4YTND

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with n-[3-(pentafluorophenoxy)phenyl]-2-(trifluoromethyl)benzamide
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
129
structure length
129
Chain Sequence
TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title New Insights into the Design of Inhibitors Targeted for Parasitic Anaerobic Energy Metabolism
rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase flavoprotein
total genus 38
structure length 129
sequence length 129
chains with identical sequence H
ec nomenclature
pdb deposition date 2015-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05328 CybS CybS, succinate dehydrogenase cytochrome B small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 4ytnD00
3AE7D 3AECC 3AE8D 1ZOYC 3AEED 1KF6D 3VRBC 2WU5C 1L0VD 3P4PD 4YTND 1NEKC 3AE1D 3P4RC 4YSZC 3AE3C 5C2TC 4YXDC 3CIRD 1NEND 3P4QD 3AE2C 2B76D 2WDVD 4YTPC 1ZP0D 3ABVC 2H88C 2WU2D 4YTMC 3AE6C 3AEGC 3AEAD 2BS4C 3AEBD 1YQ3D 3AEEC 1QLBC 2WDQC 3P4PC 4YTNC 3AEDC 3AE1C 4YSYD 5C3JD 2WP9C 4YT0D 4KX6D 1KFYD 3AE4C 2WDRC 3AE5C 2WQYD 4YSXD 3VR9C 2BS2C 3AECD 1ZOYD 2WU2C 3VRBD 3SFEC 2WS3C 2FBWC 2WU5D 3AE9D 1YQ4D 3VRAC 3AEAC 1NEKD 3AEBC 3AE7C 3AE8C 1KF6C 3AEFD 4YSZD 3AE3D 3P4SD 5C2TD 1L0VC 3SFDD 3AE2D 5C3JC 2ACZD 3VR8D 3ABVD 1KFYC 2H88D 4YTMD 3CIRC 1NENC 3P4QC 2B76C 2WDVC 2H89D 1ZP0C 2WDQD 3AE9C 1YQ4C 2BS3C 3AEDD 1YQ3C 3P4RD 2WP9D 3AEFC 3P4SC 4YXDD 3AE4D 2WDRD 3AE5D 3SFDC 4YSYC 4YTPD 4YT0C 2ACZC 3VR8C 3VR9D 4KX6C 1E7PC 3AE6D 3SFED 2WS3D 2FBWD 2WQYC 3AEGD 2H89C 3VRAD 4YSXC
chains in the Genus database with same CATH superfamily
3AE7D 3AECC 3AE8D 1ZOYC 3AEED 4DDGA 1KF6D 3VRBC 2WU5C 1L0VD 3P4PD 4YTND 1NEKC 3AE1D 3P4RC 4YSZC 3AE3C 5C2TC 4YXDC 3CIRD 1NEND 3P4QD 3AE2C 2B76D 2WDVD 4YTPC 1ZP0D 3ABVC 2H88C 2WU2D 4YTMC 3AE6C 4DHIB 3AEGC 3AEAD 2BS4C 3AEBD 1YQ3D 3AEEC 1QLBC 2WDQC 3P4PC 4YTNC 3AEDC 3AE1C 4YSYD 5C3JD 2WP9C 4YT0D 4KX6D 1KFYD 4I6LA 3AE4C 4DDIA 2WDRC 3AE5C 2WQYD 4YSXD 3VR9C 2BS2C 3AECD 1ZOYD 2WU2C 3VRBD 3SFEC 2WS3C 2FBWC 2WU5D 3AE9D 1YQ4D 3VRAC 3AEAC 1NEKD 3AEBC 3AE7C 3AE8C 1KF6C 3AEFD 4YSZD 3AE3D 3P4SD 5C2TD 1L0VC 3SFDD 3AE2D 5C3JC 2ACZD 4DHZA 3VR8D 3ABVD 3VONA 1KFYC 2H88D 4YTMD 3CIRC 1NENC 3P4QC 2B76C 2WDVC 2H89D 1ZP0C 4LDTA 2WDQD 3AE9C 1YQ4C 2BS3C 4FJVA 3AEDD 1YQ3C 3P4RD 2WP9D 3AEFC 3P4SC 4YXDD 3AE4D 1TFFA 2WDRD 3AE5D 3SFDC 4YSYC 4DHJA 4YTPD 4YT0C 2ACZC 3VR8C 3VR9D 4KX6C 1E7PC 3AE6D 3SFED 2WS3D 2FBWD 2ZFYA 2WQYC 3AEGD 2H89C 3VRAD 4YSXC
