4EJ1A

Binding of nb113 camelid antibody fragment with the binary dhfr:folate complex
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihyrofolate reductase of Escherichia coli.
pubmed doi rcsb
molecule keywords Dihydrofolate reductase
molecule tags Oxidoreductase/immune system
source organism Escherichia coli
total genus 44
structure length 159
sequence length 159
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2012-04-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4ej1A00
2INQA 4QJZD 4XT4A 3TQ8A 1OHKA 4DP3A 4XE6X 3DL6A 1JOMA 3FRAX 4ELBA 2W3VA 4H97A 1DAJA 3NZDA 4G3MA 1U72A 4TU5X 4PTJA 1KMVA 3D80A 2W9GA 7DFRA 2P4GA 4IXGX 1RA2A 3JW5A 4KBNA 3K47A 4KY8A 1BZFA 1M78A 3DGAA 2HQPA 1M79A 2W3WA 2G6VA 3GI2A 1PD9A 3IRNA 3I3RA 3GHCA 3FQVA 3N0HA 4FGGA 3UM6A 1DHIA 4H98A 5JG0X 3NZCX 3GHVA 1RX5A 5ECXA 2GD9A 3QLZA 3FRDX 2OIPA 3FYWX 4QLGA 1RX9A 3NZAX 1DR1A 3DRCA 4M6KA 2HXVA 3FQOA 4Q6AA 4XT6A 1KLKA 3QGTA 3CLBA 2H2QA 3QLYA 1E26A 3SRRX 1AI9A 3FQ0A 3SQYX 1DHJA 2W9TA 3KJRA 3K2HA 1CD2A 3SA2A 4XRBA 3QL0A 4HA9A 4FHBA 3FRFX 5HT5A 4M6JA 1RG7A 1DYJA 1RC4A 4RGCA 4ELHA 1RX1A 3F8YA 4Q0EA 5HF2X 2FZJA 2FZIA 3QL3A 1DR2A 1YHOA 3CD2A 4H96A 4DDRA 3FL8A 1IA3A 3FY9X 4XT7A 4OR7A 2CIGA 3CSEA 3HJ3A 1MVTA 2W3BA 2JYBA 3TD8A 3SH2A 2HM9A 3F0VX 1DR5A 3JWCA 4ELFA 4PTHA 1DF7A 4G95A 3QLSA 1DG7A 1HFRA 1JUVA 3NXYA 3QLRA 3K45A 4KLXA 3FS6A 1DRFA 2B3ZA 1S3UA 1IA1A 3JVXA 2DRCA 3FY8X 2C2SA 1DISA 5CC9A 1AOEA 3SRUX 4IXFX 4I13A 1U70A 8DFRA 4FGHA 1RB2A 2ANOA 3S7AA 2CD2A 1DR7A 1DREA 4LAEX 2ANQA 3NXTA 3VCOA 4QLFA 2O7PA 4I1NA 4DPDA 4H95A 4KJKA 3QG2A 1RA8A 4HOFA 3D84X 2D0KA 3QYOA 4PSTA 4QI9A 1DG5A 3F0UX 4KY4A 3I8AX 1TDRA 3JSUA 5JA3A 1DHFA 2W9HA 3IA5A 4OSGA 4PDJA 5HPBA 1RX3A 5HQYA 4HA7A 1DRBA 1IA2A 3EEMA 3F0XX 2AZNA 2FZHA 4Q67A 3NZ9X 4P68A 3SGYA 3EEJA 3K74A 4XT5A 3JTWA 4NX7A 1DRAA 2OBCA 2C2TA 3F0SX 3F8ZA 4P66A 3UM8A 1RH3A 2L28A 3FRBX 4ECKA 3IRMA 1VJ3A 1DDRA 3R33A 5DFRA 3SRQX 1SEJA 5U26A 4X5FA 4CD2A 5HI6A 1DLRA 4GH8A 3FREX 4M7VA 1J3IA 1HFQA 5ECCA 3S3VA 3OCHA 5HVBA 5E8QA 4LEKX 1VDRA 4DFRA 3EX8A 1JOLA 4Q0DA 3TQBA 2D5NA 1LY4A 4EIGA 1PDBA 2KGKA 3SRSX 3FL9A 4M2XA 3EIGA 4QHVA 4X5JA 3TQAA 3NZBX 3KJSA 3ZPCA 1IA4A 3SAIA 5FDAA 3DATA 4QJCA 3QFXA 3ZPGA 1HFPA 2BL9A 3KGYA 1U71A 5HF0X 1RX7A 3F91A 4IXED 2ITHA 4M7UA 5EAJA 3EEKA 2XW7A 3GYFA 1BOZA 1S3YA 4KEBA 3NXXA 3KFYA 2BLCA 4KD7A 3DL5A 2QK8A 1RE7A 4X5GA 1LY3A 3FYVX 5HVEA 3RG9A 4XT8A 3EELA 4KJLA 3CL9A 2ZZAA 3L3RA 4HOGA 3FQCA 1DYHA 2LF1A 3NXVA 3DFRA 1DIUA 1PD8A 5HQZA 4P3RA 4EIZA 3F0QX 4EILA 2DHFA 4NX6A 2BLBA 1MVSA 3RO9A 1J3JA 1DR6A 3JWMA 1OHJA 4QLEA 3S9UA 3F0BX 1DYRA 1QZFA 3JW3A 4PSYA 3LG4A 4LAHX 4KM0A 3NTZA 