4Z9OA

Crystal structure of human ggt1
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
342
structure length
342
Chain Sequence
DNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDAVLYMPSAPLSGPVLALILNILKGYNFSRESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISDDTTHPISYYKPEFYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Gamma-glutamyltranspeptidase 1
publication title Human gamma-Glutamyl Transpeptidase 1: STRUCTURES OF THE FREE ENZYME, INHIBITOR-BOUND TETRAHEDRAL TRANSITION STATES, AND GLUTAMATE-BOUND ENZYME REVEAL NOVEL MOVEMENT WITHIN THE ACTIVE SITE DURING CATALYSIS.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase,transferase
total genus 107
structure length 342
sequence length 342
ec nomenclature ec 2.3.2.2: Gamma-glutamyltransferase.
pdb deposition date 2015-04-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.130 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4z9oA02
4Z9OA 2Z8JA 2Z8KA 2NQOA 2DBUA 3FNMA 4OTTA 2QM6A 2Z8IA 2V36A 2E0YA 2QMCA 4GG2A 2DG5A 2E0XA 4GDXA 3WHQA 3WHSA 3A75A 2DBWA 4ZBKA 3WHRA 4ZC6A 4OTUA 4ZCGA 5BPKA 2DBXA 5B5TA
chains in the Genus database with same CATH superfamily
3LU8A 3GQUA 5GHKA 3UIVA 5DQFA 4ZBQA 5IJFA 3KIKA 1NT2B 2KWFA 2LXSA 2XW0A 3V08A 2K0NA 3PLAA 1MM8A 2XMOA 2DBUA 1MA9A 1E7AA 1E7IA 2I2ZA 3NVKA 2EFHA 2XSIA 1GNIA 2XVUA 4F5VA 4IW2A 2OZBB 1HA2A 4S1YA 4OT2A 4D7XA 2BXHA 3H3AA 2BXNA 4N3ZA 2BXLA 3WHSA 1SB0A 3ICXA 1LNSA 2XW1A 1H5WA 2BXKA 4HGKA 1MIYA 4DM0A 2BXMA 4LUHA 4M70B 3B9LA 5FUOA 1MUHA 4MBEC 1UORA 1E78A 2LOQA 2DBXA 1KDXA 2BXGA 4GDKB 4Z9OA 2BX8A 2BXIA 1H9ZA 5DBYA 2Z8KA 4G04A 3V03A 4Z69A 2XVQA 2BXEA 2NQOA 2AGHB 1E7CA 1O9XA 1FOUA 4OTTA 5IJ5A 4JK4A 2QM6A 4BKEA 2CKXA 1KXPD 1IJGA 1E7FA 2ROHA 2Z8IA 3BPJA 2I30A 4L9QA 2BXOA 2OT3A 5IIXA 2V36A 2E0YA 2XVWA 1MIWA 2BXFA 3NVMA 1N5UA 4OR0A 3V09A 2E0XA 3MHSB 4I9OA 2JUHA 2XVVA 3WHQA 1BKEA 4FIPB 2QHBA 4G03A 2GUTA 2BXBA 3W1SA 1E7HA 2BXDA 3LU6A 4ZCGA 1KW2A 5HOZA 3SQJA 3VQIA 1HK5A 4LUFA 1HK1A 4F5TA 2BXQA 5B5TA 2DYOA 4IW1A 4F5SA 4WA6B 4F5UA 3FWBC 4LB2A 3JRYA 4N0UD 3ECPA 1MUSA 5GIOA 5GIPA 2VDBA 2LQIA 5IFOA 2VUEA 5GINA 4HGMB 4N0FD 2BXCA 1HK4A 4EMXA 4L9KA 4LB9A 1VFIA 3G9KD 3KJLA 1BM0A 4ZUXV 1BJ5A 2BXAA 2QMCA 4GG2A 2DG5A 1HK3A 4GDXA 4NAWB 2NNWA 1VZSA 2DYMA 3NVIA 5IIHA 