4HB0B

Crystal structure of crm1 inhibitor leptomycin b in complex with crm1(k541q,k542q,r543s,k545q,k548q,k579q)-ran-ranbp1
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
121
structure length
121
Chain Sequence
EEDEEVLYKVRAKLFRFDKDAKEWKERGTGDCKFLKNKKTNKVRILMRRDKTLKICANHIIAPEYTLKPNVGSDRSWVYACTADIAEGEAEAFTFAIRFGSKENADKFKEEFEKAQEINKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
pubmed doi rcsb
molecule tags Protein transport/antibiotic
source organism Homo sapiens
molecule keywords GTP-binding nuclear protein Ran
total genus 36
structure length 121
sequence length 121
ec nomenclature
pdb deposition date 2012-09-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00638 Ran_BP1 RanBP1 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 4hb0B00
4HAZB 2D11A 1DBHA 1NI2A 3MPXA 4XWXA 1DDWA 2UZSA 5DIFB 4K17A 5DI9B 3HK0A 3ULCA 2EJ8A 2YS3A 1KZGA 1J19A 2CODA 2YRYA 1NTYA 3ODOA 1Y19B 3A8QA 4HAYB 2BCJA 3ZVRA 3GYOA 2DLWA 1UEFA 2UVMA 1W1GA 3P7ZA 1UNPA 2D2QA 1U5EA 1UPQA 4ZRKA 1MAIA 2I1JA 5C5BB 2YS1A 1V61A 1WJ1A 4KHAA 5D3XA 4TKNA 1RRPB 5FI0A 1V88A 1PFJA 1P5TA 4PQ0A 1FHXA 1WJMA 2GCJA 2LYDA 3V5WA 5D3YA 4MT7A 2H7DA 1XODA 2GCLA 2DFKA 4GMXB 2XQNM 1DYNA 2RLOA 3SYXA 2E2XA 1WVHA 3A98B 2R09A 5KQ1A 2MKRA 1E5WA 2RSGA 1ZC3B 4D0NB 2D4QA 4HAXB 1QC6A 4GMVA 2PZ1A 5J3TA 1FGYA 1P3RA 2Y7BA 3TO1A 4EJNA 2L1CA 4CYEA 1U5GA 5FI1A 1ISNA 3O96A 3D8FA 2NZ8B 5C6RA 3M1IB 5LOPB 2KCJA 2W2WA 1FGZA 3PVLA 1XR0B 1Z87A 2DHKA 3TCAA 5D3VA 2QKMA 2Z0PA 3SO6A 2W2XD 2YF0A 2K00A 3F0WA 4WJ7A 4DX8A 2NMBA 2I5FA 4DBBA 3CIKA 1B55A 2AL6A 1WGQA 4GN1A 4IAPA 2J0JA 3F5RA 4HB3B 2H7EA 5JLJB 2YSZA 4WVFB 2K2UA 3FSSA 1X1FA 4A6FA 1UPRA 3KSYA 2P0DA 3ODXA 1DDMA 1QQGA 4NSWA 2DX5A 4A6KA 1PMSA 1WG7A 3CXBB 1OQNA 4YL8A 4B6HA 2GJYA 1EGXA 3TFMA 4MK0A 2CY5A 3NSUA 2AEHA 4NY0A 2COAA 5DH9B 1BTNA 3U7DA 2D9YA 2I1KA 3QWMA 1MK9B 1V5MA 4WSFA 3D8DA 1U5DA 2HE7A 3SV1A 3QBVB 1ZSQA 3WA0A 1FOEA 2D9VA 2EMSA 3ML4A 5DHFB 1X11A 4MY6A 5HE1A 4GXBA 4HDQA 2MWNB 3U8ZA 5DHAB 2RVBB 2IYBA 2DKPA 4Y94A 3VIAA 4DXAB 4BBKA 1M7EA 3RCPA 2D9WA 2I5CA 1AQCA 3ZDTA 3A8PA 3AU5A 3DXDA 5D27A 2D9ZA 1J0WA 4KVGB 2P8VA 4HB2B 1OMWA 2J0KA 2ROZB 2IFSA 5JHGA 1V5PA 1TXDA 5D3WA 2Q13A 3D8EA 2DTCA 2FJLA 2N23A 2RUKB 4PNKA 1DDVA 5LONB 1ZM0A 2COCA 3KRWA 3OANA 4A6HA 1MPHA 1NTVA 2R0DA 1W1DA 5J3YA 3PEGA 1WI1A 1V5UA 1TJ6A 5C79A 2YT0A 3QIJA 1N3HA 2CY4A 3T06A 1PLSA 4KHOA 3ULBA 1MIXA 1XX0A 4A5KA 1U27A 2YS5A 1FAOA 4DX90 1FHWA 1OY2A 4L6EA 1GG3A 1Y5OA 1GC6A 2LOZA 2OQBA 1WGUA 1H10A 5CLLB 2K2JA 1KZ7A 3KZ1A 1M7RA 1XD4A 3ODWA 1FB8A 1DROA 3UZTA 3PVUA 1UNQA 2L2IA 5HE0A 2VSZA 3VOQA 3HW2B 2Y8FA 4K2OA 3KRXA 2KGXB 2HTHB 1K5DB 4HDOA 2DKQA 2CAYA 2ROVA 3PVWA 3HQCA 5EFXA 1ZVRA 4C0AA 1BWNA 1XKEA 3BINA 4K2PA 3BJIA 2Z0OA 2J0MA 3PSCA 2W2XC 4A6FB 1IRSA 2LOXA 5J3QA 2EC1A 4CHJA 2M14A 1X1GA 1GC7A 3TVVA 5GOWB 3PG7A 3N7CA 1SHCA 2OTXA 2N0YA 3FEHA 2P0FA 5C16A 2VRWB 3GYPA 2DA0A 4HHVA 1Q67A 2RGNB 3DXEA 4IOYX 1UNRA 4K81A 4EKUA 2JP2A 