4YTPD

Crystal structure of porcine heart mitochondrial complex ii bound with n-[(4-tert-butylphenyl)methyl]-2-(trifluoromethyl)benzamide
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
102
structure length
102
Chain Sequence
SSKAASLHWTGERVVSVLLLGLLPAAYLNPCSAMDYSLAAALTLHGHWGIGQVVTDYVRGDALQKVAKAGLLALSAFTFAGLCYFNYHDVGICKAVAMLWKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase [ubiquinone] flavoprotein subunit, m
total genus 42
structure length 102
sequence length 102
ec nomenclature
pdb deposition date 2015-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05328 CybS CybS, succinate dehydrogenase cytochrome B small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 4ytpD00
3AE9C 2WU2C 3VR9C 4YXDC 3AEAD 5C2TC 3AEDC 2ACZD 3AEFC 3SFEC 3AE8D 2ACZC 2WU5C 3CIRC 2WQYD 4YTPD 1NEND 3AE8C 1ZOYD 2H89D 4YSYD 4YSXD 3P4SD 2WDRC 3AEBD 3AE5D 2WQYC 3AE2D 4YSXC 2H89C 4YSZC 4YSYC 3VRAD 3P4SC 1KF6C 4YT0D 3AE5C 3AEBC 1QLBC 2WS3D 2WDQD 3VRAC 1YQ3C 2B76D 4YT0C 2WDQC 3P4PC 4YTMD 1E7PC 1NEKD 3AEAC 3SFDD 3AECD 3AEGD 3AE3D 2BS3C 3AE7D 3SFDC 2H88D 3AE3C 3VR8D 4YTPC 2BS4C 1NENC 1ZOYC 1ZP0D 3VR8C 3AE1D 3AE2C 1ZP0C 3AE1C 2WP9D 2WS3C 2B76C 1YQ4D 3AE6D 2WP9C 5C3JD 4KX6D 3AE4D 2WDVD 4YTND 3P4RD 4YTMC 1NEKC 4KX6C 2BS2C 3AE4C 2FBWD 3ABVD 3AECC 3AEGC 3P4RC 3AEED 3AE7C 2WU2D 3VR9D 4YXDD 5C2TD 2H88C 3AEEC 3SFED 1L0VD 3CIRD 2WU5D 3P4QD 1L0VC 3VRBD 3P4QC 1KFYD 2WDRD 4YSZD 1YQ4C 3AE6C 3VRBC 1KFYC 1KF6D 5C3JC 1YQ3D 2WDVC 4YTNC 3AE9D 2FBWC 3P4PD 3ABVC 3AEDD 3AEFD
chains in the Genus database with same CATH superfamily
3AE9C 2WU2C 3VR9C 4YXDC 3AEAD 5C2TC 3AEDC 2ACZD 4DHIB 3AEFC 3SFEC 3AE8D 2ACZC 2WU5C 3CIRC 2WQYD 4YTPD 1NEND 3AE8C 1ZOYD 2H89D 4YSYD 4YSXD 3P4SD 2WDRC 3AEBD 3AE5D 2WQYC 3AE2D 4YSXC 2H89C 4YSZC 4YSYC 3VRAD 3P4SC 1KF6C 4YT0D 3AE5C 3AEBC 1QLBC 2WS3D 3VONA 2WDQD 4DDGA 3VRAC 1YQ3C 4LDTA 2B76D 4YT0C 2ZFYA 2WDQC 3P4PC 4YTMD 4DDIA 1E7PC 1NEKD 3AEAC 3SFDD 3AECD 3AEGD 3AE3D 2BS3C 3AE7D 3SFDC 2H88D 3AE3C 3VR8D 4YTPC 2BS4C 1NENC 1ZOYC 1ZP0D 3VR8C 3AE1D 3AE2C 1ZP0C 1TFFA 3AE1C 2WP9D 2WS3C 2B76C 1YQ4D 3AE6D 2WP9C 5C3JD 4KX6D 3AE4D 2WDVD 4YTND 3P4RD 4YTMC 1NEKC 4KX6C 2BS2C 3AE4C 2FBWD 3ABVD 3AECC 3AEGC 3P4RC 4DHJA 3AEED 3AE7C 2WU2D 3VR9D 4YXDD 5C2TD 2H88C 3AEEC 3SFED 1L0VD 3CIRD 2WU5D 3P4QD 1L0VC 3VRBD 3P4QC 1KFYD 2WDRD 4YSZD 1YQ4C 3AE6C 3VRBC 4DHZA 1KFYC 1KF6D 5C3JC 1YQ3D 2WDVC 4YTNC 4I6LA 3AE9D 2FBWC 4FJVA 3P4PD 3ABVC 3AEDD 3AEFD
