4CD2A

Ligand induced conformational changes in the crystal structures of pneumocystis carinii dihydrofolate reductase complexes with folate and nadp+
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
202
structure length
202
Chain Sequence
KSLTLIVALTTSYGIGRSNSLPWKLKKEISYFKRVTSFVPTFDSFESMNVVLMGRKTWESIPLQFRPLKGRINVVITRNESLDLGNGIHSAKSLDHALELLYRTYGSESSVQINRIFVIGGAQLYKAAMDHPKLDRIMATIIYKDIHCDVFFPLKFRDKEWSSVWKKEKHSDLESWVGTKVPHGKINEDGFDYEFEMWTRDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Ligand-induced conformational changes in the crystal structures of Pneumocystis carinii dihydrofolate reductase complexes with folate and NADP+.
pubmed doi rcsb
molecule keywords DIHYDROFOLATE REDUCTASE
molecule tags Oxidoreductase
source organism Pneumocystis carinii
total genus 56
structure length 202
sequence length 202
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1999-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4cd2A00
2L28A 3QLZA 4FHBA 2ITHA 1HFQA 3KGYA 3NXYA 4KJKA 4KD7A 4P68A 4KM0A 5HQYA 2QK8A 4X5JA 2KGKA 3FYWX 3EX8A 4HA9A 5HUIA 3FYVX 2BLAA 3F0QX 4G95A 3NZAX 3CLBA 1CZ3A 2W3VA 1J3JA 3QYLA 4EILA 4HOEA 3DG8A 5E8QA 4Q6AA 5HSUA 3SGYA 1AOEA 1DR7A 5HSRA 7DFRA 1TDRA 5HT4A 4G3MA 2HM9A 5HPBA 1RX7A 3NRRA 5ECXA 3SRUX 3QYOA 1HFRA 3GI2A 4ECKA 1AI9A 4NX7A 4PSYA 3FY9X 4QHVA 5EAJA 2FZIA 4KAKA 3M08A 4M6LA 3FRFX 4KJJA 4HA7A 3TD8A 3EEJA 1LY3A 1SEJA 1RX5A 2W3AA 3FY8X 1DHJA 3SRSX 3K2HA 3EEMA 4I13A 1DLSA 3S7AA 3ZPCA 3KJSA 1LUDA 4OR7A 4KBNA 4PSTA 3I8AX 4KJLA 4G8ZX 1S3VA 4LEKX 3TQ8A 1PDBA 3EIGA 4NX6A 5HF2X 1VJ3A 5CC9A 1DRAA 3NXXA 3NXRA 1RA2A 3FQFA 4GH8A 3RG9A 1M78A 3INVA 1HFPA 4QLEA 3S9UA 2W9SA 3QLSA 2HXVA 1DR3A 1RF7A 3F0SX 1DAJA 4CD2A 1RX9A 4XRBA 5U27A 2W9GA 1IA4A 4KYAA 4DFRA 4DP3A 3QLYA 3CD2A 3R33A 5HT5A 1DR4A 4XE6X 3SA2A 3L3RA 2W3WA 2C2TA 4RGCA 3TQAA 3JVXA 1DR1A 3SR5X 3TQ9A 1DG5A 1JUVA 3EELA 1RA8A 4OSGA 3IRMA 1BOZA 3JWMA 2BLCA 1QZFA 3ROAA 2ZZAA 1RB3A 2CIGA 3DL6A 1S3YA 1RE7A 1DRFA 3CSEA 3F0BX 3FQCA 2HQPA 1DYHA 3IX9A 3NXOA 3LG4A 4KL9A 1DLRA 3NZCX 4M2XA 5HVBA 2OIPA 3M09A 4X5GA 1RX1A 1JOLA 3K47A 3GHCA 1LY4A 3VCOA 1M7AA 3JW3A 4X5FA 2D5NA 3FQZA 4LAGX 1DHFA 4KFJA 5HVEA 1RD7A 2AZNA 4QLGA 3SH2A 4ELEA 3DATA 1DISA 1MVTA 4I1NA 4P3QA 3FRDX 3QGTA 3F0VX 3FS6A 3FQVA 3KFYA 1DDRA 5HF0X 1S3UA 3NTZA 2INQA 3I3RA 4EIGA 3F8ZA 4XECX 2ANOA 1ZDRA 5U26A 3QL0A 3SA1A 3UM8A 1OHJA 2FZJA 2P4GA 1DHIA 3EEKA 2ANQA 2C2SA 4KY4A 1KLKA 1VDRA 4X5HA 3FRBX 4KY8A 3TQBA 4ELBA 4Q67A 4M6KA 4PDJA 1IA3A 1DDSA 3IRNA 1RX4A 2XW7A 3IROA 2O7PA 3NXVA 3HBBA 3GHVA 1DYRA 3JWFA 4LAHX 4IXFX 3QFXA 5JA3A 3NZBX 4PSSA 2FZHA 2G6VA 4IXED 4DDRA 6DFRA 2DRCA 1JOMA 3DGAA 1IA1A 4XT8A 1U72A 2JYBA 2W9TA 2BLBA 2D0KA 1DRBA 