1GZ0A 3KNUA 3AIAA 3NK7A 3KW2A 4YPXA 4MCCA 3O7BA 4X3LA 2Z0YA 4L69A 4YQ0A 3ILKA 4H3YA 5D9FA 1K3RA 5GMCA 2QMMA 4KGNA 2HA8A 2EGWA 4RG1A 3BBEA 4YQ6A 1NXZA 4YQ7A 4YQBA 2V3JA 1VHYA 4IG6A 1UAMA 5GM8A 1TO0A 1V6ZA 4YQJA 4KDZA 4PZKA 4YQCA 4J3CA 4YVJA 1J85A 3KTYA 1X7OA 1Z85A 3L8UA 4YQTA 4YPYA 4CNGA 3NK6A 4YQOA 4XBOA 4MCBA 4YPWA 1OY5A 4YQIA 4YQPA
chains in the Genus database with same CATH superfamily
4YQAA 2O3AA 1IPAA 3OIJA 4E8BA 1V2XA 4YPZA 4YVHA 5GMBA 2EGVA 2XDIA 4FAKA 2I6DA 4CNDA 4YQ9A 4YQDA 4CNEA 1VHKA 1MXIA 1X7PA 4YQ5A 3AI9X 1UALA 2CX8A 1O6DA 1VH0A 4YQKA 3IEFA 4JALA 3DCMX 1UAKA 4YQ8A 5CO4A 3OINA 2QWVA 1MI7R 4JAKA 4YQSA 1UAJA 3E5YA 1WRSR 4FMWA 3BBHA 4JWHA 4YQNA 1TRRA 4JWGA 4YVGA 3WRPA 1CO0A 1ZJRA 3SSXN 4YQ4A 3KY7A 4MCDA 3AXZA 4YQGA 1NS5A 2YY8A 1TROA 3N4JA 3ONPA 1ZT9A 3QUVA 4H3ZA 4YQ2A 3GYQA 1P9PA 4YQQA 3G1CA 3OIIA 4YVIA 4X3MA 3N4KA 3KORA 5FAIA 4YVKA 3BBDA 4YQLA 2V3KA 4YQ1A 4YQRA 2OZ9R 4YQ3A 3IC6A 4CNFA 1GZ0A 3KNUA 3AIAA 3NK7A 3KW2A 4YPXA 4MCCA 3O7BA 4X3LA 2Z0YA 4L69A 4YQ0A 3ILKA 4H3YA 5D9FA 1K3RA 5GMCA 1JHGA 2QMMA 4KGNA 2HA8A 2EGWA 4RG1A 3BBEA 4JWFA 4YQ6A 1NXZA 4YQ7A 1WRTR 3FRWA 1WRPR 4YQBA 2V3JA 1VHYA 1UAMA 4IG6A 5GM8A 1TO0A 1V6ZA 4YQJA 4KDZA 4PZKA 4YQCA 4J3CA 4YVJA 3SSWN 1J85A 3KTYA 1X7OA 1Z85A 3L8UA 4YQTA 4JWJA 4YPYA 4CNGA 1RCSA 3NK6A 4YQOA 4XBOA 4MCBA 4YPWA 1OY5A 4YQIA 4YQPA
chains in the Genus database with same CATH topology
4YQAA 2O3AA 1IPAA 3OIJA 4E8BA 1V2XA 4YPZA 4YVHA 5GMBA 2EGVA 4FAKA 2I6DA 4CNDA 4YQ9A 4YQDA 4CNEA 1VHKA 1MXIA 1X7PA 4YQ5A 3AI9X 1UALA 2CX8A 1O6DA 1VH0A 4YQKA 3IEFA 4JALA 3DCMX 1UAKA 4YQ8A 5CO4A 3OINA 2QWVA 4JAKA 4YQSA 1UAJA 3E5YA 4FMWA 3BBHA 4JWHA 4YQNA 4JWGA 4YVGA 1ZJRA 4YQ4A 3KY7A 4MCDA 3AXZA 4YQGA 1NS5A 2YY8A 3N4JA 3ONPA 3QUVA 4H3ZA 4YQ2A 3GYQA 1P9PA 4YQQA 3OIIA 4YVIA 4X3MA 3N4KA 5FAIA 4YVKA 3BBDA 4YQLA 2V3KA 4YQ1A 4YQRA 4YQ3A 3IC6A 4CNFA 1GZ0A 3KNUA 3AIAA 3NK7A 3KW2A 4YPXA 4MCCA 3O7BA 4X3LA 2Z0YA 4L69A 4YQ0A 3ILKA 4H3YA 5D9FA 1K3RA 5GMCA 2QMMA 4KGNA 2HA8A 2EGWA 4RG1A 3BBEA 4JWFA 4YQ6A 1NXZA 4YQ7A 4YQBA 2V3JA 1VHYA 4IG6A 1UAMA 5GM8A 1TO0A 1V6ZA 4YQJA 4KDZA 