4HAWB

Crystal structure of crm1 inhibitor leptomycin b in complex with crm1(k548a)-ran-ranbp1
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
138
structure length
131
Chain Sequence
IHFEPVVKTMEEDEEVLYKVRAKLFRFDKDAKEWKERGTGDCKFLKNKKTNKVRILMRRDKTLKICANHIIAPEYTLKPNVGSDRSWVYACTADIAEGEAEAFTFAIRFGSKENADKFKEEFEKAQEINKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
pubmed doi rcsb
molecule tags Protein transport/antibiotic
source organism Homo sapiens
molecule keywords GTP-binding nuclear protein Ran
total genus 36
structure length 131
sequence length 138
ec nomenclature
pdb deposition date 2012-09-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00638 Ran_BP1 RanBP1 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 4hawB00
2LYDA 1UPRA 1FOEA 2GCJA 3A8PA 4A6HA 1SHCA 2D9YA 3ZVRA 1MPHA 5D3WA 2DYQA 2MWNB 2DKPA 3D8FA 1EF1A 3P7ZA 5HE0A 2DHJA 4CHJA 5HE2A 2UZRA 1XKEA 1J19A 1X05A 1NTYA 2DKQA 4HDOA 4C0AA 1FHOA 1U5FA 5C5BB 3VOQA 3SYXA 3PVLA 3O96A 4PNKA 5GOWB 1MIXA 1WGQA 1X1GA 2UZSA 2ELAA 1H4RA 1UNRA 2I1KA 4HAVB 5C6RA 1N3HA 1XODA 1E5WA 5CLQB 2LG1A 4GZUA 2J0MA 4KHOA 2I5FA 1MK7B 3A8QA 1X1FA 4F7GA 5C5BA 4WSFA 1BAKA 2YT1A 2COCA 2IFSA 4A5KA 1DDWA 2YRYA 1WG7A 1W1GA 1V5MA 4HB0B 2W2WA 5DIFB 2D4QA 3FEHA 3MPXA 4H8SA 1P3RA 4WVFB 4ZRJA 2LULA 2D9VA 3KSYA 4K2PA 5J3YA 1FGYA 3LJUX 1PLSA 1EVHA 2P8VA 4TKNA 2M38A 1QQGA 5KQ1A 1UEFA 2DTCA 3AU4A 3CXBB 4GMXB 1U5GA 5L81A 4DX8A 2I5CA 2COAA 1W1DA 1V89A 3SNHA 2NMBA 5DHAB 1AWEA 2N23A 3VIAA 5FI1A 4CYEA 3D8EA 2YSZA 3ML4A 4EJNA 2J0JA 4WJ7A 4DBBA 2EJ8A 3FSSA 2VKIA 1V88A 4PQ0A 1TJ6A 3KRXA 5HE3A 4KHAA 1FB8A 3WA0A 2MKRA 5J3QA 2LOZA 2R0DA 3PVWA 2ADZA 2D11A 2L2IA 2MDXA 1ZM0A 2PZ1A 2RGNB 2GJYA 4HATB 2D9WA 2K00A 1NU2A 3ODXA 3PEGA 4NSWA 1XCGA 2VSZA 4DXAB 3GYPA 1XD4A 1Q67A 5J3TA 2D2QA 5JLJB 1B55A 4YL8A 1M7RA 2DHKA 3AJ4A 4MK0A 1BWNA 1DBHA 2ZPYA 4IAPA 1NTVA 3SO6A 3TW1A 1WVHA 4GXBA 2X18A 2D10A 4GPTB 2GCLA 1ISNA 2Q13A 2QKLA 3KRWA 4GMVA 4IFSA 1FAOA 1ZVRA 3ULBA 2UVMA 4IOYX 4EMOA 3PP2A 1MAIA 1EAZA 4HAUB 1BTNA 1SGHA 2K2UA 5EFXA 1FGZA 2GS0A 2RSGA 1V5PA 2YS1A 5JHHA 2OQBA 1MIZB 1OMWA 2CODA 4YONA 5D3YA 5FI0A 2Y8FA 1DYNA 4BBKA 3M1IB 1U5DA 1KZGA 3PG7A 1H10A 4HB4B 4D0NB 1AQCA 2COFA 2N0YA 2AEHA 1V5UA 2ELBA 3KZ1A 2DYNA 4HB3B 4KAXB 5CLLB 2Z0OA 2DX1A 2DA0A 2RUKB 1P6SA 4P7IA 4EKUA 3AU5A 4MT7A 2KCJA 1KZ7A 2MFQA 2DFKA 2YT0A 1DDMA 4KHBB 2RNRB 2Y8GA 4Y94A 2LOXA 2EMSA 5DH9B 3D8DA 3QWMA 3UZTA 1UPQA 3HW2B 2M14A 4F7UP 1U5EA 2Z0PA 4DX90 1WJ1A 3U7DA 1X86A 2Z0QA 3TVVA 1OY2A 4HAXB 4NY0A 3SUZA 4K17A 2QKMA 2ROZB 2D9ZA 5LOPB 1P5TA 3TO1A 2FJLA 1M7EA 1Y19B 3QBVB 2DHIA 5D3VA 1Z87A 1K5GB 1Y5OA 4KVGB 2EC1A 4A6FB 1ZSQA 3DXDA 3SV1A 3F0WA 2YVCA 4GN1A 3WYFB 3BJIA 4F7HA 2CY5A 3KY9A 5DHFB 1GC6A 1UNPA 4ZRIA 4ZRKA 1LB1A 3PZDA 3DXCA 3ULCA 1WJMA 5HE1A 2L1CA 4HHVA 3ZDTA 3TCAA 1XX0A 4A6FA 2R09A 3A98B 1KI1B 1X11A 1TXDA 2AL6A 2KUPA 2IYBA 2H7EA 3CIKA 1RRPB 2H7DA 3N7CA 5DI9B 5KCVA 2J59M 3V5WA 4Z2NA 3FM8C 2CY4A 