4G03A

High-resolution crystal structural variance analysis between recombinant and wild-type human serum albumin
Total Genus 218
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
218
sequence length
578
structure length
578
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title High-resolution Crystal Structural Variance Analysis between Recombinant and Wild-type Human Serum Albumin
rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords Serum albumin
total genus 218
structure length 578
sequence length 578
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4g03A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4g03A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4g03A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4g03A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4g03A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4g03A05
3LU6A 4F5TA 5IJEA 4L9KA 2BXBA 1BKEA 3B9MA 1E7IA 2BXOA 2YDFA 5ID7A 4JK4A 4S1YA 2BXEA 1HK1A 2BX8A 2XVQA 2XW0A 4J2VA 3B9LA 3JRYA 4ZBRA 5IFOA 1AO6A 1BJ5A 2BXLA 1E7GA 4E99A 3LU7A 4LUHA 2BXDA 4IW2A 2BXIA 2VUEA 1E7FA 1N5UA 2BXHA 1KXPD 2BXNA 4LA0A 1HK3A 1E7BA 2XSIA 4F5VA 1E7AA 1GNJA 2BXQA 1BM0A 1E78A 4N0UD 2BXAA 5IIXA 4PO0A 3V09A 2BXFA 1TF0A 2BXPA 4LUFA 1E7CA 4G04A 3UIVA 1HK4A 5DQFA 3LU8A 4EMXA 2XVWA 1O9XA 3SQJA 4F5SA 4G03A 1E7EA 2VDBA 1HK2A 2BXGA 1HA2A 5IJFA 4K71A 3CX9A 2BXKA 4L8UA 1GNIA 4L9QA 5FUOA 1E7HA 1MA9A 4IW1A 4Z69A 4HGKA 2I30A 5HOZA 3TDLA 5IIHA 5IJ5A 5ID9A 1KW2A 2XW1A 4BKEA 4LB9A 2XVVA 3V03A 2BXMA 4K2CA 3V08A 1UORA 5DBYA 1HK5A 4N0FD 1LOTA 5GHKA 2BXCA 2VUFA 4OT2A 2I2ZA 5IIUA 1J78A 1J7EA 1H9ZA 4ZBQA 4F5UA 3A73A 2XVUA 4HGMB 4OR0A 4LB2A 3JQZA
chains in the Genus database with same CATH superfamily
2DYOA 4W4UB 2NNWA 3LU6A 4F5TA 5IJEA 4L9KA 2BXBA 3ECPA 2XMOA 1BKEA 3B9MA 1E7IA 1VFIA 2BXOA 2Z8JA 2DG5A 2YDFA 5ID7A 2OZBB 3FWBC 4GDKB 4N3ZA 3PLAA 3W1SA 3GQUA 4JK4A 4S1YA 3G9KD 2BXEA 4D7XA 1IJGA 1HK1A 2BX8A 2XVQA 2XW0A 3A75A 4J2VA 3WHRA 3B9LA 3JRYA 4ZBRA 5IFOA 3WHQA 1AO6A 4ZCGA 1BJ5A 4NAWB 1MIVA 2LXSA 2BXLA 1E7GA 4E99A 2QHBA 4BY9C 1MIYA 3LU7A 2EFDA 4LUHA 2BXDA 