4DLCA

Crystal structure of trypanosoma brucei dutpase with dump, mgf3- transition state analogue, and mg2+
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
280
structure length
222
Chain Sequence
VSLSPLILRSLAELQDGLNTVVDKNWRQLRRPGDWSLAITMEAAELLDSYPWKWWKNVKAQPDLQNVKIELTDILHFSLSGAMQVSDELADFMFFPLSDTNNALASFQNIIRLASLQRFQLVTSAVIAAADDIGFNLVAYYVAKHTLNGIRQMKGYKDGTYVKVQKGVEDNELLHGCISPFSLDDVTNEGNYKTKWDDIMHRVYDAFGTPKEERLNIGHWLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Deoxyuridine triphosphatase
publication title On the catalytic mechanism of dimeric dUTPases.
pubmed doi rcsb
source organism Trypanosoma brucei
total genus 90
structure length 222
sequence length 280
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2012-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08761 dUTPase_2 dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.4010.10 Mainly Alpha Orthogonal Bundle all-alpha NTP pyrophosphatase fold Type II deoxyuridine triphosphatase 4dlcA00
1W2YA 2CICA 4DL8A 4DK4A 4DLCA 4DKBA
chains in the Genus database with same CATH superfamily
1W2YA 2CICA 4DL8A 4DK4A 4DLCA 4DKBA
chains in the Genus database with same CATH topology
1W2YA 2CICA 2CJEA 2YAZA 4DL8A 4DK2A 2YAYA 1OGKA 1OGLA 2YB0A 4DK4A 4DLCA 4DKBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W2Y A;  2CIC A;  4DL8 A;  4DK4 A;  4DLC A;  4DKB A; 
#chains in the Genus database with same CATH topology
 1W2Y A;  2CIC A;  4DL8 A;  4DK4 A;  4DLC A;  4DKB A; 
#chains in the Genus database with same CATH homology
 1W2Y A;  2CIC A;  2CJE A;  2YAZ A;  4DL8 A;  4DK2 A;  2YAY A;  1OGK A;  1OGL A;  2YB0 A;  4DK4 A;  4DLC A;  4DKB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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