2D9XA 4A6KA 2OTXA 1LW3A 2I1JA 1U2BA 1ZC4B 5C16A 5C79A 2HTHB 4HDQA 3ODWA 1PFJA 2HE7A 4MY6A 2LKOA 4TYZA 2EMTA 2DLWA 2E2XA 3U8ZA 1PMSA 2W2XD 2RLOA 1ZC3B 5JP4A 5D3XA 2Y7BA 1RJ2A 2K2JA 4XWXA 1GC7A 1IRSA 1DROA 1K5DB 2ROVA 1U29A 2P0HA 3PVUA 4HAZB 1OQNA 3DXEA 1DDVA 2RVBB 5JHGA 1J0WA 2BCJA 3F5RA 3NSUA 3PSCA 2P0FA 1QC6A 3MDBC 2J0KA 4HAWB 1EGXA 3BINA 2DN6A 2G35A 1I2HA 3P6AA 4K2OA 1XR0B 3GYOA 2P0DA 3RCPA 3G9WA 1V61A 1WGUA 4HAYB 1FHWA 1GG3A 2DX5A 3HK0A 3TFMA 2YF0A 3T06A 2VRWB 1NI2A 4L6EA 2JP2A 4Z2MB 2CRFA 2NZ8B 5LONB 1UNQA 1W1HA 2YS5A 3ODOA 5KQ4A 1U27A 4K81A 3QIJA 2YS3A 3OANA 1BTKA 4B6HA 2W2XC 1I7AA 1TQZA 1MKEA 1MK9B 4CHMA 2KGXB 3X23A 3IVFA 5D27A 1WI1A 1FHXA 4HB2B 2V76A 3HQCA 2XQNM 2CAYA
chains in the Genus database with same CATH superfamily
2LYDA 1UPRA 1FOEA 2GCJA 3A8PA 4A6HA 1SHCA 2D9YA 3ZVRA 1MPHA 5D3WA 2DYQA 2MWNB 2DKPA 3D8FA 3DCXA 1EF1A 3P7ZA 5HE0A 2DHJA 4CHJA 5I2SA 5HE2A 2UZRA 1XKEA 1J19A 1X05A 1NTYA 2DKQA 4HDOA 4OT1A 4C0AA 1FHOA 1T77A 1U5FA 5C5BB 3VOQA 3SYXA 3PVLA 3O96A 4PNKA 5GOWB 1MIXA 1WGQA 1X1GA 2UZSA 2ELAA 1H4RA 1UNRA 2I1KA 3OHMB 4HAVB 5C6RA 1N3HA 1XODA 1E5WA 5CLQB 2LG1A 4GZUA 2J0MA 4KHOA 2I5FA 1MK7B 3A8QA 1X1FA 4GOUA 4F7GA 5C5BA 4WSFA 1BAKA 2YT1A 2COCA 2IFSA 4A5KA 1DDWA 2YRYA 1WG7A 1W1GA 1V5MA 4HB0B 2W2WA 5DIFB 2D4QA 3FEHA 3MPXA 4H8SA 1P3RA 4WVFB 4ZRJA 2LULA 2D9VA 3KSYA 4K2PA 5J3YA 3A58A 1FGYA 3LJUX 3U12A 1PLSA 1EVHA 4DIXA 2P8VA 4TKNA 2M38A 1QQGA 5KQ1A 1UEFA 2DTCA 3AU4A 3CXBB 4GMXB 1U5GA 5L81A 4DX8A 2I5CA 2COAA 1W1DA 1V89A 3SNHA 2NMBA 5DHAB 1AWEA 5M4YB 2N23A 3VIAA 5FI1A 4CYEA 3D8EA 2YSZA 3ML4A 4EJNA 4QJ4B 2J0JA 4WJ7A 4L1RA 4DBBA 2EJ8A 3FSSA 2VKIA 1V88A 4PQ0A 1TJ6A 3KRXA 5HE3A 4KHAA 1FB8A 3WA0A 2MKRA 5J3QA 2LOZA 2R0DA 3PVWA 5I2MA 2ADZA 2D11A 2L2IA 2MDXA 1ZM0A 2PZ1A 2RGNB 2GJYA 4HATB 2D9WA 2K00A 1NU2A 3ODXA 3PEGA 4NSWA 1XCGA 2VSZA 4DXAB 3GYPA 1XD4A 1Q67A 5J3TA 2D2QA 2GUMA 5JLJB 1B55A 4YL8A 1M7RA 2DHKA 3AJ4A 4MK0A 1BWNA 1DBHA 2K49A 2ZPYA 4IAPA 1NTVA 3SO6A 4QJ5B 3TW1A 1WVHA 4GXBA 2X18A 2D10A 4GPTB 2GCLA 1ISNA 2Q13A 2QKLA 3KRWA 4GMVA 4IFSA 1FAOA 1ZVRA 2Z13A 3ULBA 2UVMA 4IOYX 4EMOA 4HSIA 3PP2A 1MAIA 1EAZA 4HAUB 1BTNA 1SGHA 2K2UA 5EFXA 1FGZA 2GS0A 2RSGA 1V5PA 2YS1A 5JHHA 2OQBA 1MIZB 1OMWA 2KIEA 2CODA 4YONA 5D3YA 5FI0A 2Y8FA 1DYNA 4BBKA 3M1IB 1U5DA 1KZGA 3PG7A 4CSQA 1H10A 4HB4B 4D0NB 1AQCA 2COFA 2N0YA 2AEHA 1V5UA 2ELBA 3KZ1A 2DYNA 4HB3B 4KAXB 5CLLB 2Z0OA 2DX1A 2DA0A 2RUKB 1P6SA 4P7IA 4EKUA 3AU5A 4MT7A 2KCJA 1KZ7A 2MFQA 4OSNA 2DFKA 2YT0A 1DDMA 4KHBB 2RNRB 2Y8GA 4Y94A 2LOXA 2EMSA 5DH9B 3HSAA 3D8DA 3QWMA 3UZTA 1UPQA 3HW2B 2KR0A 2M14A 4F7UP 1U5EA 2Z0PA 4DX90 1WJ1A 3U7DA 1X86A 2K8EA 4GNKB 2Z0QA 3TVVA 1OY2A 4HAXB 4NY0A 3SUZA 5IRSA 4K17A 2QKMA 2ROZB 2D9ZA 5LOPB 1P5TA 3TO1A 2FJLA 1M7EA 1Y19B 3QBVB 2DHIA 5D3VA 2NBVA 1Z87A 1K5GB 1Y5OA 4KVGB 2EC1A 4A6FB 1ZSQA 3DXDA 3SV1A 3F0WA 2YVCA 4GN1A 3WYFB 3BJIA 4F7HA 2CY5A 3KY9A 5DHFB 1GC6A 1UNPA 2ZKMX 4ZRIA 4ZRKA 1LB1A 3PZDA 3DXCA 3ULCA 1WJMA 