1RA1A 3M08A 3FQZA 4X5HA 3QYLA 5DXVA 1DDSA 3NXOA 1DR3A 3IROA 5HSUA 1DRHA 1J3KA 3M09A 5CCCA 1M7AA 1RX8A 3IA4A 1RX6A 2W3AA 1D1GA 4KYAA 1KMSA 4PSSA 2BLAA 3QLXA 1ZDRA 6DFRA 3INVA 4KAKA 3SR5X 4KFJA 1DYIA 3NU0A 5HT4A 4P3QA 3OAFA 5U27A 3KY8A 1RA3A 4KNEA 4G8ZX 1RX2A 1S3WA 3IX9A 3Q1HA 1AO8A 3NZ6X 3E0BA 3JWFA 3NXRA 3HBBA 1DG8A 3DAUA 1S3VA 3QLWA 1RF7A 4HOEA 5HUIA 1RB3A 4KM2A 3SA1A 4EJ1A 1RA9A 4DPHA 4LAGX 3JWKA 1RD7A 3DG8A 1DR4A 4M6LA 1DLSA 3NRRA 3ROAA 1CZ3A 4X5IA 3UM5A 5HSRA 4XECX 2W3MA 4KL9A 4ELGA 1LUDA 1RX4A 3FQFA 3GHWA 4ELEA 2W9SA 3SRWX 3TQ9A 4KJJA
chains in the Genus database with same CATH superfamily
2INQA 4QJZD 4XT4A 3TQ8A 1OHKA 4DP3A 4XE6X 3DL6A 1JOMA 3FRAX 4ELBA 2W3VA 4H97A 1DAJA 3NZDA 4G3MA 1U72A 4TU5X 4PTJA 1KMVA 3D80A 2W9GA 7DFRA 2P4GA 4IXGX 1RA2A 3JW5A 4KBNA 3K47A 4KY8A 1BZFA 1M78A 3DGAA 2HQPA 1M79A 2W3WA 2G6VA 3GI2A 1PD9A 3IRNA 3I3RA 3GHCA 3FQVA 3N0HA 4FGGA 3UM6A 1DHIA 4H98A 5JG0X 3NZCX 3GHVA 1RX5A 5ECXA 2GD9A 3QLZA 3FRDX 2OIPA 3FYWX 4QLGA 1RX9A 3NZAX 1DR1A 3DRCA 4M6KA 2HXVA 3FQOA 4Q6AA 4XT6A 1KLKA 3QGTA 3CLBA 2H2QA 3QLYA 1E26A 3SRRX 1AI9A 3FQ0A 3SQYX 1DHJA 2W9TA 3KJRA 3K2HA 1CD2A 3SA2A 4XRBA 3QL0A 4HA9A 4FHBA 3FRFX 5HT5A 4M6JA 1RG7A 1DYJA 1RC4A 4RGCA 4ELHA 1RX1A 3F8YA 4Q0EA 5HF2X 2FZJA 2FZIA 3QL3A 1DR2A 1YHOA 3CD2A 4H96A 4DDRA 3FL8A 1IA3A 3FY9X 4XT7A 4OR7A 2CIGA 3CSEA 3HJ3A 1MVTA 2W3BA 2JYBA 3TD8A 3SH2A 2HM9A 3F0VX 1DR5A 3JWCA 4ELFA 4PTHA 1DF7A 4G95A 3QLSA 1DG7A 1HFRA 1JUVA 3NXYA 3QLRA 3K45A 4KLXA 3FS6A 1DRFA 2B3ZA 1S3UA 1IA1A 3JVXA 2DRCA 3FY8X 2C2SA 1DISA 5CC9A 1AOEA 3SRUX 4IXFX 4I13A 1U70A 8DFRA 4FGHA 1RB2A 2ANOA 3S7AA 2CD2A 1DR7A 1DREA 4LAEX 2ANQA 3NXTA 3VCOA 4QLFA 2O7PA 4I1NA 4DPDA 4H95A 4KJKA 3QG2A 1RA8A 4HOFA 3D84X 2D0KA 3QYOA 4PSTA 4QI9A 1DG5A 3F0UX 4KY4A 3I8AX 1TDRA 3JSUA 5JA3A 1DHFA 2W9HA 3IA5A 4OSGA 4PDJA 5HPBA 1RX3A 5HQYA 4HA7A 1DRBA 1IA2A 3EEMA 3F0XX 2AZNA 2FZHA 4Q67A 3NZ9X 4P68A 3SGYA 3EEJA 3K74A 4XT5A 3JTWA 4NX7A 1DRAA 2OBCA 2C2TA 3F0SX 3F8ZA 4P66A 3UM8A 1RH3A 2L28A 3FRBX 4ECKA 3IRMA 1VJ3A 1DDRA 3R33A 5DFRA 3SRQX 1SEJA 5U26A 4X5FA 4CD2A 5HI6A 1DLRA 4GH8A 3FREX 4M7VA 1J3IA 1HFQA 5ECCA 3S3VA 3OCHA 5HVBA 5E8QA 4LEKX 1VDRA 4DFRA 3EX8A 1JOLA 4Q0DA 3TQBA 2D5NA 1LY4A 4EIGA 1PDBA 2KGKA 3SRSX 3FL9A 4M2XA 3EIGA 4QHVA 4X5JA 3TQAA 3NZBX 3KJSA 3ZPCA 1IA4A 3SAIA 5FDAA 3DATA 4QJCA 3QFXA 3ZPGA 1HFPA 2BL9A 3KGYA 1U71A 5HF0X 1RX7A 3F91A 4IXED 2ITHA 4M7UA 5EAJA 3EEKA 2XW7A 3GYFA 1BOZA 1S3YA 4KEBA 3NXXA 3KFYA 2BLCA 4KD7A 3DL5A 2QK8A 1RE7A 4X5GA 1LY3A 3FYVX 5HVEA 3RG9A 4XT8A 3EELA 4KJLA 3CL9A 2ZZAA 3L3RA 4HOGA 3FQCA 1DYHA 2LF1A 3NXVA 3DFRA 1DIUA 1PD8A 5HQZA 4P3RA 4EIZA 3F0QX 4EILA 2DHFA 