4DFRA

Crystal structures of escherichia coli and lactobacillus casei dihydrofolate reductase refined at 1.7 angstroms resolution. i. general features and binding of methotrexate
Total Genus 43
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFKILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.
pubmed rcsb
molecule keywords DIHYDROFOLATE REDUCTASE
molecule tags Oxidoreductase
source organism Escherichia coli
total genus 43
structure length 159
sequence length 159
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1982-06-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4dfrA00
4DDRA 1DHIA 1DLRA 4P68A 1QZFA 4HA9A 4P66A 3IX9A 4HOGA 1AOEA 1OHKA 2HQPA 1MVTA 2BLBA 3IROA 3NZBX 4EILA 1AO8A 1DYHA 4ELBA 1RD7A 4ELFA 5HUIA 1E26A 1DR5A 4QHVA 3FRAX 3K74A 1RA3A 4KEBA 1HFPA 2W3BA 1RX3A 3GHVA 2FZIA 3INVA 3SR5X 4X5HA 2W3VA 3TQ8A 3SA2A 4IXFX 2CIGA 4EIZA 4KL9A 3FRDX 1DHFA 4PTHA 3K2HA 3QL0A 5DFRA 3M08A 4OR7A 1JOLA 5HVBA 1YHOA 3FQCA 1J3JA 3GHWA 5ECXA 3FYWX 4Q0DA 1D1GA 1MVSA 2KGKA 1RX8A 3KFYA 4XT6A 7DFRA 2LF1A 3NXTA 3S7AA 5U26A 3F0BX 2CD2A 3DL5A 3EX8A 2W9SA 1SEJA 1S3VA 4DPHA 3JVXA 4LAHX 3R33A 4QJZD 1DYIA 3CL9A 2BLCA 3JTWA 4DP3A 3GI2A 4X5FA 4QI9A 1M78A 3JWKA 1RX9A 2W3MA 4M6LA 2W9GA 1DR6A 4H96A 1U71A 1DR2A 2DRCA 1IA3A 1OHJA 2ANQA 1J3IA 3NXYA 3SA1A 3QFXA 4G3MA 4NX6A 2BLAA 4X5JA 1RA2A 4QLGA 1HFRA 4XT4A 3NXRA 3QG2A 1DG8A 3FQZA 4M6JA 1JUVA 4KNEA 2H2QA 2ITHA 2OBCA 4QLFA 3OAFA 5HVEA 1U70A 2O7PA 2JYBA 3F8ZA 3FL9A 4ECKA 4X5IA 1BOZA 1CD2A 3JWCA 3NXXA 1PD9A 1IA2A 3SRQX 4KAKA 4ELHA 2OIPA 3FQOA 3IA5A 3Q1HA 2G6VA 3CD2A 1DG7A 3HJ3A 1DDSA 3HBBA 1DG5A 2B3ZA 2D0KA 5HT4A 3EELA 3JWMA 3DGAA 1RX7A 3NTZA 3DATA 1DISA 3EEKA 1DRBA 1VJ3A 3SQYX 3IRNA 1DLSA 1DF7A 1M79A 2W3WA 2D5NA 3RO9A 4XECX 3LG4A 3F0VX 3FY8X 1DRHA 1DREA 4M6KA 4XRBA 2QK8A 4HOEA 3EEMA 4G8ZX 1PD8A 1S3WA 3JW5A 3N0HA 2C2SA 4M2XA 4P3RA 4M7UA 3QYLA 4FGGA 1JOMA 1DR1A 1DR3A 2ANOA 2FZJA 4KYAA 3K45A 1S3YA 4KLXA 3SRUX 4KJLA 3NRRA 3DRCA 3CSEA 1RB3A 3FQ0A 3EEJA 3GHCA 1LUDA 4XT8A 4KBNA 4KD7A 4HA7A 4KY8A 4ELGA 4GH8A 3FQVA 1RA1A 3FQFA 1BZFA 5ECCA 3F0UX 4IXED 5HF0X 4PTJA 3ROAA 3QGTA 1J3KA 2HXVA 3FY9X 3M09A 4DFRA 3NZAX 3DG8A 3K47A 4KJJA 5CCCA 3NZDA 8DFRA 4XT7A 4DPDA 3FREX 3SH2A 2W9HA 3NXVA 4LAGX 4XT5A 4NX7A 5FDAA 4X5GA 4KM2A 3SRRX 5CC9A 3L3RA 4H97A 3DFRA 4H98A 5U27A 4KFJA 4EIGA 3GYFA 3KGYA 5HSUA 3FRBX 3QLYA 3FS6A 4LEKX 3S9UA 3TQ9A 3DAUA 3TD8A 4QLEA 3QLRA 1RF7A 1S3UA 3JWFA 4QJCA 1DRFA 1DDRA 1DYRA 3QLSA 5HI6A 3IRMA 3VCOA 1RC4A 1RG7A 4G95A 4KJKA 4M7VA 3D84X 4PSTA 1RB2A 2INQA 4P3QA 3NZCX 3ZPCA 1AI9A 3QLZA 3RG9A 1KLKA 3F91A 3EIGA 5DXVA 1RE7A 3TQBA 4TU5X 5HQYA 6DFRA 1CZ3A 3KJRA 5HSRA 