3SRWX 3S3VA 5FDAA 4M7UA 1U70A 3UM6A 4KM2A 1OHKA 8DFRA 1J3IA 4KEBA 1PD9A 1J3KA 3NXTA 4XT5A 3OCHA 1IA2A 1M79A 1PD8A 5DXVA 3FL9A 4P66A 3F0XX 3DL5A 2CD2A 1KMSA 1BZFA 3SAIA 4Q0DA 5JG0X 1RC4A 1DRHA 4H97A 1RH3A 3NZDA 1DYJA 3HJ3A 1MVSA 5CCCA 5HQZA 3JW5A 4KNEA 3E0BA 2B3ZA 3IA5A 1DIUA 4IXGX 1DG7A 3IA4A 4ELHA 4ELGA 3FQOA 1DR6A 2W9HA 1RA9A 1CD2A 4KLXA 2LF1A 3OAFA 4HOGA 3QLWA 4DPDA 4QJCA 3FL8A 3ZPGA 3F8YA 3KY8A 5DFRA 3F0UX 3JWCA 1D1GA 4EIZA 4DPHA 3QLRA 1RB2A 4FGHA 1DYIA 2DHFA 3JTWA 1DR2A 4PTJA 2W3BA 3F91A 4QLFA 4TU5X 3KJRA 3QLXA 4P3RA 4FGGA 2H2QA 4Q0EA 1DREA 1RA1A 3Q1HA 5ECCA 1RX3A 4HOFA 4LAEX 4X5IA 3K74A 2BL9A 4QJZD 4M7VA 1RA3A 3SRRX 4H98A 4M6JA 3D84X 4EJ1A 3UM5A 3N0HA 3D80A 1U71A 1DG8A 1S3WA 3SRQX 1YHOA 4XT4A 4ELFA 3DAUA 4XT6A 2GD9A 3NZ6X 1KMVA 3CL9A 3SQYX 3FRAX 3JSUA 3DFRA 1AO8A 1E26A 3K45A 3FQ0A 2OBCA 3FREX 3RO9A 3QG2A 3NZ9X 4H96A 1RX6A 1RX8A 4XT7A 3DRCA 3NU0A 3JWKA 1RG7A 5HI6A 1RX2A 4QI9A 1DF7A 4PTHA 3GHWA 4H95A 3QL3A 2W3MA 1DR5A 3GYFA
chains in the Genus database with same CATH superfamily
2L28A 3QLZA 4FHBA 2ITHA 1HFQA 3KGYA 3NXYA 4KJKA 4KD7A 4P68A 4KM0A 5HQYA 2QK8A 4X5JA 2KGKA 3FYWX 3EX8A 4HA9A 5HUIA 3FYVX 2BLAA 3F0QX 4G95A 3NZAX 3CLBA 1CZ3A 2W3VA 1J3JA 3QYLA 4EILA 4HOEA 3DG8A 5E8QA 4Q6AA 5HSUA 3SGYA 1AOEA 1DR7A 5HSRA 7DFRA 1TDRA 5HT4A 4G3MA 2HM9A 5HPBA 1RX7A 3NRRA 5ECXA 3SRUX 3QYOA 1HFRA 3GI2A 4ECKA 1AI9A 4NX7A 4PSYA 3FY9X 4QHVA 5EAJA 2FZIA 4KAKA 3M08A 4M6LA 3FRFX 4KJJA 4HA7A 3TD8A 3EEJA 1LY3A 1SEJA 1RX5A 2W3AA 3FY8X 1DHJA 3SRSX 3K2HA 3EEMA 4I13A 1DLSA 3S7AA 3ZPCA 3KJSA 1LUDA 4OR7A 4KBNA 4PSTA 3I8AX 4KJLA 4G8ZX 1S3VA 4LEKX 3TQ8A 1PDBA 3EIGA 4NX6A 5HF2X 1VJ3A 5CC9A 1DRAA 3NXXA 3NXRA 1RA2A 3FQFA 4GH8A 3RG9A 1M78A 3INVA 1HFPA 4QLEA 3S9UA 2W9SA 3QLSA 2HXVA 1DR3A 1RF7A 3F0SX 1DAJA 4CD2A 1RX9A 4XRBA 5U27A 2W9GA 1IA4A 4KYAA 4DFRA 4DP3A 3QLYA 3CD2A 3R33A 5HT5A 1DR4A 4XE6X 3SA2A 3L3RA 2W3WA 2C2TA 4RGCA 3TQAA 3JVXA 1DR1A 3SR5X 3TQ9A 1DG5A 1JUVA 3EELA 1RA8A 4OSGA 3IRMA 1BOZA 3JWMA 2BLCA 1QZFA 3ROAA 2ZZAA 1RB3A 2CIGA 3DL6A 1S3YA 1RE7A 1DRFA 3CSEA 3F0BX 3FQCA 2HQPA 1DYHA 3IX9A 3NXOA 3LG4A 4KL9A 1DLRA 3NZCX 4M2XA 5HVBA 2OIPA 3M09A 4X5GA 1RX1A 1JOLA 3K47A 3GHCA 1LY4A 3VCOA 1M7AA 3JW3A 4X5FA 2D5NA 3FQZA 4LAGX 1DHFA 4KFJA 5HVEA 1RD7A 2AZNA 4QLGA 3SH2A 4ELEA 3DATA 1DISA 1MVTA 4I1NA 4P3QA 3FRDX 3QGTA 3F0VX 3FS6A 3FQVA 3KFYA 1DDRA 5HF0X 1S3UA 3NTZA 2INQA 3I3RA 4EIGA 3F8ZA 4XECX 2ANOA 1ZDRA 5U26A 3QL0A 3SA1A 3UM8A 1OHJA 2FZJA 2P4GA 1DHIA 3EEKA 2ANQA 2C2SA 4KY4A 1KLKA 1VDRA 4X5HA 3FRBX 4KY8A 3TQBA 4ELBA 4Q67A 4M6KA 4PDJA 1IA3A 1DDSA 3IRNA 1RX4A 2XW7A 3IROA 2O7PA 3NXVA 3HBBA 3GHVA 1DYRA 3JWFA 4LAHX 4IXFX 3QFXA 5JA3A 3NZBX 4PSSA 2FZHA 2G6VA 4IXED 4DDRA 6DFRA 2DRCA 1JOMA 