4YSZD

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with 2-iodo-n-[3-(1-methylethoxy)phenyl]benzamide
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
129
structure length
129
Chain Sequence
TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase flavoprotein
total genus 40
structure length 129
sequence length 129
chains with identical sequence H
ec nomenclature
pdb deposition date 2015-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05328 CybS CybS, succinate dehydrogenase cytochrome B small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 4yszD00
1NEND 3AEDC 4YT0C 3AE8D 4YTPC 4YSZD 2WDQD 3AEEC 3CIRC 4YTMC 3AEGC 2ACZC 3AEBC 2B76C 3AEFC 3P4PC 3VR8D 3VRAC 3AE5C 3AEAC 4KX6D 1YQ3C 4YXDC 3AE7C 1QLBC 4YTNC 2FBWC 1L0VC 3VRBD 3AE4D 3P4RC 2WU5C 5C3JD 2WP9C 2WQYD 1ZP0D 2H88D 3AE2D 3SFEC 3P4SC 3SFDC 1NEKD 2WDVC 1KFYC 1NENC 2WU2C 3ABVD 3AE8C 1E7PC 3VR9D 3AE6D 2BS4C 3AEDD 4YT0D 3AECC 4YSXC 3P4QC 3AEED 3AE9C 3CIRD 4YSYC 3AEGD 2ACZD 2H89C 1YQ4C 3AEBD 2B76D 3AEFD 3P4PD 3VRAD 3AE3D 2WS3C 3AE5D 3AEAD 1KF6C 3AE1C 2WDRC 1YQ3D 4YXDD 5C2TC 1ZOYC 3AE7D 1ZP0C 2FBWD 1L0VD 3P4RD 4YSZC 2WDQC 2WP9D 3VR8C 3SFED 4YTPD 3P4SD 4KX6C 3SFDD 2WDVD 1KFYD 4YTMD 2WU2D 2BS2C 3VRBC 3AE4C 5C3JC 2BS3C 4YTND 2WQYC 3AE3C 3AECD 2H88C 4YSXD 3AE2C 3P4QD 3AE9D 4YSYD 1NEKC 2WU5D 2H89D 1YQ4D 3ABVC 2WS3D 1KF6D 3AE1D 2WDRD 3VR9C 5C2TD 1ZOYD 3AE6C
chains in the Genus database with same CATH superfamily
1NEND 3AEDC 4YT0C 3AE8D 4YTPC 4YSZD 2WDQD 3AEEC 3CIRC 4YTMC 3AEGC 2ACZC 4DDIA 3AEBC 2B76C 3AEFC 3P4PC 3VR8D 3VRAC 3AE5C 2ZFYA 3AEAC 4KX6D 1YQ3C 4YXDC 3AE7C 1QLBC 4YTNC 2FBWC 1L0VC 3VRBD 3AE4D 3P4RC 2WU5C 5C3JD 4LDTA 2WP9C 2WQYD 1ZP0D 2H88D 3AE2D 3SFEC 3P4SC 3SFDC 1NEKD 2WDVC 1KFYC 1NENC 2WU2C 3ABVD 3AE8C 1E7PC 3VR9D 3AE6D 2BS4C 3AEDD 4DHIB 4YT0D 3AECC 4YSXC 3P4QC 3AEED 3AE9C 3CIRD 1TFFA 4YSYC 3AEGD 2ACZD 2H89C 1YQ4C 3AEBD 2B76D 3AEFD 3P4PD 3VRAD 3AE3D 2WS3C 3VONA 3AE5D 3AEAD 4DDGA 1KF6C 3AE1C 2WDRC 1YQ3D 4YXDD 5C2TC 1ZOYC 3AE7D 1ZP0C 2FBWD 1L0VD 3P4RD 4YSZC 2WDQC 2WP9D 3VR8C 3SFED 4YTPD 3P4SD 4KX6C 3SFDD 2WDVD 4I6LA 1KFYD 4YTMD 2WU2D 2BS2C 3VRBC 3AE4C 5C3JC 2BS3C 4YTND 2WQYC 3AE3C 3AECD 2H88C 4YSXD 3AE2C 3P4QD 3AE9D 4YSYD 1NEKC 2WU5D 2H89D 1YQ4D 3ABVC 4DHJA 2WS3D 1KF6D 3AE1D 2WDRD 4FJVA 3VR9C 5C2TD 1ZOYD 4DHZA 3AE6C
chains in the Genus database with same CATH topology
