4YQ7A

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
249
structure length
238
Chain Sequence
GSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
total genus 73
structure length 238
sequence length 249
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yq7A02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yq7A01
3QUVA 4YQ0A 1MXIA 2EGVA 3KTYA 1VHKA 4CNFA 4YVIA 3NK7A 4RG1A 1X7OA 2V3JA 4YQBA 3O7BA 4YQJA 4L69A 3KNUA 3GYQA 5GMBA 4YQQA 4CNGA 1OY5A 3KY7A 3NK6A 3ONPA 1NXZA 1VHYA 4JAKA 4YQAA 5D9FA 4YVGA 4PZKA 3BBDA 2CX8A 2QMMA 2EGWA 3OIIA 3DCMX 1VH0A 4YQIA 4E8BA 4YQ9A 3KW2A 5FAIA 1J85A 1ZJRA 4YQNA 3BBEA 5CO4A 4YQPA 4YPZA 4YQ6A 4YQTA 3IC6A 4MCDA 4MCBA 3N4JA 4MCCA 1K3RA 3AXZA 4YQSA 4CNDA 4YQCA 3BBHA 3AIAA 4IG6A 1NS5A 4KGNA 3AI9X 1UAMA 4YQLA 4YVKA 2QWVA 1TO0A 4J3CA 2Z0YA 1UALA 1O6DA 3N4KA 4YVHA 1IPAA 4YQ4A 3OIJA 1X7PA 4X3MA 4YQ2A 4YPXA 1P9PA 4YQOA 4YQ1A 3L8UA 4JALA 4YQDA 1UAKA 2I6DA 4YQ8A 4YQKA 4KDZA 1GZ0A 4YPYA 4YQ7A 4YQGA 4X3LA 1V2XA 5GMCA 4YPWA 2O3AA 3ILKA 4CNEA 4YVJA 2V3KA 5GM8A 2HA8A 4XBOA 4H3YA 3OINA 4YQ5A 4YQ3A 3IEFA 3E5YA 2YY8A 1UAJA 4FAKA 4H3ZA 4YQRA 1Z85A 1V6ZA
chains in the Genus database with same CATH superfamily
3QUVA 4YQ0A 1MXIA 2EGVA 3KTYA 1VHKA 4CNFA 4YVIA 3NK7A 4RG1A 1X7OA 2V3JA 4YQBA 3O7BA 3SSXN 4YQJA 4L69A 3KNUA 3GYQA 5GMBA 4YQQA 4CNGA 1OY5A 3FRWA 3KY7A 3NK6A 1NXZA 3ONPA 1VHYA 4JAKA 1JHGA 4YQAA 4JWHA 5D9FA 1CO0A 4YVGA 1WRSR 4PZKA 3BBDA 2CX8A 2QMMA 4JWJA 2EGWA 3OIIA 3DCMX 1VH0A 4YQIA 4E8BA 4YQ9A 3KW2A 5FAIA 1J85A 1ZJRA 4YQNA 3BBEA 5CO4A 4YQPA 4YPZA 4YQ6A 4YQTA 3IC6A 4MCDA 4MCBA 1Z85A 3N4JA 4MCCA 1K3RA 3AXZA 4YQSA 4CNDA 4YQCA 3BBHA 3WRPA 4FMWA 3AIAA 4IG6A 4JWFA 1NS5A 4KGNA 3AI9X 4YQLA 3KORA 4YVKA 2QWVA 1TO0A 4J3CA 2Z0YA 1UALA 1O6DA 3N4KA 4YVHA 1WRTR 1IPAA 4YQ4A 3OIJA 1MI7R 1X7PA 4X3MA 3G1CA 4YPXA 1P9PA 4YQOA 4YQ2A 4YQ1A 3L8UA 4JALA 4YQDA 1UAKA 1V6ZA 2I6DA 4YQ8A 4YQKA 4KDZA 1GZ0A 4YPYA 4YQ7A 4YQGA 4X3LA 1V2XA 5GMCA 1RCSA 4YPWA 3SSWN 2O3AA 1TRRA 3ILKA 4CNEA 4YVJA 2V3KA 5GM8A 2HA8A 4XBOA 4H3YA 3OINA 4YQ5A 4YQ3A 3IEFA 1WRPR 3E5YA 2YY8A 1UAJA 2XDIA 4FAKA 4JWGA 1ZT9A 4H3ZA 4YQRA 2OZ9R 1TROA 1UAMA
chains in the Genus database with same CATH topology