3DGAA 1IA1A 4XT8A 1U72A 2JYBA 2W9TA 2BLBA 2D0KA 1DRBA 3SRWX 3S3VA 5FDAA 4M7UA 1U70A 3UM6A 4KM2A 1OHKA 8DFRA 1J3IA 4KEBA 1PD9A 1J3KA 3NXTA 4XT5A 3OCHA 1IA2A 1M79A 1PD8A 5DXVA 3FL9A 4P66A 3F0XX 3DL5A 2CD2A 1KMSA 1BZFA 3SAIA 4Q0DA 5JG0X 1RC4A 1DRHA 4H97A 1RH3A 3NZDA 1DYJA 3HJ3A 1MVSA 5CCCA 5HQZA 3JW5A 4KNEA 3E0BA 2B3ZA 3IA5A 1DIUA 4IXGX 1DG7A 3IA4A 4ELHA 4ELGA 3FQOA 1DR6A 2W9HA 1RA9A 1CD2A 4KLXA 2LF1A 3OAFA 4HOGA 3QLWA 4DPDA 4QJCA 3FL8A 3ZPGA 3F8YA 3KY8A 5DFRA 3F0UX 3JWCA 1D1GA 4EIZA 4DPHA 3QLRA 1RB2A 4FGHA 1DYIA 2DHFA 3JTWA 1DR2A 4PTJA 2W3BA 3F91A 4QLFA 4TU5X 3KJRA 3QLXA 4P3RA 4FGGA 2H2QA 4Q0EA 1DREA 1RA1A 3Q1HA 5ECCA 1RX3A 4HOFA 4LAEX 4X5IA 3K74A 2BL9A 4QJZD 4M7VA 1RA3A 3SRRX 4H98A 4M6JA 3D84X 4EJ1A 3UM5A 3N0HA 3D80A 1U71A 1DG8A 1S3WA 3SRQX 1YHOA 4XT4A 4ELFA 3DAUA 4XT6A 2GD9A 3NZ6X 1KMVA 3CL9A 3SQYX 3FRAX 3JSUA 3DFRA 1AO8A 1E26A 3K45A 3FQ0A 2OBCA 3FREX 3RO9A 3QG2A 3NZ9X 4H96A 1RX6A 1RX8A 4XT7A 3DRCA 3NU0A 3JWKA 1RG7A 5HI6A 1RX2A 4QI9A 1DF7A 4PTHA 3GHWA 4H95A 3QL3A 2W3MA 1DR5A 3GYFA
chains in the Genus database with same CATH topology
2L28A 3QLZA 4FHBA 2ITHA 1HFQA 3KGYA 3NXYA 4KJKA 4KD7A 4P68A 4KM0A 5HQYA 2QK8A 4X5JA 2KGKA 3FYWX 3EX8A 4HA9A 5HUIA 3FYVX 2BLAA 3F0QX 4G95A 3NZAX 3CLBA 1CZ3A 2W3VA 1J3JA 3QYLA 4EILA 4HOEA 3DG8A 5E8QA 4Q6AA 5HSUA 3SGYA 1AOEA 1DR7A 5HSRA 7DFRA 1TDRA 5HT4A 4G3MA 2HM9A 5HPBA 1RX7A 3NRRA 5ECXA 3SRUX 3QYOA 1HFRA 3GI2A 4ECKA 1AI9A 4NX7A 4PSYA 3FY9X 4QHVA 5EAJA 2FZIA 4KAKA 3M08A 4M6LA 3FRFX 4KJJA 4HA7A 3TD8A 3EEJA 1LY3A 1SEJA 1RX5A 2W3AA 3FY8X 1DHJA 3SRSX 3K2HA 3EEMA 4I13A 1DLSA 3S7AA 3ZPCA 3KJSA 1LUDA 4OR7A 4KBNA 4PSTA 3I8AX 4KJLA 4G8ZX 1S3VA 4LEKX 3TQ8A 1PDBA 3EIGA 4NX6A 5HF2X 1VJ3A 5CC9A 1DRAA 3NXXA 3NXRA 1RA2A 3FQFA 4GH8A 3RG9A 1M78A 3INVA 1HFPA 4QLEA 3S9UA 2W9SA 3QLSA 2HXVA 1DR3A 1RF7A 3F0SX 1DAJA 4CD2A 1RX9A 4XRBA 5U27A 2W9GA 1IA4A 4KYAA 4DFRA 4DP3A 3QLYA 3CD2A 3R33A 5HT5A 1DR4A 4XE6X 3SA2A 3L3RA 2W3WA 2C2TA 4RGCA 3TQAA 3JVXA 1DR1A 3SR5X 3TQ9A 1DG5A 1JUVA 3EELA 1RA8A 4OSGA 3IRMA 1BOZA 3JWMA 2BLCA 1QZFA 3ROAA 2ZZAA 1RB3A 2CIGA 3DL6A 1S3YA 1RE7A 1DRFA 3CSEA 3F0BX 3FQCA 2HQPA 1DYHA 3IX9A 3NXOA 3LG4A 4KL9A 1DLRA 3NZCX 4M2XA 5HVBA 2OIPA 3M09A 4X5GA 1RX1A 1JOLA 3K47A 3GHCA 1LY4A 3VCOA 1M7AA 3JW3A 4X5FA 2D5NA 3FQZA 4LAGX 1DHFA 4KFJA 5HVEA 1RD7A 2AZNA 4QLGA 3SH2A 4ELEA 3DATA 1DISA 1MVTA 4I1NA 4P3QA 3FRDX 3QGTA 3F0VX 3FS6A 3FQVA 3KFYA 1DDRA 5HF0X 1S3UA 3NTZA 2INQA 3I3RA 4EIGA 3F8ZA 4XECX 2ANOA 1ZDRA 5U26A 3QL0A 3SA1A 3UM8A 1OHJA 2FZJA 2P4GA 1DHIA 3EEKA 2ANQA 2C2SA 4KY4A 1KLKA 1VDRA 4X5HA 3FRBX 4KY8A 3TQBA 4ELBA 4Q67A 4M6KA 4PDJA 1IA3A 1DDSA 3IRNA 1RX4A 2XW7A 3IROA 2O7PA 3NXVA 3HBBA 3GHVA 1DYRA 3JWFA 4LAHX 4IXFX 3QFXA 5JA3A 3NZBX 