4IW2A 4OTTA 2LOQA 2LQHA 2BXIA 2VUEA 1E7FA 2EFHA 1N5UA 1TXUA 1MUSA 2BXHA 1KXPD 2BXNA 3WHSA 4LA0A 2NQOA 4TQ0A 1HK3A 1E7BA 4G01A 1FOUA 4ZUXV 3MHSB 2Z8KA 4FJCB 2XSIA 5B5TA 2ROHA 4F5VA 1E7AA 1GNJA 2BXQA 1BM0A 1E78A 4N0UD 2BXAA 3BPJA 5IIXA 4PO0A 3V09A 3SIVB 4GDXA 2BXFA 2Z8IA 2QMCA 1TF0A 2BXPA 4LUFA 1E7CA 4G04A 2CKXA 3UIVA 1HK4A 5DQFA 3LU8A 4EMXA 5GINA 5BPKA 2XVWA 4I9OA 1O9XA 3SQJA 4F5SA 4G03A 1E7EA 2VDBA 3FWCC 1HK2A 2AGHB 2DBXA 2DYMA 2K0NA 4ZC6A 3NVMA 2BXGA 2KBZA 4Z9OA 1HA2A 2QM6A 2LXTA 5IJFA 1KDXA 4K71A 1NT2B 2BXKA 3CX9A 3M99C 3ICXA 4L8UA 1GNIA 4L9QA 5FUOA 4GG2A 1MM8A 1E7HA 4WA6B 3KIKA 1MA9A 1H5WA 4IW1A 1MIWA 2E0YA 2KWFA 4Z69A 3KJLA 4HGKA 2EFEA 2I30A 2LQIA 5HOZA 3NMUA 3NVIA 3GA9L 2EFCA 4M70B 4TQ1A 3TDLA 5IIHA 5IJ5A 5ID9A 4C31B 1KW2A 2XW1A 4BKEA 2OT3A 2XVVA 4LB9A 3V03A 4MBEC 3MHHB 2BXMA 4K2CA 3V08A 2E0XA 2GUTA 3H37A 3VQIA 4DM0A 1UORA 5DBYA 2DBUA 2AJEA 1HK5A 4FIPB 4N0FD 3SIUB 5GIPA 1VZSA 3GQXA 1LOTA 5GHKA 2BXCA 2VUFA 1SB0A 4OT2A 2I2ZA 4FK5B 5IIUA 1LNSA 4GDLB 4ZBKA 5GIOA 1J78A 1J7EA 1H9ZA 3H3AA 4ZBQA 4F5UA 3A73A 1JNBA 2V36A 2XVUA 5D7GA 4OTUA 2JUHA 4HGMB 3NVKA 4OR0A 4LB2A 1MUHA 3JQZA 4DHXB 2DBWA 3FNMA
chains in the Genus database with same CATH topology
2DYOA 4W4UB 2NNWA 3LU6A 4F5TA 5IJEA 4L9KA 2BXBA 2XMOA 1BKEA 3B9MA 1E7IA 1VFIA 2BXOA 2Z8JA 2DG5A 2YDFA 5ID7A 2OZBB 3FWBC 4GDKB 4N3ZA 3PLAA 3W1SA 3GQUA 4JK4A 4S1YA 3G9KD 2BXEA 1IJGA 1HK1A 2BX8A 2XVQA 2XW0A 3A75A 4J2VA 3WHRA 3B9LA 3JRYA 4ZBRA 5IFOA 3WHQA 1AO6A 4ZCGA 1BJ5A 4NAWB 1MIVA 2BXLA 1E7GA 4E99A 2QHBA 4BY9C 1MIYA 3LU7A 2EFDA 4LUHA 2BXDA 4IW2A 4OTTA 2LOQA 2BXIA 2VUEA 1E7FA 2EFHA 1N5UA 1TXUA 2BXHA 1KXPD 2BXNA 3WHSA 4LA0A 2NQOA 4TQ0A 1HK3A 1E7BA 4G01A 1FOUA 4ZUXV 3MHSB 2Z8KA 4FJCB 2XSIA 5B5TA 2ROHA 4F5VA 1E7AA 1GNJA 2BXQA 1BM0A 1E78A 4N0UD 2BXAA 5IIXA 4PO0A 3V09A 3SIVB 4GDXA 2BXFA 2Z8IA 2QMCA 1TF0A 2BXPA 4LUFA 1E7CA 4G04A 2CKXA 3UIVA 1HK4A 5DQFA 3LU8A 4EMXA 5GINA 5BPKA 2XVWA 1O9XA 3SQJA 4F5SA 4G03A 1E7EA 2VDBA 3FWCC 1HK2A 2DYMA 2DBXA 4ZC6A 3NVMA 2BXGA 2KBZA 4Z9OA 1HA2A 2QM6A 5IJFA 4K71A 1NT2B 2BXKA 3CX9A 3M99C 3ICXA 4L8UA 1GNIA 4L9QA 5FUOA 4GG2A 1E7HA 4WA6B 3KIKA 