4NX6A 2BLBA 1MVSA 3RO9A 1J3JA 1DR6A 3JWMA 1OHJA 4QLEA 3S9UA 3F0BX 1DYRA 1QZFA 3JW3A 4PSYA 3LG4A 4LAHX 4KM0A 3NTZA 1RA1A 3M08A 3FQZA 4X5HA 3QYLA 5DXVA 1DDSA 3NXOA 1DR3A 3IROA 5HSUA 1DRHA 1J3KA 3M09A 5CCCA 1M7AA 1RX8A 3IA4A 1RX6A 2W3AA 1D1GA 4KYAA 1KMSA 4PSSA 2BLAA 3QLXA 1ZDRA 6DFRA 3INVA 4KAKA 3SR5X 4KFJA 1DYIA 3NU0A 5HT4A 4P3QA 3OAFA 5U27A 3KY8A 1RA3A 4KNEA 4G8ZX 1RX2A 1S3WA 3IX9A 3Q1HA 1AO8A 3NZ6X 3E0BA 3JWFA 3NXRA 3HBBA 1DG8A 3DAUA 1S3VA 3QLWA 1RF7A 4HOEA 5HUIA 1RB3A 4KM2A 3SA1A 4EJ1A 1RA9A 4DPHA 4LAGX 3JWKA 1RD7A 3DG8A 1DR4A 4M6LA 1DLSA 3NRRA 3ROAA 1CZ3A 4X5IA 3UM5A 5HSRA 4XECX 2W3MA 4KL9A 4ELGA 1LUDA 1RX4A 3FQFA 3GHWA 4ELEA 2W9SA 3SRWX 3TQ9A 4KJJA
chains in the Genus database with same CATH topology
2INQA 4QJZD 4XT4A 3TQ8A 1OHKA 4DP3A 4XE6X 3DL6A 1JOMA 3FRAX 4ELBA 2W3VA 4H97A 1DAJA 3NZDA 4G3MA 1U72A 4TU5X 4PTJA 1KMVA 3D80A 2W9GA 7DFRA 2P4GA 4IXGX 1RA2A 3JW5A 4KBNA 3K47A 4KY8A 1BZFA 1M78A 3DGAA 2HQPA 1M79A 2W3WA 2G6VA 3GI2A 1PD9A 3IRNA 3I3RA 3GHCA 3FQVA 3N0HA 4FGGA 3UM6A 1DHIA 4H98A 5JG0X 3NZCX 3GHVA 1RX5A 5ECXA 2GD9A 3QLZA 3FRDX 2OIPA 3FYWX 4QLGA 1RX9A 3NZAX 1DR1A 3DRCA 4M6KA 2HXVA 3FQOA 4Q6AA 4XT6A 1KLKA 3QGTA 3CLBA 2H2QA 3QLYA 1E26A 3SRRX 1AI9A 3FQ0A 3SQYX 1DHJA 2W9TA 3KJRA 3K2HA 1CD2A 3SA2A 4XRBA 3QL0A 4HA9A 4FHBA 3FRFX 5HT5A 4M6JA 1RG7A 1DYJA 1RC4A 4RGCA 4ELHA 1RX1A 3F8YA 4Q0EA 5HF2X 2FZJA 2FZIA 3QL3A 1DR2A 1YHOA 3CD2A 4H96A 4DDRA 3FL8A 1IA3A 3FY9X 4XT7A 4OR7A 2CIGA 3CSEA 3HJ3A 1MVTA 2W3BA 2JYBA 3TD8A 3SH2A 2HM9A 3F0VX 1DR5A 3JWCA 4ELFA 4PTHA 1DF7A 4G95A 3QLSA 1DG7A 1HFRA 1JUVA 3NXYA 3QLRA 3K45A 4KLXA 3FS6A 1DRFA 2B3ZA 1S3UA 1IA1A 3JVXA 2DRCA 3FY8X 2C2SA 1DISA 5CC9A 1AOEA 3SRUX 4IXFX 4I13A 1U70A 8DFRA 4FGHA 1RB2A 2ANOA 3S7AA 2CD2A 1DR7A 1DREA 4LAEX 2ANQA 3NXTA 3VCOA 4QLFA 2O7PA 4I1NA 4DPDA 4H95A 4KJKA 3QG2A 1RA8A 4HOFA 3D84X 2D0KA 3QYOA 4PSTA 4QI9A 1DG5A 3F0UX 4KY4A 3I8AX 1TDRA 3JSUA 5JA3A 1DHFA 2W9HA 3IA5A 4OSGA 4PDJA 5HPBA 1RX3A 5HQYA 4HA7A 1DRBA 1IA2A 3EEMA 3F0XX 2AZNA 2FZHA 4Q67A 3NZ9X 4P68A 3SGYA 3EEJA 3K74A 4XT5A 3JTWA 4NX7A 1DRAA 2OBCA 2C2TA 3F0SX 3F8ZA 4P66A 3UM8A 1RH3A 2L28A 3FRBX 4ECKA 3IRMA 1VJ3A 1DDRA 3R33A 5DFRA 3SRQX 1SEJA 5U26A 4X5FA 4CD2A 5HI6A 1DLRA 4GH8A 3FREX 4M7VA 1J3IA 1HFQA 5ECCA 3S3VA 3OCHA 5HVBA 5E8QA 4LEKX 1VDRA 4DFRA 3EX8A 1JOLA 4Q0DA 3TQBA 2D5NA 1LY4A 4EIGA 1PDBA 2KGKA 3SRSX 3FL9A 4M2XA 3EIGA 4QHVA 4X5JA 3TQAA 3NZBX 3KJSA 3ZPCA 1IA4A 3SAIA 5FDAA 3DATA 4QJCA 3QFXA 3ZPGA 1HFPA 2BL9A 3KGYA 1U71A 5HF0X 1RX7A 3F91A 4IXED 2ITHA 4M7UA 5EAJA 3EEKA 2XW7A 3GYFA 1BOZA 1S3YA 4KEBA 3NXXA 3KFYA 2BLCA 4KD7A 3DL5A 2QK8A 1RE7A 4X5GA 1LY3A 3FYVX 5HVEA 3RG9A 4XT8A 3EELA 4KJLA 