4ZC6A

Crystal structure of human ggt1 in complex with serine borate
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
342
structure length
342
Chain Sequence
DNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDAVLYMPSAPLSGPVLALILNILKGYNFSRESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISDDTTHPISYYKPEFYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Gamma-glutamyltranspeptidase 1 heavy chain
publication title Human gamma-Glutamyl Transpeptidase 1: STRUCTURES OF THE FREE ENZYME, INHIBITOR-BOUND TETRAHEDRAL TRANSITION STATES, AND GLUTAMATE-BOUND ENZYME REVEAL NOVEL MOVEMENT WITHIN THE ACTIVE SITE DURING CATALYSIS.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase/hydrolase inhibitor
total genus 110
structure length 342
sequence length 342
ec nomenclature ec 2.3.2.2: Gamma-glutamyltransferase.
pdb deposition date 2015-04-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.130 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4zc6A02
2DBUA 4GG2A 2E0YA 2DG5A 4GDXA 2Z8IA 4Z9OA 3A75A 3WHQA 2V36A 2NQOA 2QM6A 3WHRA 4OTUA 4ZBKA 2E0XA 2DBWA 4ZCGA 5B5TA 2QMCA 5BPKA 2Z8KA 4ZC6A 2Z8JA 3WHSA 3FNMA 4OTTA 2DBXA
chains in the Genus database with same CATH superfamily
4GG2A 4ZBQA 3JRYA 1E78A 2YDFA 1E7IA 2XSIA 4BY9C 4LB9A 5D7GA 3MHSB 4DM0A 4Z69A 4OT2A 3FWCC 1O9XA 3A75A 4FIPB 5HOZA 1N5UA 3WHQA 2NNWA 1J7EA 2BXFA 1TF0A 2NQOA 3CX9A 4WA6B 5GINA 1E7AA 1UORA 1HA2A 3SIVB 1MUSA 2XVWA 3UIVA 1KDXA 2BXBA 4TQ1A 5GHKA 3NVKA 2VDBA 4BKEA 2E0XA 2DBWA 2GUTA 2LXSA 4N0FD 4C31B 4HGKA 3W1SA 4F5VA 2CKXA 4NAWB 1E7CA 2KWFA 3LU7A 3FNMA 3M99C 4OTTA 2DBXA 3BPJA 3NVMA 2K0NA 2BXDA 4HGMB 1MIWA 4N3ZA 4PO0A 2EFDA 3H3AA 4LUHA 2OT3A 2LQIA 1TXUA 5IFOA 1LOTA 1E7GA 5DBYA 1MIYA 2EFHA 2Z8IA 2XMOA 2XW0A 4GDLB 3V09A 1HK2A 2V36A 4D7XA 2BXEA 3B9LA 5IIXA 3MHHB 3V03A 4OTUA 5GIOA 1HK3A 1MIVA 3GQXA 5FUOA 4TQ0A 4L9KA 3SIUB 1GNIA 4K71A 4E99A 4ZBRA 3KIKA 5B5TA 3ECPA 5BPKA 1E7FA 2BXOA 4LB2A 5IJEA 1AO6A 2BXKA 1J78A 4M70B 4OR0A 3G9KD 2XVUA 1VZSA 5IIHA 1HK1A 3VQIA 4W4UB 4GDXA 5ID9A 3LU6A 2JUHA 1HK5A 1VFIA 4LUFA 1FOUA 1E7HA 4Z9OA 1KXPD 4N0UD 3PLAA 2AJEA 2I30A 4F5SA 2BXPA 1H5WA 3NMUA 1BM0A 2DYOA 2BXNA 3V08A 2OZBB 3NVIA 2BX8A 1MM8A 2XW1A 1E7BA 3H37A 2BXHA 4F5TA 3KJLA 2I2ZA 4JK4A 1H9ZA 1NT2B 1LNSA 3FWBC 1BKEA 4S1YA 2QMCA 