4ZJTA

X-ray crystal structure of lymnaea stagnalis acetylcholine binding protein (lsachbp) in complex with 2-thiophenylmethylene anabaseine (2tab)
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
215
structure length
212
Chain Sequence
DDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPNSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRSEIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray crystal structure of Lymnaea stagnalis acetylcholine binding protein (LsAChBP) in complex with 2-Thiophenylmethylene Anabaseine (2TAB)
rcsb
molecule tags Acetylcholine binding protein
source organism Lymnaea stagnalis
molecule keywords Acetylcholine-binding protein
total genus 49
structure length 212
sequence length 215
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date 2015-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 4zjtA00
2C9TA 3WTHA 3SIOA 3ZDHA 5L4EA 4AFGA 4XHEA 4ZR6A 4QH1A 2YOEA 5J5IA 2YMEA 2YKSA 2BG9E 3TLTA 4HFIA 2XZ6A 2ZJVA 2WN9A 2WZYA 5HEUA 5AFNA 3U8NA 2W8GA 5KZUA 5CO5A 5HEJA 2XYTA 4IL9A 1UX2A 2XQ9A 2XQ4A 4ZJTA 4HFEA 4FRRA 2ZJUA 2Y54A 4ILBA 3EI0A 4WV9A 3WTLA 3P50A 4ZK1A 3IGQA 4UY2A 5AFJA 4HFBA 4HQPA 4IREA 2YN6A 5J5FA 3T4MA 3UU6A 4HFDA 3PEOA 4LMLA 2BR7A 2X00D 3WTIA 2XNUA 4D01A 3UQ7A 4Z91A 4TNWA 2Y56A 4PIRA 5J0ZA 4QH4A 5AFHA 5J5HA 3U8LA 5CFBA 4F8HA 3EAMA 4QH5A 3EHZA 4LMJA 5LG3A 4LMKA 5KE4A 2VL0A 4TWDA 5HCMA 3RI5A 3WTOA 2XQ7A 2Y7YA 2BG9A 3U8JA 4QACA 3U8MA 3UQ4A 4UXUA 2WNLA 4ZRUA 3TLVA 3JADA 3RIFA 4A98A 2WNCA 3WTMA 4AFTA 3ZKRA 2XQ8A 3UU5A 5HEHA 5HEOA 3TLUA 4A97A 3RQWA 4QABA 4TWHA 2BYRA 1UW6A 4X5TA 3RIAA 4NZBA 2Y58A 3TLSA 3UU8A 2BG9B 3WTKA 2PH9A 4B5DA 1UV6A 2PGZA 5FJVA 5BW2A 4BFQA 2XQ5A 5L4HA 3TLWA 3WIPA 2BYPA 3ZDGA 2Y57A 5HEGA 4COFA 3WTNA 4ZZBA 5AFMA 4EZ1A 3U8KA 4DBMA 2BYQA 5J5GA 4Z90A 3C79A 3JAEA 3C84A 3LSVA 4AFHA 4UM3S 5LXBA 2XQ3A 4TNVA 5IUXA 4HFCA 4ZK4A 5AFKA 2W8FA 4ILCA 3P4WA 2BR8A 2X00A 3GUAA 4TWFA 4UM1A 5SYOA 2XQ6A 5JMEA 3JAFA 3SQ6A 2BYNA 3RQUA 4UM3A 5HCJA 5AFMB 2WNJA 5BP0A 4XK9A 4ZZCA 3UUBA 3RHWA 5AINA 4HFHA 5BRXA 2BG9C 4UM3P 1I9BA 2QC1B 5AFLA 2XQAA 4QAAA 4IL4A 3UU4A 2BYSA 5TVCA 4ZJSA 2UZ6A 2BJ0A 3PMZA 3UU3A 4NPPA 3SH1A 4ALXA 4ILAA 5L47A 2XYSA 2XNTA 2YMDA 3WTJA 4BQTA 2XZ5A 2XNVA 3SQ9A
chains in the Genus database with same CATH superfamily