4PSSA 2FZHA 2G6VA 4IXED 4DDRA 6DFRA 2DRCA 1JOMA 3DGAA 1IA1A 4XT8A 1U72A 2JYBA 2W9TA 2BLBA 2D0KA 1DRBA 3SRWX 3S3VA 5FDAA 4M7UA 1U70A 3UM6A 4KM2A 1OHKA 8DFRA 1J3IA 4KEBA 1PD9A 1J3KA 3NXTA 4XT5A 3OCHA 1IA2A 1M79A 1PD8A 5DXVA 3FL9A 4P66A 3F0XX 3DL5A 2CD2A 1KMSA 1BZFA 3SAIA 4Q0DA 5JG0X 1RC4A 1DRHA 4H97A 1RH3A 3NZDA 1DYJA 3HJ3A 1MVSA 5CCCA 5HQZA 3JW5A 4KNEA 3E0BA 2B3ZA 3IA5A 1DIUA 4IXGX 1DG7A 3IA4A 4ELHA 4ELGA 3FQOA 1DR6A 2W9HA 1RA9A 1CD2A 4KLXA 2LF1A 3OAFA 4HOGA 3QLWA 4DPDA 4QJCA 3FL8A 3ZPGA 3F8YA 3KY8A 5DFRA 3F0UX 3JWCA 1D1GA 4EIZA 4DPHA 3QLRA 1RB2A 4FGHA 1DYIA 2DHFA 3JTWA 1DR2A 4PTJA 2W3BA 3F91A 4QLFA 4TU5X 3KJRA 3QLXA 4P3RA 4FGGA 2H2QA 4Q0EA 1DREA 1RA1A 3Q1HA 5ECCA 1RX3A 4HOFA 4LAEX 4X5IA 3K74A 2BL9A 4QJZD 4M7VA 1RA3A 3SRRX 4H98A 4M6JA 3D84X 4EJ1A 3UM5A 3N0HA 3D80A 1U71A 1DG8A 1S3WA 3SRQX 1YHOA 4XT4A 4ELFA 3DAUA 4XT6A 2GD9A 3NZ6X 1KMVA 3CL9A 3SQYX 3FRAX 3JSUA 3DFRA 1AO8A 1E26A 3K45A 3FQ0A 2OBCA 3FREX 3RO9A 3QG2A 3NZ9X 4H96A 1RX6A 1RX8A 4XT7A 3DRCA 3NU0A 3JWKA 1RG7A 5HI6A 1RX2A 4QI9A 1DF7A 4PTHA 3GHWA 4H95A 3QL3A 2W3MA 1DR5A 3GYFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L28 A;  3QLZ A;  4FHB A;  2ITH A;  1HFQ A;  3KGY A;  3NXY A;  4KJK A;  4KD7 A;  4P68 A;  4KM0 A;  5HQY A;  2QK8 A;  4X5J A;  2KGK A;  3FYW X;  3EX8 A;  4HA9 A;  5HUI A;  3FYV X;  2BLA A;  3F0Q X;  4G95 A;  3NZA X;  3CLB A;  1CZ3 A;  2W3V A;  1J3J A;  3QYL A;  4EIL A;  4HOE A;  3DG8 A;  5E8Q A;  4Q6A A;  5HSU A;  3SGY A;  1AOE A;  1DR7 A;  5HSR A;  7DFR A;  1TDR A;  5HT4 A;  4G3M A;  2HM9 A;  5HPB A;  1RX7 A;  3NRR A;  5ECX A;  3SRU X;  3QYO A;  1HFR A;  3GI2 A;  4ECK A;  1AI9 A;  4NX7 A;  4PSY A;  3FY9 X;  4QHV A;  5EAJ A;  2FZI A;  4KAK A;  3M08 A;  4M6L A;  3FRF X;  4KJJ A;  4HA7 A;  3TD8 A;  3EEJ A;  1LY3 A;  1SEJ A;  1RX5 A;  2W3A A;  3FY8 X;  1DHJ A;  3SRS X;  3K2H A;  3EEM A;  4I13 A;  1DLS A;  3S7A A;  3ZPC A;  3KJS A;  1LUD A;  4OR7 A;  4KBN A;  4PST A;  3I8A X;  4KJL A;  4G8Z X;  1S3V A;  4LEK X;  3TQ8 A;  1PDB A;  3EIG A;  4NX6 A;  5HF2 X;  1VJ3 A;  5CC9 A;  1DRA A;  3NXX A;  3NXR A;  1RA2 A;  3FQF A;  4GH8 A;  3RG9 A;  1M78 A;  3INV A;  1HFP A;  4QLE A;  3S9U A;  2W9S A;  3QLS A;  2HXV A;  1DR3 A;  1RF7 A;  3F0S X;  1DAJ A;  4CD2 A;  1RX9 A;  4XRB A;  5U27 A;  2W9G A;  1IA4 A;  4KYA A;  4DFR A;  4DP3 A;  3QLY A;  3CD2 A;  3R33 A;  5HT5 A;  1DR4 A;  4XE6 X;  3SA2 A;  3L3R A;  2W3W A;  2C2T A;  4RGC A;  3TQA A;  3JVX A;  1DR1 A;  3SR5 X;  3TQ9 A;  1DG5 A;  1JUV A;  3EEL A;  1RA8 A;  4OSG A;  3IRM A;  1BOZ A;  3JWM A;  2BLC A;  1QZF A;  3ROA A;  2ZZA A;  1RB3 A;  2CIG A;  3DL6 A;  1S3Y A;  1RE7 A;  1DRF A;  3CSE A;  3F0B X;  3FQC A;  2HQP A;  1DYH A;  3IX9 A;  