5C5BA 3AU4A 1ZC4B 2G35A 2QKLA 2RNRB 5HE2A 3AJ4A 4GPTB 3WYFB 1MKEA 2M38A 1SGHA 3P6AA 1KI1B 2DHIA 1RJ2A 1XCGA 2LKOA 4EMOA 1H4RA 2ELAA 2D10A 2MDXA 3MDBC 4HAVB 3PP2A 4Z2MB 4F7HA 1MIZB 2GS0A 5JHHA 1EF1A 1LB1A 2V76A 4CHMA 4HAUB 2EMTA 4YONA 1X05A 1V89A 3LJUX 5L81A 1I2HA 2COFA 1LW3A 2LULA 4KAXB 2DHJA 1BAKA 5KQ4A 2J59M 1U5FA 5KCVA 2YT1A 4P7IA 1BTKA 2DYNA 3SNHA 5HE3A 1NU2A 1FHOA 4IFSA 3DXCA 3X23A 1I7AA 2VKIA 5JP4A 1U2BA 1EVHA 2Z0QA 4HAWB 4H8SA 3TW1A 4TYZA 3FM8C 1W1HA 2KUPA 1P6SA 1X86A 4ZRJA 1TQZA 4ZRIA 2DYQA 4HB4B 3SUZA 4Z2NA 2ELBA 4F7GA 1U29A 2CRFA 4HB0B 2YVCA 2ADZA 5CLQB 2MFQA 2ZPYA 3PZDA 4GZUA 1AWEA 3G9WA 3IVFA 2LG1A 1MK7B 4F7UP 1K5GB 2X18A 2UZRA 2P0HA 4HATB 2D9XA 2DX1A 4KHBB 1EAZA 3KY9A 2DN6A 2Y8GA
chains in the Genus database with same CATH superfamily
4HAZB 2D11A 1DBHA 1NI2A 3MPXA 4XWXA 4QJ3B 1DDWA 3DCXA 2UZSA 5DIFB 2ZKMX 4K17A 5DI9B 3HK0A 3ULCA 2EJ8A 2YS3A 1KZGA 1J19A 2CODA 2YRYA 1NTYA 4OSNA 2NBVA 3ODOA 1Y19B 3A8QA 4HAYB 2BCJA 3ZVRA 3GYOA 2DLWA 1UEFA 2UVMA 1W1GA 3P7ZA 1UNPA 2D2QA 1U5EA 1UPQA 4ZRKA 1MAIA 2I1JA 5C5BB 2YS1A 1V61A 1WJ1A 4KHAA 4QXAB 5D3XA 4TKNA 1RRPB 5FI0A 1V88A 1PFJA 1P5TA 4PQ0A 1FHXA 1WJMA 2GCJA 4QJ4B 2LYDA 3V5WA 5D3YA 4MT7A 2H7DA 1XODA 2GCLA 2DFKA 4GMXB 2K8EA 1T77A 2XQNM 1DYNA 2RLOA 3SYXA 2E2XA 1WVHA 3A98B 2R09A 5KQ1A 2MKRA 1E5WA 2RSGA 1ZC3B 4D0NB 2R2YA 2D4QA 4HAXB 1QC6A 4GMVA 4OT1A 2PZ1A 5J3TA 1FGYA 1P3RA 2Y7BA 3TO1A 4EJNA 2L1CA 4CYEA 1U5GA 5FI1A 1ISNA 3O96A 3D8FA 2NZ8B 5C6RA 3M1IB 5LOPB 2KCJA 2W2WA 1FGZA 3PVLA 1XR0B 1Z87A 2DHKA 3TCAA 5D3VA 2QKMA 2Z0PA 3SO6A 2W2XD 2YF0A 2K00A 2KIEA 3F0WA 4WJ7A 4DX8A 2NMBA 2I5FA 4DBBA 3CIKA 1B55A 2AL6A 1WGQA 4GN1A 4IAPA 3OHMB 2J0JA 3F5RA 4HB3B 2H7EA 5JLJB 2YSZA 4WVFB 2K2UA 3NW8A 3FSSA 1X1FA 4A6FA 1UPRA 3KSYA 2P0DA 3ODXA 1DDMA 1QQGA 4NSWA 2DX5A 4A6KA 1PMSA 1WG7A 3CXBB 2Z14A 1OQNA 4YL8A 4B6HA 2GJYA 1EGXA 3TFMA 4L1RA 4MK0A 2CY5A 3NSUA 2AEHA 4NY0A 2Z13A 2COAA 5DH9B 1BTNA 3U7DA 2D9YA 2I1KA 3A58A 3QWMA 1MK9B 1V5MA 4WSFA 3D8DA 1U5DA 2HE7A 3SV1A 3NWAA 3QBVB 1ZSQA 3WA0A 1FOEA 2D9VA 3HIEA 2EMSA 3ML4A 4GOUA 5DHFB 1X11A 4MY6A 5HE1A 3HSAA 3NWFA 5I2SA 4GXBA 4HDQA 2MWNB 3U8ZA 5DHAB 2RVBB 2IYBA 2DKPA 4Y94A 3VIAA 4DXAB 4BBKA 1M7EA 3RCPA 2D9WA 2I5CA 1AQCA 3ZDTA 3A8PA 3AU5A 3DXDA 5I2MA 5D27A 2D9ZA 1J0WA 4KVGB 2P8VA 4HB2B 1OMWA 2J0KA 2ROZB 2IFSA 5JHGA 1V5PA 1TXDA 5D3WA 2Q13A 3D8EA 2DTCA 2FJUB 2FJLA 2KUQA 2N23A 2RUKB 4PNKA 1DDVA 5LONB 1ZM0A 2COCA 3KRWA 3OANA 4A6HA 1MPHA 1NTVA 2R0DA 1W1DA 5J3YA 3PEGA 1WI1A 3B77A 2KR0A 1V5UA 1TJ6A 5C79A 2YT0A 3QIJA 1N3HA 1MI1A 2CY4A 3T06A 1PLSA 4KHOA 3ULBA 1MIXA 1XX0A 4A5KA 4GNKB 1U27A 2YS5A 1FAOA 4DX90 1FHWA 1OY2A 4L6EA 1GG3A 1Y5OA 1GC6A 2LOZA 2OQBA 1WGUA 1H10A 5CLLB 2K2JA 1KZ7A 3KZ1A 1M7RA 1XD4A 3ODWA 1FB8A 1DROA 5LG4B 3UZTA 3PVUA 1UNQA 2L2IA 5HE0A 2VSZA 3VOQA 3HW2B 2Y8FA 4K2OA 1ZYIA 2K49A 2KGXB 3KRXA 2HTHB 1K5DB 4HDOA 2DKQA 2CAYA 2ROVA 3PVWA 3HQCA 5EFXA 1ZVRA 4C0AA 1BWNA 2Z4DA 1XKEA 3BINA 4K2PA 2Z59A 3BJIA 2Z0OA 