4DKYA

Crystal structure analysis of n terminal region containing the dimerization domain and dna binding domain of hu protein(histone like protein-dna binding) from mycobacterium tuberculosis [h37rv]
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
97
structure length
97
Chain Sequence
MNKAELIDVLTQKLGSDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRAARVARNPRTGETVKVKPTSVPAFRPGAQFKAVVSGAQRLPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors
pubmed doi rcsb
molecule tags Dna binding protein
source organism Mycobacterium tuberculosis
molecule keywords DNA-binding protein HU homolog
total genus 23
structure length 97
sequence length 97
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00216 Bac_DNA_binding Bacterial DNA-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.520.10 Few Secondary Structures Irregular HU Protein; Chain A IHF-like DNA-binding proteins 4dkyA00
1WTUA 1OWGA 4YFTC 3RHIA 5FBMA 1P78A 1HUUA 1OUZB 4P3VA 1HUEA 5L8ZA 4YEWC 1B8ZA 2O97B 4YFTA 2NP2A 4YFHA 1RIYA 1IHFA 1OWFA 1MULA 4YEWA 2HT0A 2IIEA 1EXEA 4QJNA 1OWGB 2NDPA 4DKYA 4PT4A 4YEYA 4YEXA 1OUZA 2O97A 4FMRA 4YF0A 1P71A 1IHFB 1P51A 1OWFB 2HT0B 2IIFA 4N1VA 5EKAA 4QJUA
chains in the Genus database with same CATH superfamily
1WTUA 1OWGA 4YFTC 3RHIA 5FBMA 1P78A 1HUUA 1OUZB 4P3VA 1HUEA 5L8ZA 4YEWC 1B8ZA 2O97B 4YFTA 2NP2A 4YFHA 1RIYA 1IHFA 1OWFA 1MULA 4YEWA 2HT0A 2IIEA 1EXEA 4QJNA 1OWGB 2NDPA 4DKYA 4PT4A 4YEYA 4YEXA 1OUZA 2O97A 4FMRA 4YF0A 1P71A 1IHFB 1P51A 1OWFB 2HT0B 2IIFA 4N1VA 5EKAA 4QJUA
chains in the Genus database with same CATH topology
1WTUA 1OWGA 4YFTC 3RHIA 5FBMA 1P78A 1HUUA 1OUZB 4P3VA 1HUEA 5L8ZA 4YEWC 1B8ZA 2O97B 4YFTA 2NP2A 4YFHA 1RIYA 1IHFA 1OWFA 1MULA 4YEWA 2HT0A 2IIEA 1EXEA 4QJNA 1OWGB 2NDPA 4DKYA 4PT4A 4YEYA 4YEXA 1OUZA 2O97A 4FMRA 4YF0A 1P71A 1IHFB 1P51A 1OWFB 2HT0B 2IIFA 4N1VA 5EKAA 4QJUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WTU A;  1OWG A;  4YFT C;  3RHI A;  5FBM A;  1P78 A;  1HUU A;  1OUZ B;  4P3V A;  1HUE A;  5L8Z A;  4YEW C;  1B8Z A;  2O97 B;  4YFT A;  2NP2 A;  4YFH A;  1RIY A;  1IHF A;  1OWF A;  1MUL A;  4YEW A;  2HT0 A;  2IIE A;  1EXE A;  4QJN A;  1OWG B;  2NDP A;  4DKY A;  4PT4 A;  4YEY A;  4YEX A;  1OUZ A;  2O97 A;  4FMR A;  4YF0 A;  1P71 A;  1IHF B;  1P51 A;  1OWF B;  2HT0 B;  2IIF A;  4N1V A;  5EKA A;  4QJU A; 
#chains in the Genus database with same CATH topology
 1WTU A;  1OWG A;  4YFT C;  3RHI A;  5FBM A;  1P78 A;  1HUU A;  1OUZ B;  4P3V A;  1HUE A;  5L8Z A;  4YEW C;  1B8Z A;  2O97 B;  4YFT A;  2NP2 A;  4YFH A;  1RIY A;  1IHF A;  1OWF A;  1MUL A;  4YEW A;  2HT0 A;  2IIE A;  1EXE A;  4QJN A;  1OWG B;  2NDP A;  4DKY A;  4PT4 A;  4YEY A;  4YEX A;  1OUZ A;  2O97 A;  4FMR A;  4YF0 A;  1P71 A;  1IHF B;  1P51 A;  1OWF B;  2HT0 B;  2IIF A;  4N1V A;  5EKA A;  4QJU A; 
#chains in the Genus database with same CATH homology
 1WTU A;  1OWG A;  4YFT C;  3RHI A;  5FBM A;  1P78 A;  1HUU A;  1OUZ B;  4P3V A;  1HUE A;  5L8Z A;  4YEW C;  1B8Z A;  2O97 B;  4YFT A;  2NP2 A;  4YFH A;  1RIY A;  1IHF A;  1OWF A;  1MUL A;  4YEW A;  2HT0 A;  2IIE A;  1EXE A;  4QJN A;  1OWG B;  2NDP A;  4DKY A;  4PT4 A;  4YEY A;  4YEX A;  1OUZ A;  2O97 A;  4FMR A;  4YF0 A;  1P71 A;  1IHF B;  1P51 A;  1OWF B;  2HT0 B;  2IIF A;  4N1V A;  5EKA A;  4QJU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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