4YT0D

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with 2-methyl-n-[3-(1-methylethoxy)phenyl]benzamide.
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
129
structure length
129
Chain Sequence
TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase flavoprotein
total genus 41
structure length 129
sequence length 129
chains with identical sequence H
ec nomenclature
pdb deposition date 2015-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05328 CybS CybS, succinate dehydrogenase cytochrome B small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 4yt0D00
1NEKD 3AEBD 1ZP0C 3VRBC 2WDVC 3VRBD 4YTMC 3AEDD 1QLBC 3P4RC 1NENC 3VRAC 4YSXD 3AEFC 3AECD 3P4QD 3AE7C 1KF6D 3AE7D 3AE1D 2WDRC 5C2TC 3AEEC 3AE4C 3CIRC 1YQ4D 1YQ3D 3AE4D 3AE5D 3P4SC 2WP9C 3AE6C 3P4SD 2WS3D 1NEKC 1E7PC 4YT0D 3SFED 3AEDC 3AEAD 2WQYD 3AE8D 4YSXC 3AE3D 2H89D 3AECC 2H88D 3P4QC 1KFYD 4YSYD 3VR9D 1KF6C 4YTNC 3AE2D 3AE1C 3AE9D 4YTND 1YQ4C 1YQ3C 2ACZD 2FBWD 3AE5C 3VR8D 2BS2C 2WS3C 3P4PC 4YSZD 3P4PD 4YT0C 3SFEC 5C3JD 3AEAC 2WDQD 2WQYC 3AE8C 3AE3C 2H89C 1ZOYD 2H88C 1KFYC 4YSYC 3VR9C 3AE2C 2WU5C 3AE9C 3SFDD 2WU5D 4YXDD 2WU2D 2B76D 3AEGD 2ACZC 4KX6D 4YTPD 2FBWC 3VR8C 3ABVD 2BS3C 4YSZC 1L0VD 5C3JC 1ZP0D 2WDQC 2WDVD 4YTMD 3P4RD 1NEND 1ZOYC 3VRAD 3AEFD 3SFDC 4YXDC 2WDRD 2WU2C 2B76C 3AEGC 4KX6C 4YTPC 5C2TD 3AEED 2BS4C 3CIRD 3ABVC 2WP9D 1L0VC 3AE6D 3AEBC
chains in the Genus database with same CATH superfamily
1NEKD 3AEBD 1ZP0C 3VRBC 2WDVC 3VRBD 4YTMC 3AEDD 1QLBC 3P4RC 1NENC 3VRAC 4YSXD 3AEFC 3AECD 2ZFYA 3P4QD 3AE7C 1KF6D 3AE7D 3AE1D 2WDRC 5C2TC 3AEEC 3AE4C 3CIRC 1YQ4D 1YQ3D 3AE4D 4DHZA 3AE5D 3P4SC 4DHIB 2WP9C 3AE6C 3P4SD 2WS3D 4FJVA 1NEKC 4DDIA 1E7PC 4YT0D 3SFED 3AEDC 3AEAD 2WQYD 3AE8D 4YSXC 3AE3D 2H89D 3AECC 2H88D 3P4QC 1KFYD 4YSYD 3VR9D 1KF6C 4YTNC 3AE2D 3AE1C 4LDTA 3AE9D 4YTND 4I6LA 1YQ4C 1YQ3C 2ACZD 2FBWD 3AE5C 3VR8D 2BS2C 2WS3C 3P4PC 4YSZD 1TFFA 3P4PD 4YT0C 4DDGA 3SFEC 5C3JD 4DHJA 3AEAC 2WDQD 2WQYC 3AE8C 3AE3C 2H89C 1ZOYD 2H88C 1KFYC 4YSYC 3VR9C 3AE2C 2WU5C 3AE9C 3SFDD 2WU5D 4YXDD 2WU2D 2B76D 3AEGD 2ACZC 4KX6D 4YTPD 2FBWC 3VR8C 3ABVD 2BS3C 4YSZC 1L0VD 3VONA 5C3JC 1ZP0D 2WDQC 2WDVD 4YTMD 3P4RD 1NEND 1ZOYC 3VRAD 3AEFD 3SFDC 4YXDC 2WDRD 2WU2C 2B76C 3AEGC 4KX6C 4YTPC 5C2TD 3AEED 2BS4C 3CIRD 3ABVC 2WP9D 1L0VC 3AE6D 3AEBC
chains in the Genus database with same CATH topology
