4HAUB

Crystal structure of crm1 inhibitor ratjadone a in complex with crm1-ran-ranbp1
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
121
structure length
121
Chain Sequence
EEDEEVLYKVRAKLFRFDKDAKEWKERGTGDCKFLKNKKTNKVRILMRRDKTLKICANHIIAPEYTLKPNVGSDRSWVYACTADIAEGEAEAFTFAIRFGSKENADKFKEEFEKAQEINKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
pubmed doi rcsb
molecule tags Protein transport/antibiotic
source organism Homo sapiens
molecule keywords GTP-binding nuclear protein Ran
total genus 37
structure length 121
sequence length 121
ec nomenclature
pdb deposition date 2012-09-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00638 Ran_BP1 RanBP1 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 4hauB00
2LKOA 2DX5A 4HB3B 4HAWB 5HE1A 2VKIA 1P3RA 3GYOA 3PP2A 5J3QA 2ROZB 2K00A 2M14A 2R0DA 1UNPA 2CY4A 2YS3A 1M7EA 3CIKA 2L2IA 2Z0OA 2YSZA 4DX8A 3DXDA 2LG1A 3QIJA 2YRYA 2YF0A 2EMSA 3ODWA 4GXBA 3F5RA 3P7ZA 2VRWB 2RVBB 1V5UA 2DYNA 2J0KA 4A6FA 1M7RA 1U5EA 3PVUA 2DA0A 4D0NB 2I1JA 3KSYA 1KZ7A 2H7EA 1MK9B 1V89A 4K17A 2N0YA 5D3XA 2P8VA 1MIZB 3P6AA 4HB4B 1SGHA 3ZVRA 3TCAA 4ZRJA 2MWNB 4ZRKA 1V61A 3FEHA 2I1KA 1FHWA 2GCJA 3DXCA 3U8ZA 1Q67A 2GCLA 2IFSA 3BINA 1FB8A 5HE0A 3KRWA 2Q13A 2OTXA 3SO6A 1AQCA 1WJ1A 2DKQA 4H8SA 4HDQA 4F7HA 2Z0PA 1EAZA 2CODA 3TFMA 3IVFA 2IYBA 3PEGA 2R09A 4F7UP 2D9ZA 1PMSA 4MK0A 1NI2A 1EGXA 1QC6A 2Y8GA 1K5DB 2COCA 2DLWA 5JLJB 1DDVA 2DHKA 2LOXA 1WGUA 1KI1B 1H10A 3GYPA 5DHFB 4HAZB 1P5TA 1WVHA 3X23A 1B55A 1OY2A 1PLSA 1NTVA 2FJLA 2YVCA 2D2QA 3PSCA 1U2BA 2P0HA 3MPXA 2W2XD 3VIAA 3CXBB 1FAOA 5DH9B 2J59M 1KZGA 3ML4A 2DFKA 3PG7A 5D3YA 3U7DA 1LW3A 1DROA 4HB2B 1TQZA 1X05A 2COAA 1GG3A 2W2WA 2AEHA 3SUZA 1GC7A 4YONA 3KY9A 4CHMA 2RSGA 3D8EA 2YS5A 3FM8C 5C5BA 2M38A 4A6FB 1E5WA 4A6KA 1UPQA 4TKNA 2L1CA 2D9VA 5JP4A 1V88A 5FI1A 3OANA 2DTCA 2V76A 2NMBA 4KHOA 5CLLB 1EF1A 1MKEA 4MY6A 2D10A 2MKRA 2CAYA 4CHJA 3PVLA 4HAXB 3M1IB 2P0FA 1BWNA 2X18A 2CRFA 1N3HA 5LONB 5KQ4A 2HE7A 2H7DA 4IOYX 4K2OA 3O96A 4KHAA 3KRXA 2YS1A 4A6HA 4Y94A 1TJ6A 4WJ7A 2BCJA 1FOEA 2UZSA 3VOQA 4KHBB 3UZTA 3RCPA 1J0WA 1DYNA 1NTYA 4EJNA 3TW1A 2VSZA 1MIXA 3A8QA 4KAXB 1BTKA 2LOZA 3ULCA 3BJIA 1RJ2A 1XD4A 2CY5A 1Y19B 1WGQA 2JP2A 3AJ4A 1GC6A 4GMXB 1P6SA 1V5PA 1FGZA 2DYQA 4KVGB 1BAKA 4DBBA 1X86A 1XX0A 2MFQA 3HQCA 4F7GA 1UNRA 1W1HA 2I5FA 3PVWA 3A98B 4DX90 1FHOA 1U29A 5EFXA 2HTHB 3A8PA 3KZ1A 1XCGA 2EJ8A 4YL8A 1WG7A 5HE2A 1RRPB 1DBHA 1FGYA 1BTNA 4P7IA 2W2XC 4GPTB 3QWMA 2J0JA 5D3WA 4EKUA 3WYFB 5C16A 5JHHA 3PZDA 3T06A 1UNQA 2ZPYA 3SNHA 4BBKA 5HE3A 4HAYB 2D4QA 2ADZA 2Z0QA 1U27A 1ZC4B 2QKLA 1XKEA 2YT0A 2DKPA 5C5BB 5D27A 2QKMA 4GN1A 1ISNA 4Z2NA 1I2HA 3V5WA 4A5KA 1XR0B 3ODXA 3AU5A 2YT1A 3N7CA 2D9YA 5CLQB 2NZ8B 5JHGA 2EC1A 2N23A 2OQBA 5D3VA 1U5FA 1MAIA 1DDWA 2P0DA 3FSSA 4HAVB 3TVVA 2DN6A 2DX1A 2J0MA 2ELAA 4B6HA 4DXAB 2RNRB 2ELBA 4MT7A 2PZ1A 3ZDTA 2LULA 3HW2B 1OMWA 5LOPB 3AU4A 4HATB 2EMTA 1DDMA 1Z87A 4WSFA 3WA0A 4L6EA 4XWXA 