4ZG6A

Structural basis for inhibition of human autotaxin by four novel compounds
Total Genus 245
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
245
Knots found
sequence length
804
structure length
754
Chain Sequence
GSCKGRCFELCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIAALTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGTEERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Ectonucleotide pyrophosphatase/phosphodiesterase family memb
publication title Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase/hydrolase inhibitor
total genus 245
structure length 754
sequence length 804
chains with identical sequence B
other databases KnotProt 2.0: S -31
ec nomenclature ec 3.1.4.39: Alkylglycerophosphoethanolamine phosphodiesterase.
pdb deposition date 2015-04-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01033 Somatomedin_B Somatomedin B domain
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
A PF01663 Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 4zg6A04
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4zg6A03
2W5SA 1KH7A 2GSOA 3OWVA 3BDHA 5GKPA 3OT9A 3M8YA 2IFYA 2RH6A 1Y6VA 3M7VA 5GRRA 1SMNA 2W5QA 4FDJA 2GLQA 3UNYA 1ANIA 5EGEA 3ISMA 1FSUA 4CYSA 4UPHA 5K4PA 4GTZA 4FDIA 3BDGB 2IUCA 1KHLA 2ANHA 2XGRA 5LRMA 4GTWA 3MK1A 4CYRA 3IDDA 1E3CP 4KJGA 1URAA 4YR1A 1N2LA 4ZGAA 3TX0A 2W5XA 1HDHA 3MK0A 1QL0A 4N7TA 3SZYA 5C66A 3DYCA 1ALJA 1HJKA 1ED9A 1AJAA 4LREA 1ZEDA 1KHJA 1ALHA 5KXAA 1Y7AA 4LRCA 3NKMA 1ELZA 3B5QA 3IGYB 4UOOA 2W5RA 5IJSA 1KHKA 2ZKTA 1EW2A 1ZEBA 4NWXA 2IUCB 4QAXA 1B8JA 3Q3QA 3KD8A 4LR7A 4LR9A 4MIVA 5GOVA 3WAYA 5L0EA 1AUKA 3LXQA 5DLTA 1KH4A 3M8ZA 3TG0A 2W8SA 4LRAA 3T01A 4ZG9A 1K7HA 4QN0A 1ALIA 3NKOA 5LIAA 1KH9A 5LRNA 4ZG7A 3DPCA 1EJJA 4UORA 4KAVA 4NWJA 2W5TA 4KM4A 4LRFA 1KH5A 2W8DA 3TWZA 4UPIA 1SHNA 4GTXA 1E33P 5L0BA 4LRDA 3UN2A 3IGZB 4KJDA 1URBA 3S5BA 1AJBA 4TN0A 2VQRA 1KHNA 3T00A 4LRBA 3NVLA 1AJCA 1G8TA 3WAXA 5EGHA 4UPLA 4MY4A 4UOPA 3E2DA 1ANJA 2D1GA 2QZUA 1ED8A 5INHA 4B56A 5L0KA 1ELYA 1EI6A 2X98A 1QAEA 4LQYA 3NKPA 4E3YA 5IJQA 3WAVA 3T02A 3CMRA 2GSNA 1EQJA 4KAYA 3UO0A 4CXKA 2GSUA 1SHQA 2W5VA 3UN3A 1HQAA 3NKRA 1O98A 3ED4A 4ZG6A 1AJDA 1ALKA 3A52A 4QH0A 1E2SP 2GA3A 4CXSA 3WAWA 1O99A 3NKQA 4CXUA 5DLWA 1ZM8A 4UPKA 3M8WA 5AJ9A 5TJ3A 1E1ZP 4LR2A 1P49A 5DLVA 2W5WA 2XRGA 4LR8A 3BDFA 1N2KA 4QGOA 1ZEFA 5HRTA 3BDGA 3MK2A 2XH3A 4MHXA 1EW8A 1EW9A 3UN5A 1ELXA 3NKNA 2XR9A 3SZZA 4GTYA 2G9YA 3WBHA 4A1NA 5GKCA 2O3BA 5LQQA
