4ZBKA

Crystal structure of human ggt1 in complex with ggstop inhibitor
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
342
structure length
342
Chain Sequence
DNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDAVLYMPSAPLSGPVLALILNILKGYNFSRESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISDDTTHPISYYKPEFYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Gamma-glutamyltranspeptidase 1
publication title Human gamma-Glutamyl Transpeptidase 1: STRUCTURES OF THE FREE ENZYME, INHIBITOR-BOUND TETRAHEDRAL TRANSITION STATES, AND GLUTAMATE-BOUND ENZYME REVEAL NOVEL MOVEMENT WITHIN THE ACTIVE SITE DURING CATALYSIS.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase/hydrolase inhibitor
total genus 109
structure length 342
sequence length 342
ec nomenclature ec 2.3.2.2: Gamma-glutamyltransferase.
pdb deposition date 2015-04-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.130 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4zbkA02
3WHQA 2QMCA 4GDXA 4ZCGA 3A75A 2Z8JA 2DG5A 2DBWA 2Z8KA 2DBXA 4GG2A 3WHSA 2QM6A 2DBUA 5BPKA 2NQOA 3FNMA 4ZBKA 5B5TA 4Z9OA 2E0XA 4OTTA 2V36A 3WHRA 4OTUA 2Z8IA 2E0YA 4ZC6A
chains in the Genus database with same CATH superfamily
4MBEC 2EFHA 2BXLA 3V03A 1BKEA 4DM0A 2BXOA 2BXNA 2I2ZA 4G03A 3G9KD 2BXAA 1TXUA 2ROHA 2JUHA 1E7EA 2DG5A 4FJCB 4LUHA 3M99C 3SQJA 2DBWA 2DYOA 2EFDA 4L9KA 2DBXA 4E99A 5HOZA 1E7FA 3WHSA 2BXGA 4K71A 1LOTA 4ZBRA 2BXBA 3PLAA 3FWCC 5BPKA 4BY9C 1N5UA 2AJEA 2AGHB 4N0UD 2XVUA 3FNMA 4FK5B 2VUFA 4LB9A 2XVVA 1KDXA 1JNBA 5GIOA 2BXPA 1E7AA 2KWFA 1MIWA 3B9MA 2E0XA 3ICXA 3JRYA 4GDLB 3TDLA 3JQZA 1LNSA 4G04A 2XVQA 5DQFA 3GQXA 1BJ5A 3KIKA 3WHRA 4OTUA 5IIUA 5IIXA 2E0YA 1UORA 4IW1A 4TQ0A 1E7GA 1VZSA 4GDXA 2GUTA 2LXSA 5FUOA 2NNWA 3NVMA 1O9XA 2LQIA 3A75A 1HK2A 1E78A 4ZBQA 5GHKA 2BXCA 4J2VA 4LUFA 5IFOA 3B9LA 4K2CA 2BXKA 4BKEA 1H5WA 2BXEA 4I9OA 2DBUA 3LU7A 2NQOA 3A73A 3BPJA 2BXIA 4PO0A 4F5TA 2BXDA 5IJ5A 2BXMA 2K0NA 1MIVA 3FWBC 1HA2A 4DHXB 1VFIA 1H9ZA 4TQ1A 3GA9L 1NT2B 2V36A 4D7XA 1IJGA 5GINA 3SIUB 5GIPA 2Z8IA 4ZC6A 1E7IA 3WHQA 4ZCGA 2EFCA 3LU8A 2LXTA 1J78A 5ID9A 4M70B 4F5SA 4N0FD 2Z8KA 4LA0A 4F5UA 4IW2A 1SB0A 3MHHB 3NMUA 1HK1A 4S1YA 1MUSA 4G01A 4N3ZA 1KXPD 3ECPA 2BX8A 3H37A 3KJLA 4ZUXV 3V08A 4EMXA 2QHBA 4W4UB 4ZBKA 2XSIA 4C31B 1GNIA 