3QL3A 4LAEX 3FYVX 1ZDRA 1DR4A 1VDRA 3TQAA 2ZZAA 3KJSA 4KM0A 4ELEA 4I13A 3QYOA 2C2TA 4FHBA 3JW3A 3F0XX 4RGCA 5HF2X 4Q67A 2XW7A 3UM6A 3SRWX 3F0SX 3KY8A 5HPBA 5EAJA 3QLXA 3SRSX 1RX1A 1RX5A 1IA4A 2W9TA 1HFQA 4PSSA 1IA1A 4XE6X 3UM8A 1LY4A 1DR7A 4Q0EA 1DHJA 1DAJA 1RX2A 3S3VA 1M7AA 1DRAA 3D80A 2BL9A 1LY3A 4CD2A 1TDRA 1DYJA 3I3RA 3OCHA 4KY4A 3FRFX 4IXGX 3NU0A 3QLWA 3DL6A 4Q6AA 5HQZA 4PDJA 3CLBA 4HOFA 1U72A 1DIUA 3SGYA 5JG0X 3F8YA 5JA3A 3I8AX 2W3AA 3ZPGA 1RX6A 3NZ6X 4EJ1A 2GD9A 2FZHA 3FL8A 5HT5A 2AZNA 1RA9A 3NZ9X 1RH3A 3JSUA 2L28A 2HM9A 3IA4A 2DHFA 3UM5A 4I1NA 4PSYA 3E0BA 5E8QA 4H95A 1RA8A 4OSGA 4FGHA 1KMSA 1KMVA 1PDBA 3NXOA 3F0QX 2P4GA 3SAIA 1RX4A
chains in the Genus database with same CATH superfamily
4DDRA 1DHIA 1DLRA 4P68A 1QZFA 4HA9A 4P66A 3IX9A 4HOGA 1AOEA 1OHKA 2HQPA 1MVTA 2BLBA 3IROA 3NZBX 4EILA 1AO8A 1DYHA 4ELBA 1RD7A 4ELFA 5HUIA 1E26A 1DR5A 4QHVA 3FRAX 3K74A 1RA3A 4KEBA 1HFPA 2W3BA 1RX3A 3GHVA 2FZIA 3INVA 3SR5X 4X5HA 2W3VA 3TQ8A 3SA2A 4IXFX 2CIGA 4EIZA 4KL9A 3FRDX 1DHFA 4PTHA 3K2HA 3QL0A 5DFRA 3M08A 4OR7A 1JOLA 5HVBA 1YHOA 3FQCA 1J3JA 3GHWA 5ECXA 3FYWX 4Q0DA 1D1GA 1MVSA 2KGKA 1RX8A 3KFYA 4XT6A 7DFRA 2LF1A 3NXTA 3S7AA 5U26A 3F0BX 2CD2A 3DL5A 3EX8A 2W9SA 1SEJA 1S3VA 4DPHA 3JVXA 4LAHX 3R33A 4QJZD 1DYIA 3CL9A 2BLCA 3JTWA 4DP3A 3GI2A 4X5FA 4QI9A 1M78A 3JWKA 1RX9A 2W3MA 4M6LA 2W9GA 1DR6A 4H96A 1U71A 1DR2A 2DRCA 1IA3A 1OHJA 2ANQA 1J3IA 3NXYA 3SA1A 3QFXA 4G3MA 4NX6A 2BLAA 4X5JA 1RA2A 4QLGA 1HFRA 4XT4A 3NXRA 3QG2A 1DG8A 3FQZA 4M6JA 1JUVA 4KNEA 2H2QA 2ITHA 2OBCA 4QLFA 3OAFA 5HVEA 1U70A 2O7PA 2JYBA 3F8ZA 3FL9A 4ECKA 4X5IA 1BOZA 1CD2A 3JWCA 3NXXA 1PD9A 1IA2A 3SRQX 4KAKA 4ELHA 2OIPA 3FQOA 3IA5A 3Q1HA 2G6VA 3CD2A 1DG7A 3HJ3A 1DDSA 3HBBA 1DG5A 2B3ZA 2D0KA 5HT4A 3EELA 3JWMA 3DGAA 1RX7A 3NTZA 3DATA 1DISA 3EEKA 1DRBA 1VJ3A 3SQYX 3IRNA 1DLSA 1DF7A 1M79A 2W3WA 2D5NA 3RO9A 4XECX 3LG4A 3F0VX 3FY8X 1DRHA 1DREA 4M6KA 4XRBA 2QK8A 4HOEA 3EEMA 4G8ZX 1PD8A 1S3WA 3JW5A 3N0HA 2C2SA 4M2XA 4P3RA 4M7UA 3QYLA 4FGGA 1JOMA 1DR1A 1DR3A 2ANOA 2FZJA 4KYAA 3K45A 1S3YA 4KLXA 3SRUX 4KJLA 3NRRA 3DRCA 3CSEA 1RB3A 3FQ0A 3EEJA 3GHCA 1LUDA 4XT8A 4KBNA 4KD7A 4HA7A 4KY8A 4ELGA 4GH8A 3FQVA 1RA1A 3FQFA 1BZFA 5ECCA 3F0UX 4IXED 5HF0X 4PTJA 3ROAA 3QGTA 1J3KA 2HXVA 3FY9X 3M09A 4DFRA 3NZAX 3DG8A 3K47A 4KJJA 5CCCA 3NZDA 8DFRA 4XT7A 4DPDA 3FREX 3SH2A 2W9HA 3NXVA 4LAGX 4XT5A 4NX7A 5FDAA 4X5GA 4KM2A 3SRRX 5CC9A 3L3RA 4H97A 3DFRA 4H98A 5U27A 4KFJA 4EIGA 3GYFA 3KGYA 5HSUA 3FRBX 3QLYA 3FS6A 4LEKX 3S9UA 3TQ9A 3DAUA 3TD8A 4QLEA 3QLRA 1RF7A 1S3UA 3JWFA 4QJCA 1DRFA 1DDRA 1DYRA 3QLSA 5HI6A 3IRMA 3VCOA 1RC4A 1RG7A 4G95A 4KJKA 4M7VA 3D84X 4PSTA 1RB2A 2INQA 4P3QA 