4ZBKA

Crystal structure of human ggt1 in complex with ggstop inhibitor
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
342
structure length
342
Chain Sequence
DNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDAVLYMPSAPLSGPVLALILNILKGYNFSRESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISDDTTHPISYYKPEFYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Human gamma-Glutamyl Transpeptidase 1: STRUCTURES OF THE FREE ENZYME, INHIBITOR-BOUND TETRAHEDRAL TRANSITION STATES, AND GLUTAMATE-BOUND ENZYME REVEAL NOVEL MOVEMENT WITHIN THE ACTIVE SITE DURING CATALYSIS.
pubmed doi rcsb
molecule keywords Gamma-glutamyltranspeptidase 1
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
total genus 109
structure length 342
sequence length 342
ec nomenclature ec 2.3.2.2: Gamma-glutamyltransferase.
pdb deposition date 2015-04-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.130 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4zbkA02
3WHSA 2NQOA 4ZBKA 2E0XA 5BPKA 3WHRA 2V36A 2E0YA 4OTTA 4OTUA 2Z8JA 4ZC6A 4GG2A 2DBUA 3WHQA 2QM6A 2DBWA 4GDXA 4Z9OA 2QMCA 2DBXA 2Z8KA 4ZCGA 2DG5A 3FNMA 3A75A 2Z8IA 5B5TA
chains in the Genus database with same CATH superfamily
4HGKA 1VFIA 2NQOA 4F5UA 3W1SA 3KIKA 1HK5A 2E0XA 1E7GA 3H37A 4NAWB 4MBEC 1NT2B 1O9XA 2BXIA 4BKEA 4DHXB 4D7XA 4FJCB 3LU6A 1J78A 1GNJA 3NVIA 4OTTA 3MHHB 4M70B 4OTUA 5DQFA 2DBUA 2BXFA 4GG2A 5FUOA 3MHSB 4N0FD 2VUFA 5IJFA 4GDXA 3ECPA 3GQXA 1E7AA 1J7EA 2BX8A 3V03A 2OZBB 2XW0A 2KBZA 3SIUB 4W4UB 1HK1A 5IJ5A 1LNSA 1MIYA 2EFCA 2Z8KA 4F5SA 3KJLA 2K0NA 4TQ1A 1KXPD 2EFHA 3G9KD 1E7IA 1N5UA 2XVUA 2CKXA 3GQUA 2E0YA 2LOQA 2Z8IA 4N3ZA 5GIPA 3GA9L 4G01A 4L9QA 4LB9A 5IFOA 2LXSA 3JRYA 5GHKA 4PO0A 2XVQA 4IW1A 2BXNA 2KWFA 5BPKA 3A73A 4IW2A 1BKEA 4FK5B 2OT3A 2XVVA 2VUEA 1AO6A 1E7EA 4J2VA 1HK4A 1TF0A 2BXHA 5DBYA 2BXQA 3VQIA 2V36A 4HGMB 4E99A 4OT2A 4K2CA 2Z8JA 1VZSA 4L8UA 3WHQA 3FWBC 1TXUA 1H5WA 2BXCA 1LOTA 1SB0A 1E7FA 1FOUA 5IIXA 3LU7A 2EFDA 4F5TA 1H9ZA 2BXDA 1KW2A 2XSIA 4TQ0A 3FNMA 4GDKB 5HOZA 3SIVB 4N0UD 2AJEA 1MUSA 3V08A 4G04A 2JUHA 5B5TA 3CX9A 4ZBKA 2BXOA 2XW1A 1E7HA 1MIVA 4DM0A 4ZBQA 3NVKA 4FIPB 2AGHB 1HK2A 4S1YA 3NVMA 2EFEA 4F5VA 5ID9A 1E7CA 5IIHA 3BPJA 4ZC6A 2LQIA 3FWCC 3H3AA 4K71A 1E7BA 2QM6A 4BY9C 2DBWA 3LU8A 4C31B 1HK3A 