chains in the Genus database with same CATH topology
3AE9C 2WU2C 3VR9C 4YXDC 3AEAD 5C2TC 3AEDC 2ACZD 3AEFC 3SFEC 3AE8D 2ACZC 2WU5C 3CIRC 2WQYD 4YTPD 1NEND 3AE8C 1ZOYD 2H89D 4YSYD 4YSXD 3P4SD 2WDRC 3AEBD 3AE5D 2WQYC 3AE2D 4YSXC 2H89C 4YSZC 4YSYC 3VRAD 3P4SC 1KF6C 4YT0D 3AE5C 3AEBC 1QLBC 2WS3D 2WDQD 3VRAC 1YQ3C 2B76D 4YT0C 2WDQC 3P4PC 4YTMD 1E7PC 1NEKD 3AEAC 3SFDD 3AECD 3AEGD 3AE3D 2BS3C 3AE7D 3SFDC 2H88D 3AE3C 3VR8D 4YTPC 2BS4C 1NENC 1ZOYC 1ZP0D 3VR8C 3AE1D 3AE2C 1ZP0C 3AE1C 2WP9D 2WS3C 2B76C 1YQ4D 3AE6D 2WP9C 5C3JD 4KX6D 3AE4D 2WDVD 4YTND 3P4RD 4YTMC 1NEKC 4KX6C 2BS2C 3AE4C 2FBWD 3ABVD 3AECC 3AEGC 3P4RC 3AEED 3AE7C 2WU2D 3VR9D 4YXDD 5C2TD 2H88C 3AEEC 3SFED 1L0VD 3CIRD 2WU5D 3P4QD 1L0VC 3VRBD 3P4QC 1KFYD 2WDRD 4YSZD 1YQ4C 3AE6C 3VRBC 1KFYC 1KF6D 5C3JC 1YQ3D 2WDVC 4YTNC 3AE9D 2FBWC 3P4PD 3ABVC 3AEDD 3AEFD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AE9 C;  2WU2 C;  3VR9 C;  4YXD C;  3AEA D;  5C2T C;  3AED C;  2ACZ D;  3AEF C;  3SFE C;  3AE8 D;  2ACZ C;  2WU5 C;  3CIR C;  2WQY D;  4YTP D;  1NEN D;  3AE8 C;  1ZOY D;  2H89 D;  4YSY D;  4YSX D;  3P4S D;  2WDR C;  3AEB D;  3AE5 D;  2WQY C;  3AE2 D;  4YSX C;  2H89 C;  4YSZ C;  4YSY C;  3VRA D;  3P4S C;  1KF6 C;  4YT0 D;  3AE5 C;  3AEB C;  1QLB C;  2WS3 D;  2WDQ D;  3VRA C;  1YQ3 C;  2B76 D;  4YT0 C;  2WDQ C;  3P4P C;  4YTM D;  1E7P C;  1NEK D;  3AEA C;  3SFD D;  3AEC D;  3AEG D;  3AE3 D;  2BS3 C;  3AE7 D;  3SFD C;  2H88 D;  3AE3 C;  3VR8 D;  4YTP C;  2BS4 C;  1NEN C;  1ZOY C;  1ZP0 D;  3VR8 C;  3AE1 D;  3AE2 C;  1ZP0 C;  3AE1 C;  2WP9 D;  2WS3 C;  2B76 C;  1YQ4 D;  3AE6 D;  2WP9 C;  5C3J D;  4KX6 D;  3AE4 D;  2WDV D;  4YTN D;  3P4R D;  4YTM C;  1NEK C;  4KX6 C;  2BS2 C;  3AE4 C;  2FBW D;  3ABV D;  3AEC C;  3AEG C;  3P4R C;  3AEE D;  3AE7 C;  2WU2 D;  3VR9 D;  4YXD D;  5C2T D;  2H88 C;  3AEE C;  3SFE D;  1L0V D;  3CIR D;  2WU5 D;  3P4Q D;  1L0V C;  3VRB D;  3P4Q C;  1KFY D;  2WDR D;  4YSZ D;  1YQ4 C;  3AE6 C;  3VRB C;  1KFY C;  1KF6 D;  5C3J C;  1YQ3 D;  2WDV C;  4YTN C;  3AE9 D;  2FBW C;  3P4P D;  3ABV C;  3AED D;  3AEF D; 
#chains in the Genus database with same CATH topology