3NZCX 3ZPCA 1AI9A 3QLZA 3RG9A 1KLKA 3F91A 3EIGA 5DXVA 1RE7A 3TQBA 4TU5X 5HQYA 6DFRA 1CZ3A 3KJRA 5HSRA 3QL3A 4LAEX 3FYVX 1ZDRA 1DR4A 1VDRA 3TQAA 2ZZAA 3KJSA 4KM0A 4ELEA 4I13A 3QYOA 2C2TA 4FHBA 3JW3A 3F0XX 4RGCA 5HF2X 4Q67A 2XW7A 3UM6A 3SRWX 3F0SX 3KY8A 5HPBA 5EAJA 3QLXA 3SRSX 1RX1A 1RX5A 1IA4A 2W9TA 1HFQA 4PSSA 1IA1A 4XE6X 3UM8A 1LY4A 1DR7A 4Q0EA 1DHJA 1DAJA 1RX2A 3S3VA 1M7AA 1DRAA 3D80A 2BL9A 1LY3A 4CD2A 1TDRA 1DYJA 3I3RA 3OCHA 4KY4A 3FRFX 4IXGX 3NU0A 3QLWA 3DL6A 4Q6AA 5HQZA 4PDJA 3CLBA 4HOFA 1U72A 1DIUA 3SGYA 5JG0X 3F8YA 5JA3A 3I8AX 2W3AA 3ZPGA 1RX6A 3NZ6X 4EJ1A 2GD9A 2FZHA 3FL8A 5HT5A 2AZNA 1RA9A 3NZ9X 1RH3A 3JSUA 2L28A 2HM9A 3IA4A 2DHFA 3UM5A 4I1NA 4PSYA 3E0BA 5E8QA 4H95A 1RA8A 4OSGA 4FGHA 1KMSA 1KMVA 1PDBA 3NXOA 3F0QX 2P4GA 3SAIA 1RX4A
chains in the Genus database with same CATH topology
4DDRA 1DHIA 1DLRA 4P68A 1QZFA 4HA9A 4P66A 3IX9A 4HOGA 1AOEA 1OHKA 2HQPA 1MVTA 2BLBA 3IROA 3NZBX 4EILA 1AO8A 1DYHA 4ELBA 1RD7A 4ELFA 5HUIA 1E26A 1DR5A 4QHVA 3FRAX 3K74A 1RA3A 4KEBA 1HFPA 2W3BA 1RX3A 3GHVA 2FZIA 3INVA 3SR5X 4X5HA 2W3VA 3TQ8A 3SA2A 4IXFX 2CIGA 4EIZA 4KL9A 3FRDX 1DHFA 4PTHA 3K2HA 3QL0A 5DFRA 3M08A 4OR7A 1JOLA 5HVBA 1YHOA 3FQCA 1J3JA 3GHWA 5ECXA 3FYWX 4Q0DA 1D1GA 1MVSA 2KGKA 1RX8A 3KFYA 4XT6A 7DFRA 2LF1A 3NXTA 3S7AA 5U26A 3F0BX 2CD2A 3DL5A 3EX8A 2W9SA 1SEJA 1S3VA 4DPHA 3JVXA 4LAHX 3R33A 4QJZD 1DYIA 3CL9A 2BLCA 3JTWA 4DP3A 3GI2A 4X5FA 4QI9A 1M78A 3JWKA 1RX9A 2W3MA 4M6LA 2W9GA 1DR6A 4H96A 1U71A 1DR2A 2DRCA 1IA3A 1OHJA 2ANQA 1J3IA 3NXYA 3SA1A 3QFXA 4G3MA 4NX6A 2BLAA 4X5JA 1RA2A 4QLGA 1HFRA 4XT4A 3NXRA 3QG2A 1DG8A 3FQZA 4M6JA 1JUVA 4KNEA 2H2QA 2ITHA 2OBCA 4QLFA 3OAFA 5HVEA 1U70A 2O7PA 2JYBA 3F8ZA 3FL9A 4ECKA 4X5IA 1BOZA 1CD2A 3JWCA 3NXXA 1PD9A 1IA2A 3SRQX 4KAKA 4ELHA 2OIPA 3FQOA 3IA5A 3Q1HA 2G6VA 3CD2A 1DG7A 3HJ3A 1DDSA 3HBBA 1DG5A 2B3ZA 2D0KA 5HT4A 3EELA 3JWMA 3DGAA 1RX7A 3NTZA 3DATA 1DISA 3EEKA 1DRBA 1VJ3A 3SQYX 3IRNA 1DLSA 1DF7A 1M79A 2W3WA 2D5NA 3RO9A 4XECX 3LG4A 3F0VX 3FY8X 1DRHA 1DREA 4M6KA 4XRBA 2QK8A 4HOEA 3EEMA 4G8ZX 1PD8A 1S3WA 3JW5A 3N0HA 2C2SA 4M2XA 4P3RA 4M7UA 3QYLA 4FGGA 1JOMA 1DR1A 1DR3A 2ANOA 2FZJA 4KYAA 3K45A 1S3YA 4KLXA 3SRUX 4KJLA 3NRRA 3DRCA 3CSEA 1RB3A 3FQ0A 3EEJA 3GHCA 1LUDA 4XT8A 4KBNA 4KD7A 4HA7A 4KY8A 4ELGA 4GH8A 3FQVA 1RA1A 3FQFA 1BZFA 5ECCA 3F0UX 4IXED 5HF0X 4PTJA 3ROAA 3QGTA 1J3KA 2HXVA 3FY9X 3M09A 4DFRA 3NZAX 3DG8A 3K47A 4KJJA 5CCCA 3NZDA 8DFRA 4XT7A 4DPDA 3FREX 3SH2A 2W9HA 3NXVA 4LAGX 4XT5A 4NX7A 5FDAA 4X5GA 4KM2A 3SRRX 5CC9A 3L3RA 4H97A 3DFRA 4H98A 5U27A 4KFJA 4EIGA 3GYFA 3KGYA 5HSUA 3FRBX 3QLYA 3FS6A 4LEKX 3S9UA 3TQ9A 3DAUA 3TD8A 4QLEA 3QLRA 1RF7A 1S3UA 3JWFA 4QJCA 1DRFA 