5KCVA 1TXDA 5KQ1A 1WJMA 4HAUB 4HHVA 1AWEA 1X1FA 5DHAB 2ROVA 4Z2MB 1H4RA 3HK0A 4K2PA 4NSWA 4IAPA 4C0AA 1IRSA 1ZM0A 1MK7B 1W1DA 2RLOA 3ULBA 1J19A 2D9WA 2LYDA 4IFSA 3TO1A 5C79A 2Y8FA 1I7AA 1EVHA 3LJUX 5J3TA 2Y7BA 3D8DA 2KGXB 1FHXA 3SV1A 1OQNA 1PFJA 2GS0A 3SYXA 2G35A 2KCJA 2AL6A 2XQNM 3NSUA 1U5DA 4HB0B 2E2XA 1SHCA 3DXEA 5J3YA 4GMVA 2K2UA 1XODA 2UZRA 1U5GA 3G9WA 1W1GA 1MPHA 2KUPA 4PQ0A 4EMOA 5DI9B 1QQGA 1K5GB 2K2JA 2RUKB 1ZVRA 2COFA 1WI1A 1ZC3B 1UEFA 5L81A 5FI0A 1ZSQA 3F0WA 2D9XA 2D11A 1LB1A 3D8FA 1V5MA 5C6RA 2GJYA 4NY0A 3ODOA 1Y5OA 1X11A 4WVFB 2UVMA 2DHJA 2MDXA 2RGNB 2I5CA 3MDBC 4ZRIA 4TYZA 4GZUA 1X1GA 1UPRA 1NU2A 4PNKA 5GOWB 4CYEA 3QBVB 4K81A 4HDOA 2DHIA 5DIFB
chains in the Genus database with same CATH superfamily
2LKOA 2DX5A 4HB3B 4HAWB 5HE1A 2VKIA 1P3RA 3GYOA 3PP2A 5J3QA 2R2YA 2ROZB 2Z4DA 2K00A 2M14A 2R0DA 1UNPA 2CY4A 2YS3A 1M7EA 3CIKA 2L2IA 2Z0OA 2YSZA 4DX8A 3DXDA 3HIEA 2LG1A 3QIJA 2YRYA 2YF0A 2EMSA 3ODWA 4GXBA 3F5RA 3P7ZA 2VRWB 2RVBB 1V5UA 2DYNA 2J0KA 4A6FA 1M7RA 1U5EA 3PVUA 2DA0A 4D0NB 2I1JA 3KSYA 1KZ7A 2H7EA 1MK9B 1V89A 4K17A 2N0YA 5D3XA 3NW8A 2P8VA 1MIZB 3P6AA 4HB4B 1SGHA 3ZVRA 3TCAA 4ZRJA 2MWNB 4ZRKA 1V61A 3FEHA 2I1KA 1FHWA 2GCJA 3DXCA 3U8ZA 1Q67A 2GCLA 2IFSA 3BINA 1FB8A 5HE0A 3KRWA 2Q13A 2OTXA 3SO6A 1AQCA 1WJ1A 2DKQA 4H8SA 4HDQA 4F7HA 2Z0PA 1EAZA 2CODA 3TFMA 3IVFA 2IYBA 3PEGA 4KHBA 2R09A 4F7UP 2D9ZA 1PMSA 4QJ4B 4MK0A 1NI2A 1EGXA 1QC6A 2Y8GA 1K5DB 2COCA 2DLWA 5JLJB 1DDVA 2DHKA 2LOXA 1WGUA 1KI1B 1H10A 2Z13A 3GYPA 5DHFB 4HAZB 1P5TA 1WVHA 3X23A 1B55A 1OY2A 1PLSA 1NTVA 2FJLA 2YVCA 2D2QA 3PSCA 3U12A 1U2BA 2P0HA 3MPXA 2W2XD 3VIAA 3CXBB 1FAOA 5DH9B 2J59M 1KZGA 3ML4A 2DFKA 5I2SA 3PG7A 5D3YA 3U7DA 1LW3A 1DROA 4HB2B 1TQZA 1X05A 2COAA 1GG3A 2W2WA 2AEHA 4GNKB 3SUZA 1GC7A 4YONA 3KY9A 2YT2A 4CHMA 2RSGA 3D8EA 2YS5A 3FM8C 3NWAA 5C5BA 2M38A 4A6FB 1E5WA 4A6KA 1UPQA 4TKNA 2L1CA 2D9VA 5JP4A 1V88A 5FI1A 3OANA 2DTCA 4OT1A 2V76A 2NMBA 4KHOA 5CLLB 1EF1A 1MKEA 4MY6A 2D10A 2MKRA 2CAYA 4CHJA 3PVLA 2GUMA 4HAXB 3M1IB 2P0FA 1BWNA 2X18A 2CRFA 1N3HA 5LONB 5KQ4A 2HE7A 2H7DA 4IOYX 4K2OA 3O96A 4KHAA 3DCXA 3KRXA 2YS1A 3HSAA 4A6HA 4Y94A 1TJ6A 2RRFA 4WJ7A 2BCJA 1FOEA 2UZSA 3VOQA 4D6WA 4KHBB 3UZTA 2KUQA 3RCPA 1J0WA 1DYNA 1NTYA 4EJNA 3TW1A 2VSZA 1MIXA 3A8QA 4KAXB 1BTKA 2LOZA 3ULCA 3BJIA 1RJ2A 1XD4A 2CY5A 1Y19B 1WGQA 2JP2A 3AJ4A 1GC6A 3A58A 1P6SA 1V5PA 1FGZA 2DYQA 4GMXB 4KVGB 4DBBA 1BAKA 1X86A 1XX0A 2MFQA 3HQCA 4F7GA 1UNRA 1W1HA 2I5FA 3PVWA 3NWFA 3A98B 4DX90 1FHOA 1U29A 5EFXA 2KIGA 2HTHB 3A8PA 3KZ1A 1XCGA 4CSQA 2EJ8A 4YL8A 1WG7A 5HE2A 1RRPB 1DBHA 1FGYA 1BTNA 4QJ5B 4P7IA 1T77A 2W2XC 4GPTB 3QWMA 2J0JA 5D3WA 4EKUA 3WYFB 5C16A 5JHHA 3PZDA 3T06A 1UNQA 2ZPYA 3SNHA 4BBKA 5HE3A 4HAYB 2D4QA 2ADZA 2Z0QA 1U27A 1ZC4B 2QKLA 1XKEA 2YT0A 2DKPA 5IRSA 2FJUB 5C5BB 5D27A 2NBVA 2QKMA 4GN1A 1ISNA 4QXAB 4Z2NA 1I2HA 3V5WA 4A5KA 1XR0B 2KIEA 3ODXA 3AU5A 2YT1A 3N7CA 2D9YA 5CLQB 2NZ8B 5JHGA 2EC1A 2N23A 2OQBA 5D3VA 1U5FA 1MAIA 