chains in the Genus database with same CATH superfamily
2W5SA 1KH7A 2GSOA 3OWVA 3BDHA 5GKPA 3OT9A 3M8YA 2IFYA 2RH6A 1Y6VA 3M7VA 5GRRA 1SMNA 2W5QA 4FDJA 2GLQA 3UNYA 1ANIA 5EGEA 3ISMA 1FSUA 4CYSA 4UPHA 5K4PA 4GTZA 4FDIA 3BDGB 2IUCA 1KHLA 2ANHA 2XGRA 5LRMA 4GTWA 3MK1A 4CYRA 3IDDA 1E3CP 4KJGA 1URAA 4YR1A 1N2LA 4ZGAA 3TX0A 2W5XA 1HDHA 3MK0A 1QL0A 4N7TA 3SZYA 5C66A 3DYCA 1ALJA 1HJKA 1ED9A 1AJAA 4LREA 1ZEDA 1KHJA 1ALHA 5KXAA 1Y7AA 4LRCA 3NKMA 1ELZA 3B5QA 3IGYB 4UOOA 2W5RA 5IJSA 1KHKA 2ZKTA 1EW2A 1ZEBA 4NWXA 2IUCB 4QAXA 1B8JA 3Q3QA 3KD8A 4LR7A 4LR9A 4MIVA 5GOVA 3WAYA 5L0EA 1AUKA 3LXQA 5DLTA 1KH4A 3M8ZA 3TG0A 2W8SA 4LRAA 3T01A 4ZG9A 1K7HA 4QN0A 1ALIA 3NKOA 5LIAA 1KH9A 5LRNA 4ZG7A 3DPCA 1EJJA 4UORA 4KAVA 4NWJA 2W5TA 4KM4A 4LRFA 1KH5A 2W8DA 3TWZA 4UPIA 1SHNA 4GTXA 1E33P 5L0BA 4LRDA 3UN2A 3IGZB 4KJDA 1URBA 3S5BA 1AJBA 4TN0A 2VQRA 1KHNA 3T00A 4LRBA 3NVLA 1AJCA 1G8TA 3WAXA 5EGHA 4UPLA 4MY4A 4UOPA 3E2DA 1ANJA 2D1GA 2QZUA 1ED8A 5INHA 4B56A 5L0KA 1ELYA 1EI6A 2X98A 1QAEA 4LQYA 3NKPA 4E3YA 5IJQA 3WAVA 3T02A 3CMRA 2GSNA 1EQJA 4KAYA 3UO0A 4CXKA 2GSUA 1SHQA 2W5VA 3UN3A 1HQAA 3NKRA 1O98A 3ED4A 4ZG6A 1AJDA 1ALKA 3A52A 4QH0A 1E2SP 2GA3A 4CXSA 3WAWA 1O99A 3NKQA 4CXUA 5DLWA 1ZM8A 4UPKA 3M8WA 5AJ9A 5TJ3A 1E1ZP 4LR2A 1P49A 5DLVA 2W5WA 2XRGA 4LR8A 3BDFA 1N2KA 4QGOA 1ZEFA 5HRTA 3BDGA 3MK2A 2XH3A 4MHXA 1EW8A 1EW9A 3UN5A 1ELXA 3NKNA 2XR9A 3SZZA 4GTYA 2G9YA 3WBHA 4A1NA 5GKCA 2O3BA 5LQQA
chains in the Genus database with same CATH topology
2W5SA 1KH7A 2GSOA 3OWVA 3BDHA 5GKPA 3OT9A 3M8YA 2IFYA 2RH6A 1Y6VA 3M7VA 5GRRA 1SMNA 2W5QA 4FDJA 2GLQA 3UNYA 1ANIA 5EGEA 3ISMA 1FSUA 4CYSA 4UPHA 5K4PA 4GTZA 4FDIA 3BDGB 2IUCA 1KHLA 2ANHA 2XGRA 5LRMA 4GTWA 3MK1A 4CYRA 3IDDA 1E3CP 4KJGA 1URAA 4YR1A 1N2LA 4ZGAA 3TX0A 2W5XA 1HDHA 3MK0A 1QL0A 4N7TA 3SZYA 5C66A 3DYCA 1ALJA 1HJKA 1ED9A 1AJAA 4LREA 1ZEDA 1KHJA 1ALHA 5KXAA 1Y7AA 4LRCA 3NKMA 1ELZA 3B5QA 3IGYB 4UOOA 2W5RA 5IJSA 1KHKA 2ZKTA 1EW2A 1ZEBA 4NWXA 2IUCB 4QAXA 1B8JA 3Q3QA 3KD8A 4LR7A 4LR9A 4MIVA 5GOVA 3WAYA 5L0EA 1AUKA 3LXQA 5DLTA 1KH4A 3M8ZA 3TG0A 2W8SA 4LRAA 3T01A 4ZG9A 1K7HA 4QN0A 1ALIA 3NKOA 5LIAA 1KH9A 5LRNA 4ZG7A 3DPCA 1EJJA 4UORA 4KAVA 4NWJA 2W5TA 4KM4A 4LRFA 1KH5A 2W8DA 3TWZA 4UPIA 1SHNA 4GTXA 1E33P 