3NXO A;  3LG4 A;  4KL9 A;  1DLR A;  3NZC X;  4M2X A;  5HVB A;  2OIP A;  3M09 A;  4X5G A;  1RX1 A;  1JOL A;  3K47 A;  3GHC A;  1LY4 A;  3VCO A;  1M7A A;  3JW3 A;  4X5F A;  2D5N A;  3FQZ A;  4LAG X;  1DHF A;  4KFJ A;  5HVE A;  1RD7 A;  2AZN A;  4QLG A;  3SH2 A;  4ELE A;  3DAT A;  1DIS A;  1MVT A;  4I1N A;  4P3Q A;  3FRD X;  3QGT A;  3F0V X;  3FS6 A;  3FQV A;  3KFY A;  1DDR A;  5HF0 X;  1S3U A;  3NTZ A;  2INQ A;  3I3R A;  4EIG A;  3F8Z A;  4XEC X;  2ANO A;  1ZDR A;  5U26 A;  3QL0 A;  3SA1 A;  3UM8 A;  1OHJ A;  2FZJ A;  2P4G A;  1DHI A;  3EEK A;  2ANQ A;  2C2S A;  4KY4 A;  1KLK A;  1VDR A;  4X5H A;  3FRB X;  4KY8 A;  3TQB A;  4ELB A;  4Q67 A;  4M6K A;  4PDJ A;  1IA3 A;  1DDS A;  3IRN A;  1RX4 A;  2XW7 A;  3IRO A;  2O7P A;  3NXV A;  3HBB A;  3GHV A;  1DYR A;  3JWF A;  4LAH X;  4IXF X;  3QFX A;  5JA3 A;  3NZB X;  4PSS A;  2FZH A;  2G6V A;  4IXE D;  4DDR A;  6DFR A;  2DRC A;  1JOM A;  3DGA A;  1IA1 A;  4XT8 A;  1U72 A;  2JYB A;  2W9T A;  2BLB A;  2D0K A;  1DRB A;  3SRW X;  3S3V A;  5FDA A;  4M7U A;  1U70 A;  3UM6 A;  4KM2 A;  1OHK A;  8DFR A;  1J3I A;  4KEB A;  1PD9 A;  1J3K A;  3NXT A;  4XT5 A;  3OCH A;  1IA2 A;  1M79 A;  1PD8 A;  5DXV A;  3FL9 A;  4P66 A;  3F0X X;  3DL5 A;  2CD2 A;  1KMS A;  1BZF A;  3SAI A;  4Q0D A;  5JG0 X;  1RC4 A;  1DRH A;  4H97 A;  1RH3 A;  3NZD A;  1DYJ A;  3HJ3 A;  1MVS A;  5CCC A;  5HQZ A;  3JW5 A;  4KNE A;  3E0B A;  2B3Z A;  3IA5 A;  1DIU A;  4IXG X;  1DG7 A;  3IA4 A;  4ELH A;  4ELG A;  3FQO A;  1DR6 A;  2W9H A;  1RA9 A;  1CD2 A;  4KLX A;  2LF1 A;  3OAF A;  4HOG A;  3QLW A;  4DPD A;  4QJC A;  3FL8 A;  3ZPG A;  3F8Y A;  3KY8 A;  5DFR A;  3F0U X;  3JWC A;  1D1G A;  4EIZ A;  4DPH A;  3QLR A;  1RB2 A;  4FGH A;  1DYI A;  2DHF A;  3JTW A;  1DR2 A;  4PTJ A;  2W3B A;  3F91 A;  4QLF A;  4TU5 X;  3KJR A;  3QLX A;  4P3R A;  4FGG A;  2H2Q A;  4Q0E A;  1DRE A;  1RA1 A;  3Q1H A;  5ECC A;  1RX3 A;  4HOF A;  4LAE X;  4X5I A;  3K74 A;  2BL9 A;  4QJZ D;  4M7V A;  1RA3 A;  3SRR X;  4H98 A;  4M6J A;  3D84 X;  4EJ1 A;  3UM5 A;  3N0H A;  3D80 A;  1U71 A;  1DG8 A;  1S3W A;  3SRQ X;  1YHO A;  4XT4 A;  4ELF A;  3DAU A;  4XT6 A;  2GD9 A;  3NZ6 X;  1KMV A;  3CL9 A;  3SQY X;  3FRA X;  3JSU A;  3DFR A;  1AO8 A;  1E26 A;  3K45 A;  3FQ0 A;  2OBC A;  3FRE X;  3RO9 A;  3QG2 A;  3NZ9 X;  4H96 A;  1RX6 A;  1RX8 A;  4XT7 A;  3DRC A;  3NU0 A;  3JWK A;  1RG7 A;  5HI6 A;  1RX2 A;  4QI9 A;  1DF7 A;  4PTH A;  3GHW A;  4H95 A;  3QL3 A;  2W3M A;  1DR5 A;  3GYF A; 
#chains in the Genus database with same CATH topology