2C9TA 3WTHA 3SIOA 3ZDHA 5L4EA 4AFGA 4XHEA 4ZR6A 4QH1A 2YOEA 5J5IA 2YMEA 2YKSA 2BG9E 3TLTA 4HFIA 2XZ6A 2ZJVA 2WN9A 2WZYA 5HEUA 5AFNA 3U8NA 2W8GA 5KZUA 5CO5A 5HEJA 2XYTA 4IL9A 1UX2A 2XQ9A 2XQ4A 4ZJTA 4HFEA 4FRRA 2ZJUA 2Y54A 4ILBA 3EI0A 4WV9A 3WTLA 3P50A 4ZK1A 3IGQA 4UY2A 5AFJA 4HFBA 4HQPA 4IREA 2YN6A 5J5FA 3T4MA 3UU6A 4HFDA 3PEOA 4LMLA 2BR7A 2X00D 3WTIA 2XNUA 4D01A 3UQ7A 4Z91A 4TNWA 2Y56A 4PIRA 5J0ZA 4QH4A 5AFHA 5J5HA 3U8LA 5CFBA 4F8HA 3EAMA 4QH5A 3EHZA 4LMJA 5LG3A 4LMKA 5KE4A 2VL0A 4TWDA 5HCMA 3RI5A 3WTOA 2XQ7A 2Y7YA 2BG9A 3U8JA 4QACA 3U8MA 3UQ4A 4UXUA 2WNLA 4ZRUA 3TLVA 3JADA 3RIFA 4A98A 2WNCA 3WTMA 4AFTA 3ZKRA 2XQ8A 3UU5A 5HEHA 5HEOA 3TLUA 4A97A 3RQWA 4QABA 4TWHA 2BYRA 1UW6A 4X5TA 3RIAA 4NZBA 2Y58A 3TLSA 3UU8A 2BG9B 3WTKA 2PH9A 4B5DA 1UV6A 2PGZA 5FJVA 5BW2A 4BFQA 2XQ5A 5L4HA 3TLWA 3WIPA 2BYPA 3ZDGA 2Y57A 5HEGA 4COFA 3WTNA 4ZZBA 5AFMA 4EZ1A 3U8KA 4DBMA 2BYQA 5J5GA 4Z90A 3C79A 3JAEA 3C84A 3LSVA 4AFHA 4UM3S 5LXBA 2XQ3A 4TNVA 5IUXA 4HFCA 4ZK4A 5AFKA 2W8FA 4ILCA 3P4WA 2BR8A 2X00A 3GUAA 4TWFA 4UM1A 5SYOA 2XQ6A 5JMEA 3JAFA 3SQ6A 2BYNA 3RQUA 4UM3A 5HCJA 5AFMB 2WNJA 5BP0A 4XK9A 4ZZCA 3UUBA 3RHWA 5AINA 4HFHA 5BRXA 2BG9C 4UM3P 1I9BA 2QC1B 5AFLA 2XQAA 4QAAA 4IL4A 3UU4A 2BYSA 5TVCA 4ZJSA 2UZ6A 2BJ0A 3PMZA 3UU3A 4NPPA 3SH1A 4ALXA 4ILAA 5L47A 2XYSA 2XNTA 2YMDA 3WTJA 4BQTA 2XZ5A 2XNVA 3SQ9A
chains in the Genus database with same CATH topology
2C9TA 3WTHA 3SIOA 3ZDHA 5L4EA 4AFGA 4XHEA 4ZR6A 4QH1A 2YOEA 5J5IA 2YMEA 2YKSA 2BG9E 3TLTA 4HFIA 2XZ6A 2ZJVA 2WN9A 2WZYA 5HEUA 5AFNA 3U8NA 2W8GA 5KZUA 5CO5A 5HEJA 2XYTA 4IL9A 1UX2A 2XQ9A 2XQ4A 4ZJTA 4HFEA 4FRRA 2ZJUA 2Y54A 4ILBA 3EI0A 4WV9A 3WTLA 3P50A 4ZK1A 3IGQA 4UY2A 5AFJA 4HFBA 4HQPA 4IREA 2YN6A 5J5FA 3T4MA 3UU6A 4HFDA 3PEOA 4LMLA 2BR7A 2X00D 3WTIA 2XNUA 4D01A 3UQ7A 4Z91A 4TNWA 2Y56A 4PIRA 5J0ZA 4QH4A 5AFHA 5J5HA 3U8LA 5CFBA 4F8HA 3EAMA 4QH5A 3EHZA 4LMJA 5LG3A 4LMKA 5KE4A 2VL0A 4TWDA 5HCMA 3RI5A 3WTOA 2XQ7A 2Y7YA 2BG9A 3U8JA 4QACA 3U8MA 3UQ4A 4UXUA 2WNLA 4ZRUA 3TLVA 3JADA 3RIFA 4A98A 2WNCA 3WTMA 4AFTA 3ZKRA 2XQ8A 3UU5A 5HEHA 5HEOA 3TLUA 4A97A 3RQWA 4QABA 4TWHA 2BYRA 1UW6A 4X5TA 3RIAA 4NZBA 2Y58A 3TLSA 3UU8A 2BG9B 3WTKA 2PH9A 4B5DA 1UV6A 2PGZA 5FJVA 5BW2A 4BFQA 2XQ5A 5L4HA 3TLWA 3WIPA 2BYPA 3ZDGA 2Y57A 