4ERSA

A molecular basis for negative regulation of the glucagon receptor
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
96
structure length
96
Chain Sequence
VMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQCQM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis for negative regulation of the glucagon receptor.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords Fab light chain
total genus 23
structure length 96
sequence length 96
ec nomenclature
pdb deposition date 2012-04-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.1240.10 Few Secondary Structures Irregular Hormone receptor fold GPCR, family 2, extracellular hormone receptor domain 4ersA00
2JNCA 3EHTA 5II0A 3IOLA 3N7RA 2QKHA 3EHUA 4ERSA 2JNDA 4LF3C 3C5TA 3AQFB 2XDGA 1U34A 3C4MA 3N7SA 2JODA 4HJ0A 3EHSA 3N7PA 2L27A 4ZGMA 3H3GA 3C59A 3L2JA 4DLQA 4DLOA
chains in the Genus database with same CATH superfamily
2JNCA 3EHTA 5II0A 3IOLA 3N7RA 2QKHA 3EHUA 4ERSA 2JNDA 4LF3C 3C5TA 3AQFB 2XDGA 1U34A 3C4MA 3N7SA 2JODA 4HJ0A 3EHSA 3N7PA 2L27A 4ZGMA 3H3GA 3C59A 3L2JA 4DLQA 4DLOA
chains in the Genus database with same CATH topology
2JNCA 3EHTA 5II0A 3IOLA 3N7RA 2QKHA 3EHUA 4ERSA 2JNDA 4LF3C 3C5TA 3AQFB 2XDGA 1U34A 3C4MA 3N7SA 2JODA 4HJ0A 3EHSA 3N7PA 2L27A 4ZGMA 3H3GA 3C59A 3L2JA 4DLQA 4DLOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JNC A;  3EHT A;  5II0 A;  3IOL A;  3N7R A;  2QKH A;  3EHU A;  4ERS A;  2JND A;  4LF3 C;  3C5T A;  3AQF B;  2XDG A;  1U34 A;  3C4M A;  3N7S A;  2JOD A;  4HJ0 A;  3EHS A;  3N7P A;  2L27 A;  4ZGM A;  3H3G A;  3C59 A;  3L2J A;  4DLQ A;  4DLO A; 
#chains in the Genus database with same CATH topology
 2JNC A;  3EHT A;  5II0 A;  3IOL A;  3N7R A;  2QKH A;  3EHU A;  4ERS A;  2JND A;  4LF3 C;  3C5T A;  3AQF B;  2XDG A;  1U34 A;  3C4M A;  3N7S A;  2JOD A;  4HJ0 A;  3EHS A;  3N7P A;  2L27 A;  4ZGM A;  3H3G A;  3C59 A;  3L2J A;  4DLQ A;  4DLO A; 
#chains in the Genus database with same CATH homology
 2JNC A;  3EHT A;  5II0 A;  3IOL A;  3N7R A;  2QKH A;  3EHU A;  4ERS A;  2JND A;  4LF3 C;  3C5T A;  3AQF B;  2XDG A;  1U34 A;  3C4M A;  3N7S A;  2JOD A;  4HJ0 A;  3EHS A;  3N7P A;  2L27 A;  4ZGM A;  3H3G A;  3C59 A;  3L2J A;  4DLQ A;  4DLO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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