2XMOA 3UIVA 4Z9OA 1MIWA 4ZBRA 1MUHA 2DYMA 3B9LA 1E78A 4OR0A 3TDLA 2BXAA 2DBXA 4I9OA 1IJGA 1KDXA 1MA9A 3A75A 5ID7A 3JQZA 1JNBA 5GINA 3WHSA 1HA2A 3SQJA 2BXGA 2I30A 2LQHA 2ROHA 3PLAA 4ZUXV 1BM0A 4GDLB 5GIOA 4Z69A 2XVWA 2BXPA 4G03A 2I2ZA 4LB2A 3WHRA 1BJ5A 4LA0A 1GNIA 4LUHA 3M99C 2DYOA 5D7GA 4L9KA 2BXLA 2GUTA 1UORA 3NMUA 1MM8A 4EMXA 5IIUA 2QHBA 2QMCA 2LXTA 4JK4A 4WA6B 3B9MA 2BXBA 3V09A 2YDFA 4ZCGA 2DG5A 5IJEA 4LUFA 2BXMA 2BXKA 3ICXA 2NNWA 2VDBA 2BXEA
chains in the Genus database with same CATH topology
4HGKA 1VFIA 2NQOA 4F5UA 3W1SA 3KIKA 1HK5A 2E0XA 1E7GA 3H37A 4NAWB 4MBEC 1NT2B 1O9XA 2BXIA 4BKEA 4DHXB 4FJCB 3LU6A 1J78A 1GNJA 3NVIA 4OTTA 3MHHB 4M70B 4OTUA 5DQFA 2DBUA 2BXFA 4GG2A 5FUOA 3MHSB 4N0FD 2VUFA 5IJFA 4GDXA 3GQXA 1E7AA 1J7EA 2BX8A 3V03A 2OZBB 2XW0A 2KBZA 3SIUB 4W4UB 1HK1A 5IJ5A 1LNSA 1MIYA 2EFCA 2Z8KA 4F5SA 3KJLA 4TQ1A 1KXPD 2EFHA 3G9KD 1E7IA 1N5UA 2XVUA 2CKXA 3GQUA 2E0YA 2LOQA 2Z8IA 4N3ZA 5GIPA 3GA9L 4G01A 4L9QA 4LB9A 5IFOA 3JRYA 5GHKA 4PO0A 2XVQA 4IW1A 2BXNA 5BPKA 3A73A 4IW2A 1BKEA 4FK5B 2OT3A 2XVVA 2VUEA 1AO6A 1E7EA 4J2VA 1HK4A 1TF0A 2BXHA 5DBYA 2BXQA 3VQIA 2V36A 4HGMB 4E99A 4OT2A 4K2CA 2Z8JA 1VZSA 4L8UA 3WHQA 3FWBC 1TXUA 1H5WA 2BXCA 1LOTA 1E7FA 1FOUA 5IIXA 3LU7A 2EFDA 4F5TA 1H9ZA 2BXDA 1KW2A 2XSIA 4TQ0A 3FNMA 4GDKB 5HOZA 3SIVB 4N0UD 2AJEA 3V08A 4G04A 2JUHA 5B5TA 3CX9A 4ZBKA 2BXOA 2XW1A 1E7HA 1MIVA 4ZBQA 3NVKA 4FIPB 1HK2A 4S1YA 3NVMA 2EFEA 4F5VA 5ID9A 1E7CA 5IIHA 4ZC6A 3FWCC 3H3AA 4K71A 1E7BA 2QM6A 4BY9C 2DBWA 3LU8A 4C31B 1HK3A 2XMOA 3UIVA 4Z9OA 1MIWA 4ZBRA 2DYMA 3B9LA 1E78A 4OR0A 3TDLA 2BXAA 2DBXA 1IJGA 1MA9A 3A75A 5ID7A 3JQZA 1JNBA 5GINA 3WHSA 1HA2A 3SQJA 2BXGA 2I30A 2ROHA 3PLAA 4ZUXV 1BM0A 4GDLB 5GIOA 4Z69A 2XVWA 2BXPA 4G03A 2I2ZA 4LB2A 3WHRA 1BJ5A 4LA0A 1GNIA 4LUHA 3M99C 2DYOA 5D7GA 4L9KA 2BXLA 1UORA 3NMUA 4EMXA 5IIUA 2QHBA 2QMCA 4JK4A 4WA6B 3B9MA 2BXBA 3V09A 2YDFA 4ZCGA 2DG5A 5IJEA 4LUFA 2BXMA 2BXKA 3ICXA 2NNWA 2VDBA 2BXEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WHS A;  2NQO A;  4ZBK A;  2E0X A;  5BPK A;  3WHR A;  2V36 A;  2E0Y A;  4OTT A;  4OTU A;  2Z8J A;  4ZC6 A;  4GG2 A;  2DBU A;  3WHQ A;  2QM6 A;  2DBW A;  4GDX A;  4Z9O A;  2QMC A;  2DBX A;  2Z8K A;  4ZCG A;  2DG5 A;  3FNM A;  3A75 A;  2Z8I A;  5B5T A; 
#chains in the Genus database with same CATH topology
