4YVJA

Crystal structure of h. influenzae trmd in complex with sinefungin and trna variant (g36u)
Total Genus 68
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
Knots found
sequence length
248
structure length
239
Chain Sequence
SHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVDSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.
pubmed doi rcsb
molecule tags Transferase/rna
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 68
structure length 239
sequence length 248
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yvjA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yvjA01
4FAKA 2QWVA 4YQCA 4YPXA 1P9PA 4JALA 4YQOA 4RG1A 4YVKA 1O6DA 1VH0A 3KNUA 3BBEA 4E8BA 1V2XA 5GM8A 3OINA 2I6DA 2V3KA 4YQ2A 4YVIA 4YQ1A 3ONPA 2HA8A 1IPAA 4YPWA 4YQAA 2Z0YA 3AIAA 1VHKA 4MCDA 3AXZA 4MCCA 2EGVA 5D9FA 5GMCA 1TO0A 4YQPA 4H3ZA 4YQ6A 3OIIA 4YQSA 4YQLA 4J3CA 1J85A 4YQ9A 3DCMX 4L69A 4KDZA 4YQ3A 3N4KA 1MXIA 3BBHA 2QMMA 4YQNA 1X7PA 4YVJA 3N4JA 4YPZA 1UAMA 1UAJA 3NK6A 4YQ5A 3L8UA 3OIJA 1V6ZA 1VHYA 4H3YA 4YQ0A 3KW2A 3KY7A 4CNFA 3AI9X 3O7BA 4YQGA 1GZ0A 3BBDA 4MCBA 4X3MA 1K3RA 4YPYA 1UAKA 5FAIA 4X3LA 1NS5A 4YQQA 4YQRA 5GMBA 1ZJRA 2EGWA 3IC6A 3ILKA 4YQ8A 4KGNA 4XBOA 4YQJA 4CNDA 4IG6A 1UALA 4YVGA 2YY8A 1NXZA 4CNGA 3E5YA 4YQBA 3GYQA 2CX8A 4YQ4A 4CNEA 3IEFA 3QUVA 4JAKA 1X7OA 5CO4A 3NK7A 2V3JA 4YVHA 4YQKA 1OY5A 4YQ7A 1Z85A 2O3AA 4YQTA 4PZKA 3KTYA 4YQIA 4YQDA
chains in the Genus database with same CATH superfamily
4FAKA 2QWVA 4YQCA 4YPXA 3SSXN 1P9PA 4JALA 4YQOA 4RG1A 4YVKA 1O6DA 3SSWN 1VH0A 3KNUA 3BBEA 4E8BA 1V2XA 5GM8A 3OINA 1TRRA 2I6DA 2V3KA 4YQ2A 4YVIA 1RCSA 4YQ1A 1CO0A 3ONPA 2HA8A 1IPAA 1TROA 4YPWA 4YQAA 2Z0YA 3AIAA 1VHKA 4MCDA 3AXZA 4MCCA 2EGVA 5D9FA 5GMCA 1TO0A 4YQPA 4H3ZA 4YQ6A 3OIIA 4YQSA 4YQLA 4J3CA 1J85A 4YQ9A 3DCMX 4L69A 4KDZA 4YQ3A 3N4KA 1MXIA 3BBHA 2QMMA 4YQNA 1X7PA 4YVJA 1WRTR 1WRPR 3N4JA 4YPZA 1UAMA 1UAJA 3NK6A 4YQ5A 3L8UA 3OIJA 1V6ZA 1VHYA 1JHGA 4H3YA 3WRPA 1MI7R 4YQ0A 3KW2A 3KY7A 4CNFA 3AI9X 3O7BA 4YQGA 4JWFA 1GZ0A 1WRSR 4MCBA 3BBDA 4X3MA 1K3RA 4YPYA 1UAKA 5FAIA 2OZ9R 4X3LA 1NS5A 3G1CA 4YQQA 4YQRA 5GMBA 4JWJA 1ZJRA 2EGWA 3IC6A 3ILKA 4YQ8A 4KGNA 4XBOA 4JWHA 4YQJA 4CNDA 4IG6A 4FMWA 1UALA 4YVGA 2YY8A 1ZT9A 1NXZA 4CNGA 3E5YA 4JWGA 4YQBA 3GYQA 2CX8A 4YQ4A 4CNEA 3IEFA 3QUVA 4JAKA 1X7OA 5CO4A 3NK7A 2XDIA 2V3JA 4YVHA 4YQKA 1OY5A 4YQ7A 3FRWA 1Z85A 2O3AA 3KORA 4YQTA 4PZKA 3KTYA 4YQIA 4YQDA
chains in the Genus database with same CATH topology
