4Z0DA

Crystal structure of fvo strain plasmodium falciparum ama1 in complex with the ron2hp [phe2038trp] peptide
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
331
structure length
273
Chain Sequence
NPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIETTFLKPVATLKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLCSRHAGNMNPDNDKNSNYKYPAVYDYNDKKCHILYIAAQENNFCFRPAKDKLFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSANDLFECNKLVFELSASDQPKDRYKSHGKGYNWGNYNRETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell invasion
molecule keywords Apical membrane antigen 1
publication title Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
pubmed doi rcsb
source organism Plasmodium falciparum vietnam oak-knoll (fvo)
total genus 74
structure length 273
sequence length 331
ec nomenclature
pdb deposition date 2015-03-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4z0dA01
3HMRA 3ZLEA 1NK1A 2Z8WA 4R19A 4R1BA 5CS1A 5CT1A 4UV6A 5EODA 2LL3A 5CT3A 4APLA 5I25A 4IUAA 4Z09A 3HMTA 2Q8BA 2QJ4A 4R1CA 2Y8RA 4Z0EA 2YILA 2J8JA 1W81A 2LL4M 4R1AA 2HGFA 4Z0DA 3SP8A 2F83A 1GP9A 1BHTA 2K13X 3MKPA 2Z8VA 5CS3A 2Q8AA 2QJ2A 1GMOA 1I8NA 2J8LA 3HMSA 1HKYA 1Z40A 5CT2A 5CSQA 5CS5A 1YXEA 5CP9A 4DURA 4Z0FA 5EOKA 4UAOA 5COEA 5CS9A 3SRJA 4APMA 3ZWZA 3HN4A 2X2ZA 2YIPA 3SRIA 4A5TS 1W8KA 2YIOA 1GMNA
chains in the Genus database with same CATH superfamily
3HMRA 3ZLEA 1NK1A 2Z8WA 4R19A 4R1BA 5CS1A 5CT1A 2KL5A 4UV6A 5EODA 2LL3A 5CT3A 4APLA 5I25A 4YIVA 4IUAA 4Z09A 3HMTA 2Q8BA 2QJ4A 4R1CA 2Y8RA 4Z0EA 2YILA 2J8JA 1W81A 2LL4M 4R1AA 2HGFA 4Z0DA 3SP8A 2F83A 1GP9A 1BHTA 2K13X 3MKPA 2Z8VA 4YIZA 5CS3A 2Q8AA 2QJ2A 1GMOA 1I8NA 2J8LA 3HMSA 1HKYA 1Z40A 5CT2A 5CSQA 5CS5A 1YXEA 5CP9A 4DURA 4Z0FA 5EOKA 4UAOA 5COEA 5CS9A 3SRJA 4APMA 3ZWZA 3HN4A 2X2ZA 2YIPA 3SRIA 4A5TS 1W8KA 2YIOA 1GMNA
chains in the Genus database with same CATH topology
3HMRA 3ZLEA 1NK1A 2Z8WA 4R19A 4R1BA 5CS1A 5CT1A 2KL5A 4UV6A 5EODA 2LL3A 5CT3A 4APLA 5I25A 4YIVA 4IUAA 4Z09A 3HMTA 2Q8BA 2QJ4A 4R1CA 2Y8RA 4Z0EA 2YILA 2J8JA 1W81A 2LL4M 4R1AA 2HGFA 4Z0DA 3SP8A 2F83A 1GP9A 1BHTA 2K13X 3MKPA 2Z8VA 4YIZA 5CS3A 2Q8AA 2QJ2A 1GMOA 1I8NA 2J8LA 3HMSA 1HKYA 1Z40A 5CT2A 5CSQA 5CS5A 1YXEA 5CP9A 4DURA 4Z0FA 5EOKA 4UAOA 5COEA 5CS9A 3SRJA 