1DDRA 1DYRA 3QLSA 5HI6A 3IRMA 3VCOA 1RC4A 1RG7A 4G95A 4KJKA 4M7VA 3D84X 4PSTA 1RB2A 2INQA 4P3QA 3NZCX 3ZPCA 1AI9A 3QLZA 3RG9A 1KLKA 3F91A 3EIGA 5DXVA 1RE7A 3TQBA 4TU5X 5HQYA 6DFRA 1CZ3A 3KJRA 5HSRA 3QL3A 4LAEX 3FYVX 1ZDRA 1DR4A 1VDRA 3TQAA 2ZZAA 3KJSA 4KM0A 4ELEA 4I13A 3QYOA 2C2TA 4FHBA 3JW3A 3F0XX 4RGCA 5HF2X 4Q67A 2XW7A 3UM6A 3SRWX 3F0SX 3KY8A 5HPBA 5EAJA 3QLXA 3SRSX 1RX1A 1RX5A 1IA4A 2W9TA 1HFQA 4PSSA 1IA1A 4XE6X 3UM8A 1LY4A 1DR7A 4Q0EA 1DHJA 1DAJA 1RX2A 3S3VA 1M7AA 1DRAA 3D80A 2BL9A 1LY3A 4CD2A 1TDRA 1DYJA 3I3RA 3OCHA 4KY4A 3FRFX 4IXGX 3NU0A 3QLWA 3DL6A 4Q6AA 5HQZA 4PDJA 3CLBA 4HOFA 1U72A 1DIUA 3SGYA 5JG0X 3F8YA 5JA3A 3I8AX 2W3AA 3ZPGA 1RX6A 3NZ6X 4EJ1A 2GD9A 2FZHA 3FL8A 5HT5A 2AZNA 1RA9A 3NZ9X 1RH3A 3JSUA 2L28A 2HM9A 3IA4A 2DHFA 3UM5A 4I1NA 4PSYA 3E0BA 5E8QA 4H95A 1RA8A 4OSGA 4FGHA 1KMSA 1KMVA 1PDBA 3NXOA 3F0QX 2P4GA 3SAIA 1RX4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DDR A;  1DHI A;  1DLR A;  4P68 A;  1QZF A;  4HA9 A;  4P66 A;  3IX9 A;  4HOG A;  1AOE A;  1OHK A;  2HQP A;  1MVT A;  2BLB A;  3IRO A;  3NZB X;  4EIL A;  1AO8 A;  1DYH A;  4ELB A;  1RD7 A;  4ELF A;  5HUI A;  1E26 A;  1DR5 A;  4QHV A;  3FRA X;  3K74 A;  1RA3 A;  4KEB A;  1HFP A;  2W3B A;  1RX3 A;  3GHV A;  2FZI A;  3INV A;  3SR5 X;  4X5H A;  2W3V A;  3TQ8 A;  3SA2 A;  4IXF X;  2CIG A;  4EIZ A;  4KL9 A;  3FRD X;  1DHF A;  4PTH A;  3K2H A;  3QL0 A;  5DFR A;  3M08 A;  4OR7 A;  1JOL A;  5HVB A;  1YHO A;  3FQC A;  1J3J A;  3GHW A;  5ECX A;  3FYW X;  4Q0D A;  1D1G A;  1MVS A;  2KGK A;  1RX8 A;  3KFY A;  4XT6 A;  7DFR A;  2LF1 A;  3NXT A;  3S7A A;  5U26 A;  3F0B X;  2CD2 A;  3DL5 A;  3EX8 A;  2W9S A;  1SEJ A;  1S3V A;  4DPH A;  3JVX A;  4LAH X;  3R33 A;  4QJZ D;  1DYI A;  3CL9 A;  2BLC A;  3JTW A;  4DP3 A;  3GI2 A;  4X5F A;  4QI9 A;  1M78 A;  3JWK A;  1RX9 A;  2W3M A;  4M6L A;  2W9G A;  1DR6 A;  4H96 A;  1U71 A;  1DR2 A;  2DRC A;  1IA3 A;  1OHJ A;  2ANQ A;  1J3I A;  3NXY A;  3SA1 A;  3QFX A;  4G3M A;  4NX6 A;  2BLA A;  4X5J A;  1RA2 A;  4QLG A;  1HFR A;  4XT4 A;  3NXR A;  3QG2 A;  1DG8 A;  3FQZ A;  4M6J A;  1JUV A;  4KNE A;  2H2Q A;  2ITH A;  2OBC A;  4QLF A;  3OAF A;  5HVE A;  1U70 A;  2O7P A;  2JYB A;  3F8Z A;  3FL9 A;  4ECK A;  4X5I A;  1BOZ A;  1CD2 A;  3JWC A;  3NXX A;  1PD9 A;  1IA2 A;  3SRQ X;  4KAK A;  4ELH A;  2OIP A;  3FQO A;  3IA5 A;  3Q1H A;  2G6V A;  3CD2 A;  1DG7 A;  3HJ3 A;  1DDS A;  3HBB A;  1DG5 A;  2B3Z A;  2D0K A;  5HT4 A;  3EEL A;  3JWM A;  3DGA A;  1RX7 A;  3NTZ A;  3DAT A;  1DIS A;  3EEK A;  1DRB A;  1VJ3 A;  3SQY X;  3IRN A;  1DLS A;  1DF7 A;  1M79 A;  2W3W A;  2D5N A;  3RO9 A;  4XEC X;  3LG4 A;  3F0V