4Z69A

Human serum albumin complexed with palmitic acid and diclofenac
Total Genus 227
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
227
sequence length
581
structure length
581
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural basis of non-steroidal anti-inflammatory drug diclofenac binding to human serum albumin.
pubmed doi rcsb
molecule keywords Serum albumin
molecule tags Transport protein
source organism Homo sapiens
total genus 227
structure length 581
sequence length 581
chains with identical sequence I
ec nomenclature
pdb deposition date 2015-04-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z69A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z69A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z69A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z69A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z69A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z69A05
1E78A 4G04A 2XVUA 3B9MA 3CX9A 2BXDA 1E7CA 1BM0A 3LU7A 3UIVA 1HA2A 2I30A 2BXNA 2XSIA 1HK5A 1J7EA 4N0FD 3TDLA 4K2CA 4LUHA 4BKEA 2BXLA 1N5UA 4HGKA 5HOZA 1KXPD 1MA9A 3LU8A 2VUEA 2BXBA 5GHKA 1GNJA 4LB2A 4ZBQA 4N0UD 3LU6A 1HK2A 1UORA 4LB9A 1E7FA 2I2ZA 4OT2A 1AO6A 1KW2A 4L9QA 2BX8A 2XVQA 2XVWA 5ID9A 1H9ZA 2XW1A 1E7BA 2VDBA 2XVVA 5IFOA 2BXAA 5IJFA 5IIXA 1E7GA 1LOTA 4IW2A 3JQZA 5FUOA 4F5UA 4E99A 4PO0A 3JRYA 2BXMA 1O9XA 1E7EA 2BXHA 4JK4A 1TF0A 4IW1A 4OR0A 2BXOA 5DQFA 4G03A 1E7AA 5DBYA 4L9KA 4J2VA 4K71A 4LUFA 4S1YA 2BXKA 5IJ5A 2VUFA 1E7HA 4F5VA 5IIHA 4F5TA 1HK3A 1BKEA 2YDFA 2BXQA 2BXIA 4L8UA 2BXFA 3V08A 4HGMB 4F5SA 5IIUA 1J78A 1BJ5A 1HK1A 2BXPA 3B9LA 3A73A 1E7IA 1GNIA 5ID7A 4ZBRA 3SQJA 3V09A 2BXCA 2XW0A 4LA0A 2BXGA 4Z69A 2BXEA 4EMXA 1HK4A 3V03A 5IJEA
chains in the Genus database with same CATH superfamily
1E78A 5D7GA 1SB0A 4TQ0A 4D7XA 4G04A 3BPJA 1MIYA 2XVUA 2DBXA 4ZC6A 1MIWA 2EFHA 2EFDA 3B9MA 3CX9A 2BXDA 1E7CA 1MUSA 3NMUA 1BM0A 3LU7A 3UIVA 1HA2A 2JUHA 3NVKA 1TXUA 2I30A 4G01A 2BXNA 2XSIA 1HK5A 4GDKB 1J7EA 4N0FD 3TDLA 3A75A 4K2CA 4LUHA 4Z9OA 4BKEA 5IJEA 2BXLA 3GQXA 2NQOA 3H3AA 3FNMA 1N5UA 2DYMA 1JNBA 4HGKA 5HOZA 