4ZR6A

Lymnaea stagnalis acetylcholine binding protein in complex with 3-[(4e)-4-[(3-methylimidazol-4-yl)methylene]-2,3-dihydropyrrol-5-yl]pyridine
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
203
structure length
195
Chain Sequence
DRADILYNIRQTSRPDVIPTRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-guided design and analysis of arylidene anabaseines and myosmines
rcsb
molecule keywords Acetylcholine-binding protein
molecule tags Acetylcholine binding protein
source organism Lymnaea stagnalis
total genus 37
structure length 195
sequence length 203
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2015-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 4zr6A00
4ALXA 3IGQA 3UU6A 2W8FA 4LMJA 2C9TA 3JAEA 5LG3A 5J5GA 3SIOA 2YKSA 2PGZA 2YOEA 5KE4A 2XNVA 2WZYA 3C84A 4ZRUA 3UUBA 2XYTA 4XK9A 2Y54A 4AFGA 4NPPA 3UU4A 4HFIA 3WTNA 1UV6A 2XNTA 2XQ9A 4PIRA 3TLTA 4COFA 3WTLA 4ILCA 4LMLA 1UW6A 2XQ4A 3TLVA 3RQUA 4IL9A 4XHEA 5AFMA 2ZJVA 5FJVA 2XQ7A 2XZ6A 2X00A 4Z90A 5HCJA 2BG9C 3RIFA 4DBMA 4EZ1A 5AFJA 5KZUA 3ZDGA 3U8KA 4BFQA 3JADA 2Y58A 5L4HA 3U8NA 2BYRA 5AFKA 4HFBA 4ZJSA 4A98A 3EI0A 4AFHA 3LSVA 2XQ3A 2XQ6A 2WNLA 3TLWA 3U8JA 5L47A 2Y57A 2Y56A 4Z91A 4QH5A 4ILBA 5L4EA 5J0ZA 4QH4A 4TWFA 5BW2A 3U8MA 4HFHA 5HEOA 4HFDA 2XZ5A 4HFEA 2XQAA 3PEOA 3WTIA 4NZBA 4UM3A 5HEGA 5JMEA 2BR7A 2VL0A 5HEHA 3T4MA 2YN6A 4UXUA 2QC1B 4LMKA 4QH1A 2BYSA 3EHZA 5J5HA 2Y7YA 2YMDA 4IL4A 2W8GA 5HCMA 4F8HA 2BG9E 1I9BA 4ZJTA 5BP0A 2XQ8A 2XYSA 3SQ9A 3TLSA 5AFMB 3ZKRA 2X00D 4X5TA 4ZZCA 5CO5A 4UM3P 3TLUA 2XNUA 2PH9A 2ZJUA 4HQPA 4UM3S 5AFLA 3PMZA 5IUXA 4A97A 3EAMA 4ILAA 5BRXA 4HFCA 3U8LA 3UQ7A 2BG9A 3RHWA 5HEJA 3P4WA 3ZDHA 3WIPA 2BYQA 4FRRA 5TVCA 3P50A 4ZK4A 4QAAA 4AFTA 3RQWA 3UQ4A 4IREA 2WN9A 5AFHA 5J5FA 2WNJA 5CFBA 2BJ0A 4WV9A 3WTHA 5SYOA 5HEUA 4TWDA 2BR8A 5AFNA 4TWHA 2XQ5A 4ZR6A 3UU5A 5J5IA 5LXBA 3C79A 2WNCA 3GUAA 3WTMA 2UZ6A 2BYNA 3SQ6A 4TNWA 1UX2A 3RI5A 3UU3A 3WTJA 2YMEA 4D01A 3UU8A 4B5DA 4UY2A 3WTOA 4UM1A 3SH1A 4QABA 5AINA 4ZZBA 3JAFA 4ZK1A 3RIAA 4TNVA 2BG9B 4BQTA 4QACA 3WTKA 2BYPA
chains in the Genus database with same CATH superfamily
4ALXA 3IGQA 3UU6A 2W8FA 4LMJA 2C9TA 3JAEA 5LG3A 5J5GA 3SIOA 2YKSA 2PGZA 2YOEA 5KE4A 2XNVA 2WZYA 3C84A 4ZRUA 3UUBA 2XYTA 4XK9A 2Y54A 4AFGA 4NPPA 3UU4A 4HFIA 3WTNA 1UV6A 2XNTA 2XQ9A 4PIRA 3TLTA 4COFA 3WTLA 4ILCA 4LMLA 1UW6A 2XQ4A 3TLVA 3RQUA 4IL9A 4XHEA 5AFMA 2ZJVA 5FJVA 2XQ7A 2XZ6A 2X00A 4Z90A 5HCJA 2BG9C 3RIFA 4DBMA 4EZ1A 5AFJA 5KZUA 3ZDGA 3U8KA 4BFQA 3JADA 2Y58A 5L4HA 3U8NA 2BYRA 5AFKA 4HFBA 4ZJSA 4A98A 3EI0A 4AFHA 3LSVA 2XQ3A 2XQ6A 2WNLA 3TLWA 3U8JA 5L47A 2Y57A 2Y56A 4Z91A 4QH5A 4ILBA 5L4EA 5J0ZA 4QH4A 4TWFA 5BW2A 3U8MA 4HFHA 5HEOA 4HFDA 2XZ5A 4HFEA 2XQAA 3PEOA 3WTIA 4NZBA 4UM3A 5HEGA 5JMEA 2BR7A 2VL0A 5HEHA 3T4MA 2YN6A 4UXUA 2QC1B 4LMKA 4QH1A 2BYSA 3EHZA 5J5HA 2Y7YA 2YMDA 4IL4A 2W8GA 5HCMA 4F8HA 2BG9E 1I9BA 4ZJTA 5BP0A 2XQ8A 2XYSA 3SQ9A 3TLSA 5AFMB 3ZKRA 2X00D 4X5TA 4ZZCA 5CO5A 4UM3P 3TLUA 2XNUA 2PH9A 2ZJUA 4HQPA 4UM3S 5AFLA 3PMZA 5IUXA 4A97A 3EAMA 4ILAA 5BRXA 4HFCA 3U8LA 3UQ7A 2BG9A 3RHWA 5HEJA 3P4WA 3ZDHA 3WIPA 2BYQA 4FRRA 5TVCA 3P50A 4ZK4A 4QAAA 4AFTA 3RQWA 3UQ4A 4IREA 2WN9A 5AFHA 5J5FA 2WNJA 5CFBA 2BJ0A 4WV9A 3WTHA 5SYOA 5HEUA 4TWDA 2BR8A 5AFNA 4TWHA 2XQ5A 4ZR6A 3UU5A 5J5IA 5LXBA 3C79A 2WNCA 3GUAA 3WTMA 2UZ6A 2BYNA 3SQ6A 4TNWA 1UX2A 3RI5A 3UU3A 3WTJA 2YMEA 4D01A 3UU8A 4B5DA 4UY2A 3WTOA 4UM1A 3SH1A 4QABA 5AINA 4ZZBA 3JAFA 4ZK1A 3RIAA 4TNVA 2BG9B 4BQTA 4QACA 3WTKA 2BYPA
chains in the Genus database with same CATH topology
4ALXA 3IGQA 3UU6A 2W8FA 4LMJA 2C9TA 3JAEA 5LG3A 5J5GA 3SIOA 2YKSA 2PGZA 2YOEA 5KE4A 2XNVA 2WZYA 3C84A 4ZRUA 3UUBA 2XYTA 4XK9A 2Y54A 4AFGA 4NPPA 3UU4A 4HFIA 3WTNA 1UV6A 2XNTA 2XQ9A 4PIRA 3TLTA 4COFA 3WTLA 4ILCA 4LMLA 1UW6A 2XQ4A 3TLVA 3RQUA 4IL9A 4XHEA 5AFMA 2ZJVA 5FJVA 2XQ7A 2XZ6A 2X00A 4Z90A 5HCJA 2BG9C 3RIFA 4DBMA 4EZ1A 5AFJA 5KZUA 3ZDGA 3U8KA 4BFQA 3JADA 2Y58A 5L4HA 3U8NA 2BYRA 5AFKA 4HFBA 4ZJSA 4A98A 3EI0A 4AFHA 3LSVA 2XQ3A 2XQ6A 2WNLA 3TLWA 3U8JA 5L47A 2Y57A 2Y56A 4Z91A 4QH5A 4ILBA 5L4EA 5J0ZA 4QH4A 4TWFA 5BW2A 3U8MA 4HFHA 5HEOA 4HFDA 2XZ5A 4HFEA 2XQAA 3PEOA 3WTIA 4NZBA 4UM3A 5HEGA 5JMEA 2BR7A 2VL0A 5HEHA 3T4MA 2YN6A 4UXUA 2QC1B 4LMKA 4QH1A 2BYSA 3EHZA 5J5HA 2Y7YA 2YMDA 4IL4A 2W8GA 5HCMA 4F8HA 2BG9E 1I9BA 4ZJTA 5BP0A 2XQ8A 2XYSA 3SQ9A 3TLSA 5AFMB 3ZKRA 2X00D 4X5TA 4ZZCA 5CO5A 4UM3P 3TLUA 2XNUA 2PH9A 2ZJUA 4HQPA 4UM3S 5AFLA 3PMZA 5IUXA 4A97A 3EAMA 4ILAA 5BRXA 4HFCA 3U8LA 3UQ7A 2BG9A 3RHWA 5HEJA 3P4WA 