4YTMD

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with n-biphenyl-3-yl-2-(trifluoromethyl)benzamide
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
129
structure length
129
Chain Sequence
TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase flavoprotein
total genus 37
structure length 129
sequence length 129
chains with identical sequence H
ec nomenclature
pdb deposition date 2015-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05328 CybS CybS, succinate dehydrogenase cytochrome B small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 4ytmD00
4YTMD 4YSZD 2ACZC 1NEND 3AE4D 3VR8D 4YXDD 1YQ3C 3SFED 2WDRD 2H89C 3SFDC 3AEAD 3AEBC 1KF6C 2B76C 1L0VC 2ACZD 2WDQC 2WU2D 1ZP0C 3AE6C 2H89D 3SFDD 3VRBC 3VR9D 2WDVC 3AEDC 2WU5C 1KF6D 1NEKD 2B76D 1L0VD 2FBWD 3ABVC 4KX6D 1ZP0D 3P4PC 3AEGC 3VRBD 2WDVD 1ZOYC 3AEDD 1QLBC 5C3JC 1YQ4D 2WS3C 3P4SC 3P4RC 2WP9C 3AEFC 1YQ3D 4YSYC 3VRAC 3P4PD 3AEEC 3AE9C 3AEGD 1E7PC 1ZOYD 3AEBD 3CIRC 5C3JD 2WS3D 4YTPC 3P4RD 2BS2C 2WP9D 5C2TC 2WDQD 2BS3C 3AEFD 3AE2C 4YTNC 3AE3C 4YSYD 4YTMC 3AE6D 3AEED 3AE9D 3AE5C 3VR8C 3SFEC 2WU5D 2WQYC 4YSXC 3AE1C 3AE7C 4YTPD 3AECC 3ABVD 5C2TD 4YTND 2H88C 3AE2D 3AE3D 1KFYC 3AE5D 2WQYD 2WU2C 4YSXD 3AE1D 4YT0C 3P4QC 3AE8C 1YQ4C 3AE7D 3P4SD 3AECD 2BS4C 3VR9C 2H88D 3VRAD 1NEKC 1KFYD 4YSZC 1NENC 3AE4C 2FBWC 4YXDC 4KX6C 2WDRC 3CIRD 4YT0D 3P4QD 3AE8D 3AEAC
chains in the Genus database with same CATH superfamily
4LDTA 4YTMD 4YSZD 2ACZC 1NEND 3AE4D 3VR8D 3VONA 4YXDD 1YQ3C 3SFED 2WDRD 2H89C 3SFDC 3AEAD 3AEBC 1KF6C 2B76C 1L0VC 2ACZD 2WDQC 2WU2D 1ZP0C 3AE6C 2H89D 3SFDD 3VRBC 3VR9D 2WDVC 3AEDC 2WU5C 1KF6D 1NEKD 2B76D 1L0VD 2FBWD 3ABVC 4KX6D 1ZP0D 2ZFYA 3P4PC 3AEGC 3VRBD 2WDVD 1ZOYC 3AEDD 1QLBC 4DDIA 4DHJA 5C3JC 1YQ4D 2WS3C 3P4SC 3P4RC 2WP9C 3AEFC 1YQ3D 4YSYC 3VRAC 3P4PD 3AEEC 3AE9C 3AEGD 1E7PC 1ZOYD 3AEBD 3CIRC 4FJVA 5C3JD 2WS3D 4YTPC 3P4RD 2BS2C 2WP9D 5C2TC 2WDQD 2BS3C 3AEFD 3AE2C 4YTNC 3AE3C 4YSYD 4YTMC 3AE6D 3AEED 3AE9D 3AE5C 3VR8C 3SFEC 2WU5D 2WQYC 4YSXC 1TFFA 3AE1C 3AE7C 4YTPD 3AECC 3ABVD 5C2TD 4YTND 2H88C 3AE2D 3AE3D 1KFYC 3AE5D 2WQYD 2WU2C 4YSXD 3AE1D 4YT0C 3P4QC 4DHZA 3AE8C 1YQ4C 3AE7D 3P4SD 3AECD 2BS4C 3VR9C 2H88D 4DHIB 3VRAD 1NEKC 1KFYD 4YSZC 1NENC 3AE4C 2FBWC 4I6LA 4YXDC 4KX6C 2WDRC 3CIRD 4DDGA 4YT0D 3P4QD 3AE8D 3AEAC
chains in the Genus database with same CATH topology