5HE1A 2L1CA 4QXAB 4HHVA 3ZDTA 3TCAA 1XX0A 4A6FA 2R09A 3A98B 1KI1B 3NWAA 1X11A 2YT2A 1TXDA 2Z14A 2AL6A 2KUPA 2IYBA 2H7EA 4D6WA 3CIKA 1RRPB 2KIGA 2H7DA 3N7CA 5DI9B 5KCVA 2J59M 3V5WA 4Z2NA 3FM8C 2CY4A 2D9XA 4A6KA 2OTXA 1LW3A 2I1JA 1U2BA 1ZC4B 5C16A 1MI1A 5C79A 3B77A 3NWDA 2HTHB 4HDQA 3ODWA 1PFJA 2HE7A 4MY6A 2LKOA 4TYZA 2EMTA 2DLWA 2E2XA 4QJ3B 3U8ZA 1PMSA 2W2XD 2RLOA 1ZC3B 2RRFA 5D3XA 2Y7BA 5JP4A 1RJ2A 2K2JA 1ZYIA 2Z4DA 1GC7A 4XWXA 1IRSA 1DROA 1K5DB 2ROVA 1U29A 2P0HA 3PVUA 4HAZB 1OQNA 2Z59A 3DXEA 1DDVA 2RVBB 5JHGA 1J0WA 2BCJA 3F5RA 2FJUB 3NSUA 3PSCA 2P0FA 1QC6A 3MDBC 2J0KA 4HAWB 1EGXA 3BINA 3NW8A 2DN6A 3FVCA 2G35A 1I2HA 4KHBA 3P6AA 4K2OA 1XR0B 3GYOA 2KUQA 5LG4B 2P0DA 3RCPA 3G9WA 1V61A 1WGUA 4HAYB 1FHWA 1GG3A 2DX5A 3HK0A 3TFMA 2YF0A 3T06A 2VRWB 1NI2A 4L6EA 2JP2A 4Z2MB 2CRFA 2NZ8B 5LONB 1UNQA 1W1HA 2YS5A 3ODOA 5KQ4A 1U27A 4K81A 3QIJA 2YS3A 3HIEA 3OANA 1BTKA 4B6HA 2W2XC 1I7AA 1TQZA 1MKEA 1MK9B 4CHMA 2KGXB 3X23A 3IVFA 5D27A 1WI1A 2R2YA 3NWFA 1FHXA 4HB2B 2V76A 3HQCA 2XQNM 2CAYA
chains in the Genus database with same CATH topology
2LYDA 1UPRA 1FOEA 2GCJA 3A8PA 4A6HA 1SHCA 2D9YA 3ZVRA 1MPHA 5D3WA 2DYQA 2MWNB 2DKPA 3D8FA 1EF1A 3P7ZA 5HE0A 2DHJA 4CHJA 5HE2A 2UZRA 1XKEA 1J19A 1X05A 1NTYA 2DKQA 4HDOA 4C0AA 1FHOA 1U5FA 5C5BB 3VOQA 3SYXA 3PVLA 3O96A 4PNKA 5GOWB 1MIXA 1WGQA 1X1GA 2UZSA 2ELAA 1H4RA 1UNRA 2I1KA 4HAVB 5C6RA 1N3HA 1XODA 1E5WA 5CLQB 2LG1A 4GZUA 2J0MA 4KHOA 2I5FA 1MK7B 3A8QA 1X1FA 4F7GA 5C5BA 4WSFA 1BAKA 2YT1A 2COCA 2IFSA 4A5KA 1DDWA 2YRYA 1WG7A 1W1GA 1V5MA 4HB0B 2W2WA 5DIFB 2D4QA 3FEHA 3MPXA 4H8SA 1P3RA 4WVFB 4ZRJA 2LULA 2D9VA 3KSYA 4K2PA 5J3YA 1FGYA 3LJUX 1PLSA 1EVHA 2P8VA 4TKNA 2M38A 1QQGA 5KQ1A 1UEFA 2DTCA 3AU4A 3CXBB 4GMXB 1U5GA 5L81A 4DX8A 2I5CA 2COAA 1W1DA 1V89A 3SNHA 2NMBA 5DHAB 1AWEA 2N23A 3VIAA 5FI1A 4CYEA 3D8EA 2YSZA 3ML4A 4EJNA 2J0JA 4WJ7A 4DBBA 2EJ8A 3FSSA 2VKIA 1V88A 4PQ0A 1TJ6A 3KRXA 5HE3A 4KHAA 1FB8A 3WA0A 2MKRA 5J3QA 2LOZA 2R0DA 3PVWA 2ADZA 2D11A 2L2IA 2MDXA 1ZM0A 2PZ1A 2RGNB 2GJYA 4HATB 2D9WA 2K00A 1NU2A 3ODXA 3PEGA 4NSWA 1XCGA 2VSZA 4DXAB 3GYPA 1XD4A 1Q67A 5J3TA 2D2QA 5JLJB 1B55A 4YL8A 1M7RA 2DHKA 3AJ4A 4MK0A 1BWNA 1DBHA 2ZPYA 4IAPA 1NTVA 3SO6A 3TW1A 1WVHA 4GXBA 2X18A 2D10A 4GPTB 2GCLA 1ISNA 2Q13A 2QKLA 3KRWA 4GMVA 4IFSA 1FAOA 1ZVRA 3ULBA 2UVMA 4IOYX 4EMOA 3PP2A 1MAIA 1EAZA 4HAUB 1BTNA 1SGHA 2K2UA 5EFXA 1FGZA 2GS0A 2RSGA 1V5PA 2YS1A 5JHHA 2OQBA 1MIZB 1OMWA 2CODA 4YONA 5D3YA 5FI0A 2Y8FA 1DYNA 4BBKA 3M1IB 1U5DA 1KZGA 3PG7A 1H10A 4HB4B 4D0NB 1AQCA 2COFA 2N0YA 2AEHA 1V5UA 2ELBA 3KZ1A 2DYNA 4HB3B 4KAXB 5CLLB 2Z0OA 2DX1A 2DA0A 2RUKB 1P6SA 4P7IA 4EKUA 3AU5A 4MT7A 2KCJA 1KZ7A 2MFQA 2DFKA 2YT0A 1DDMA 4KHBB 2RNRB 2Y8GA 4Y94A 2LOXA 2EMSA 5DH9B 3D8DA 3QWMA 3UZTA 1UPQA 3HW2B 2M14A 4F7UP 1U5EA 2Z0PA 4DX90 1WJ1A 3U7DA 1X86A 2Z0QA 3TVVA 1OY2A 4HAXB 4NY0A 3SUZA 4K17A 2QKMA 2ROZB 2D9ZA 5LOPB 1P5TA 3TO1A 2FJLA 1M7EA 1Y19B 3QBVB 2DHIA 5D3VA 1Z87A 1K5GB 1Y5OA 4KVGB 2EC1A 4A6FB 