5L0BA 4LRDA 3UN2A 3IGZB 4KJDA 1URBA 3S5BA 1AJBA 4TN0A 2VQRA 1KHNA 3T00A 4LRBA 3NVLA 1AJCA 1G8TA 3WAXA 5EGHA 4UPLA 4MY4A 4UOPA 3E2DA 1ANJA 2D1GA 2QZUA 1ED8A 5INHA 4B56A 5L0KA 1ELYA 1EI6A 2X98A 1QAEA 4LQYA 3NKPA 4E3YA 5IJQA 3WAVA 3T02A 3CMRA 2GSNA 1EQJA 4KAYA 3UO0A 4CXKA 2GSUA 1SHQA 2W5VA 3UN3A 1HQAA 3NKRA 1O98A 3ED4A 4ZG6A 1AJDA 1ALKA 3A52A 4QH0A 1E2SP 2GA3A 4CXSA 3WAWA 1O99A 3NKQA 4CXUA 5DLWA 1ZM8A 4UPKA 3M8WA 5AJ9A 5TJ3A 1E1ZP 4LR2A 1P49A 5DLVA 2W5WA 2XRGA 4LR8A 3BDFA 1N2KA 4QGOA 1ZEFA 5HRTA 3BDGA 3MK2A 2XH3A 4MHXA 1EW8A 1EW9A 3UN5A 1ELXA 3NKNA 2XR9A 3SZZA 4GTYA 2G9YA 3WBHA 4A1NA 5GKCA 2O3BA 5LQQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W5S A;  1KH7 A;  2GSO A;  3OWV A;  3BDH A;  5GKP A;  3OT9 A;  3M8Y A;  2IFY A;  2RH6 A;  1Y6V A;  3M7V A;  5GRR A;  1SMN A;  2W5Q A;  4FDJ A;  2GLQ A;  3UNY A;  1ANI A;  5EGE A;  3ISM A;  1FSU A;  4CYS A;  4UPH A;  5K4P A;  4GTZ A;  4FDI A;  3BDG B;  2IUC A;  1KHL A;  2ANH A;  2XGR A;  5LRM A;  4GTW A;  3MK1 A;  4CYR A;  3IDD A;  1E3C P;  4KJG A;  1URA A;  4YR1 A;  1N2L A;  4ZGA A;  3TX0 A;  2W5X A;  1HDH A;  3MK0 A;  1QL0 A;  4N7T A;  3SZY A;  5C66 A;  3DYC A;  1ALJ A;  1HJK A;  1ED9 A;  1AJA A;  4LRE A;  1ZED A;  1KHJ A;  1ALH A;  5KXA A;  1Y7A A;  4LRC A;  3NKM A;  1ELZ A;  3B5Q A;  3IGY B;  4UOO A;  2W5R A;  5IJS A;  1KHK A;  2ZKT A;  1EW2 A;  1ZEB A;  4NWX A;  2IUC B;  4QAX A;  1B8J A;  3Q3Q A;  3KD8 A;  4LR7 A;  4LR9 A;  4MIV A;  5GOV A;  3WAY A;  5L0E A;  1AUK A;  3LXQ A;  5DLT A;  1KH4 A;  3M8Z A;  3TG0 A;  2W8S A;  4LRA A;  3T01 A;  4ZG9 A;  1K7H A;  4QN0 A;  1ALI A;  3NKO A;  5LIA A;  1KH9 A;  5LRN A;  4ZG7 A;  3DPC A;  1EJJ A;  4UOR A;  4KAV A;  4NWJ A;  2W5T A;  4KM4 A;  4LRF A;  1KH5 A;  2W8D A;  3TWZ A;  4UPI A;  1SHN A;  4GTX A;  1E33 P;  5L0B A;  4LRD A;  3UN2 A;  3IGZ B;  4KJD A;  1URB A;  3S5B A;  1AJB A;  4TN0 A;  2VQR A;  1KHN A;  3T00 A;  4LRB A;  3NVL A;  1AJC A;  1G8T A;  3WAX A;  5EGH A;  4UPL A;  4MY4 A;  4UOP A;  3E2D A;  1ANJ A;  2D1G A;  2QZU A;  1ED8 A;  5INH A;  4B56 A;  5L0K A;  1ELY A;  1EI6 A;  2X98 A;  1QAE A;  4LQY A;  3NKP A;  4E3Y A;  5IJQ A;  3WAV A;  3T02 A;  3CMR A;  2GSN A;  1EQJ A;  4KAY A;  3UO0 A;  4CXK A;  2GSU A;  1SHQ A;  2W5V A;  3UN3 A;  1HQA A;  3NKR A;  1O98 A;  3ED4 A;  4ZG6 A;  1AJD A;  1ALK A;  3A52 A;  4QH0 A;  1E2S P;  2GA3 A;  