1NEND 3AEDC 4YT0C 3AE8D 4YTPC 4YSZD 2WDQD 3AEEC 3CIRC 4YTMC 3AEGC 2ACZC 3AEBC 2B76C 3AEFC 3P4PC 3VR8D 3VRAC 3AE5C 3AEAC 4KX6D 1YQ3C 4YXDC 3AE7C 1QLBC 4YTNC 2FBWC 1L0VC 3VRBD 3AE4D 3P4RC 2WU5C 5C3JD 2WP9C 2WQYD 1ZP0D 2H88D 3AE2D 3SFEC 3P4SC 3SFDC 1NEKD 2WDVC 1KFYC 1NENC 2WU2C 3ABVD 3AE8C 1E7PC 3VR9D 3AE6D 2BS4C 3AEDD 4YT0D 3AECC 4YSXC 3P4QC 3AEED 3AE9C 3CIRD 4YSYC 3AEGD 2ACZD 2H89C 1YQ4C 3AEBD 2B76D 3AEFD 3P4PD 3VRAD 3AE3D 2WS3C 3AE5D 3AEAD 1KF6C 3AE1C 2WDRC 1YQ3D 4YXDD 5C2TC 1ZOYC 3AE7D 1ZP0C 2FBWD 1L0VD 3P4RD 4YSZC 2WDQC 2WP9D 3VR8C 3SFED 4YTPD 3P4SD 4KX6C 3SFDD 2WDVD 1KFYD 4YTMD 2WU2D 2BS2C 3VRBC 3AE4C 5C3JC 2BS3C 4YTND 2WQYC 3AE3C 3AECD 2H88C 4YSXD 3AE2C 3P4QD 3AE9D 4YSYD 1NEKC 2WU5D 2H89D 1YQ4D 3ABVC 2WS3D 1KF6D 3AE1D 2WDRD 3VR9C 5C2TD 1ZOYD 3AE6C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NEN D;  3AED C;  4YT0 C;  3AE8 D;  4YTP C;  4YSZ D;  2WDQ D;  3AEE C;  3CIR C;  4YTM C;  3AEG C;  2ACZ C;  3AEB C;  2B76 C;  3AEF C;  3P4P C;  3VR8 D;  3VRA C;  3AE5 C;  3AEA C;  4KX6 D;  1YQ3 C;  4YXD C;  3AE7 C;  1QLB C;  4YTN C;  2FBW C;  1L0V C;  3VRB D;  3AE4 D;  3P4R C;  2WU5 C;  5C3J D;  2WP9 C;  2WQY D;  1ZP0 D;  2H88 D;  3AE2 D;  3SFE C;  3P4S C;  3SFD C;  1NEK D;  2WDV C;  1KFY C;  1NEN C;  2WU2 C;  3ABV D;  3AE8 C;  1E7P C;  3VR9 D;  3AE6 D;  2BS4 C;  3AED D;  4YT0 D;  3AEC C;  4YSX C;  3P4Q C;  3AEE D;  3AE9 C;  3CIR D;  4YSY C;  3AEG D;  2ACZ D;  2H89 C;  1YQ4 C;  3AEB D;  2B76 D;  3AEF D;  3P4P D;  3VRA D;  3AE3 D;  2WS3 C;  3AE5 D;  3AEA D;  1KF6 C;  3AE1 C;  2WDR C;  1YQ3 D;  4YXD D;  5C2T C;  1ZOY C;  3AE7 D;  1ZP0 C;  2FBW D;  1L0V D;  3P4R D;  4YSZ C;  2WDQ C;  2WP9 D;  3VR8 C;  3SFE D;  4YTP D;  3P4S D;  4KX6 C;  3SFD D;  2WDV D;  1KFY D;  4YTM D;  2WU2 D;  2BS2 C;  3VRB C;  3AE4 C;  5C3J C;  2BS3 C;  4YTN D;  2WQY C;  3AE3 C;  3AEC D;  2H88 C;  4YSX D;  3AE2 C;  3P4Q D;  3AE9 D;  4YSY D;  1NEK C;  2WU5 D;  2H89 D;  1YQ4 D;  3ABV C;  2WS3 D;  1KF6 D;  3AE1 D;  2WDR D;  3VR9 C;  5C2T D;  1ZOY D;  3AE6 C; 
#chains in the Genus database with same CATH topology