4WA6B 1KXPD 1MA9A 3LU8A 2VUEA 2BXBA 5GHKA 1GNJA 4LB2A 4ZBQA 2LQIA 4N0UD 3LU6A 1MUHA 1HK2A 4M70B 1LNSA 1UORA 4C31B 5GINA 1VZSA 1IJGA 4LB9A 1E7FA 3G9KD 2I2ZA 2GUTA 4OT2A 1AO6A 2OZBB 1KW2A 2QM6A 4L9QA 3ECPA 2BX8A 2XVQA 2XVWA 1KDXA 3VQIA 2K0NA 5ID9A 2XMOA 1H9ZA 2OT3A 3KIKA 1FOUA 2XW1A 1E7BA 2VDBA 2XVVA 5IFOA 2DBUA 2BXAA 1MIVA 5IIXA 5IJFA 2LXTA 1E7GA 1LOTA 4IW2A 3JQZA 4FIPB 2AJEA 5FUOA 2AGHB 2Z8KA 3H37A 4F5UA 3NVMA 1VFIA 4E99A 2LOQA 4PO0A 4BY9C 2QHBA 1MM8A 3JRYA 4ZBKA 3WHRA 2BXMA 2Z8IA 4DM0A 2EFCA 3SIVB 1O9XA 1E7EA 3GQUA 4FK5B 3PLAA 3KJLA 2BXHA 4JK4A 5GIOA 1TF0A 4IW1A 2DYOA 2KBZA 2EFEA 4OR0A 4TQ1A 2BXOA 3MHSB 5DQFA 4G03A 4FJCB 3GA9L 1E7AA 5BPKA 4ZUXV 5DBYA 2V36A 1NT2B 4J2VA 4L9KA 4OTUA 2KWFA 4K71A 4LUFA 4S1YA 1H5WA 3WHQA 2BXKA 5IJ5A 2VUFA 1E7HA 2ROHA 4F5VA 3ICXA 4OTTA 4W4UB 4F5TA 1HK3A 5IIHA 2LXSA 1BKEA 2YDFA 2Z8JA 2BXQA 2DG5A 3FWBC 3NVIA 2BXIA 4L8UA 2BXFA 2E0YA 3V08A 5GIPA 2DBWA 4HGMB 4NAWB 4F5SA 3MHHB 5IIUA 4MBEC 5B5TA 4ZCGA 1J78A 1BJ5A 3FWCC 3WHSA 1HK1A 3W1SA 4GG2A 2CKXA 2BXPA 3B9LA 3A73A 1E7IA 1GNIA 4I9OA 4ZBRA 3SQJA 5ID7A 3V09A 2BXCA 2QMCA 2XW0A 4GDXA 4LA0A 2BXGA 4N3ZA 4Z69A 2BXEA 4GDLB 2LQHA 4EMXA 4DHXB 3SIUB 2NNWA 1HK4A 3V03A 3M99C 2E0XA
chains in the Genus database with same CATH topology
1E78A 5D7GA 4TQ0A 4G04A 1MIYA 2XVUA 2DBXA 4ZC6A 1MIWA 2EFHA 2EFDA 3B9MA 3CX9A 2BXDA 1E7CA 3NMUA 1BM0A 3LU7A 3UIVA 1HA2A 2JUHA 3NVKA 1TXUA 2I30A 4G01A 2BXNA 2XSIA 1HK5A 4GDKB 1J7EA 4N0FD 3TDLA 3A75A 4K2CA 4LUHA 4Z9OA 4BKEA 5IJEA 2BXLA 3GQXA 2NQOA 3H3AA 3FNMA 1N5UA 2DYMA 1JNBA 4HGKA 5HOZA 4WA6B 1KXPD 1MA9A 3LU8A 2VUEA 2BXBA 5GHKA 1GNJA 4LB2A 4ZBQA 4N0UD 3LU6A 1HK2A 4M70B 1LNSA 1UORA 4C31B 5GINA 1VZSA 1IJGA 4LB9A 1E7FA 3G9KD 2I2ZA 4OT2A 1AO6A 2OZBB 1KW2A 2QM6A 4L9QA 2BX8A 2XVQA 2XVWA 3VQIA 5ID9A 2XMOA 1H9ZA 2OT3A 3KIKA 1FOUA 2XW1A 1E7BA 2VDBA 2XVVA 5IFOA 2DBUA 2BXAA 1MIVA 5IIXA 5IJFA 1E7GA 1LOTA 4IW2A 3JQZA 4FIPB 2AJEA 5FUOA 2Z8KA 3H37A 4F5UA 3NVMA 1VFIA 4E99A 2LOQA 4PO0A 4BY9C 2QHBA 3JRYA 4ZBKA 3WHRA 2BXMA 2Z8IA 2EFCA 3SIVB 1O9XA 1E7EA 3GQUA 4FK5B 3PLAA 3KJLA 2BXHA 4JK4A 5GIOA 1TF0A 4IW1A 2DYOA 2KBZA 2EFEA 4OR0A 4TQ1A 