5HEGA 4COFA 3WTNA 4ZZBA 5AFMA 4EZ1A 3U8KA 4DBMA 2BYQA 5J5GA 4Z90A 3C79A 3JAEA 3C84A 3LSVA 4AFHA 4UM3S 5LXBA 2XQ3A 4TNVA 5IUXA 4HFCA 4ZK4A 5AFKA 2W8FA 4ILCA 3P4WA 2BR8A 2X00A 3GUAA 4TWFA 4UM1A 5SYOA 2XQ6A 5JMEA 3JAFA 3SQ6A 2BYNA 3RQUA 4UM3A 5HCJA 5AFMB 2WNJA 5BP0A 4XK9A 4ZZCA 3UUBA 3RHWA 5AINA 4HFHA 5BRXA 2BG9C 4UM3P 1I9BA 2QC1B 5AFLA 2XQAA 4QAAA 4IL4A 3UU4A 2BYSA 5TVCA 4ZJSA 2UZ6A 2BJ0A 3PMZA 3UU3A 4NPPA 3SH1A 4ALXA 4ILAA 5L47A 2XYSA 2XNTA 2YMDA 3WTJA 4BQTA 2XZ5A 2XNVA 3SQ9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2C9T A;  3WTH A;  3SIO A;  3ZDH A;  5L4E A;  4AFG A;  4XHE A;  4ZR6 A;  4QH1 A;  2YOE A;  5J5I A;  2YME A;  2YKS A;  2BG9 E;  3TLT A;  4HFI A;  2XZ6 A;  2ZJV A;  2WN9 A;  2WZY A;  5HEU A;  5AFN A;  3U8N A;  2W8G A;  5KZU A;  5CO5 A;  5HEJ A;  2XYT A;  4IL9 A;  1UX2 A;  2XQ9 A;  2XQ4 A;  4ZJT A;  4HFE A;  4FRR A;  2ZJU A;  2Y54 A;  4ILB A;  3EI0 A;  4WV9 A;  3WTL A;  3P50 A;  4ZK1 A;  3IGQ A;  4UY2 A;  5AFJ A;  4HFB A;  4HQP A;  4IRE A;  2YN6 A;  5J5F A;  3T4M A;  3UU6 A;  4HFD A;  3PEO A;  4LML A;  2BR7 A;  2X00 D;  3WTI A;  2XNU A;  4D01 A;  3UQ7 A;  4Z91 A;  4TNW A;  2Y56 A;  4PIR A;  5J0Z A;  4QH4 A;  5AFH A;  5J5H A;  3U8L A;  5CFB A;  4F8H A;  3EAM A;  4QH5 A;  3EHZ A;  4LMJ A;  5LG3 A;  4LMK A;  5KE4 A;  2VL0 A;  4TWD A;  5HCM A;  3RI5 A;  3WTO A;  2XQ7 A;  2Y7Y A;  2BG9 A;  3U8J A;  4QAC A;  3U8M A;  3UQ4 A;  4UXU A;  2WNL A;  4ZRU A;  3TLV A;  3JAD A;  3RIF A;  4A98 A;  2WNC A;  3WTM A;  4AFT A;  3ZKR A;  2XQ8 A;  3UU5 A;  5HEH A;  5HEO A;  3TLU A;  4A97 A;  3RQW A;  4QAB A;  4TWH A;  2BYR A;  1UW6 A;  4X5T A;  3RIA A;  4NZB A;  2Y58 A;  3TLS A;  3UU8 A;  2BG9 B;  3WTK A;  2PH9 A;  4B5D A;  1UV6 A;  2PGZ A;  5FJV A;  5BW2 A;  4BFQ A;  2XQ5 A;  5L4H A;  3TLW A;  3WIP A;  2BYP A;  3ZDG A;  2Y57 A;  5HEG A;  4COF A;  3WTN A;  4ZZB A;  5AFM A;  4EZ1 A;  3U8K A;  4DBM A;  2BYQ A;  5J5G A;  4Z90 A;  3C79 A;  3JAE A;  3C84 A;  3LSV A;  4AFH A;  4UM3 S;  5LXB A;  2XQ3 A;  4TNV A;  5IUX A;  4HFC A;  4ZK4 A;  5AFK A;  2W8F A;  4ILC A;  3P4W A;  2BR8 A;  2X00 A;  3GUA A;  4TWF A;  4UM1 A;  5SYO A;  2XQ6 A;  5JME A;  3JAF A;  3SQ6 A;  2BYN A;  3RQU A;  4UM3 A;  5HCJ A;  5AFM B;  2WNJ A;  5BP0 A;  4XK9 A;  4ZZC A;  3UUB A;  3RHW A;  5AIN A;  4HFH A;  5BRX A;  2BG9 C;  4UM3 P;  1I9B A;  2QC1 B;  5AFL A;  2XQA A;  4QAA A;  4IL4 A;  3UU4 A;  2BYS A;  5TVC A;  4ZJS A;  2UZ6 A;  2BJ0 A;  3PMZ A;  3UU3 A;  4NPP A;  3SH1 A;  4ALX A;  4ILA A;  5L47 A;  2XYS A;  2XNT A;  2YMD A;  3WTJ A;  4BQT A;  2XZ5 A;  2XNV A;  3SQ9 A; 