4APMA 3ZWZA 3HN4A 2X2ZA 2YIPA 3SRIA 4A5TS 1W8KA 2YIOA 1GMNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HMR A;  3ZLE A;  1NK1 A;  2Z8W A;  4R19 A;  4R1B A;  5CS1 A;  5CT1 A;  4UV6 A;  5EOD A;  2LL3 A;  5CT3 A;  4APL A;  5I25 A;  4IUA A;  4Z09 A;  3HMT A;  2Q8B A;  2QJ4 A;  4R1C A;  2Y8R A;  4Z0E A;  2YIL A;  2J8J A;  1W81 A;  2LL4 M;  4R1A A;  2HGF A;  4Z0D A;  3SP8 A;  2F83 A;  1GP9 A;  1BHT A;  2K13 X;  3MKP A;  2Z8V A;  5CS3 A;  2Q8A A;  2QJ2 A;  1GMO A;  1I8N A;  2J8L A;  3HMS A;  1HKY A;  1Z40 A;  5CT2 A;  5CSQ A;  5CS5 A;  1YXE A;  5CP9 A;  4DUR A;  4Z0F A;  5EOK A;  4UAO A;  5COE A;  5CS9 A;  3SRJ A;  4APM A;  3ZWZ A;  3HN4 A;  2X2Z A;  2YIP A;  3SRI A;  4A5T S;  1W8K A;  2YIO A;  1GMN A; 
#chains in the Genus database with same CATH topology
 3HMR A;  3ZLE A;  1NK1 A;  2Z8W A;  4R19 A;  4R1B A;  5CS1 A;  5CT1 A;  2KL5 A;  4UV6 A;  5EOD A;  2LL3 A;  5CT3 A;  4APL A;  5I25 A;  4YIV A;  4IUA A;  4Z09 A;  3HMT A;  2Q8B A;  2QJ4 A;  4R1C A;  2Y8R A;  4Z0E A;  2YIL A;  2J8J A;  1W81 A;  2LL4 M;  4R1A A;  2HGF A;  4Z0D A;  3SP8 A;  2F83 A;  1GP9 A;  1BHT A;  2K13 X;  3MKP A;  2Z8V A;  4YIZ A;  5CS3 A;  2Q8A A;  2QJ2 A;  1GMO A;  1I8N A;  2J8L A;  3HMS A;  1HKY A;  1Z40 A;  5CT2 A;  5CSQ A;  5CS5 A;  1YXE A;  5CP9 A;  4DUR A;  4Z0F A;  5EOK A;  4UAO A;  5COE A;  5CS9 A;  3SRJ A;  4APM A;  3ZWZ A;  3HN4 A;  2X2Z A;  2YIP A;  3SRI A;  4A5T S;  1W8K A;  2YIO A;  1GMN A; 
#chains in the Genus database with same CATH homology
 3HMR A;  3ZLE A;  1NK1 A;  2Z8W A;  4R19 A;  4R1B A;  5CS1 A;  5CT1 A;  2KL5 A;  4UV6 A;  5EOD A;  2LL3 A;  5CT3 A;  4APL A;  5I25 A;  4YIV A;  4IUA A;  4Z09 A;  3HMT A;  2Q8B A;  2QJ4 A;  4R1C A;  2Y8R A;  4Z0E A;  2YIL A;  2J8J A;  1W81 A;  2LL4 M;  4R1A A;  2HGF A;  4Z0D A;  3SP8 A;  2F83 A;  1GP9 A;  1BHT A;  2K13 X;  3MKP A;  2Z8V A;  4YIZ A;  5CS3 A;  2Q8A A;  2QJ2 A;  1GMO A;  1I8N A;  2J8L A;  3HMS A;  1HKY A;  1Z40 A;  5CT2 A;  5CSQ A;  5CS5 A;  1YXE A;  5CP9 A;  4DUR A;  4Z0F A;  5EOK A;  4UAO A;  5COE A;  5CS9 A;  3SRJ A;  4APM A;  3ZWZ A;  3HN4 A;  2X2Z A;  2YIP A;  3SRI A;  4A5T S;  1W8K A;  2YIO A;  1GMN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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