4BNEA

Pacsin2 interacts with membranes and actin-filaments
Total Genus 127
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
290
structure length
290
Chain Sequence
SDSFWEVGNYKRTVKRIDDGHRLCNDLMNCIHERARIEKVYAQQLTEWAKRWKQLVEKGPQYGTVERAWCAFMSEAEKVSELHLEVKGSLMNEDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAYHAACKEEKLAISRETNSKADPALNPEQLKKLQDKVERSKQDVLKTKAKYEKSLKELDNATPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVASYKNIYRELEQNIKTADAVEDLRWFRANQGPGMSMNWPQFEDD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Direct Interaction of Actin Filaments with F-Bar Protein Pacsin2.
pubmed doi rcsb
source organism Gallus gallus
molecule tags Endocytosis
molecule keywords PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROT
total genus 127
structure length 290
sequence length 290
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00018 SH3_1 SH3 domain
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 4bneA01
2RAKA 3HAHA 2V0OA 1X04A 4I1QA 2EFLA 3OK8A 3CAZA 2Z0NA 1X03A 1ZWWA 1WDZA 1URUA 4WPEA 3PLTA 3Q84A 3I2WA 1I4DA 3LLLA 5C5BB 2D4CA 2ELBA 4BNEA 3HAJA 3M3WA 2Q13A 2RAIA 4DCNC 2Q12A 2X3WA 3QE6A 4NQIA 4AVMA 2X3VA 3QNIA 2YKTA 1I4TA 1I4LA 2FICA 2Z0OA 4H8SA 2X3XA 4FZSA 4WPCA 3G9GA 4DYLA 2RAJA 4NSWA 3ACOA 3DYTA 2Z0VA 4ATMA 3QWEA 5C5BA 3Q0KA 3SOGA 3HAIA 3SYVA 2D1LA 2EFKA 2C08A 1I49A 3ABHA 1Y2OA 4AKVA
chains in the Genus database with same CATH superfamily
2KHOA 1OAOA 1W9MA 2RT6A 3CZSA 3CZNA 4I1QA 3I01A 4HYBA 2EFLA 3QNJA 4HR1A 3RPMA 4NPHA 3CAZA 4EZXA 2PY6A 3DPOA 1URUA 1E2UA 4JWCA 1I4DA 3DPQA 1MJGA 1GNLA 4JWDA 1TQTA 2OBLA 2QKWA 3DPPA 4JWEA 3OWGA 3BUQA 3T48A 3BVXA 1HXKA 1ZYLA 1TQWA 1E1DA 2Q12A 2X3WA 4AVMA 2GAFD 2LM0A 1DKZA 4JN4A 3KAWA 4KIKA 2YI8A 4F01A 3BUBA 2OBMA 2WYHA 2QXLA 3DYTA 3DX4A 5FIGA 3A98A 4F00A 3Q0KA 3L3PA 4EZSA 2D1LA 2EFKA 3D4YA 3GI7A 4E3CA 1Y2OA 2YL8A 2Z0OA 1O7DC 3CV5A 3D4ZA 1OA1A 4JNEA 3T46A 2RAKA 4AZCA 4EZUA 3D51A 3VKHA 4UDYX 3T47A 3KAVA 4H6HA 1R34A 2YI9A 2YIAA 4IW0A 4AZBA 1U00A 1ZWWA 3EJRA 2YL9A 4WPEA 1SU7A 1DKYA 3EJUA 2ZXQA 