#chains in the Genus database with same CATH topology
 2C9T A;  3WTH A;  3SIO A;  3ZDH A;  5L4E A;  4AFG A;  4XHE A;  4ZR6 A;  4QH1 A;  2YOE A;  5J5I A;  2YME A;  2YKS A;  2BG9 E;  3TLT A;  4HFI A;  2XZ6 A;  2ZJV A;  2WN9 A;  2WZY A;  5HEU A;  5AFN A;  3U8N A;  2W8G A;  5KZU A;  5CO5 A;  5HEJ A;  2XYT A;  4IL9 A;  1UX2 A;  2XQ9 A;  2XQ4 A;  4ZJT A;  4HFE A;  4FRR A;  2ZJU A;  2Y54 A;  4ILB A;  3EI0 A;  4WV9 A;  3WTL A;  3P50 A;  4ZK1 A;  3IGQ A;  4UY2 A;  5AFJ A;  4HFB A;  4HQP A;  4IRE A;  2YN6 A;  5J5F A;  3T4M A;  3UU6 A;  4HFD A;  3PEO A;  4LML A;  2BR7 A;  2X00 D;  3WTI A;  2XNU A;  4D01 A;  3UQ7 A;  4Z91 A;  4TNW A;  2Y56 A;  4PIR A;  5J0Z A;  4QH4 A;  5AFH A;  5J5H A;  3U8L A;  5CFB A;  4F8H A;  3EAM A;  4QH5 A;  3EHZ A;  4LMJ A;  5LG3 A;  4LMK A;  5KE4 A;  2VL0 A;  4TWD A;  5HCM A;  3RI5 A;  3WTO A;  2XQ7 A;  2Y7Y A;  2BG9 A;  3U8J A;  4QAC A;  3U8M A;  3UQ4 A;  4UXU A;  2WNL A;  4ZRU A;  3TLV A;  3JAD A;  3RIF A;  4A98 A;  2WNC A;  3WTM A;  4AFT A;  3ZKR A;  2XQ8 A;  3UU5 A;  5HEH A;  5HEO A;  3TLU A;  4A97 A;  3RQW A;  4QAB A;  4TWH A;  2BYR A;  1UW6 A;  4X5T A;  3RIA A;  4NZB A;  2Y58 A;  3TLS A;  3UU8 A;  2BG9 B;  3WTK A;  2PH9 A;  4B5D A;  1UV6 A;  2PGZ A;  5FJV A;  5BW2 A;  4BFQ A;  2XQ5 A;  5L4H A;  3TLW A;  3WIP A;  2BYP A;  3ZDG A;  2Y57 A;  5HEG A;  4COF A;  3WTN A;  4ZZB A;  5AFM A;  4EZ1 A;  3U8K A;  4DBM A;  2BYQ A;  5J5G A;  4Z90 A;  3C79 A;  3JAE A;  3C84 A;  3LSV A;  4AFH A;  4UM3 S;  5LXB A;  2XQ3 A;  4TNV A;  5IUX A;  4HFC A;  4ZK4 A;  5AFK A;  2W8F A;  4ILC A;  3P4W A;  2BR8 A;  2X00 A;  3GUA A;  4TWF A;  4UM1 A;  5SYO A;  2XQ6 A;  5JME A;  3JAF A;  3SQ6 A;  2BYN A;  3RQU A;  4UM3 A;  5HCJ A;  5AFM B;  2WNJ A;  5BP0 A;  4XK9 A;  4ZZC A;  3UUB A;  3RHW A;  5AIN A;  4HFH A;  5BRX A;  2BG9 C;  4UM3 P;  1I9B A;  2QC1 B;  5AFL A;  2XQA A;  4QAA A;  4IL4 A;  3UU4 A;  2BYS A;  5TVC A;  4ZJS A;  2UZ6 A;  2BJ0 A;  3PMZ A;  3UU3 A;  4NPP A;  3SH1 A;  4ALX A;  4ILA A;  5L47 A;  2XYS A;  2XNT A;  2YMD A;  3WTJ A;  4BQT A;  2XZ5 A;  2XNV A;  3SQ9 A; 
