The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
13
|
sequence length |
60
|
structure length |
60
|
Chain Sequence |
EKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGH
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Hemostatic effect of a monoclonal antibody mAb 2021 blocking the interaction between FXa and TFPI in a rabbit hemophilia model.
pubmed doi rcsb |
| molecule tags |
Blood clotting inhibitor/immune system
|
| source organism |
Homo sapiens
|
| molecule keywords |
Humanized recombinant FAB fragment, FAB 2021, of a murine an
|
| total genus |
13
|
| structure length |
60
|
| sequence length |
60
|
| ec nomenclature | |
| pdb deposition date | 2012-02-21 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| K | PF00014 | Kunitz_BPTI | Kunitz/Bovine pancreatic trypsin inhibitor domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Few Secondary Structures | Irregular | Factor Xa Inhibitor | Pancreatic trypsin inhibitor Kunitz domain |
#chains in the Genus database with same CATH superfamily 1TAW B; 1NAG A; 1CA0 D; 4Y0Z I; 3TGI I; 1T8O B; 3BTG I; 1BHC A; 1KIG I; 1ZJD B; 1LD6 A; 3L3T E; 1KTH A; 2TGP I; 3U1J E; 1BRC I; 1MTN D; 3AUI A; 1DTK A; 3BTT I; 2HEX A; 3LDJ A; 1TFX C; 1BZ5 A; 1YKT B; 2UUX A; 2FI4 I; 2UUY B; 3AUD A; 3UIR C; 5JB7 A; 4BNR I; 1JV9 A; 2JOT A; 4PTI A; 1TOC R; 1K6U A; 1ZR0 B; 1BIK A; 2DDJ A; 1YLD B; 1P2O B; 1UUB A; 3AUE A; 1DTX A; 4TPI I; 7PTI A; 2W8X A; 5JB6 A; 1F7Z I; 3BTD I; 1SHP A; 2LFK A; 1IRH A; 1JV8 A; 1TAP A; 2KCR A; 1F5R I; 1P2Q B; 2ODY E; 2KAI I; 4U30 W; 4NTY B; 8PTI A; 1P2K I; 2LFL A; 3BYB A; 3FP8 I; 4WWY C; 4Y11 I; 1DEN A; 4ISN B; 1BRB I; 9PTI A; 3BTE I; 2IJO I; 1QLQ A; 3LDM A; 1BPI A; 1LD5 A; 4WXV C; 3M7Q B; 1FAN A; 3FP6 I; 2PTC I; 2RA3 C; 4BQD A; 3AUG A; 2ZJX A; 1T8N B; 3OTJ I; 4BD9 B; 3L33 E; 3BTW I; 3TGJ I; 1P2N B; 1YLC B; 1UUA A; 4Y10 I; 3TGK I; 2KNT A; 4ISL B; 5JB5 A; 2ZVX A; 2CA7 A; 1B0C A; 3BTH I; 2FI5 I; 2DDI A; 5PTI A; 1P2M B; 1ADZ A; 3LDI A; 3P92 E; 1TCP A; 3D65 I; 4ISO B; 3UOU B; 1BZX I; 1BTI A; 3TPI I; 3BTM I; 3FP7 J; 4NTX B; 3BTF I; 1KUN A; 6PTI A; 4DG4 C; 4NTW B; 5JB4 A; 1T8M B; 1TPA I; 2FTL I; 4Y0Y I; 3BTK I; 1OA5 5; 1KNT A; 1Y62 A; 3T62 D; 1BF0 A; 1D0D A; 1CO7 I; 1P2I I; 4U32 X; 2R9P E; 1OA6 5; 3WNY A; 1DEM A; 1D0D B; 2M99 A; 1AAP A; 1BUN B; 1EAW B; 3BTQ I; 1BPT A; 1FAK I; 3AUB A; 3AUH A; 1G6X A; 3P95 E; 1T8L B; 2TPI I; 3AUC A; 2FI3 I; 5C67 C; 1T7C B; 2M01 A; 3GYM I; 1EJM B; 2FTM B; 1AAL A; 1BTH P; 1FY8 I; 1P2J I; 2J6D A; 3CI7 A; 1CBW D; 4DTG K; 1JC6 A; 3OFW A; 1YC0 I; 1PIT A; #chains in the Genus database with same CATH topology 1TAW B; 1NAG A; 1CA0 D; 4Y0Z I; 3TGI I; 1T8O B; 3BTG I; 1BHC A; 1KIG I; 1ZJD B; 1LD6 A; 3L3T E; 1KTH A; 2TGP I; 3U1J E; 1BRC I; 1MTN D; 3AUI A; 1DTK A; 3BTT I; 2HEX A; 3LDJ A; 1TFX C; 1BZ5 A; 1YKT B; 2UUX A; 2FI4 I; 2UUY B; 3AUD A; 3UIR