3CL9A 2ZZAA 3L3RA 4HOGA 3FQCA 1DYHA 2LF1A 3NXVA 3DFRA 1DIUA 1PD8A 5HQZA 4P3RA 4EIZA 3F0QX 4EILA 2DHFA 4NX6A 2BLBA 1MVSA 3RO9A 1J3JA 1DR6A 3JWMA 1OHJA 4QLEA 3S9UA 3F0BX 1DYRA 1QZFA 3JW3A 4PSYA 3LG4A 4LAHX 4KM0A 3NTZA 1RA1A 3M08A 3FQZA 4X5HA 3QYLA 5DXVA 1DDSA 3NXOA 1DR3A 3IROA 5HSUA 1DRHA 1J3KA 3M09A 5CCCA 1M7AA 1RX8A 3IA4A 1RX6A 2W3AA 1D1GA 4KYAA 1KMSA 4PSSA 2BLAA 3QLXA 1ZDRA 6DFRA 3INVA 4KAKA 3SR5X 4KFJA 1DYIA 3NU0A 5HT4A 4P3QA 3OAFA 5U27A 3KY8A 1RA3A 4KNEA 4G8ZX 1RX2A 1S3WA 3IX9A 3Q1HA 1AO8A 3NZ6X 3E0BA 3JWFA 3NXRA 3HBBA 1DG8A 3DAUA 1S3VA 3QLWA 1RF7A 4HOEA 5HUIA 1RB3A 4KM2A 3SA1A 4EJ1A 1RA9A 4DPHA 4LAGX 3JWKA 1RD7A 3DG8A 1DR4A 4M6LA 1DLSA 3NRRA 3ROAA 1CZ3A 4X5IA 3UM5A 5HSRA 4XECX 2W3MA 4KL9A 4ELGA 1LUDA 1RX4A 3FQFA 3GHWA 4ELEA 2W9SA 3SRWX 3TQ9A 4KJJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2INQ A;  4QJZ D;  4XT4 A;  3TQ8 A;  1OHK A;  4DP3 A;  4XE6 X;  3DL6 A;  1JOM A;  3FRA X;  4ELB A;  2W3V A;  4H97 A;  1DAJ A;  3NZD A;  4G3M A;  1U72 A;  4TU5 X;  4PTJ A;  1KMV A;  3D80 A;  2W9G A;  7DFR A;  2P4G A;  4IXG X;  1RA2 A;  3JW5 A;  4KBN A;  3K47 A;  4KY8 A;  1BZF A;  1M78 A;  3DGA A;  2HQP A;  1M79 A;  2W3W A;  2G6V A;  3GI2 A;  1PD9 A;  3IRN A;  3I3R A;  3GHC A;  3FQV A;  3N0H A;  4FGG A;  3UM6 A;  1DHI A;  4H98 A;  5JG0 X;  3NZC X;  3GHV A;  1RX5 A;  5ECX A;  2GD9 A;  3QLZ A;  3FRD X;  2OIP A;  3FYW X;  4QLG A;  1RX9 A;  3NZA X;  1DR1 A;  3DRC A;  4M6K A;  2HXV A;  3FQO A;  4Q6A A;  4XT6 A;  1KLK A;  3QGT A;  3CLB A;  2H2Q A;  3QLY A;  1E26 A;  3SRR X;  1AI9 A;  3FQ0 A;  3SQY X;  1DHJ A;  2W9T A;  3KJR A;  3K2H A;  1CD2 A;  3SA2 A;  4XRB A;  3QL0 A;  4HA9 A;  4FHB A;  3FRF X;  5HT5 A;  4M6J A;  1RG7 A;  1DYJ A;  1RC4 A;  4RGC A;  4ELH A;  1RX1 A;  3F8Y A;  4Q0E A;  5HF2 X;  2FZJ A;  2FZI A;  3QL3 A;  1DR2 A;  1YHO A;  3CD2 A;  4H96 A;  4DDR A;  3FL8 A;  1IA3 A;  3FY9 X;  4XT7 A;  4OR7 A;  2CIG A;  3CSE A;  3HJ3 A;  1MVT A;  2W3B A;  2JYB A;  3TD8 A;  3SH2 A;  2HM9 A;  3F0V X;  1DR5 A;  3JWC A;  4ELF A;  4PTH A;  1DF7 A;  4G95 A;  3QLS A;  1DG7 A;  1HFR A;  1JUV A;  3NXY A;  3QLR A;  3K45 A;  4KLX A;  3FS6 A;  1DRF A;  2B3Z A;  1S3U A;  1IA1 A;  3JVX A;  2DRC A;  3FY8 X;  2C2S A;  1DIS A;  5CC9 A;  1AOE A;  3SRU X;  4IXF X;  4I13 A;  1U70 A;  8DFR A;  4FGH A;  1RB2 A;  2ANO A;  3S7A A;  2CD2 A;  1DR7 A;  1DRE A;  4LAE X;  2ANQ A;  3NXT A;  3VCO A;  4QLF A;  2O7P A;  4I1N A;  4DPD A;  4H95 A;  4KJK A;  3QG2 A;  1RA8 A;  4HOF A;  3D84 X;  2D0K A;  3QYO A;  4PST A;  4QI9 A;  1DG5 A;  3F0U X;  4KY4 A;  3I8A X;  1TDR A;  3JSU A;  5JA3 A;  1DHF A;  2W9H A;  3IA5 A;  4OSG A;  4PDJ A;  