4PZKA 4YQCA 4J3CA 4YVJA 1J85A 3KTYA 1X7OA 1Z85A 3L8UA 4YQTA 4JWJA 4YPYA 4CNGA 3NK6A 4YQOA 4XBOA 4MCBA 4YPWA 1OY5A 4YQIA 4YQPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQA A;  2O3A A;  1IPA A;  3OIJ A;  4E8B A;  1V2X A;  4YPZ A;  4YVH A;  5GMB A;  2EGV A;  4FAK A;  2I6D A;  4CND A;  4YQ9 A;  4YQD A;  4CNE A;  1VHK A;  1MXI A;  1X7P A;  4YQ5 A;  3AI9 X;  1UAL A;  2CX8 A;  1O6D A;  1VH0 A;  4YQK A;  3IEF A;  4JAL A;  3DCM X;  1UAK A;  4YQ8 A;  5CO4 A;  3OIN A;  2QWV A;  4JAK A;  4YQS A;  1UAJ A;  3E5Y A;  3BBH A;  4YQN A;  4YVG A;  1ZJR A;  4YQ4 A;  3KY7 A;  4MCD A;  3AXZ A;  4YQG A;  1NS5 A;  2YY8 A;  3N4J A;  3ONP A;  3QUV A;  4H3Z A;  4YQ2 A;  3GYQ A;  1P9P A;  4YQQ A;  3OII A;  4YVI A;  4X3M A;  3N4K A;  5FAI A;  4YVK A;  3BBD A;  4YQL A;  2V3K A;  4YQ1 A;  4YQR A;  4YQ3 A;  3IC6 A;  4CNF A;  1GZ0 A;  3KNU A;  3AIA A;  3NK7 A;  3KW2 A;  4YPX A;  4MCC A;  3O7B A;  4X3L A;  2Z0Y A;  4L69 A;  4YQ0 A;  3ILK A;  4H3Y A;  5D9F A;  1K3R A;  5GMC A;  2QMM A;  4KGN A;  2HA8 A;  2EGW A;  4RG1 A;  3BBE A;  4YQ6 A;  1NXZ A;  4YQ7 A;  4YQB A;  2V3J A;  1VHY A;  4IG6 A;  1UAM A;  5GM8 A;  1TO0 A;  1V6Z A;  4YQJ A;  4KDZ A;  4PZK A;  4YQC A;  4J3C A;  4YVJ A;  1J85 A;  3KTY A;  1X7O A;  1Z85 A;  3L8U A;  4YQT A;  4YPY A;  4CNG A;  3NK6 A;  4YQO A;  4XBO A;  4MCB A;  4YPW A;  1OY5 A;  4YQI A;  4YQP A; 
#chains in the Genus database with same CATH topology
 4YQA A;  2O3A A;  1IPA A;  3OIJ A;  4E8B A;  1V2X A;  4YPZ A;  4YVH A;  5GMB A;  2EGV A;  2XDI A;  4FAK A;  2I6D A;  4CND A;  4YQ9 A;  4YQD A;  4CNE A;  1VHK A;  1MXI A;  1X7P A;  4YQ5 A;  3AI9 X;  1UAL A;  2CX8 A;  1O6D A;  1VH0 A;  4YQK A;  3IEF A;  4JAL A;  3DCM X;  1UAK A;  4YQ8 A;  5CO4 A;  3OIN A;  2QWV A;  1MI7 R;  4JAK A;  4YQS A;  1UAJ A;  3E5Y A;  1WRS R;  4FMW A;  3BBH A;  4JWH A;  4YQN A;  1TRR A;  4JWG A;  4YVG A;  3WRP A;  1CO0 A;  1ZJR A;  3SSX N;  4YQ4 A;  3KY7 A;  4MCD A;  3AXZ A;  4YQG A;  1NS5 A;  2YY8 A;  1TRO A;  3N4J A;  3ONP A;  1ZT9 A;  3QUV A;  4H3Z A;  4YQ2 A;  3GYQ A;  1P9P A;  4YQQ A;  3G1C A;  3OII