4ZC6A

Crystal structure of human ggt1 in complex with serine borate
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
342
structure length
342
Chain Sequence
DNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDAVLYMPSAPLSGPVLALILNILKGYNFSRESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISDDTTHPISYYKPEFYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Human gamma-Glutamyl Transpeptidase 1: STRUCTURES OF THE FREE ENZYME, INHIBITOR-BOUND TETRAHEDRAL TRANSITION STATES, AND GLUTAMATE-BOUND ENZYME REVEAL NOVEL MOVEMENT WITHIN THE ACTIVE SITE DURING CATALYSIS.
pubmed doi rcsb
molecule keywords Gamma-glutamyltranspeptidase 1 heavy chain
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
total genus 110
structure length 342
sequence length 342
ec nomenclature ec 2.3.2.2: Gamma-glutamyltransferase.
pdb deposition date 2015-04-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.130 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4zc6A02
2Z8JA 3A75A 3WHSA 4OTUA 2DBWA 2DBUA 2NQOA 2Z8IA 5BPKA 3FNMA 4GDXA 3WHRA 4GG2A 2DG5A 4ZBKA 2E0XA 4ZCGA 3WHQA 2Z8KA 5B5TA 2QMCA 2QM6A 2DBXA 2E0YA 4Z9OA 4OTTA 4ZC6A 2V36A
chains in the Genus database with same CATH superfamily
2XW1A 2BXPA 2BXBA 4PO0A 1HK2A 2DBWA 5GHKA 4G03A 5DQFA 1MA9A 1LOTA 5BPKA 2BXEA 3FNMA 5ID7A 5DBYA 1TXUA 1E7BA 4I9OA 4W4UB 4ZBKA 4ZBQA 1VZSA 4NAWB 5IIUA 2BXHA 4OT2A 2KWFA 2BXLA 4IW2A 3JQZA 2JUHA 4LB2A 4LUHA 4ZUXV 1IJGA 3GQUA 1LNSA 2QMCA 3GA9L 3LU6A 3B9MA 3B9LA 5GINA 3CX9A 2LQHA 2DBXA 2E0YA 4N0FD 1UORA 1MUHA 4OTTA 3FWBC 3LU7A 3LU8A 1E78A 1E7IA 4JK4A 2NQOA 4F5TA 2EFCA 5FUOA 4M70B 5D7GA 3WHRA 4WA6B 3KIKA 1MUSA 4TQ0A 3MHHB 2BXIA 1MIVA 2EFEA 4TQ1A 1HK5A 1KDXA 1TF0A 1HA2A 2LXSA 5IJEA 5IFOA 2DYOA 2LOQA 5ID9A 2OZBB 3BPJA 4S1YA 2OT3A 2BXKA 2QM6A 5GIPA 1VFIA 4Z69A 4L9KA 5IIHA 4OR0A 2QHBA 1E7EA 3PLAA 3A73A 2XSIA 4G01A 3V09A 2BXOA 1E7AA 3JRYA 2K0NA 4FJCB 3WHSA 5GIOA 2VDBA 2XVWA 3A75A 4LA0A 3FWCC 3H3AA 3TDLA 4EMXA 3H37A 1H5WA 1GNIA 2BXFA 2I30A 4K71A 2ROHA 3M99C 2BXDA 4N0UD 3SIUB 1H9ZA 3ICXA 5HOZA 2LQIA 2XMOA 3G9KD 4F5SA 1BJ5A 4GG2A 3GQXA 2XVVA 1O9XA 4MBEC 1JNBA 4L9QA 5IIXA 2DG5A 4GDLB 2E0XA 4J2VA 4DHXB 4F5VA 2GUTA 3NMUA 1N5UA 4ZCGA 3WHQA 1HK1A 4C31B 3VQIA 5B5TA 3V03A 1E7CA 3V08A 2LXTA 4IW1A 4ZBRA 4L8UA 4HGKA 3ECPA 