2BXOA 3MHSB 5DQFA 4G03A 4FJCB 3GA9L 1E7AA 5BPKA 4ZUXV 5DBYA 2V36A 1NT2B 4J2VA 4L9KA 4OTUA 4K71A 4LUFA 4S1YA 1H5WA 3WHQA 2BXKA 5IJ5A 2VUFA 1E7HA 2ROHA 4F5VA 3ICXA 4OTTA 4W4UB 4F5TA 1HK3A 5IIHA 1BKEA 2YDFA 2Z8JA 2BXQA 2DG5A 3FWBC 3NVIA 2BXIA 4L8UA 2BXFA 2E0YA 3V08A 5GIPA 2DBWA 4HGMB 4NAWB 4F5SA 3MHHB 5IIUA 4MBEC 5B5TA 4ZCGA 1J78A 1BJ5A 3FWCC 3WHSA 1HK1A 3W1SA 4GG2A 2CKXA 2BXPA 3B9LA 3A73A 1E7IA 1GNIA 5ID7A 4ZBRA 3SQJA 3V09A 2BXCA 2QMCA 2XW0A 4GDXA 4LA0A 2BXGA 4N3ZA 4Z69A 2BXEA 4GDLB 4EMXA 4DHXB 3SIUB 2NNWA 1HK4A 3V03A 3M99C 2E0XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E78 A;  4G04 A;  2XVU A;  3B9M A;  3CX9 A;  2BXD A;  1E7C A;  1BM0 A;  3LU7 A;  3UIV A;  1HA2 A;  2I30 A;  2BXN A;  2XSI A;  1HK5 A;  1J7E A;  4N0F D;  3TDL A;  4K2C A;  4LUH A;  4BKE A;  2BXL A;  1N5U A;  4HGK A;  5HOZ A;  1KXP D;  1MA9 A;  3LU8 A;  2VUE A;  2BXB A;  5GHK A;  1GNJ A;  4LB2 A;  4ZBQ A;  4N0U D;  3LU6 A;  1HK2 A;  1UOR A;  4LB9 A;  1E7F A;  2I2Z A;  4OT2 A;  1AO6 A;  1KW2 A;  4L9Q A;  2BX8 A;  2XVQ A;  2XVW A;  5ID9 A;  1H9Z A;  2XW1 A;  1E7B A;  2VDB A;  2XVV A;  5IFO A;  2BXA A;  5IJF A;  5IIX A;  1E7G A;  1LOT A;  4IW2 A;  3JQZ A;  5FUO A;  4F5U A;  4E99 A;  4PO0 A;  3JRY A;  2BXM A;  1O9X A;  1E7E A;  2BXH A;  4JK4 A;  1TF0 A;  4IW1 A;  4OR0 A;  2BXO A;  5DQF A;  4G03 A;  1E7A A;  5DBY A;  4L9K A;  4J2V A;  4K71 A;  4LUF A;  4S1Y A;  2BXK A;  5IJ5 A;  2VUF A;  1E7H A;  4F5V A;  5IIH A;  4F5T A;  1HK3 A;  1BKE A;  2YDF A;  2BXQ A;  2BXI A;  4L8U A;  2BXF A;  3V08 A;  4HGM B;  4F5S A;  5IIU A;  1J78 A;  1BJ5 A;  1HK1 A;  2BXP A;  3B9L A;  3A73 A;  1E7I A;  1GNI A;  5ID7 A;  4ZBR A;  3SQJ A;  3V09 A;  2BXC A;  2XW0 A;  4LA0 A;  2BXG A;  4Z69 A;  2BXE A;  4EMX A;  1HK4 A;  3V03 A;  5IJE A; 
#chains in the Genus database with same CATH topology