1ZSQA 3DXDA 3SV1A 3F0WA 2YVCA 4GN1A 3WYFB 3BJIA 4F7HA 2CY5A 3KY9A 5DHFB 1GC6A 1UNPA 4ZRIA 4ZRKA 1LB1A 3PZDA 3DXCA 3ULCA 1WJMA 5HE1A 2L1CA 4HHVA 3ZDTA 3TCAA 1XX0A 4A6FA 2R09A 3A98B 1KI1B 1X11A 1TXDA 2AL6A 2KUPA 2IYBA 2H7EA 3CIKA 1RRPB 2H7DA 3N7CA 5DI9B 5KCVA 2J59M 3V5WA 4Z2NA 3FM8C 2CY4A 2D9XA 4A6KA 2OTXA 1LW3A 2I1JA 1U2BA 1ZC4B 5C16A 5C79A 2HTHB 4HDQA 3ODWA 1PFJA 2HE7A 4MY6A 2LKOA 4TYZA 2EMTA 2DLWA 2E2XA 3U8ZA 1PMSA 2W2XD 2RLOA 1ZC3B 5JP4A 5D3XA 2Y7BA 1RJ2A 2K2JA 4XWXA 1GC7A 1IRSA 1DROA 1K5DB 2ROVA 1U29A 2P0HA 3PVUA 4HAZB 1OQNA 3DXEA 1DDVA 2RVBB 5JHGA 1J0WA 2BCJA 3F5RA 3NSUA 3PSCA 2P0FA 1QC6A 3MDBC 2J0KA 4HAWB 1EGXA 3BINA 2DN6A 2G35A 1I2HA 3P6AA 4K2OA 1XR0B 3GYOA 2P0DA 3RCPA 3G9WA 1V61A 1WGUA 4HAYB 1FHWA 1GG3A 2DX5A 3HK0A 3TFMA 2YF0A 3T06A 2VRWB 1NI2A 4L6EA 2JP2A 4Z2MB 2CRFA 2NZ8B 5LONB 1UNQA 1W1HA 2YS5A 3ODOA 5KQ4A 1U27A 4K81A 3QIJA 2YS3A 3OANA 1BTKA 4B6HA 2W2XC 1I7AA 1TQZA 1MKEA 1MK9B 4CHMA 2KGXB 3X23A 3IVFA 5D27A 1WI1A 1FHXA 4HB2B 2V76A 3HQCA 2XQNM 2CAYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LYD A;  1UPR A;  1FOE A;  2GCJ A;  3A8P A;  4A6H A;  1SHC A;  2D9Y A;  3ZVR A;  1MPH A;  5D3W A;  2DYQ A;  2MWN B;  2DKP A;  3D8F A;  1EF1 A;  3P7Z A;  5HE0 A;  2DHJ A;  4CHJ A;  5HE2 A;  2UZR A;  1XKE A;  1J19 A;  1X05 A;  1NTY A;  2DKQ A;  4HDO A;  4C0A A;  1FHO A;  1U5F A;  5C5B B;  3VOQ A;  3SYX A;  3PVL A;  3O96 A;  4PNK A;  5GOW B;  1MIX A;  1WGQ A;  1X1G A;  2UZS A;  2ELA A;  1H4R A;  1UNR A;  2I1K A;  4HAV B;  5C6R A;  1N3H A;  1XOD A;  1E5W A;  5CLQ B;  2LG1 A;  4GZU A;  2J0M A;  4KHO A;  2I5F A;  1MK7 B;  3A8Q A;  1X1F A;  4F7G A;  5C5B A;  4WSF A;  1BAK A;  2YT1 A;  2COC A;  2IFS A;  4A5K A;  1DDW A;  2YRY A;  1WG7 A;  1W1G A;  1V5M A;  4HB0 B;  2W2W A;  5DIF B;  2D4Q A;  3FEH A;  3MPX A;  4H8S A;  1P3R A;  4WVF B;  4ZRJ A;  2LUL A;  2D9V A;  3KSY A;  4K2P A;  5J3Y A;  1FGY A;  3LJU X;  1PLS A;  1EVH A;  2P8V A;  4TKN A;  2M38 A;  1QQG A;  5KQ1 A;  1UEF A;  2DTC A;  3AU4 A;  3CXB B;  4GMX B;  1U5G A;  5L81 A;  4DX8 A;  2I5C A;  2COA A;  1W1D A;  1V89 A;  3SNH A;  2NMB A;  5DHA B;  1AWE A;  2N23 A;  3VIA A;  5FI1 A;  4CYE A;  3D8E A;  2YSZ A;  3ML4 A;  4EJN A;  2J0J A;  4WJ7 A;  4DBB A;  2EJ8 A;  3FSS A;  2VKI A;  1V88 A;  4PQ0 A;  1TJ6 A;  3KRX A;  5HE3 A;  4KHA A;  1FB8 A;  3WA0 A;  2MKR A;  5J3Q A;  2LOZ A;  2R0D A;  3PVW A;  2ADZ A;  2D11 A;  2L2I A;  2MDX A;  1ZM0 A;  2PZ1 A;  2RGN B;  2GJY A;  4HAT B;  2D9W A;  2K00 A;  1NU2 A;  3ODX A;  3PEG A;  4NSW A;  1XCG A;  2VSZ A;  4DXA B;  3GYP A;  1XD4 A;  1Q67 A;  5J3T A;  2D2Q A;  5JLJ B;  1B55 A;  4YL8 A;  1M7R A;  2DHK A;  3AJ4 A;  4MK0 A;  1BWN A;  1DBH A;  2ZPY A;  4IAP A;  1NTV A;  3SO6 A;  3TW1 A;  1WVH A;  4GXB A;  2X18 A;  2D10 A;  4GPT B;  2GCL A;  1ISN A;  2Q13 A;  2QKL A;  3KRW A;  4GMV A;  4IFS A;  1FAO A;  1ZVR A;  3ULB A;  2UVM A;  4IOY X;  4EMO A;  3PP2 A;  1MAI A;  1EAZ A;  4HAU B;  1BTN