4YT0C

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with 2-methyl-n-[3-(1-methylethoxy)phenyl]benzamide.
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
153
structure length
153
Chain Sequence
EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule keywords Succinate dehydrogenase flavoprotein
molecule tags Oxidoreductase/oxidoreductase inhibitor
total genus 53
structure length 153
sequence length 153
chains with identical sequence G
ec nomenclature
pdb deposition date 2015-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01127 Sdh_cyt Succinate dehydrogenase/Fumarate reductase transmembrane subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 4yt0C00
3SFDD 2WP9D 1KF6D 3AE8C 2WU5C 2WU2D 3AE9D 1QLBC 3AE7C 3AEAC 1YQ3D 3P4SC 3AEDC 4YT0D 2H88C 2FBWD 4YTMC 3VRAD 3AEFC 4YSXD 2WDRC 5C2TC 1E7PC 3AE8D 4YXDC 2WU5D 3AE4C 3AE3C 1L0VC 4YSXC 3AE7D 3AEAD 3P4SD 4YSYC 3AE6C 3AEDD 1NENC 3ABVC 3AE1C 2H88D 4YTMD 1KFYC 3AE5D 3AEFD 4YSZC 3P4PC 2WDQC 4YTPC 2WDRD 5C2TD 5C3JC 2BS3C 2WQYD 4YXDD 3AE4D 3AEBC 3AE5C 3AE3D 1L0VD 4YSYD 3AE6D 2WQYC 1ZP0C 1NEND 2BS4C 3ABVD 3AECC 2BS2C 3AE1D 3P4RC 1KFYD 3VRBC 3P4QC 4YSZD 2B76C 3P4PD 2WDQD 1ZOYC 4YTPD 5C3JD 2H89D 3AEBD 4YTNC 3VR9C 2WDVC 2WS3C 4KX6D 1ZP0D 2H89C 3AECD 3SFEC 1NEKC 3P4RD 1YQ4C 2ACZC 4KX6C 3CIRC 3AE2D 3VRBD 3P4QD 3AEED 2B76D 3VR8C 1ZOYD 3AEGC 3SFDC 4YTND 3AE2C 3VR9D 3AEEC 2WP9C 1KF6C 2WDVD 2WS3D 2WU2C 3AE9C 1YQ3C 3SFED 1NEKD 1YQ4D 2ACZD 4YT0C 3CIRD 2FBWC 3VR8D 3AEGD 3VRAC
chains in the Genus database with same CATH superfamily
3SFDD 2WP9D 1KF6D 3AE8C 4DHZA 2WU5C 2WU2D 3AE9D 1QLBC 3AE7C 3AEAC 1YQ3D 3P4SC 3AEDC 4YT0D 2H88C 2FBWD 4YTMC 3VRAD 4DDGA 3AEFC 4YSXD 2WDRC 5C2TC 1E7PC 3AE8D 4YXDC 2WU5D 3AE4C 3AE3C 1L0VC 4YSXC 3AE7D 3VONA 4DHJA 3AEAD 3P4SD 4YSYC 3AE6C 3AEDD 1NENC 3ABVC 3AE1C 2H88D 4YTMD 1KFYC 3AE5D 3AEFD 4YSZC 3P4PC 2WDQC 4YTPC 2WDRD 5C2TD 5C3JC 2BS3C 2WQYD 4YXDD 3AE4D 3AEBC 3AE5C 3AE3D 1L0VD 4LDTA 4YSYD 3AE6D 2WQYC 1ZP0C 1NEND 2BS4C 3ABVD 3AECC 2BS2C 3AE1D 3P4RC 1KFYD 3VRBC 3P4QC 4YSZD 2B76C 3P4PD 2WDQD 1ZOYC 4YTPD 5C3JD 2H89D 3AEBD 4YTNC 3VR9C 2WDVC 4FJVA 2WS3C 4KX6D 4I6LA 1ZP0D 2H89C 3AECD 3SFEC 1NEKC 3P4RD 1YQ4C 2ACZC 4KX6C 3CIRC 3AE2D 3VRBD 3P4QD 3AEED 4DHIB 2B76D 3VR8C 1ZOYD 3AEGC 3SFDC 4YTND 3AE2C 3VR9D 3AEEC 2WP9C 4DDIA 1KF6C 2WDVD 2WS3D 2WU2C 3AE9C 1YQ3C 3SFED 1NEKD 1YQ4D 2ACZD 4YT0C 3CIRD 2FBWC 1TFFA 3VR8D 2ZFYA 3AEGD 3VRAC
