4Z0DA

Crystal structure of fvo strain plasmodium falciparum ama1 in complex with the ron2hp [phe2038trp] peptide
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
331
structure length
273
Chain Sequence
NPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIETTFLKPVATLKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLCSRHAGNMNPDNDKNSNYKYPAVYDYNDKKCHILYIAAQENNFCFRPAKDKLFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSANDLFECNKLVFELSASDQPKDRYKSHGKGYNWGNYNRETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
pubmed doi rcsb
molecule tags Cell invasion
source organism Plasmodium falciparum vietnam oak-knoll (fvo)
molecule keywords Apical membrane antigen 1
total genus 74
structure length 273
sequence length 331
ec nomenclature
pdb deposition date 2015-03-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4z0dA01
2YIOA 5CSQA 5CT2A 3ZLEA 1GMOA 1W8KA 3MKPA 5CS9A 2K13X 1YXEA 2LL3A 5EODA 2YIPA 2Q8BA 4Z0FA 4Z0EA 2Z8VA 1GMNA 5CS3A 5CP9A 5CS1A 5CS5A 2Y8RA 3HN4A 1Z40A 3ZWZA 1GP9A 4R19A 3SP8A 3HMSA 2LL4M 4R1AA 5CT1A 5I25A 5COEA 5EOKA 4APLA 2QJ2A 2J8JA 3HMRA 4A5TS 4APMA 2Q8AA 4R1CA 2J8LA 1I8NA 4UV6A 4Z0DA 2YILA 2HGFA 2F83A 3HMTA 2Z8WA 3SRIA 1W81A 2QJ4A 4IUAA 4R1BA 4UAOA 5CT3A 2X2ZA 1BHTA 4Z09A 3SRJA 4DURA 1HKYA 1NK1A
chains in the Genus database with same CATH superfamily
2YIOA 5CSQA 5CT2A 3ZLEA 1GMOA 1W8KA 3MKPA 5CS9A 2K13X 1YXEA 2LL3A 5EODA 2YIPA 2Q8BA 4Z0FA 2KL5A 4Z0EA 2Z8VA 1GMNA 5CS3A 5CP9A 5CS1A 5CS5A 2Y8RA 3HN4A 1Z40A 3ZWZA 1GP9A 4R19A 3SP8A 3HMSA 2LL4M 4R1AA 5CT1A 5I25A 5COEA 5EOKA 4YIVA 4APLA 2QJ2A 2J8JA 3HMRA 4A5TS 4APMA 2Q8AA 4R1CA 2J8LA 1I8NA 4UV6A 4Z0DA 2YILA 2HGFA 2F83A 3HMTA 2Z8WA 3SRIA 1W81A 2QJ4A 4IUAA 4R1BA 4UAOA 5CT3A 2X2ZA 1BHTA 4Z09A 3SRJA 4DURA 1HKYA 4YIZA 1NK1A
chains in the Genus database with same CATH topology
2YIOA 5CSQA 5CT2A 3ZLEA 1GMOA 1W8KA 3MKPA 5CS9A 2K13X 1YXEA 2LL3A 5EODA 2YIPA 2Q8BA 4Z0FA 2KL5A 4Z0EA 2Z8VA 1GMNA 5CS3A 5CP9A 5CS1A 5CS5A 2Y8RA 3HN4A 1Z40A 3ZWZA 1GP9A 4R19A 3SP8A 3HMSA 2LL4M 4R1AA 5CT1A 5I25A 5COEA 5EOKA 4YIVA 4APLA 2QJ2A 2J8JA 3HMRA 4A5TS 4APMA 2Q8AA 4R1CA 2J8LA 1I8NA 4UV6A 4Z0DA 2YILA 2HGFA 2F83A 3HMTA 2Z8WA 3SRIA 1W81A 2QJ4A 4IUAA 4R1BA 4UAOA 5CT3A 2X2ZA 1BHTA 