4Z09A

Crystal structure of fvo strain plasmodium falciparum ama1 in complex with the ron2hp [thr2040ala] peptide
Total Genus 78
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
331
structure length
270
Chain Sequence
NPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIETTFLKPVKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLCSRHAGNMNPDNDKNSNYKYPAVYDYNDKKCHILYIAAQENNFCFRPAKDKLFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSANDLFECNKLVFELSASDQPKQRYKSHGKGYNWGNYNRETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords Apical membrane antigen 1
publication title Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
pubmed doi rcsb
source organism Plasmodium falciparum vietnam oak-knoll (fvo)
molecule tags Cell invasion
total genus 78
structure length 270
sequence length 331
ec nomenclature
pdb deposition date 2015-03-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4z09A01
1GMOA 2HGFA 3HMRA 2Q8BA 5CSQA 4Z0FA 2Z8VA 4A5TS 2YIOA 2J8JA 4UAOA 4UV6A 1NK1A 3SP8A 4APLA 5CS3A 5EOKA 2QJ2A 4APMA 5CS1A 3HMSA 5CP9A 2Q8AA 5EODA 4R1BA 2Y8RA 1Z40A 1GMNA 3MKPA 1GP9A 3ZLEA 1I8NA 4R19A 3ZWZA 1W8KA 4Z09A 2X2ZA 1W81A 1HKYA 1BHTA 5COEA 5CS9A 2K13X 2Z8WA 5CT2A 2F83A 2YILA 5CS5A 4Z0EA 1YXEA 5CT1A 2J8LA 4R1AA 5CT3A 3SRIA 5I25A 2QJ4A 2LL4M 4DURA 2LL3A 3HN4A 2YIPA 4IUAA 3HMTA 4Z0DA 3SRJA 4R1CA
chains in the Genus database with same CATH superfamily
1GMOA 2HGFA 3HMRA 2Q8BA 5CSQA 4Z0FA 2Z8VA 2KL5A 4A5TS 2YIOA 4YIZA 2J8JA 4UAOA 4UV6A 1NK1A 3SP8A 4APLA 5CS3A 5EOKA 2QJ2A 4APMA 5CS1A 3HMSA 5CP9A 2Q8AA 5EODA 4R1BA 2Y8RA 1Z40A 1GMNA 3MKPA 1GP9A 4Z0DA 1I8NA 3ZLEA 4R19A 3ZWZA 1W8KA 4Z09A 2X2ZA 1W81A 1HKYA 1BHTA 5COEA 5CS9A 2K13X 2Z8WA 5CT2A 2F83A 2YILA 5CS5A 4Z0EA 1YXEA 5CT1A 2J8LA 4R1AA 5CT3A 3SRIA 5I25A 2QJ4A 2LL4M 4DURA 2LL3A 3HN4A 2YIPA 4IUAA 3HMTA 4YIVA 3SRJA 4R1CA
chains in the Genus database with same CATH topology
1GMOA 2HGFA 3HMRA 2Q8BA 5CSQA 4Z0FA 2Z8VA 2KL5A 4A5TS 2YIOA 4YIZA 2J8JA 4UAOA 4UV6A 1NK1A 3SP8A 4APLA 5CS3A 5EOKA 2QJ2A 4APMA 5CS1A 3HMSA 5CP9A 2Q8AA 5EODA 4R1BA 2Y8RA 1Z40A 1GMNA 3MKPA 1GP9A 4Z0DA 1I8NA 3ZLEA 4R19A 3ZWZA 1W8KA 4Z09A 2X2ZA 1W81A 1HKYA 1BHTA 5COEA 5CS9A 2K13X 2Z8WA 5CT2A 2F83A 2YILA 5CS5A 4Z0EA 1YXEA 5CT1A 