4YYPA

Crystal structure of human plk4-pb3 in complex with stil-cc
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
87
structure length
87
Chain Sequence
SAQLLKSVFVKNVGWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLSSILLMFSNPTPNFH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title STIL binding to Polo-box 3 of PLK4 regulates centriole duplication.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Serine/threonine-protein kinase PLK4
total genus 19
structure length 87
sequence length 87
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2015-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 4yypA00
4RS6A 3P2ZA 3P37A 4WHKA 4E9DA 3HIKA 4HY2A 4E67A 3C5LA 4O6WA 3FVHA 4WHLA 1UMWA 4X9VA 4HCOA 3Q1IA 4X9RA 4J7BB 4O9WA 3P35A 3RQ7A 4LKMA 5LHZA 1Q4KA 4YYPA 4O56A 4XB0A 5J19A 5DMVC 4WHHA 2OJXA 3P2WA 3BZIA 4HABA 5DMSA 4E9CA 2N19A 3HIHA 3P34A 2OGQA 4H5XA 4LKLA 3P36A 1Q4OA 4H71A 4X9WA 5DNJA 4RCPA 4DFWA
chains in the Genus database with same CATH superfamily
1P49A 3HIKA 3LXQA 4E67A 4N7VA 2I9XA 4N9JA 3FVHA 4O6WA 4HCOA 1E33P 1N2LA 4O9WA 1FSUA 3RQ7A 1Q4KA 2OJXA 3P2WA 4FDJA 4E9CA 3GYWA 1E2SP 4H5XA 4LKLA 3P36A 4CXUA 4X9WA 3GYVA 1E1ZP 2QZUA 4WHLA 1UMWA 2UV8G 3Q1IA 2I9ZA 4X9RA 1F34B 4LKMA 1AUKA 5LHZA 1E3CP 4XB0A 2VKZG 5DMVC 4WHHA 4G7NA 3HIHA 3P34A 4H71A 4DFWA 4YYPA 3KDRA 2E50A 3P2ZA 3P37A 4RS6A 4WHKA 4HY2A 4NKBA 4X9VA 3HMJG 4J7BB 4FDIA 4NK7A 4CYSA 3FS3A 3LM3A 5DMSA 2OGQA 1E2TA 5DNJA 1HDHA 4RCPA 4E9DA 1N2KA 3HFDA 3C5LA 1F32A 4CYRA 3ED4A 4N7ZA 5AJ9A 1A87A 4CXSA 3P35A 5J19A 4O56A 5DAYA 3BZIA 4HABA 2N19A 2IA9A 4CXKA 1Q4OA
chains in the Genus database with same CATH topology
4RS6A 3P2ZA 3P37A 4WHKA 4E9DA 3HIKA 4HY2A 4E67A 3C5LA 4O6WA 3FVHA 4WHLA 1UMWA 4X9VA 4HCOA 3Q1IA 4X9RA 4J7BB 4O9WA 3P35A 3RQ7A 4LKMA 5LHZA 1Q4KA 4YYPA 4O56A 4XB0A 5J19A 5DMVC 4WHHA 2OJXA 3P2WA 3BZIA 4HABA 5DMSA 4E9CA 2N19A 3HIHA 3P34A 2OGQA 4H5XA 4LKLA 3P36A 1Q4OA 4H71A 4X9WA 5DNJA 4RCPA 4DFWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RS6 A;  3P2Z A;  3P37 A;  4WHK A;  4E9D A;  3HIK A;  4HY2 A;  4E67 A;  3C5L A;  4O6W A;  3FVH A;  4WHL A;  1UMW A;  4X9V A;  4HCO A;  3Q1I A;  4X9R A;  4J7B B;  4O9W A;  3P35 A;  3RQ7 A;  4LKM A;  5LHZ A;  1Q4K A;  4YYP A;  4O56 A;  4XB0 A;  5J19 A;  5DMV C;  4WHH A;  2OJX A;  3P2W A;  3BZI A;  4HAB A;  5DMS A;  4E9C A;  2N19 A;  3HIH A;  3P34 A;  2OGQ A;  4H5X A;  4LKL A;  3P36 A;  1Q4O A;  4H71 A;  4X9W A;  5DNJ A;  4RCP A;  4DFW A; 
#chains in the Genus database with same CATH topology
 1P49 A;  3HIK A;  3LXQ A;  4E67 A;  4N7V A;  2I9X A;  4N9J A;  3FVH A;  4O6W A;  4HCO A;  1E33 P;  1N2L A;  4O9W A;  1FSU A;  3RQ7 A;  1Q4K A;  2OJX A;  3P2W A;  4FDJ A;  4E9C A;  3GYW A;  1E2S P;  4H5X A;  4LKL A;  3P36 A;  4CXU A;  4X9W A;  3GYV A;  1E1Z P;  2QZU A;  4WHL A;  1UMW A;  2UV8 G;  3Q1I A;  2I9Z A;  4X9R A;  1F34 B;  4LKM A;  1AUK A;  5LHZ A;  1E3C P;  4XB0 A;  2VKZ G;  5DMV C;  4WHH A;  4G7N A;  3HIH A;  3P34 A;  4H71 A;  4DFW A;  4YYP A;  3KDR A;  2E50 A;  3P2Z A;  3P37 A;  4RS6 A;  4WHK A;  4HY2 A;  4NKB A;  4X9V A;  3HMJ G;  4J7B B;  4FDI A;  4NK7 A;  4CYS A;  3FS3 A;  3LM3 A;  5DMS A;  2OGQ A;  1E2T A;  5DNJ A;  1HDH A;  4RCP A;  4E9D A;  1N2K A;  3HFD A;  3C5L A;  1F32 A;  4CYR A;  3ED4 A;  4N7Z A;  5AJ9 A;  1A87 A;  4CXS A;  3P35 A;  5J19 A;  4O56 A;  5DAY A;  3BZI A;  4HAB A;  2N19 A;  2IA9 A;  4CXK A;  1Q4O A; 
#chains in the Genus database with same CATH homology
 4RS6 A;  3P2Z A;  3P37 A;  4WHK A;  4E9D A;  3HIK A;  4HY2 A;  4E67 A;  3C5L A;  4O6W A;  3FVH A;  4WHL A;  1UMW A;  4X9V A;  4HCO A;  3Q1I A;  4X9R A;  4J7B B;  4O9W A;  3P35 A;  3RQ7 A;  4LKM A;  5LHZ A;  1Q4K A;  4YYP A;  4O56 A;  4XB0 A;  5J19 A;  5DMV C;  4WHH A;  2OJX A;  3P2W A;  3BZI A;  4HAB A;  5DMS A;  4E9C A;  2N19 A;  3HIH A;  3P34 A;  2OGQ A;  4H5X A;  4LKL A;  3P36 A;  1Q4O A;  4H71 A;  4X9W A;  5DNJ A;  4RCP A;  4DFW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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