1MM8A 4K2CA 5IJFA 1KW2A 4E99A 1BKEA 2EFDA 4G04A 2VUFA 3NVIA 4Z9OA 4ZC6A 5IJ5A 1E7HA 1NT2B 2Z8JA 2AGHB 1MIWA 2XVUA 1GNJA 4HGMB 3SQJA 4OTUA 1E7FA 1E7GA 2BXGA 2DBUA 1J78A 2BXNA 2AJEA 2Z8IA 3KJLA 3MHSB 4FK5B 4LUFA 1SB0A 2BXAA 2KBZA 4GDXA 1FOUA 2NNWA 4DM0A 1KXPD 4FIPB 3SIVB 4BY9C 1HK3A 2I2ZA 2XW0A 4LB9A 3UIVA 1J7EA 4BKEA 2EFHA 3NVMA 4D7XA 2YDFA 1AO6A 1BM0A 2DYMA 4N3ZA 2Z8KA 1HK4A 2CKXA 4F5UA 1MIYA 2XVQA 2BXCA 2BXQA 3W1SA 2BX8A 2BXMA 2VUEA 4GDKB 3NVKA 2V36A
chains in the Genus database with same CATH topology
2XW1A 2BXPA 2BXBA 4PO0A 1HK2A 2DBWA 5GHKA 4G03A 5DQFA 1MA9A 1LOTA 5BPKA 2BXEA 3FNMA 5ID7A 5DBYA 1TXUA 1E7BA 4W4UB 4ZBKA 4ZBQA 1VZSA 4NAWB 5IIUA 2BXHA 4OT2A 2BXLA 4IW2A 3JQZA 2JUHA 4LB2A 4LUHA 4ZUXV 1IJGA 3GQUA 1LNSA 2QMCA 3GA9L 3LU6A 3B9MA 3B9LA 5GINA 3CX9A 2DBXA 2E0YA 4N0FD 1UORA 4OTTA 3FWBC 3LU7A 3LU8A 1E78A 1E7IA 4JK4A 2NQOA 4F5TA 2EFCA 5FUOA 4M70B 5D7GA 3WHRA 4WA6B 3KIKA 4TQ0A 3MHHB 2BXIA 1MIVA 2EFEA 4TQ1A 1HK5A 1TF0A 1HA2A 5IJEA 5IFOA 2DYOA 2LOQA 5ID9A 2OZBB 4S1YA 2OT3A 2BXKA 2QM6A 5GIPA 1VFIA 4Z69A 4L9KA 5IIHA 4OR0A 2QHBA 1E7EA 3PLAA 3A73A 2XSIA 4G01A 3V09A 2BXOA 1E7AA 3JRYA 3WHSA 4FJCB 5GIOA 2VDBA 2XVWA 3A75A 4LA0A 3FWCC 3H3AA 3TDLA 4EMXA 3H37A 1H5WA 1GNIA 2BXFA 2I30A 4K71A 2ROHA 3M99C 2BXDA 4N0UD 3SIUB 1H9ZA 3ICXA 5HOZA 2XMOA 3G9KD 4F5SA 1BJ5A 4GG2A 3GQXA 2XVVA 1O9XA 4MBEC 1JNBA 4L9QA 5IIXA 2DG5A 4GDLB 2E0XA 4J2VA 4DHXB 4F5VA 3NMUA 1N5UA 4ZCGA 3WHQA 1HK1A 4C31B 3VQIA 5B5TA 3V03A 1E7CA 3V08A 4IW1A 4ZBRA 4L8UA 4HGKA 4K2CA 5IJFA 1KW2A 4E99A 1BKEA 2EFDA 4G04A 2VUFA 3NVIA 4Z9OA 4ZC6A 5IJ5A 1E7HA 1NT2B 2Z8JA 1MIWA 2XVUA 1GNJA 4HGMB 3SQJA 4OTUA 1E7FA 1E7GA 2BXGA 2DBUA 1J78A 2BXNA 2AJEA 2Z8IA 3KJLA 3MHSB 4FK5B 4LUFA 2BXAA 2KBZA 4GDXA 1FOUA 2NNWA 1KXPD 4FIPB 3SIVB 4BY9C 1HK3A 2I2ZA 2XW0A 4LB9A 3UIVA 1J7EA 4BKEA 2EFHA 3NVMA 1AO6A 2YDFA 1BM0A 2DYMA 4N3ZA 2Z8KA 1HK4A 2CKXA 4F5UA 1MIYA 2XVQA 2BXCA 2BXQA 3W1SA 2BX8A 2BXMA 2VUEA 4GDKB 3NVKA 2V36A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Z8J A;  3A75 A;  3WHS A;  4OTU A;  2DBW A;  2DBU A;  2NQO A;  2Z8I A;  5BPK A;  3FNM A;  4GDX A;  3WHR A;  4GG2 A;  2DG5 A;  4ZBK A;  2E0X A;  4ZCG A;  3WHQ A;  2Z8K A;  5B5T A;  2QMC A;  2QM6 A;  2DBX A;  2E0Y A;  4Z9O A;  4OTT A;  4ZC6 A;  2V36 A; 
#chains in the Genus database with same CATH topology