 1E78 A;  5D7G A;  1SB0 A;  4TQ0 A;  4D7X A;  4G04 A;  3BPJ A;  1MIY A;  2XVU A;  2DBX A;  4ZC6 A;  1MIW A;  2EFH A;  2EFD A;  3B9M A;  3CX9 A;  2BXD A;  1E7C A;  1MUS A;  3NMU A;  1BM0 A;  3LU7 A;  3UIV A;  1HA2 A;  2JUH A;  3NVK A;  1TXU A;  2I30 A;  4G01 A;  2BXN A;  2XSI A;  1HK5 A;  4GDK B;  1J7E A;  4N0F D;  3TDL A;  3A75 A;  4K2C A;  4LUH A;  4Z9O A;  4BKE A;  5IJE A;  2BXL A;  3GQX A;  2NQO A;  3H3A A;  3FNM A;  1N5U A;  2DYM A;  1JNB A;  4HGK A;  5HOZ A;  4WA6 B;  1KXP D;  1MA9 A;  3LU8 A;  2VUE A;  2BXB A;  5GHK A;  1GNJ A;  4LB2 A;  4ZBQ A;  2LQI A;  4N0U D;  3LU6 A;  1MUH A;  1HK2 A;  4M70 B;  1LNS A;  1UOR A;  4C31 B;  5GIN A;  1VZS A;  1IJG A;  4LB9 A;  1E7F A;  3G9K D;  2I2Z A;  2GUT A;  4OT2 A;  1AO6 A;  2OZB B;  1KW2 A;  2QM6 A;  4L9Q A;  3ECP A;  2BX8 A;  2XVQ A;  2XVW A;  1KDX A;  3VQI A;  2K0N A;  5ID9 A;  2XMO A;  1H9Z A;  2OT3 A;  3KIK A;  1FOU A;  2XW1 A;  1E7B A;  2VDB A;  2XVV A;  5IFO A;  2DBU A;  2BXA A;  1MIV A;  5IIX A;  5IJF A;  2LXT A;  1E7G A;  1LOT A;  4IW2 A;  3JQZ A;  4FIP B;  2AJE A;  5FUO A;  2AGH B;  2Z8K A;  3H37 A;  4F5U A;  3NVM A;  1VFI A;  4E99 A;  2LOQ A;  4PO0 A;  4BY9 C;  2QHB A;  1MM8 A;  3JRY A;  4ZBK A;  3WHR A;  2BXM A;  2Z8I A;  4DM0 A;  2EFC A;  3SIV B;  1O9X A;  1E7E A;  3GQU A;  4FK5 B;  3PLA A;  3KJL A;  2BXH A;  4JK4 A;  5GIO A;  1TF0 A;  4IW1 A;  2DYO A;  2KBZ A;  2EFE A;  4OR0 A;  4TQ1 A;  2BXO A;  3MHS B;  5DQF A;  4G03 A;  4FJC B;  3GA9 L;  1E7A A;  5BPK A;  4ZUX V;  5DBY A;  2V36 A;  1NT2 B;  4J2V A;  4L9K A;  4OTU A;  2KWF A;  4K71 A;  4LUF A;  4S1Y A;  1H5W A;  3WHQ A;  2BXK A;  5IJ5 A;  2VUF A;  1E7H A;  2ROH A;  4F5V A;  3ICX A;  4OTT A;  4W4U B;  4F5T A;  1HK3 A;  5IIH A;  2LXS A;  1BKE A;  2YDF A;  2Z8J A;  2BXQ A;  2DG5 A;  3FWB C;  3NVI A;  2BXI A;  4L8U A;  2BXF A;  2E0Y A;  3V08 A;  5GIP A;  2DBW A;  4HGM B;  4NAW B;  4F5S A;  3MHH B;  5IIU A;  4MBE C;  5B5T A;  4ZCG A;  1J78 A;  1BJ5 A;  3FWC C;  3WHS A;  1HK1 A;  3W1S A;  4GG2 A;  2CKX A;  2BXP A;  3B9L A;  3A73 A;  1E7I A;  1GNI A;  4I9O A;  4ZBR A;  3SQJ A;  5ID7 A;  3V09 A;  2BXC A;  2QMC A;  2XW0 A;  4GDX A;  4LA0 A;  2BXG A;  4N3Z A;  4Z69 A;  2BXE A;  4GDL B;  2LQH A;  4EMX A;  4DHX B;  3SIU B;  2NNW A;  1HK4 A;  3V03 A;  3M99 C;  2E0X A; 
#chains in the Genus database with same CATH homology