4CXS A;  3WAW A;  1O99 A;  3NKQ A;  4CXU A;  5DLW A;  1ZM8 A;  4UPK A;  3M8W A;  5AJ9 A;  5TJ3 A;  1E1Z P;  4LR2 A;  1P49 A;  5DLV A;  2W5W A;  2XRG A;  4LR8 A;  3BDF A;  1N2K A;  4QGO A;  1ZEF A;  5HRT A;  3BDG A;  3MK2 A;  2XH3 A;  4MHX A;  1EW8 A;  1EW9 A;  3UN5 A;  1ELX A;  3NKN A;  2XR9 A;  3SZZ A;  4GTY A;  2G9Y A;  3WBH A;  4A1N A;  5GKC A;  2O3B A;  5LQQ A; 
#chains in the Genus database with same CATH topology
 2W5S A;  1KH7 A;  2GSO A;  3OWV A;  3BDH A;  5GKP A;  3OT9 A;  3M8Y A;  2IFY A;  2RH6 A;  1Y6V A;  3M7V A;  5GRR A;  1SMN A;  2W5Q A;  4FDJ A;  2GLQ A;  3UNY A;  1ANI A;  5EGE A;  3ISM A;  1FSU A;  4CYS A;  4UPH A;  5K4P A;  4GTZ A;  4FDI A;  3BDG B;  2IUC A;  1KHL A;  2ANH A;  2XGR A;  5LRM A;  4GTW A;  3MK1 A;  4CYR A;  3IDD A;  1E3C P;  4KJG A;  1URA A;  4YR1 A;  1N2L A;  4ZGA A;  3TX0 A;  2W5X A;  1HDH A;  3MK0 A;  1QL0 A;  4N7T A;  3SZY A;  5C66 A;  3DYC A;  1ALJ A;  1HJK A;  1ED9 A;  1AJA A;  4LRE A;  1ZED A;  1KHJ A;  1ALH A;  5KXA A;  1Y7A A;  4LRC A;  3NKM A;  1ELZ A;  3B5Q A;  3IGY B;  4UOO A;  2W5R A;  5IJS A;  1KHK A;  2ZKT A;  1EW2 A;  1ZEB A;  4NWX A;  2IUC B;  4QAX A;  1B8J A;  3Q3Q A;  3KD8 A;  4LR7 A;  4LR9 A;  4MIV A;  5GOV A;  3WAY A;  5L0E A;  1AUK A;  3LXQ A;  5DLT A;  1KH4 A;  3M8Z A;  3TG0 A;  2W8S A;  4LRA A;  3T01 A;  4ZG9 A;  1K7H A;  4QN0 A;  1ALI A;  3NKO A;  5LIA A;  1KH9 A;  5LRN A;  4ZG7 A;  3DPC A;  1EJJ A;  4UOR A;  4KAV A;  4NWJ A;  2W5T A;  4KM4 A;  4LRF A;  1KH5 A;  2W8D A;  3TWZ A;  4UPI A;  1SHN A;  4GTX A;  1E33 P;  5L0B A;  4LRD A;  3UN2 A;  3IGZ B;  4KJD A;  1URB A;  3S5B A;  1AJB A;  4TN0 A;  2VQR A;  1KHN A;  3T00 A;  4LRB A;  3NVL A;  1AJC A;  1G8T A;  3WAX A;  5EGH A;  4UPL A;  4MY4 A;  4UOP A;  3E2D A;  1ANJ A;  2D1G A;  2QZU A;  1ED8 A;  5INH A;  4B56 A;  5L0K A;  1ELY A;  1EI6 A;  2X98 A;  1QAE A;  4LQY A;  3NKP A;  4E3Y A;  5IJQ A;  3WAV A;  3T02 A;  3CMR A;  2GSN A;  1EQJ A;  4KAY A;  3UO0 A;  4CXK A;  2GSU A;  1SHQ A;  2W5V A;  3UN3 A;  1HQA A;  3NKR A;  1O98 A;  3ED4 A;  4ZG6 A;  1AJD A;  1ALK A;  3A52 A;  4QH0 A;  1E2S P;  2GA3 A;  4CXS A;  3WAW A;  1O99 A;  3NKQ A;  4CXU A;  5DLW A;  1ZM8 A;  4UPK A;  3M8W A;  5AJ9 A;  5TJ3 A;  1E1Z P;  4LR2 A;  1P49 A;  5DLV A;  2W5W A;  2XRG A;  4LR8 A;  3BDF A;  1N2K A;  4QGO A;  1ZEF A;  5HRT A;  3BDG A;  3MK2 A;  2XH3 A;  4MHX A;  1EW8 A;  1EW9 A;  3UN5 A;  1ELX A;  3NKN A;  2XR9 A;  3SZZ A;  4GTY A;  2G9Y A;  3WBH A;  4A1N A;  5GKC A;  2O3B A;  5LQQ A; 
