4YTMC

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with n-biphenyl-3-yl-2-(trifluoromethyl)benzamide
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
152
structure length
152
Chain Sequence
EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule keywords Succinate dehydrogenase flavoprotein
molecule tags Oxidoreductase/oxidoreductase inhibitor
total genus 53
structure length 152
sequence length 152
chains with identical sequence G
ec nomenclature
pdb deposition date 2015-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01127 Sdh_cyt Succinate dehydrogenase/Fumarate reductase transmembrane subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 4ytmC00
2B76D 3AEAD 4YSXD 2WS3C 3SFDC 5C2TC 4YTND 3ABVC 3AE4D 3SFED 4YSYC 1NENC 3AEDD 3P4SD 3VRBD 2BS2C 3P4PC 2H88C 3AEBC 1YQ3D 2WP9D 3VR9D 2WDVC 2BS3C 2H89C 3AEGC 3AE2D 1YQ4C 1ZOYD 3AEFC 5C3JD 2ACZD 4YSZC 4YTPC 4YT0C 3AE3C 3AE7C 1NEKD 2WDQC 3AE8C 2WDRC 3SFDD 1KF6C 2B76C 3AEAC 3ABVD 4YSXC 1NEND 1QLBC 2H88D 3AE6D 3CIRC 1E7PC 1KFYC 3AEBD 1ZP0D 3AE9D 3AE1D 3AE4C 3P4QC 3P4RD 2FBWC 3AEEC 4KX6C 1YQ4D 3AEFD 3AE5C 3VRBC 3VRAD 1L0VC 3AECD 4YXDC 1YQ3C 2WP9C 3VR9C 2WQYC 4YTPD 4YT0D 2WS3D 2WU5C 2WDQD 2WU2C 2ACZC 3VR8C 4YTMC 3AE8D 5C2TD 2WDRD 4YSYD 1KF6D 3P4PD 2BS4C 4YTNC 2WDVD 3SFEC 2H89D 3AEDC 3AEGD 3CIRD 3P4SC 1KFYD 3P4QD 4KX6D 2FBWD 3AEED 4YSZD 3AE5D 3AE2C 1L0VD 3AE3D 1ZOYC 3AE7D 3AE6C 4YXDD 5C3JC 1ZP0C 3AE9C 2WQYD 3AE1C 3P4RC 3VRAC 2WU5D 3AECC 2WU2D 1NEKC 3VR8D 4YTMD
chains in the Genus database with same CATH superfamily
2B76D 3VONA 1TFFA 3AEAD 4YSXD 2WS3C 3SFDC 5C2TC 4YTND 3ABVC 3AE4D 3SFED 4YSYC 1NENC 3AEDD 3P4SD 3VRBD 2BS2C 3P4PC 2H88C 4DHJA 3AEBC 1YQ3D 2WP9D 3VR9D 2WDVC 2BS3C 2H89C 3AEGC 3AE2D 1YQ4C 1ZOYD 3AEFC 5C3JD 4DHZA 2ACZD 4YSZC 2ZFYA 4YTPC 4YT0C 3AE3C 3AE7C 1NEKD 2WDQC 3AE8C 4LDTA 2WDRC 3SFDD 1KF6C 2B76C 3AEAC 3ABVD 4YSXC 1NEND 1QLBC 4FJVA 2H88D 3AE6D 3CIRC 1E7PC 1KFYC 3AEBD 1ZP0D 3AE9D 3AE1D 3AE4C 3P4QC 3P4RD 2FBWC 3AEEC 4KX6C 1YQ4D 3AEFD 3AE5C 3VRBC 3VRAD 1L0VC 3AECD 4DDIA 4YXDC 1YQ3C 2WP9C 3VR9C 2WQYC 4YTPD 4YT0D 2WS3D 4DDGA 2WU5C 2WDQD 2WU2C 2ACZC 3VR8C 4YTMC 3AE8D 5C2TD 2WDRD 4YSYD 1KF6D 4I6LA 3P4PD 2BS4C 4YTNC 2WDVD 3SFEC 2H89D 3AEDC 3AEGD 3CIRD 3P4SC 1KFYD 3P4QD 4DHIB 4KX6D 2FBWD 3AEED 4YSZD 3AE5D 3AE2C 1L0VD 3AE3D 1ZOYC 3AE7D 3AE6C 4YXDD 5C3JC 1ZP0C 3AE9C 2WQYD 3AE1C 3P4RC 3VRAC 2WU5D 3AECC 2WU2D 1NEKC 3VR8D 4YTMD