1DDWA 2P0DA 4HSIA 3FSSA 4HAVB 3TVVA 2DN6A 2DX1A 2J0MA 2ELAA 2Z14A 4B6HA 4DXAB 2RNRB 2K49A 2ELBA 4MT7A 2Z59A 2PZ1A 3ZDTA 2LULA 3NWDA 3HW2B 1OMWA 5LOPB 3AU4A 4QJ3B 4HATB 2EMTA 1DDMA 1Z87A 4WSFA 3WA0A 4L6EA 4XWXA 5KCVA 1TXDA 5KQ1A 2K8EA 1WJMA 4HAUB 3B77A 1MI1A 4HHVA 1AWEA 1X1FA 5DHAB 2ROVA 4Z2MB 1H4RA 3HK0A 4K2PA 4NSWA 4IAPA 4C0AA 1IRSA 1ZM0A 1MK7B 1W1DA 2RLOA 3ULBA 1J19A 2D9WA 3FVCA 4DIXA 2LYDA 4IFSA 3TO1A 5C79A 2Y8FA 1I7AA 1EVHA 3LJUX 5J3TA 2Y7BA 3D8DA 2KGXB 1FHXA 3SV1A 1OQNA 1PFJA 2GS0A 3SYXA 4L1RA 2G35A 2KCJA 2AL6A 2XQNM 3NSUA 1U5DA 4HB0B 2E2XA 1SHCA 3DXEA 5J3YA 4GMVA 5M4YB 2K2UA 1XODA 2UZRA 1U5GA 3G9WA 1W1GA 1ZYIA 1MPHA 2KUPA 4PQ0A 4EMOA 5DI9B 1QQGA 1K5GB 2K2JA 2RUKB 1ZVRA 2COFA 4GOUA 1WI1A 1ZC3B 3OHMB 1UEFA 5L81A 5FI0A 1ZSQA 3F0WA 2D9XA 2D11A 4OSNA 1LB1A 3D8FA 1V5MA 2KR0A 2ZKMX 5C6RA 2GJYA 4NY0A 3ODOA 1Y5OA 1X11A 4WVFB 2UVMA 2DHJA 2MDXA 2RGNB 2I5CA 3MDBC 4ZRIA 4TYZA 4GZUA 1X1GA 1UPRA 1NU2A 4PNKA 5I2MA 5GOWB 4CYEA 5LG4B 3QBVB 4K81A 4HDOA 2DHIA 5DIFB
chains in the Genus database with same CATH topology
2LKOA 2DX5A 4HB3B 4HAWB 5HE1A 2VKIA 1P3RA 3GYOA 3PP2A 5J3QA 2ROZB 2K00A 2M14A 2R0DA 1UNPA 2CY4A 2YS3A 1M7EA 3CIKA 2L2IA 2Z0OA 2YSZA 4DX8A 3DXDA 2LG1A 3QIJA 2YRYA 2YF0A 2EMSA 3ODWA 4GXBA 3F5RA 3P7ZA 2VRWB 2RVBB 1V5UA 2DYNA 2J0KA 4A6FA 1M7RA 1U5EA 3PVUA 2DA0A 4D0NB 2I1JA 3KSYA 1KZ7A 2H7EA 1MK9B 1V89A 4K17A 2N0YA 5D3XA 2P8VA 1MIZB 3P6AA 4HB4B 1SGHA 3ZVRA 3TCAA 4ZRJA 2MWNB 4ZRKA 1V61A 3FEHA 2I1KA 1FHWA 2GCJA 3DXCA 3U8ZA 1Q67A 2GCLA 2IFSA 3BINA 1FB8A 5HE0A 3KRWA 2Q13A 2OTXA 3SO6A 1AQCA 1WJ1A 2DKQA 4H8SA 4HDQA 4F7HA 2Z0PA 1EAZA 2CODA 3TFMA 3IVFA 2IYBA 3PEGA 2R09A 4F7UP 2D9ZA 1PMSA 4MK0A 1NI2A 1EGXA 1QC6A 2Y8GA 1K5DB 2COCA 2DLWA 5JLJB 1DDVA 2DHKA 2LOXA 1WGUA 1KI1B 1H10A 3GYPA 5DHFB 4HAZB 1P5TA 1WVHA 3X23A 1B55A 1OY2A 1PLSA 1NTVA 2FJLA 2YVCA 2D2QA 3PSCA 1U2BA 2P0HA 3MPXA 2W2XD 3VIAA 3CXBB 1FAOA 5DH9B 2J59M 1KZGA 3ML4A 2DFKA 3PG7A 5D3YA 3U7DA 1LW3A 1DROA 4HB2B 1TQZA 1X05A 2COAA 1GG3A 2W2WA 2AEHA 3SUZA 1GC7A 4YONA 3KY9A 4CHMA 2RSGA 3D8EA 2YS5A 3FM8C 5C5BA 2M38A 4A6FB 1E5WA 4A6KA 1UPQA 4TKNA 2L1CA 2D9VA 5JP4A 1V88A 5FI1A 3OANA 2DTCA 2V76A 2NMBA 4KHOA 5CLLB 1EF1A 1MKEA 4MY6A 2D10A 2MKRA 2CAYA 4CHJA 3PVLA 4HAXB 3M1IB 2P0FA 1BWNA 2X18A 2CRFA 1N3HA 5LONB 5KQ4A 2HE7A 2H7DA 4IOYX 4K2OA 3O96A 4KHAA 3KRXA 2YS1A 4A6HA 4Y94A 1TJ6A 4WJ7A 2BCJA 1FOEA 2UZSA 3VOQA 4KHBB 3UZTA 3RCPA 1J0WA 1DYNA 1NTYA 4EJNA 3TW1A 2VSZA 1MIXA 3A8QA 4KAXB 1BTKA 2LOZA 3ULCA 3BJIA 1RJ2A 1XD4A 2CY5A 1Y19B 1WGQA 2JP2A 3AJ4A 1GC6A 4GMXB 1P6SA 1V5PA 1FGZA 2DYQA 4KVGB 1BAKA 4DBBA 1X86A 1XX0A 2MFQA 3HQCA 4F7GA 1UNRA 1W1HA 2I5FA 3PVWA 3A98B 4DX90 1FHOA 1U29A 5EFXA 2HTHB 3A8PA 3KZ1A 1XCGA 2EJ8A 4YL8A 1WG7A 5HE2A 1RRPB 1DBHA 1FGYA 1BTNA 4P7IA 2W2XC 4GPTB 3QWMA 2J0JA 5D3WA 4EKUA 3WYFB 5C16A 5JHHA 3PZDA 3T06A 1UNQA 2ZPYA 3SNHA 4BBKA 5HE3A 4HAYB 2D4QA 2ADZA 2Z0QA 1U27A 1ZC4B 2QKLA 1XKEA 2YT0A 2DKPA 5C5BB 5D27A 2QKMA 4GN1A 