 1E78 A;  5D7G A;  4TQ0 A;  4G04 A;  1MIY A;  2XVU A;  2DBX A;  4ZC6 A;  1MIW A;  2EFH A;  2EFD A;  3B9M A;  3CX9 A;  2BXD A;  1E7C A;  3NMU A;  1BM0 A;  3LU7 A;  3UIV A;  1HA2 A;  2JUH A;  3NVK A;  1TXU A;  2I30 A;  4G01 A;  2BXN A;  2XSI A;  1HK5 A;  4GDK B;  1J7E A;  4N0F D;  3TDL A;  3A75 A;  4K2C A;  4LUH A;  4Z9O A;  4BKE A;  5IJE A;  2BXL A;  3GQX A;  2NQO A;  3H3A A;  3FNM A;  1N5U A;  2DYM A;  1JNB A;  4HGK A;  5HOZ A;  4WA6 B;  1KXP D;  1MA9 A;  3LU8 A;  2VUE A;  2BXB A;  5GHK A;  1GNJ A;  4LB2 A;  4ZBQ A;  4N0U D;  3LU6 A;  1HK2 A;  4M70 B;  1LNS A;  1UOR A;  4C31 B;  5GIN A;  1VZS A;  1IJG A;  4LB9 A;  1E7F A;  3G9K D;  2I2Z A;  4OT2 A;  1AO6 A;  2OZB B;  1KW2 A;  2QM6 A;  4L9Q A;  2BX8 A;  2XVQ A;  2XVW A;  3VQI A;  5ID9 A;  2XMO A;  1H9Z A;  2OT3 A;  3KIK A;  1FOU A;  2XW1 A;  1E7B A;  2VDB A;  2XVV A;  5IFO A;  2DBU A;  2BXA A;  1MIV A;  5IIX A;  5IJF A;  1E7G A;  1LOT A;  4IW2 A;  3JQZ A;  4FIP B;  2AJE A;  5FUO A;  2Z8K A;  3H37 A;  4F5U A;  3NVM A;  1VFI A;  4E99 A;  2LOQ A;  4PO0 A;  4BY9 C;  2QHB A;  3JRY A;  4ZBK A;  3WHR A;  2BXM A;  2Z8I A;  2EFC A;  3SIV B;  1O9X A;  1E7E A;  3GQU A;  4FK5 B;  3PLA A;  3KJL A;  2BXH A;  4JK4 A;  5GIO A;  1TF0 A;  4IW1 A;  2DYO A;  2KBZ A;  2EFE A;  4OR0 A;  4TQ1 A;  2BXO A;  3MHS B;  5DQF A;  4G03 A;  4FJC B;  3GA9 L;  1E7A A;  5BPK A;  4ZUX V;  5DBY A;  2V36 A;  1NT2 B;  4J2V A;  4L9K A;  4OTU A;  4K71 A;  4LUF A;  4S1Y A;  1H5W A;  3WHQ A;  2BXK A;  5IJ5 A;  2VUF A;  1E7H A;  2ROH A;  4F5V A;  3ICX A;  4OTT A;  4W4U B;  4F5T A;  1HK3 A;  5IIH A;  1BKE A;  2YDF A;  2Z8J A;  2BXQ A;  2DG5 A;  3FWB C;  3NVI A;  2BXI A;  4L8U A;  2BXF A;  2E0Y A;  3V08 A;  5GIP A;  2DBW A;  4HGM B;  4NAW B;  4F5S A;  3MHH B;  5IIU A;  4MBE C;  5B5T A;  4ZCG A;  1J78 A;  1BJ5 A;  3FWC C;  3WHS A;  1HK1 A;  3W1S A;  4GG2 A;  2CKX A;  2BXP A;  3B9L A;  3A73 A;  1E7I A;  1GNI A;  5ID7 A;  4ZBR A;  3SQJ A;  3V09 A;  2BXC A;  2QMC A;  2XW0 A;  4GDX A;  4LA0 A;  2BXG A;  4N3Z A;  4Z69 A;  2BXE A;  4GDL B;  4EMX A;  4DHX B;  3SIU B;  2NNW A;  1HK4 A;  3V03 A;  3M99 C;  2E0X A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...