A;  1SGH A;  2K2U A;  5EFX A;  1FGZ A;  2GS0 A;  2RSG A;  1V5P A;  2YS1 A;  5JHH A;  2OQB A;  1MIZ B;  1OMW A;  2COD A;  4YON A;  5D3Y A;  5FI0 A;  2Y8F A;  1DYN A;  4BBK A;  3M1I B;  1U5D A;  1KZG A;  3PG7 A;  1H10 A;  4HB4 B;  4D0N B;  1AQC A;  2COF A;  2N0Y A;  2AEH A;  1V5U A;  2ELB A;  3KZ1 A;  2DYN A;  4HB3 B;  4KAX B;  5CLL B;  2Z0O A;  2DX1 A;  2DA0 A;  2RUK B;  1P6S A;  4P7I A;  4EKU A;  3AU5 A;  4MT7 A;  2KCJ A;  1KZ7 A;  2MFQ A;  2DFK A;  2YT0 A;  1DDM A;  4KHB B;  2RNR B;  2Y8G A;  4Y94 A;  2LOX A;  2EMS A;  5DH9 B;  3D8D A;  3QWM A;  3UZT A;  1UPQ A;  3HW2 B;  2M14 A;  4F7U P;  1U5E A;  2Z0P A;  4DX9 0;  1WJ1 A;  3U7D A;  1X86 A;  2Z0Q A;  3TVV A;  1OY2 A;  4HAX B;  4NY0 A;  3SUZ A;  4K17 A;  2QKM A;  2ROZ B;  2D9Z A;  5LOP B;  1P5T A;  3TO1 A;  2FJL A;  1M7E A;  1Y19 B;  3QBV B;  2DHI A;  5D3V A;  1Z87 A;  1K5G B;  1Y5O A;  4KVG B;  2EC1 A;  4A6F B;  1ZSQ A;  3DXD A;  3SV1 A;  3F0W A;  2YVC A;  4GN1 A;  3WYF B;  3BJI A;  4F7H A;  2CY5 A;  3KY9 A;  5DHF B;  1GC6 A;  1UNP A;  4ZRI A;  4ZRK A;  1LB1 A;  3PZD A;  3DXC A;  3ULC A;  1WJM A;  5HE1 A;  2L1C A;  4HHV A;  3ZDT A;  3TCA A;  1XX0 A;  4A6F A;  2R09 A;  3A98 B;  1KI1 B;  1X11 A;  1TXD A;  2AL6 A;  2KUP A;  2IYB A;  2H7E A;  3CIK A;  1RRP B;  2H7D A;  3N7C A;  5DI9 B;  5KCV A;  2J59 M;  3V5W A;  4Z2N A;  3FM8 C;  2CY4 A;  2D9X A;  4A6K A;  2OTX A;  1LW3 A;  2I1J A;  1U2B A;  1ZC4 B;  5C16 A;  5C79 A;  2HTH B;  4HDQ A;  3ODW A;  1PFJ A;  2HE7 A;  4MY6 A;  2LKO A;  4TYZ A;  2EMT A;  2DLW A;  2E2X A;  3U8Z A;  1PMS A;  2W2X D;  2RLO A;  1ZC3 B;  5JP4 A;  5D3X A;  2Y7B A;  1RJ2 A;  2K2J A;  4XWX A;  1GC7 A;  1IRS A;  1DRO A;  1K5D B;  2ROV A;  1U29 A;  2P0H A;  3PVU A;  4HAZ B;  1OQN A;  3DXE A;  1DDV A;  2RVB B;  5JHG A;  1J0W A;  2BCJ A;  3F5R A;  3NSU A;  3PSC A;  2P0F A;  1QC6 A;  3MDB C;  2J0K A;  4HAW B;  1EGX A;  3BIN A;  2DN6 A;  2G35 A;  1I2H A;  3P6A A;  4K2O A;  1XR0 B;  3GYO A;  2P0D A;  3RCP A;  3G9W A;  1V61 A;  1WGU A;  4HAY B;  1FHW A;  1GG3 A;  2DX5 A;  3HK0 A;  3TFM A;  2YF0 A;  3T06 A;  2VRW B;  1NI2 A;  4L6E A;  2JP2 A;  4Z2M B;  2CRF A;  2NZ8 B;  5LON B;  1UNQ A;  1W1H A;  2YS5 A;  3ODO A;  5KQ4 A;  1U27 A;  4K81 A;  3QIJ A;  2YS3 A;  3OAN A;  1BTK A;  4B6H A;  2W2X C;  1I7A A;  1TQZ A;  1MKE A;  1MK9 B;  4CHM A;  2KGX B;  3X23 A;  3IVF A;  5D27 A;  1WI1 A;  1FHX A;  4HB2 B;  2V76 A;  3HQC A;  2XQN M;  2CAY A; 
#chains in the Genus database with same CATH topology
 2LYD A;  1UPR A;  1FOE A;  2GCJ A;  3A8P A;  4A6H A;  1SHC A;  2D9Y A;  3ZVR A;  1MPH A;  5D3W A;  2DYQ A;  2MWN B;  2DKP A;  3D8F A;  3DCX A;  1EF1 A;  3P7Z A;  5HE0 A;  2DHJ A;  4CHJ A;  5I2S A;  5HE2 A;  2UZR A;  1XKE A;  1J19 A;  1X05 A;  1NTY A;  2DKQ A;  4HDO A;  4OT1 A;  4C0A A;  1FHO A;  1T77 A;  1U5F A;  5C5B B;  3VOQ A;  3SYX A;  3PVL A;  3O96 A;  4PNK A;  5GOW B;  1MIX A;  1WGQ A;  1X1G A;  2UZS A;  2ELA A;  1H4R