1ISNA 4Z2NA 1I2HA 3V5WA 4A5KA 1XR0B 3ODXA 3AU5A 2YT1A 3N7CA 2D9YA 5CLQB 2NZ8B 5JHGA 2EC1A 2N23A 2OQBA 5D3VA 1U5FA 1MAIA 1DDWA 2P0DA 3FSSA 4HAVB 3TVVA 2DN6A 2DX1A 2J0MA 2ELAA 4B6HA 4DXAB 2RNRB 2ELBA 4MT7A 2PZ1A 3ZDTA 2LULA 3HW2B 1OMWA 5LOPB 3AU4A 4HATB 2EMTA 1DDMA 1Z87A 4WSFA 3WA0A 4L6EA 4XWXA 5KCVA 1TXDA 5KQ1A 1WJMA 4HAUB 4HHVA 1AWEA 1X1FA 5DHAB 2ROVA 4Z2MB 1H4RA 3HK0A 4K2PA 4NSWA 4IAPA 4C0AA 1IRSA 1ZM0A 1MK7B 1W1DA 2RLOA 3ULBA 1J19A 2D9WA 2LYDA 4IFSA 3TO1A 5C79A 2Y8FA 1I7AA 1EVHA 3LJUX 5J3TA 2Y7BA 3D8DA 2KGXB 1FHXA 3SV1A 1OQNA 1PFJA 2GS0A 3SYXA 2G35A 2KCJA 2AL6A 2XQNM 3NSUA 1U5DA 4HB0B 2E2XA 1SHCA 3DXEA 5J3YA 4GMVA 2K2UA 1XODA 2UZRA 1U5GA 3G9WA 1W1GA 1MPHA 2KUPA 4PQ0A 4EMOA 5DI9B 1QQGA 1K5GB 2K2JA 2RUKB 1ZVRA 2COFA 1WI1A 1ZC3B 1UEFA 5L81A 5FI0A 1ZSQA 3F0WA 2D9XA 2D11A 1LB1A 3D8FA 1V5MA 5C6RA 2GJYA 4NY0A 3ODOA 1Y5OA 1X11A 4WVFB 2UVMA 2DHJA 2MDXA 2RGNB 2I5CA 3MDBC 4ZRIA 4TYZA 4GZUA 1X1GA 1UPRA 1NU2A 4PNKA 5GOWB 4CYEA 3QBVB 4K81A 4HDOA 2DHIA 5DIFB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LKO A;  2DX5 A;  4HB3 B;  4HAW B;  5HE1 A;  2VKI A;  1P3R A;  3GYO A;  3PP2 A;  5J3Q A;  2ROZ B;  2K00 A;  2M14 A;  2R0D A;  1UNP A;  2CY4 A;  2YS3 A;  1M7E A;  3CIK A;  2L2I A;  2Z0O A;  2YSZ A;  4DX8 A;  3DXD A;  2LG1 A;  3QIJ A;  2YRY A;  2YF0 A;  2EMS A;  3ODW A;  4GXB A;  3F5R A;  3P7Z A;  2VRW B;  2RVB B;  1V5U A;  2DYN A;  2J0K A;  4A6F A;  1M7R A;  1U5E A;  3PVU A;  2DA0 A;  4D0N B;  2I1J A;  3KSY A;  1KZ7 A;  2H7E A;  1MK9 B;  1V89 A;  4K17 A;  2N0Y A;  5D3X A;  2P8V A;  1MIZ B;  3P6A A;  4HB4 B;  1SGH A;  3ZVR A;  3TCA A;  4ZRJ A;  2MWN B;  4ZRK A;  1V61 A;  3FEH A;  2I1K A;  1FHW A;  2GCJ A;  3DXC A;  3U8Z A;  1Q67 A;  2GCL A;  2IFS A;  3BIN A;  1FB8 A;  5HE0 A;  3KRW A;  2Q13 A;  2OTX A;  3SO6 A;  1AQC A;  1WJ1 A;  2DKQ A;  4H8S A;  4HDQ A;  4F7H A;  2Z0P A;  1EAZ A;  2COD A;  3TFM A;  3IVF A;  2IYB A;  3PEG A;  2R09 A;  4F7U P;  2D9Z A;  1PMS A;  4MK0 A;  1NI2 A;  1EGX A;  1QC6 A;  2Y8G A;  1K5D B;  2COC A;  2DLW A;  5JLJ B;  1DDV A;  2DHK A;  2LOX A;  1WGU A;  1KI1 B;  1H10 A;  3GYP A;  5DHF B;  4HAZ B;  1P5T A;  1WVH A;  3X23 A;  1B55 A;  1OY2 A;  1PLS A;  1NTV A;  2FJL A;  2YVC A;  2D2Q A;  3PSC A;  1U2B A;  2P0H A;  3MPX A;  2W2X D;  3VIA A;  3CXB B;  1FAO A;  5DH9 B;  2J59 M;  1KZG A;  3ML4 A;  2DFK A;  3PG7 A;  5D3Y A;  3U7D A;  1LW3 A;  1DRO A;  4HB2 B;  1TQZ A;  1X05 A;  2COA A;  1GG3 A;  2W2W A;  2AEH A;  3SUZ A;  1GC7 A;  4YON A;  3KY9 A;  4CHM A;  2RSG A;  3D8E A;  2YS5 A;  3FM8 C;  5C5B A;  2M38 A;  4A6F B;  1E5W A;  4A6K A;  1UPQ A;  4TKN A;  2L1C A;  2D9V A;  5JP4 A;  1V88 A;  5FI1 A;  3OAN A;  2DTC A;  2V76 A;  2NMB A;  4KHO A;  5CLL B;  1EF1 A;  1MKE A;  4MY6 A;  2D10 A;  2MKR A;  2CAY A;  4CHJ A;  3PVL A;  4HAX B;  3M1I B;  2P0F A;  1BWN A;  2X18 A;  2CRF A;  1N3H A;  5LON B;  5KQ4 A;  2HE7 A;  2H7D A;  4IOY X;  4K2O A;  3O96 A;  4KHA A;  3KRX