chains in the Genus database with same CATH topology
3AE7D 3AECC 3AE8D 1ZOYC 3AEED 1KF6D 3VRBC 2WU5C 1L0VD 3P4PD 4YTND 1NEKC 3AE1D 3P4RC 4YSZC 3AE3C 5C2TC 4YXDC 3CIRD 1NEND 3P4QD 3AE2C 2B76D 2WDVD 4YTPC 1ZP0D 3ABVC 2H88C 2WU2D 4YTMC 3AE6C 3AEGC 3AEAD 2BS4C 3AEBD 1YQ3D 3AEEC 1QLBC 2WDQC 3P4PC 4YTNC 3AEDC 3AE1C 4YSYD 5C3JD 2WP9C 4YT0D 4KX6D 1KFYD 3AE4C 2WDRC 3AE5C 2WQYD 4YSXD 3VR9C 2BS2C 3AECD 1ZOYD 2WU2C 3VRBD 3SFEC 2WS3C 2FBWC 2WU5D 3AE9D 1YQ4D 3VRAC 3AEAC 1NEKD 3AEBC 3AE7C 3AE8C 1KF6C 3AEFD 4YSZD 3AE3D 3P4SD 5C2TD 1L0VC 3SFDD 3AE2D 5C3JC 2ACZD 3VR8D 3ABVD 1KFYC 2H88D 4YTMD 3CIRC 1NENC 3P4QC 2B76C 2WDVC 2H89D 1ZP0C 2WDQD 3AE9C 1YQ4C 2BS3C 3AEDD 1YQ3C 3P4RD 2WP9D 3AEFC 3P4SC 4YXDD 3AE4D 2WDRD 3AE5D 3SFDC 4YSYC 4YTPD 4YT0C 2ACZC 3VR8C 3VR9D 4KX6C 1E7PC 3AE6D 3SFED 2WS3D 2FBWD 2WQYC 3AEGD 2H89C 3VRAD 4YSXC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AE7 D;  3AEC C;  3AE8 D;  1ZOY C;  3AEE D;  1KF6 D;  3VRB C;  2WU5 C;  1L0V D;  3P4P D;  4YTN D;  1NEK C;  3AE1 D;  3P4R C;  4YSZ C;  3AE3 C;  5C2T C;  4YXD C;  3CIR D;  1NEN D;  3P4Q D;  3AE2 C;  2B76 D;  2WDV D;  4YTP C;  1ZP0 D;  3ABV C;  2H88 C;  2WU2 D;  4YTM C;  3AE6 C;  3AEG C;  3AEA D;  2BS4 C;  3AEB D;  1YQ3 D;  3AEE C;  1QLB C;  2WDQ C;  3P4P C;  4YTN C;  3AED C;  3AE1 C;  4YSY D;  5C3J D;  2WP9 C;  4YT0 D;  4KX6 D;  1KFY D;  3AE4 C;  2WDR C;  3AE5 C;  2WQY D;  4YSX D;  3VR9 C;  2BS2 C;  3AEC D;  1ZOY D;  2WU2 C;  3VRB D;  3SFE C;  2WS3 C;  2FBW C;  2WU5 D;  3AE9 D;  1YQ4 D;  3VRA C;  3AEA C;  1NEK D;  3AEB C;  3AE7 C;  3AE8 C;  1KF6 C;  3AEF D;  4YSZ D;  3AE3 D;  3P4S D;  5C2T D;  1L0V C;  3SFD D;  3AE2 D;  5C3J C;  2ACZ D;  3VR8 D;  3ABV D;  1KFY C;  2H88 D;  4YTM D;  3CIR C;  1NEN C;  3P4Q C;  2B76 C;  2WDV C;  2H89 D;  1ZP0 C;  2WDQ D;  3AE9 C;  1YQ4 C;  2BS3 C;  3AED D;  1YQ3 C;  3P4R D;  2WP9 D;  3AEF C;  3P4S C;  4YXD D;  3AE4 D;  2WDR D;  3AE5 D;  3SFD C;  4YSY C;  4YTP D;  4YT0 C;  2ACZ C;  3VR8 C;  3VR9 D;  4KX6 C;  1E7P C;  3AE6 D;  3SFE D;  2WS3 D;  2FBW D;  2WQY C;  3AEG D;  2H89 C;  3VRA D;  4YSX C; 
#chains in the Genus database with same CATH topology