 2L28 A;  3QLZ A;  4FHB A;  2ITH A;  1HFQ A;  3KGY A;  3NXY A;  4KJK A;  4KD7 A;  4P68 A;  4KM0 A;  5HQY A;  2QK8 A;  4X5J A;  2KGK A;  3FYW X;  3EX8 A;  4HA9 A;  5HUI A;  3FYV X;  2BLA A;  3F0Q X;  4G95 A;  3NZA X;  3CLB A;  1CZ3 A;  2W3V A;  1J3J A;  3QYL A;  4EIL A;  4HOE A;  3DG8 A;  5E8Q A;  4Q6A A;  5HSU A;  3SGY A;  1AOE A;  1DR7 A;  5HSR A;  7DFR A;  1TDR A;  5HT4 A;  4G3M A;  2HM9 A;  5HPB A;  1RX7 A;  3NRR A;  5ECX A;  3SRU X;  3QYO A;  1HFR A;  3GI2 A;  4ECK A;  1AI9 A;  4NX7 A;  4PSY A;  3FY9 X;  4QHV A;  5EAJ A;  2FZI A;  4KAK A;  3M08 A;  4M6L A;  3FRF X;  4KJJ A;  4HA7 A;  3TD8 A;  3EEJ A;  1LY3 A;  1SEJ A;  1RX5 A;  2W3A A;  3FY8 X;  1DHJ A;  3SRS X;  3K2H A;  3EEM A;  4I13 A;  1DLS A;  3S7A A;  3ZPC A;  3KJS A;  1LUD A;  4OR7 A;  4KBN A;  4PST A;  3I8A X;  4KJL A;  4G8Z X;  1S3V A;  4LEK X;  3TQ8 A;  1PDB A;  3EIG A;  4NX6 A;  5HF2 X;  1VJ3 A;  5CC9 A;  1DRA A;  3NXX A;  3NXR A;  1RA2 A;  3FQF A;  4GH8 A;  3RG9 A;  1M78 A;  3INV A;  1HFP A;  4QLE A;  3S9U A;  2W9S A;  3QLS A;  2HXV A;  1DR3 A;  1RF7 A;  3F0S X;  1DAJ A;  4CD2 A;  1RX9 A;  4XRB A;  5U27 A;  2W9G A;  1IA4 A;  4KYA A;  4DFR A;  4DP3 A;  3QLY A;  3CD2 A;  3R33 A;  5HT5 A;  1DR4 A;  4XE6 X;  3SA2 A;  3L3R A;  2W3W A;  2C2T A;  4RGC A;  3TQA A;  3JVX A;  1DR1 A;  3SR5 X;  3TQ9 A;  1DG5 A;  1JUV A;  3EEL A;  1RA8 A;  4OSG A;  3IRM A;  1BOZ A;  3JWM A;  2BLC A;  1QZF A;  3ROA A;  2ZZA A;  1RB3 A;  2CIG A;  3DL6 A;  1S3Y A;  1RE7 A;  1DRF A;  3CSE A;  3F0B X;  3FQC A;  2HQP A;  1DYH A;  3IX9 A;  3NXO A;  3LG4 A;  4KL9 A;  1DLR A;  3NZC X;  4M2X A;  5HVB A;  2OIP A;  3M09 A;  4X5G A;  1RX1 A;  1JOL A;  3K47 A;  3GHC A;  1LY4 A;  3VCO A;  1M7A A;  3JW3 A;  4X5F A;  2D5N A;  3FQZ A;  4LAG X;  1DHF A;  4KFJ A;  5HVE A;  1RD7 A;  2AZN A;  4QLG A;  3SH2 A;  4ELE A;  3DAT A;  1DIS A;  1MVT A;  4I1N A;  4P3Q A;  3FRD X;  3QGT A;  3F0V X;  3FS6 A;  3FQV A;  3KFY A;  1DDR A;  5HF0 X;  1S3U A;  3NTZ A;  2INQ A;  3I3R A;  4EIG A;  3F8Z A;  4XEC X;  2ANO A;  1ZDR A;  5U26 A;  3QL0 A;  3SA1 A;  3UM8 A;  1OHJ A;  2FZJ A;  2P4G A;  1DHI A;  3EEK A;  2ANQ A;  2C2S A;  4KY4 A;  1KLK A;  1VDR A;  4X5H A;  3FRB X;  4KY8 A;  3TQB A;  4ELB A;  4Q67 A;  4M6K A;  4PDJ A;  1IA3 A;  1DDS A;  3IRN A;  1RX4 A;  2XW7 A;  3IRO A;  2O7P A;  3NXV A;  3HBB A;  3GHV A;  1DYR A;  3JWF A;  4LAH X;  4IXF X;  3QFX A;  5JA3 A;  3NZB X;  4PSS A;  2FZH A;  2G6V A;  4IXE D;  4DDR A;  6DFR A;  2DRC A;  1JOM A;  3DGA A;  1IA1 A;  4XT8 A;  1U72 A;  2JYB A;  2W9T A;  2BLB A;  2D0K A;  1DRB A;  3SRW X;  3S3V A;  5FDA A;  4M7U A;  1U70 A;  3UM6 A;  4KM2 A;  1OHK A;  8DFR A;  1J3I A;  4KEB A;  1PD9 A;  1J3K A;  3NXT A;  4XT5 A;  3OCH A;  1IA2 A;  1M79 A;  1PD8 A;  5DXV A;  3FL9 A;  4P66 A;  3F0X X;  3DL5 A;  2CD2 A;  1KMS A;  1BZF A;  3SAI A;  4Q0D A;  5JG0 X;  