chains in the Genus database with same CATH topology
2B76D 3AEAD 4YSXD 2WS3C 3SFDC 5C2TC 4YTND 3ABVC 3AE4D 3SFED 4YSYC 1NENC 3AEDD 3P4SD 3VRBD 2BS2C 3P4PC 2H88C 3AEBC 1YQ3D 2WP9D 3VR9D 2WDVC 2BS3C 2H89C 3AEGC 3AE2D 1YQ4C 1ZOYD 3AEFC 5C3JD 2ACZD 4YSZC 4YTPC 4YT0C 3AE3C 3AE7C 1NEKD 2WDQC 3AE8C 2WDRC 3SFDD 1KF6C 2B76C 3AEAC 3ABVD 4YSXC 1NEND 1QLBC 2H88D 3AE6D 3CIRC 1E7PC 1KFYC 3AEBD 1ZP0D 3AE9D 3AE1D 3AE4C 3P4QC 3P4RD 2FBWC 3AEEC 4KX6C 1YQ4D 3AEFD 3AE5C 3VRBC 3VRAD 1L0VC 3AECD 4YXDC 1YQ3C 2WP9C 3VR9C 2WQYC 4YTPD 4YT0D 2WS3D 2WU5C 2WDQD 2WU2C 2ACZC 3VR8C 4YTMC 3AE8D 5C2TD 2WDRD 4YSYD 1KF6D 3P4PD 2BS4C 4YTNC 2WDVD 3SFEC 2H89D 3AEDC 3AEGD 3CIRD 3P4SC 1KFYD 3P4QD 4KX6D 2FBWD 3AEED 4YSZD 3AE5D 3AE2C 1L0VD 3AE3D 1ZOYC 3AE7D 3AE6C 4YXDD 5C3JC 1ZP0C 3AE9C 2WQYD 3AE1C 3P4RC 3VRAC 2WU5D 3AECC 2WU2D 1NEKC 3VR8D 4YTMD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2B76 D;  3AEA D;  4YSX D;  2WS3 C;  3SFD C;  5C2T C;  4YTN D;  3ABV C;  3AE4 D;  3SFE D;  4YSY C;  1NEN C;  3AED D;  3P4S D;  3VRB D;  2BS2 C;  3P4P C;  2H88 C;  3AEB C;  1YQ3 D;  2WP9 D;  3VR9 D;  2WDV C;  2BS3 C;  2H89 C;  3AEG C;  3AE2 D;  1YQ4 C;  1ZOY D;  3AEF C;  5C3J D;  2ACZ D;  4YSZ C;  4YTP C;  4YT0 C;  3AE3 C;  3AE7 C;  1NEK D;  2WDQ C;  3AE8 C;  2WDR C;  3SFD D;  1KF6 C;  2B76 C;  3AEA C;  3ABV D;  4YSX C;  1NEN D;  1QLB C;  2H88 D;  3AE6 D;  3CIR C;  1E7P C;  1KFY C;  3AEB D;  1ZP0 D;  3AE9 D;  3AE1 D;  3AE4 C;  3P4Q C;  3P4R D;  2FBW C;  3AEE C;  4KX6 C;  1YQ4 D;  3AEF D;  3AE5 C;  3VRB C;  3VRA D;  1L0V C;  3AEC D;  4YXD C;  1YQ3 C;  2WP9 C;  3VR9 C;  2WQY C;  4YTP D;  4YT0 D;  2WS3 D;  2WU5 C;  2WDQ D;  2WU2 C;  2ACZ C;  3VR8 C;  4YTM C;  3AE8 D;  5C2T D;  2WDR D;  4YSY D;  1KF6 D;  3P4P D;  2BS4 C;  4YTN C;  2WDV D;  3SFE C;  2H89 D;  3AED C;  3AEG D;  3CIR D;  3P4S C;  1KFY D;  3P4Q D;  4KX6 D;  2FBW D;  3AEE D;  4YSZ D;  3AE5 D;  3AE2 C;  1L0V D;  3AE3 D;  1ZOY C;  3AE7 D;  3AE6 C;  4YXD D;  5C3J C;  1ZP0 C;  3AE9 C;  2WQY D;  3AE1 C;  3P4R C;  3VRA C;  2WU5 D;  3AEC C;  2WU2 D;  1NEK C;  3VR8 D;  4YTM D; 
#chains in the Genus database with same CATH topology