5HPB A;  1RX3 A;  5HQY A;  4HA7 A;  1DRB A;  1IA2 A;  3EEM A;  3F0X X;  2AZN A;  2FZH A;  4Q67 A;  3NZ9 X;  4P68 A;  3SGY A;  3EEJ A;  3K74 A;  4XT5 A;  3JTW A;  4NX7 A;  1DRA A;  2OBC A;  2C2T A;  3F0S X;  3F8Z A;  4P66 A;  3UM8 A;  1RH3 A;  2L28 A;  3FRB X;  4ECK A;  3IRM A;  1VJ3 A;  1DDR A;  3R33 A;  5DFR A;  3SRQ X;  1SEJ A;  5U26 A;  4X5F A;  4CD2 A;  5HI6 A;  1DLR A;  4GH8 A;  3FRE X;  4M7V A;  1J3I A;  1HFQ A;  5ECC A;  3S3V A;  3OCH A;  5HVB A;  5E8Q A;  4LEK X;  1VDR A;  4DFR A;  3EX8 A;  1JOL A;  4Q0D A;  3TQB A;  2D5N A;  1LY4 A;  4EIG A;  1PDB A;  2KGK A;  3SRS X;  3FL9 A;  4M2X A;  3EIG A;  4QHV A;  4X5J A;  3TQA A;  3NZB X;  3KJS A;  3ZPC A;  1IA4 A;  3SAI A;  5FDA A;  3DAT A;  4QJC A;  3QFX A;  3ZPG A;  1HFP A;  2BL9 A;  3KGY A;  1U71 A;  5HF0 X;  1RX7 A;  3F91 A;  4IXE D;  2ITH A;  4M7U A;  5EAJ A;  3EEK A;  2XW7 A;  3GYF A;  1BOZ A;  1S3Y A;  4KEB A;  3NXX A;  3KFY A;  2BLC A;  4KD7 A;  3DL5 A;  2QK8 A;  1RE7 A;  4X5G A;  1LY3 A;  3FYV X;  5HVE A;  3RG9 A;  4XT8 A;  3EEL A;  4KJL A;  3CL9 A;  2ZZA A;  3L3R A;  4HOG A;  3FQC A;  1DYH A;  2LF1 A;  3NXV A;  3DFR A;  1DIU A;  1PD8 A;  5HQZ A;  4P3R A;  4EIZ A;  3F0Q X;  4EIL A;  2DHF A;  4NX6 A;  2BLB A;  1MVS A;  3RO9 A;  1J3J A;  1DR6 A;  3JWM A;  1OHJ A;  4QLE A;  3S9U A;  3F0B X;  1DYR A;  1QZF A;  3JW3 A;  4PSY A;  3LG4 A;  4LAH X;  4KM0 A;  3NTZ A;  1RA1 A;  3M08 A;  3FQZ A;  4X5H A;  3QYL A;  5DXV A;  1DDS A;  3NXO A;  1DR3 A;  3IRO A;  5HSU A;  1DRH A;  1J3K A;  3M09 A;  5CCC A;  1M7A A;  1RX8 A;  3IA4 A;  1RX6 A;  2W3A A;  1D1G A;  4KYA A;  1KMS A;  4PSS A;  2BLA A;  3QLX A;  1ZDR A;  6DFR A;  3INV A;  4KAK A;  3SR5 X;  4KFJ A;  1DYI A;  3NU0 A;  5HT4 A;  4P3Q A;  3OAF A;  5U27 A;  3KY8 A;  1RA3 A;  4KNE A;  4G8Z X;  1RX2 A;  1S3W A;  3IX9 A;  3Q1H A;  1AO8 A;  3NZ6 X;  3E0B A;  3JWF A;  3NXR A;  3HBB A;  1DG8 A;  3DAU A;  1S3V A;  3QLW A;  1RF7 A;  4HOE A;  5HUI A;  1RB3 A;  4KM2 A;  3SA1 A;  4EJ1 A;  1RA9 A;  4DPH A;  4LAG X;  3JWK A;  1RD7 A;  3DG8 A;  1DR4 A;  4M6L A;  1DLS A;  3NRR A;  3ROA A;  1CZ3 A;  4X5I A;  3UM5 A;  5HSR A;  4XEC X;  2W3M A;  4KL9 A;  4ELG A;  1LUD A;  1RX4 A;  3FQF A;  3GHW A;  4ELE A;  2W9S A;  3SRW X;  3TQ9 A;  4KJJ A; 
#chains in the Genus database with same CATH topology
