4YQ8A

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
248
structure length
240
Chain Sequence
SHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 70
structure length 240
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yq8A02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yq8A01
4YVJA 5GMCA 3ILKA 1UAMA 4YVGA 4E8BA 3IEFA 4YQ2A 3KTYA 3ONPA 3DCMX 3OIJA 4YQ9A 4YQLA 4MCCA 1NXZA 1NS5A 2V3KA 3OINA 4YQ8A 4YVHA 3O7BA 5GMBA 4PZKA 2EGWA 4YPWA 4YQGA 4KDZA 1UAKA 4YPXA 3QUVA 1X7OA 3BBDA 4X3MA 3NK6A 2O3AA 4YQ1A 1Z85A 4RG1A 4YPZA 2HA8A 4FAKA 4YVIA 3IC6A 1UAJA 4YQ6A 4YQ3A 4YQOA 3AXZA 4YQQA 4CNDA 4YQAA 4YQNA 4H3YA 2EGVA 1OY5A 4CNFA 1ZJRA 3GYQA 4CNEA 4YVKA 2CX8A 2YY8A 2Z0YA 4MCBA 4YQTA 4KGNA 4YQCA 4YQSA 3N4KA 4H3ZA 4X3LA 3AIAA 3NK7A 3KW2A 1TO0A 1UALA 2QMMA 1GZ0A 1IPAA 4XBOA 4YQ7A 4CNGA 4YQBA 4YQPA 1P9PA 1MXIA 4YQDA 2V3JA 3E5YA 5CO4A 1O6DA 4MCDA 3AI9X 4YPYA 5GM8A 4YQ5A 4JAKA 4JALA 5D9FA 2QWVA 3N4JA 4J3CA 4YQIA 1VHKA 1V6ZA 4YQ4A 4IG6A 1V2XA 1VH0A 3BBEA 4L69A 3BBHA 5FAIA 3L8UA 3KY7A 4YQRA 3KNUA 4YQKA 1K3RA 1VHYA 3OIIA 1X7PA 2I6DA 1J85A 4YQ0A 4YQJA
chains in the Genus database with same CATH superfamily
4YVJA 5GMCA 4JWHA 3ILKA 1UAMA 4YVGA 2XDIA 4E8BA 3IEFA 4YQ2A 3G1CA 3KTYA 3ONPA 3DCMX 3OIJA 4YQ9A 4YQLA 4MCCA 1TRRA 1NS5A 1JHGA 1NXZA 2V3KA 3OINA 4YQ8A 4YVHA 3O7BA 5GMBA 4PZKA 2EGWA 4YPWA 1CO0A 4YQGA 4KDZA 1UAKA 4YPXA 3QUVA 1X7OA 3BBDA 4X3MA 3NK6A 2O3AA 4YQ1A 1Z85A 4RG1A 4YPZA 2HA8A 4FAKA 4YVIA 3IC6A 1RCSA 1UAJA 4YQ6A 4YQ3A 1WRSR 3AXZA 4YQOA 4YQQA 4CNDA 4YQAA 4YQNA 4H3YA 4JWFA 2EGVA 2I6DA 1OY5A 4CNFA 1ZT9A 1ZJRA 3GYQA 4CNEA 4YVKA 2CX8A 2YY8A 2Z0YA 4MCBA 4YQTA 3SSWN 4JWJA 3SSXN 4KGNA 4YQCA 4YQSA 3N4KA 4H3ZA 4X3LA 3AIAA 3NK7A 3KW2A 1TO0A 1UALA 1TROA 4FMWA 3WRPA 2QMMA 1GZ0A 1IPAA 4XBOA 4YQ7A 4CNGA 4YQBA 3FRWA 4YQPA 1P9PA 1MXIA 4YQDA 2V3JA 3E5YA 5CO4A 3KORA 1O6DA 4MCDA 3AI9X 4YPYA 5GM8A 2OZ9R 4YQ5A 4JAKA 4JALA 5D9FA 2QWVA 3N4JA 4J3CA 1WRTR 1VHKA 1MI7R 1V6ZA 4YQ4A 1WRPR 4IG6A 1V2XA 1VH0A 3BBEA 4L69A 3BBHA 4JWGA 3L8UA 5FAIA 3KY7A 4YQRA 3KNUA 4YQKA 1K3RA 1VHYA 3OIIA 1X7PA 4YQIA 1J85A 4YQ0A 4YQJA
chains in the Genus database with same CATH topology