1MA9A 1H5WA 4IW1A 1MIWA 2E0YA 4Z69A 3KJLA 4HGKA 2EFEA 2I30A 5HOZA 3NMUA 3NVIA 3GA9L 2EFCA 4M70B 4TQ1A 3TDLA 5IIHA 5IJ5A 5ID9A 4C31B 1KW2A 2XW1A 4BKEA 2OT3A 2XVVA 4LB9A 3V03A 4MBEC 3MHHB 2BXMA 4K2CA 3V08A 2E0XA 3VQIA 3H37A 1UORA 5DBYA 2DBUA 2AJEA 1HK5A 4FIPB 4N0FD 3SIUB 5GIPA 1VZSA 3GQXA 1LOTA 5GHKA 2BXCA 2VUFA 4OT2A 2I2ZA 4FK5B 5IIUA 1LNSA 4GDLB 4ZBKA 5GIOA 1J78A 1J7EA 1H9ZA 3H3AA 4ZBQA 4F5UA 3A73A 1JNBA 2V36A 2XVUA 5D7GA 4OTUA 2JUHA 4HGMB 3NVKA 4OR0A 4LB2A 3JQZA 4DHXB 2DBWA 3FNMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LU6 A;  4F5T A;  5IJE A;  4L9K A;  2BXB A;  1BKE A;  3B9M A;  1E7I A;  2BXO A;  2YDF A;  5ID7 A;  4JK4 A;  4S1Y A;  2BXE A;  1HK1 A;  2BX8 A;  2XVQ A;  2XW0 A;  4J2V A;  3B9L A;  3JRY A;  4ZBR A;  5IFO A;  1AO6 A;  1BJ5 A;  2BXL A;  1E7G A;  4E99 A;  3LU7 A;  4LUH A;  2BXD A;  4IW2 A;  2BXI A;  2VUE A;  1E7F A;  1N5U A;  2BXH A;  1KXP D;  2BXN A;  4LA0 A;  1HK3 A;  1E7B A;  2XSI A;  4F5V A;  1E7A A;  1GNJ A;  2BXQ A;  1BM0 A;  1E78 A;  4N0U D;  2BXA A;  5IIX A;  4PO0 A;  3V09 A;  2BXF A;  1TF0 A;  2BXP A;  4LUF A;  1E7C A;  4G04 A;  3UIV A;  1HK4 A;  5DQF A;  3LU8 A;  4EMX A;  2XVW A;  1O9X A;  3SQJ A;  4F5S A;  4G03 A;  1E7E A;  2VDB A;  1HK2 A;  2BXG A;  1HA2 A;  5IJF A;  4K71 A;  3CX9 A;  2BXK A;  4L8U A;  1GNI A;  4L9Q A;  5FUO A;  1E7H A;  1MA9 A;  4IW1 A;  4Z69 A;  4HGK A;  2I30 A;  5HOZ A;  3TDL A;  5IIH A;  5IJ5 A;  5ID9 A;  1KW2 A;  2XW1 A;  4BKE A;  4LB9 A;  2XVV A;  3V03 A;  2BXM A;  4K2C A;  3V08 A;  1UOR A;  5DBY A;  1HK5 A;  4N0F D;  1LOT A;  5GHK A;  2BXC A;  2VUF A;  4OT2 A;  2I2Z A;  5IIU A;  1J78 A;  1J7E A;  1H9Z A;  4ZBQ A;  4F5U A;  3A73 A;  2XVU A;  4HGM B;  4OR0 A;  4LB2 A;  3JQZ A; 
#chains in the Genus database with same CATH topology
 2DYO A;  4W4U B;  2NNW A;  3LU6 A;  4F5T A;  5IJE A;  4L9K A;  2BXB A;  3ECP A;  2XMO A;  1BKE A;  3B9M A;  1E7I A;  1VFI A;  2BXO A;  2Z8J A;  2DG5 A;  2YDF A;  5ID7 A;  2OZB B;  3FWB C;  4GDK B;  4N3Z A;  3PLA A;  3W1S A;  3GQU A;  4JK4 A;  4S1Y A;  3G9K D;  2BXE A;  4D7X A;  1IJG A;  1HK1 A;  2BX8 A;  2XVQ A;  2XW0 A;  