X;  3FY8 X;  1DRH A;  1DRE A;  4M6K A;  4XRB A;  2QK8 A;  4HOE A;  3EEM A;  4G8Z X;  1PD8 A;  1S3W A;  3JW5 A;  3N0H A;  2C2S A;  4M2X A;  4P3R A;  4M7U A;  3QYL A;  4FGG A;  1JOM A;  1DR1 A;  1DR3 A;  2ANO A;  2FZJ A;  4KYA A;  3K45 A;  1S3Y A;  4KLX A;  3SRU X;  4KJL A;  3NRR A;  3DRC A;  3CSE A;  1RB3 A;  3FQ0 A;  3EEJ A;  3GHC A;  1LUD A;  4XT8 A;  4KBN A;  4KD7 A;  4HA7 A;  4KY8 A;  4ELG A;  4GH8 A;  3FQV A;  1RA1 A;  3FQF A;  1BZF A;  5ECC A;  3F0U X;  4IXE D;  5HF0 X;  4PTJ A;  3ROA A;  3QGT A;  1J3K A;  2HXV A;  3FY9 X;  3M09 A;  4DFR A;  3NZA X;  3DG8 A;  3K47 A;  4KJJ A;  5CCC A;  3NZD A;  8DFR A;  4XT7 A;  4DPD A;  3FRE X;  3SH2 A;  2W9H A;  3NXV A;  4LAG X;  4XT5 A;  4NX7 A;  5FDA A;  4X5G A;  4KM2 A;  3SRR X;  5CC9 A;  3L3R A;  4H97 A;  3DFR A;  4H98 A;  5U27 A;  4KFJ A;  4EIG A;  3GYF A;  3KGY A;  5HSU A;  3FRB X;  3QLY A;  3FS6 A;  4LEK X;  3S9U A;  3TQ9 A;  3DAU A;  3TD8 A;  4QLE A;  3QLR A;  1RF7 A;  1S3U A;  3JWF A;  4QJC A;  1DRF A;  1DDR A;  1DYR A;  3QLS A;  5HI6 A;  3IRM A;  3VCO A;  1RC4 A;  1RG7 A;  4G95 A;  4KJK A;  4M7V A;  3D84 X;  4PST A;  1RB2 A;  2INQ A;  4P3Q A;  3NZC X;  3ZPC A;  1AI9 A;  3QLZ A;  3RG9 A;  1KLK A;  3F91 A;  3EIG A;  5DXV A;  1RE7 A;  3TQB A;  4TU5 X;  5HQY A;  6DFR A;  1CZ3 A;  3KJR A;  5HSR A;  3QL3 A;  4LAE X;  3FYV X;  1ZDR A;  1DR4 A;  1VDR A;  3TQA A;  2ZZA A;  3KJS A;  4KM0 A;  4ELE A;  4I13 A;  3QYO A;  2C2T A;  4FHB A;  3JW3 A;  3F0X X;  4RGC A;  5HF2 X;  4Q67 A;  2XW7 A;  3UM6 A;  3SRW X;  3F0S X;  3KY8 A;  5HPB A;  5EAJ A;  3QLX A;  3SRS X;  1RX1 A;  1RX5 A;  1IA4 A;  2W9T A;  1HFQ A;  4PSS A;  1IA1 A;  4XE6 X;  3UM8 A;  1LY4 A;  1DR7 A;  4Q0E A;  1DHJ A;  1DAJ A;  1RX2 A;  3S3V A;  1M7A A;  1DRA A;  3D80 A;  2BL9 A;  1LY3 A;  4CD2 A;  1TDR A;  1DYJ A;  3I3R A;  3OCH A;  4KY4 A;  3FRF X;  4IXG X;  3NU0 A;  3QLW A;  3DL6 A;  4Q6A A;  5HQZ A;  4PDJ A;  3CLB A;  4HOF A;  1U72 A;  1DIU A;  3SGY A;  5JG0 X;  3F8Y A;  5JA3 A;  3I8A X;  2W3A A;  3ZPG A;  1RX6 A;  3NZ6 X;  4EJ1 A;  2GD9 A;  2FZH A;  3FL8 A;  5HT5 A;  2AZN A;  1RA9 A;  3NZ9 X;  1RH3 A;  3JSU A;  2L28 A;  2HM9 A;  3IA4 A;  2DHF A;  3UM5 A;  4I1N A;  4PSY A;  3E0B A;  5E8Q A;  4H95 A;  1RA8 A;  4OSG A;  4FGH A;  1KMS A;  1KMV A;  1PDB A;  3NXO A;  3F0Q X;  2P4G A;  3SAI A;  1RX4 A; 
#chains in the Genus database with same CATH topology
