4Z09A

Crystal structure of fvo strain plasmodium falciparum ama1 in complex with the ron2hp [thr2040ala] peptide
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
331
structure length
270
Chain Sequence
NPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIETTFLKPVKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLCSRHAGNMNPDNDKNSNYKYPAVYDYNDKKCHILYIAAQENNFCFRPAKDKLFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSANDLFECNKLVFELSASDQPKQRYKSHGKGYNWGNYNRETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell invasion
molecule keywords Apical membrane antigen 1
publication title Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
pubmed doi rcsb
source organism Plasmodium falciparum vietnam oak-knoll (fvo)
total genus 78
structure length 270
sequence length 331
ec nomenclature
pdb deposition date 2015-03-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4z09A01
1W8KA 5CS3A 2YILA 4R1AA 2LL3A 2Z8WA 2K13X 1I8NA 3MKPA 5I25A 2J8JA 1GP9A 3ZWZA 2F83A 1GMNA 4Z0DA 4R19A 3HMTA 4UAOA 4A5TS 2YIOA 3SRJA 4IUAA 1HKYA 1NK1A 2X2ZA 4R1BA 2HGFA 3HN4A 5CT2A 2Z8VA 2Y8RA 5CT1A 3SRIA 3ZLEA 5EOKA 1W81A 4APLA 5CS1A 2J8LA 5CS9A 5EODA 5CP9A 4Z0FA 4DURA 1BHTA 4R1CA 4APMA 2Q8BA 5CT3A 2QJ4A 2LL4M 5CS5A 1YXEA 2Q8AA 3HMSA 5CSQA 3SP8A 1GMOA 1Z40A 2QJ2A 2YIPA 4UV6A 3HMRA 4Z0EA 4Z09A 5COEA
chains in the Genus database with same CATH superfamily
4YIVA 1W8KA 5CS3A 2YILA 4R1AA 2LL3A 2Z8WA 2K13X 1I8NA 3MKPA 5I25A 2J8JA 1GP9A 3ZWZA 2F83A 1GMNA 4Z0DA 4R19A 3HMTA 4UAOA 4A5TS 2YIOA 3SRJA 4IUAA 1HKYA 1NK1A 2X2ZA 4R1BA 2HGFA 3HN4A 4YIZA 2Z8VA 5CT2A 2Y8RA 5CT1A 3SRIA 3ZLEA 5EOKA 1W81A 4APLA 5CS1A 2J8LA 5CS9A 5EODA 5CP9A 4Z0FA 4DURA 1BHTA 4R1CA 4APMA 2KL5A 2Q8BA 5CT3A 2QJ4A 2LL4M 5CS5A 1YXEA 2Q8AA 3HMSA 5CSQA 3SP8A 1GMOA 1Z40A 2QJ2A 2YIPA 4UV6A 3HMRA 4Z0EA 4Z09A 5COEA
chains in the Genus database with same CATH topology
4YIVA 1W8KA 5CS3A 2YILA 4R1AA 2LL3A 2Z8WA 2K13X 1I8NA 3MKPA 5I25A 2J8JA 1GP9A 3ZWZA 2F83A 1GMNA 4Z0DA 4R19A 3HMTA 4UAOA 4A5TS 2YIOA 3SRJA 4IUAA 1HKYA 1NK1A 2X2ZA 4R1BA 2HGFA 3HN4A 4YIZA 2Z8VA 5CT2A 2Y8RA 5CT1A 3SRIA 3ZLEA 5EOKA 1W81A 4APLA 5CS1A 2J8LA 5CS9A 5EODA 5CP9A 4Z0FA 4DURA 1BHTA 4R1CA 4APMA 2KL5A 2Q8BA 5CT3A 2QJ4A 2LL4M 5CS5A 1YXEA 2Q8AA 3HMSA 5CSQA 