A;  2YS1 A;  4A6H A;  4Y94 A;  1TJ6 A;  4WJ7 A;  2BCJ A;  1FOE A;  2UZS A;  3VOQ A;  4KHB B;  3UZT A;  3RCP A;  1J0W A;  1DYN A;  1NTY A;  4EJN A;  3TW1 A;  2VSZ A;  1MIX A;  3A8Q A;  4KAX B;  1BTK A;  2LOZ A;  3ULC A;  3BJI A;  1RJ2 A;  1XD4 A;  2CY5 A;  1Y19 B;  1WGQ A;  2JP2 A;  3AJ4 A;  1GC6 A;  4GMX B;  1P6S A;  1V5P A;  1FGZ A;  2DYQ A;  4KVG B;  1BAK A;  4DBB A;  1X86 A;  1XX0 A;  2MFQ A;  3HQC A;  4F7G A;  1UNR A;  1W1H A;  2I5F A;  3PVW A;  3A98 B;  4DX9 0;  1FHO A;  1U29 A;  5EFX A;  2HTH B;  3A8P A;  3KZ1 A;  1XCG A;  2EJ8 A;  4YL8 A;  1WG7 A;  5HE2 A;  1RRP B;  1DBH A;  1FGY A;  1BTN A;  4P7I A;  2W2X C;  4GPT B;  3QWM A;  2J0J A;  5D3W A;  4EKU A;  3WYF B;  5C16 A;  5JHH A;  3PZD A;  3T06 A;  1UNQ A;  2ZPY A;  3SNH A;  4BBK A;  5HE3 A;  4HAY B;  2D4Q A;  2ADZ A;  2Z0Q A;  1U27 A;  1ZC4 B;  2QKL A;  1XKE A;  2YT0 A;  2DKP A;  5C5B B;  5D27 A;  2QKM A;  4GN1 A;  1ISN A;  4Z2N A;  1I2H A;  3V5W A;  4A5K A;  1XR0 B;  3ODX A;  3AU5 A;  2YT1 A;  3N7C A;  2D9Y A;  5CLQ B;  2NZ8 B;  5JHG A;  2EC1 A;  2N23 A;  2OQB A;  5D3V A;  1U5F A;  1MAI A;  1DDW A;  2P0D A;  3FSS A;  4HAV B;  3TVV A;  2DN6 A;  2DX1 A;  2J0M A;  2ELA A;  4B6H A;  4DXA B;  2RNR B;  2ELB A;  4MT7 A;  2PZ1 A;  3ZDT A;  2LUL A;  3HW2 B;  1OMW A;  5LOP B;  3AU4 A;  4HAT B;  2EMT A;  1DDM A;  1Z87 A;  4WSF A;  3WA0 A;  4L6E A;  4XWX A;  5KCV A;  1TXD A;  5KQ1 A;  1WJM A;  4HAU B;  4HHV A;  1AWE A;  1X1F A;  5DHA B;  2ROV A;  4Z2M B;  1H4R A;  3HK0 A;  4K2P A;  4NSW A;  4IAP A;  4C0A A;  1IRS A;  1ZM0 A;  1MK7 B;  1W1D A;  2RLO A;  3ULB A;  1J19 A;  2D9W A;  2LYD A;  4IFS A;  3TO1 A;  5C79 A;  2Y8F A;  1I7A A;  1EVH A;  3LJU X;  5J3T A;  2Y7B A;  3D8D A;  2KGX B;  1FHX A;  3SV1 A;  1OQN A;  1PFJ A;  2GS0 A;  3SYX A;  2G35 A;  2KCJ A;  2AL6 A;  2XQN M;  3NSU A;  1U5D A;  4HB0 B;  2E2X A;  1SHC A;  3DXE A;  5J3Y A;  4GMV A;  2K2U A;  1XOD A;  2UZR A;  1U5G A;  3G9W A;  1W1G A;  1MPH A;  2KUP A;  4PQ0 A;  4EMO A;  5DI9 B;  1QQG A;  1K5G B;  2K2J A;  2RUK B;  1ZVR A;  2COF A;  1WI1 A;  1ZC3 B;  1UEF A;  5L81 A;  5FI0 A;  1ZSQ A;  3F0W A;  2D9X A;  2D11 A;  1LB1 A;  3D8F A;  1V5M A;  5C6R A;  2GJY A;  4NY0 A;  3ODO A;  1Y5O A;  1X11 A;  4WVF B;  2UVM A;  2DHJ A;  2MDX A;  2RGN B;  2I5C A;  3MDB C;  4ZRI A;  4TYZ A;  4GZU A;  1X1G A;  1UPR A;  1NU2 A;  4PNK A;  5GOW B;  4CYE A;  3QBV B;  4K81 A;  4HDO A;  2DHI A;  5DIF B; 
#chains in the Genus database with same CATH topology
 2LKO A;  2DX5 A;  4HB3 B;  4HAW B;  5HE1 A;  2VKI A;  1P3R A;  3GYO A;  3PP2 A;  5J3Q A;  2R2Y A;  2ROZ B;  2Z4D A;  2K00 A;  2M14 A;  2R0D A;  1UNP A;  2CY4 A;  2YS3 A;  1M7E A;  3CIK A;  2L2I A;  2Z0O A;  2YSZ A;  4DX8 A;  3DXD A;  3HIE A;  2LG1 A;  3QIJ A;  2YRY A;  2YF0 A;  2EMS A;  3ODW A;  4GXB A;  3F5R A;  3P7Z A;  2VRW B;  2RVB B;  1V5U A;  2DYN A;  2J0K A;  4A6F A;  1M7R A;  1U5E A;  3PVU A;  2DA0 A;  4D0N B;  2I1J A;  