 3AE7 D;  3AEC C;  3AE8 D;  1ZOY C;  3AEE D;  4DDG A;  1KF6 D;  3VRB C;  2WU5 C;  1L0V D;  3P4P D;  4YTN D;  1NEK C;  3AE1 D;  3P4R C;  4YSZ C;  3AE3 C;  5C2T C;  4YXD C;  3CIR D;  1NEN D;  3P4Q D;  3AE2 C;  2B76 D;  2WDV D;  4YTP C;  1ZP0 D;  3ABV C;  2H88 C;  2WU2 D;  4YTM C;  3AE6 C;  4DHI B;  3AEG C;  3AEA D;  2BS4 C;  3AEB D;  1YQ3 D;  3AEE C;  1QLB C;  2WDQ C;  3P4P C;  4YTN C;  3AED C;  3AE1 C;  4YSY D;  5C3J D;  2WP9 C;  4YT0 D;  4KX6 D;  1KFY D;  4I6L A;  3AE4 C;  4DDI A;  2WDR C;  3AE5 C;  2WQY D;  4YSX D;  3VR9 C;  2BS2 C;  3AEC D;  1ZOY D;  2WU2 C;  3VRB D;  3SFE C;  2WS3 C;  2FBW C;  2WU5 D;  3AE9 D;  1YQ4 D;  3VRA C;  3AEA C;  1NEK D;  3AEB C;  3AE7 C;  3AE8 C;  1KF6 C;  3AEF D;  4YSZ D;  3AE3 D;  3P4S D;  5C2T D;  1L0V C;  3SFD D;  3AE2 D;  5C3J C;  2ACZ D;  4DHZ A;  3VR8 D;  3ABV D;  3VON A;  1KFY C;  2H88 D;  4YTM D;  3CIR C;  1NEN C;  3P4Q C;  2B76 C;  2WDV C;  2H89 D;  1ZP0 C;  4LDT A;  2WDQ D;  3AE9 C;  1YQ4 C;  2BS3 C;  4FJV A;  3AED D;  1YQ3 C;  3P4R D;  2WP9 D;  3AEF C;  3P4S C;  4YXD D;  3AE4 D;  1TFF A;  2WDR D;  3AE5 D;  3SFD C;  4YSY C;  4DHJ A;  4YTP D;  4YT0 C;  2ACZ C;  3VR8 C;  3VR9 D;  4KX6 C;  1E7P C;  3AE6 D;  3SFE D;  2WS3 D;  2FBW D;  2ZFY A;  2WQY C;  3AEG D;  2H89 C;  3VRA D;  4YSX C; 
#chains in the Genus database with same CATH homology
 3AE7 D;  3AEC C;  3AE8 D;  1ZOY C;  3AEE D;  1KF6 D;  3VRB C;  2WU5 C;  1L0V D;  3P4P D;  4YTN D;  1NEK C;  3AE1 D;  3P4R C;  4YSZ C;  3AE3 C;  5C2T C;  4YXD C;  3CIR D;  1NEN D;  3P4Q D;  3AE2 C;  2B76 D;  2WDV D;  4YTP C;  1ZP0 D;  3ABV C;  2H88 C;  2WU2 D;  4YTM C;  3AE6 C;  3AEG C;  3AEA D;  2BS4 C;  3AEB D;  1YQ3 D;  3AEE C;  1QLB C;  2WDQ C;  3P4P C;  4YTN C;  3AED C;  3AE1 C;  4YSY D;  5C3J D;  2WP9 C;  4YT0 D;  4KX6 D;  1KFY D;  3AE4 C;  2WDR C;  3AE5 C;  2WQY D;  4YSX D;  3VR9 C;  2BS2 C;  3AEC D;  1ZOY D;  2WU2 C;  3VRB D;  3SFE C;  2WS3 C;  2FBW C;  2WU5 D;  3AE9 D;  1YQ4 D;  3VRA C;  3AEA C;  1NEK D;  3AEB C;  3AE7 C;  3AE8 C;  1KF6 C;  3AEF D;  4YSZ D;  3AE3 D;  3P4S D;  5C2T D;  1L0V C;  3SFD D;  3AE2 D;  5C3J C;  2ACZ D;  3VR8 D;  3ABV D;  1KFY C;  2H88 D;  4YTM D;  3CIR C;  1NEN C;  3P4Q C;  2B76 C;  2WDV C;  2H89 D;  1ZP0 C;  2WDQ D;  3AE9 C;  1YQ4 C;  2BS3 C;  3AED D;  1YQ3 C;  3P4R D;  2WP9 D;  3AEF C;  3P4S C;  4YXD D;  3AE4 D;  2WDR D;  3AE5 D;  3SFD C;  4YSY C;  4YTP D;  4YT0 C;  2ACZ C;  3VR8 C;  3VR9 D;  4KX6 C;  1E7P C;  3AE6 D;  3SFE D;  2WS3 D;  2FBW D;  2WQY C;  3AEG D;  2H89 C;  3VRA D;  4YSX C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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