A;  4YVI A;  4X3M A;  3N4K A;  3KOR A;  5FAI A;  4YVK A;  3BBD A;  4YQL A;  2V3K A;  4YQ1 A;  4YQR A;  2OZ9 R;  4YQ3 A;  3IC6 A;  4CNF A;  1GZ0 A;  3KNU A;  3AIA A;  3NK7 A;  3KW2 A;  4YPX A;  4MCC A;  3O7B A;  4X3L A;  2Z0Y A;  4L69 A;  4YQ0 A;  3ILK A;  4H3Y A;  5D9F A;  1K3R A;  5GMC A;  1JHG A;  2QMM A;  4KGN A;  2HA8 A;  2EGW A;  4RG1 A;  3BBE A;  4JWF A;  4YQ6 A;  1NXZ A;  4YQ7 A;  1WRT R;  3FRW A;  1WRP R;  4YQB A;  2V3J A;  1VHY A;  1UAM A;  4IG6 A;  5GM8 A;  1TO0 A;  1V6Z A;  4YQJ A;  4KDZ A;  4PZK A;  4YQC A;  4J3C A;  4YVJ A;  3SSW N;  1J85 A;  3KTY A;  1X7O A;  1Z85 A;  3L8U A;  4YQT A;  4JWJ A;  4YPY A;  4CNG A;  1RCS A;  3NK6 A;  4YQO A;  4XBO A;  4MCB A;  4YPW A;  1OY5 A;  4YQI A;  4YQP A; 
#chains in the Genus database with same CATH homology
 4YQA A;  2O3A A;  1IPA A;  3OIJ A;  4E8B A;  1V2X A;  4YPZ A;  4YVH A;  5GMB A;  2EGV A;  4FAK A;  2I6D A;  4CND A;  4YQ9 A;  4YQD A;  4CNE A;  1VHK A;  1MXI A;  1X7P A;  4YQ5 A;  3AI9 X;  1UAL A;  2CX8 A;  1O6D A;  1VH0 A;  4YQK A;  3IEF A;  4JAL A;  3DCM X;  1UAK A;  4YQ8 A;  5CO4 A;  3OIN A;  2QWV A;  4JAK A;  4YQS A;  1UAJ A;  3E5Y A;  4FMW A;  3BBH A;  4JWH A;  4YQN A;  4JWG A;  4YVG A;  1ZJR A;  4YQ4 A;  3KY7 A;  4MCD A;  3AXZ A;  4YQG A;  1NS5 A;  2YY8 A;  3N4J A;  3ONP A;  3QUV A;  4H3Z A;  4YQ2 A;  3GYQ A;  1P9P A;  4YQQ A;  3OII A;  4YVI A;  4X3M A;  3N4K A;  5FAI A;  4YVK A;  3BBD A;  4YQL A;  2V3K A;  4YQ1 A;  4YQR A;  4YQ3 A;  3IC6 A;  4CNF A;  1GZ0 A;  3KNU A;  3AIA A;  3NK7 A;  3KW2 A;  4YPX A;  4MCC A;  3O7B A;  4X3L A;  2Z0Y A;  4L69 A;  4YQ0 A;  3ILK A;  4H3Y A;  5D9F A;  1K3R A;  5GMC A;  2QMM A;  4KGN A;  2HA8 A;  2EGW A;  4RG1 A;  3BBE A;  4JWF A;  4YQ6 A;  1NXZ A;  4YQ7 A;  4YQB A;  2V3J A;  1VHY A;  4IG6 A;  1UAM A;  5GM8 A;  1TO0 A;  1V6Z A;  4YQJ A;  4KDZ A;  4PZK A;  4YQC A;  4J3C A;  4YVJ A;  1J85 A;  3KTY A;  1X7O A;  1Z85 A;  3L8U A;  4YQT A;  4JWJ A;  4YPY A;  4CNG A;  3NK6 A;  4YQO A;  4XBO A;  4MCB A;  4YPW A;  1OY5 A;  4YQI A;  4YQP A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...