4YVJA 5GMCA 4JWHA 3ILKA 1UAMA 4YVGA 4E8BA 3IEFA 4YQ2A 3KTYA 3ONPA 3DCMX 3OIJA 4YQ9A 4YQLA 4MCCA 1NXZA 1NS5A 2V3KA 3OINA 4YQ8A 4YVHA 3O7BA 5GMBA 4PZKA 2EGWA 4YPWA 4YQGA 4KDZA 1UAKA 4YPXA 3QUVA 1X7OA 3BBDA 4X3MA 3NK6A 2O3AA 4YQ1A 1Z85A 4RG1A 4YPZA 2HA8A 4FAKA 4YVIA 3IC6A 1UAJA 4YQ6A 4YQ3A 4YQOA 3AXZA 4YQQA 4CNDA 4YQAA 4YQNA 4H3YA 4JWFA 2EGVA 1OY5A 4CNFA 1ZJRA 3GYQA 4CNEA 4YVKA 2CX8A 2YY8A 2Z0YA 4MCBA 4YQTA 4JWJA 4KGNA 4YQCA 4YQSA 3N4KA 4H3ZA 4X3LA 3AIAA 3NK7A 3KW2A 1TO0A 1UALA 4FMWA 2QMMA 1GZ0A 1IPAA 4XBOA 4YQ7A 4CNGA 4YQBA 4YQPA 1P9PA 1MXIA 4YQDA 2V3JA 3E5YA 5CO4A 1O6DA 4MCDA 3AI9X 4YPYA 5GM8A 4YQ5A 4JAKA 4JALA 5D9FA 2QWVA 3N4JA 4J3CA 4YQIA 1VHKA 1V6ZA 4YQ4A 4IG6A 1V2XA 1VH0A 3BBEA 4L69A 3BBHA 4JWGA 3L8UA 5FAIA 3KY7A 4YQRA 3KNUA 4YQKA 1K3RA 1VHYA 3OIIA 1X7PA 2I6DA 1J85A 4YQ0A 4YQJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YVJ A;  5GMC A;  3ILK A;  1UAM A;  4YVG A;  4E8B A;  3IEF A;  4YQ2 A;  3KTY A;  3ONP A;  3DCM X;  3OIJ A;  4YQ9 A;  4YQL A;  4MCC A;  1NXZ A;  1NS5 A;  2V3K A;  3OIN A;  4YQ8 A;  4YVH A;  3O7B A;  5GMB A;  4PZK A;  2EGW A;  4YPW A;  4YQG A;  4KDZ A;  1UAK A;  4YPX A;  3QUV A;  1X7O A;  3BBD A;  4X3M A;  3NK6 A;  2O3A A;  4YQ1 A;  1Z85 A;  4RG1 A;  4YPZ A;  2HA8 A;  4FAK A;  4YVI A;  3IC6 A;  1UAJ A;  4YQ6 A;  4YQ3 A;  4YQO A;  3AXZ A;  4YQQ A;  4CND A;  4YQA A;  4YQN A;  4H3Y A;  2EGV A;  1OY5 A;  4CNF A;  1ZJR A;  3GYQ A;  4CNE A;  4YVK A;  2CX8 A;  2YY8 A;  2Z0Y A;  4MCB A;  4YQT A;  4KGN A;  4YQC A;  4YQS A;  3N4K A;  4H3Z A;  4X3L A;  3AIA A;  3NK7 A;  3KW2 A;  1TO0 A;  1UAL A;  2QMM A;  1GZ0 A;  1IPA A;  4XBO A;  4YQ7 A;  4CNG A;  4YQB A;  4YQP A;  1P9P A;  1MXI A;  4YQD A;  2V3J A;  3E5Y A;  5CO4 A;  1O6D A;  4MCD A;  3AI9 X;  4YPY A;  5GM8 A;  4YQ5 A;  4JAK A;  4JAL A;  5D9F A;  2QWV A;  3N4J A;  4J3C A;  4YQI A;  1VHK A;  1V6Z A;  4YQ4 A;  4IG6 A;  1V2X A;  1VH0 A;  3BBE A;  4L69 A;  3BBH A;  5FAI A;  3L8U A;  3KY7 A;  4YQR A;  3KNU A;  4YQK A;  1K3R A;  1VHY A;  3OII A;  1X7P A;  2I6D A;  1J85 A;  4YQ0 A;  4YQJ A; 
#chains in the Genus database with same CATH topology
 4YVJ A;  5GMC A;  4JWH A;  3ILK A;  1UAM A;  4YVG A;  2XDI A;  4E8B A;  3IEF A;  4YQ2 A;  3G1C A;  3KTY A;  3ONP A;  3DCM X;  3OIJ A;  4YQ9 A;  4YQL A;  4MCC A;  1TRR A;  1NS5 A;  1JHG A;  1NXZ A;  2V3K A;  3OIN A;  4YQ8 A;  4YVH A;  3O7B A;  5GMB A;  4PZK A;  2EGW A;  4YPW A;  1CO0 A;  4YQG A;  4KDZ A;  1UAK A;  4YPX A;  3QUV A;  1X7O A;  3BBD A;  4X3M A;  3NK6 A;  2O3A A;  4YQ1 A;  1Z85 A;  4RG1 A;  4YPZ A;  2HA8 A;  4FAK