4Z09A 3SRJA 4DURA 1HKYA 4YIZA 1NK1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YIO A;  5CSQ A;  5CT2 A;  3ZLE A;  1GMO A;  1W8K A;  3MKP A;  5CS9 A;  2K13 X;  1YXE A;  2LL3 A;  5EOD A;  2YIP A;  2Q8B A;  4Z0F A;  4Z0E A;  2Z8V A;  1GMN A;  5CS3 A;  5CP9 A;  5CS1 A;  5CS5 A;  2Y8R A;  3HN4 A;  1Z40 A;  3ZWZ A;  1GP9 A;  4R19 A;  3SP8 A;  3HMS A;  2LL4 M;  4R1A A;  5CT1 A;  5I25 A;  5COE A;  5EOK A;  4APL A;  2QJ2 A;  2J8J A;  3HMR A;  4A5T S;  4APM A;  2Q8A A;  4R1C A;  2J8L A;  1I8N A;  4UV6 A;  4Z0D A;  2YIL A;  2HGF A;  2F83 A;  3HMT A;  2Z8W A;  3SRI A;  1W81 A;  2QJ4 A;  4IUA A;  4R1B A;  4UAO A;  5CT3 A;  2X2Z A;  1BHT A;  4Z09 A;  3SRJ A;  4DUR A;  1HKY A;  1NK1 A; 
#chains in the Genus database with same CATH topology
 2YIO A;  5CSQ A;  5CT2 A;  3ZLE A;  1GMO A;  1W8K A;  3MKP A;  5CS9 A;  2K13 X;  1YXE A;  2LL3 A;  5EOD A;  2YIP A;  2Q8B A;  4Z0F A;  2KL5 A;  4Z0E A;  2Z8V A;  1GMN A;  5CS3 A;  5CP9 A;  5CS1 A;  5CS5 A;  2Y8R A;  3HN4 A;  1Z40 A;  3ZWZ A;  1GP9 A;  4R19 A;  3SP8 A;  3HMS A;  2LL4 M;  4R1A A;  5CT1 A;  5I25 A;  5COE A;  5EOK A;  4YIV A;  4APL A;  2QJ2 A;  2J8J A;  3HMR A;  4A5T S;  4APM A;  2Q8A A;  4R1C A;  2J8L A;  1I8N A;  4UV6 A;  4Z0D A;  2YIL A;  2HGF A;  2F83 A;  3HMT A;  2Z8W A;  3SRI A;  1W81 A;  2QJ4 A;  4IUA A;  4R1B A;  4UAO A;  5CT3 A;  2X2Z A;  1BHT A;  4Z09 A;  3SRJ A;  4DUR A;  1HKY A;  4YIZ A;  1NK1 A; 
#chains in the Genus database with same CATH homology
 2YIO A;  5CSQ A;  5CT2 A;  3ZLE A;  1GMO A;  1W8K A;  3MKP A;  5CS9 A;  2K13 X;  1YXE A;  2LL3 A;  5EOD A;  2YIP A;  2Q8B A;  4Z0F A;  2KL5 A;  4Z0E A;  2Z8V A;  1GMN A;  5CS3 A;  5CP9 A;  5CS1 A;  5CS5 A;  2Y8R A;  3HN4 A;  1Z40 A;  3ZWZ A;  1GP9 A;  4R19 A;  3SP8 A;  3HMS A;  2LL4 M;  4R1A A;  5CT1 A;  5I25 A;  5COE A;  5EOK A;  4YIV A;  4APL A;  2QJ2 A;  2J8J A;  3HMR A;  4A5T S;  4APM A;  2Q8A A;  4R1C A;  2J8L A;  1I8N A;  4UV6 A;  4Z0D A;  2YIL A;  2HGF A;  2F83 A;  3HMT A;  2Z8W A;  3SRI A;  1W81 A;  2QJ4 A;  4IUA A;  4R1B A;  4UAO A;  5CT3 A;  2X2Z A;  1BHT A;  4Z09 A;  3SRJ A;  4DUR A;  1HKY A;  4YIZ A;  1NK1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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