1HK4A 4MBEC 3LU8A 4DHXB 2QHBA 2VUFA 2Z8JA 2XVVA 2BXLA 1SB0A 4FJCB 4L9QA 2XVQA 5GIPA 2DBUA 5IJ5A 4F5UA 2E0YA 2EFEA 2BXGA 3SQJA 3ICXA 4K2CA 1IJGA 2DG5A 3GQUA 2LXTA 2AGHB 5DQFA 4IW1A 1JNBA 5ID7A 2DYMA 2BXQA 3TDLA 4L8UA 1E7EA 2KBZA 4J2VA 2BXAA 2VUEA 2QM6A 1BJ5A 3WHRA 3A73A 4GDKB 5IJFA 2BXIA 1KW2A 4FK5B 4LA0A 4EMXA 1GNJA 2LOQA 2EFCA 3B9MA 4ZBKA 3JQZA 4ZCGA 2BXMA 2BXCA 4IW2A 4ZUXV 2ROHA 2LQHA 3GA9L 1MA9A 2Z8KA 4G03A 4G01A 4ZC6A 5IIUA 1MUHA 3WHSA 4I9OA 4G04A
chains in the Genus database with same CATH topology
4GG2A 4ZBQA 3JRYA 1E78A 2YDFA 1E7IA 2XSIA 4BY9C 4LB9A 5D7GA 3MHSB 4Z69A 4OT2A 3FWCC 1O9XA 3A75A 4FIPB 5HOZA 1N5UA 3WHQA 2NNWA 1J7EA 2BXFA 1TF0A 2NQOA 3CX9A 4WA6B 5GINA 1E7AA 1UORA 1HA2A 3SIVB 2XVWA 3UIVA 2BXBA 4TQ1A 5GHKA 2VDBA 4BKEA 2E0XA 2DBWA 4C31B 4N0FD 4F5VA 4HGKA 3W1SA 2CKXA 4NAWB 1E7CA 3LU7A 3FNMA 3M99C 4OTTA 2DBXA 3NVMA 2BXDA 4HGMB 1MIWA 4N3ZA 4PO0A 2EFDA 3H3AA 4LUHA 2OT3A 1TXUA 5IFOA 1LOTA 1E7GA 5DBYA 1MIYA 2EFHA 2Z8IA 2XMOA 2XW0A 4GDLB 3V09A 1HK2A 2V36A 2BXEA 3B9LA 5IIXA 3MHHB 3V03A 4OTUA 5GIOA 1HK3A 1MIVA 3GQXA 5FUOA 4TQ0A 4L9KA 3SIUB 1GNIA 4K71A 4E99A 4ZBRA 3KIKA 5B5TA 5BPKA 1E7FA 2BXOA 4LB2A 5IJEA 1AO6A 2BXKA 1J78A 4M70B 4OR0A 3G9KD 2XVUA 1VZSA 5IIHA 1HK1A 3VQIA 4W4UB 4GDXA 5ID9A 3LU6A 2JUHA 1HK5A 1VFIA 4LUFA 1FOUA 1E7HA 4Z9OA 1KXPD 4N0UD 3PLAA 2AJEA 2I30A 4F5SA 2BXPA 1H5WA 3NMUA 1BM0A 2DYOA 2BXNA 3V08A 2OZBB 3NVIA 2BX8A 2XW1A 1E7BA 3H37A 2BXHA 4F5TA 3KJLA 2I2ZA 4JK4A 1H9ZA 1NT2B 1LNSA 3FWBC 1BKEA 4S1YA 2QMCA 1HK4A 4MBEC 3LU8A 4DHXB 2QHBA 2VUFA 2Z8JA 2XVVA 2BXLA 5GIPA 4FJCB 4L9QA 2XVQA 2DBUA 5IJ5A 4F5UA 2E0YA 2EFEA 2BXGA 3SQJA 3ICXA 4K2CA 1IJGA 2DG5A 3GQUA 5DQFA 4IW1A 1JNBA 5ID7A 2DYMA 2BXQA 3TDLA 4L8UA 1E7EA 2KBZA 4J2VA 2BXAA 2VUEA 2QM6A 1BJ5A 3WHRA 3A73A 4GDKB 5IJFA 2BXIA 1KW2A 4FK5B 4LA0A 4EMXA 1GNJA 2LOQA 2EFCA 3B9MA 4ZBKA 3JQZA 4ZCGA 2BXMA 2BXCA 4IW2A 4ZUXV 2ROHA 3GA9L 4G03A 1MA9A 2Z8KA 5IIUA 4G01A 4ZC6A 3WHSA 3NVKA 4G04A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DBU A;  4GG2 A;  2E0Y A;  2DG5 A;  4GDX A;  2Z8I A;  4Z9O A;  3A75 A;  3WHQ A;  2V36 A;  2NQO A;  2QM6 A;  3WHR A;  4OTU A;  4ZBK A;  2E0X A;  2DBW A;  4ZCG A;  5B5T A;  2QMC A;  5BPK A;  2Z8K A;  4ZC6 A;  2Z8J A;  3WHS A;  3FNM A;  4OTT A;  2DBX A; 
#chains in the Genus database with same CATH topology