1RC4 A;  1DRH A;  4H97 A;  1RH3 A;  3NZD A;  1DYJ A;  3HJ3 A;  1MVS A;  5CCC A;  5HQZ A;  3JW5 A;  4KNE A;  3E0B A;  2B3Z A;  3IA5 A;  1DIU A;  4IXG X;  1DG7 A;  3IA4 A;  4ELH A;  4ELG A;  3FQO A;  1DR6 A;  2W9H A;  1RA9 A;  1CD2 A;  4KLX A;  2LF1 A;  3OAF A;  4HOG A;  3QLW A;  4DPD A;  4QJC A;  3FL8 A;  3ZPG A;  3F8Y A;  3KY8 A;  5DFR A;  3F0U X;  3JWC A;  1D1G A;  4EIZ A;  4DPH A;  3QLR A;  1RB2 A;  4FGH A;  1DYI A;  2DHF A;  3JTW A;  1DR2 A;  4PTJ A;  2W3B A;  3F91 A;  4QLF A;  4TU5 X;  3KJR A;  3QLX A;  4P3R A;  4FGG A;  2H2Q A;  4Q0E A;  1DRE A;  1RA1 A;  3Q1H A;  5ECC A;  1RX3 A;  4HOF A;  4LAE X;  4X5I A;  3K74 A;  2BL9 A;  4QJZ D;  4M7V A;  1RA3 A;  3SRR X;  4H98 A;  4M6J A;  3D84 X;  4EJ1 A;  3UM5 A;  3N0H A;  3D80 A;  1U71 A;  1DG8 A;  1S3W A;  3SRQ X;  1YHO A;  4XT4 A;  4ELF A;  3DAU A;  4XT6 A;  2GD9 A;  3NZ6 X;  1KMV A;  3CL9 A;  3SQY X;  3FRA X;  3JSU A;  3DFR A;  1AO8 A;  1E26 A;  3K45 A;  3FQ0 A;  2OBC A;  3FRE X;  3RO9 A;  3QG2 A;  3NZ9 X;  4H96 A;  1RX6 A;  1RX8 A;  4XT7 A;  3DRC A;  3NU0 A;  3JWK A;  1RG7 A;  5HI6 A;  1RX2 A;  4QI9 A;  1DF7 A;  4PTH A;  3GHW A;  4H95 A;  3QL3 A;  2W3M A;  1DR5 A;  3GYF A; 
#chains in the Genus database with same CATH homology
 2L28 A;  3QLZ A;  4FHB A;  2ITH A;  1HFQ A;  3KGY A;  3NXY A;  4KJK A;  4KD7 A;  4P68 A;  4KM0 A;  5HQY A;  2QK8 A;  4X5J A;  2KGK A;  3FYW X;  3EX8 A;  4HA9 A;  5HUI A;  3FYV X;  2BLA A;  3F0Q X;  4G95 A;  3NZA X;  3CLB A;  1CZ3 A;  2W3V A;  1J3J A;  3QYL A;  4EIL A;  4HOE A;  3DG8 A;  5E8Q A;  4Q6A A;  5HSU A;  3SGY A;  1AOE A;  1DR7 A;  5HSR A;  7DFR A;  1TDR A;  5HT4 A;  4G3M A;  2HM9 A;  5HPB A;  1RX7 A;  3NRR A;  5ECX A;  3SRU X;  3QYO A;  1HFR A;  3GI2 A;  4ECK A;  1AI9 A;  4NX7 A;  4PSY A;  3FY9 X;  4QHV A;  5EAJ A;  2FZI A;  4KAK A;  3M08 A;  4M6L A;  3FRF X;  4KJJ A;  4HA7 A;  3TD8 A;  3EEJ A;  1LY3 A;  1SEJ A;  1RX5 A;  2W3A A;  3FY8 X;  1DHJ A;  3SRS X;  3K2H A;  3EEM A;  4I13 A;  1DLS A;  3S7A A;  3ZPC A;  3KJS A;  1LUD A;  4OR7 A;  4KBN A;  4PST A;  3I8A X;  4KJL A;  4G8Z X;  1S3V A;  4LEK X;  3TQ8 A;  1PDB A;  3EIG A;  4NX6 A;  5HF2 X;  1VJ3 A;  5CC9 A;  1DRA A;  3NXX A;  3NXR A;  1RA2 A;  3FQF A;  4GH8 A;  3RG9 A;  1M78 A;  3INV A;  1HFP A;  4QLE A;  3S9U A;  2W9S A;  3QLS A;  2HXV A;  1DR3 A;  1RF7 A;  3F0S X;  1DAJ A;  4CD2 A;  1RX9 A;  4XRB A;  5U27 A;  2W9G A;  1IA4 A;  4KYA A;  4DFR A;  4DP3 A;  3QLY A;  3CD2 A;  3R33 A;  5HT5 A;  1DR4 A;  4XE6 X;  3SA2 A;  3L3R A;  2W3W A;  2C2T A;  4RGC A;  3TQA A;  3JVX A;  1DR1 A;  3SR5 X;  3TQ9 A;  1DG5 A;  1JUV A;  3EEL A;  1RA8 A;  4OSG A;  3IRM A;  1BOZ A;  3JWM A;  2BLC A;  1QZF A;  3ROA A;  2ZZA A;  1RB3 