4YTMD 4YSZD 2ACZC 1NEND 3AE4D 3VR8D 4YXDD 1YQ3C 3SFED 2WDRD 2H89C 3SFDC 3AEAD 3AEBC 1KF6C 2B76C 1L0VC 2ACZD 2WDQC 2WU2D 1ZP0C 3AE6C 2H89D 3SFDD 3VRBC 3VR9D 2WDVC 3AEDC 2WU5C 1KF6D 1NEKD 2B76D 1L0VD 2FBWD 3ABVC 4KX6D 1ZP0D 3P4PC 3AEGC 3VRBD 2WDVD 1ZOYC 3AEDD 1QLBC 5C3JC 1YQ4D 2WS3C 3P4SC 3P4RC 2WP9C 3AEFC 1YQ3D 4YSYC 3VRAC 3P4PD 3AEEC 3AE9C 3AEGD 1E7PC 1ZOYD 3AEBD 3CIRC 5C3JD 2WS3D 4YTPC 3P4RD 2BS2C 2WP9D 5C2TC 2WDQD 2BS3C 3AEFD 3AE2C 4YTNC 3AE3C 4YSYD 4YTMC 3AE6D 3AEED 3AE9D 3AE5C 3VR8C 3SFEC 2WU5D 2WQYC 4YSXC 3AE1C 3AE7C 4YTPD 3AECC 3ABVD 5C2TD 4YTND 2H88C 3AE2D 3AE3D 1KFYC 3AE5D 2WQYD 2WU2C 4YSXD 3AE1D 4YT0C 3P4QC 3AE8C 1YQ4C 3AE7D 3P4SD 3AECD 2BS4C 3VR9C 2H88D 3VRAD 1NEKC 1KFYD 4YSZC 1NENC 3AE4C 2FBWC 4YXDC 4KX6C 2WDRC 3CIRD 4YT0D 3P4QD 3AE8D 3AEAC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YTM D;  4YSZ D;  2ACZ C;  1NEN D;  3AE4 D;  3VR8 D;  4YXD D;  1YQ3 C;  3SFE D;  2WDR D;  2H89 C;  3SFD C;  3AEA D;  3AEB C;  1KF6 C;  2B76 C;  1L0V C;  2ACZ D;  2WDQ C;  2WU2 D;  1ZP0 C;  3AE6 C;  2H89 D;  3SFD D;  3VRB C;  3VR9 D;  2WDV C;  3AED C;  2WU5 C;  1KF6 D;  1NEK D;  2B76 D;  1L0V D;  2FBW D;  3ABV C;  4KX6 D;  1ZP0 D;  3P4P C;  3AEG C;  3VRB D;  2WDV D;  1ZOY C;  3AED D;  1QLB C;  5C3J C;  1YQ4 D;  2WS3 C;  3P4S C;  3P4R C;  2WP9 C;  3AEF C;  1YQ3 D;  4YSY C;  3VRA C;  3P4P D;  3AEE C;  3AE9 C;  3AEG D;  1E7P C;  1ZOY D;  3AEB D;  3CIR C;  5C3J D;  2WS3 D;  4YTP C;  3P4R D;  2BS2 C;  2WP9 D;  5C2T C;  2WDQ D;  2BS3 C;  3AEF D;  3AE2 C;  4YTN C;  3AE3 C;  4YSY D;  4YTM C;  3AE6 D;  3AEE D;  3AE9 D;  3AE5 C;  3VR8 C;  3SFE C;  2WU5 D;  2WQY C;  4YSX C;  3AE1 C;  3AE7 C;  4YTP D;  3AEC C;  3ABV D;  5C2T D;  4YTN D;  2H88 C;  3AE2 D;  3AE3 D;  1KFY C;  3AE5 D;  2WQY D;  2WU2 C;  4YSX D;  3AE1 D;  4YT0 C;  3P4Q C;  3AE8 C;  1YQ4 C;  3AE7 D;  3P4S D;  3AEC D;  2BS4 C;  3VR9 C;  2H88 D;  3VRA D;  1NEK C;  1KFY D;  4YSZ C;  1NEN C;  3AE4 C;  2FBW C;  4YXD C;  4KX6 C;  2WDR C;  3CIR D;  4YT0 D;  3P4Q D;  3AE8 D;  3AEA C; 
#chains in the Genus database with same CATH topology
