4Z9OA

Crystal structure of human ggt1
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
342
structure length
342
Chain Sequence
DNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDAVLYMPSAPLSGPVLALILNILKGYNFSRESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISDDTTHPISYYKPEFYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Human gamma-Glutamyl Transpeptidase 1: STRUCTURES OF THE FREE ENZYME, INHIBITOR-BOUND TETRAHEDRAL TRANSITION STATES, AND GLUTAMATE-BOUND ENZYME REVEAL NOVEL MOVEMENT WITHIN THE ACTIVE SITE DURING CATALYSIS.
pubmed doi rcsb
molecule keywords Gamma-glutamyltranspeptidase 1
molecule tags Hydrolase,transferase
source organism Homo sapiens
total genus 107
structure length 342
sequence length 342
ec nomenclature ec 2.3.2.2: Gamma-glutamyltransferase.
pdb deposition date 2015-04-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.130 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z9oA02
3FNMA 4ZC6A 4ZCGA 3A75A 4Z9OA 4ZBKA 2QM6A 2V36A 2DBUA 2Z8KA 2NQOA 2E0XA 3WHRA 4OTUA 2DBXA 2Z8JA 5BPKA 4GDXA 3WHQA 5B5TA 2DBWA 2Z8IA 2E0YA 4OTTA 4GG2A 2DG5A 2QMCA 3WHSA
chains in the Genus database with same CATH superfamily
4JK4A 1GNIA 4DHXB 2XVVA 1BKEA 1E7AA 2I2ZA 1VFIA 2ROHA 3JRYA 3G9KD 1SB0A 2BXDA 2QM6A 3CX9A 2V36A 4MBEC 5GIPA 2LOQA 2Z8KA 5GIOA 1FOUA 1HK3A 3WHRA 2VDBA 4OR0A 2BXNA 1GNJA 4PO0A 3SQJA 2BXHA 1E7GA 1O9XA 2XVQA 5IIHA 2K0NA 3SIVB 1KW2A 3JQZA 2BXOA 3VQIA 4NAWB 1E78A 4GDXA 4TQ0A 2QHBA 3LU7A 3MHHB 1H9ZA 2BXIA 2DBWA 3B9LA 4FJCB 5B5TA 1HK4A 2XVWA 2OZBB 4N3ZA 4BY9C 4M70B 5ID7A 3GA9L 4GG2A 4HGMB 1N5UA 3A73A 2YDFA 2BXPA 1MIYA 1E7HA 2BXGA 3MHSB 4LA0A 3KIKA 4IW2A 2DYOA 3FNMA 2EFCA 4N0UD 5D7GA 3BPJA 1E7IA 2VUEA 2OT3A 1BJ5A 2NNWA 3FWBC 4TQ1A 2DBUA 2EFEA 1MM8A 5DBYA 3V09A 4FK5B 2BXFA 2DBXA 2VUFA 5BPKA 4L9QA 5IIXA 1AO6A 5DQFA 5IJFA 5IIUA 2XMOA 4ZBQA 4ZBRA 4LUFA 2BXQA 3V08A 1E7EA 1HK5A 4G03A 4S1YA 1KXPD 2BXLA 4LB9A 1KDXA 3PLAA 2DG5A 3W1SA 3WHSA 1TF0A 1J78A 1HK2A 1BM0A 3V03A 4E99A 3ICXA 4F5TA 3H3AA 1MIVA 1UORA 2BXMA 4IW1A 4ZCGA 4W4UB 4ZUXV 4Z9OA 2BXEA 1HK1A 3B9MA 3H37A 1H5WA 4ZBKA 3NVMA 2KWFA 4F5UA 1TXUA 3NMUA 2CKXA 4I9OA 4EMXA 2NQOA 4GDLB 4J2VA 1MA9A 4F5VA 1LNSA 4LUHA 2Z8JA 4WA6B 4G01A 3WHQA 1HA2A 4G04A 2BXKA 3TDLA 1LOTA 4GDKB 5IJ5A 4L9KA 2JUHA 