 3AE9 C;  2WU2 C;  3VR9 C;  4YXD C;  3AEA D;  5C2T C;  3AED C;  2ACZ D;  4DHI B;  3AEF C;  3SFE C;  3AE8 D;  2ACZ C;  2WU5 C;  3CIR C;  2WQY D;  4YTP D;  1NEN D;  3AE8 C;  1ZOY D;  2H89 D;  4YSY D;  4YSX D;  3P4S D;  2WDR C;  3AEB D;  3AE5 D;  2WQY C;  3AE2 D;  4YSX C;  2H89 C;  4YSZ C;  4YSY C;  3VRA D;  3P4S C;  1KF6 C;  4YT0 D;  3AE5 C;  3AEB C;  1QLB C;  2WS3 D;  3VON A;  2WDQ D;  4DDG A;  3VRA C;  1YQ3 C;  4LDT A;  2B76 D;  4YT0 C;  2ZFY A;  2WDQ C;  3P4P C;  4YTM D;  4DDI A;  1E7P C;  1NEK D;  3AEA C;  3SFD D;  3AEC D;  3AEG D;  3AE3 D;  2BS3 C;  3AE7 D;  3SFD C;  2H88 D;  3AE3 C;  3VR8 D;  4YTP C;  2BS4 C;  1NEN C;  1ZOY C;  1ZP0 D;  3VR8 C;  3AE1 D;  3AE2 C;  1ZP0 C;  1TFF A;  3AE1 C;  2WP9 D;  2WS3 C;  2B76 C;  1YQ4 D;  3AE6 D;  2WP9 C;  5C3J D;  4KX6 D;  3AE4 D;  2WDV D;  4YTN D;  3P4R D;  4YTM C;  1NEK C;  4KX6 C;  2BS2 C;  3AE4 C;  2FBW D;  3ABV D;  3AEC C;  3AEG C;  3P4R C;  4DHJ A;  3AEE D;  3AE7 C;  2WU2 D;  3VR9 D;  4YXD D;  5C2T D;  2H88 C;  3AEE C;  3SFE D;  1L0V D;  3CIR D;  2WU5 D;  3P4Q D;  1L0V C;  3VRB D;  3P4Q C;  1KFY D;  2WDR D;  4YSZ D;  1YQ4 C;  3AE6 C;  3VRB C;  4DHZ A;  1KFY C;  1KF6 D;  5C3J C;  1YQ3 D;  2WDV C;  4YTN C;  4I6L A;  3AE9 D;  2FBW C;  4FJV A;  3P4P D;  3ABV C;  3AED D;  3AEF D; 
#chains in the Genus database with same CATH homology
 3AE9 C;  2WU2 C;  3VR9 C;  4YXD C;  3AEA D;  5C2T C;  3AED C;  2ACZ D;  3AEF C;  3SFE C;  3AE8 D;  2ACZ C;  2WU5 C;  3CIR C;  2WQY D;  4YTP D;  1NEN D;  3AE8 C;  1ZOY D;  2H89 D;  4YSY D;  4YSX D;  3P4S D;  2WDR C;  3AEB D;  3AE5 D;  2WQY C;  3AE2 D;  4YSX C;  2H89 C;  4YSZ C;  4YSY C;  3VRA D;  3P4S C;  1KF6 C;  4YT0 D;  3AE5 C;  3AEB C;  1QLB C;  2WS3 D;  2WDQ D;  3VRA C;  1YQ3 C;  2B76 D;  4YT0 C;  2WDQ C;  3P4P C;  4YTM D;  1E7P C;  1NEK D;  3AEA C;  3SFD D;  3AEC D;  3AEG D;  3AE3 D;  2BS3 C;  3AE7 D;  3SFD C;  2H88 D;  3AE3 C;  3VR8 D;  4YTP C;  2BS4 C;  1NEN C;  1ZOY C;  1ZP0 D;  3VR8 C;  3AE1 D;  3AE2 C;  1ZP0 C;  3AE1 C;  2WP9 D;  2WS3 C;  2B76 C;  1YQ4 D;  3AE6 D;  2WP9 C;  5C3J D;  4KX6 D;  3AE4 D;  2WDV D;  4YTN D;  3P4R D;  4YTM C;  1NEK C;  4KX6 C;  2BS2 C;  3AE4 C;  2FBW D;  3ABV D;  3AEC C;  3AEG C;  3P4R C;  3AEE D;  3AE7 C;  2WU2 D;  3VR9 D;  4YXD D;  5C2T D;  2H88 C;  3AEE C;  3SFE D;  1L0V D;  3CIR D;  2WU5 D;  3P4Q D;  1L0V C;  3VRB D;  3P4Q C;  1KFY D;  2WDR D;  4YSZ D;  1YQ4 C;  3AE6 C;  3VRB C;  1KFY C;  1KF6 D;  5C3J C;  1YQ3 D;  2WDV C;  4YTN C;  3AE9 D;  2FBW C;  3P4P D;  3ABV C;  3AED D;  3AEF D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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