3KSY A;  1KZ7 A;  2H7E A;  1MK9 B;  1V89 A;  4K17 A;  2N0Y A;  5D3X A;  3NW8 A;  2P8V A;  1MIZ B;  3P6A A;  4HB4 B;  1SGH A;  3ZVR A;  3TCA A;  4ZRJ A;  2MWN B;  4ZRK A;  1V61 A;  3FEH A;  2I1K A;  1FHW A;  2GCJ A;  3DXC A;  3U8Z A;  1Q67 A;  2GCL A;  2IFS A;  3BIN A;  1FB8 A;  5HE0 A;  3KRW A;  2Q13 A;  2OTX A;  3SO6 A;  1AQC A;  1WJ1 A;  2DKQ A;  4H8S A;  4HDQ A;  4F7H A;  2Z0P A;  1EAZ A;  2COD A;  3TFM A;  3IVF A;  2IYB A;  3PEG A;  4KHB A;  2R09 A;  4F7U P;  2D9Z A;  1PMS A;  4QJ4 B;  4MK0 A;  1NI2 A;  1EGX A;  1QC6 A;  2Y8G A;  1K5D B;  2COC A;  2DLW A;  5JLJ B;  1DDV A;  2DHK A;  2LOX A;  1WGU A;  1KI1 B;  1H10 A;  2Z13 A;  3GYP A;  5DHF B;  4HAZ B;  1P5T A;  1WVH A;  3X23 A;  1B55 A;  1OY2 A;  1PLS A;  1NTV A;  2FJL A;  2YVC A;  2D2Q A;  3PSC A;  3U12 A;  1U2B A;  2P0H A;  3MPX A;  2W2X D;  3VIA A;  3CXB B;  1FAO A;  5DH9 B;  2J59 M;  1KZG A;  3ML4 A;  2DFK A;  5I2S A;  3PG7 A;  5D3Y A;  3U7D A;  1LW3 A;  1DRO A;  4HB2 B;  1TQZ A;  1X05 A;  2COA A;  1GG3 A;  2W2W A;  2AEH A;  4GNK B;  3SUZ A;  1GC7 A;  4YON A;  3KY9 A;  2YT2 A;  4CHM A;  2RSG A;  3D8E A;  2YS5 A;  3FM8 C;  3NWA A;  5C5B A;  2M38 A;  4A6F B;  1E5W A;  4A6K A;  1UPQ A;  4TKN A;  2L1C A;  2D9V A;  5JP4 A;  1V88 A;  5FI1 A;  3OAN A;  2DTC A;  4OT1 A;  2V76 A;  2NMB A;  4KHO A;  5CLL B;  1EF1 A;  1MKE A;  4MY6 A;  2D10 A;  2MKR A;  2CAY A;  4CHJ A;  3PVL A;  2GUM A;  4HAX B;  3M1I B;  2P0F A;  1BWN A;  2X18 A;  2CRF A;  1N3H A;  5LON B;  5KQ4 A;  2HE7 A;  2H7D A;  4IOY X;  4K2O A;  3O96 A;  4KHA A;  3DCX A;  3KRX A;  2YS1 A;  3HSA A;  4A6H A;  4Y94 A;  1TJ6 A;  2RRF A;  4WJ7 A;  2BCJ A;  1FOE A;  2UZS A;  3VOQ A;  4D6W A;  4KHB B;  3UZT A;  2KUQ A;  3RCP A;  1J0W A;  1DYN A;  1NTY A;  4EJN A;  3TW1 A;  2VSZ A;  1MIX A;  3A8Q A;  4KAX B;  1BTK A;  2LOZ A;  3ULC A;  3BJI A;  1RJ2 A;  1XD4 A;  2CY5 A;  1Y19 B;  1WGQ A;  2JP2 A;  3AJ4 A;  1GC6 A;  3A58 A;  1P6S A;  1V5P A;  1FGZ A;  2DYQ A;  4GMX B;  4KVG B;  4DBB A;  1BAK A;  1X86 A;  1XX0 A;  2MFQ A;  3HQC A;  4F7G A;  1UNR A;  1W1H A;  2I5F A;  3PVW A;  3NWF A;  3A98 B;  4DX9 0;  1FHO A;  1U29 A;  5EFX A;  2KIG A;  2HTH B;  3A8P A;  3KZ1 A;  1XCG A;  4CSQ A;  2EJ8 A;  4YL8 A;  1WG7 A;  5HE2 A;  1RRP B;  1DBH A;  1FGY A;  1BTN A;  4QJ5 B;  4P7I A;  1T77 A;  2W2X C;  4GPT B;  3QWM A;  2J0J A;  5D3W A;  4EKU A;  3WYF B;  5C16 A;  5JHH A;  3PZD A;  3T06 A;  1UNQ A;  2ZPY A;  3SNH A;  4BBK A;  5HE3 A;  4HAY B;  2D4Q A;  2ADZ A;  2Z0Q A;  1U27 A;  1ZC4 B;  2QKL A;  1XKE A;  2YT0 A;  2DKP A;  5IRS A;  2FJU B;  5C5B B;  5D27 A;  2NBV A;  2QKM A;  4GN1 A;  1ISN A;  4QXA B;  4Z2N A;  1I2H A;  3V5W A;  4A5K A;  1XR0 B;  2KIE A;  3ODX A;  3AU5 A;  2YT1 A;  3N7C A;  2D9Y A;  5CLQ B;  2NZ8 B;  5JHG A;  2EC1 A;  2N23 A;  2OQB A;  5D3V A;  1U5F A;  1MAI A;  1DDW A;  2P0D A;  4HSI A;  3FSS A;  4HAV B;  3TVV A;  2DN6 A;  2DX1 A;  2J0M A;  2ELA A;  2Z14 A;  4B6H A;  