 1NEN D;  3AED C;  4YT0 C;  3AE8 D;  4YTP C;  4YSZ D;  2WDQ D;  3AEE C;  3CIR C;  4YTM C;  3AEG C;  2ACZ C;  4DDI A;  3AEB C;  2B76 C;  3AEF C;  3P4P C;  3VR8 D;  3VRA C;  3AE5 C;  2ZFY A;  3AEA C;  4KX6 D;  1YQ3 C;  4YXD C;  3AE7 C;  1QLB C;  4YTN C;  2FBW C;  1L0V C;  3VRB D;  3AE4 D;  3P4R C;  2WU5 C;  5C3J D;  4LDT A;  2WP9 C;  2WQY D;  1ZP0 D;  2H88 D;  3AE2 D;  3SFE C;  3P4S C;  3SFD C;  1NEK D;  2WDV C;  1KFY C;  1NEN C;  2WU2 C;  3ABV D;  3AE8 C;  1E7P C;  3VR9 D;  3AE6 D;  2BS4 C;  3AED D;  4DHI B;  4YT0 D;  3AEC C;  4YSX C;  3P4Q C;  3AEE D;  3AE9 C;  3CIR D;  1TFF A;  4YSY C;  3AEG D;  2ACZ D;  2H89 C;  1YQ4 C;  3AEB D;  2B76 D;  3AEF D;  3P4P D;  3VRA D;  3AE3 D;  2WS3 C;  3VON A;  3AE5 D;  3AEA D;  4DDG A;  1KF6 C;  3AE1 C;  2WDR C;  1YQ3 D;  4YXD D;  5C2T C;  1ZOY C;  3AE7 D;  1ZP0 C;  2FBW D;  1L0V D;  3P4R D;  4YSZ C;  2WDQ C;  2WP9 D;  3VR8 C;  3SFE D;  4YTP D;  3P4S D;  4KX6 C;  3SFD D;  2WDV D;  4I6L A;  1KFY D;  4YTM D;  2WU2 D;  2BS2 C;  3VRB C;  3AE4 C;  5C3J C;  2BS3 C;  4YTN D;  2WQY C;  3AE3 C;  3AEC D;  2H88 C;  4YSX D;  3AE2 C;  3P4Q D;  3AE9 D;  4YSY D;  1NEK C;  2WU5 D;  2H89 D;  1YQ4 D;  3ABV C;  4DHJ A;  2WS3 D;  1KF6 D;  3AE1 D;  2WDR D;  4FJV A;  3VR9 C;  5C2T D;  1ZOY D;  4DHZ A;  3AE6 C; 
#chains in the Genus database with same CATH homology
 1NEN D;  3AED C;  4YT0 C;  3AE8 D;  4YTP C;  4YSZ D;  2WDQ D;  3AEE C;  3CIR C;  4YTM C;  3AEG C;  2ACZ C;  3AEB C;  2B76 C;  3AEF C;  3P4P C;  3VR8 D;  3VRA C;  3AE5 C;  3AEA C;  4KX6 D;  1YQ3 C;  4YXD C;  3AE7 C;  1QLB C;  4YTN C;  2FBW C;  1L0V C;  3VRB D;  3AE4 D;  3P4R C;  2WU5 C;  5C3J D;  2WP9 C;  2WQY D;  1ZP0 D;  2H88 D;  3AE2 D;  3SFE C;  3P4S C;  3SFD C;  1NEK D;  2WDV C;  1KFY C;  1NEN C;  2WU2 C;  3ABV D;  3AE8 C;  1E7P C;  3VR9 D;  3AE6 D;  2BS4 C;  3AED D;  4YT0 D;  3AEC C;  4YSX C;  3P4Q C;  3AEE D;  3AE9 C;  3CIR D;  4YSY C;  3AEG D;  2ACZ D;  2H89 C;  1YQ4 C;  3AEB D;  2B76 D;  3AEF D;  3P4P D;  3VRA D;  3AE3 D;  2WS3 C;  3AE5 D;  3AEA D;  1KF6 C;  3AE1 C;  2WDR C;  1YQ3 D;  4YXD D;  5C2T C;  1ZOY C;  3AE7 D;  1ZP0 C;  2FBW D;  1L0V D;  3P4R D;  4YSZ C;  2WDQ C;  2WP9 D;  3VR8 C;  3SFE D;  4YTP D;  3P4S D;  4KX6 C;  3SFD D;  2WDV D;  1KFY D;  4YTM D;  2WU2 D;  2BS2 C;  3VRB C;  3AE4 C;  5C3J C;  2BS3 C;  4YTN D;  2WQY C;  3AE3 C;  3AEC D;  2H88 C;  4YSX D;  3AE2 C;  3P4Q D;  3AE9 D;  4YSY D;  1NEK C;  2WU5 D;  2H89 D;  1YQ4 D;  3ABV C;  2WS3 D;  1KF6 D;  3AE1 D;  2WDR D;  3VR9 C;  5C2T D;  1ZOY D;  3AE6 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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