C; 5JB7 A; 4BNR I; 1JV9 A; 2JOT A; 4PTI A; 1TOC R; 1K6U A; 1ZR0 B; 1BIK A; 2DDJ A; 1YLD B; 1P2O B; 1UUB A; 3AUE A; 1DTX A; 4TPI I; 7PTI A; 2W8X A; 5JB6 A; 1F7Z I; 3BTD I; 1SHP A; 2LFK A; 1IRH A; 1JV8 A; 1TAP A; 2KCR A; 1F5R I; 1P2Q B; 2ODY E; 2KAI I; 4U30 W; 4NTY B; 8PTI A; 1P2K I; 2LFL A; 3BYB A; 3FP8 I; 4WWY C; 4Y11 I; 1DEN A; 4ISN B; 1BRB I; 9PTI A; 3BTE I; 2IJO I; 1QLQ A; 3LDM A; 1BPI A; 1LD5 A; 4WXV C; 3M7Q B; 1FAN A; 3FP6 I; 2PTC I; 2RA3 C; 4BQD A; 3AUG A; 2ZJX A; 1T8N B; 3OTJ I; 4BD9 B; 3L33 E; 3BTW I; 3TGJ I; 1P2N B; 1YLC B; 1UUA A; 4Y10 I; 3TGK I; 2KNT A; 4ISL B; 5JB5 A; 2ZVX A; 2CA7 A; 1B0C A; 3BTH I; 2FI5 I; 2DDI A; 5PTI A; 1P2M B; 1ADZ A; 3LDI A; 3P92 E; 1TCP A; 3D65 I; 4ISO B; 3UOU B; 1BZX I; 1BTI A; 3TPI I; 3BTM I; 3FP7 J; 4NTX B; 3BTF I; 1KUN A; 6PTI A; 4DG4 C; 4NTW B; 5JB4 A; 1T8M B; 1TPA I; 2FTL I; 4Y0Y I; 3BTK I; 1OA5 5; 1KNT A; 1Y62 A; 3T62 D; 1BF0 A; 1D0D A; 1CO7 I; 1P2I I; 4U32 X; 2R9P E; 1OA6 5; 3WNY A; 1DEM A; 1D0D B; 2M99 A; 1AAP A; 1BUN B; 1EAW B; 3BTQ I; 1BPT A; 1FAK I; 3AUB A; 3AUH A; 1G6X A; 3P95 E; 1T8L B; 2TPI I; 3AUC A; 2FI3 I; 5C67 C; 1T7C B; 2M01 A; 3GYM I; 1EJM B; 2FTM B; 1AAL A; 1BTH P; 1FY8 I; 1P2J I; 2J6D A; 3CI7 A; 1CBW D; 4DTG K; 1JC6 A; 3OFW A; 1YC0 I; 1PIT A; #chains in the Genus database with same CATH homology 1TAW B; 1NAG A; 1CA0 D; 4Y0Z I; 3TGI I; 1T8O B; 3BTG I; 1BHC A; 1KIG I; 1ZJD B; 1LD6 A; 3L3T E; 1KTH A; 2TGP I; 3U1J E; 1BRC I; 1MTN D; 3AUI A; 1DTK A; 3BTT I; 2HEX A; 3LDJ A; 1TFX C; 1BZ5 A; 1YKT B; 2UUX A; 2FI4 I; 2UUY B; 3AUD A; 3UIR C; 5JB7 A; 4BNR I; 1JV9 A; 2JOT A; 4PTI A; 1TOC R; 1K6U A; 1ZR0 B; 1BIK A; 2DDJ A; 1YLD B; 1P2O B; 1UUB A; 3AUE A; 1DTX A; 4TPI I; 7PTI A; 2W8X A; 5JB6 A; 1F7Z I; 3BTD I; 1SHP A; 2LFK A; 1IRH A; 1JV8 A; 1TAP A; 2KCR A; 1F5R I; 1P2Q B; 2ODY E; 2KAI I; 4U30 W; 4NTY B; 8PTI A; 1P2K I; 2LFL A; 3BYB A; 3FP8 I; 4WWY C; 4Y11 I; 1DEN A; 4ISN B; 1BRB I; 9PTI A; 3BTE I; 2IJO I; 1QLQ A; 3LDM A; 1BPI A; 1LD5 A; 4WXV C; 3M7Q B; 1FAN A; 3FP6 I; 2PTC I; 2RA3 C; 4BQD A; 3AUG A; 2ZJX A; 1T8N B; 3OTJ I; 4BD9 B; 3L33 E; 3BTW I; 3TGJ I; 1P2N B; 1YLC B; 1UUA A; 4Y10 I; 3TGK I; 2KNT A; 4ISL B; 5JB5 A; 2ZVX A; 2CA7 A; 1B0C A; 3BTH I; 2FI5 I; 2DDI A; 5PTI A; 1P2M B; 1ADZ A; 3LDI A; 3P92 E; 1TCP A; 3D65 I; 4ISO B; 3UOU B; 1BZX I; 1BTI A; 3TPI I; 3BTM I; 3FP7 J; 4NTX B; 3BTF I; 1KUN A; 6PTI A; 4DG4 C; 4NTW B; 5JB4 A; 1T8M B; 1TPA I; 2FTL I; 4Y0Y I; 3BTK I; 1OA5 5; 1KNT A; 1Y62 A; 3T62 D; 1BF0 A; 1D0D A; 1CO7 I; 1P2I I; 4U32 X; 2R9P E; 1OA6 5; 3WNY A; 1DEM A; 1D0D B; 2M99 A; 1AAP A; 1BUN B; 1EAW B; 3BTQ I; 1BPT A; 1FAK I; 3AUB A; 3AUH A; 1G6X A; 3P95 E; 1T8L B; 2TPI I; 3AUC A; 2FI3 I; 5C67 C; 1T7C B; 2M01 A; 3GYM I; 1EJM B; 2FTM B; 1AAL A; 1BTH P; 1FY8 I; 1P2J I; 2J6D A; 3CI7 A; 1CBW D; 4DTG K; 1JC6 A; 3OFW A; 1YC0 I; 1PIT A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