4DXA B;  2RNR B;  2K49 A;  2ELB A;  4MT7 A;  2Z59 A;  2PZ1 A;  3ZDT A;  2LUL A;  3NWD A;  3HW2 B;  1OMW A;  5LOP B;  3AU4 A;  4QJ3 B;  4HAT B;  2EMT A;  1DDM A;  1Z87 A;  4WSF A;  3WA0 A;  4L6E A;  4XWX A;  5KCV A;  1TXD A;  5KQ1 A;  2K8E A;  1WJM A;  4HAU B;  3B77 A;  1MI1 A;  4HHV A;  1AWE A;  1X1F A;  5DHA B;  2ROV A;  4Z2M B;  1H4R A;  3HK0 A;  4K2P A;  4NSW A;  4IAP A;  4C0A A;  1IRS A;  1ZM0 A;  1MK7 B;  1W1D A;  2RLO A;  3ULB A;  1J19 A;  2D9W A;  3FVC A;  4DIX A;  2LYD A;  4IFS A;  3TO1 A;  5C79 A;  2Y8F A;  1I7A A;  1EVH A;  3LJU X;  5J3T A;  2Y7B A;  3D8D A;  2KGX B;  1FHX A;  3SV1 A;  1OQN A;  1PFJ A;  2GS0 A;  3SYX A;  4L1R A;  2G35 A;  2KCJ A;  2AL6 A;  2XQN M;  3NSU A;  1U5D A;  4HB0 B;  2E2X A;  1SHC A;  3DXE A;  5J3Y A;  4GMV A;  5M4Y B;  2K2U A;  1XOD A;  2UZR A;  1U5G A;  3G9W A;  1W1G A;  1ZYI A;  1MPH A;  2KUP A;  4PQ0 A;  4EMO A;  5DI9 B;  1QQG A;  1K5G B;  2K2J A;  2RUK B;  1ZVR A;  2COF A;  4GOU A;  1WI1 A;  1ZC3 B;  3OHM B;  1UEF A;  5L81 A;  5FI0 A;  1ZSQ A;  3F0W A;  2D9X A;  2D11 A;  4OSN A;  1LB1 A;  3D8F A;  1V5M A;  2KR0 A;  2ZKM X;  5C6R A;  2GJY A;  4NY0 A;  3ODO A;  1Y5O A;  1X11 A;  4WVF B;  2UVM A;  2DHJ A;  2MDX A;  2RGN B;  2I5C A;  3MDB C;  4ZRI A;  4TYZ A;  4GZU A;  1X1G A;  1UPR A;  1NU2 A;  4PNK A;  5I2M A;  5GOW B;  4CYE A;  5LG4 B;  3QBV B;  4K81 A;  4HDO A;  2DHI A;  5DIF B; 
#chains in the Genus database with same CATH homology
 2LKO A;  2DX5 A;  4HB3 B;  4HAW B;  5HE1 A;  2VKI A;  1P3R A;  3GYO A;  3PP2 A;  5J3Q A;  2ROZ B;  2K00 A;  2M14 A;  2R0D A;  1UNP A;  2CY4 A;  2YS3 A;  1M7E A;  3CIK A;  2L2I A;  2Z0O A;  2YSZ A;  4DX8 A;  3DXD A;  2LG1 A;  3QIJ A;  2YRY A;  2YF0 A;  2EMS A;  3ODW A;  4GXB A;  3F5R A;  3P7Z A;  2VRW B;  2RVB B;  1V5U A;  2DYN A;  2J0K A;  4A6F A;  1M7R A;  1U5E A;  3PVU A;  2DA0 A;  4D0N B;  2I1J A;  3KSY A;  1KZ7 A;  2H7E A;  1MK9 B;  1V89 A;  4K17 A;  2N0Y A;  5D3X A;  2P8V A;  1MIZ B;  3P6A A;  4HB4 B;  1SGH A;  3ZVR A;  3TCA A;  4ZRJ A;  2MWN B;  4ZRK A;  1V61 A;  3FEH A;  2I1K A;  1FHW A;  2GCJ A;  3DXC A;  3U8Z A;  1Q67 A;  2GCL A;  2IFS A;  3BIN A;  1FB8 A;  5HE0 A;  3KRW A;  2Q13 A;  2OTX A;  3SO6 A;  1AQC A;  1WJ1 A;  2DKQ A;  4H8S A;  4HDQ A;  4F7H A;  2Z0P A;  1EAZ A;  2COD A;  3TFM A;  3IVF A;  2IYB A;  3PEG A;  2R09 A;  4F7U P;  2D9Z A;  1PMS A;  4MK0 A;  1NI2 A;  1EGX A;  1QC6 A;  2Y8G A;  1K5D B;  2COC A;  2DLW A;  5JLJ B;  1DDV A;  2DHK A;  2LOX A;  1WGU A;  1KI1 B;  1H10 A;  3GYP A;  5DHF B;  4HAZ B;  1P5T A;  1WVH A;  3X23 A;  1B55 A;  1OY2 A;  1PLS A;  1NTV A;  2FJL A;  2YVC A;  2D2Q A;  3PSC A;  1U2B A;  2P0H A;  3MPX A;  2W2X D;  3VIA A;  3CXB B;  1FAO A;  5DH9 B;  2J59 M;  1KZG A;  3ML4 A;  2DFK A;  3PG7 A;  5D3Y A;  3U7D A;  1LW3 A;  1DRO A;  4HB2 B;  1TQZ A;  1X05 A;  2COA A;  1GG3 A;  2W2W A;  2AEH A;  3SUZ A;  1GC7 A;  4YON A;  3KY9 A;  4CHM A;  2RSG A;  3D8E A;  2YS5 