2J0MA 3PSCA 2W2XC 4A6FB 1IRSA 2LOXA 5J3QA 2EC1A 4CHJA 2M14A 1X1GA 1GC7A 3TVVA 5GOWB 3PG7A 3N7CA 1SHCA 2OTXA 2N0YA 3FEHA 2P0FA 5C16A 2RRFA 2VRWB 3GYPA 2DA0A 4HHVA 1Q67A 2RGNB 3DXEA 4IOYX 1UNRA 4K81A 4EKUA 2JP2A 5C5BA 3AU4A 1ZC4B 2G35A 2QKLA 2RNRB 5HE2A 3AJ4A 4GPTB 3WYFB 1MKEA 3U12A 2M38A 1SGHA 3P6AA 1KI1B 2DHIA 1RJ2A 1XCGA 2LKOA 4EMOA 1H4RA 2ELAA 2D10A 2MDXA 3MDBC 4HAVB 3PP2A 4Z2MB 4F7HA 1MIZB 2GS0A 5JHHA 1EF1A 1LB1A 4CSQA 2V76A 4HSIA 4CHMA 2YT2A 4HAUB 2EMTA 4YONA 1X05A 1V89A 3LJUX 5L81A 1I2HA 2COFA 1LW3A 4QJ5B 2LULA 4KAXB 2DHJA 3FVCA 1BAKA 5KQ4A 2GUMA 2J59M 1U5FA 5KCVA 2YT1A 4P7IA 1BTKA 2KIGA 2DYNA 3SNHA 5HE3A 1NU2A 1FHOA 4IFSA 3DXCA 3X23A 1I7AA 2VKIA 5JP4A 1U2BA 1EVHA 2Z0QA 4HAWB 4DIXA 4H8SA 3TW1A 4TYZA 3FM8C 5IRSA 1W1HA 2KUPA 1P6SA 1X86A 4ZRJA 1TQZA 4ZRIA 2DYQA 4HB4B 3SUZA 4Z2NA 2ELBA 4F7GA 1U29A 2CRFA 4HB0B 2YVCA 2ADZA 5CLQB 2MFQA 2ZPYA 3PZDA 4GZUA 4KHBA 3NWDA 1AWEA 3G9WA 2LG1A 3IVFA 1MK7B 4F7UP 1K5GB 4D6WA 2X18A 2UZRA 2P0HA 4HATB 2D9XA 2DX1A 4KHBB 1EAZA 3KY9A 5M4YB 2DN6A 2Y8GA
chains in the Genus database with same CATH topology
4HAZB 2D11A 1DBHA 1NI2A 3MPXA 4XWXA 1DDWA 2UZSA 5DIFB 4K17A 5DI9B 3HK0A 3ULCA 2EJ8A 2YS3A 1KZGA 1J19A 2CODA 2YRYA 1NTYA 3ODOA 1Y19B 3A8QA 4HAYB 2BCJA 3ZVRA 3GYOA 2DLWA 1UEFA 2UVMA 1W1GA 3P7ZA 1UNPA 2D2QA 1U5EA 1UPQA 4ZRKA 1MAIA 2I1JA 5C5BB 2YS1A 1V61A 1WJ1A 4KHAA 5D3XA 4TKNA 1RRPB 5FI0A 1V88A 1PFJA 1P5TA 4PQ0A 1FHXA 1WJMA 2GCJA 2LYDA 3V5WA 5D3YA 4MT7A 2H7DA 1XODA 2GCLA 2DFKA 4GMXB 2XQNM 1DYNA 2RLOA 3SYXA 2E2XA 1WVHA 3A98B 2R09A 5KQ1A 2MKRA 1E5WA 2RSGA 1ZC3B 4D0NB 2D4QA 4HAXB 1QC6A 4GMVA 2PZ1A 5J3TA 1FGYA 1P3RA 2Y7BA 3TO1A 4EJNA 2L1CA 4CYEA 1U5GA 5FI1A 1ISNA 3O96A 3D8FA 2NZ8B 5C6RA 3M1IB 5LOPB 2KCJA 2W2WA 1FGZA 3PVLA 1XR0B 1Z87A 2DHKA 3TCAA 5D3VA 2QKMA 2Z0PA 3SO6A 2W2XD 2YF0A 2K00A 3F0WA 4WJ7A 4DX8A 2NMBA 2I5FA 4DBBA 3CIKA 1B55A 2AL6A 1WGQA 4GN1A 4IAPA 2J0JA 3F5RA 4HB3B 2H7EA 5JLJB 2YSZA 4WVFB 2K2UA 3FSSA 1X1FA 4A6FA 1UPRA 3KSYA 2P0DA 3ODXA 1DDMA 1QQGA 4NSWA 2DX5A 4A6KA 1PMSA 1WG7A 3CXBB 1OQNA 4YL8A 4B6HA 2GJYA 1EGXA 3TFMA 4MK0A 2CY5A 3NSUA 2AEHA 4NY0A 2COAA 5DH9B 1BTNA 3U7DA 2D9YA 2I1KA 3QWMA 1MK9B 1V5MA 4WSFA 3D8DA 1U5DA 2HE7A 3SV1A 3QBVB 1ZSQA 3WA0A 1FOEA 2D9VA 2EMSA 3ML4A 5DHFB 1X11A 4MY6A 5HE1A 4GXBA 4HDQA 2MWNB 3U8ZA 5DHAB 2RVBB 2IYBA 2DKPA 4Y94A 3VIAA 4DXAB 4BBKA 1M7EA 3RCPA 2D9WA 2I5CA 1AQCA 3ZDTA 3A8PA 3AU5A 3DXDA 5D27A 2D9ZA 1J0WA 4KVGB 2P8VA 4HB2B 1OMWA 2J0KA 2ROZB 2IFSA 5JHGA 1V5PA 1TXDA 5D3WA 2Q13A 3D8EA 2DTCA 2FJLA 2N23A 2RUKB 4PNKA 1DDVA 5LONB 1ZM0A 2COCA 3KRWA 3OANA 4A6HA 1MPHA 1NTVA 2R0DA 1W1DA 5J3YA 3PEGA 1WI1A 1V5UA 1TJ6A 5C79A 2YT0A 3QIJA 1N3HA 2CY4A 3T06A 1PLSA 4KHOA 3ULBA 1MIXA 1XX0A 4A5KA 1U27A 2YS5A 1FAOA 4DX90 1FHWA 1OY2A 4L6EA 1GG3A 1Y5OA 1GC6A 2LOZA 2OQBA 1WGUA 1H10A 5CLLB 2K2JA 1KZ7A 3KZ1A 1M7RA 1XD4A 3ODWA 1FB8A 1DROA 3UZTA 3PVUA 1UNQA 2L2IA 5HE0A 2VSZA 3VOQA 3HW2B 2Y8FA 4K2OA 3KRXA 2KGXB 2HTHB 1K5DB 4HDOA 2DKQA 