4EZTA 2WINM 3B53X 3OHXM 1R5EA 3EJSA 4JWIA 4IWQA 4EZNA 1SU8A 2D4CA 2GF4A 2F7PA 2F7OA 4EZZA 4BNEA 3L3OM 2LXYA 2OO2A 4IM3A 2OW6A 3CKDA 3ER8C 2Q13A 4DCNC 2OZNB 4AZIA 1TQUA 1YWMA 3DX0A 3BUPA 2X5CA 4KIKB 4NQIA 1SUFA 4AZHA 2X3VA 1I4LA 2F7QA 3BVTA 1E9VA 2X3XA 4R5KA 4WPCA 4AZ6A 3G9GA 4DYLA 1JQKA 3FD9A 3RV0A 3ACOA 2Z0VA 1SU6A 1TQSA 2GA9D 3BUIA 1HTYA 3DX3A 2F1BA 3SYVA 4R5JA 2F1AA 3DX2A 4EZRA 4AZGA 4FM3A 2OW7A 3EJTA 4R5LA 3BVUA 4UDXX 3RV1A 1X04A 3OK8A 4IWOA 3UITA 4EZYA 4EZQA 2YIBA 2YLAA 3BVWA 3B51X 3PLTA 3I2WA 3Q84A 4G6QA 3T49A 5KBPA 1TQVA 3ER9B 4JL9A 3D2FA 3LLLA 3O3OB 5C5BB 2ND1A 3ERCC 3DDFA 3BVVA 4R5GA 2Z8YA 2EWFA 1GN9A 3M3WA 1R33A 2ALWA 2O0I1 1OA0A 3EJQA 4IM2A 3T4AG 3B52X 4AZ5A 3LVTA 4H8SA 3I04A 3O3MB 4PO2A 2JNSA 3C7NA 3BUDA 4NSWA 3DDGA 4IWPA 4ATMA 1HWWA 3D50A 3D2EA 3LMFA 3QWEA 4IM0A 4R5IA 4AZ7A 4E81A 3SOGA 3HAIA 4EZPA 1UPXA 1GNTA 4H6IA 4JNFA 3ZEDA 4AKVA 2JNKA 2F18A 4AZCB 3HAHA 2V0OA 1O7DB 2YL6A 4HR1B 2MI7A 5TKYA 2Z0NA 3EJPA 1X03A 3O3NB 1WDZA 3QA8A 1QX1A 4HY9A 2ND0A 3CVRA 1QWUA 3ABHA 4D8JA 3BLBA 4EZWA 3DX1A 2ELBA 3VEBA 1PS3A 4EZVA 3HAJA 1QWNA 1DKXA 2RAIA 3QE6A 3F7WA 2QFFA 2YLLA 2FYVA 4JLCA 3QNIA 2EX3B 1I4TA 2FICA 2WYIA 2YL5A 2NCZA 2F7RA 4FZPA 4FZSA 2RAJA 2PMRA 5E84A 5FLEX 3I39X 3D52A 3KDRA 5C5BA 4M0MA 2YIVX 4B9QA 4EZOA 3VEAA 1LQ7A 2C08A 1I49A 2N3KA 2YKTA 4FZOA
chains in the Genus database with same CATH topology
2RAKA 3HAHA 2V0OA 1X04A 4I1QA 2EFLA 3OK8A 3CAZA 2Z0NA 1X03A 1ZWWA 1WDZA 1URUA 4WPEA 3PLTA 3Q84A 3I2WA 1I4DA 3LLLA 5C5BB 2D4CA 2ELBA 4BNEA 3HAJA 3M3WA 2Q13A 2RAIA 4DCNC 2Q12A 2X3WA 3QE6A 4NQIA 4AVMA 2X3VA 3QNIA 2YKTA 1I4TA 1I4LA 2FICA 2Z0OA 4H8SA 2X3XA 4FZSA 4WPCA 3G9GA 4DYLA 2RAJA 4NSWA 3ACOA 3DYTA 2Z0VA 4ATMA 3QWEA 5C5BA 3Q0KA 3SOGA 3HAIA 3SYVA 2D1LA 2EFKA 2C08A 1I49A 3ABHA 1Y2OA 4AKVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RAK A;  3HAH A;  2V0O A;  1X04 A;  4I1Q A;  2EFL A;  3OK8 A;  3CAZ A;  2Z0N A;  1X03 A;  1ZWW A;  1WDZ A;  1URU A;  4WPE A;  3PLT A;  3Q84 A;  3I2W A;  1I4D A;  3LLL A;  5C5B B;  2D4C A;  2ELB A;  4BNE A;  3HAJ A;  