 4HGK A;  1VFI A;  2NQO A;  4F5U A;  3W1S A;  3KIK A;  1HK5 A;  2E0X A;  1E7G A;  3H37 A;  4NAW B;  4MBE C;  1NT2 B;  1O9X A;  2BXI A;  4BKE A;  4DHX B;  4D7X A;  4FJC B;  3LU6 A;  1J78 A;  1GNJ A;  3NVI A;  4OTT A;  3MHH B;  4M70 B;  4OTU A;  5DQF A;  2DBU A;  2BXF A;  4GG2 A;  5FUO A;  3MHS B;  4N0F D;  2VUF A;  5IJF A;  4GDX A;  3ECP A;  3GQX A;  1E7A A;  1J7E A;  2BX8 A;  3V03 A;  2OZB B;  2XW0 A;  2KBZ A;  3SIU B;  4W4U B;  1HK1 A;  5IJ5 A;  1LNS A;  1MIY A;  2EFC A;  2Z8K A;  4F5S A;  3KJL A;  2K0N A;  4TQ1 A;  1KXP D;  2EFH A;  3G9K D;  1E7I A;  1N5U A;  2XVU A;  2CKX A;  3GQU A;  2E0Y A;  2LOQ A;  2Z8I A;  4N3Z A;  5GIP A;  3GA9 L;  4G01 A;  4L9Q A;  4LB9 A;  5IFO A;  2LXS A;  3JRY A;  5GHK A;  4PO0 A;  2XVQ A;  4IW1 A;  2BXN A;  2KWF A;  5BPK A;  3A73 A;  4IW2 A;  1BKE A;  4FK5 B;  2OT3 A;  2XVV A;  2VUE A;  1AO6 A;  1E7E A;  4J2V A;  1HK4 A;  1TF0 A;  2BXH A;  5DBY A;  2BXQ A;  3VQI A;  2V36 A;  4HGM B;  4E99 A;  4OT2 A;  4K2C A;  2Z8J A;  1VZS A;  4L8U A;  3WHQ A;  3FWB C;  1TXU A;  1H5W A;  2BXC A;  1LOT A;  1SB0 A;  1E7F A;  1FOU A;  5IIX A;  3LU7 A;  2EFD A;  4F5T A;  1H9Z A;  2BXD A;  1KW2 A;  2XSI A;  4TQ0 A;  3FNM A;  4GDK B;  5HOZ A;  3SIV B;  4N0U D;  2AJE A;  1MUS A;  3V08 A;  4G04 A;  2JUH A;  5B5T A;  3CX9 A;  4ZBK A;  2BXO A;  2XW1 A;  1E7H A;  1MIV A;  4DM0 A;  4ZBQ A;  3NVK A;  4FIP B;  2AGH B;  1HK2 A;  4S1Y A;  3NVM A;  2EFE A;  4F5V A;  5ID9 A;  1E7C A;  5IIH A;  3BPJ A;  4ZC6 A;  2LQI A;  3FWC C;  3H3A A;  4K71 A;  1E7B A;  2QM6 A;  4BY9 C;  2DBW A;  3LU8 A;  4C31 B;  1HK3 A;  2XMO A;  3UIV A;  4Z9O A;  1MIW A;  4ZBR A;  1MUH A;  2DYM A;  3B9L A;  1E78 A;  4OR0 A;  3TDL A;  2BXA A;  2DBX A;  4I9O A;  1IJG A;  1KDX A;  1MA9 A;  3A75 A;  5ID7 A;  3JQZ A;  1JNB A;  5GIN A;  3WHS A;  1HA2 A;  3SQJ A;  2BXG A;  2I30 A;  2LQH A;  2ROH A;  3PLA A;  4ZUX V;  1BM0 A;  4GDL B;  5GIO A;  4Z69 A;  2XVW A;  2BXP A;  4G03 A;  2I2Z A;  4LB2 A;  3WHR A;  1BJ5 A;  4LA0 A;  1GNI A;  4LUH A;  3M99 C;  2DYO A;  5D7G A;  4L9K A;  2BXL A;  2GUT A;  1UOR A;  3NMU A;  1MM8 A;  4EMX A;  5IIU A;  2QHB A;  2QMC A;  2LXT A;  4JK4 A;  4WA6 B;  3B9M A;  2BXB A;  3V09 A;  2YDF A;  4ZCG A;  2DG5 A;  5IJE A;  4LUF A;  2BXM A;  2BXK A;  3ICX A;  2NNW A;  2VDB A;  2BXE A; 