A;  2CIG A;  3DL6 A;  1S3Y A;  1RE7 A;  1DRF A;  3CSE A;  3F0B X;  3FQC A;  2HQP A;  1DYH A;  3IX9 A;  3NXO A;  3LG4 A;  4KL9 A;  1DLR A;  3NZC X;  4M2X A;  5HVB A;  2OIP A;  3M09 A;  4X5G A;  1RX1 A;  1JOL A;  3K47 A;  3GHC A;  1LY4 A;  3VCO A;  1M7A A;  3JW3 A;  4X5F A;  2D5N A;  3FQZ A;  4LAG X;  1DHF A;  4KFJ A;  5HVE A;  1RD7 A;  2AZN A;  4QLG A;  3SH2 A;  4ELE A;  3DAT A;  1DIS A;  1MVT A;  4I1N A;  4P3Q A;  3FRD X;  3QGT A;  3F0V X;  3FS6 A;  3FQV A;  3KFY A;  1DDR A;  5HF0 X;  1S3U A;  3NTZ A;  2INQ A;  3I3R A;  4EIG A;  3F8Z A;  4XEC X;  2ANO A;  1ZDR A;  5U26 A;  3QL0 A;  3SA1 A;  3UM8 A;  1OHJ A;  2FZJ A;  2P4G A;  1DHI A;  3EEK A;  2ANQ A;  2C2S A;  4KY4 A;  1KLK A;  1VDR A;  4X5H A;  3FRB X;  4KY8 A;  3TQB A;  4ELB A;  4Q67 A;  4M6K A;  4PDJ A;  1IA3 A;  1DDS A;  3IRN A;  1RX4 A;  2XW7 A;  3IRO A;  2O7P A;  3NXV A;  3HBB A;  3GHV A;  1DYR A;  3JWF A;  4LAH X;  4IXF X;  3QFX A;  5JA3 A;  3NZB X;  4PSS A;  2FZH A;  2G6V A;  4IXE D;  4DDR A;  6DFR A;  2DRC A;  1JOM A;  3DGA A;  1IA1 A;  4XT8 A;  1U72 A;  2JYB A;  2W9T A;  2BLB A;  2D0K A;  1DRB A;  3SRW X;  3S3V A;  5FDA A;  4M7U A;  1U70 A;  3UM6 A;  4KM2 A;  1OHK A;  8DFR A;  1J3I A;  4KEB A;  1PD9 A;  1J3K A;  3NXT A;  4XT5 A;  3OCH A;  1IA2 A;  1M79 A;  1PD8 A;  5DXV A;  3FL9 A;  4P66 A;  3F0X X;  3DL5 A;  2CD2 A;  1KMS A;  1BZF A;  3SAI A;  4Q0D A;  5JG0 X;  1RC4 A;  1DRH A;  4H97 A;  1RH3 A;  3NZD A;  1DYJ A;  3HJ3 A;  1MVS A;  5CCC A;  5HQZ A;  3JW5 A;  4KNE A;  3E0B A;  2B3Z A;  3IA5 A;  1DIU A;  4IXG X;  1DG7 A;  3IA4 A;  4ELH A;  4ELG A;  3FQO A;  1DR6 A;  2W9H A;  1RA9 A;  1CD2 A;  4KLX A;  2LF1 A;  3OAF A;  4HOG A;  3QLW A;  4DPD A;  4QJC A;  3FL8 A;  3ZPG A;  3F8Y A;  3KY8 A;  5DFR A;  3F0U X;  3JWC A;  1D1G A;  4EIZ A;  4DPH A;  3QLR A;  1RB2 A;  4FGH A;  1DYI A;  2DHF A;  3JTW A;  1DR2 A;  4PTJ A;  2W3B A;  3F91 A;  4QLF A;  4TU5 X;  3KJR A;  3QLX A;  4P3R A;  4FGG A;  2H2Q A;  4Q0E A;  1DRE A;  1RA1 A;  3Q1H A;  5ECC A;  1RX3 A;  4HOF A;  4LAE X;  4X5I A;  3K74 A;  2BL9 A;  4QJZ D;  4M7V A;  1RA3 A;  3SRR X;  4H98 A;  4M6J A;  3D84 X;  4EJ1 A;  3UM5 A;  3N0H A;  3D80 A;  1U71 A;  1DG8 A;  1S3W A;  3SRQ X;  1YHO A;  4XT4 A;  4ELF A;  3DAU A;  4XT6 A;  2GD9 A;  3NZ6 X;  1KMV A;  3CL9 A;  3SQY X;  3FRA X;  3JSU A;  3DFR A;  1AO8 A;  1E26 A;  3K45 A;  3FQ0 A;  2OBC A;  3FRE X;  3RO9 A;  3QG2 A;  3NZ9 X;  4H96 A;  1RX6 A;  1RX8 A;  4XT7 A;  3DRC A;  3NU0 A;  3JWK A;  1RG7 A;  5HI6 A;  1RX2 A;  4QI9 A;  1DF7 A;  4PTH A;  3GHW A;  4H95 A;  3QL3 A;  2W3M A;  1DR5 A;  3GYF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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