2LQHA 2BXQA 3W1SA 2XW0A 3GQUA 2XW1A 2XMOA 1E7CA 3NVKA 3SIVB 2QMCA 1MUHA 2LOQA 1E7BA 3H3AA 4JK4A 2OT3A 4FIPB 2Z8JA 1MA9A 2KBZA 2CKXA 3VQIA 3NVIA 5D7GA 2BXHA 4GG2A 5IIHA 5ID7A 3MHSB 4OR0A 4HGKA 4L8UA 5IJEA 2QM6A 1MM8A 4Z69A 1HK5A 2EFEA 4GDKB 1MIYA 1BM0A 2XVWA 4OT2A 3CX9A 5IJFA 1AO6A 3UIVA 1J7EA 2I30A 5B5TA 5DBYA 2OZBB 4L9QA 4HGMB 1HK3A 2VDBA 4NAWB 4Z9OA 1KW2A 4F5VA 3LU6A 1TF0A 4OTTA 1FOUA 1GNJA 2VUEA 1E7HA 2BXFA 2YDFA 2DYMA 1HK4A 3V09A 4LB2A 4WA6B
chains in the Genus database with same CATH topology
4MBEC 2EFHA 2BXLA 3V03A 1BKEA 2BXOA 2BXNA 2I2ZA 4G03A 3G9KD 2BXAA 1TXUA 2ROHA 2JUHA 1E7EA 2DG5A 4FJCB 4LUHA 3M99C 3SQJA 2DBWA 2DYOA 2EFDA 4L9KA 2DBXA 4E99A 5HOZA 1E7FA 3WHSA 2BXGA 4K71A 1LOTA 4ZBRA 2BXBA 3PLAA 3FWCC 5BPKA 4BY9C 1N5UA 2AJEA 4N0UD 2XVUA 3FNMA 4FK5B 2VUFA 4LB9A 2XVVA 1JNBA 5GIOA 2BXPA 1E7AA 3B9MA 1MIWA 3ICXA 2E0XA 3JRYA 4GDLB 3TDLA 3JQZA 1LNSA 4G04A 2XVQA 5DQFA 3GQXA 1BJ5A 3KIKA 3WHRA 4OTUA 5IIUA 5IIXA 2E0YA 1UORA 4IW1A 4TQ0A 1E7GA 1VZSA 4GDXA 5FUOA 2NNWA 3NVMA 1O9XA 3A75A 1HK2A 1E78A 4ZBQA 5GHKA 2BXCA 4J2VA 4LUFA 5IFOA 3B9LA 4K2CA 2BXKA 4BKEA 1H5WA 2BXEA 2DBUA 3LU7A 2NQOA 3A73A 2BXIA 4PO0A 4F5TA 2BXDA 5IJ5A 2BXMA 1MIVA 3FWBC 1HA2A 4DHXB 1VFIA 1H9ZA 4TQ1A 3GA9L 1NT2B 2V36A 5GINA 1IJGA 3SIUB 5GIPA 2Z8IA 4ZC6A 1E7IA 3WHQA 4ZCGA 2EFCA 3LU8A 1J78A 5ID9A 4M70B 4F5SA 4N0FD 2Z8KA 4LA0A 4F5UA 4IW2A 3MHHB 3NMUA 1HK1A 4S1YA 4G01A 4N3ZA 1KXPD 2BX8A 3H37A 3KJLA 4ZUXV 3V08A 4EMXA 2QHBA 4W4UB 4ZBKA 2XSIA 4C31B 1GNIA 2BXQA 3W1SA 2XW0A 3GQUA 2XW1A 2XMOA 1E7CA 3NVKA 3SIVB 2QMCA 2LOQA 1E7BA 3H3AA 4JK4A 2OT3A 4FIPB 2Z8JA 1MA9A 2KBZA 2CKXA 3VQIA 3NVIA 5D7GA 2BXHA 4GG2A 5IIHA 5ID7A 3MHSB 4OR0A 4HGKA 4L8UA 5IJEA 2QM6A 4Z69A 1HK5A 2EFEA 4GDKB 1MIYA 1BM0A 2XVWA 4OT2A 3CX9A 5IJFA 1AO6A 3UIVA 1J7EA 2I30A 5B5TA 5DBYA 2OZBB 4L9QA 4HGMB 1HK3A 2VDBA 4NAWB 4Z9OA 1KW2A 4F5VA 3LU6A 1TF0A 4OTTA 1FOUA 1GNJA 2VUEA 1E7HA 2BXFA 2YDFA 2DYMA 1HK4A 3V09A 4LB2A 4WA6B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WHQ A;  2QMC A;  4GDX A;  4ZCG A;  3A75 A;  2Z8J A;  2DG5 A;  2DBW A;  2Z8K A;  2DBX A;  4GG2 A;  3WHS A;  2QM6 A;  2DBU A;  5BPK A;  2NQO A;  3FNM A;  4ZBK A;  5B5T A;  4Z9O A;  2E0X A;  4OTT A;  2V36 A;  3WHR A;  4OTU A;  2Z8I A;  2E0Y A;  4ZC6 A; 
#chains in the Genus database with same CATH topology