3ZDHA 3WIPA 2BYQA 4FRRA 5TVCA 3P50A 4ZK4A 4QAAA 4AFTA 3RQWA 3UQ4A 4IREA 2WN9A 5AFHA 5J5FA 2WNJA 5CFBA 2BJ0A 4WV9A 3WTHA 5SYOA 5HEUA 4TWDA 2BR8A 5AFNA 4TWHA 2XQ5A 4ZR6A 3UU5A 5J5IA 5LXBA 3C79A 2WNCA 3GUAA 3WTMA 2UZ6A 2BYNA 3SQ6A 4TNWA 1UX2A 3RI5A 3UU3A 3WTJA 2YMEA 4D01A 3UU8A 4B5DA 4UY2A 3WTOA 4UM1A 3SH1A 4QABA 5AINA 4ZZBA 3JAFA 4ZK1A 3RIAA 4TNVA 2BG9B 4BQTA 4QACA 3WTKA 2BYPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ALX A;  3IGQ A;  3UU6 A;  2W8F A;  4LMJ A;  2C9T A;  3JAE A;  5LG3 A;  5J5G A;  3SIO A;  2YKS A;  2PGZ A;  2YOE A;  5KE4 A;  2XNV A;  2WZY A;  3C84 A;  4ZRU A;  3UUB A;  2XYT A;  4XK9 A;  2Y54 A;  4AFG A;  4NPP A;  3UU4 A;  4HFI A;  3WTN A;  1UV6 A;  2XNT A;  2XQ9 A;  4PIR A;  3TLT A;  4COF A;  3WTL A;  4ILC A;  4LML A;  1UW6 A;  2XQ4 A;  3TLV A;  3RQU A;  4IL9 A;  4XHE A;  5AFM A;  2ZJV A;  5FJV A;  2XQ7 A;  2XZ6 A;  2X00 A;  4Z90 A;  5HCJ A;  2BG9 C;  3RIF A;  4DBM A;  4EZ1 A;  5AFJ A;  5KZU A;  3ZDG A;  3U8K A;  4BFQ A;  3JAD A;  2Y58 A;  5L4H A;  3U8N A;  2BYR A;  5AFK A;  4HFB A;  4ZJS A;  4A98 A;  3EI0 A;  4AFH A;  3LSV A;  2XQ3 A;  2XQ6 A;  2WNL A;  3TLW A;  3U8J A;  5L47 A;  2Y57 A;  2Y56 A;  4Z91 A;  4QH5 A;  4ILB A;  5L4E A;  5J0Z A;  4QH4 A;  4TWF A;  5BW2 A;  3U8M A;  4HFH A;  5HEO A;  4HFD A;  2XZ5 A;  4HFE A;  2XQA A;  3PEO A;  3WTI A;  4NZB A;  4UM3 A;  5HEG A;  5JME A;  2BR7 A;  2VL0 A;  5HEH A;  3T4M A;  2YN6 A;  4UXU A;  2QC1 B;  4LMK A;  4QH1 A;  2BYS A;  3EHZ A;  5J5H A;  2Y7Y A;  2YMD A;  4IL4 A;  2W8G A;  5HCM A;  4F8H A;  2BG9 E;  1I9B A;  4ZJT A;  5BP0 A;  2XQ8 A;  2XYS A;  3SQ9 A;  3TLS A;  5AFM B;  3ZKR A;  2X00 D;  4X5T A;  4ZZC A;  5CO5 A;  4UM3 P;  3TLU A;  2XNU A;  2PH9 A;  2ZJU A;  4HQP A;  4UM3 S;  5AFL A;  3PMZ A;  5IUX A;  4A97 A;  3EAM A;  4ILA A;  5BRX A;  4HFC A;  3U8L A;  3UQ7 A;  2BG9 A;  3RHW A;  5HEJ A;  3P4W A;  3ZDH A;  3WIP A;  2BYQ A;  4FRR A;  5TVC A;  3P50 A;  4ZK4 A;  4QAA A;  4AFT A;  3RQW A;  3UQ4 A;  4IRE A;  2WN9 A;  5AFH A;  5J5F A;  2WNJ A;  5CFB A;  2BJ0 A;  4WV9 A;  3WTH A;  5SYO A;  5HEU A;  4TWD A;  2BR8 A;  5AFN A;  4TWH A;  2XQ5 A;  4ZR6 A;  3UU5 A;  5J5I A;  5LXB A;  3C79 A;  2WNC A;  3GUA A;  3WTM A;  2UZ6 A;  2BYN A;  3SQ6 A;  4TNW A;  1UX2 A;  3RI5 A;  3UU3 A;  3WTJ A;  2YME A;  4D01 A;  3UU8 A;  4B5D A;  4UY2 A;  3WTO A;  4UM1 A;  3SH1 A;  4QAB A;  5AIN A;  4ZZB A;  3JAF A;  4ZK1 A;  3RIA A;  4TNV A;  2BG9 B;  4BQT A;  4QAC A;  3WTK A;  2BYP A; 