3QUVA 4YQ0A 1MXIA 2EGVA 3KTYA 1VHKA 4CNFA 4YVIA 3NK7A 4RG1A 1X7OA 2V3JA 4YQBA 3O7BA 4YQJA 4L69A 3KNUA 3GYQA 5GMBA 4YQQA 4CNGA 1OY5A 3KY7A 3NK6A 3ONPA 1NXZA 1VHYA 4JAKA 4YQAA 4JWHA 5D9FA 4YVGA 4PZKA 3BBDA 2CX8A 2QMMA 4JWJA 2EGWA 3OIIA 3DCMX 1VH0A 4YQIA 4E8BA 4YQ9A 3KW2A 5FAIA 1J85A 1ZJRA 4YQNA 3BBEA 5CO4A 4YQPA 4YPZA 4YQ6A 4YQTA 3IC6A 4MCDA 4MCBA 3N4JA 4MCCA 1K3RA 3AXZA 4YQSA 4CNDA 4YQCA 3BBHA 4FMWA 3AIAA 4IG6A 4JWFA 1NS5A 4KGNA 3AI9X 1UAMA 4YQLA 4YVKA 2QWVA 1TO0A 4J3CA 2Z0YA 1UALA 1O6DA 3N4KA 4YVHA 1IPAA 4YQ4A 3OIJA 1X7PA 4X3MA 4YQ2A 4YPXA 1P9PA 4YQOA 4YQ1A 3L8UA 4JALA 4YQDA 1UAKA 2I6DA 4YQ8A 4YQKA 4KDZA 1GZ0A 4YPYA 4YQ7A 4YQGA 4X3LA 1V2XA 5GMCA 4YPWA 2O3AA 3ILKA 4CNEA 4YVJA 2V3KA 5GM8A 2HA8A 4XBOA 4H3YA 3OINA 4YQ5A 4YQ3A 3IEFA 3E5YA 2YY8A 1UAJA 4FAKA 4JWGA 4H3ZA 4YQRA 1Z85A 1V6ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QUV A;  4YQ0 A;  1MXI A;  2EGV A;  3KTY A;  1VHK A;  4CNF A;  4YVI A;  3NK7 A;  4RG1 A;  1X7O A;  2V3J A;  4YQB A;  3O7B A;  4YQJ A;  4L69 A;  3KNU A;  3GYQ A;  5GMB A;  4YQQ A;  4CNG A;  1OY5 A;  3KY7 A;  3NK6 A;  3ONP A;  1NXZ A;  1VHY A;  4JAK A;  4YQA A;  5D9F A;  4YVG A;  4PZK A;  3BBD A;  2CX8 A;  2QMM A;  2EGW A;  3OII A;  3DCM X;  1VH0 A;  4YQI A;  4E8B A;  4YQ9 A;  3KW2 A;  5FAI A;  1J85 A;  1ZJR A;  4YQN A;  3BBE A;  5CO4 A;  4YQP A;  4YPZ A;  4YQ6 A;  4YQT A;  3IC6 A;  4MCD A;  4MCB A;  3N4J A;  4MCC A;  1K3R A;  3AXZ A;  4YQS A;  4CND A;  4YQC A;  3BBH A;  3AIA A;  4IG6 A;  1NS5 A;  4KGN A;  3AI9 X;  1UAM A;  4YQL A;  4YVK A;  2QWV A;  1TO0 A;  4J3C A;  2Z0Y A;  1UAL A;  1O6D A;  3N4K A;  4YVH A;  1IPA A;  4YQ4 A;  3OIJ A;  1X7P A;  4X3M A;  4YQ2 A;  4YPX A;  1P9P A;  4YQO A;  4YQ1 A;  3L8U A;  4JAL A;  4YQD A;  1UAK A;  2I6D A;  4YQ8 A;  4YQK A;  4KDZ A;  1GZ0 A;  4YPY A;  4YQ7 A;  4YQG A;  4X3L A;  1V2X A;  5GMC A;  4YPW A;  2O3A A;  3ILK A;  4CNE A;  4YVJ A;  2V3K A;  5GM8 A;  2HA8 A;  4XBO A;  4H3Y A;  3OIN A;  4YQ5 A;  4YQ3 A;  3IEF A;  3E5Y A;  2YY8 A;  1UAJ A;  4FAK A;  4H3Z A;  4YQR A;  1Z85 A;  1V6Z A; 
#chains in the Genus database with same CATH topology
 3QUV A;  4YQ0 A;  1MXI A;  2EGV A;  3KTY A;  1VHK A;  4CNF A;  4YVI A;  3NK7 A;  4RG1 A;  1X7O A;  2V3J A;  4YQB A;  3O7B A;  3SSX N;  4YQJ A;  4L69 A;  3KNU A;  3GYQ A;  5GMB A;  4YQQ A;  4CNG A;  1OY5 A;  3FRW A;  3KY7 A;  3NK6 A;  1NXZ A;  3ONP A;  1VHY A;  4JAK A;  1JHG A;  4YQA A;  4JWH A;  5D9F A;  1CO0 A;  4YVG A;  1WRS R;  4PZK A;  3BBD A;  2CX8 A;  2QMM A;  4JWJ A;  2EGW A;  3OII A;  3DCM X;  1VH0 A;  