A;  4YVI A;  3IC6 A;  1RCS A;  1UAJ A;  4YQ6 A;  4YQ3 A;  1WRS R;  3AXZ A;  4YQO A;  4YQQ A;  4CND A;  4YQA A;  4YQN A;  4H3Y A;  4JWF A;  2EGV A;  2I6D A;  1OY5 A;  4CNF A;  1ZT9 A;  1ZJR A;  3GYQ A;  4CNE A;  4YVK A;  2CX8 A;  2YY8 A;  2Z0Y A;  4MCB A;  4YQT A;  3SSW N;  4JWJ A;  3SSX N;  4KGN A;  4YQC A;  4YQS A;  3N4K A;  4H3Z A;  4X3L A;  3AIA A;  3NK7 A;  3KW2 A;  1TO0 A;  1UAL A;  1TRO A;  4FMW A;  3WRP A;  2QMM A;  1GZ0 A;  1IPA A;  4XBO A;  4YQ7 A;  4CNG A;  4YQB A;  3FRW A;  4YQP A;  1P9P A;  1MXI A;  4YQD A;  2V3J A;  3E5Y A;  5CO4 A;  3KOR A;  1O6D A;  4MCD A;  3AI9 X;  4YPY A;  5GM8 A;  2OZ9 R;  4YQ5 A;  4JAK A;  4JAL A;  5D9F A;  2QWV A;  3N4J A;  4J3C A;  1WRT R;  1VHK A;  1MI7 R;  1V6Z A;  4YQ4 A;  1WRP R;  4IG6 A;  1V2X A;  1VH0 A;  3BBE A;  4L69 A;  3BBH A;  4JWG A;  3L8U A;  5FAI A;  3KY7 A;  4YQR A;  3KNU A;  4YQK A;  1K3R A;  1VHY A;  3OII A;  1X7P A;  4YQI A;  1J85 A;  4YQ0 A;  4YQJ A; 
#chains in the Genus database with same CATH homology
 4YVJ A;  5GMC A;  4JWH A;  3ILK A;  1UAM A;  4YVG A;  4E8B A;  3IEF A;  4YQ2 A;  3KTY A;  3ONP A;  3DCM X;  3OIJ A;  4YQ9 A;  4YQL A;  4MCC A;  1NXZ A;  1NS5 A;  2V3K A;  3OIN A;  4YQ8 A;  4YVH A;  3O7B A;  5GMB A;  4PZK A;  2EGW A;  4YPW A;  4YQG A;  4KDZ A;  1UAK A;  4YPX A;  3QUV A;  1X7O A;  3BBD A;  4X3M A;  3NK6 A;  2O3A A;  4YQ1 A;  1Z85 A;  4RG1 A;  4YPZ A;  2HA8 A;  4FAK A;  4YVI A;  3IC6 A;  1UAJ A;  4YQ6 A;  4YQ3 A;  4YQO A;  3AXZ A;  4YQQ A;  4CND A;  4YQA A;  4YQN A;  4H3Y A;  4JWF A;  2EGV A;  1OY5 A;  4CNF A;  1ZJR A;  3GYQ A;  4CNE A;  4YVK A;  2CX8 A;  2YY8 A;  2Z0Y A;  4MCB A;  4YQT A;  4JWJ A;  4KGN A;  4YQC A;  4YQS A;  3N4K A;  4H3Z A;  4X3L A;  3AIA A;  3NK7 A;  3KW2 A;  1TO0 A;  1UAL A;  4FMW A;  2QMM A;  1GZ0 A;  1IPA A;  4XBO A;  4YQ7 A;  4CNG A;  4YQB A;  4YQP A;  1P9P A;  1MXI A;  4YQD A;  2V3J A;  3E5Y A;  5CO4 A;  1O6D A;  4MCD A;  3AI9 X;  4YPY A;  5GM8 A;  4YQ5 A;  4JAK A;  4JAL A;  5D9F A;  2QWV A;  3N4J A;  4J3C A;  4YQI A;  1VHK A;  1V6Z A;  4YQ4 A;  4IG6 A;  1V2X A;  1VH0 A;  3BBE A;  4L69 A;  3BBH A;  4JWG A;  3L8U A;  5FAI A;  3KY7 A;  4YQR A;  3KNU A;  4YQK A;  1K3R A;  1VHY A;  3OII A;  1X7P A;  2I6D A;  1J85 A;  4YQ0 A;  4YQJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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