#chains in the Genus database with same CATH topology
 4ALX A;  3IGQ A;  3UU6 A;  2W8F A;  4LMJ A;  2C9T A;  3JAE A;  5LG3 A;  5J5G A;  3SIO A;  2YKS A;  2PGZ A;  2YOE A;  5KE4 A;  2XNV A;  2WZY A;  3C84 A;  4ZRU A;  3UUB A;  2XYT A;  4XK9 A;  2Y54 A;  4AFG A;  4NPP A;  3UU4 A;  4HFI A;  3WTN A;  1UV6 A;  2XNT A;  2XQ9 A;  4PIR A;  3TLT A;  4COF A;  3WTL A;  4ILC A;  4LML A;  1UW6 A;  2XQ4 A;  3TLV A;  3RQU A;  4IL9 A;  4XHE A;  5AFM A;  2ZJV A;  5FJV A;  2XQ7 A;  2XZ6 A;  2X00 A;  4Z90 A;  5HCJ A;  2BG9 C;  3RIF A;  4DBM A;  4EZ1 A;  5AFJ A;  5KZU A;  3ZDG A;  3U8K A;  4BFQ A;  3JAD A;  2Y58 A;  5L4H A;  3U8N A;  2BYR A;  5AFK A;  4HFB A;  4ZJS A;  4A98 A;  3EI0 A;  4AFH A;  3LSV A;  2XQ3 A;  2XQ6 A;  2WNL A;  3TLW A;  3U8J A;  5L47 A;  2Y57 A;  2Y56 A;  4Z91 A;  4QH5 A;  4ILB A;  5L4E A;  5J0Z A;  4QH4 A;  4TWF A;  5BW2 A;  3U8M A;  4HFH A;  5HEO A;  4HFD A;  2XZ5 A;  4HFE A;  2XQA A;  3PEO A;  3WTI A;  4NZB A;  4UM3 A;  5HEG A;  5JME A;  2BR7 A;  2VL0 A;  5HEH A;  3T4M A;  2YN6 A;  4UXU A;  2QC1 B;  4LMK A;  4QH1 A;  2BYS A;  3EHZ A;  5J5H A;  2Y7Y A;  2YMD A;  4IL4 A;  2W8G A;  5HCM A;  4F8H A;  2BG9 E;  1I9B A;  4ZJT A;  5BP0 A;  2XQ8 A;  2XYS A;  3SQ9 A;  3TLS A;  5AFM B;  3ZKR A;  2X00 D;  4X5T A;  4ZZC A;  5CO5 A;  4UM3 P;  3TLU A;  2XNU A;  2PH9 A;  2ZJU A;  4HQP A;  4UM3 S;  5AFL A;  3PMZ A;  5IUX A;  4A97 A;  3EAM A;  4ILA A;  5BRX A;  4HFC A;  3U8L A;  3UQ7 A;  2BG9 A;  3RHW A;  5HEJ A;  3P4W A;  3ZDH A;  3WIP A;  2BYQ A;  4FRR A;  5TVC A;  3P50 A;  4ZK4 A;  4QAA A;  4AFT A;  3RQW A;  3UQ4 A;  4IRE A;  2WN9 A;  5AFH A;  5J5F A;  2WNJ A;  5CFB A;  2BJ0 A;  4WV9 A;  3WTH A;  5SYO A;  5HEU A;  4TWD A;  2BR8 A;  5AFN A;  4TWH A;  2XQ5 A;  4ZR6 A;  3UU5 A;  5J5I A;  5LXB A;  3C79 A;  2WNC A;  3GUA A;  3WTM A;  2UZ6 A;  2BYN A;  3SQ6 A;  4TNW A;  1UX2 A;  3RI5 A;  3UU3 A;  3WTJ A;  2YME A;  4D01 A;  3UU8 A;  4B5D A;  4UY2 A;  3WTO A;  4UM1 A;  3SH1 A;  4QAB A;  5AIN A;  4ZZB A;  3JAF A;  4ZK1 A;  3RIA A;  4TNV A;  2BG9 B;  4BQT A;  4QAC A;  3WTK A;  2BYP A; 