 4DDR A;  1DHI A;  1DLR A;  4P68 A;  1QZF A;  4HA9 A;  4P66 A;  3IX9 A;  4HOG A;  1AOE A;  1OHK A;  2HQP A;  1MVT A;  2BLB A;  3IRO A;  3NZB X;  4EIL A;  1AO8 A;  1DYH A;  4ELB A;  1RD7 A;  4ELF A;  5HUI A;  1E26 A;  1DR5 A;  4QHV A;  3FRA X;  3K74 A;  1RA3 A;  4KEB A;  1HFP A;  2W3B A;  1RX3 A;  3GHV A;  2FZI A;  3INV A;  3SR5 X;  4X5H A;  2W3V A;  3TQ8 A;  3SA2 A;  4IXF X;  2CIG A;  4EIZ A;  4KL9 A;  3FRD X;  1DHF A;  4PTH A;  3K2H A;  3QL0 A;  5DFR A;  3M08 A;  4OR7 A;  1JOL A;  5HVB A;  1YHO A;  3FQC A;  1J3J A;  3GHW A;  5ECX A;  3FYW X;  4Q0D A;  1D1G A;  1MVS A;  2KGK A;  1RX8 A;  3KFY A;  4XT6 A;  7DFR A;  2LF1 A;  3NXT A;  3S7A A;  5U26 A;  3F0B X;  2CD2 A;  3DL5 A;  3EX8 A;  2W9S A;  1SEJ A;  1S3V A;  4DPH A;  3JVX A;  4LAH X;  3R33 A;  4QJZ D;  1DYI A;  3CL9 A;  2BLC A;  3JTW A;  4DP3 A;  3GI2 A;  4X5F A;  4QI9 A;  1M78 A;  3JWK A;  1RX9 A;  2W3M A;  4M6L A;  2W9G A;  1DR6 A;  4H96 A;  1U71 A;  1DR2 A;  2DRC A;  1IA3 A;  1OHJ A;  2ANQ A;  1J3I A;  3NXY A;  3SA1 A;  3QFX A;  4G3M A;  4NX6 A;  2BLA A;  4X5J A;  1RA2 A;  4QLG A;  1HFR A;  4XT4 A;  3NXR A;  3QG2 A;  1DG8 A;  3FQZ A;  4M6J A;  1JUV A;  4KNE A;  2H2Q A;  2ITH A;  2OBC A;  4QLF A;  3OAF A;  5HVE A;  1U70 A;  2O7P A;  2JYB A;  3F8Z A;  3FL9 A;  4ECK A;  4X5I A;  1BOZ A;  1CD2 A;  3JWC A;  3NXX A;  1PD9 A;  1IA2 A;  3SRQ X;  4KAK A;  4ELH A;  2OIP A;  3FQO A;  3IA5 A;  3Q1H A;  2G6V A;  3CD2 A;  1DG7 A;  3HJ3 A;  1DDS A;  3HBB A;  1DG5 A;  2B3Z A;  2D0K A;  5HT4 A;  3EEL A;  3JWM A;  3DGA A;  1RX7 A;  3NTZ A;  3DAT A;  1DIS A;  3EEK A;  1DRB A;  1VJ3 A;  3SQY X;  3IRN A;  1DLS A;  1DF7 A;  1M79 A;  2W3W A;  2D5N A;  3RO9 A;  4XEC X;  3LG4 A;  3F0V X;  3FY8 X;  1DRH A;  1DRE A;  4M6K A;  4XRB A;  2QK8 A;  4HOE A;  3EEM A;  4G8Z X;  1PD8 A;  1S3W A;  3JW5 A;  3N0H A;  2C2S A;  4M2X A;  4P3R A;  4M7U A;  3QYL A;  4FGG A;  1JOM A;  1DR1 A;  1DR3 A;  2ANO A;  2FZJ A;  4KYA A;  3K45 A;  1S3Y A;  4KLX A;  3SRU X;  4KJL A;  3NRR A;  3DRC A;  3CSE A;  1RB3 A;  3FQ0 A;  3EEJ A;  3GHC A;  1LUD A;  4XT8 A;  4KBN A;  4KD7 A;  4HA7 A;  4KY8 A;  4ELG A;  4GH8 A;  3FQV A;  1RA1 A;  3FQF A;  1BZF A;  5ECC A;  3F0U X;  4IXE D;  5HF0 X;  4PTJ A;  3ROA A;  3QGT A;  1J3K A;  2HXV A;  3FY9 X;  3M09 A;  4DFR A;  3NZA X;  3DG8 A;  3K47 A;  4KJJ A;  5CCC A;  3NZD A;  8DFR A;  4XT7 A;  4DPD A;  3FRE X;  3SH2 A;  2W9H A;  3NXV A;  4LAG X;  4XT5 A;  4NX7 A;  5FDA A;  4X5G A;  4KM2 A;  3SRR X;  5CC9 A;  3L3R A;  4H97 A;  3DFR A;  4H98 A;  5U27 A;  4KFJ A;  4EIG A;  3GYF A;  3KGY A;  5HSU A;  3FRB X;  3QLY A;  3FS6 A;  4LEK X;  3S9U A;  3TQ9 A;  3DAU A;  3TD8 A;  4QLE A;  3QLR A;  1RF7 A;  1S3U A;  3JWF A;  4QJC A;  1DRF A;  1DDR A;  1DYR A;  3QLS A;  5HI6 A;  3IRM A;  3VCO A;  1RC4 A;  1RG7 A;  4G95 A;  4KJK A;  4M7V A;  3D84 X;  4PST A;  1RB2 A;  2INQ A;  4P3Q A;  3NZC X;  3ZPC A;  1AI9 A;  3QLZ A;  3RG9 A;  1KLK A;  3F91 A;  3EIG A;  5DXV A;  1RE7 A;  3TQB A;  4TU5 X;  5HQY A;  6DFR A;  1CZ3 A;  3KJR A;  5HSR A;  3QL3 A;  4LAE X;  3FYV X;  1ZDR A;  1DR4 A;  1VDR A;  3TQA A;  2ZZA A;  3KJS A;  4KM0 A;  4ELE A;  4I13 A;  3QYO A;  2C2T A;  4FHB A;  3JW3 A;  3F0X X;  4RGC A;  5HF2 X;  4Q67 A;  2XW7 A;  3UM6 A;  3SRW X;  3F0S X;  3KY8 A;  5HPB A;  5EAJ A;  3QLX A;  3SRS X;  1RX1 A;  1RX5 A;  1IA4 A;  2W9T A;  1HFQ A;  4PSS A;  1IA1 A;  4XE6 X;  3UM8 A;  1LY4 A;  1DR7 A;  4Q0E A;  1DHJ A;  1DAJ A;  1RX2 A;  3S3V A;  1M7A A;  1DRA A;  3D80 A;  2BL9 A;  1LY3 A;  4CD2 A;  1TDR A;  1DYJ A;  3I3R A;  3OCH A;  4KY4 A;  3FRF X;  4IXG X;  3NU0 A;  3QLW A;  3DL6 A;  4Q6A A;  5HQZ A;  4PDJ A;  3CLB A;  4HOF A;  1U72 A;  1DIU A;  3SGY A;  5JG0 X;  3F8Y A;  5JA3 A;  3I8A X;  2W3A A;  3ZPG A;  1RX6 A;  3NZ6 X;  4EJ1 A;  2GD9 A;  2FZH A;  3FL8 A;  5HT5 A;  2AZN A;  1RA9 A;  3NZ9 X;  1RH3 A;  3JSU A;  2L28 A;  2HM9 A;  3IA4 A;  2DHF A;  3UM5 A;  4I1N A;  4PSY A;  3E0B A;  5E8Q A;  4H95 A;  1RA8 A;  4OSG A;  4FGH A;  1KMS A;  1KMV A;  1PDB A;  3NXO A;  3F0Q X;  2P4G A;  3SAI A;  1RX4 A; 
#chains in the Genus database with same CATH homology
 4DDR A;  1DHI A;  1DLR A;  4P68 A;  1QZF A;  4HA9 A;  4P66 A;  3IX9 A;  4HOG A;  1AOE A;  1OHK A;  2HQP A;  1MVT A;  2BLB A;  3IRO A;  3NZB X;  4EIL A;  1AO8 A;  1DYH A;  4ELB A;  1RD7 A;  4ELF A;  5HUI A;  1E26 A;  1DR5 A;  4QHV A;  3FRA X;  3K74 A;  1RA3 A;  4KEB A;  1HFP A;  2W3B A;  1RX3 A;  3GHV A;  2FZI A;  3INV A;  3SR5 X;  4X5H A;  2W3V A;  3TQ8 A;  3SA2 A;  4IXF X;  2CIG A;  4EIZ A;  4KL9 A;  3FRD X;  1DHF A;  4PTH A;  3K2H A;  3QL0 A;  5DFR A;  3M08 A;  4OR7 A;  1JOL A;  5HVB A;  1YHO A;  3FQC A;  1J3J A;  3GHW A;  5ECX A;  3FYW X;  4Q0D A;  1D1G A;  1MVS A;  2KGK A;  1RX8 A;  3KFY A;  4XT6 A;  7DFR A;  2LF1 A;  3NXT A;  3S7A A;  5U26 A;  3F0B X;  2CD2 A;  3DL5 A;  3EX8 A;  2W9S A;  1SEJ A;  1S3V A;  4DPH A;  3JVX A;  4LAH X;  3R33 A;  4QJZ D;  1DYI A;  3CL9 A;  2BLC A;  3JTW A;  4DP3 A;  3GI2 A;  4X5F A;  4QI9 A;  1M78 A;  3JWK A;  1RX9 A;  2W3M A;  4M6L A;  2W9G A;  1DR6 A;  4H96 A;  1U71 A;  1DR2 A;  2DRC A;  1IA3 A;  1OHJ A;  2ANQ A;  1J3I A;  3NXY A;  3SA1 A;  3QFX A;  4G3M A;  4NX6 A;  2BLA A;  4X5J A;  1RA2 A;  4QLG A;  1HFR A;  4XT4 A;  3NXR A;  3QG2 A;  1DG8 A;  3FQZ A;  4M6J A;  1JUV A;  4KNE A;  2H2Q A;  2ITH A;  2OBC A;  4QLF A;  3OAF A;  5HVE A;  1U70 A;  2O7P A;  2JYB A;  3F8Z A;  3FL9 A;  4ECK A;  4X5I A;  1BOZ A;  1CD2 A;  3JWC A;  3NXX A;  1PD9 A;  1IA2 A;  3SRQ X;  4KAK A;  4ELH A;  2OIP A;  3FQO A;  3IA5 A;  3Q1H A;  2G6V A;  3CD2 A;  1DG7 