2CAYA 2ROVA 3PVWA 3HQCA 5EFXA 1ZVRA 4C0AA 1BWNA 1XKEA 3BINA 4K2PA 3BJIA 2Z0OA 2J0MA 3PSCA 2W2XC 4A6FB 1IRSA 2LOXA 5J3QA 2EC1A 4CHJA 2M14A 1X1GA 1GC7A 3TVVA 5GOWB 3PG7A 3N7CA 1SHCA 2OTXA 2N0YA 3FEHA 2P0FA 5C16A 2VRWB 3GYPA 2DA0A 4HHVA 1Q67A 2RGNB 3DXEA 4IOYX 1UNRA 4K81A 4EKUA 2JP2A 5C5BA 3AU4A 1ZC4B 2G35A 2QKLA 2RNRB 5HE2A 3AJ4A 4GPTB 3WYFB 1MKEA 2M38A 1SGHA 3P6AA 1KI1B 2DHIA 1RJ2A 1XCGA 2LKOA 4EMOA 1H4RA 2ELAA 2D10A 2MDXA 3MDBC 4HAVB 3PP2A 4Z2MB 4F7HA 1MIZB 2GS0A 5JHHA 1EF1A 1LB1A 2V76A 4CHMA 4HAUB 2EMTA 4YONA 1X05A 1V89A 3LJUX 5L81A 1I2HA 2COFA 1LW3A 2LULA 4KAXB 2DHJA 1BAKA 5KQ4A 2J59M 1U5FA 5KCVA 2YT1A 4P7IA 1BTKA 2DYNA 3SNHA 5HE3A 1NU2A 1FHOA 4IFSA 3DXCA 3X23A 1I7AA 2VKIA 5JP4A 1U2BA 1EVHA 2Z0QA 4HAWB 4H8SA 3TW1A 4TYZA 3FM8C 1W1HA 2KUPA 1P6SA 1X86A 4ZRJA 1TQZA 4ZRIA 2DYQA 4HB4B 3SUZA 4Z2NA 2ELBA 4F7GA 1U29A 2CRFA 4HB0B 2YVCA 2ADZA 5CLQB 2MFQA 2ZPYA 3PZDA 4GZUA 1AWEA 3G9WA 3IVFA 2LG1A 1MK7B 4F7UP 1K5GB 2X18A 2UZRA 2P0HA 4HATB 2D9XA 2DX1A 4KHBB 1EAZA 3KY9A 2DN6A 2Y8GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HAZ B;  2D11 A;  1DBH A;  1NI2 A;  3MPX A;  4XWX A;  1DDW A;  2UZS A;  5DIF B;  4K17 A;  5DI9 B;  3HK0 A;  3ULC A;  2EJ8 A;  2YS3 A;  1KZG A;  1J19 A;  2COD A;  2YRY A;  1NTY A;  3ODO A;  1Y19 B;  3A8Q A;  4HAY B;  2BCJ A;  3ZVR A;  3GYO A;  2DLW A;  1UEF A;  2UVM A;  1W1G A;  3P7Z A;  1UNP A;  2D2Q A;  1U5E A;  1UPQ A;  4ZRK A;  1MAI A;  2I1J A;  5C5B B;  2YS1 A;  1V61 A;  1WJ1 A;  4KHA A;  5D3X A;  4TKN A;  1RRP B;  5FI0 A;  1V88 A;  1PFJ A;  1P5T A;  4PQ0 A;  1FHX A;  1WJM A;  2GCJ A;  2LYD A;  3V5W A;  5D3Y A;  4MT7 A;  2H7D A;  1XOD A;  2GCL A;  2DFK A;  4GMX B;  2XQN M;  1DYN A;  2RLO A;  3SYX A;  2E2X A;  1WVH A;  3A98 B;  2R09 A;  5KQ1 A;  2MKR A;  1E5W A;  2RSG A;  1ZC3 B;  4D0N B;  2D4Q A;  4HAX B;  1QC6 A;  4GMV A;  2PZ1 A;  5J3T A;  1FGY A;  1P3R A;  2Y7B A;  3TO1 A;  4EJN A;  2L1C A;  4CYE A;  1U5G A;  5FI1 A;  1ISN A;  3O96 A;  3D8F A;  2NZ8 B;  5C6R A;  3M1I B;  5LOP B;  2KCJ A;  2W2W A;  1FGZ A;  3PVL A;  1XR0 B;  1Z87 A;  2DHK A;  3TCA A;  5D3V A;  2QKM A;  2Z0P A;  3SO6 A;  2W2X D;  2YF0 A;  2K00 A;  3F0W A;  4WJ7 A;  4DX8 A;  2NMB A;  2I5F A;  4DBB A;  3CIK A;  1B55 A;  2AL6 A;  1WGQ A;  4GN1 A;  4IAP A;  2J0J A;  3F5R A;  4HB3 B;  2H7E A;  5JLJ B;  2YSZ A;  4WVF B;  2K2U A;  3FSS A;  1X1F A;  4A6F A;  1UPR A;  3KSY A;  2P0D A;  3ODX A;  1DDM A;  1QQG A;  4NSW A;  2DX5 A;  4A6K A;  1PMS A;  1WG7 A;  3CXB B;  1OQN A;  4YL8 A;  4B6H A;  2GJY A;  1EGX A;  3TFM A;  4MK0 A;  2CY5 A;  3NSU A;  2AEH A;  4NY0 A;  2COA A;  5DH9 B;  1BTN A;  3U7D A;  2D9Y A;  2I1K A;  3QWM A;  1MK9 B;  1V5M A;  4WSF A;  3D8D A;  1U5D A;  2HE7 A;  3SV1 A;  3QBV B;  1ZSQ A;  3WA0 A;  1FOE A;  2D9V A;  2EMS A;  3ML4 A;  5DHF B;  1X11 A;  4MY6 A;  5HE1 A;  4GXB A;  4HDQ A;  2MWN B;  3U8Z A;  5DHA B;  2RVB B;  2IYB A;  2DKP A;  4Y94 A;  3VIA A;  4DXA B;  4BBK A;  