1NEKD 3AEBD 1ZP0C 3VRBC 2WDVC 3VRBD 4YTMC 3AEDD 1QLBC 3P4RC 1NENC 3VRAC 4YSXD 3AEFC 3AECD 3P4QD 3AE7C 1KF6D 3AE7D 3AE1D 2WDRC 5C2TC 3AEEC 3AE4C 3CIRC 1YQ4D 1YQ3D 3AE4D 3AE5D 3P4SC 2WP9C 3AE6C 3P4SD 2WS3D 1NEKC 1E7PC 4YT0D 3SFED 3AEDC 3AEAD 2WQYD 3AE8D 4YSXC 3AE3D 2H89D 3AECC 2H88D 3P4QC 1KFYD 4YSYD 3VR9D 1KF6C 4YTNC 3AE2D 3AE1C 3AE9D 4YTND 1YQ4C 1YQ3C 2ACZD 2FBWD 3AE5C 3VR8D 2BS2C 2WS3C 3P4PC 4YSZD 3P4PD 4YT0C 3SFEC 5C3JD 3AEAC 2WDQD 2WQYC 3AE8C 3AE3C 2H89C 1ZOYD 2H88C 1KFYC 4YSYC 3VR9C 3AE2C 2WU5C 3AE9C 3SFDD 2WU5D 4YXDD 2WU2D 2B76D 3AEGD 2ACZC 4KX6D 4YTPD 2FBWC 3VR8C 3ABVD 2BS3C 4YSZC 1L0VD 5C3JC 1ZP0D 2WDQC 2WDVD 4YTMD 3P4RD 1NEND 1ZOYC 3VRAD 3AEFD 3SFDC 4YXDC 2WDRD 2WU2C 2B76C 3AEGC 4KX6C 4YTPC 5C2TD 3AEED 2BS4C 3CIRD 3ABVC 2WP9D 1L0VC 3AE6D 3AEBC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NEK D;  3AEB D;  1ZP0 C;  3VRB C;  2WDV C;  3VRB D;  4YTM C;  3AED D;  1QLB C;  3P4R C;  1NEN C;  3VRA C;  4YSX D;  3AEF C;  3AEC D;  3P4Q D;  3AE7 C;  1KF6 D;  3AE7 D;  3AE1 D;  2WDR C;  5C2T C;  3AEE C;  3AE4 C;  3CIR C;  1YQ4 D;  1YQ3 D;  3AE4 D;  3AE5 D;  3P4S C;  2WP9 C;  3AE6 C;  3P4S D;  2WS3 D;  1NEK C;  1E7P C;  4YT0 D;  3SFE D;  3AED C;  3AEA D;  2WQY D;  3AE8 D;  4YSX C;  3AE3 D;  2H89 D;  3AEC C;  2H88 D;  3P4Q C;  1KFY D;  4YSY D;  3VR9 D;  1KF6 C;  4YTN C;  3AE2 D;  3AE1 C;  3AE9 D;  4YTN D;  1YQ4 C;  1YQ3 C;  2ACZ D;  2FBW D;  3AE5 C;  3VR8 D;  2BS2 C;  2WS3 C;  3P4P C;  4YSZ D;  3P4P D;  4YT0 C;  3SFE C;  5C3J D;  3AEA C;  2WDQ D;  2WQY C;  3AE8 C;  3AE3 C;  2H89 C;  1ZOY D;  2H88 C;  1KFY C;  4YSY C;  3VR9 C;  3AE2 C;  2WU5 C;  3AE9 C;  3SFD D;  2WU5 D;  4YXD D;  2WU2 D;  2B76 D;  3AEG D;  2ACZ C;  4KX6 D;  4YTP D;  2FBW C;  3VR8 C;  3ABV D;  2BS3 C;  4YSZ C;  1L0V D;  5C3J C;  1ZP0 D;  2WDQ C;  2WDV D;  4YTM D;  3P4R D;  1NEN D;  1ZOY C;  3VRA D;  3AEF D;  3SFD C;  4YXD C;  2WDR D;  2WU2 C;  2B76 C;  3AEG C;  4KX6 C;  4YTP C;  5C2T D;  3AEE D;  2BS4 C;  3CIR D;  3ABV C;  2WP9 D;  1L0V C;  3AE6 D;  3AEB C; 
#chains in the Genus database with same CATH topology