 2XW1 A;  2BXP A;  2BXB A;  4PO0 A;  1HK2 A;  2DBW A;  5GHK A;  4G03 A;  5DQF A;  1MA9 A;  1LOT A;  5BPK A;  2BXE A;  3FNM A;  5ID7 A;  5DBY A;  1TXU A;  1E7B A;  4I9O A;  4W4U B;  4ZBK A;  4ZBQ A;  1VZS A;  4NAW B;  5IIU A;  2BXH A;  4OT2 A;  2KWF A;  2BXL A;  4IW2 A;  3JQZ A;  2JUH A;  4LB2 A;  4LUH A;  4ZUX V;  1IJG A;  3GQU A;  1LNS A;  2QMC A;  3GA9 L;  3LU6 A;  3B9M A;  3B9L A;  5GIN A;  3CX9 A;  2LQH A;  2DBX A;  2E0Y A;  4N0F D;  1UOR A;  1MUH A;  4OTT A;  3FWB C;  3LU7 A;  3LU8 A;  1E78 A;  1E7I A;  4JK4 A;  2NQO A;  4F5T A;  2EFC A;  5FUO A;  4M70 B;  5D7G A;  3WHR A;  4WA6 B;  3KIK A;  1MUS A;  4TQ0 A;  3MHH B;  2BXI A;  1MIV A;  2EFE A;  4TQ1 A;  1HK5 A;  1KDX A;  1TF0 A;  1HA2 A;  2LXS A;  5IJE A;  5IFO A;  2DYO A;  2LOQ A;  5ID9 A;  2OZB B;  3BPJ A;  4S1Y A;  2OT3 A;  2BXK A;  2QM6 A;  5GIP A;  1VFI A;  4Z69 A;  4L9K A;  5IIH A;  4OR0 A;  2QHB A;  1E7E A;  3PLA A;  3A73 A;  2XSI A;  4G01 A;  3V09 A;  2BXO A;  1E7A A;  3JRY A;  2K0N A;  4FJC B;  3WHS A;  5GIO A;  2VDB A;  2XVW A;  3A75 A;  4LA0 A;  3FWC C;  3H3A A;  3TDL A;  4EMX A;  3H37 A;  1H5W A;  1GNI A;  2BXF A;  2I30 A;  4K71 A;  2ROH A;  3M99 C;  2BXD A;  4N0U D;  3SIU B;  1H9Z A;  3ICX A;  5HOZ A;  2LQI A;  2XMO A;  3G9K D;  4F5S A;  1BJ5 A;  4GG2 A;  3GQX A;  2XVV A;  1O9X A;  4MBE C;  1JNB A;  4L9Q A;  5IIX A;  2DG5 A;  4GDL B;  2E0X A;  4J2V A;  4DHX B;  4F5V A;  2GUT A;  3NMU A;  1N5U A;  4ZCG A;  3WHQ A;  1HK1 A;  4C31 B;  3VQI A;  5B5T A;  3V03 A;  1E7C A;  3V08 A;  2LXT A;  4IW1 A;  4ZBR A;  4L8U A;  4HGK A;  3ECP A;  1MM8 A;  4K2C A;  5IJF A;  1KW2 A;  4E99 A;  1BKE A;  2EFD A;  4G04 A;  2VUF A;  3NVI A;  4Z9O A;  4ZC6 A;  5IJ5 A;  1E7H A;  1NT2 B;  2Z8J A;  2AGH B;  1MIW A;  2XVU A;  1GNJ A;  4HGM B;  3SQJ A;  4OTU A;  1E7F A;  1E7G A;  2BXG A;  2DBU A;  1J78 A;  2BXN A;  2AJE A;  2Z8I A;  3KJL A;  3MHS B;  4FK5 B;  4LUF A;  1SB0 A;  2BXA A;  2KBZ A;  4GDX A;  1FOU A;  2NNW A;  4DM0 A;  1KXP D;  4FIP B;  3SIV B;  4BY9 C;  1HK3 A;  2I2Z A;  2XW0 A;  4LB9 A;  3UIV A;  1J7E A;  4BKE A;  2EFH A;  3NVM A;  4D7X A;  2YDF A;  1AO6 A;  1BM0 A;  2DYM A;  4N3Z A;  2Z8K A;  1HK4 A;  2CKX A;  4F5U A;  1MIY A;  2XVQ A;  2BXC A;  2BXQ A;  3W1S A;  2BX8 A;  2BXM A;  2VUE A;  4GDK B;  3NVK A;  2V36 A; 