1M7E A;  3RCP A;  2D9W A;  2I5C A;  1AQC A;  3ZDT A;  3A8P A;  3AU5 A;  3DXD A;  5D27 A;  2D9Z A;  1J0W A;  4KVG B;  2P8V A;  4HB2 B;  1OMW A;  2J0K A;  2ROZ B;  2IFS A;  5JHG A;  1V5P A;  1TXD A;  5D3W A;  2Q13 A;  3D8E A;  2DTC A;  2FJL A;  2N23 A;  2RUK B;  4PNK A;  1DDV A;  5LON B;  1ZM0 A;  2COC A;  3KRW A;  3OAN A;  4A6H A;  1MPH A;  1NTV A;  2R0D A;  1W1D A;  5J3Y A;  3PEG A;  1WI1 A;  1V5U A;  1TJ6 A;  5C79 A;  2YT0 A;  3QIJ A;  1N3H A;  2CY4 A;  3T06 A;  1PLS A;  4KHO A;  3ULB A;  1MIX A;  1XX0 A;  4A5K A;  1U27 A;  2YS5 A;  1FAO A;  4DX9 0;  1FHW A;  1OY2 A;  4L6E A;  1GG3 A;  1Y5O A;  1GC6 A;  2LOZ A;  2OQB A;  1WGU A;  1H10 A;  5CLL B;  2K2J A;  1KZ7 A;  3KZ1 A;  1M7R A;  1XD4 A;  3ODW A;  1FB8 A;  1DRO A;  3UZT A;  3PVU A;  1UNQ A;  2L2I A;  5HE0 A;  2VSZ A;  3VOQ A;  3HW2 B;  2Y8F A;  4K2O A;  3KRX A;  2KGX B;  2HTH B;  1K5D B;  4HDO A;  2DKQ A;  2CAY A;  2ROV A;  3PVW A;  3HQC A;  5EFX A;  1ZVR A;  4C0A A;  1BWN A;  1XKE A;  3BIN A;  4K2P A;  3BJI A;  2Z0O A;  2J0M A;  3PSC A;  2W2X C;  4A6F B;  1IRS A;  2LOX A;  5J3Q A;  2EC1 A;  4CHJ A;  2M14 A;  1X1G A;  1GC7 A;  3TVV A;  5GOW B;  3PG7 A;  3N7C A;  1SHC A;  2OTX A;  2N0Y A;  3FEH A;  2P0F A;  5C16 A;  2VRW B;  3GYP A;  2DA0 A;  4HHV A;  1Q67 A;  2RGN B;  3DXE A;  4IOY X;  1UNR A;  4K81 A;  4EKU A;  2JP2 A;  5C5B A;  3AU4 A;  1ZC4 B;  2G35 A;  2QKL A;  2RNR B;  5HE2 A;  3AJ4 A;  4GPT B;  3WYF B;  1MKE A;  2M38 A;  1SGH A;  3P6A A;  1KI1 B;  2DHI A;  1RJ2 A;  1XCG A;  2LKO A;  4EMO A;  1H4R A;  2ELA A;  2D10 A;  2MDX A;  3MDB C;  4HAV B;  3PP2 A;  4Z2M B;  4F7H A;  1MIZ B;  2GS0 A;  5JHH A;  1EF1 A;  1LB1 A;  2V76 A;  4CHM A;  4HAU B;  2EMT A;  4YON A;  1X05 A;  1V89 A;  3LJU X;  5L81 A;  1I2H A;  2COF A;  1LW3 A;  2LUL A;  4KAX B;  2DHJ A;  1BAK A;  5KQ4 A;  2J59 M;  1U5F A;  5KCV A;  2YT1 A;  4P7I A;  1BTK A;  2DYN A;  3SNH A;  5HE3 A;  1NU2 A;  1FHO A;  4IFS A;  3DXC A;  3X23 A;  1I7A A;  2VKI A;  5JP4 A;  1U2B A;  1EVH A;  2Z0Q A;  4HAW B;  4H8S A;  3TW1 A;  4TYZ A;  3FM8 C;  1W1H A;  2KUP A;  1P6S A;  1X86 A;  4ZRJ A;  1TQZ A;  4ZRI A;  2DYQ A;  4HB4 B;  3SUZ A;  4Z2N A;  2ELB A;  4F7G A;  1U29 A;  2CRF A;  4HB0 B;  2YVC A;  2ADZ A;  5CLQ B;  2MFQ A;  2ZPY A;  3PZD A;  4GZU A;  1AWE A;  3G9W A;  3IVF A;  2LG1 A;  1MK7 B;  4F7U P;  1K5G B;  2X18 A;  2UZR A;  2P0H A;  4HAT B;  2D9X A;  2DX1 A;  4KHB B;  1EAZ A;  3KY9 A;  2DN6 A;  2Y8G A; 
#chains in the Genus database with same CATH topology