 4GG2 A;  4ZBQ A;  3JRY A;  1E78 A;  2YDF A;  1E7I A;  2XSI A;  4BY9 C;  4LB9 A;  5D7G A;  3MHS B;  4DM0 A;  4Z69 A;  4OT2 A;  3FWC C;  1O9X A;  3A75 A;  4FIP B;  5HOZ A;  1N5U A;  3WHQ A;  2NNW A;  1J7E A;  2BXF A;  1TF0 A;  2NQO A;  3CX9 A;  4WA6 B;  5GIN A;  1E7A A;  1UOR A;  1HA2 A;  3SIV B;  1MUS A;  2XVW A;  3UIV A;  1KDX A;  2BXB A;  4TQ1 A;  5GHK A;  3NVK A;  2VDB A;  4BKE A;  2E0X A;  2DBW A;  2GUT A;  2LXS A;  4N0F D;  4C31 B;  4HGK A;  3W1S A;  4F5V A;  2CKX A;  4NAW B;  1E7C A;  2KWF A;  3LU7 A;  3FNM A;  3M99 C;  4OTT A;  2DBX A;  3BPJ A;  3NVM A;  2K0N A;  2BXD A;  4HGM B;  1MIW A;  4N3Z A;  4PO0 A;  2EFD A;  3H3A A;  4LUH A;  2OT3 A;  2LQI A;  1TXU A;  5IFO A;  1LOT A;  1E7G A;  5DBY A;  1MIY A;  2EFH A;  2Z8I A;  2XMO A;  2XW0 A;  4GDL B;  3V09 A;  1HK2 A;  2V36 A;  4D7X A;  2BXE A;  3B9L A;  5IIX A;  3MHH B;  3V03 A;  4OTU A;  5GIO A;  1HK3 A;  1MIV A;  3GQX A;  5FUO A;  4TQ0 A;  4L9K A;  3SIU B;  1GNI A;  4K71 A;  4E99 A;  4ZBR A;  3KIK A;  5B5T A;  3ECP A;  5BPK A;  1E7F A;  2BXO A;  4LB2 A;  5IJE A;  1AO6 A;  2BXK A;  1J78 A;  4M70 B;  4OR0 A;  3G9K D;  2XVU A;  1VZS A;  5IIH A;  1HK1 A;  3VQI A;  4W4U B;  4GDX A;  5ID9 A;  3LU6 A;  2JUH A;  1HK5 A;  1VFI A;  4LUF A;  1FOU A;  1E7H A;  4Z9O A;  1KXP D;  4N0U D;  3PLA A;  2AJE A;  2I30 A;  4F5S A;  2BXP A;  1H5W A;  3NMU A;  1BM0 A;  2DYO A;  2BXN A;  3V08 A;  2OZB B;  3NVI A;  2BX8 A;  1MM8 A;  2XW1 A;  1E7B A;  3H37 A;  2BXH A;  4F5T A;  3KJL A;  2I2Z A;  4JK4 A;  1H9Z A;  1NT2 B;  1LNS A;  3FWB C;  1BKE A;  4S1Y A;  2QMC A;  1HK4 A;  4MBE C;  3LU8 A;  4DHX B;  2QHB A;  2VUF A;  2Z8J A;  2XVV A;  2BXL A;  1SB0 A;  4FJC B;  4L9Q A;  2XVQ A;  5GIP A;  2DBU A;  5IJ5 A;  4F5U A;  2E0Y A;  2EFE A;  2BXG A;  3SQJ A;  3ICX A;  4K2C A;  1IJG A;  2DG5 A;  3GQU A;  2LXT A;  2AGH B;  5DQF A;  4IW1 A;  1JNB A;  5ID7 A;  2DYM A;  2BXQ A;  3TDL A;  4L8U A;  1E7E A;  2KBZ A;  4J2V A;  2BXA A;  2VUE A;  2QM6 A;  1BJ5 A;  3WHR A;  3A73 A;  4GDK B;  5IJF A;  2BXI A;  1KW2 A;  4FK5 B;  4LA0 A;  4EMX A;  1GNJ A;  2LOQ A;  2EFC A;  3B9M A;  4ZBK A;  3JQZ A;  4ZCG A;  2BXM A;  2BXC A;  4IW2 A;  4ZUX V;  2ROH A;  2LQH A;  3GA9 L;  1MA9 A;  2Z8K A;  4G03 A;  4G01 A;  4ZC6 A;  5IIU A;  1MUH A;  3WHS A;  4I9O A;  4G04 A; 