 4LDT A;  4YTM D;  4YSZ D;  2ACZ C;  1NEN D;  3AE4 D;  3VR8 D;  3VON A;  4YXD D;  1YQ3 C;  3SFE D;  2WDR D;  2H89 C;  3SFD C;  3AEA D;  3AEB C;  1KF6 C;  2B76 C;  1L0V C;  2ACZ D;  2WDQ C;  2WU2 D;  1ZP0 C;  3AE6 C;  2H89 D;  3SFD D;  3VRB C;  3VR9 D;  2WDV C;  3AED C;  2WU5 C;  1KF6 D;  1NEK D;  2B76 D;  1L0V D;  2FBW D;  3ABV C;  4KX6 D;  1ZP0 D;  2ZFY A;  3P4P C;  3AEG C;  3VRB D;  2WDV D;  1ZOY C;  3AED D;  1QLB C;  4DDI A;  4DHJ A;  5C3J C;  1YQ4 D;  2WS3 C;  3P4S C;  3P4R C;  2WP9 C;  3AEF C;  1YQ3 D;  4YSY C;  3VRA C;  3P4P D;  3AEE C;  3AE9 C;  3AEG D;  1E7P C;  1ZOY D;  3AEB D;  3CIR C;  4FJV A;  5C3J D;  2WS3 D;  4YTP C;  3P4R D;  2BS2 C;  2WP9 D;  5C2T C;  2WDQ D;  2BS3 C;  3AEF D;  3AE2 C;  4YTN C;  3AE3 C;  4YSY D;  4YTM C;  3AE6 D;  3AEE D;  3AE9 D;  3AE5 C;  3VR8 C;  3SFE C;  2WU5 D;  2WQY C;  4YSX C;  1TFF A;  3AE1 C;  3AE7 C;  4YTP D;  3AEC C;  3ABV D;  5C2T D;  4YTN D;  2H88 C;  3AE2 D;  3AE3 D;  1KFY C;  3AE5 D;  2WQY D;  2WU2 C;  4YSX D;  3AE1 D;  4YT0 C;  3P4Q C;  4DHZ A;  3AE8 C;  1YQ4 C;  3AE7 D;  3P4S D;  3AEC D;  2BS4 C;  3VR9 C;  2H88 D;  4DHI B;  3VRA D;  1NEK C;  1KFY D;  4YSZ C;  1NEN C;  3AE4 C;  2FBW C;  4I6L A;  4YXD C;  4KX6 C;  2WDR C;  3CIR D;  4DDG A;  4YT0 D;  3P4Q D;  3AE8 D;  3AEA C; 
#chains in the Genus database with same CATH homology
 4YTM D;  4YSZ D;  2ACZ C;  1NEN D;  3AE4 D;  3VR8 D;  4YXD D;  1YQ3 C;  3SFE D;  2WDR D;  2H89 C;  3SFD C;  3AEA D;  3AEB C;  1KF6 C;  2B76 C;  1L0V C;  2ACZ D;  2WDQ C;  2WU2 D;  1ZP0 C;  3AE6 C;  2H89 D;  3SFD D;  3VRB C;  3VR9 D;  2WDV C;  3AED C;  2WU5 C;  1KF6 D;  1NEK D;  2B76 D;  1L0V D;  2FBW D;  3ABV C;  4KX6 D;  1ZP0 D;  3P4P C;  3AEG C;  3VRB D;  2WDV D;  1ZOY C;  3AED D;  1QLB C;  5C3J C;  1YQ4 D;  2WS3 C;  3P4S C;  3P4R C;  2WP9 C;  3AEF C;  1YQ3 D;  4YSY C;  3VRA C;  3P4P D;  3AEE C;  3AE9 C;  3AEG D;  1E7P C;  1ZOY D;  3AEB D;  3CIR C;  5C3J D;  2WS3 D;  4YTP C;  3P4R D;  2BS2 C;  2WP9 D;  5C2T C;  2WDQ D;  2BS3 C;  3AEF D;  3AE2 C;  4YTN C;  3AE3 C;  4YSY D;  4YTM C;  3AE6 D;  3AEE D;  3AE9 D;  3AE5 C;  3VR8 C;  3SFE C;  2WU5 D;  2WQY C;  4YSX C;  3AE1 C;  3AE7 C;  4YTP D;  3AEC C;  3ABV D;  5C2T D;  4YTN D;  2H88 C;  3AE2 D;  3AE3 D;  1KFY C;  3AE5 D;  2WQY D;  2WU2 C;  4YSX D;  3AE1 D;  4YT0 C;  3P4Q C;  3AE8 C;  1YQ4 C;  3AE7 D;  3P4S D;  3AEC D;  2BS4 C;  3VR9 C;  2H88 D;  3VRA D;  1NEK C;  1KFY D;  4YSZ C;  1NEN C;  3AE4 C;  2FBW C;  4YXD C;  4KX6 C;  2WDR C;  3CIR D;  4YT0 D;  3P4Q D;  3AE8 D;  3AEA C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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