4YUBA

Crystal structure of human nicotinic acid phosphoribosyltransferase
Total Genus 130
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
130
sequence length
518
structure length
500
Chain Sequence
LLTDLYQATMALGYWRAGRARDAAEFELFFRRCPFGGAFALAAGLRDCVRFLRAFRLRDADVQFLASVLPPDTDPAFFEHLRALDCSEVTVRALPEGSLAFPGVPLLQVSGPLLVVQLLETPLLCLVSYASLVATNAARLRLIAGPEKRLLEMGLRRAQGPDGGLTASTYSYLGGFDSSSNVLAGQLRGVPVAGTLAHSFVTSFSGSEVPPDPMLAPAAGEGPGVDLAAKAQVWLEQVCAHLGLGVQEPHPGERAAFVAYALAFPRAFQGLLDTYSVWRSGLPNFLAVALALGELGYRAVGVRLDSGDLLQQAQEIRKVFRAAAAQFQVPWLESVLIVVSNNIDEEALARLAQEGSEVNVIGISLGGVYKLVAVGGQPRMKLTLPGSKAAFRLLGSDGSPLMDMLQLAEEPVPQAGQELRVWPPGAQEPCTVRPAQVEPLLRLCLQQGQLCEPLPSLAESRALAQLSLSRLSPEHRRLRSPAQYQVVLSERLQALVNSLC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ligase
molecule keywords Nicotinate phosphoribosyltransferase
publication title Crystal structure of human nicotinic acid phosphoribosyltransferase.
pubmed doi rcsb
source organism Homo sapiens
total genus 130
structure length 500
sequence length 518
chains with identical sequence B
ec nomenclature ec 6.3.4.21: Nicotinate phosphoribosyltransferase.
pdb deposition date 2015-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF17767 NAPRTase_N Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain
A PF17956 NAPRTase_C Nicotinate phosphoribosyltransferase C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.140.10 Alpha Beta Alpha-Beta Barrel nicotinate phosphoribosyltransferase nicotinate phosphoribosyltransferase 4yubA01
2IM5A 4YUBA 1YIRA 2F7FA 3OS4A 4HL7A 4MZYA 1VLPA 1YBEA
chains in the Genus database with same CATH superfamily
2IM5A 4YUBA 1YIRA 2F7FA 3OS4A 4HL7A 4MZYA 1VLPA 1YBEA
chains in the Genus database with same CATH topology
2IM5A 4YUBA 1YIRA 2F7FA 3OS4A 4HL7A 4MZYA 1VLPA 1YBEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IM5 A;  4YUB A;  1YIR A;  2F7F A;  3OS4 A;  4HL7 A;  4MZY A;  1VLP A;  1YBE A; 
#chains in the Genus database with same CATH topology
 2IM5 A;  4YUB A;  1YIR A;  2F7F A;  3OS4 A;  4HL7 A;  4MZY A;  1VLP A;  1YBE A; 
#chains in the Genus database with same CATH homology
 2IM5 A;  4YUB A;  1YIR A;  2F7F A;  3OS4 A;  4HL7 A;  4MZY A;  1VLP A;  1YBE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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