4OTUA 5IJEA 4E99A 1TXUA 5D7GA 1MIVA 1JNBA 3GQXA 3H37A 4W4UB 2KBZA 3B9MA 3GA9L 4FK5B 4K2CA 4GDLB 2LXTA 2Z8JA 1LOTA 4ZBRA 5IIUA 1E7GA 4L8UA 3SIUB 3NMUA 3SIVB 2VUFA 4TQ1A 2EFCA 3M99C 3FNMA 1E7EA 2YDFA 5ID9A 4BY9C 1GNJA 2LQHA 4TQ0A 3MHHB 4K71A 4FJCB 1AO6A 3FWCC 2EFEA 3CX9A 1TF0A 4PO0A 4J2VA 1HK2A 3TDLA 3A73A 3LU7A 4DHXB 2BXPA 4C31B 4LA0A 3A75A 2DBWA 4ZBKA 3WHRA 2AJEA 3JQZA 4ZC6A 5ID7A 4G01A 5BPKA 1E7BA 2EFDA 1J7EA 1J78A
chains in the Genus database with same CATH topology
3LU8A 3GQUA 5GHKA 3UIVA 5DQFA 4ZBQA 5IJFA 3KIKA 1NT2B 2XW0A 3V08A 3PLAA 3NVKA 2XMOA 2DBUA 1MA9A 2I2ZA 1E7AA 1E7IA 2EFHA 2XSIA 1GNIA 2XVUA 4F5VA 4IW2A 2OZBB 1HA2A 4S1YA 4OT2A 2BXHA 3H3AA 2BXNA 4N3ZA 2BXLA 3WHSA 3ICXA 1LNSA 2XW1A 1H5WA 2BXKA 4HGKA 1MIYA 2BXMA 4LUHA 4M70B 3B9LA 5FUOA 4MBEC 1UORA 1E78A 2LOQA 2DBXA 2BXGA 4GDKB 4Z9OA 2BX8A 2BXIA 1H9ZA 5DBYA 2Z8KA 4G04A 3V03A 4Z69A 2XVQA 2BXEA 2NQOA 1E7CA 1O9XA 1FOUA 4OTTA 5IJ5A 4JK4A 2QM6A 4BKEA 2CKXA 1KXPD 1IJGA 1E7FA 2ROHA 2Z8IA 4L9QA 2I30A 5IIXA 2BXOA 2OT3A 5GIOA 2V36A 2E0YA 2XVWA 1MIWA 2BXFA 3NVMA 1N5UA 4OR0A 3V09A 2E0XA 3MHSB 3WHQA 2JUHA 2XVVA 2QHBA 1BKEA 4FIPB 4G03A 2BXBA 3W1SA 1E7HA 2BXDA 3LU6A 4ZCGA 1KW2A 5HOZA 3SQJA 3VQIA 1HK5A 4LUFA 1HK1A 4F5TA 2BXQA 5B5TA 2DYOA 4IW1A 4F5SA 4WA6B 4F5UA 3FWBC 4LB2A 3JRYA 4N0UD 5GIPA 2VDBA 5IFOA 2VUEA 5GINA 4HGMB 4N0FD 2BXCA 1HK4A 4EMXA 4L9KA 4LB9A 1VFIA 3G9KD 3KJLA 1BM0A 4ZUXV 1BJ5A 2BXAA 2QMCA 4GG2A 2DG5A 1HK3A 4GDXA 4NAWB 2NNWA 1VZSA 2DYMA 3NVIA 5IIHA 4OTUA 5IJEA 4E99A 1TXUA 5D7GA 1MIVA 1JNBA 3GQXA 3H37A 4W4UB 2KBZA 3B9MA 3GA9L 4FK5B 4K2CA 4GDLB 2Z8JA 4ZBRA 1LOTA 5IIUA 1E7GA 4L8UA 3SIUB 3NMUA 3SIVB 2VUFA 4TQ1A 2EFCA 3M99C 3FNMA 1E7EA 2YDFA 5ID9A 4BY9C 1GNJA 4TQ0A 3MHHB 4K71A 4FJCB 1AO6A 3FWCC 2EFEA 3CX9A 1TF0A 4PO0A 4J2VA 1HK2A 3TDLA 3A73A 3LU7A 4DHXB 2BXPA 4C31B 4LA0A 3A75A 2DBWA 4ZBKA 3WHRA 2AJEA 3JQZA 4ZC6A 5ID7A 4G01A 5BPKA 1E7BA 2EFDA 1J7EA 1J78A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Z9O A;  2Z8J A;  2Z8K A;  2NQO A;  2DBU A;  3FNM A;  4OTT A;  2QM6 A;  2Z8I A;  2V36 A;  2E0Y A;  2QMC A;  4GG2 A;  2DG5 A;  2E0X A;  4GDX A;  3WHQ A;  3WHS A;  3A75 A;  2DBW A;  4ZBK A;  3WHR A;  4ZC6 A;  4OTU A;  4ZCG A;  5BPK A;  2DBX A;  5B5T A; 
#chains in the Genus database with same CATH topology