3A75 A;  4J2V A;  3WHR A;  3B9L A;  3JRY A;  4ZBR A;  5IFO A;  3WHQ A;  1AO6 A;  4ZCG A;  1BJ5 A;  4NAW B;  1MIV A;  2LXS A;  2BXL A;  1E7G A;  4E99 A;  2QHB A;  4BY9 C;  1MIY A;  3LU7 A;  2EFD A;  4LUH A;  2BXD A;  4IW2 A;  4OTT A;  2LOQ A;  2LQH A;  2BXI A;  2VUE A;  1E7F A;  2EFH A;  1N5U A;  1TXU A;  1MUS A;  2BXH A;  1KXP D;  2BXN A;  3WHS A;  4LA0 A;  2NQO A;  4TQ0 A;  1HK3 A;  1E7B A;  4G01 A;  1FOU A;  4ZUX V;  3MHS B;  2Z8K A;  4FJC B;  2XSI A;  5B5T A;  2ROH A;  4F5V A;  1E7A A;  1GNJ A;  2BXQ A;  1BM0 A;  1E78 A;  4N0U D;  2BXA A;  3BPJ A;  5IIX A;  4PO0 A;  3V09 A;  3SIV B;  4GDX A;  2BXF A;  2Z8I A;  2QMC A;  1TF0 A;  2BXP A;  4LUF A;  1E7C A;  4G04 A;  2CKX A;  3UIV A;  1HK4 A;  5DQF A;  3LU8 A;  4EMX A;  5GIN A;  5BPK A;  2XVW A;  4I9O A;  1O9X A;  3SQJ A;  4F5S A;  4G03 A;  1E7E A;  2VDB A;  3FWC C;  1HK2 A;  2AGH B;  2DBX A;  2DYM A;  2K0N A;  4ZC6 A;  3NVM A;  2BXG A;  2KBZ A;  4Z9O A;  1HA2 A;  2QM6 A;  2LXT A;  5IJF A;  1KDX A;  4K71 A;  1NT2 B;  2BXK A;  3CX9 A;  3M99 C;  3ICX A;  4L8U A;  1GNI A;  4L9Q A;  5FUO A;  4GG2 A;  1MM8 A;  1E7H A;  4WA6 B;  3KIK A;  1MA9 A;  1H5W A;  4IW1 A;  1MIW A;  2E0Y A;  2KWF A;  4Z69 A;  3KJL A;  4HGK A;  2EFE A;  2I30 A;  2LQI A;  5HOZ A;  3NMU A;  3NVI A;  3GA9 L;  2EFC A;  4M70 B;  4TQ1 A;  3TDL A;  5IIH A;  5IJ5 A;  5ID9 A;  4C31 B;  1KW2 A;  2XW1 A;  4BKE A;  2OT3 A;  2XVV A;  4LB9 A;  3V03 A;  4MBE C;  3MHH B;  2BXM A;  4K2C A;  3V08 A;  2E0X A;  2GUT A;  3H37 A;  3VQI A;  4DM0 A;  1UOR A;  5DBY A;  2DBU A;  2AJE A;  1HK5 A;  4FIP B;  4N0F D;  3SIU B;  5GIP A;  1VZS A;  3GQX A;  1LOT A;  5GHK A;  2BXC A;  2VUF A;  1SB0 A;  4OT2 A;  2I2Z A;  4FK5 B;  5IIU A;  1LNS A;  4GDL B;  4ZBK A;  5GIO A;  1J78 A;  1J7E A;  1H9Z A;  3H3A A;  4ZBQ A;  4F5U A;  3A73 A;  1JNB A;  2V36 A;  2XVU A;  5D7G A;  4OTU A;  2JUH A;  4HGM B;  3NVK A;  4OR0 A;  4LB2 A;  1MUH A;  3JQZ A;  4DHX B;  2DBW A;  3FNM A; 
#chains in the Genus database with same CATH homology