3M3W A;  2Q13 A;  2RAI A;  4DCN C;  2Q12 A;  2X3W A;  3QE6 A;  4NQI A;  4AVM A;  2X3V A;  3QNI A;  2YKT A;  1I4T A;  1I4L A;  2FIC A;  2Z0O A;  4H8S A;  2X3X A;  4FZS A;  4WPC A;  3G9G A;  4DYL A;  2RAJ A;  4NSW A;  3ACO A;  3DYT A;  2Z0V A;  4ATM A;  3QWE A;  5C5B A;  3Q0K A;  3SOG A;  3HAI A;  3SYV A;  2D1L A;  2EFK A;  2C08 A;  1I49 A;  3ABH A;  1Y2O A;  4AKV A; 
#chains in the Genus database with same CATH topology
 2KHO A;  1OAO A;  1W9M A;  2RT6 A;  3CZS A;  3CZN A;  4I1Q A;  3I01 A;  4HYB A;  2EFL A;  3QNJ A;  4HR1 A;  3RPM A;  4NPH A;  3CAZ A;  4EZX A;  2PY6 A;  3DPO A;  1URU A;  1E2U A;  4JWC A;  1I4D A;  3DPQ A;  1MJG A;  1GNL A;  4JWD A;  1TQT A;  2OBL A;  2QKW A;  3DPP A;  4JWE A;  3OWG A;  3BUQ A;  3T48 A;  3BVX A;  1HXK A;  1ZYL A;  1TQW A;  1E1D A;  2Q12 A;  2X3W A;  4AVM A;  2GAF D;  2LM0 A;  1DKZ A;  4JN4 A;  3KAW A;  4KIK A;  2YI8 A;  4F01 A;  3BUB A;  2OBM A;  2WYH A;  2QXL A;  3DYT A;  3DX4 A;  5FIG A;  3A98 A;  4F00 A;  3Q0K A;  3L3P A;  4EZS A;  2D1L A;  2EFK A;  3D4Y A;  3GI7 A;  4E3C A;  1Y2O A;  2YL8 A;  2Z0O A;  1O7D C;  3CV5 A;  3D4Z A;  1OA1 A;  4JNE A;  3T46 A;  2RAK A;  4AZC A;  4EZU A;  3D51 A;  3VKH A;  4UDY X;  3T47 A;  3KAV A;  4H6H A;  1R34 A;  2YI9 A;  2YIA A;  4IW0 A;  4AZB A;  1U00 A;  1ZWW A;  3EJR A;  2YL9 A;  4WPE A;  1SU7 A;  1DKY A;  3EJU A;  2ZXQ A;  4EZT A;  2WIN M;  3B53 X;  3OHX M;  1R5E A;  3EJS A;  4JWI A;  4IWQ A;  4EZN A;  1SU8 A;  2D4C A;  2GF4 A;  2F7P A;  2F7O A;  4EZZ A;  4BNE A;  3L3O M;  2LXY A;  2OO2 A;  4IM3 A;  2OW6 A;  3CKD A;  3ER8 C;  2Q13 A;  4DCN C;  2OZN B;  4AZI A;  1TQU A;  1YWM A;  3DX0 A;  3BUP A;  2X5C A;  4KIK B;  4NQI A;  1SUF A;  4AZH A;  2X3V A;  1I4L A;  2F7Q A;  3BVT A;  1E9V A;  2X3X A;  4R5K A;  4WPC A;  4AZ6 A;  3G9G A;  4DYL A;  1JQK A;  3FD9 A;  3RV0 A;  3ACO A;  2Z0V A;  1SU6 A;  1TQS A;  2GA9 D;  3BUI A;  1HTY A;  3DX3 A;  2F1B A;  3SYV A;  4R5J A;  2F1A A;  3DX2 A;  4EZR A;  4AZG A;  4FM3 A;  2OW7 A;  3EJT A;  4R5L A;  3BVU A;  4UDX X;  3RV1 A;  1X04 A;  3OK8 A;  