 4HAZ B;  2D11 A;  1DBH A;  1NI2 A;  3MPX A;  4XWX A;  4QJ3 B;  1DDW A;  3DCX A;  2UZS A;  5DIF B;  2ZKM X;  4K17 A;  5DI9 B;  3HK0 A;  3ULC A;  2EJ8 A;  2YS3 A;  1KZG A;  1J19 A;  2COD A;  2YRY A;  1NTY A;  4OSN A;  2NBV A;  3ODO A;  1Y19 B;  3A8Q A;  4HAY B;  2BCJ A;  3ZVR A;  3GYO A;  2DLW A;  1UEF A;  2UVM A;  1W1G A;  3P7Z A;  1UNP A;  2D2Q A;  1U5E A;  1UPQ A;  4ZRK A;  1MAI A;  2I1J A;  5C5B B;  2YS1 A;  1V61 A;  1WJ1 A;  4KHA A;  4QXA B;  5D3X A;  4TKN A;  1RRP B;  5FI0 A;  1V88 A;  1PFJ A;  1P5T A;  4PQ0 A;  1FHX A;  1WJM A;  2GCJ A;  4QJ4 B;  2LYD A;  3V5W A;  5D3Y A;  4MT7 A;  2H7D A;  1XOD A;  2GCL A;  2DFK A;  4GMX B;  2K8E A;  1T77 A;  2XQN M;  1DYN A;  2RLO A;  3SYX A;  2E2X A;  1WVH A;  3A98 B;  2R09 A;  5KQ1 A;  2MKR A;  1E5W A;  2RSG A;  1ZC3 B;  4D0N B;  2R2Y A;  2D4Q A;  4HAX B;  1QC6 A;  4GMV A;  4OT1 A;  2PZ1 A;  5J3T A;  1FGY A;  1P3R A;  2Y7B A;  3TO1 A;  4EJN A;  2L1C A;  4CYE A;  1U5G A;  5FI1 A;  1ISN A;  3O96 A;  3D8F A;  2NZ8 B;  5C6R A;  3M1I B;  5LOP B;  2KCJ A;  2W2W A;  1FGZ A;  3PVL A;  1XR0 B;  1Z87 A;  2DHK A;  3TCA A;  5D3V A;  2QKM A;  2Z0P A;  3SO6 A;  2W2X D;  2YF0 A;  2K00 A;  2KIE A;  3F0W A;  4WJ7 A;  4DX8 A;  2NMB A;  2I5F A;  4DBB A;  3CIK A;  1B55 A;  2AL6 A;  1WGQ A;  4GN1 A;  4IAP A;  3OHM B;  2J0J A;  3F5R A;  4HB3 B;  2H7E A;  5JLJ B;  2YSZ A;  4WVF B;  2K2U A;  3NW8 A;  3FSS A;  1X1F A;  4A6F A;  1UPR A;  3KSY A;  2P0D A;  3ODX A;  1DDM A;  1QQG A;  4NSW A;  2DX5 A;  4A6K A;  1PMS A;  1WG7 A;  3CXB B;  2Z14 A;  1OQN A;  4YL8 A;  4B6H A;  2GJY A;  1EGX A;  3TFM A;  4L1R A;  4MK0 A;  2CY5 A;  3NSU A;  2AEH A;  4NY0 A;  2Z13 A;  2COA A;  5DH9 B;  1BTN A;  3U7D A;  2D9Y A;  2I1K A;  3A58 A;  3QWM A;  1MK9 B;  1V5M A;  4WSF A;  3D8D A;  1U5D A;  2HE7 A;  3SV1 A;  3NWA A;  3QBV B;  1ZSQ A;  3WA0 A;  1FOE A;  2D9V A;  3HIE A;  2EMS A;  3ML4 A;  4GOU A;  5DHF B;  1X11 A;  4MY6 A;  5HE1 A;  3HSA A;  3NWF A;  5I2S A;  4GXB A;  4HDQ A;  2MWN B;  3U8Z A;  5DHA B;  2RVB B;  2IYB A;  2DKP A;  4Y94 A;  3VIA A;  4DXA B;  4BBK A;  1M7E A;  3RCP A;  2D9W A;  2I5C A;  1AQC A;  3ZDT A;  3A8P A;  3AU5 A;  3DXD A;  5I2M A;  5D27 A;  2D9Z A;  1J0W A;  4KVG B;  2P8V A;  4HB2 B;  1OMW A;  2J0K A;  2ROZ B;  2IFS A;  5JHG A;  1V5P A;  1TXD A;  5D3W A;  2Q13 A;  3D8E A;  2DTC A;  2FJU B;  2FJL A;  2KUQ A;  2N23 A;  2RUK B;  4PNK A;  1DDV A;  5LON B;  1ZM0 A;  2COC A;  3KRW A;  3OAN A;  4A6H A;  1MPH A;  1NTV A;  2R0D A;  1W1D A;  5J3Y A;  3PEG A;  1WI1 A;  3B77 A;  2KR0 A;  1V5U A;  1TJ6 A;  5C79 A;  2YT0 A;  3QIJ A;  1N3H A;  1MI1 A;  2CY4 A;  3T06 A;  1PLS A;  4KHO A;  3ULB A;  1MIX A;  1XX0 A;  4A5K A;  4GNK B;  1U27 A;  2YS5 A;  1FAO A;  4DX9 0;  1FHW A;  1OY2 A;  4L6E A;  1GG3 A;  1Y5O A;  1GC6 A;  2LOZ A;  2OQB A;  1WGU A;  1H10 A;  5CLL B;  2K2J A;  1KZ7 A;  3KZ1 A;  1M7R A;  1XD4 A;  3ODW A;  1FB8 A;  1DRO A;  5LG4 B;  3UZT A;  3PVU A;  1UNQ A;  2L2I A;  5HE0 A;  2VSZ A;  3VOQ A;  3HW2 B;  2Y8F A;  4K2O A;  1ZYI A;  2K49 A;  2KGX B;  3KRX A;  2HTH B;  1K5D B;  4HDO A;  2DKQ A;  2CAY A;  2ROV A;  3PVW A;  3HQC A;  5EFX A;  1ZVR A;  4C0A A;  1BWN A;  2Z4D A;  1XKE A;  3BIN A;  4K2P A;  2Z59 A;  3BJI A;  2Z0O A;  2J0M A;  3PSC A;  2W2X C;  4A6F B;  1IRS A;  2LOX A;  5J3Q A;  2EC1 A;  4CHJ A;  2M14 A;  1X1G A;  1GC7 A;  3TVV A;  5GOW B;  3PG7 A;  3N7C