#chains in the Genus database with same CATH homology
 2C9T A;  3WTH A;  3SIO A;  3ZDH A;  5L4E A;  4AFG A;  4XHE A;  4ZR6 A;  4QH1 A;  2YOE A;  5J5I A;  2YME A;  2YKS A;  2BG9 E;  3TLT A;  4HFI A;  2XZ6 A;  2ZJV A;  2WN9 A;  2WZY A;  5HEU A;  5AFN A;  3U8N A;  2W8G A;  5KZU A;  5CO5 A;  5HEJ A;  2XYT A;  4IL9 A;  1UX2 A;  2XQ9 A;  2XQ4 A;  4ZJT A;  4HFE A;  4FRR A;  2ZJU A;  2Y54 A;  4ILB A;  3EI0 A;  4WV9 A;  3WTL A;  3P50 A;  4ZK1 A;  3IGQ A;  4UY2 A;  5AFJ A;  4HFB A;  4HQP A;  4IRE A;  2YN6 A;  5J5F A;  3T4M A;  3UU6 A;  4HFD A;  3PEO A;  4LML A;  2BR7 A;  2X00 D;  3WTI A;  2XNU A;  4D01 A;  3UQ7 A;  4Z91 A;  4TNW A;  2Y56 A;  4PIR A;  5J0Z A;  4QH4 A;  5AFH A;  5J5H A;  3U8L A;  5CFB A;  4F8H A;  3EAM A;  4QH5 A;  3EHZ A;  4LMJ A;  5LG3 A;  4LMK A;  5KE4 A;  2VL0 A;  4TWD A;  5HCM A;  3RI5 A;  3WTO A;  2XQ7 A;  2Y7Y A;  2BG9 A;  3U8J A;  4QAC A;  3U8M A;  3UQ4 A;  4UXU A;  2WNL A;  4ZRU A;  3TLV A;  3JAD A;  3RIF A;  4A98 A;  2WNC A;  3WTM A;  4AFT A;  3ZKR A;  2XQ8 A;  3UU5 A;  5HEH A;  5HEO A;  3TLU A;  4A97 A;  3RQW A;  4QAB A;  4TWH A;  2BYR A;  1UW6 A;  4X5T A;  3RIA A;  4NZB A;  2Y58 A;  3TLS A;  3UU8 A;  2BG9 B;  3WTK A;  2PH9 A;  4B5D A;  1UV6 A;  2PGZ A;  5FJV A;  5BW2 A;  4BFQ A;  2XQ5 A;  5L4H A;  3TLW A;  3WIP A;  2BYP A;  3ZDG A;  2Y57 A;  5HEG A;  4COF A;  3WTN A;  4ZZB A;  5AFM A;  4EZ1 A;  3U8K A;  4DBM A;  2BYQ A;  5J5G A;  4Z90 A;  3C79 A;  3JAE A;  3C84 A;  3LSV A;  4AFH A;  4UM3 S;  5LXB A;  2XQ3 A;  4TNV A;  5IUX A;  4HFC A;  4ZK4 A;  5AFK A;  2W8F A;  4ILC A;  3P4W A;  2BR8 A;  2X00 A;  3GUA A;  4TWF A;  4UM1 A;  5SYO A;  2XQ6 A;  5JME A;  3JAF A;  3SQ6 A;  2BYN A;  3RQU A;  4UM3 A;  5HCJ A;  5AFM B;  2WNJ A;  5BP0 A;  4XK9 A;  4ZZC A;  3UUB A;  3RHW A;  5AIN A;  4HFH A;  5BRX A;  2BG9 C;  4UM3 P;  1I9B A;  2QC1 B;  5AFL A;  2XQA A;  4QAA A;  4IL4 A;  3UU4 A;  2BYS A;  5TVC A;  4ZJS A;  2UZ6 A;  2BJ0 A;  3PMZ A;  3UU3 A;  4NPP A;  3SH1 A;  4ALX A;  4ILA A;  5L47 A;  2XYS A;  2XNT A;  2YMD A;  3WTJ A;  4BQT A;  2XZ5 A;  2XNV A;  3SQ9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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