 3LU8 A;  3GQU A;  5GHK A;  3UIV A;  5DQF A;  4ZBQ A;  5IJF A;  3KIK A;  1NT2 B;  2KWF A;  2LXS A;  2XW0 A;  3V08 A;  2K0N A;  3PLA A;  1MM8 A;  2XMO A;  2DBU A;  1MA9 A;  1E7A A;  1E7I A;  2I2Z A;  3NVK A;  2EFH A;  2XSI A;  1GNI A;  2XVU A;  4F5V A;  4IW2 A;  2OZB B;  1HA2 A;  4S1Y A;  4OT2 A;  4D7X A;  2BXH A;  3H3A A;  2BXN A;  4N3Z A;  2BXL A;  3WHS A;  1SB0 A;  3ICX A;  1LNS A;  2XW1 A;  1H5W A;  2BXK A;  4HGK A;  1MIY A;  4DM0 A;  2BXM A;  4LUH A;  4M70 B;  3B9L A;  5FUO A;  1MUH A;  4MBE C;  1UOR A;  1E78 A;  2LOQ A;  2DBX A;  1KDX A;  2BXG A;  4GDK B;  4Z9O A;  2BX8 A;  2BXI A;  1H9Z A;  5DBY A;  2Z8K A;  4G04 A;  3V03 A;  4Z69 A;  2XVQ A;  2BXE A;  2NQO A;  2AGH B;  1E7C A;  1O9X A;  1FOU A;  4OTT A;  5IJ5 A;  4JK4 A;  2QM6 A;  4BKE A;  2CKX A;  1KXP D;  1IJG A;  1E7F A;  2ROH A;  2Z8I A;  3BPJ A;  2I30 A;  4L9Q A;  2BXO A;  2OT3 A;  5IIX A;  2V36 A;  2E0Y A;  2XVW A;  1MIW A;  2BXF A;  3NVM A;  1N5U A;  4OR0 A;  3V09 A;  2E0X A;  3MHS B;  4I9O A;  2JUH A;  2XVV A;  3WHQ A;  1BKE A;  4FIP B;  2QHB A;  4G03 A;  2GUT A;  2BXB A;  3W1S A;  1E7H A;  2BXD A;  3LU6 A;  4ZCG A;  1KW2 A;  5HOZ A;  3SQJ A;  3VQI A;  1HK5 A;  4LUF A;  1HK1 A;  4F5T A;  2BXQ A;  5B5T A;  2DYO A;  4IW1 A;  4F5S A;  4WA6 B;  4F5U A;  3FWB C;  4LB2 A;  3JRY A;  4N0U D;  3ECP A;  1MUS A;  5GIO A;  5GIP A;  2VDB A;  2LQI A;  5IFO A;  2VUE A;  5GIN A;  4HGM B;  4N0F D;  2BXC A;  1HK4 A;  4EMX A;  4L9K A;  4LB9 A;  1VFI A;  3G9K D;  3KJL A;  1BM0 A;  4ZUX V;  1BJ5 A;  2BXA A;  2QMC A;  4GG2 A;  2DG5 A;  1HK3 A;  4GDX A;  4NAW B;  2NNW A;  1VZS A;  2DYM A;  3NVI A;  5IIH A;  4OTU A;  5IJE A;  4E99 A;  1TXU A;  5D7G A;  1MIV A;  1JNB A;  3GQX A;  3H37 A;  4W4U B;  2KBZ A;  3B9M A;  3GA9 L;  4FK5 B;  4K2C A;  4GDL B;  2LXT A;  2Z8J A;  1LOT A;  4ZBR A;  5IIU A;  1E7G A;  4L8U A;  3SIU B;  3NMU A;  3SIV B;  2VUF A;  4TQ1 A;  2EFC A;  3M99 C;  3FNM A;  1E7E A;  2YDF A;  5ID9 A;  4BY9 C;  1GNJ A;  2LQH A;  4TQ0 A;  3MHH B;  4K71 A;  4FJC B;  1AO6 A;  3FWC C;  2EFE A;  3CX9 A;  1TF0 A;  4PO0 A;  4J2V A;  1HK2 A;  3TDL A;  3A73 A;  3LU7 A;  4DHX B;  2BXP A;  4C31 B;  4LA0 A;  3A75 A;  2DBW A;  4ZBK A;  3WHR A;  2AJE A;  3JQZ A;  4ZC6 A;  5ID7 A;  4G01 A;  5BPK A;  1E7B A;  2EFD A;  1J7E A;  1J78 A; 