 2INQ A;  4QJZ D;  4XT4 A;  3TQ8 A;  1OHK A;  4DP3 A;  4XE6 X;  3DL6 A;  1JOM A;  3FRA X;  4ELB A;  2W3V A;  4H97 A;  1DAJ A;  3NZD A;  4G3M A;  1U72 A;  4TU5 X;  4PTJ A;  1KMV A;  3D80 A;  2W9G A;  7DFR A;  2P4G A;  4IXG X;  1RA2 A;  3JW5 A;  4KBN A;  3K47 A;  4KY8 A;  1BZF A;  1M78 A;  3DGA A;  2HQP A;  1M79 A;  2W3W A;  2G6V A;  3GI2 A;  1PD9 A;  3IRN A;  3I3R A;  3GHC A;  3FQV A;  3N0H A;  4FGG A;  3UM6 A;  1DHI A;  4H98 A;  5JG0 X;  3NZC X;  3GHV A;  1RX5 A;  5ECX A;  2GD9 A;  3QLZ A;  3FRD X;  2OIP A;  3FYW X;  4QLG A;  1RX9 A;  3NZA X;  1DR1 A;  3DRC A;  4M6K A;  2HXV A;  3FQO A;  4Q6A A;  4XT6 A;  1KLK A;  3QGT A;  3CLB A;  2H2Q A;  3QLY A;  1E26 A;  3SRR X;  1AI9 A;  3FQ0 A;  3SQY X;  1DHJ A;  2W9T A;  3KJR A;  3K2H A;  1CD2 A;  3SA2 A;  4XRB A;  3QL0 A;  4HA9 A;  4FHB A;  3FRF X;  5HT5 A;  4M6J A;  1RG7 A;  1DYJ A;  1RC4 A;  4RGC A;  4ELH A;  1RX1 A;  3F8Y A;  4Q0E A;  5HF2 X;  2FZJ A;  2FZI A;  3QL3 A;  1DR2 A;  1YHO A;  3CD2 A;  4H96 A;  4DDR A;  3FL8 A;  1IA3 A;  3FY9 X;  4XT7 A;  4OR7 A;  2CIG A;  3CSE A;  3HJ3 A;  1MVT A;  2W3B A;  2JYB A;  3TD8 A;  3SH2 A;  2HM9 A;  3F0V X;  1DR5 A;  3JWC A;  4ELF A;  4PTH A;  1DF7 A;  4G95 A;  3QLS A;  1DG7 A;  1HFR A;  1JUV A;  3NXY A;  3QLR A;  3K45 A;  4KLX A;  3FS6 A;  1DRF A;  2B3Z A;  1S3U A;  1IA1 A;  3JVX A;  2DRC A;  3FY8 X;  2C2S A;  1DIS A;  5CC9 A;  1AOE A;  3SRU X;  4IXF X;  4I13 A;  1U70 A;  8DFR A;  4FGH A;  1RB2 A;  2ANO A;  3S7A A;  2CD2 A;  1DR7 A;  1DRE A;  4LAE X;  2ANQ A;  3NXT A;  3VCO A;  4QLF A;  2O7P A;  4I1N A;  4DPD A;  4H95 A;  4KJK A;  3QG2 A;  1RA8 A;  4HOF A;  3D84 X;  2D0K A;  3QYO A;  4PST A;  4QI9 A;  1DG5 A;  3F0U X;  4KY4 A;  3I8A X;  1TDR A;  3JSU A;  5JA3 A;  1DHF A;  2W9H A;  3IA5 A;  4OSG A;  4PDJ A;  5HPB A;  1RX3 A;  5HQY A;  4HA7 A;  1DRB A;  1IA2 A;  3EEM A;  3F0X X;  2AZN A;  2FZH A;  4Q67 A;  3NZ9 X;  4P68 A;  3SGY A;  3EEJ A;  3K74 A;  4XT5 A;  3JTW A;  4NX7 A;  1DRA A;  2OBC A;  2C2T A;  3F0S X;  3F8Z A;  4P66 A;  3UM8 A;  1RH3 A;  2L28 A;  3FRB X;  4ECK A;  3IRM A;  1VJ3 A;  1DDR A;  3R33 A;  5DFR A;  3SRQ X;  1SEJ A;  5U26 A;  4X5F A;  4CD2 A;  5HI6 A;  1DLR A;  4GH8 A;  3FRE X;  4M7V A;  1J3I A;  1HFQ A;  5ECC A;  3S3V A;  3OCH A;  5HVB A;  5E8Q A;  4LEK X;  1VDR A;  4DFR A;  3EX8 A;  1JOL A;  4Q0D A;  3TQB A;  2D5N A;  1LY4 A;  4EIG A;  1PDB A;  2KGK A;  3SRS X;  3FL9 A;  4M2X A;  3EIG A;  4QHV A;  4X5J A;  3TQA A;  3NZB X;  3KJS A;  3ZPC A;  1IA4 A;  3SAI A;  5FDA A;  3DAT A;  4QJC A;  3QFX A;  3ZPG A;  1HFP A;  2BL9 A;  3KGY A;  1U71 A;  5HF0 X;  1RX7 A;  3F91 A;  4IXE D;  2ITH A;  4M7U A;  5EAJ A;  3EEK A;  2XW7 A;  3GYF A;  1BOZ A;  1S3Y A;  4KEB A;  3NXX A;  3KFY A;  2BLC A;  4KD7 A;  3DL5 A;  2QK8 A;  1RE7 A;  4X5G A;  1LY3 A;  3FYV X;  5HVE A;  3RG9 A;  4XT8 A;  3EEL A;  4KJL A;  3CL9 A;  2ZZA A;  3L3R A;  4HOG A;  3FQC A;  1DYH A;  2LF1 A;  3NXV A;  3DFR A;  1DIU A;  1PD8 A;  5HQZ A;  4P3R