A;  3FM8 C;  5C5B A;  2M38 A;  4A6F B;  1E5W A;  4A6K A;  1UPQ A;  4TKN A;  2L1C A;  2D9V A;  5JP4 A;  1V88 A;  5FI1 A;  3OAN A;  2DTC A;  2V76 A;  2NMB A;  4KHO A;  5CLL B;  1EF1 A;  1MKE A;  4MY6 A;  2D10 A;  2MKR A;  2CAY A;  4CHJ A;  3PVL A;  4HAX B;  3M1I B;  2P0F A;  1BWN A;  2X18 A;  2CRF A;  1N3H A;  5LON B;  5KQ4 A;  2HE7 A;  2H7D A;  4IOY X;  4K2O A;  3O96 A;  4KHA A;  3KRX A;  2YS1 A;  4A6H A;  4Y94 A;  1TJ6 A;  4WJ7 A;  2BCJ A;  1FOE A;  2UZS A;  3VOQ A;  4KHB B;  3UZT A;  3RCP A;  1J0W A;  1DYN A;  1NTY A;  4EJN A;  3TW1 A;  2VSZ A;  1MIX A;  3A8Q A;  4KAX B;  1BTK A;  2LOZ A;  3ULC A;  3BJI A;  1RJ2 A;  1XD4 A;  2CY5 A;  1Y19 B;  1WGQ A;  2JP2 A;  3AJ4 A;  1GC6 A;  4GMX B;  1P6S A;  1V5P A;  1FGZ A;  2DYQ A;  4KVG B;  1BAK A;  4DBB A;  1X86 A;  1XX0 A;  2MFQ A;  3HQC A;  4F7G A;  1UNR A;  1W1H A;  2I5F A;  3PVW A;  3A98 B;  4DX9 0;  1FHO A;  1U29 A;  5EFX A;  2HTH B;  3A8P A;  3KZ1 A;  1XCG A;  2EJ8 A;  4YL8 A;  1WG7 A;  5HE2 A;  1RRP B;  1DBH A;  1FGY A;  1BTN A;  4P7I A;  2W2X C;  4GPT B;  3QWM A;  2J0J A;  5D3W A;  4EKU A;  3WYF B;  5C16 A;  5JHH A;  3PZD A;  3T06 A;  1UNQ A;  2ZPY A;  3SNH A;  4BBK A;  5HE3 A;  4HAY B;  2D4Q A;  2ADZ A;  2Z0Q A;  1U27 A;  1ZC4 B;  2QKL A;  1XKE A;  2YT0 A;  2DKP A;  5C5B B;  5D27 A;  2QKM A;  4GN1 A;  1ISN A;  4Z2N A;  1I2H A;  3V5W A;  4A5K A;  1XR0 B;  3ODX A;  3AU5 A;  2YT1 A;  3N7C A;  2D9Y A;  5CLQ B;  2NZ8 B;  5JHG A;  2EC1 A;  2N23 A;  2OQB A;  5D3V A;  1U5F A;  1MAI A;  1DDW A;  2P0D A;  3FSS A;  4HAV B;  3TVV A;  2DN6 A;  2DX1 A;  2J0M A;  2ELA A;  4B6H A;  4DXA B;  2RNR B;  2ELB A;  4MT7 A;  2PZ1 A;  3ZDT A;  2LUL A;  3HW2 B;  1OMW A;  5LOP B;  3AU4 A;  4HAT B;  2EMT A;  1DDM A;  1Z87 A;  4WSF A;  3WA0 A;  4L6E A;  4XWX A;  5KCV A;  1TXD A;  5KQ1 A;  1WJM A;  4HAU B;  4HHV A;  1AWE A;  1X1F A;  5DHA B;  2ROV A;  4Z2M B;  1H4R A;  3HK0 A;  4K2P A;  4NSW A;  4IAP A;  4C0A A;  1IRS A;  1ZM0 A;  1MK7 B;  1W1D A;  2RLO A;  3ULB A;  1J19 A;  2D9W A;  2LYD A;  4IFS A;  3TO1 A;  5C79 A;  2Y8F A;  1I7A A;  1EVH A;  3LJU X;  5J3T A;  2Y7B A;  3D8D A;  2KGX B;  1FHX A;  3SV1 A;  1OQN A;  1PFJ A;  2GS0 A;  3SYX A;  2G35 A;  2KCJ A;  2AL6 A;  2XQN M;  3NSU A;  1U5D A;  4HB0 B;  2E2X A;  1SHC A;  3DXE A;  5J3Y A;  4GMV A;  2K2U A;  1XOD A;  2UZR A;  1U5G A;  3G9W A;  1W1G A;  1MPH A;  2KUP A;  4PQ0 A;  4EMO A;  5DI9 B;  1QQG A;  1K5G B;  2K2J A;  2RUK B;  1ZVR A;  2COF A;  1WI1 A;  1ZC3 B;  1UEF A;  5L81 A;  5FI0 A;  1ZSQ A;  3F0W A;  2D9X A;  2D11 A;  1LB1 A;  3D8F A;  1V5M A;  5C6R A;  2GJY A;  4NY0 A;  3ODO A;  1Y5O A;  1X11 A;  4WVF B;  2UVM A;  2DHJ A;  2MDX A;  2RGN B;  2I5C A;  3MDB C;  4ZRI A;  4TYZ A;  4GZU A;  1X1G A;  1UPR A;  1NU2 A;  4PNK A;  5GOW B;  4CYE A;  3QBV B;  4K81 A;  4HDO A;  2DHI A;  5DIF B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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