#chains in the Genus database with same CATH homology
 4ALX A;  3IGQ A;  3UU6 A;  2W8F A;  4LMJ A;  2C9T A;  3JAE A;  5LG3 A;  5J5G A;  3SIO A;  2YKS A;  2PGZ A;  2YOE A;  5KE4 A;  2XNV A;  2WZY A;  3C84 A;  4ZRU A;  3UUB A;  2XYT A;  4XK9 A;  2Y54 A;  4AFG A;  4NPP A;  3UU4 A;  4HFI A;  3WTN A;  1UV6 A;  2XNT A;  2XQ9 A;  4PIR A;  3TLT A;  4COF A;  3WTL A;  4ILC A;  4LML A;  1UW6 A;  2XQ4 A;  3TLV A;  3RQU A;  4IL9 A;  4XHE A;  5AFM A;  2ZJV A;  5FJV A;  2XQ7 A;  2XZ6 A;  2X00 A;  4Z90 A;  5HCJ A;  2BG9 C;  3RIF A;  4DBM A;  4EZ1 A;  5AFJ A;  5KZU A;  3ZDG A;  3U8K A;  4BFQ A;  3JAD A;  2Y58 A;  5L4H A;  3U8N A;  2BYR A;  5AFK A;  4HFB A;  4ZJS A;  4A98 A;  3EI0 A;  4AFH A;  3LSV A;  2XQ3 A;  2XQ6 A;  2WNL A;  3TLW A;  3U8J A;  5L47 A;  2Y57 A;  2Y56 A;  4Z91 A;  4QH5 A;  4ILB A;  5L4E A;  5J0Z A;  4QH4 A;  4TWF A;  5BW2 A;  3U8M A;  4HFH A;  5HEO A;  4HFD A;  2XZ5 A;  4HFE A;  2XQA A;  3PEO A;  3WTI A;  4NZB A;  4UM3 A;  5HEG A;  5JME A;  2BR7 A;  2VL0 A;  5HEH A;  3T4M A;  2YN6 A;  4UXU A;  2QC1 B;  4LMK A;  4QH1 A;  2BYS A;  3EHZ A;  5J5H A;  2Y7Y A;  2YMD A;  4IL4 A;  2W8G A;  5HCM A;  4F8H A;  2BG9 E;  1I9B A;  4ZJT A;  5BP0 A;  2XQ8 A;  2XYS A;  3SQ9 A;  3TLS A;  5AFM B;  3ZKR A;  2X00 D;  4X5T A;  4ZZC A;  5CO5 A;  4UM3 P;  3TLU A;  2XNU A;  2PH9 A;  2ZJU A;  4HQP A;  4UM3 S;  5AFL A;  3PMZ A;  5IUX A;  4A97 A;  3EAM A;  4ILA A;  5BRX A;  4HFC A;  3U8L A;  3UQ7 A;  2BG9 A;  3RHW A;  5HEJ A;  3P4W A;  3ZDH A;  3WIP A;  2BYQ A;  4FRR A;  5TVC A;  3P50 A;  4ZK4 A;  4QAA A;  4AFT A;  3RQW A;  3UQ4 A;  4IRE A;  2WN9 A;  5AFH A;  5J5F A;  2WNJ A;  5CFB A;  2BJ0 A;  4WV9 A;  3WTH A;  5SYO A;  5HEU A;  4TWD A;  2BR8 A;  5AFN A;  4TWH A;  2XQ5 A;  4ZR6 A;  3UU5 A;  5J5I A;  5LXB A;  3C79 A;  2WNC A;  3GUA A;  3WTM A;  2UZ6 A;  2BYN A;  3SQ6 A;  4TNW A;  1UX2 A;  3RI5 A;  3UU3 A;  3WTJ A;  2YME A;  4D01 A;  3UU8 A;  4B5D A;  4UY2 A;  3WTO A;  4UM1 A;  3SH1 A;  4QAB A;  5AIN A;  4ZZB A;  3JAF A;  4ZK1 A;  3RIA A;  4TNV A;  2BG9 B;  4BQT A;  4QAC A;  3WTK A;  2BYP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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