 1NEK D;  3AEB D;  1ZP0 C;  3VRB C;  2WDV C;  3VRB D;  4YTM C;  3AED D;  1QLB C;  3P4R C;  1NEN C;  3VRA C;  4YSX D;  3AEF C;  3AEC D;  2ZFY A;  3P4Q D;  3AE7 C;  1KF6 D;  3AE7 D;  3AE1 D;  2WDR C;  5C2T C;  3AEE C;  3AE4 C;  3CIR C;  1YQ4 D;  1YQ3 D;  3AE4 D;  4DHZ A;  3AE5 D;  3P4S C;  4DHI B;  2WP9 C;  3AE6 C;  3P4S D;  2WS3 D;  4FJV A;  1NEK C;  4DDI A;  1E7P C;  4YT0 D;  3SFE D;  3AED C;  3AEA D;  2WQY D;  3AE8 D;  4YSX C;  3AE3 D;  2H89 D;  3AEC C;  2H88 D;  3P4Q C;  1KFY D;  4YSY D;  3VR9 D;  1KF6 C;  4YTN C;  3AE2 D;  3AE1 C;  4LDT A;  3AE9 D;  4YTN D;  4I6L A;  1YQ4 C;  1YQ3 C;  2ACZ D;  2FBW D;  3AE5 C;  3VR8 D;  2BS2 C;  2WS3 C;  3P4P C;  4YSZ D;  1TFF A;  3P4P D;  4YT0 C;  4DDG A;  3SFE C;  5C3J D;  4DHJ A;  3AEA C;  2WDQ D;  2WQY C;  3AE8 C;  3AE3 C;  2H89 C;  1ZOY D;  2H88 C;  1KFY C;  4YSY C;  3VR9 C;  3AE2 C;  2WU5 C;  3AE9 C;  3SFD D;  2WU5 D;  4YXD D;  2WU2 D;  2B76 D;  3AEG D;  2ACZ C;  4KX6 D;  4YTP D;  2FBW C;  3VR8 C;  3ABV D;  2BS3 C;  4YSZ C;  1L0V D;  3VON A;  5C3J C;  1ZP0 D;  2WDQ C;  2WDV D;  4YTM D;  3P4R D;  1NEN D;  1ZOY C;  3VRA D;  3AEF D;  3SFD C;  4YXD C;  2WDR D;  2WU2 C;  2B76 C;  3AEG C;  4KX6 C;  4YTP C;  5C2T D;  3AEE D;  2BS4 C;  3CIR D;  3ABV C;  2WP9 D;  1L0V C;  3AE6 D;  3AEB C; 
#chains in the Genus database with same CATH homology
 1NEK D;  3AEB D;  1ZP0 C;  3VRB C;  2WDV C;  3VRB D;  4YTM C;  3AED D;  1QLB C;  3P4R C;  1NEN C;  3VRA C;  4YSX D;  3AEF C;  3AEC D;  3P4Q D;  3AE7 C;  1KF6 D;  3AE7 D;  3AE1 D;  2WDR C;  5C2T C;  3AEE C;  3AE4 C;  3CIR C;  1YQ4 D;  1YQ3 D;  3AE4 D;  3AE5 D;  3P4S C;  2WP9 C;  3AE6 C;  3P4S D;  2WS3 D;  1NEK C;  1E7P C;  4YT0 D;  3SFE D;  3AED C;  3AEA D;  2WQY D;  3AE8 D;  4YSX C;  3AE3 D;  2H89 D;  3AEC C;  2H88 D;  3P4Q C;  1KFY D;  4YSY D;  3VR9 D;  1KF6 C;  4YTN C;  3AE2 D;  3AE1 C;  3AE9 D;  4YTN D;  1YQ4 C;  1YQ3 C;  2ACZ D;  2FBW D;  3AE5 C;  3VR8 D;  2BS2 C;  2WS3 C;  3P4P C;  4YSZ D;  3P4P D;  4YT0 C;  3SFE C;  5C3J D;  3AEA C;  2WDQ D;  2WQY C;  3AE8 C;  3AE3 C;  2H89 C;  1ZOY D;  2H88 C;  1KFY C;  4YSY C;  3VR9 C;  3AE2 C;  2WU5 C;  3AE9 C;  3SFD D;  2WU5 D;  4YXD D;  2WU2 D;  2B76 D;  3AEG D;  2ACZ C;  4KX6 D;  4YTP D;  2FBW C;  3VR8 C;  3ABV D;  2BS3 C;  4YSZ C;  1L0V D;  5C3J C;  1ZP0 D;  2WDQ C;  2WDV D;  4YTM D;  3P4R D;  1NEN D;  1ZOY C;  3VRA D;  3AEF D;  3SFD C;  4YXD C;  2WDR D;  2WU2 C;  2B76 C;  3AEG C;  4KX6 C;  4YTP C;  5C2T D;  3AEE D;  2BS4 C;  3CIR D;  3ABV C;  2WP9 D;  1L0V C;  3AE6 D;  3AEB C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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