#chains in the Genus database with same CATH homology
 3LU8 A;  3GQU A;  5GHK A;  3UIV A;  5DQF A;  4ZBQ A;  5IJF A;  3KIK A;  1NT2 B;  2XW0 A;  3V08 A;  3PLA A;  3NVK A;  2XMO A;  2DBU A;  1MA9 A;  2I2Z A;  1E7A A;  1E7I A;  2EFH A;  2XSI A;  1GNI A;  2XVU A;  4F5V A;  4IW2 A;  2OZB B;  1HA2 A;  4S1Y A;  4OT2 A;  2BXH A;  3H3A A;  2BXN A;  4N3Z A;  2BXL A;  3WHS A;  3ICX A;  1LNS A;  2XW1 A;  1H5W A;  2BXK A;  4HGK A;  1MIY A;  2BXM A;  4LUH A;  4M70 B;  3B9L A;  5FUO A;  4MBE C;  1UOR A;  1E78 A;  2LOQ A;  2DBX A;  2BXG A;  4GDK B;  4Z9O A;  2BX8 A;  2BXI A;  1H9Z A;  5DBY A;  2Z8K A;  4G04 A;  3V03 A;  4Z69 A;  2XVQ A;  2BXE A;  2NQO A;  1E7C A;  1O9X A;  1FOU A;  4OTT A;  5IJ5 A;  4JK4 A;  2QM6 A;  4BKE A;  2CKX A;  1KXP D;  1IJG A;  1E7F A;  2ROH A;  2Z8I A;  4L9Q A;  2I30 A;  5IIX A;  2BXO A;  2OT3 A;  5GIO A;  2V36 A;  2E0Y A;  2XVW A;  1MIW A;  2BXF A;  3NVM A;  1N5U A;  4OR0 A;  3V09 A;  2E0X A;  3MHS B;  3WHQ A;  2JUH A;  2XVV A;  2QHB A;  1BKE A;  4FIP B;  4G03 A;  2BXB A;  3W1S A;  1E7H A;  2BXD A;  3LU6 A;  4ZCG A;  1KW2 A;  5HOZ A;  3SQJ A;  3VQI A;  1HK5 A;  4LUF A;  1HK1 A;  4F5T A;  2BXQ A;  5B5T A;  2DYO A;  4IW1 A;  4F5S A;  4WA6 B;  4F5U A;  3FWB C;  4LB2 A;  3JRY A;  4N0U D;  5GIP A;  2VDB A;  5IFO A;  2VUE A;  5GIN A;  4HGM B;  4N0F D;  2BXC A;  1HK4 A;  4EMX A;  4L9K A;  4LB9 A;  1VFI A;  3G9K D;  3KJL A;  1BM0 A;  4ZUX V;  1BJ5 A;  2BXA A;  2QMC A;  4GG2 A;  2DG5 A;  1HK3 A;  4GDX A;  4NAW B;  2NNW A;  1VZS A;  2DYM A;  3NVI A;  5IIH A;  4OTU A;  5IJE A;  4E99 A;  1TXU A;  5D7G A;  1MIV A;  1JNB A;  3GQX A;  3H37 A;  4W4U B;  2KBZ A;  3B9M A;  3GA9 L;  4FK5 B;  4K2C A;  4GDL B;  2Z8J A;  4ZBR A;  1LOT A;  5IIU A;  1E7G A;  4L8U A;  3SIU B;  3NMU A;  3SIV B;  2VUF A;  4TQ1 A;  2EFC A;  3M99 C;  3FNM A;  1E7E A;  2YDF A;  5ID9 A;  4BY9 C;  1GNJ A;  4TQ0 A;  3MHH B;  4K71 A;  4FJC B;  1AO6 A;  3FWC C;  2EFE A;  3CX9 A;  1TF0 A;  4PO0 A;  4J2V A;  1HK2 A;  3TDL A;  3A73 A;  3LU7 A;  4DHX B;  2BXP A;  4C31 B;  4LA0 A;  3A75 A;  2DBW A;  4ZBK A;  3WHR A;  2AJE A;  3JQZ A;  4ZC6 A;  5ID7 A;  4G01 A;  5BPK A;  1E7B A;  2EFD A;  1J7E A;  1J78 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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