4IWO A;  3UIT A;  4EZY A;  4EZQ A;  2YIB A;  2YLA A;  3BVW A;  3B51 X;  3PLT A;  3I2W A;  3Q84 A;  4G6Q A;  3T49 A;  5KBP A;  1TQV A;  3ER9 B;  4JL9 A;  3D2F A;  3LLL A;  3O3O B;  5C5B B;  2ND1 A;  3ERC C;  3DDF A;  3BVV A;  4R5G A;  2Z8Y A;  2EWF A;  1GN9 A;  3M3W A;  1R33 A;  2ALW A;  2O0I 1;  1OA0 A;  3EJQ A;  4IM2 A;  3T4A G;  3B52 X;  4AZ5 A;  3LVT A;  4H8S A;  3I04 A;  3O3M B;  4PO2 A;  2JNS A;  3C7N A;  3BUD A;  4NSW A;  3DDG A;  4IWP A;  4ATM A;  1HWW A;  3D50 A;  3D2E A;  3LMF A;  3QWE A;  4IM0 A;  4R5I A;  4AZ7 A;  4E81 A;  3SOG A;  3HAI A;  4EZP A;  1UPX A;  1GNT A;  4H6I A;  4JNF A;  3ZED A;  4AKV A;  2JNK A;  2F18 A;  4AZC B;  3HAH A;  2V0O A;  1O7D B;  2YL6 A;  4HR1 B;  2MI7 A;  5TKY A;  2Z0N A;  3EJP A;  1X03 A;  3O3N B;  1WDZ A;  3QA8 A;  1QX1 A;  4HY9 A;  2ND0 A;  3CVR A;  1QWU A;  3ABH A;  4D8J A;  3BLB A;  4EZW A;  3DX1 A;  2ELB A;  3VEB A;  1PS3 A;  4EZV A;  3HAJ A;  1QWN A;  1DKX A;  2RAI A;  3QE6 A;  3F7W A;  2QFF A;  2YLL A;  2FYV A;  4JLC A;  3QNI A;  2EX3 B;  1I4T A;  2FIC A;  2WYI A;  2YL5 A;  2NCZ A;  2F7R A;  4FZP A;  4FZS A;  2RAJ A;  2PMR A;  5E84 A;  5FLE X;  3I39 X;  3D52 A;  3KDR A;  5C5B A;  4M0M A;  2YIV X;  4B9Q A;  4EZO A;  3VEA A;  1LQ7 A;  2C08 A;  1I49 A;  2N3K A;  2YKT A;  4FZO A; 
#chains in the Genus database with same CATH homology
 2RAK A;  3HAH A;  2V0O A;  1X04 A;  4I1Q A;  2EFL A;  3OK8 A;  3CAZ A;  2Z0N A;  1X03 A;  1ZWW A;  1WDZ A;  1URU A;  4WPE A;  3PLT A;  3Q84 A;  3I2W A;  1I4D A;  3LLL A;  5C5B B;  2D4C A;  2ELB A;  4BNE A;  3HAJ A;  3M3W A;  2Q13 A;  2RAI A;  4DCN C;  2Q12 A;  2X3W A;  3QE6 A;  4NQI A;  4AVM A;  2X3V A;  3QNI A;  2YKT A;  1I4T A;  1I4L A;  2FIC A;  2Z0O A;  4H8S A;  2X3X A;  4FZS A;  4WPC A;  3G9G A;  4DYL A;  2RAJ A;  4NSW A;  3ACO A;  3DYT A;  2Z0V A;  4ATM A;  3QWE A;  5C5B A;  3Q0K A;  3SOG A;  3HAI A;  3SYV A;  2D1L A;  2EFK A;  2C08 A;  1I49 A;  3ABH A;  1Y2O A;  4AKV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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