A;  1UNR A;  2I1K A;  3OHM B;  4HAV B;  5C6R A;  1N3H A;  1XOD A;  1E5W A;  5CLQ B;  2LG1 A;  4GZU A;  2J0M A;  4KHO A;  2I5F A;  1MK7 B;  3A8Q A;  1X1F A;  4GOU A;  4F7G A;  5C5B A;  4WSF A;  1BAK A;  2YT1 A;  2COC A;  2IFS A;  4A5K A;  1DDW A;  2YRY A;  1WG7 A;  1W1G A;  1V5M A;  4HB0 B;  2W2W A;  5DIF B;  2D4Q A;  3FEH A;  3MPX A;  4H8S A;  1P3R A;  4WVF B;  4ZRJ A;  2LUL A;  2D9V A;  3KSY A;  4K2P A;  5J3Y A;  3A58 A;  1FGY A;  3LJU X;  3U12 A;  1PLS A;  1EVH A;  4DIX A;  2P8V A;  4TKN A;  2M38 A;  1QQG A;  5KQ1 A;  1UEF A;  2DTC A;  3AU4 A;  3CXB B;  4GMX B;  1U5G A;  5L81 A;  4DX8 A;  2I5C A;  2COA A;  1W1D A;  1V89 A;  3SNH A;  2NMB A;  5DHA B;  1AWE A;  5M4Y B;  2N23 A;  3VIA A;  5FI1 A;  4CYE A;  3D8E A;  2YSZ A;  3ML4 A;  4EJN A;  4QJ4 B;  2J0J A;  4WJ7 A;  4L1R A;  4DBB A;  2EJ8 A;  3FSS A;  2VKI A;  1V88 A;  4PQ0 A;  1TJ6 A;  3KRX A;  5HE3 A;  4KHA A;  1FB8 A;  3WA0 A;  2MKR A;  5J3Q A;  2LOZ A;  2R0D A;  3PVW A;  5I2M A;  2ADZ A;  2D11 A;  2L2I A;  2MDX A;  1ZM0 A;  2PZ1 A;  2RGN B;  2GJY A;  4HAT B;  2D9W A;  2K00 A;  1NU2 A;  3ODX A;  3PEG A;  4NSW A;  1XCG A;  2VSZ A;  4DXA B;  3GYP A;  1XD4 A;  1Q67 A;  5J3T A;  2D2Q A;  2GUM A;  5JLJ B;  1B55 A;  4YL8 A;  1M7R A;  2DHK A;  3AJ4 A;  4MK0 A;  1BWN A;  1DBH A;  2K49 A;  2ZPY A;  4IAP A;  1NTV A;  3SO6 A;  4QJ5 B;  3TW1 A;  1WVH A;  4GXB A;  2X18 A;  2D10 A;  4GPT B;  2GCL A;  1ISN A;  2Q13 A;  2QKL A;  3KRW A;  4GMV A;  4IFS A;  1FAO A;  1ZVR A;  2Z13 A;  3ULB A;  2UVM A;  4IOY X;  4EMO A;  4HSI A;  3PP2 A;  1MAI A;  1EAZ A;  4HAU B;  1BTN A;  1SGH A;  2K2U A;  5EFX A;  1FGZ A;  2GS0 A;  2RSG A;  1V5P A;  2YS1 A;  5JHH A;  2OQB A;  1MIZ B;  1OMW A;  2KIE A;  2COD A;  4YON A;  5D3Y A;  5FI0 A;  2Y8F A;  1DYN A;  4BBK A;  3M1I B;  1U5D A;  1KZG A;  3PG7 A;  4CSQ A;  1H10 A;  4HB4 B;  4D0N B;  1AQC A;  2COF A;  2N0Y A;  2AEH A;  1V5U A;  2ELB A;  3KZ1 A;  2DYN A;  4HB3 B;  4KAX B;  5CLL B;  2Z0O A;  2DX1 A;  2DA0 A;  2RUK B;  1P6S A;  4P7I A;  4EKU A;  3AU5 A;  4MT7 A;  2KCJ A;  1KZ7 A;  2MFQ A;  4OSN A;  2DFK A;  2YT0 A;  1DDM A;  4KHB B;  2RNR B;  2Y8G A;  4Y94 A;  2LOX A;  2EMS A;  5DH9 B;  3HSA A;  3D8D A;  3QWM A;  3UZT A;  1UPQ A;  3HW2 B;  2KR0 A;  2M14 A;  4F7U P;  1U5E A;  2Z0P A;  4DX9 0;  1WJ1 A;  3U7D A;  1X86 A;  2K8E A;  4GNK B;  2Z0Q A;  3TVV A;  1OY2 A;  4HAX B;  4NY0 A;  3SUZ A;  5IRS A;  4K17 A;  2QKM A;  2ROZ B;  2D9Z A;  5LOP B;  1P5T A;  3TO1 A;  2FJL A;  1M7E A;  1Y19 B;  3QBV B;  2DHI A;  5D3V A;  2NBV A;  1Z87 A;  1K5G B;  1Y5O A;  4KVG B;  2EC1 A;  4A6F B;  1ZSQ A;  3DXD A;  3SV1 A;  3F0W A;  2YVC A;  4GN1 A;  3WYF B;  3BJI A;  4F7H A;  2CY5 A;  3KY9 A;  5DHF B;  1GC6 A;  1UNP A;  2ZKM X;  4ZRI A;  4ZRK A;  1LB1 A;  3PZD A;  3DXC A;  3ULC A;  1WJM A;  5HE1 A;  2L1C A;  4QXA B;  4HHV A;  3ZDT A;  3TCA A;  1XX0 A;  4A6F A;  2R09 A;  3A98 B;  1KI1 B;  3NWA A;  1X11 A;  2YT2 A;  1TXD