#chains in the Genus database with same CATH homology
 2W5S A;  1KH7 A;  2GSO A;  3OWV A;  3BDH A;  5GKP A;  3OT9 A;  3M8Y A;  2IFY A;  2RH6 A;  1Y6V A;  3M7V A;  5GRR A;  1SMN A;  2W5Q A;  4FDJ A;  2GLQ A;  3UNY A;  1ANI A;  5EGE A;  3ISM A;  1FSU A;  4CYS A;  4UPH A;  5K4P A;  4GTZ A;  4FDI A;  3BDG B;  2IUC A;  1KHL A;  2ANH A;  2XGR A;  5LRM A;  4GTW A;  3MK1 A;  4CYR A;  3IDD A;  1E3C P;  4KJG A;  1URA A;  4YR1 A;  1N2L A;  4ZGA A;  3TX0 A;  2W5X A;  1HDH A;  3MK0 A;  1QL0 A;  4N7T A;  3SZY A;  5C66 A;  3DYC A;  1ALJ A;  1HJK A;  1ED9 A;  1AJA A;  4LRE A;  1ZED A;  1KHJ A;  1ALH A;  5KXA A;  1Y7A A;  4LRC A;  3NKM A;  1ELZ A;  3B5Q A;  3IGY B;  4UOO A;  2W5R A;  5IJS A;  1KHK A;  2ZKT A;  1EW2 A;  1ZEB A;  4NWX A;  2IUC B;  4QAX A;  1B8J A;  3Q3Q A;  3KD8 A;  4LR7 A;  4LR9 A;  4MIV A;  5GOV A;  3WAY A;  5L0E A;  1AUK A;  3LXQ A;  5DLT A;  1KH4 A;  3M8Z A;  3TG0 A;  2W8S A;  4LRA A;  3T01 A;  4ZG9 A;  1K7H A;  4QN0 A;  1ALI A;  3NKO A;  5LIA A;  1KH9 A;  5LRN A;  4ZG7 A;  3DPC A;  1EJJ A;  4UOR A;  4KAV A;  4NWJ A;  2W5T A;  4KM4 A;  4LRF A;  1KH5 A;  2W8D A;  3TWZ A;  4UPI A;  1SHN A;  4GTX A;  1E33 P;  5L0B A;  4LRD A;  3UN2 A;  3IGZ B;  4KJD A;  1URB A;  3S5B A;  1AJB A;  4TN0 A;  2VQR A;  1KHN A;  3T00 A;  4LRB A;  3NVL A;  1AJC A;  1G8T A;  3WAX A;  5EGH A;  4UPL A;  4MY4 A;  4UOP A;  3E2D A;  1ANJ A;  2D1G A;  2QZU A;  1ED8 A;  5INH A;  4B56 A;  5L0K A;  1ELY A;  1EI6 A;  2X98 A;  1QAE A;  4LQY A;  3NKP A;  4E3Y A;  5IJQ A;  3WAV A;  3T02 A;  3CMR A;  2GSN A;  1EQJ A;  4KAY A;  3UO0 A;  4CXK A;  2GSU A;  1SHQ A;  2W5V A;  3UN3 A;  1HQA A;  3NKR A;  1O98 A;  3ED4 A;  4ZG6 A;  1AJD A;  1ALK A;  3A52 A;  4QH0 A;  1E2S P;  2GA3 A;  4CXS A;  3WAW A;  1O99 A;  3NKQ A;  4CXU A;  5DLW A;  1ZM8 A;  4UPK A;  3M8W A;  5AJ9 A;  5TJ3 A;  1E1Z P;  4LR2 A;  1P49 A;  5DLV A;  2W5W A;  2XRG A;  4LR8 A;  3BDF A;  1N2K A;  4QGO A;  1ZEF A;  5HRT A;  3BDG A;  3MK2 A;  2XH3 A;  4MHX A;  1EW8 A;  1EW9 A;  3UN5 A;  1ELX A;  3NKN A;  2XR9 A;  3SZZ A;  4GTY A;  2G9Y A;  3WBH A;  4A1N A;  5GKC A;  2O3B A;  5LQQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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