#chains in the Genus database with same CATH homology
 4HGK A;  1VFI A;  2NQO A;  4F5U A;  3W1S A;  3KIK A;  1HK5 A;  2E0X A;  1E7G A;  3H37 A;  4NAW B;  4MBE C;  1NT2 B;  1O9X A;  2BXI A;  4BKE A;  4DHX B;  4FJC B;  3LU6 A;  1J78 A;  1GNJ A;  3NVI A;  4OTT A;  3MHH B;  4M70 B;  4OTU A;  5DQF A;  2DBU A;  2BXF A;  4GG2 A;  5FUO A;  3MHS B;  4N0F D;  2VUF A;  5IJF A;  4GDX A;  3GQX A;  1E7A A;  1J7E A;  2BX8 A;  3V03 A;  2OZB B;  2XW0 A;  2KBZ A;  3SIU B;  4W4U B;  1HK1 A;  5IJ5 A;  1LNS A;  1MIY A;  2EFC A;  2Z8K A;  4F5S A;  3KJL A;  4TQ1 A;  1KXP D;  2EFH A;  3G9K D;  1E7I A;  1N5U A;  2XVU A;  2CKX A;  3GQU A;  2E0Y A;  2LOQ A;  2Z8I A;  4N3Z A;  5GIP A;  3GA9 L;  4G01 A;  4L9Q A;  4LB9 A;  5IFO A;  3JRY A;  5GHK A;  4PO0 A;  2XVQ A;  4IW1 A;  2BXN A;  5BPK A;  3A73 A;  4IW2 A;  1BKE A;  4FK5 B;  2OT3 A;  2XVV A;  2VUE A;  1AO6 A;  1E7E A;  4J2V A;  1HK4 A;  1TF0 A;  2BXH A;  5DBY A;  2BXQ A;  3VQI A;  2V36 A;  4HGM B;  4E99 A;  4OT2 A;  4K2C A;  2Z8J A;  1VZS A;  4L8U A;  3WHQ A;  3FWB C;  1TXU A;  1H5W A;  2BXC A;  1LOT A;  1E7F A;  1FOU A;  5IIX A;  3LU7 A;  2EFD A;  4F5T A;  1H9Z A;  2BXD A;  1KW2 A;  2XSI A;  4TQ0 A;  3FNM A;  4GDK B;  5HOZ A;  3SIV B;  4N0U D;  2AJE A;  3V08 A;  4G04 A;  2JUH A;  5B5T A;  3CX9 A;  4ZBK A;  2BXO A;  2XW1 A;  1E7H A;  1MIV A;  4ZBQ A;  3NVK A;  4FIP B;  1HK2 A;  4S1Y A;  3NVM A;  2EFE A;  4F5V A;  5ID9 A;  1E7C A;  5IIH A;  4ZC6 A;  3FWC C;  3H3A A;  4K71 A;  1E7B A;  2QM6 A;  4BY9 C;  2DBW A;  3LU8 A;  4C31 B;  1HK3 A;  2XMO A;  3UIV A;  4Z9O A;  1MIW A;  4ZBR A;  2DYM A;  3B9L A;  1E78 A;  4OR0 A;  3TDL A;  2BXA A;  2DBX A;  1IJG A;  1MA9 A;  3A75 A;  5ID7 A;  3JQZ A;  1JNB A;  5GIN A;  3WHS A;  1HA2 A;  3SQJ A;  2BXG A;  2I30 A;  2ROH A;  3PLA A;  4ZUX V;  1BM0 A;  4GDL B;  5GIO A;  4Z69 A;  2XVW A;  2BXP A;  4G03 A;  2I2Z A;  4LB2 A;  3WHR A;  1BJ5 A;  4LA0 A;  1GNI A;  4LUH A;  3M99 C;  2DYO A;  5D7G A;  4L9K A;  2BXL A;  1UOR A;  3NMU A;  4EMX A;  5IIU A;  2QHB A;  2QMC A;  4JK4 A;  4WA6 B;  3B9M A;  2BXB A;  3V09 A;  2YDF A;  4ZCG A;  2DG5 A;  5IJE A;  4LUF A;  2BXM A;  2BXK A;  3ICX A;  2NNW A;  2VDB A;  2BXE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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