4EPUA

Ang1 fibrinogen-related domain (fred)
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
215
structure length
215
Chain Sequence
FRDCADVYQAGFNKSGIYTIYINNMPEPKKVFCNMDVNGGGWTVIQHREDGSLDFQRGWKEYKMGFGNPSGEYWLGNEFIFAITSQRQYMLRIELMDWEGNRAYSQYDRFHIGNEKQNYRLYLKGHTGTAGKQSSLILHGADFSTKDADNDNCMCKCALMLTGGWWFDACGPSNLNGMFYTAGQNHGKLNGIKWHYFKGPSYSLRSTTMMIRPLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Biochemical and structural characterization of the Ang1 fibrinogen-related domain
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Angiopoietin-1
total genus 62
structure length 215
sequence length 215
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-04-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 4epuA01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 4epuA02
3HUSC 1RE4C 1FZCB 3BVHB 2J3GA 2JHIF 4EPUA 1JC9A 2Q9IB 1LT9B 1N73C 2HLOC 1RE3B 1LWUC 2J61B 4R9JA 1FZBC 2J0YA 3H32B 2XNXB 1FZBB 2FFDC 2FFDB 2WNPF 2J60A 4ZFGA 2JHLF 2J61A 2HPCB 1FZCC 2H43B 3BVHC 2J3OA 1FZGB 2Q9IC 1LT9C 2J3FA 1Z3SA 1RE3C 4M7HA 1FICA 1LTJB 4M7FA 2OYIB 2HODB 3H32C 2XNXC 2J3UA 1Z3UA 2JHMF 2JHHC 1FZAB 2HPCC 2H43C 1FZDA 2Z4EB 2OYHB 3GHGC 2J5ZA 1FZGC 1RF0B 2JHKF 1N86C 1M1JB 1N86B 1FZFB 1LTJC 2OYIC 2HODC 4JZCA 1FZEB 3E1IB 2GY7A 2J2PA 2FIBA 1FIDA 4NYTA 1RF1B 1FZAC 3HUSB 1RE4B 2Z4EC 2OYHC 2J0HA 3FIBA 2J3FD 2D39A 4JYOX 1FIBA 1RF0C 1M1JC 1FZFC 1N73B 4R9TA 2J1GA 2HLOB 2J0GA 1LWUB 1FZEC 3E1IC 2J64A 1RF1C
chains in the Genus database with same CATH superfamily
3HUSC 1RE4C 1FZCB 3BVHB 2J3GA 2JHIF 4EPUA 1JC9A 2Q9IB 1LT9B 1N73C 2HLOC 1RE3B 1LWUC 2J61B 4R9JA 1FZBC 2J0YA 3H32B 2XNXB 1FZBB 2FFDC 2FFDB 2WNPF 2J60A 4ZFGA 2JHLF 2J61A 2HPCB 1FZCC 2H43B 3BVHC 2J3OA 3GHGB 1FZGB 2Q9IC 1LT9C 2J3FA 1Z3SA 1RE3C 4M7HA 1FICA 1LTJB 4M7FA 2OYIB 2HODB 3H32C 2XNXC 2J3UA 1Z3UA 2JHMF 2JHHC 1FZAB 2HPCC 2H43C 1FZDA 2Z4EB 2OYHB 3GHGC 2J5ZA 1FZGC 1RF0B 2JHKF 1N86C 1M1JB 1N86B 1FZFB 1LTJC 2OYIC 2HODC 4JZCA 1FZEB 3E1IB 2GY7A 2J2PA 2FIBA 1FIDA 4NYTA 1RF1B 1FZAC 3HUSB 1RE4B 2Z4EC 2OYHC 2J0HA 3FIBA 2J3FD 2D39A 4JYOX 1FIBA 1RF0C 1M1JC 1FZFC 1N73B 4R9TA 2J1GA 2HLOB 2J0GA 1LWUB 1FZEC 3E1IC 2J64A 1RF1C
chains in the Genus database with same CATH topology
3HUSC 1RE4C 1FZCB 3BVHB 2J3GA 2JHIF 4EPUA 1JC9A 2Q9IB 1LT9B 1N73C 2HLOC 1RE3B 1LWUC 2J61B 4R9JA 1FZBC 2J0YA 3H32B 2XNXB 1FZBB 2FFDC 2FFDB 2WNPF 2J60A 4ZFGA 2JHLF 2J61A 2HPCB 1FZCC 2H43B 3BVHC 2J3OA 1FZGB 2Q9IC 1LT9C 2J3FA 1Z3SA 1RE3C 4M7HA 1FICA 1LTJB 4M7FA 2OYIB 2HODB 3H32C 2XNXC 2J3UA 1Z3UA 2JHMF 2JHHC 1FZAB 2HPCC 2H43C 1FZDA 2Z4EB 2OYHB 3GHGC 2J5ZA 1FZGC 1RF0B 2JHKF 1N86C 1M1JB 1N86B 1FZFB 1LTJC 2OYIC 2HODC 4JZCA 1FZEB 3E1IB 2GY7A 2J2PA 2FIBA 1FIDA 4NYTA 1RF1B 1FZAC 3HUSB 1RE4B 2Z4EC 2OYHC 2J0HA 3FIBA 2J3FD 2D39A 4JYOX 1FIBA 1RF0C 1M1JC 1FZFC 1N73B 4R9TA 2J1GA 2HLOB 2J0GA 1LWUB 1FZEC 3E1IC 2J64A 1RF1C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HUS C;  1RE4 C;  1FZC B;  3BVH B;  2J3G A;  2JHI F;  4EPU A;  1JC9 A;  2Q9I B;  1LT9 B;  