2J8LA 4R1AA 5CT3A 3SRIA 5I25A 2QJ4A 2LL4M 4DURA 2LL3A 3HN4A 2YIPA 4IUAA 3HMTA 4YIVA 3SRJA 4R1CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GMO A;  2HGF A;  3HMR A;  2Q8B A;  5CSQ A;  4Z0F A;  2Z8V A;  4A5T S;  2YIO A;  2J8J A;  4UAO A;  4UV6 A;  1NK1 A;  3SP8 A;  4APL A;  5CS3 A;  5EOK A;  2QJ2 A;  4APM A;  5CS1 A;  3HMS A;  5CP9 A;  2Q8A A;  5EOD A;  4R1B A;  2Y8R A;  1Z40 A;  1GMN A;  3MKP A;  1GP9 A;  3ZLE A;  1I8N A;  4R19 A;  3ZWZ A;  1W8K A;  4Z09 A;  2X2Z A;  1W81 A;  1HKY A;  1BHT A;  5COE A;  5CS9 A;  2K13 X;  2Z8W A;  5CT2 A;  2F83 A;  2YIL A;  5CS5 A;  4Z0E A;  1YXE A;  5CT1 A;  2J8L A;  4R1A A;  5CT3 A;  3SRI A;  5I25 A;  2QJ4 A;  2LL4 M;  4DUR A;  2LL3 A;  3HN4 A;  2YIP A;  4IUA A;  3HMT A;  4Z0D A;  3SRJ A;  4R1C A; 
#chains in the Genus database with same CATH topology
 1GMO A;  2HGF A;  3HMR A;  2Q8B A;  5CSQ A;  4Z0F A;  2Z8V A;  2KL5 A;  4A5T S;  2YIO A;  4YIZ A;  2J8J A;  4UAO A;  4UV6 A;  1NK1 A;  3SP8 A;  4APL A;  5CS3 A;  5EOK A;  2QJ2 A;  4APM A;  5CS1 A;  3HMS A;  5CP9 A;  2Q8A A;  5EOD A;  4R1B A;  2Y8R A;  1Z40 A;  1GMN A;  3MKP A;  1GP9 A;  4Z0D A;  1I8N A;  3ZLE A;  4R19 A;  3ZWZ A;  1W8K A;  4Z09 A;  2X2Z A;  1W81 A;  1HKY A;  1BHT A;  5COE A;  5CS9 A;  2K13 X;  2Z8W A;  5CT2 A;  2F83 A;  2YIL A;  5CS5 A;  4Z0E A;  1YXE A;  5CT1 A;  2J8L A;  4R1A A;  5CT3 A;  3SRI A;  5I25 A;  2QJ4 A;  2LL4 M;  4DUR A;  2LL3 A;  3HN4 A;  2YIP A;  4IUA A;  3HMT A;  4YIV A;  3SRJ A;  4R1C A; 
#chains in the Genus database with same CATH homology
 1GMO A;  2HGF A;  3HMR A;  2Q8B A;  5CSQ A;  4Z0F A;  2Z8V A;  2KL5 A;  4A5T S;  2YIO A;  4YIZ A;  2J8J A;  4UAO A;  4UV6 A;  1NK1 A;  3SP8 A;  4APL A;  5CS3 A;  5EOK A;  2QJ2 A;  4APM A;  5CS1 A;  3HMS A;  5CP9 A;  2Q8A A;  5EOD A;  4R1B A;  2Y8R A;  1Z40 A;  1GMN A;  3MKP A;  1GP9 A;  4Z0D A;  1I8N A;  3ZLE A;  4R19 A;  3ZWZ A;  1W8K A;  4Z09 A;  2X2Z A;  1W81 A;  1HKY A;  1BHT A;  5COE A;  5CS9 A;  2K13 X;  2Z8W A;  5CT2 A;  2F83 A;  2YIL A;  5CS5 A;  4Z0E A;  1YXE A;  5CT1 A;  2J8L A;  4R1A A;  5CT3 A;  3SRI A;  5I25 A;  2QJ4 A;  2LL4 M;  4DUR A;  2LL3 A;  3HN4 A;  2YIP A;  4IUA A;  3HMT A;  4YIV A;  3SRJ A;  4R1C A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...