A;  4EIZ A;  3F0Q X;  4EIL A;  2DHF A;  4NX6 A;  2BLB A;  1MVS A;  3RO9 A;  1J3J A;  1DR6 A;  3JWM A;  1OHJ A;  4QLE A;  3S9U A;  3F0B X;  1DYR A;  1QZF A;  3JW3 A;  4PSY A;  3LG4 A;  4LAH X;  4KM0 A;  3NTZ A;  1RA1 A;  3M08 A;  3FQZ A;  4X5H A;  3QYL A;  5DXV A;  1DDS A;  3NXO A;  1DR3 A;  3IRO A;  5HSU A;  1DRH A;  1J3K A;  3M09 A;  5CCC A;  1M7A A;  1RX8 A;  3IA4 A;  1RX6 A;  2W3A A;  1D1G A;  4KYA A;  1KMS A;  4PSS A;  2BLA A;  3QLX A;  1ZDR A;  6DFR A;  3INV A;  4KAK A;  3SR5 X;  4KFJ A;  1DYI A;  3NU0 A;  5HT4 A;  4P3Q A;  3OAF A;  5U27 A;  3KY8 A;  1RA3 A;  4KNE A;  4G8Z X;  1RX2 A;  1S3W A;  3IX9 A;  3Q1H A;  1AO8 A;  3NZ6 X;  3E0B A;  3JWF A;  3NXR A;  3HBB A;  1DG8 A;  3DAU A;  1S3V A;  3QLW A;  1RF7 A;  4HOE A;  5HUI A;  1RB3 A;  4KM2 A;  3SA1 A;  4EJ1 A;  1RA9 A;  4DPH A;  4LAG X;  3JWK A;  1RD7 A;  3DG8 A;  1DR4 A;  4M6L A;  1DLS A;  3NRR A;  3ROA A;  1CZ3 A;  4X5I A;  3UM5 A;  5HSR A;  4XEC X;  2W3M A;  4KL9 A;  4ELG A;  1LUD A;  1RX4 A;  3FQF A;  3GHW A;  4ELE A;  2W9S A;  3SRW X;  3TQ9 A;  4KJJ A; 
#chains in the Genus database with same CATH homology
 2INQ A;  4QJZ D;  4XT4 A;  3TQ8 A;  1OHK A;  4DP3 A;  4XE6 X;  3DL6 A;  1JOM A;  3FRA X;  4ELB A;  2W3V A;  4H97 A;  1DAJ A;  3NZD A;  4G3M A;  1U72 A;  4TU5 X;  4PTJ A;  1KMV A;  3D80 A;  2W9G A;  7DFR A;  2P4G A;  4IXG X;  1RA2 A;  3JW5 A;  4KBN A;  3K47 A;  4KY8 A;  1BZF A;  1M78 A;  3DGA A;  2HQP A;  1M79 A;  2W3W A;  2G6V A;  3GI2 A;  1PD9 A;  3IRN A;  3I3R A;  3GHC A;  3FQV A;  3N0H A;  4FGG A;  3UM6 A;  1DHI A;  4H98 A;  5JG0 X;  3NZC X;  3GHV A;  1RX5 A;  5ECX A;  2GD9 A;  3QLZ A;  3FRD X;  2OIP A;  3FYW X;  4QLG A;  1RX9 A;  3NZA X;  1DR1 A;  3DRC A;  4M6K A;  2HXV A;  3FQO A;  4Q6A A;  4XT6 A;  1KLK A;  3QGT A;  3CLB A;  2H2Q A;  3QLY A;  1E26 A;  3SRR X;  1AI9 A;  3FQ0 A;  3SQY X;  1DHJ A;  2W9T A;  3KJR A;  3K2H A;  1CD2 A;  3SA2 A;  4XRB A;  3QL0 A;  4HA9 A;  4FHB A;  3FRF X;  5HT5 A;  4M6J A;  1RG7 A;  1DYJ A;  1RC4 A;  4RGC A;  4ELH A;  1RX1 A;  3F8Y A;  4Q0E A;  5HF2 X;  2FZJ A;  2FZI A;  3QL3 A;  1DR2 A;  1YHO A;  3CD2 A;  4H96 A;  4DDR A;  3FL8 A;  1IA3 A;  3FY9 X;  4XT7 A;  4OR7 A;  2CIG A;  3CSE A;  3HJ3 A;  1MVT A;  2W3B A;  2JYB A;  3TD8 A;  3SH2 A;  2HM9 A;  3F0V X;  1DR5 A;  3JWC A;  4ELF A;  4PTH A;  1DF7 A;  4G95 A;  3QLS A;  1DG7 A;  1HFR A;  1JUV A;  3NXY A;  3QLR A;  3K45 A;  4KLX A;  3FS6 A;  1DRF A;  2B3Z A;  1S3U A;  1IA1 A;  3JVX A;  2DRC A;  3FY8 X;  2C2S A;  1DIS A;  5CC9 A;  1AOE A;  3SRU X;  4IXF X;  4I13 A;  1U70 A;  8DFR A;  4FGH A;  1RB2 A;  2ANO A;  3S7A A;  2CD2 A;  1DR7 A;  1DRE A;  