A;  1SHC A;  2OTX A;  2N0Y A;  3FEH A;  2P0F A;  5C16 A;  2RRF A;  2VRW B;  3GYP A;  2DA0 A;  4HHV A;  1Q67 A;  2RGN B;  3DXE A;  4IOY X;  1UNR A;  4K81 A;  4EKU A;  2JP2 A;  5C5B A;  3AU4 A;  1ZC4 B;  2G35 A;  2QKL A;  2RNR B;  5HE2 A;  3AJ4 A;  4GPT B;  3WYF B;  1MKE A;  3U12 A;  2M38 A;  1SGH A;  3P6A A;  1KI1 B;  2DHI A;  1RJ2 A;  1XCG A;  2LKO A;  4EMO A;  1H4R A;  2ELA A;  2D10 A;  2MDX A;  3MDB C;  4HAV B;  3PP2 A;  4Z2M B;  4F7H A;  1MIZ B;  2GS0 A;  5JHH A;  1EF1 A;  1LB1 A;  4CSQ A;  2V76 A;  4HSI A;  4CHM A;  2YT2 A;  4HAU B;  2EMT A;  4YON A;  1X05 A;  1V89 A;  3LJU X;  5L81 A;  1I2H A;  2COF A;  1LW3 A;  4QJ5 B;  2LUL A;  4KAX B;  2DHJ A;  3FVC A;  1BAK A;  5KQ4 A;  2GUM A;  2J59 M;  1U5F A;  5KCV A;  2YT1 A;  4P7I A;  1BTK A;  2KIG A;  2DYN A;  3SNH A;  5HE3 A;  1NU2 A;  1FHO A;  4IFS A;  3DXC A;  3X23 A;  1I7A A;  2VKI A;  5JP4 A;  1U2B A;  1EVH A;  2Z0Q A;  4HAW B;  4DIX A;  4H8S A;  3TW1 A;  4TYZ A;  3FM8 C;  5IRS A;  1W1H A;  2KUP A;  1P6S A;  1X86 A;  4ZRJ A;  1TQZ A;  4ZRI A;  2DYQ A;  4HB4 B;  3SUZ A;  4Z2N A;  2ELB A;  4F7G A;  1U29 A;  2CRF A;  4HB0 B;  2YVC A;  2ADZ A;  5CLQ B;  2MFQ A;  2ZPY A;  3PZD A;  4GZU A;  4KHB A;  3NWD A;  1AWE A;  3G9W A;  2LG1 A;  3IVF A;  1MK7 B;  4F7U P;  1K5G B;  4D6W A;  2X18 A;  2UZR A;  2P0H A;  4HAT B;  2D9X A;  2DX1 A;  4KHB B;  1EAZ A;  3KY9 A;  5M4Y B;  2DN6 A;  2Y8G A; 
#chains in the Genus database with same CATH homology
 4HAZ B;  2D11 A;  1DBH A;  1NI2 A;  3MPX A;  4XWX A;  1DDW A;  2UZS A;  5DIF B;  4K17 A;  5DI9 B;  3HK0 A;  3ULC A;  2EJ8 A;  2YS3 A;  1KZG A;  1J19 A;  2COD A;  2YRY A;  1NTY A;  3ODO A;  1Y19 B;  3A8Q A;  4HAY B;  2BCJ A;  3ZVR A;  3GYO A;  2DLW A;  1UEF A;  2UVM A;  1W1G A;  3P7Z A;  1UNP A;  2D2Q A;  1U5E A;  1UPQ A;  4ZRK A;  1MAI A;  2I1J A;  5C5B B;  2YS1 A;  1V61 A;  1WJ1 A;  4KHA A;  5D3X A;  4TKN A;  1RRP B;  5FI0 A;  1V88 A;  1PFJ A;  1P5T A;  4PQ0 A;  1FHX A;  1WJM A;  2GCJ A;  2LYD A;  3V5W A;  5D3Y A;  4MT7 A;  2H7D A;  1XOD A;  2GCL A;  2DFK A;  4GMX B;  2XQN M;  1DYN A;  2RLO A;  3SYX A;  2E2X A;  1WVH A;  3A98 B;  2R09 A;  5KQ1 A;  2MKR A;  1E5W A;  2RSG A;  1ZC3 B;  4D0N B;  2D4Q A;  4HAX B;  1QC6 A;  4GMV A;  2PZ1 A;  5J3T A;  1FGY A;  1P3R A;  2Y7B A;  3TO1 A;  4EJN A;  2L1C A;  4CYE A;  1U5G A;  5FI1 A;  1ISN A;  3O96 A;  3D8F A;  2NZ8 B;  5C6R A;  3M1I B;  5LOP B;  2KCJ A;  2W2W A;  1FGZ A;  3PVL A;  1XR0 B;  1Z87 A;  2DHK A;  3TCA A;  5D3V A;  2QKM A;  2Z0P A;  3SO6 A;  2W2X D;  2YF0 A;  2K00 A;  3F0W A;  4WJ7 A;  4DX8 A;  2NMB A;  2I5F A;  4DBB A;  3CIK A;  1B55 A;  2AL6 A;  1WGQ A;  4GN1 A;  4IAP A;  2J0J A;  3F5R A;  4HB3 B;  2H7E A;  5JLJ B;  2YSZ A;  4WVF B;  2K2U A;  3FSS A;  1X1F A;  4A6F A;  1UPR A;  3KSY A;  2P0D A;  3ODX A;  1DDM A;  1QQG A;  4NSW A;  2DX5 A;  4A6K A;  1PMS A;  1WG7 A;  3CXB B;  1OQN A;  4YL8 A;  4B6H A;  2GJY A;  1EGX A;  3TFM A;  4MK0 A;  