#chains in the Genus database with same CATH homology
 4GG2 A;  4ZBQ A;  3JRY A;  1E78 A;  2YDF A;  1E7I A;  2XSI A;  4BY9 C;  4LB9 A;  5D7G A;  3MHS B;  4Z69 A;  4OT2 A;  3FWC C;  1O9X A;  3A75 A;  4FIP B;  5HOZ A;  1N5U A;  3WHQ A;  2NNW A;  1J7E A;  2BXF A;  1TF0 A;  2NQO A;  3CX9 A;  4WA6 B;  5GIN A;  1E7A A;  1UOR A;  1HA2 A;  3SIV B;  2XVW A;  3UIV A;  2BXB A;  4TQ1 A;  5GHK A;  2VDB A;  4BKE A;  2E0X A;  2DBW A;  4C31 B;  4N0F D;  4F5V A;  4HGK A;  3W1S A;  2CKX A;  4NAW B;  1E7C A;  3LU7 A;  3FNM A;  3M99 C;  4OTT A;  2DBX A;  3NVM A;  2BXD A;  4HGM B;  1MIW A;  4N3Z A;  4PO0 A;  2EFD A;  3H3A A;  4LUH A;  2OT3 A;  1TXU A;  5IFO A;  1LOT A;  1E7G A;  5DBY A;  1MIY A;  2EFH A;  2Z8I A;  2XMO A;  2XW0 A;  4GDL B;  3V09 A;  1HK2 A;  2V36 A;  2BXE A;  3B9L A;  5IIX A;  3MHH B;  3V03 A;  4OTU A;  5GIO A;  1HK3 A;  1MIV A;  3GQX A;  5FUO A;  4TQ0 A;  4L9K A;  3SIU B;  1GNI A;  4K71 A;  4E99 A;  4ZBR A;  3KIK A;  5B5T A;  5BPK A;  1E7F A;  2BXO A;  4LB2 A;  5IJE A;  1AO6 A;  2BXK A;  1J78 A;  4M70 B;  4OR0 A;  3G9K D;  2XVU A;  1VZS A;  5IIH A;  1HK1 A;  3VQI A;  4W4U B;  4GDX A;  5ID9 A;  3LU6 A;  2JUH A;  1HK5 A;  1VFI A;  4LUF A;  1FOU A;  1E7H A;  4Z9O A;  1KXP D;  4N0U D;  3PLA A;  2AJE A;  2I30 A;  4F5S A;  2BXP A;  1H5W A;  3NMU A;  1BM0 A;  2DYO A;  2BXN A;  3V08 A;  2OZB B;  3NVI A;  2BX8 A;  2XW1 A;  1E7B A;  3H37 A;  2BXH A;  4F5T A;  3KJL A;  2I2Z A;  4JK4 A;  1H9Z A;  1NT2 B;  1LNS A;  3FWB C;  1BKE A;  4S1Y A;  2QMC A;  1HK4 A;  4MBE C;  3LU8 A;  4DHX B;  2QHB A;  2VUF A;  2Z8J A;  2XVV A;  2BXL A;  5GIP A;  4FJC B;  4L9Q A;  2XVQ A;  2DBU A;  5IJ5 A;  4F5U A;  2E0Y A;  2EFE A;  2BXG A;  3SQJ A;  3ICX A;  4K2C A;  1IJG A;  2DG5 A;  3GQU A;  5DQF A;  4IW1 A;  1JNB A;  5ID7 A;  2DYM A;  2BXQ A;  3TDL A;  4L8U A;  1E7E A;  2KBZ A;  4J2V A;  2BXA A;  2VUE A;  2QM6 A;  1BJ5 A;  3WHR A;  3A73 A;  4GDK B;  5IJF A;  2BXI A;  1KW2 A;  4FK5 B;  4LA0 A;  4EMX A;  1GNJ A;  2LOQ A;  2EFC A;  3B9M A;  4ZBK A;  3JQZ A;  4ZCG A;  2BXM A;  2BXC A;  4IW2 A;  4ZUX V;  2ROH A;  3GA9 L;  4G03 A;  1MA9 A;  2Z8K A;  5IIU A;  4G01 A;  4ZC6 A;  3WHS A;  3NVK A;  4G04 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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