4LAE X;  2ANQ A;  3NXT A;  3VCO A;  4QLF A;  2O7P A;  4I1N A;  4DPD A;  4H95 A;  4KJK A;  3QG2 A;  1RA8 A;  4HOF A;  3D84 X;  2D0K A;  3QYO A;  4PST A;  4QI9 A;  1DG5 A;  3F0U X;  4KY4 A;  3I8A X;  1TDR A;  3JSU A;  5JA3 A;  1DHF A;  2W9H A;  3IA5 A;  4OSG A;  4PDJ A;  5HPB A;  1RX3 A;  5HQY A;  4HA7 A;  1DRB A;  1IA2 A;  3EEM A;  3F0X X;  2AZN A;  2FZH A;  4Q67 A;  3NZ9 X;  4P68 A;  3SGY A;  3EEJ A;  3K74 A;  4XT5 A;  3JTW A;  4NX7 A;  1DRA A;  2OBC A;  2C2T A;  3F0S X;  3F8Z A;  4P66 A;  3UM8 A;  1RH3 A;  2L28 A;  3FRB X;  4ECK A;  3IRM A;  1VJ3 A;  1DDR A;  3R33 A;  5DFR A;  3SRQ X;  1SEJ A;  5U26 A;  4X5F A;  4CD2 A;  5HI6 A;  1DLR A;  4GH8 A;  3FRE X;  4M7V A;  1J3I A;  1HFQ A;  5ECC A;  3S3V A;  3OCH A;  5HVB A;  5E8Q A;  4LEK X;  1VDR A;  4DFR A;  3EX8 A;  1JOL A;  4Q0D A;  3TQB A;  2D5N A;  1LY4 A;  4EIG A;  1PDB A;  2KGK A;  3SRS X;  3FL9 A;  4M2X A;  3EIG A;  4QHV A;  4X5J A;  3TQA A;  3NZB X;  3KJS A;  3ZPC A;  1IA4 A;  3SAI A;  5FDA A;  3DAT A;  4QJC A;  3QFX A;  3ZPG A;  1HFP A;  2BL9 A;  3KGY A;  1U71 A;  5HF0 X;  1RX7 A;  3F91 A;  4IXE D;  2ITH A;  4M7U A;  5EAJ A;  3EEK A;  2XW7 A;  3GYF A;  1BOZ A;  1S3Y A;  4KEB A;  3NXX A;  3KFY A;  2BLC A;  4KD7 A;  3DL5 A;  2QK8 A;  1RE7 A;  4X5G A;  1LY3 A;  3FYV X;  5HVE A;  3RG9 A;  4XT8 A;  3EEL A;  4KJL A;  3CL9 A;  2ZZA A;  3L3R A;  4HOG A;  3FQC A;  1DYH A;  2LF1 A;  3NXV A;  3DFR A;  1DIU A;  1PD8 A;  5HQZ A;  4P3R A;  4EIZ A;  3F0Q X;  4EIL A;  2DHF A;  4NX6 A;  2BLB A;  1MVS A;  3RO9 A;  1J3J A;  1DR6 A;  3JWM A;  1OHJ A;  4QLE A;  3S9U A;  3F0B X;  1DYR A;  1QZF A;  3JW3 A;  4PSY A;  3LG4 A;  4LAH X;  4KM0 A;  3NTZ A;  1RA1 A;  3M08 A;  3FQZ A;  4X5H A;  3QYL A;  5DXV A;  1DDS A;  3NXO A;  1DR3 A;  3IRO A;  5HSU A;  1DRH A;  1J3K A;  3M09 A;  5CCC A;  1M7A A;  1RX8 A;  3IA4 A;  1RX6 A;  2W3A A;  1D1G A;  4KYA A;  1KMS A;  4PSS A;  2BLA A;  3QLX A;  1ZDR A;  6DFR A;  3INV A;  4KAK A;  3SR5 X;  4KFJ A;  1DYI A;  3NU0 A;  5HT4 A;  4P3Q A;  3OAF A;  5U27 A;  3KY8 A;  1RA3 A;  4KNE A;  4G8Z X;  1RX2 A;  1S3W A;  3IX9 A;  3Q1H A;  1AO8 A;  3NZ6 X;  3E0B A;  3JWF A;  3NXR A;  3HBB A;  1DG8 A;  3DAU A;  1S3V A;  3QLW A;  1RF7 A;  4HOE A;  5HUI A;  1RB3 A;  4KM2 A;  3SA1 A;  4EJ1 A;  1RA9 A;  4DPH A;  4LAG X;  3JWK A;  1RD7 A;  3DG8 A;  1DR4 A;  4M6L A;  1DLS A;  3NRR A;  3ROA A;  1CZ3 A;  4X5I A;  3UM5 A;  5HSR A;  4XEC X;  2W3M A;  4KL9 A;  4ELG A;  1LUD A;  1RX4 A;  3FQF A;  3GHW A;  4ELE A;  2W9S A;  3SRW X;  3TQ9 A;  4KJJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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