2XW0A 4BKEA 2I30A 2XSIA 4OTTA 4D7XA 1MUHA 4F5SA 5GHKA 2QMCA 5IFOA 1VZSA 2LQHA 4LB2A 2DYMA 2EFHA 1E7CA 4FIPB 2LXTA 4ZC6A 2KBZA 1J7EA 3A75A 1IJGA 3GQXA 2AGHB 2BX8A 2BXAA 2EFDA 5ID9A 1E7FA 3M99C 3KJLA 2XW1A 5IJEA 3SIUB 3UIVA 5FUOA 2E0XA 2LXSA 3NVIA 2GUTA 4OTUA 4L8UA 4OT2A 2LQIA 5GINA 1JNBA 4HGKA 2AJEA 2BXCA 4N0FD 4C31B 4Z69A 4K71A 1E7BA 2BXBA 1NT2B 2Z8IA 4K2CA 4DM0A 1MIWA 2E0YA 3ECPA 1MUSA 3NVKA 5HOZA 3GQUA 3FWCC 3LU6A 2XVUA 3LU8A
chains in the Genus database with same CATH topology
4JK4A 1GNIA 4DHXB 2XVVA 1BKEA 1E7AA 2I2ZA 1VFIA 2ROHA 3JRYA 3G9KD 2BXDA 2QM6A 3CX9A 2V36A 4MBEC 5GIPA 2LOQA 2Z8KA 5GIOA 1FOUA 1HK3A 3WHRA 2VDBA 4OR0A 2BXNA 1GNJA 4PO0A 3SQJA 2BXHA 1E7GA 1O9XA 2XVQA 5IIHA 3SIVB 1KW2A 3JQZA 2BXOA 3VQIA 4NAWB 1E78A 4GDXA 4TQ0A 2QHBA 3LU7A 3MHHB 1H9ZA 2BXIA 2DBWA 3B9LA 4FJCB 5B5TA 1HK4A 2XVWA 2OZBB 4N3ZA 4BY9C 4M70B 5ID7A 3GA9L 4GG2A 4HGMB 1N5UA 3A73A 2YDFA 2BXPA 1MIYA 1E7HA 2BXGA 3MHSB 4LA0A 3KIKA 4IW2A 2DYOA 3FNMA 2EFCA 4N0UD 5D7GA 1E7IA 2VUEA 2OT3A 1BJ5A 2NNWA 3FWBC 4TQ1A 2DBUA 2EFEA 5DBYA 3V09A 4FK5B 2BXFA 2DBXA 2VUFA 5BPKA 4L9QA 5IIXA 1AO6A 5DQFA 5IJFA 5IIUA 2XMOA 4ZBQA 4ZBRA 4LUFA 2BXQA 3V08A 1E7EA 1HK5A 4G03A 4S1YA 1KXPD 2BXLA 4LB9A 3PLAA 2DG5A 3W1SA 3WHSA 1TF0A 1J78A 1HK2A 1BM0A 3V03A 4E99A 3ICXA 4F5TA 3H3AA 1MIVA 1UORA 2BXMA 4IW1A 4ZCGA 4W4UB 4ZUXV 4Z9OA 2BXEA 1HK1A 3B9MA 3H37A 1H5WA 4ZBKA 3NVMA 4F5UA 1TXUA 3NMUA 2CKXA 4EMXA 2NQOA 4GDLB 4J2VA 1MA9A 4F5VA 1LNSA 4LUHA 2Z8JA 4WA6B 4G01A 3WHQA 1HA2A 4G04A 2BXKA 3TDLA 1LOTA 4GDKB 5IJ5A 4L9KA 2JUHA 2XW0A 4BKEA 2I30A 2XSIA 4OTTA 4F5SA 5GHKA 2QMCA 5IFOA 1VZSA 4LB2A 2DYMA 2EFHA 1E7CA 4FIPB 4ZC6A 2KBZA 1J7EA 3A75A 1IJGA 3GQXA 2BX8A 2BXAA 2EFDA 5ID9A 1E7FA 3M99C 3KJLA 2XW1A 5IJEA 3SIUB 3UIVA 5FUOA 2E0XA 3NVIA 4OTUA 4L8UA 4OT2A 5GINA 1JNBA 4HGKA 2AJEA 2BXCA 4N0FD 4C31B 4Z69A 4K71A 1E7BA 2BXBA 1NT2B 2Z8IA 4K2CA 1MIWA 2E0YA 3NVKA 5HOZA 3GQUA 3FWCC 3LU6A 2XVUA 3LU8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FNM A;  4ZC6 A;  4ZCG A;  3A75 A;  4Z9O A;  4ZBK A;  2QM6 A;  2V36 A;  2DBU A;  2Z8K A;  2NQO A;  2E0X A;  3WHR A;  4OTU A;  2DBX A;  2Z8J A;  5BPK A;  4GDX A;  3WHQ A;  5B5T A;  2DBW A;  2Z8I A;  2E0Y A;  4OTT A;  4GG2 A;  2DG5 A;  2QMC A;  3WHS A; 
#chains in the Genus database with same CATH topology