3SP8A 1GMOA 1Z40A 2QJ2A 2YIPA 4UV6A 3HMRA 4Z0EA 4Z09A 5COEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W8K A;  5CS3 A;  2YIL A;  4R1A A;  2LL3 A;  2Z8W A;  2K13 X;  1I8N A;  3MKP A;  5I25 A;  2J8J A;  1GP9 A;  3ZWZ A;  2F83 A;  1GMN A;  4Z0D A;  4R19 A;  3HMT A;  4UAO A;  4A5T S;  2YIO A;  3SRJ A;  4IUA A;  1HKY A;  1NK1 A;  2X2Z A;  4R1B A;  2HGF A;  3HN4 A;  5CT2 A;  2Z8V A;  2Y8R A;  5CT1 A;  3SRI A;  3ZLE A;  5EOK A;  1W81 A;  4APL A;  5CS1 A;  2J8L A;  5CS9 A;  5EOD A;  5CP9 A;  4Z0F A;  4DUR A;  1BHT A;  4R1C A;  4APM A;  2Q8B A;  5CT3 A;  2QJ4 A;  2LL4 M;  5CS5 A;  1YXE A;  2Q8A A;  3HMS A;  5CSQ A;  3SP8 A;  1GMO A;  1Z40 A;  2QJ2 A;  2YIP A;  4UV6 A;  3HMR A;  4Z0E A;  4Z09 A;  5COE A; 
#chains in the Genus database with same CATH topology
 4YIV A;  1W8K A;  5CS3 A;  2YIL A;  4R1A A;  2LL3 A;  2Z8W A;  2K13 X;  1I8N A;  3MKP A;  5I25 A;  2J8J A;  1GP9 A;  3ZWZ A;  2F83 A;  1GMN A;  4Z0D A;  4R19 A;  3HMT A;  4UAO A;  4A5T S;  2YIO A;  3SRJ A;  4IUA A;  1HKY A;  1NK1 A;  2X2Z A;  4R1B A;  2HGF A;  3HN4 A;  4YIZ A;  2Z8V A;  5CT2 A;  2Y8R A;  5CT1 A;  3SRI A;  3ZLE A;  5EOK A;  1W81 A;  4APL A;  5CS1 A;  2J8L A;  5CS9 A;  5EOD A;  5CP9 A;  4Z0F A;  4DUR A;  1BHT A;  4R1C A;  4APM A;  2KL5 A;  2Q8B A;  5CT3 A;  2QJ4 A;  2LL4 M;  5CS5 A;  1YXE A;  2Q8A A;  3HMS A;  5CSQ A;  3SP8 A;  1GMO A;  1Z40 A;  2QJ2 A;  2YIP A;  4UV6 A;  3HMR A;  4Z0E A;  4Z09 A;  5COE A; 
#chains in the Genus database with same CATH homology
 4YIV A;  1W8K A;  5CS3 A;  2YIL A;  4R1A A;  2LL3 A;  2Z8W A;  2K13 X;  1I8N A;  3MKP A;  5I25 A;  2J8J A;  1GP9 A;  3ZWZ A;  2F83 A;  1GMN A;  4Z0D A;  4R19 A;  3HMT A;  4UAO A;  4A5T S;  2YIO A;  3SRJ A;  4IUA A;  1HKY A;  1NK1 A;  2X2Z A;  4R1B A;  2HGF A;  3HN4 A;  4YIZ A;  2Z8V A;  5CT2 A;  2Y8R A;  5CT1 A;  3SRI A;  3ZLE A;  5EOK A;  1W81 A;  4APL A;  5CS1 A;  2J8L A;  5CS9 A;  5EOD A;  5CP9 A;  4Z0F A;  4DUR A;  1BHT A;  4R1C A;  4APM A;  2KL5 A;  2Q8B A;  5CT3 A;  2QJ4 A;  2LL4 M;  5CS5 A;  1YXE A;  2Q8A A;  3HMS A;  5CSQ A;  3SP8 A;  1GMO A;  1Z40 A;  2QJ2 A;  2YIP A;  4UV6 A;  3HMR A;  4Z0E A;  4Z09 A;  5COE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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