 4MBE C;  2EFH A;  2BXL A;  3V03 A;  1BKE A;  4DM0 A;  2BXO A;  2BXN A;  2I2Z A;  4G03 A;  3G9K D;  2BXA A;  1TXU A;  2ROH A;  2JUH A;  1E7E A;  2DG5 A;  4FJC B;  4LUH A;  3M99 C;  3SQJ A;  2DBW A;  2DYO A;  2EFD A;  4L9K A;  2DBX A;  4E99 A;  5HOZ A;  1E7F A;  3WHS A;  2BXG A;  4K71 A;  1LOT A;  4ZBR A;  2BXB A;  3PLA A;  3FWC C;  5BPK A;  4BY9 C;  1N5U A;  2AJE A;  2AGH B;  4N0U D;  2XVU A;  3FNM A;  4FK5 B;  2VUF A;  4LB9 A;  2XVV A;  1KDX A;  1JNB A;  5GIO A;  2BXP A;  1E7A A;  2KWF A;  1MIW A;  3B9M A;  2E0X A;  3ICX A;  3JRY A;  4GDL B;  3TDL A;  3JQZ A;  1LNS A;  4G04 A;  2XVQ A;  5DQF A;  3GQX A;  1BJ5 A;  3KIK A;  3WHR A;  4OTU A;  5IIU A;  5IIX A;  2E0Y A;  1UOR A;  4IW1 A;  4TQ0 A;  1E7G A;  1VZS A;  4GDX A;  2GUT A;  2LXS A;  5FUO A;  2NNW A;  3NVM A;  1O9X A;  2LQI A;  3A75 A;  1HK2 A;  1E78 A;  4ZBQ A;  5GHK A;  2BXC A;  4J2V A;  4LUF A;  5IFO A;  3B9L A;  4K2C A;  2BXK A;  4BKE A;  1H5W A;  2BXE A;  4I9O A;  2DBU A;  3LU7 A;  2NQO A;  3A73 A;  3BPJ A;  2BXI A;  4PO0 A;  4F5T A;  2BXD A;  5IJ5 A;  2BXM A;  2K0N A;  1MIV A;  3FWB C;  1HA2 A;  4DHX B;  1VFI A;  1H9Z A;  4TQ1 A;  3GA9 L;  1NT2 B;  2V36 A;  4D7X A;  1IJG A;  5GIN A;  3SIU B;  5GIP A;  2Z8I A;  4ZC6 A;  1E7I A;  3WHQ A;  4ZCG A;  2EFC A;  3LU8 A;  2LXT A;  1J78 A;  5ID9 A;  4M70 B;  4F5S A;  4N0F D;  2Z8K A;  4LA0 A;  4F5U A;  4IW2 A;  1SB0 A;  3MHH B;  3NMU A;  1HK1 A;  4S1Y A;  1MUS A;  4G01 A;  4N3Z A;  1KXP D;  3ECP A;  2BX8 A;  3H37 A;  3KJL A;  4ZUX V;  3V08 A;  4EMX A;  2QHB A;  4W4U B;  4ZBK A;  2XSI A;  4C31 B;  1GNI A;  2LQH A;  2BXQ A;  3W1S A;  2XW0 A;  3GQU A;  2XW1 A;  2XMO A;  1E7C A;  3NVK A;  3SIV B;  2QMC A;  1MUH A;  2LOQ A;  1E7B A;  3H3A A;  4JK4 A;  2OT3 A;  4FIP B;  2Z8J A;  1MA9 A;  2KBZ A;  2CKX A;  3VQI A;  3NVI A;  5D7G A;  2BXH A;  4GG2 A;  5IIH A;  5ID7 A;  3MHS B;  4OR0 A;  4HGK A;  4L8U A;  5IJE A;  2QM6 A;  1MM8 A;  4Z69 A;  1HK5 A;  2EFE A;  4GDK B;  1MIY A;  1BM0 A;  2XVW A;  4OT2 A;  3CX9 A;  5IJF A;  1AO6 A;  3UIV A;  1J7E A;  2I30 A;  5B5T A;  5DBY A;  2OZB B;  4L9Q A;  4HGM B;  1HK3 A;  2VDB A;  4NAW B;  4Z9O A;  1KW2 A;  4F5V A;  3LU6 A;  1TF0 A;  4OTT A;  1FOU A;  1GNJ A;  2VUE A;  1E7H A;  2BXF A;  2YDF A;  2DYM A;  1HK4 A;  3V09 A;  4LB2 A;  4WA6 B; 