 4JK4 A;  1GNI A;  4DHX B;  2XVV A;  1BKE A;  1E7A A;  2I2Z A;  1VFI A;  2ROH A;  3JRY A;  3G9K D;  1SB0 A;  2BXD A;  2QM6 A;  3CX9 A;  2V36 A;  4MBE C;  5GIP A;  2LOQ A;  2Z8K A;  5GIO A;  1FOU A;  1HK3 A;  3WHR A;  2VDB A;  4OR0 A;  2BXN A;  1GNJ A;  4PO0 A;  3SQJ A;  2BXH A;  1E7G A;  1O9X A;  2XVQ A;  5IIH A;  2K0N A;  3SIV B;  1KW2 A;  3JQZ A;  2BXO A;  3VQI A;  4NAW B;  1E78 A;  4GDX A;  4TQ0 A;  2QHB A;  3LU7 A;  3MHH B;  1H9Z A;  2BXI A;  2DBW A;  3B9L A;  4FJC B;  5B5T A;  1HK4 A;  2XVW A;  2OZB B;  4N3Z A;  4BY9 C;  4M70 B;  5ID7 A;  3GA9 L;  4GG2 A;  4HGM B;  1N5U A;  3A73 A;  2YDF A;  2BXP A;  1MIY A;  1E7H A;  2BXG A;  3MHS B;  4LA0 A;  3KIK A;  4IW2 A;  2DYO A;  3FNM A;  2EFC A;  4N0U D;  5D7G A;  3BPJ A;  1E7I A;  2VUE A;  2OT3 A;  1BJ5 A;  2NNW A;  3FWB C;  4TQ1 A;  2DBU A;  2EFE A;  1MM8 A;  5DBY A;  3V09 A;  4FK5 B;  2BXF A;  2DBX A;  2VUF A;  5BPK A;  4L9Q A;  5IIX A;  1AO6 A;  5DQF A;  5IJF A;  5IIU A;  2XMO A;  4ZBQ A;  4ZBR A;  4LUF A;  2BXQ A;  3V08 A;  1E7E A;  1HK5 A;  4G03 A;  4S1Y A;  1KXP D;  2BXL A;  4LB9 A;  1KDX A;  3PLA A;  2DG5 A;  3W1S A;  3WHS A;  1TF0 A;  1J78 A;  1HK2 A;  1BM0 A;  3V03 A;  4E99 A;  3ICX A;  4F5T A;  3H3A A;  1MIV A;  1UOR A;  2BXM A;  4IW1 A;  4ZCG A;  4W4U B;  4ZUX V;  4Z9O A;  2BXE A;  1HK1 A;  3B9M A;  3H37 A;  1H5W A;  4ZBK A;  3NVM A;  2KWF A;  4F5U A;  1TXU A;  3NMU A;  2CKX A;  4I9O A;  4EMX A;  2NQO A;  4GDL B;  4J2V A;  1MA9 A;  4F5V A;  1LNS A;  4LUH A;  2Z8J A;  4WA6 B;  4G01 A;  3WHQ A;  1HA2 A;  4G04 A;  2BXK A;  3TDL A;  1LOT A;  4GDK B;  5IJ5 A;  4L9K A;  2JUH A;  2XW0 A;  4BKE A;  2I30 A;  2XSI A;  4OTT A;  4D7X A;  1MUH A;  4F5S A;  5GHK A;  2QMC A;  5IFO A;  1VZS A;  2LQH A;  4LB2 A;  2DYM A;  2EFH A;  1E7C A;  4FIP B;  2LXT A;  4ZC6 A;  2KBZ A;  1J7E A;  3A75 A;  1IJG A;  3GQX A;  2AGH B;  2BX8 A;  2BXA A;  2EFD A;  5ID9 A;  1E7F A;  3M99 C;  3KJL A;  2XW1 A;  5IJE A;  3SIU B;  3UIV A;  5FUO A;  2E0X A;  2LXS A;  3NVI A;  2GUT A;  4OTU A;  4L8U A;  4OT2 A;  2LQI A;  5GIN A;  1JNB A;  4HGK A;  2AJE A;  2BXC A;  4N0F D;  4C31 B;  4Z69 A;  4K71 A;  1E7B A;  2BXB A;  1NT2 B;  2Z8I A;  4K2C A;  4DM0 A;  1MIW A;  2E0Y A;  3ECP A;  1MUS A;  3NVK A;  5HOZ A;  3GQU A;  3FWC C;  3LU6 A;  2XVU A;  3LU8 A; 