2CY5 A;  3NSU A;  2AEH A;  4NY0 A;  2COA A;  5DH9 B;  1BTN A;  3U7D A;  2D9Y A;  2I1K A;  3QWM A;  1MK9 B;  1V5M A;  4WSF A;  3D8D A;  1U5D A;  2HE7 A;  3SV1 A;  3QBV B;  1ZSQ A;  3WA0 A;  1FOE A;  2D9V A;  2EMS A;  3ML4 A;  5DHF B;  1X11 A;  4MY6 A;  5HE1 A;  4GXB A;  4HDQ A;  2MWN B;  3U8Z A;  5DHA B;  2RVB B;  2IYB A;  2DKP A;  4Y94 A;  3VIA A;  4DXA B;  4BBK A;  1M7E A;  3RCP A;  2D9W A;  2I5C A;  1AQC A;  3ZDT A;  3A8P A;  3AU5 A;  3DXD A;  5D27 A;  2D9Z A;  1J0W A;  4KVG B;  2P8V A;  4HB2 B;  1OMW A;  2J0K A;  2ROZ B;  2IFS A;  5JHG A;  1V5P A;  1TXD A;  5D3W A;  2Q13 A;  3D8E A;  2DTC A;  2FJL A;  2N23 A;  2RUK B;  4PNK A;  1DDV A;  5LON B;  1ZM0 A;  2COC A;  3KRW A;  3OAN A;  4A6H A;  1MPH A;  1NTV A;  2R0D A;  1W1D A;  5J3Y A;  3PEG A;  1WI1 A;  1V5U A;  1TJ6 A;  5C79 A;  2YT0 A;  3QIJ A;  1N3H A;  2CY4 A;  3T06 A;  1PLS A;  4KHO A;  3ULB A;  1MIX A;  1XX0 A;  4A5K A;  1U27 A;  2YS5 A;  1FAO A;  4DX9 0;  1FHW A;  1OY2 A;  4L6E A;  1GG3 A;  1Y5O A;  1GC6 A;  2LOZ A;  2OQB A;  1WGU A;  1H10 A;  5CLL B;  2K2J A;  1KZ7 A;  3KZ1 A;  1M7R A;  1XD4 A;  3ODW A;  1FB8 A;  1DRO A;  3UZT A;  3PVU A;  1UNQ A;  2L2I A;  5HE0 A;  2VSZ A;  3VOQ A;  3HW2 B;  2Y8F A;  4K2O A;  3KRX A;  2KGX B;  2HTH B;  1K5D B;  4HDO A;  2DKQ A;  2CAY A;  2ROV A;  3PVW A;  3HQC A;  5EFX A;  1ZVR A;  4C0A A;  1BWN A;  1XKE A;  3BIN A;  4K2P A;  3BJI A;  2Z0O A;  2J0M A;  3PSC A;  2W2X C;  4A6F B;  1IRS A;  2LOX A;  5J3Q A;  2EC1 A;  4CHJ A;  2M14 A;  1X1G A;  1GC7 A;  3TVV A;  5GOW B;  3PG7 A;  3N7C A;  1SHC A;  2OTX A;  2N0Y A;  3FEH A;  2P0F A;  5C16 A;  2VRW B;  3GYP A;  2DA0 A;  4HHV A;  1Q67 A;  2RGN B;  3DXE A;  4IOY X;  1UNR A;  4K81 A;  4EKU A;  2JP2 A;  5C5B A;  3AU4 A;  1ZC4 B;  2G35 A;  2QKL A;  2RNR B;  5HE2 A;  3AJ4 A;  4GPT B;  3WYF B;  1MKE A;  2M38 A;  1SGH A;  3P6A A;  1KI1 B;  2DHI A;  1RJ2 A;  1XCG A;  2LKO A;  4EMO A;  1H4R A;  2ELA A;  2D10 A;  2MDX A;  3MDB C;  4HAV B;  3PP2 A;  4Z2M B;  4F7H A;  1MIZ B;  2GS0 A;  5JHH A;  1EF1 A;  1LB1 A;  2V76 A;  4CHM A;  4HAU B;  2EMT A;  4YON A;  1X05 A;  1V89 A;  3LJU X;  5L81 A;  1I2H A;  2COF A;  1LW3 A;  2LUL A;  4KAX B;  2DHJ A;  1BAK A;  5KQ4 A;  2J59 M;  1U5F A;  5KCV A;  2YT1 A;  4P7I A;  1BTK A;  2DYN A;  3SNH A;  5HE3 A;  1NU2 A;  1FHO A;  4IFS A;  3DXC A;  3X23 A;  1I7A A;  2VKI A;  5JP4 A;  1U2B A;  1EVH A;  2Z0Q A;  4HAW B;  4H8S A;  3TW1 A;  4TYZ A;  3FM8 C;  1W1H A;  2KUP A;  1P6S A;  1X86 A;  4ZRJ A;  1TQZ A;  4ZRI A;  2DYQ A;  4HB4 B;  3SUZ A;  4Z2N A;  2ELB A;  4F7G A;  1U29 A;  2CRF A;  4HB0 B;  2YVC A;  2ADZ A;  5CLQ B;  2MFQ A;  2ZPY A;  3PZD A;  4GZU A;  1AWE A;  3G9W A;  3IVF A;  2LG1 A;  1MK7 B;  4F7U P;  1K5G B;  2X18 A;  2UZR A;  2P0H A;  4HAT B;  2D9X A;  2DX1 A;  4KHB B;  1EAZ A;  3KY9 A;  2DN6 A;  2Y8G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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