 2DYO A;  4W4U B;  2NNW A;  3LU6 A;  4F5T A;  5IJE A;  4L9K A;  2BXB A;  2XMO A;  1BKE A;  3B9M A;  1E7I A;  1VFI A;  2BXO A;  2Z8J A;  2DG5 A;  2YDF A;  5ID7 A;  2OZB B;  3FWB C;  4GDK B;  4N3Z A;  3PLA A;  3W1S A;  3GQU A;  4JK4 A;  4S1Y A;  3G9K D;  2BXE A;  1IJG A;  1HK1 A;  2BX8 A;  2XVQ A;  2XW0 A;  3A75 A;  4J2V A;  3WHR A;  3B9L A;  3JRY A;  4ZBR A;  5IFO A;  3WHQ A;  1AO6 A;  4ZCG A;  1BJ5 A;  4NAW B;  1MIV A;  2BXL A;  1E7G A;  4E99 A;  2QHB A;  4BY9 C;  1MIY A;  3LU7 A;  2EFD A;  4LUH A;  2BXD A;  4IW2 A;  4OTT A;  2LOQ A;  2BXI A;  2VUE A;  1E7F A;  2EFH A;  1N5U A;  1TXU A;  2BXH A;  1KXP D;  2BXN A;  3WHS A;  4LA0 A;  2NQO A;  4TQ0 A;  1HK3 A;  1E7B A;  4G01 A;  1FOU A;  4ZUX V;  3MHS B;  2Z8K A;  4FJC B;  2XSI A;  5B5T A;  2ROH A;  4F5V A;  1E7A A;  1GNJ A;  2BXQ A;  1BM0 A;  1E78 A;  4N0U D;  2BXA A;  5IIX A;  4PO0 A;  3V09 A;  3SIV B;  4GDX A;  2BXF A;  2Z8I A;  2QMC A;  1TF0 A;  2BXP A;  4LUF A;  1E7C A;  4G04 A;  2CKX A;  3UIV A;  1HK4 A;  5DQF A;  3LU8 A;  4EMX A;  5GIN A;  5BPK A;  2XVW A;  1O9X A;  3SQJ A;  4F5S A;  4G03 A;  1E7E A;  2VDB A;  3FWC C;  1HK2 A;  2DYM A;  2DBX A;  4ZC6 A;  3NVM A;  2BXG A;  2KBZ A;  4Z9O A;  1HA2 A;  2QM6 A;  5IJF A;  4K71 A;  1NT2 B;  2BXK A;  3CX9 A;  3M99 C;  3ICX A;  4L8U A;  1GNI A;  4L9Q A;  5FUO A;  4GG2 A;  1E7H A;  4WA6 B;  3KIK A;  1MA9 A;  1H5W A;  4IW1 A;  1MIW A;  2E0Y A;  4Z69 A;  3KJL A;  4HGK A;  2EFE A;  2I30 A;  5HOZ A;  3NMU A;  3NVI A;  3GA9 L;  2EFC A;  4M70 B;  4TQ1 A;  3TDL A;  5IIH A;  5IJ5 A;  5ID9 A;  4C31 B;  1KW2 A;  2XW1 A;  4BKE A;  2OT3 A;  2XVV A;  4LB9 A;  3V03 A;  4MBE C;  3MHH B;  2BXM A;  4K2C A;  3V08 A;  2E0X A;  3VQI A;  3H37 A;  1UOR A;  5DBY A;  2DBU A;  2AJE A;  1HK5 A;  4FIP B;  4N0F D;  3SIU B;  5GIP A;  1VZS A;  3GQX A;  1LOT A;  5GHK A;  2BXC A;  2VUF A;  4OT2 A;  2I2Z A;  4FK5 B;  5IIU A;  1LNS A;  4GDL B;  4ZBK A;  5GIO A;  1J78 A;  1J7E A;  1H9Z A;  3H3A A;  4ZBQ A;  4F5U A;  3A73 A;  1JNB A;  2V36 A;  2XVU A;  5D7G A;  4OTU A;  2JUH A;  4HGM B;  3NVK A;  4OR0 A;  4LB2 A;  3JQZ A;  4DHX B;  2DBW A;  3FNM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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