1N73 C;  2HLO C;  1RE3 B;  1LWU C;  2J61 B;  4R9J A;  1FZB C;  2J0Y A;  3H32 B;  2XNX B;  1FZB B;  2FFD C;  2FFD B;  2WNP F;  2J60 A;  4ZFG A;  2JHL F;  2J61 A;  2HPC B;  1FZC C;  2H43 B;  3BVH C;  2J3O A;  1FZG B;  2Q9I C;  1LT9 C;  2J3F A;  1Z3S A;  1RE3 C;  4M7H A;  1FIC A;  1LTJ B;  4M7F A;  2OYI B;  2HOD B;  3H32 C;  2XNX C;  2J3U A;  1Z3U A;  2JHM F;  2JHH C;  1FZA B;  2HPC C;  2H43 C;  1FZD A;  2Z4E B;  2OYH B;  3GHG C;  2J5Z A;  1FZG C;  1RF0 B;  2JHK F;  1N86 C;  1M1J B;  1N86 B;  1FZF B;  1LTJ C;  2OYI C;  2HOD C;  4JZC A;  1FZE B;  3E1I B;  2GY7 A;  2J2P A;  2FIB A;  1FID A;  4NYT A;  1RF1 B;  1FZA C;  3HUS B;  1RE4 B;  2Z4E C;  2OYH C;  2J0H A;  3FIB A;  2J3F D;  2D39 A;  4JYO X;  1FIB A;  1RF0 C;  1M1J C;  1FZF C;  1N73 B;  4R9T A;  2J1G A;  2HLO B;  2J0G A;  1LWU B;  1FZE C;  3E1I C;  2J64 A;  1RF1 C; 
#chains in the Genus database with same CATH topology
 3HUS C;  1RE4 C;  1FZC B;  3BVH B;  2J3G A;  2JHI F;  4EPU A;  1JC9 A;  2Q9I B;  1LT9 B;  1N73 C;  2HLO C;  1RE3 B;  1LWU C;  2J61 B;  4R9J A;  1FZB C;  2J0Y A;  3H32 B;  2XNX B;  1FZB B;  2FFD C;  2FFD B;  2WNP F;  2J60 A;  4ZFG A;  2JHL F;  2J61 A;  2HPC B;  1FZC C;  2H43 B;  3BVH C;  2J3O A;  3GHG B;  1FZG B;  2Q9I C;  1LT9 C;  2J3F A;  1Z3S A;  1RE3 C;  4M7H A;  1FIC A;  1LTJ B;  4M7F A;  2OYI B;  2HOD B;  3H32 C;  2XNX C;  2J3U A;  1Z3U A;  2JHM F;  2JHH C;  1FZA B;  2HPC C;  2H43 C;  1FZD A;  2Z4E B;  2OYH B;  3GHG C;  2J5Z A;  1FZG C;  1RF0 B;  2JHK F;  1N86 C;  1M1J B;  1N86 B;  1FZF B;  1LTJ C;  2OYI C;  2HOD C;  4JZC A;  1FZE B;  3E1I B;  2GY7 A;  2J2P A;  2FIB A;  1FID A;  4NYT A;  1RF1 B;  1FZA C;  3HUS B;  1RE4 B;  2Z4E C;  2OYH C;  2J0H A;  3FIB A;  2J3F D;  2D39 A;  4JYO X;  1FIB A;  1RF0 C;  1M1J C;  1FZF C;  1N73 B;  4R9T A;  2J1G A;  2HLO B;  2J0G A;  1LWU B;  1FZE C;  3E1I C;  2J64 A;  1RF1 C; 
#chains in the Genus database with same CATH homology
 3HUS C;  1RE4 C;  1FZC B;  3BVH B;  2J3G A;  2JHI F;  4EPU A;  1JC9 A;  2Q9I B;  1LT9 B;  1N73 C;  2HLO C;  1RE3 B;  1LWU C;  2J61 B;  4R9J A;  1FZB C;  2J0Y A;  3H32 B;  2XNX B;  1FZB B;  2FFD C;  2FFD B;  2WNP F;  2J60 A;  4ZFG A;  2JHL F;  2J61 A;  2HPC B;  1FZC C;  2H43 B;  3BVH C;  2J3O A;  1FZG B;  2Q9I C;  1LT9 C;  2J3F A;  1Z3S A;  1RE3 C;  4M7H A;  1FIC A;  1LTJ B;  4M7F A;  2OYI B;  2HOD B;  3H32 C;  2XNX C;  2J3U A;  1Z3U A;  2JHM F;  2JHH C;  1FZA B;  2HPC C;  2H43 C;  1FZD A;  2Z4E B;  2OYH B;  3GHG C;  2J5Z A;  1FZG C;  1RF0 B;  2JHK F;  1N86 C;  1M1J B;  1N86 B;  1FZF B;  1LTJ C;  2OYI C;  2HOD C;  4JZC A;  1FZE B;  3E1I B;  2GY7 A;  2J2P A;  2FIB A;  1FID A;  4NYT A;  1RF1 B;  1FZA C;  3HUS B;  1RE4 B;  2Z4E C;  2OYH C;  2J0H A;  3FIB A;  2J3F D;  2D39 A;  4JYO X;  1FIB A;  1RF0 C;  1M1J C;  1FZF C;  1N73 B;  4R9T A;  2J1G A;  2HLO B;  2J0G A;  1LWU B;  1FZE C;  3E1I C;  2J64 A;  1RF1 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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