4YQI A;  4E8B A;  4YQ9 A;  3KW2 A;  5FAI A;  1J85 A;  1ZJR A;  4YQN A;  3BBE A;  5CO4 A;  4YQP A;  4YPZ A;  4YQ6 A;  4YQT A;  3IC6 A;  4MCD A;  4MCB A;  1Z85 A;  3N4J A;  4MCC A;  1K3R A;  3AXZ A;  4YQS A;  4CND A;  4YQC A;  3BBH A;  3WRP A;  4FMW A;  3AIA A;  4IG6 A;  4JWF A;  1NS5 A;  4KGN A;  3AI9 X;  4YQL A;  3KOR A;  4YVK A;  2QWV A;  1TO0 A;  4J3C A;  2Z0Y A;  1UAL A;  1O6D A;  3N4K A;  4YVH A;  1WRT R;  1IPA A;  4YQ4 A;  3OIJ A;  1MI7 R;  1X7P A;  4X3M A;  3G1C A;  4YPX A;  1P9P A;  4YQO A;  4YQ2 A;  4YQ1 A;  3L8U A;  4JAL A;  4YQD A;  1UAK A;  1V6Z A;  2I6D A;  4YQ8 A;  4YQK A;  4KDZ A;  1GZ0 A;  4YPY A;  4YQ7 A;  4YQG A;  4X3L A;  1V2X A;  5GMC A;  1RCS A;  4YPW A;  3SSW N;  2O3A A;  1TRR A;  3ILK A;  4CNE A;  4YVJ A;  2V3K A;  5GM8 A;  2HA8 A;  4XBO A;  4H3Y A;  3OIN A;  4YQ5 A;  4YQ3 A;  3IEF A;  1WRP R;  3E5Y A;  2YY8 A;  1UAJ A;  2XDI A;  4FAK A;  4JWG A;  1ZT9 A;  4H3Z A;  4YQR A;  2OZ9 R;  1TRO A;  1UAM A; 
#chains in the Genus database with same CATH homology
 3QUV A;  4YQ0 A;  1MXI A;  2EGV A;  3KTY A;  1VHK A;  4CNF A;  4YVI A;  3NK7 A;  4RG1 A;  1X7O A;  2V3J A;  4YQB A;  3O7B A;  4YQJ A;  4L69 A;  3KNU A;  3GYQ A;  5GMB A;  4YQQ A;  4CNG A;  1OY5 A;  3KY7 A;  3NK6 A;  3ONP A;  1NXZ A;  1VHY A;  4JAK A;  4YQA A;  4JWH A;  5D9F A;  4YVG A;  4PZK A;  3BBD A;  2CX8 A;  2QMM A;  4JWJ A;  2EGW A;  3OII A;  3DCM X;  1VH0 A;  4YQI A;  4E8B A;  4YQ9 A;  3KW2 A;  5FAI A;  1J85 A;  1ZJR A;  4YQN A;  3BBE A;  5CO4 A;  4YQP A;  4YPZ A;  4YQ6 A;  4YQT A;  3IC6 A;  4MCD A;  4MCB A;  3N4J A;  4MCC A;  1K3R A;  3AXZ A;  4YQS A;  4CND A;  4YQC A;  3BBH A;  4FMW A;  3AIA A;  4IG6 A;  4JWF A;  1NS5 A;  4KGN A;  3AI9 X;  1UAM A;  4YQL A;  4YVK A;  2QWV A;  1TO0 A;  4J3C A;  2Z0Y A;  1UAL A;  1O6D A;  3N4K A;  4YVH A;  1IPA A;  4YQ4 A;  3OIJ A;  1X7P A;  4X3M A;  4YQ2 A;  4YPX A;  1P9P A;  4YQO A;  4YQ1 A;  3L8U A;  4JAL A;  4YQD A;  1UAK A;  2I6D A;  4YQ8 A;  4YQK A;  4KDZ A;  1GZ0 A;  4YPY A;  4YQ7 A;  4YQG A;  4X3L A;  1V2X A;  5GMC A;  4YPW A;  2O3A A;  3ILK A;  4CNE A;  4YVJ A;  2V3K A;  5GM8 A;  2HA8 A;  4XBO A;  4H3Y A;  3OIN A;  4YQ5 A;  4YQ3 A;  3IEF A;  3E5Y A;  2YY8 A;  1UAJ A;  4FAK A;  4JWG A;  4H3Z A;  4YQR A;  1Z85 A;  1V6Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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