chains in the Genus database with same CATH topology
3SFDD 2WP9D 1KF6D 3AE8C 2WU5C 2WU2D 3AE9D 1QLBC 3AE7C 3AEAC 1YQ3D 3P4SC 3AEDC 4YT0D 2H88C 2FBWD 4YTMC 3VRAD 3AEFC 4YSXD 2WDRC 5C2TC 1E7PC 3AE8D 4YXDC 2WU5D 3AE4C 3AE3C 1L0VC 4YSXC 3AE7D 3AEAD 3P4SD 4YSYC 3AE6C 3AEDD 1NENC 3ABVC 3AE1C 2H88D 4YTMD 1KFYC 3AE5D 3AEFD 4YSZC 3P4PC 2WDQC 4YTPC 2WDRD 5C2TD 5C3JC 2BS3C 2WQYD 4YXDD 3AE4D 3AEBC 3AE5C 3AE3D 1L0VD 4YSYD 3AE6D 2WQYC 1ZP0C 1NEND 2BS4C 3ABVD 3AECC 2BS2C 3AE1D 3P4RC 1KFYD 3VRBC 3P4QC 4YSZD 2B76C 3P4PD 2WDQD 1ZOYC 4YTPD 5C3JD 2H89D 3AEBD 4YTNC 3VR9C 2WDVC 2WS3C 4KX6D 1ZP0D 2H89C 3AECD 3SFEC 1NEKC 3P4RD 1YQ4C 2ACZC 4KX6C 3CIRC 3AE2D 3VRBD 3P4QD 3AEED 2B76D 3VR8C 1ZOYD 3AEGC 3SFDC 4YTND 3AE2C 3VR9D 3AEEC 2WP9C 1KF6C 2WDVD 2WS3D 2WU2C 3AE9C 1YQ3C 3SFED 1NEKD 1YQ4D 2ACZD 4YT0C 3CIRD 2FBWC 3VR8D 3AEGD 3VRAC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SFD D;  2WP9 D;  1KF6 D;  3AE8 C;  2WU5 C;  2WU2 D;  3AE9 D;  1QLB C;  3AE7 C;  3AEA C;  1YQ3 D;  3P4S C;  3AED C;  4YT0 D;  2H88 C;  2FBW D;  4YTM C;  3VRA D;  3AEF C;  4YSX D;  2WDR C;  5C2T C;  1E7P C;  3AE8 D;  4YXD C;  2WU5 D;  3AE4 C;  3AE3 C;  1L0V C;  4YSX C;  3AE7 D;  3AEA D;  3P4S D;  4YSY C;  3AE6 C;  3AED D;  1NEN C;  3ABV C;  3AE1 C;  2H88 D;  4YTM D;  1KFY C;  3AE5 D;  3AEF D;  4YSZ C;  3P4P C;  2WDQ C;  4YTP C;  2WDR D;  5C2T D;  5C3J C;  2BS3 C;  2WQY D;  4YXD D;  3AE4 D;  3AEB C;  3AE5 C;  3AE3 D;  1L0V D;  4YSY D;  3AE6 D;  2WQY C;  1ZP0 C;  1NEN D;  2BS4 C;  3ABV D;  3AEC C;  2BS2 C;  3AE1 D;  3P4R C;  1KFY D;  3VRB C;  3P4Q C;  4YSZ D;  2B76 C;  3P4P D;  2WDQ D;  1ZOY C;  4YTP D;  5C3J D;  2H89 D;  3AEB D;  4YTN C;  3VR9 C;  2WDV C;  2WS3 C;  4KX6 D;  1ZP0 D;  2H89 C;  3AEC D;  3SFE C;  1NEK C;  3P4R D;  1YQ4 C;  2ACZ C;  4KX6 C;  3CIR C;  3AE2 D;  3VRB D;  3P4Q D;  3AEE D;  2B76 D;  3VR8 C;  1ZOY D;  3AEG C;  3SFD C;  4YTN D;  3AE2 C;  3VR9 D;  3AEE C;  2WP9 C;  1KF6 C;  2WDV D;  2WS3 D;  2WU2 C;  3AE9 C;  1YQ3 C;  3SFE D;  1NEK D;  1YQ4 D;  2ACZ D;  4YT0 C;  3CIR D;  2FBW C;  3VR8 D;  3AEG D;  3VRA C; 
#chains in the Genus database with same CATH topology