 2B76 D;  3VON A;  1TFF A;  3AEA D;  4YSX D;  2WS3 C;  3SFD C;  5C2T C;  4YTN D;  3ABV C;  3AE4 D;  3SFE D;  4YSY C;  1NEN C;  3AED D;  3P4S D;  3VRB D;  2BS2 C;  3P4P C;  2H88 C;  4DHJ A;  3AEB C;  1YQ3 D;  2WP9 D;  3VR9 D;  2WDV C;  2BS3 C;  2H89 C;  3AEG C;  3AE2 D;  1YQ4 C;  1ZOY D;  3AEF C;  5C3J D;  4DHZ A;  2ACZ D;  4YSZ C;  2ZFY A;  4YTP C;  4YT0 C;  3AE3 C;  3AE7 C;  1NEK D;  2WDQ C;  3AE8 C;  4LDT A;  2WDR C;  3SFD D;  1KF6 C;  2B76 C;  3AEA C;  3ABV D;  4YSX C;  1NEN D;  1QLB C;  4FJV A;  2H88 D;  3AE6 D;  3CIR C;  1E7P C;  1KFY C;  3AEB D;  1ZP0 D;  3AE9 D;  3AE1 D;  3AE4 C;  3P4Q C;  3P4R D;  2FBW C;  3AEE C;  4KX6 C;  1YQ4 D;  3AEF D;  3AE5 C;  3VRB C;  3VRA D;  1L0V C;  3AEC D;  4DDI A;  4YXD C;  1YQ3 C;  2WP9 C;  3VR9 C;  2WQY C;  4YTP D;  4YT0 D;  2WS3 D;  4DDG A;  2WU5 C;  2WDQ D;  2WU2 C;  2ACZ C;  3VR8 C;  4YTM C;  3AE8 D;  5C2T D;  2WDR D;  4YSY D;  1KF6 D;  4I6L A;  3P4P D;  2BS4 C;  4YTN C;  2WDV D;  3SFE C;  2H89 D;  3AED C;  3AEG D;  3CIR D;  3P4S C;  1KFY D;  3P4Q D;  4DHI B;  4KX6 D;  2FBW D;  3AEE D;  4YSZ D;  3AE5 D;  3AE2 C;  1L0V D;  3AE3 D;  1ZOY C;  3AE7 D;  3AE6 C;  4YXD D;  5C3J C;  1ZP0 C;  3AE9 C;  2WQY D;  3AE1 C;  3P4R C;  3VRA C;  2WU5 D;  3AEC C;  2WU2 D;  1NEK C;  3VR8 D;  4YTM D; 
#chains in the Genus database with same CATH homology
 2B76 D;  3AEA D;  4YSX D;  2WS3 C;  3SFD C;  5C2T C;  4YTN D;  3ABV C;  3AE4 D;  3SFE D;  4YSY C;  1NEN C;  3AED D;  3P4S D;  3VRB D;  2BS2 C;  3P4P C;  2H88 C;  3AEB C;  1YQ3 D;  2WP9 D;  3VR9 D;  2WDV C;  2BS3 C;  2H89 C;  3AEG C;  3AE2 D;  1YQ4 C;  1ZOY D;  3AEF C;  5C3J D;  2ACZ D;  4YSZ C;  4YTP C;  4YT0 C;  3AE3 C;  3AE7 C;  1NEK D;  2WDQ C;  3AE8 C;  2WDR C;  3SFD D;  1KF6 C;  2B76 C;  3AEA C;  3ABV D;  4YSX C;  1NEN D;  1QLB C;  2H88 D;  3AE6 D;  3CIR C;  1E7P C;  1KFY C;  3AEB D;  1ZP0 D;  3AE9 D;  3AE1 D;  3AE4 C;  3P4Q C;  3P4R D;  2FBW C;  3AEE C;  4KX6 C;  1YQ4 D;  3AEF D;  3AE5 C;  3VRB C;  3VRA D;  1L0V C;  3AEC D;  4YXD C;  1YQ3 C;  2WP9 C;  3VR9 C;  2WQY C;  4YTP D;  4YT0 D;  2WS3 D;  2WU5 C;  2WDQ D;  2WU2 C;  2ACZ C;  3VR8 C;  4YTM C;  3AE8 D;  5C2T D;  2WDR D;  4YSY D;  1KF6 D;  3P4P D;  2BS4 C;  4YTN C;  2WDV D;  3SFE C;  2H89 D;  3AED C;  3AEG D;  3CIR D;  3P4S C;  1KFY D;  3P4Q D;  4KX6 D;  2FBW D;  3AEE D;  4YSZ D;  3AE5 D;  3AE2 C;  1L0V D;  3AE3 D;  1ZOY C;  3AE7 D;  3AE6 C;  4YXD D;  5C3J C;  1ZP0 C;  3AE9 C;  2WQY D;  3AE1 C;  3P4R C;  3VRA C;  2WU5 D;  3AEC C;  2WU2 D;  1NEK C;  3VR8 D;  4YTM D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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