4FAKA 2QWVA 4YQCA 4YPXA 1P9PA 4JALA 4YQOA 4RG1A 4YVKA 1O6DA 1VH0A 3KNUA 3BBEA 4E8BA 1V2XA 5GM8A 3OINA 2I6DA 2V3KA 4YQ2A 4YVIA 4YQ1A 3ONPA 2HA8A 1IPAA 4YPWA 4YQAA 2Z0YA 3AIAA 1VHKA 4MCDA 3AXZA 4MCCA 2EGVA 5D9FA 5GMCA 1TO0A 4YQPA 4H3ZA 4YQ6A 3OIIA 4YQSA 4YQLA 4J3CA 1J85A 4YQ9A 3DCMX 4L69A 4KDZA 4YQ3A 3N4KA 1MXIA 3BBHA 2QMMA 4YQNA 1X7PA 4YVJA 3N4JA 4YPZA 1UAMA 1UAJA 3NK6A 4YQ5A 3L8UA 3OIJA 1V6ZA 1VHYA 4H3YA 4YQ0A 3KW2A 3KY7A 4CNFA 3AI9X 3O7BA 4YQGA 4JWFA 1GZ0A 3BBDA 4MCBA 4X3MA 1K3RA 4YPYA 1UAKA 5FAIA 4X3LA 1NS5A 4YQQA 4YQRA 5GMBA 4JWJA 1ZJRA 2EGWA 3IC6A 3ILKA 4YQ8A 4KGNA 4XBOA 4JWHA 4YQJA 4CNDA 4IG6A 4FMWA 1UALA 4YVGA 2YY8A 1NXZA 4CNGA 3E5YA 4JWGA 4YQBA 3GYQA 2CX8A 4YQ4A 4CNEA 3IEFA 3QUVA 4JAKA 1X7OA 5CO4A 3NK7A 2V3JA 4YVHA 4YQKA 1OY5A 4YQ7A 1Z85A 2O3AA 4YQTA 4PZKA 3KTYA 4YQIA 4YQDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FAK A;  2QWV A;  4YQC A;  4YPX A;  1P9P A;  4JAL A;  4YQO A;  4RG1 A;  4YVK A;  1O6D A;  1VH0 A;  3KNU A;  3BBE A;  4E8B A;  1V2X A;  5GM8 A;  3OIN A;  2I6D A;  2V3K A;  4YQ2 A;  4YVI A;  4YQ1 A;  3ONP A;  2HA8 A;  1IPA A;  4YPW A;  4YQA A;  2Z0Y A;  3AIA A;  1VHK A;  4MCD A;  3AXZ A;  4MCC A;  2EGV A;  5D9F A;  5GMC A;  1TO0 A;  4YQP A;  4H3Z A;  4YQ6 A;  3OII A;  4YQS A;  4YQL A;  4J3C A;  1J85 A;  4YQ9 A;  3DCM X;  4L69 A;  4KDZ A;  4YQ3 A;  3N4K A;  1MXI A;  3BBH A;  2QMM A;  4YQN A;  1X7P A;  4YVJ A;  3N4J A;  4YPZ A;  1UAM A;  1UAJ A;  3NK6 A;  4YQ5 A;  3L8U A;  3OIJ A;  1V6Z A;  1VHY A;  4H3Y A;  4YQ0 A;  3KW2 A;  3KY7 A;  4CNF A;  3AI9 X;  3O7B A;  4YQG A;  1GZ0 A;  3BBD A;  4MCB A;  4X3M A;  1K3R A;  4YPY A;  1UAK A;  5FAI A;  4X3L A;  1NS5 A;  4YQQ A;  4YQR A;  5GMB A;  1ZJR A;  2EGW A;  3IC6 A;  3ILK A;  4YQ8 A;  4KGN A;  4XBO A;  4YQJ A;  4CND A;  4IG6 A;  1UAL A;  4YVG A;  2YY8 A;  1NXZ A;  4CNG A;  3E5Y A;  4YQB A;  3GYQ A;  2CX8 A;  4YQ4 A;  4CNE A;  3IEF A;  3QUV A;  4JAK A;  1X7O A;  5CO4 A;  3NK7 A;  2V3J A;  4YVH A;  4YQK A;  1OY5 A;  4YQ7 A;  1Z85 A;  2O3A A;  4YQT A;  4PZK A;  3KTY A;  4YQI A;  4YQD A; 
#chains in the Genus database with same CATH topology