A;  2Z14 A;  2AL6 A;  2KUP A;  2IYB A;  2H7E A;  4D6W A;  3CIK A;  1RRP B;  2KIG A;  2H7D A;  3N7C A;  5DI9 B;  5KCV A;  2J59 M;  3V5W A;  4Z2N A;  3FM8 C;  2CY4 A;  2D9X A;  4A6K A;  2OTX A;  1LW3 A;  2I1J A;  1U2B A;  1ZC4 B;  5C16 A;  1MI1 A;  5C79 A;  3B77 A;  3NWD A;  2HTH B;  4HDQ A;  3ODW A;  1PFJ A;  2HE7 A;  4MY6 A;  2LKO A;  4TYZ A;  2EMT A;  2DLW A;  2E2X A;  4QJ3 B;  3U8Z A;  1PMS A;  2W2X D;  2RLO A;  1ZC3 B;  2RRF A;  5D3X A;  2Y7B A;  5JP4 A;  1RJ2 A;  2K2J A;  1ZYI A;  2Z4D A;  1GC7 A;  4XWX A;  1IRS A;  1DRO A;  1K5D B;  2ROV A;  1U29 A;  2P0H A;  3PVU A;  4HAZ B;  1OQN A;  2Z59 A;  3DXE A;  1DDV A;  2RVB B;  5JHG A;  1J0W A;  2BCJ A;  3F5R A;  2FJU B;  3NSU A;  3PSC A;  2P0F A;  1QC6 A;  3MDB C;  2J0K A;  4HAW B;  1EGX A;  3BIN A;  3NW8 A;  2DN6 A;  3FVC A;  2G35 A;  1I2H A;  4KHB A;  3P6A A;  4K2O A;  1XR0 B;  3GYO A;  2KUQ A;  5LG4 B;  2P0D A;  3RCP A;  3G9W A;  1V61 A;  1WGU A;  4HAY B;  1FHW A;  1GG3 A;  2DX5 A;  3HK0 A;  3TFM A;  2YF0 A;  3T06 A;  2VRW B;  1NI2 A;  4L6E A;  2JP2 A;  4Z2M B;  2CRF A;  2NZ8 B;  5LON B;  1UNQ A;  1W1H A;  2YS5 A;  3ODO A;  5KQ4 A;  1U27 A;  4K81 A;  3QIJ A;  2YS3 A;  3HIE A;  3OAN A;  1BTK A;  4B6H A;  2W2X C;  1I7A A;  1TQZ A;  1MKE A;  1MK9 B;  4CHM A;  2KGX B;  3X23 A;  3IVF A;  5D27 A;  1WI1 A;  2R2Y A;  3NWF A;  1FHX A;  4HB2 B;  2V76 A;  3HQC A;  2XQN M;  2CAY A; 
#chains in the Genus database with same CATH homology
 2LYD A;  1UPR A;  1FOE A;  2GCJ A;  3A8P A;  4A6H A;  1SHC A;  2D9Y A;  3ZVR A;  1MPH A;  5D3W A;  2DYQ A;  2MWN B;  2DKP A;  3D8F A;  1EF1 A;  3P7Z A;  5HE0 A;  2DHJ A;  4CHJ A;  5HE2 A;  2UZR A;  1XKE A;  1J19 A;  1X05 A;  1NTY A;  2DKQ A;  4HDO A;  4C0A A;  1FHO A;  1U5F A;  5C5B B;  3VOQ A;  3SYX A;  3PVL A;  3O96 A;  4PNK A;  5GOW B;  1MIX A;  1WGQ A;  1X1G A;  2UZS A;  2ELA A;  1H4R A;  1UNR A;  2I1K A;  4HAV B;  5C6R A;  1N3H A;  1XOD A;  1E5W A;  5CLQ B;  2LG1 A;  4GZU A;  2J0M A;  4KHO A;  2I5F A;  1MK7 B;  3A8Q A;  1X1F A;  4F7G A;  5C5B A;  4WSF A;  1BAK A;  2YT1 A;  2COC A;  2IFS A;  4A5K A;  1DDW A;  2YRY A;  1WG7 A;  1W1G A;  1V5M A;  4HB0 B;  2W2W A;  5DIF B;  2D4Q A;  3FEH A;  3MPX A;  4H8S A;  1P3R A;  4WVF B;  4ZRJ A;  2LUL A;  2D9V A;  3KSY A;  4K2P A;  5J3Y A;  1FGY A;  3LJU X;  1PLS A;  1EVH A;  2P8V A;  4TKN A;  2M38 A;  1QQG A;  5KQ1 A;  1UEF A;  2DTC A;  3AU4 A;  3CXB B;  4GMX B;  1U5G A;  5L81 A;  4DX8 A;  2I5C A;  2COA A;  1W1D A;  1V89 A;  3SNH A;  2NMB A;  5DHA B;  1AWE A;  2N23 A;  3VIA A;  5FI1 A;  4CYE A;  3D8E A;  2YSZ A;  3ML4 A;  4EJN A;  2J0J A;  4WJ7 A;  4DBB A;  2EJ8 A;  3FSS A;  2VKI A;  1V88 A;  4PQ0 A;  1TJ6 A;  3KRX A;  5HE3 A;  4KHA A;  1FB8 A;  3WA0 A;  2MKR A;  5J3Q A;  2LOZ A;  2R0D A;  3PVW A;  2ADZ A;  2D11 A;  2L2I A;  2MDX A;  1ZM0 A;  2PZ1 A;  2RGN B;  2GJY A;  4HAT B;  2D9W A;  2K00 A;  1NU2 A;  3ODX A;  3PEG A;  4NSW A;  1XCG A;  2VSZ A;  