#chains in the Genus database with same CATH homology
 2XW1 A;  2BXP A;  2BXB A;  4PO0 A;  1HK2 A;  2DBW A;  5GHK A;  4G03 A;  5DQF A;  1MA9 A;  1LOT A;  5BPK A;  2BXE A;  3FNM A;  5ID7 A;  5DBY A;  1TXU A;  1E7B A;  4W4U B;  4ZBK A;  4ZBQ A;  1VZS A;  4NAW B;  5IIU A;  2BXH A;  4OT2 A;  2BXL A;  4IW2 A;  3JQZ A;  2JUH A;  4LB2 A;  4LUH A;  4ZUX V;  1IJG A;  3GQU A;  1LNS A;  2QMC A;  3GA9 L;  3LU6 A;  3B9M A;  3B9L A;  5GIN A;  3CX9 A;  2DBX A;  2E0Y A;  4N0F D;  1UOR A;  4OTT A;  3FWB C;  3LU7 A;  3LU8 A;  1E78 A;  1E7I A;  4JK4 A;  2NQO A;  4F5T A;  2EFC A;  5FUO A;  4M70 B;  5D7G A;  3WHR A;  4WA6 B;  3KIK A;  4TQ0 A;  3MHH B;  2BXI A;  1MIV A;  2EFE A;  4TQ1 A;  1HK5 A;  1TF0 A;  1HA2 A;  5IJE A;  5IFO A;  2DYO A;  2LOQ A;  5ID9 A;  2OZB B;  4S1Y A;  2OT3 A;  2BXK A;  2QM6 A;  5GIP A;  1VFI A;  4Z69 A;  4L9K A;  5IIH A;  4OR0 A;  2QHB A;  1E7E A;  3PLA A;  3A73 A;  2XSI A;  4G01 A;  3V09 A;  2BXO A;  1E7A A;  3JRY A;  3WHS A;  4FJC B;  5GIO A;  2VDB A;  2XVW A;  3A75 A;  4LA0 A;  3FWC C;  3H3A A;  3TDL A;  4EMX A;  3H37 A;  1H5W A;  1GNI A;  2BXF A;  2I30 A;  4K71 A;  2ROH A;  3M99 C;  2BXD A;  4N0U D;  3SIU B;  1H9Z A;  3ICX A;  5HOZ A;  2XMO A;  3G9K D;  4F5S A;  1BJ5 A;  4GG2 A;  3GQX A;  2XVV A;  1O9X A;  4MBE C;  1JNB A;  4L9Q A;  5IIX A;  2DG5 A;  4GDL B;  2E0X A;  4J2V A;  4DHX B;  4F5V A;  3NMU A;  1N5U A;  4ZCG A;  3WHQ A;  1HK1 A;  4C31 B;  3VQI A;  5B5T A;  3V03 A;  1E7C A;  3V08 A;  4IW1 A;  4ZBR A;  4L8U A;  4HGK A;  4K2C A;  5IJF A;  1KW2 A;  4E99 A;  1BKE A;  2EFD A;  4G04 A;  2VUF A;  3NVI A;  4Z9O A;  4ZC6 A;  5IJ5 A;  1E7H A;  1NT2 B;  2Z8J A;  1MIW A;  2XVU A;  1GNJ A;  4HGM B;  3SQJ A;  4OTU A;  1E7F A;  1E7G A;  2BXG A;  2DBU A;  1J78 A;  2BXN A;  2AJE A;  2Z8I A;  3KJL A;  3MHS B;  4FK5 B;  4LUF A;  2BXA A;  2KBZ A;  4GDX A;  1FOU A;  2NNW A;  1KXP D;  4FIP B;  3SIV B;  4BY9 C;  1HK3 A;  2I2Z A;  2XW0 A;  4LB9 A;  3UIV A;  1J7E A;  4BKE A;  2EFH A;  3NVM A;  1AO6 A;  2YDF A;  1BM0 A;  2DYM A;  4N3Z A;  2Z8K A;  1HK4 A;  2CKX A;  4F5U A;  1MIY A;  2XVQ A;  2BXC A;  2BXQ A;  3W1S A;  2BX8 A;  2BXM A;  2VUE A;  4GDK B;  3NVK A;  2V36 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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