#chains in the Genus database with same CATH homology
 4JK4 A;  1GNI A;  4DHX B;  2XVV A;  1BKE A;  1E7A A;  2I2Z A;  1VFI A;  2ROH A;  3JRY A;  3G9K D;  2BXD A;  2QM6 A;  3CX9 A;  2V36 A;  4MBE C;  5GIP A;  2LOQ A;  2Z8K A;  5GIO A;  1FOU A;  1HK3 A;  3WHR A;  2VDB A;  4OR0 A;  2BXN A;  1GNJ A;  4PO0 A;  3SQJ A;  2BXH A;  1E7G A;  1O9X A;  2XVQ A;  5IIH A;  3SIV B;  1KW2 A;  3JQZ A;  2BXO A;  3VQI A;  4NAW B;  1E78 A;  4GDX A;  4TQ0 A;  2QHB A;  3LU7 A;  3MHH B;  1H9Z A;  2BXI A;  2DBW A;  3B9L A;  4FJC B;  5B5T A;  1HK4 A;  2XVW A;  2OZB B;  4N3Z A;  4BY9 C;  4M70 B;  5ID7 A;  3GA9 L;  4GG2 A;  4HGM B;  1N5U A;  3A73 A;  2YDF A;  2BXP A;  1MIY A;  1E7H A;  2BXG A;  3MHS B;  4LA0 A;  3KIK A;  4IW2 A;  2DYO A;  3FNM A;  2EFC A;  4N0U D;  5D7G A;  1E7I A;  2VUE A;  2OT3 A;  1BJ5 A;  2NNW A;  3FWB C;  4TQ1 A;  2DBU A;  2EFE A;  5DBY A;  3V09 A;  4FK5 B;  2BXF A;  2DBX A;  2VUF A;  5BPK A;  4L9Q A;  5IIX A;  1AO6 A;  5DQF A;  5IJF A;  5IIU A;  2XMO A;  4ZBQ A;  4ZBR A;  4LUF A;  2BXQ A;  3V08 A;  1E7E A;  1HK5 A;  4G03 A;  4S1Y A;  1KXP D;  2BXL A;  4LB9 A;  3PLA A;  2DG5 A;  3W1S A;  3WHS A;  1TF0 A;  1J78 A;  1HK2 A;  1BM0 A;  3V03 A;  4E99 A;  3ICX A;  4F5T A;  3H3A A;  1MIV A;  1UOR A;  2BXM A;  4IW1 A;  4ZCG A;  4W4U B;  4ZUX V;  4Z9O A;  2BXE A;  1HK1 A;  3B9M A;  3H37 A;  1H5W A;  4ZBK A;  3NVM A;  4F5U A;  1TXU A;  3NMU A;  2CKX A;  4EMX A;  2NQO A;  4GDL B;  4J2V A;  1MA9 A;  4F5V A;  1LNS A;  4LUH A;  2Z8J A;  4WA6 B;  4G01 A;  3WHQ A;  1HA2 A;  4G04 A;  2BXK A;  3TDL A;  1LOT A;  4GDK B;  5IJ5 A;  4L9K A;  2JUH A;  2XW0 A;  4BKE A;  2I30 A;  2XSI A;  4OTT A;  4F5S A;  5GHK A;  2QMC A;  5IFO A;  1VZS A;  4LB2 A;  2DYM A;  2EFH A;  1E7C A;  4FIP B;  4ZC6 A;  2KBZ A;  1J7E A;  3A75 A;  1IJG A;  3GQX A;  2BX8 A;  2BXA A;  2EFD A;  5ID9 A;  1E7F A;  3M99 C;  3KJL A;  2XW1 A;  5IJE A;  3SIU B;  3UIV A;  5FUO A;  2E0X A;  3NVI A;  4OTU A;  4L8U A;  4OT2 A;  5GIN A;  1JNB A;  4HGK A;  2AJE A;  2BXC A;  4N0F D;  4C31 B;  4Z69 A;  4K71 A;  1E7B A;  2BXB A;  1NT2 B;  2Z8I A;  4K2C A;  1MIW A;  2E0Y A;  3NVK A;  5HOZ A;  3GQU A;  3FWC C;  3LU6 A;  2XVU A;  3LU8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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