#chains in the Genus database with same CATH homology
 4MBE C;  2EFH A;  2BXL A;  3V03 A;  1BKE A;  2BXO A;  2BXN A;  2I2Z A;  4G03 A;  3G9K D;  2BXA A;  1TXU A;  2ROH A;  2JUH A;  1E7E A;  2DG5 A;  4FJC B;  4LUH A;  3M99 C;  3SQJ A;  2DBW A;  2DYO A;  2EFD A;  4L9K A;  2DBX A;  4E99 A;  5HOZ A;  1E7F A;  3WHS A;  2BXG A;  4K71 A;  1LOT A;  4ZBR A;  2BXB A;  3PLA A;  3FWC C;  5BPK A;  4BY9 C;  1N5U A;  2AJE A;  4N0U D;  2XVU A;  3FNM A;  4FK5 B;  2VUF A;  4LB9 A;  2XVV A;  1JNB A;  5GIO A;  2BXP A;  1E7A A;  3B9M A;  1MIW A;  3ICX A;  2E0X A;  3JRY A;  4GDL B;  3TDL A;  3JQZ A;  1LNS A;  4G04 A;  2XVQ A;  5DQF A;  3GQX A;  1BJ5 A;  3KIK A;  3WHR A;  4OTU A;  5IIU A;  5IIX A;  2E0Y A;  1UOR A;  4IW1 A;  4TQ0 A;  1E7G A;  1VZS A;  4GDX A;  5FUO A;  2NNW A;  3NVM A;  1O9X A;  3A75 A;  1HK2 A;  1E78 A;  4ZBQ A;  5GHK A;  2BXC A;  4J2V A;  4LUF A;  5IFO A;  3B9L A;  4K2C A;  2BXK A;  4BKE A;  1H5W A;  2BXE A;  2DBU A;  3LU7 A;  2NQO A;  3A73 A;  2BXI A;  4PO0 A;  4F5T A;  2BXD A;  5IJ5 A;  2BXM A;  1MIV A;  3FWB C;  1HA2 A;  4DHX B;  1VFI A;  1H9Z A;  4TQ1 A;  3GA9 L;  1NT2 B;  2V36 A;  5GIN A;  1IJG A;  3SIU B;  5GIP A;  2Z8I A;  4ZC6 A;  1E7I A;  3WHQ A;  4ZCG A;  2EFC A;  3LU8 A;  1J78 A;  5ID9 A;  4M70 B;  4F5S A;  4N0F D;  2Z8K A;  4LA0 A;  4F5U A;  4IW2 A;  3MHH B;  3NMU A;  1HK1 A;  4S1Y A;  4G01 A;  4N3Z A;  1KXP D;  2BX8 A;  3H37 A;  3KJL A;  4ZUX V;  3V08 A;  4EMX A;  2QHB A;  4W4U B;  4ZBK A;  2XSI A;  4C31 B;  1GNI A;  2BXQ A;  3W1S A;  2XW0 A;  3GQU A;  2XW1 A;  2XMO A;  1E7C A;  3NVK A;  3SIV B;  2QMC A;  2LOQ A;  1E7B A;  3H3A A;  4JK4 A;  2OT3 A;  4FIP B;  2Z8J A;  1MA9 A;  2KBZ A;  2CKX A;  3VQI A;  3NVI A;  5D7G A;  2BXH A;  4GG2 A;  5IIH A;  5ID7 A;  3MHS B;  4OR0 A;  4HGK A;  4L8U A;  5IJE A;  2QM6 A;  4Z69 A;  1HK5 A;  2EFE A;  4GDK B;  1MIY A;  1BM0 A;  2XVW A;  4OT2 A;  3CX9 A;  5IJF A;  1AO6 A;  3UIV A;  1J7E A;  2I30 A;  5B5T A;  5DBY A;  2OZB B;  4L9Q A;  4HGM B;  1HK3 A;  2VDB A;  4NAW B;  4Z9O A;  1KW2 A;  4F5V A;  3LU6 A;  1TF0 A;  4OTT A;  1FOU A;  1GNJ A;  2VUE A;  1E7H A;  2BXF A;  2YDF A;  2DYM A;  1HK4 A;  3V09 A;  4LB2 A;  4WA6 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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