 3SFD D;  2WP9 D;  1KF6 D;  3AE8 C;  4DHZ A;  2WU5 C;  2WU2 D;  3AE9 D;  1QLB C;  3AE7 C;  3AEA C;  1YQ3 D;  3P4S C;  3AED C;  4YT0 D;  2H88 C;  2FBW D;  4YTM C;  3VRA D;  4DDG A;  3AEF C;  4YSX D;  2WDR C;  5C2T C;  1E7P C;  3AE8 D;  4YXD C;  2WU5 D;  3AE4 C;  3AE3 C;  1L0V C;  4YSX C;  3AE7 D;  3VON A;  4DHJ A;  3AEA D;  3P4S D;  4YSY C;  3AE6 C;  3AED D;  1NEN C;  3ABV C;  3AE1 C;  2H88 D;  4YTM D;  1KFY C;  3AE5 D;  3AEF D;  4YSZ C;  3P4P C;  2WDQ C;  4YTP C;  2WDR D;  5C2T D;  5C3J C;  2BS3 C;  2WQY D;  4YXD D;  3AE4 D;  3AEB C;  3AE5 C;  3AE3 D;  1L0V D;  4LDT A;  4YSY D;  3AE6 D;  2WQY C;  1ZP0 C;  1NEN D;  2BS4 C;  3ABV D;  3AEC C;  2BS2 C;  3AE1 D;  3P4R C;  1KFY D;  3VRB C;  3P4Q C;  4YSZ D;  2B76 C;  3P4P D;  2WDQ D;  1ZOY C;  4YTP D;  5C3J D;  2H89 D;  3AEB D;  4YTN C;  3VR9 C;  2WDV C;  4FJV A;  2WS3 C;  4KX6 D;  4I6L A;  1ZP0 D;  2H89 C;  3AEC D;  3SFE C;  1NEK C;  3P4R D;  1YQ4 C;  2ACZ C;  4KX6 C;  3CIR C;  3AE2 D;  3VRB D;  3P4Q D;  3AEE D;  4DHI B;  2B76 D;  3VR8 C;  1ZOY D;  3AEG C;  3SFD C;  4YTN D;  3AE2 C;  3VR9 D;  3AEE C;  2WP9 C;  4DDI A;  1KF6 C;  2WDV D;  2WS3 D;  2WU2 C;  3AE9 C;  1YQ3 C;  3SFE D;  1NEK D;  1YQ4 D;  2ACZ D;  4YT0 C;  3CIR D;  2FBW C;  1TFF A;  3VR8 D;  2ZFY A;  3AEG D;  3VRA C; 
#chains in the Genus database with same CATH homology
 3SFD D;  2WP9 D;  1KF6 D;  3AE8 C;  2WU5 C;  2WU2 D;  3AE9 D;  1QLB C;  3AE7 C;  3AEA C;  1YQ3 D;  3P4S C;  3AED C;  4YT0 D;  2H88 C;  2FBW D;  4YTM C;  3VRA D;  3AEF C;  4YSX D;  2WDR C;  5C2T C;  1E7P C;  3AE8 D;  4YXD C;  2WU5 D;  3AE4 C;  3AE3 C;  1L0V C;  4YSX C;  3AE7 D;  3AEA D;  3P4S D;  4YSY C;  3AE6 C;  3AED D;  1NEN C;  3ABV C;  3AE1 C;  2H88 D;  4YTM D;  1KFY C;  3AE5 D;  3AEF D;  4YSZ C;  3P4P C;  2WDQ C;  4YTP C;  2WDR D;  5C2T D;  5C3J C;  2BS3 C;  2WQY D;  4YXD D;  3AE4 D;  3AEB C;  3AE5 C;  3AE3 D;  1L0V D;  4YSY D;  3AE6 D;  2WQY C;  1ZP0 C;  1NEN D;  2BS4 C;  3ABV D;  3AEC C;  2BS2 C;  3AE1 D;  3P4R C;  1KFY D;  3VRB C;  3P4Q C;  4YSZ D;  2B76 C;  3P4P D;  2WDQ D;  1ZOY C;  4YTP D;  5C3J D;  2H89 D;  3AEB D;  4YTN C;  3VR9 C;  2WDV C;  2WS3 C;  4KX6 D;  1ZP0 D;  2H89 C;  3AEC D;  3SFE C;  1NEK C;  3P4R D;  1YQ4 C;  2ACZ C;  4KX6 C;  3CIR C;  3AE2 D;  3VRB D;  3P4Q D;  3AEE D;  2B76 D;  3VR8 C;  1ZOY D;  3AEG C;  3SFD C;  4YTN D;  3AE2 C;  3VR9 D;  3AEE C;  2WP9 C;  1KF6 C;  2WDV D;  2WS3 D;  2WU2 C;  3AE9 C;  1YQ3 C;  3SFE D;  1NEK D;  1YQ4 D;  2ACZ D;  4YT0 C;  3CIR D;  2FBW C;  3VR8 D;  3AEG D;  3VRA C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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