 4FAK A;  2QWV A;  4YQC A;  4YPX A;  3SSX N;  1P9P A;  4JAL A;  4YQO A;  4RG1 A;  4YVK A;  1O6D A;  3SSW N;  1VH0 A;  3KNU A;  3BBE A;  4E8B A;  1V2X A;  5GM8 A;  3OIN A;  1TRR A;  2I6D A;  2V3K A;  4YQ2 A;  4YVI A;  1RCS A;  4YQ1 A;  1CO0 A;  3ONP A;  2HA8 A;  1IPA A;  1TRO A;  4YPW A;  4YQA A;  2Z0Y A;  3AIA A;  1VHK A;  4MCD A;  3AXZ A;  4MCC A;  2EGV A;  5D9F A;  5GMC A;  1TO0 A;  4YQP A;  4H3Z A;  4YQ6 A;  3OII A;  4YQS A;  4YQL A;  4J3C A;  1J85 A;  4YQ9 A;  3DCM X;  4L69 A;  4KDZ A;  4YQ3 A;  3N4K A;  1MXI A;  3BBH A;  2QMM A;  4YQN A;  1X7P A;  4YVJ A;  1WRT R;  1WRP R;  3N4J A;  4YPZ A;  1UAM A;  1UAJ A;  3NK6 A;  4YQ5 A;  3L8U A;  3OIJ A;  1V6Z A;  1VHY A;  1JHG A;  4H3Y A;  3WRP A;  1MI7 R;  4YQ0 A;  3KW2 A;  3KY7 A;  4CNF A;  3AI9 X;  3O7B A;  4YQG A;  4JWF A;  1GZ0 A;  1WRS R;  4MCB A;  3BBD A;  4X3M A;  1K3R A;  4YPY A;  1UAK A;  5FAI A;  2OZ9 R;  4X3L A;  1NS5 A;  3G1C A;  4YQQ A;  4YQR A;  5GMB A;  4JWJ A;  1ZJR A;  2EGW A;  3IC6 A;  3ILK A;  4YQ8 A;  4KGN A;  4XBO A;  4JWH A;  4YQJ A;  4CND A;  4IG6 A;  4FMW A;  1UAL A;  4YVG A;  2YY8 A;  1ZT9 A;  1NXZ A;  4CNG A;  3E5Y A;  4JWG A;  4YQB A;  3GYQ A;  2CX8 A;  4YQ4 A;  4CNE A;  3IEF A;  3QUV A;  4JAK A;  1X7O A;  5CO4 A;  3NK7 A;  2XDI A;  2V3J A;  4YVH A;  4YQK A;  1OY5 A;  4YQ7 A;  3FRW A;  1Z85 A;  2O3A A;  3KOR A;  4YQT A;  4PZK A;  3KTY A;  4YQI A;  4YQD A; 
#chains in the Genus database with same CATH homology
 4FAK A;  2QWV A;  4YQC A;  4YPX A;  1P9P A;  4JAL A;  4YQO A;  4RG1 A;  4YVK A;  1O6D A;  1VH0 A;  3KNU A;  3BBE A;  4E8B A;  1V2X A;  5GM8 A;  3OIN A;  2I6D A;  2V3K A;  4YQ2 A;  4YVI A;  4YQ1 A;  3ONP A;  2HA8 A;  1IPA A;  4YPW A;  4YQA A;  2Z0Y A;  3AIA A;  1VHK A;  4MCD A;  3AXZ A;  4MCC A;  2EGV A;  5D9F A;  5GMC A;  1TO0 A;  4YQP A;  4H3Z A;  4YQ6 A;  3OII A;  4YQS A;  4YQL A;  4J3C A;  1J85 A;  4YQ9 A;  3DCM X;  4L69 A;  4KDZ A;  4YQ3 A;  3N4K A;  1MXI A;  3BBH A;  2QMM A;  4YQN A;  1X7P A;  4YVJ A;  3N4J A;  4YPZ A;  1UAM A;  1UAJ A;  3NK6 A;  4YQ5 A;  3L8U A;  3OIJ A;  1V6Z A;  1VHY A;  4H3Y A;  4YQ0 A;  3KW2 A;  3KY7 A;  4CNF A;  3AI9 X;  3O7B A;  4YQG A;  4JWF A;  1GZ0 A;  3BBD A;  4MCB A;  4X3M A;  1K3R A;  4YPY A;  1UAK A;  5FAI A;  4X3L A;  1NS5 A;  4YQQ A;  4YQR A;  5GMB A;  4JWJ A;  1ZJR A;  2EGW A;  3IC6 A;  3ILK A;  4YQ8 A;  4KGN A;  4XBO A;  4JWH A;  4YQJ A;  4CND A;  4IG6 A;  4FMW A;  1UAL A;  4YVG A;  2YY8 A;  1NXZ A;  4CNG A;  3E5Y A;  4JWG A;  4YQB A;  3GYQ A;  2CX8 A;  4YQ4 A;  4CNE A;  3IEF A;  3QUV A;  4JAK A;  1X7O A;  5CO4 A;  3NK7 A;  2V3J A;  4YVH A;  4YQK A;  1OY5 A;  4YQ7 A;  1Z85 A;  2O3A A;  4YQT A;  4PZK A;  3KTY A;  4YQI A;  4YQD A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...