A;  3HJ3 A;  1DDS A;  3HBB A;  1DG5 A;  2B3Z A;  2D0K A;  5HT4 A;  3EEL A;  3JWM A;  3DGA A;  1RX7 A;  3NTZ A;  3DAT A;  1DIS A;  3EEK A;  1DRB A;  1VJ3 A;  3SQY X;  3IRN A;  1DLS A;  1DF7 A;  1M79 A;  2W3W A;  2D5N A;  3RO9 A;  4XEC X;  3LG4 A;  3F0V X;  3FY8 X;  1DRH A;  1DRE A;  4M6K A;  4XRB A;  2QK8 A;  4HOE A;  3EEM A;  4G8Z X;  1PD8 A;  1S3W A;  3JW5 A;  3N0H A;  2C2S A;  4M2X A;  4P3R A;  4M7U A;  3QYL A;  4FGG A;  1JOM A;  1DR1 A;  1DR3 A;  2ANO A;  2FZJ A;  4KYA A;  3K45 A;  1S3Y A;  4KLX A;  3SRU X;  4KJL A;  3NRR A;  3DRC A;  3CSE A;  1RB3 A;  3FQ0 A;  3EEJ A;  3GHC A;  1LUD A;  4XT8 A;  4KBN A;  4KD7 A;  4HA7 A;  4KY8 A;  4ELG A;  4GH8 A;  3FQV A;  1RA1 A;  3FQF A;  1BZF A;  5ECC A;  3F0U X;  4IXE D;  5HF0 X;  4PTJ A;  3ROA A;  3QGT A;  1J3K A;  2HXV A;  3FY9 X;  3M09 A;  4DFR A;  3NZA X;  3DG8 A;  3K47 A;  4KJJ A;  5CCC A;  3NZD A;  8DFR A;  4XT7 A;  4DPD A;  3FRE X;  3SH2 A;  2W9H A;  3NXV A;  4LAG X;  4XT5 A;  4NX7 A;  5FDA A;  4X5G A;  4KM2 A;  3SRR X;  5CC9 A;  3L3R A;  4H97 A;  3DFR A;  4H98 A;  5U27 A;  4KFJ A;  4EIG A;  3GYF A;  3KGY A;  5HSU A;  3FRB X;  3QLY A;  3FS6 A;  4LEK X;  3S9U A;  3TQ9 A;  3DAU A;  3TD8 A;  4QLE A;  3QLR A;  1RF7 A;  1S3U A;  3JWF A;  4QJC A;  1DRF A;  1DDR A;  1DYR A;  3QLS A;  5HI6 A;  3IRM A;  3VCO A;  1RC4 A;  1RG7 A;  4G95 A;  4KJK A;  4M7V A;  3D84 X;  4PST A;  1RB2 A;  2INQ A;  4P3Q A;  3NZC X;  3ZPC A;  1AI9 A;  3QLZ A;  3RG9 A;  1KLK A;  3F91 A;  3EIG A;  5DXV A;  1RE7 A;  3TQB A;  4TU5 X;  5HQY A;  6DFR A;  1CZ3 A;  3KJR A;  5HSR A;  3QL3 A;  4LAE X;  3FYV X;  1ZDR A;  1DR4 A;  1VDR A;  3TQA A;  2ZZA A;  3KJS A;  4KM0 A;  4ELE A;  4I13 A;  3QYO A;  2C2T A;  4FHB A;  3JW3 A;  3F0X X;  4RGC A;  5HF2 X;  4Q67 A;  2XW7 A;  3UM6 A;  3SRW X;  3F0S X;  3KY8 A;  5HPB A;  5EAJ A;  3QLX A;  3SRS X;  1RX1 A;  1RX5 A;  1IA4 A;  2W9T A;  1HFQ A;  4PSS A;  1IA1 A;  4XE6 X;  3UM8 A;  1LY4 A;  1DR7 A;  4Q0E A;  1DHJ A;  1DAJ A;  1RX2 A;  3S3V A;  1M7A A;  1DRA A;  3D80 A;  2BL9 A;  1LY3 A;  4CD2 A;  1TDR A;  1DYJ A;  3I3R A;  3OCH A;  4KY4 A;  3FRF X;  4IXG X;  3NU0 A;  3QLW A;  3DL6 A;  4Q6A A;  5HQZ A;  4PDJ A;  3CLB A;  4HOF A;  1U72 A;  1DIU A;  3SGY A;  5JG0 X;  3F8Y A;  5JA3 A;  3I8A X;  2W3A A;  3ZPG A;  1RX6 A;  3NZ6 X;  4EJ1 A;  2GD9 A;  2FZH A;  3FL8 A;  5HT5 A;  2AZN A;  1RA9 A;  3NZ9 X;  1RH3 A;  3JSU A;  2L28 A;  2HM9 A;  3IA4 A;  2DHF A;  3UM5 A;  4I1N A;  4PSY A;  3E0B A;  5E8Q A;  4H95 A;  1RA8 A;  4OSG A;  4FGH A;  1KMS A;  1KMV A;  1PDB A;  3NXO A;  3F0Q X;  2P4G A;  3SAI A;  1RX4 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...