4DXA B;  3GYP A;  1XD4 A;  1Q67 A;  5J3T A;  2D2Q A;  5JLJ B;  1B55 A;  4YL8 A;  1M7R A;  2DHK A;  3AJ4 A;  4MK0 A;  1BWN A;  1DBH A;  2ZPY A;  4IAP A;  1NTV A;  3SO6 A;  3TW1 A;  1WVH A;  4GXB A;  2X18 A;  2D10 A;  4GPT B;  2GCL A;  1ISN A;  2Q13 A;  2QKL A;  3KRW A;  4GMV A;  4IFS A;  1FAO A;  1ZVR A;  3ULB A;  2UVM A;  4IOY X;  4EMO A;  3PP2 A;  1MAI A;  1EAZ A;  4HAU B;  1BTN A;  1SGH A;  2K2U A;  5EFX A;  1FGZ A;  2GS0 A;  2RSG A;  1V5P A;  2YS1 A;  5JHH A;  2OQB A;  1MIZ B;  1OMW A;  2COD A;  4YON A;  5D3Y A;  5FI0 A;  2Y8F A;  1DYN A;  4BBK A;  3M1I B;  1U5D A;  1KZG A;  3PG7 A;  1H10 A;  4HB4 B;  4D0N B;  1AQC A;  2COF A;  2N0Y A;  2AEH A;  1V5U A;  2ELB A;  3KZ1 A;  2DYN A;  4HB3 B;  4KAX B;  5CLL B;  2Z0O A;  2DX1 A;  2DA0 A;  2RUK B;  1P6S A;  4P7I A;  4EKU A;  3AU5 A;  4MT7 A;  2KCJ A;  1KZ7 A;  2MFQ A;  2DFK A;  2YT0 A;  1DDM A;  4KHB B;  2RNR B;  2Y8G A;  4Y94 A;  2LOX A;  2EMS A;  5DH9 B;  3D8D A;  3QWM A;  3UZT A;  1UPQ A;  3HW2 B;  2M14 A;  4F7U P;  1U5E A;  2Z0P A;  4DX9 0;  1WJ1 A;  3U7D A;  1X86 A;  2Z0Q A;  3TVV A;  1OY2 A;  4HAX B;  4NY0 A;  3SUZ A;  4K17 A;  2QKM A;  2ROZ B;  2D9Z A;  5LOP B;  1P5T A;  3TO1 A;  2FJL A;  1M7E A;  1Y19 B;  3QBV B;  2DHI A;  5D3V A;  1Z87 A;  1K5G B;  1Y5O A;  4KVG B;  2EC1 A;  4A6F B;  1ZSQ A;  3DXD A;  3SV1 A;  3F0W A;  2YVC A;  4GN1 A;  3WYF B;  3BJI A;  4F7H A;  2CY5 A;  3KY9 A;  5DHF B;  1GC6 A;  1UNP A;  4ZRI A;  4ZRK A;  1LB1 A;  3PZD A;  3DXC A;  3ULC A;  1WJM A;  5HE1 A;  2L1C A;  4HHV A;  3ZDT A;  3TCA A;  1XX0 A;  4A6F A;  2R09 A;  3A98 B;  1KI1 B;  1X11 A;  1TXD A;  2AL6 A;  2KUP A;  2IYB A;  2H7E A;  3CIK A;  1RRP B;  2H7D A;  3N7C A;  5DI9 B;  5KCV A;  2J59 M;  3V5W A;  4Z2N A;  3FM8 C;  2CY4 A;  2D9X A;  4A6K A;  2OTX A;  1LW3 A;  2I1J A;  1U2B A;  1ZC4 B;  5C16 A;  5C79 A;  2HTH B;  4HDQ A;  3ODW A;  1PFJ A;  2HE7 A;  4MY6 A;  2LKO A;  4TYZ A;  2EMT A;  2DLW A;  2E2X A;  3U8Z A;  1PMS A;  2W2X D;  2RLO A;  1ZC3 B;  5JP4 A;  5D3X A;  2Y7B A;  1RJ2 A;  2K2J A;  4XWX A;  1GC7 A;  1IRS A;  1DRO A;  1K5D B;  2ROV A;  1U29 A;  2P0H A;  3PVU A;  4HAZ B;  1OQN A;  3DXE A;  1DDV A;  2RVB B;  5JHG A;  1J0W A;  2BCJ A;  3F5R A;  3NSU A;  3PSC A;  2P0F A;  1QC6 A;  3MDB C;  2J0K A;  4HAW B;  1EGX A;  3BIN A;  2DN6 A;  2G35 A;  1I2H A;  3P6A A;  4K2O A;  1XR0 B;  3GYO A;  2P0D A;  3RCP A;  3G9W A;  1V61 A;  1WGU A;  4HAY B;  1FHW A;  1GG3 A;  2DX5 A;  3HK0 A;  3TFM A;  2YF0 A;  3T06 A;  2VRW B;  1NI2 A;  4L6E A;  2JP2 A;  4Z2M B;  2CRF A;  2NZ8 B;  5LON B;  1UNQ A;  1W1H A;  2YS5 A;  3ODO A;  5KQ4 A;  1U27 A;  4K81 A;  3QIJ A;  2YS3 A;  3OAN A;  1BTK A;  4B6H A;  2W2X C;  1I7A A;  1TQZ A;  1MKE A;  1MK9 B;  4CHM A;  2KGX B;  3X23 A;  3IVF A;  5D27 A;  1WI1 A;  1FHX A;  4HB2 B;  2V76 A;  3HQC A;  2XQN M;  2CAY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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