4HB3B

Crystal structure of crm1(t539s)-ran-ranbp1 with weakly bound unmodeled leptomycin b
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
121
structure length
121
Chain Sequence
EEDEEVLYKVRAKLFRFDKDAKEWKERGTGDCKFLKNKKTNKVRILMRRDKTLKICANHIIAPEYTLKPNVGSDRSWVYACTADIAEGEAEAFTFAIRFGSKENADKFKEEFEKAQEINKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
pubmed doi rcsb
molecule tags Protein transport/antibiotic
source organism Homo sapiens
molecule keywords GTP-binding nuclear protein Ran
total genus 29
structure length 121
sequence length 121
ec nomenclature
pdb deposition date 2012-09-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00638 Ran_BP1 RanBP1 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 4hb3B00
3QBVB 4K2PA 1UPQA 4ZRKA 1WI1A 2GS0A 3GYPA 2GCJA 4HAUB 4PNKA 3AU5A 2HTHB 4HDOA 1NTVA 1P3RA 1PLSA 1DBHA 2YVCA 2J0JA 4GMVA 4K17A 4HAVB 1WGUA 4HAZB 3KRWA 5C6RA 3TVVA 1B55A 4YONA 5HE3A 5JLJB 4A6HA 3D8FA 2D9XA 5KQ4A 1EF1A 3SO6A 1QQGA 2X18A 3PEGA 3ULBA 1K5GB 2JP2A 1MAIA 2W2XC 1W1GA 4KVGB 4B6HA 4K2OA 5KQ1A 2RGNB 4DX8A 2COCA 2ELBA 3CIKA 1EGXA 2MFQA 2RLOA 4ZRIA 2DX5A 2I5FA 2OQBA 1WVHA 2VRWB 1FOEA 4XWXA 1OQNA 2EMSA 4Z2MB 1P5TA 4GXBA 2YT0A 2L1CA 4KHBB 3FEHA 1ZVRA 2W2XD 1FHXA 2GCLA 4NY0A 4IFSA 2UVMA 1SGHA 1KZ7A 1UEFA 3MDBC 4HATB 3BJIA 5D3YA 4F7UP 1UNPA 2CY4A 2PZ1A 5J3QA 1U5DA 1DDWA 2CRFA 3WYFB 3BINA 2W2WA 1H10A 3DXCA 4HAYB 3TFMA 1WG7A 2LYDA 1FAOA 1XCGA 2DHKA 2D10A 2J0MA 4EMOA 5C5BB 5JP4A 2UZRA 5C79A 5L81A 2EMTA 1X1FA 2YRYA 1FHWA 1WJ1A 2EC1A 2FJLA 2M14A 2RNRB 1P6SA 1V88A 1SHCA 3F5RA 2NMBA 4DBBA 2DX1A 2COFA 2COAA 5LOPB 5HE2A 3X23A 3KY9A 3HQCA 4GN1A 1UNQA 1XR0B 1V89A 2G35A 2RUKB 1AWEA 1XODA 1MK7B 5D3XA 2YT1A 1BTNA 3ZDTA 1BAKA 1U5FA 4A5KA 2J59M 2UZSA 2K00A 1BWNA 1MK9B 1WGQA 2YS1A 3SUZA 3OANA 1ZC4B 2MKRA 2M38A 5HE1A 3M1IB 4A6FA 4GMXB 2DKPA 3A8QA 3HK0A 1J0WA 2DYQA 1U5EA 4L6EA 1DDMA 4KHOA 3PZDA 2HE7A 5FI1A 4MK0A 5FI0A 1DROA 2D9WA 5CLQB 5C5BA 3MPXA 3T06A 1EVHA 2P0DA 3PVWA 2I5CA 3SYXA 1ZC3B 1FGYA 2LOZA 2N0YA 2D2QA 1MKEA 2ADZA 1DYNA 2LG1A 1XX0A 1LB1A 2K2JA 5CLLB 3SNHA 5J3TA 3QWMA 2DHIA 2DN6A 4EKUA 3ODXA 2OTXA 4MY6A 2MDXA 1GC7A 4EJNA 3AU4A 1MIZB 4IOYX 4DXAB 2LULA 2KCJA 5D3VA 2CAYA 2ZPYA 2D11A 2RSGA 2Y8GA 2DKQA 2I1JA 1FB8A 1MIXA 2H7DA 1W1DA 5DI9B 3ULCA 1U2BA 2BCJA 3FM8C 3TO1A 2RVBB 2LKOA 1UPRA 3DXEA 2Z0PA 3A98B 2DYNA 2DHJA 2P0HA 1UNRA 1GC6A 2E2XA 1ZM0A 2I1KA 4H8SA 4WJ7A 1MPHA 4HB0B 3P6AA 2Y7BA 3FSSA 5JHGA 3TW1A 4HHVA 1PMSA 2DLWA 3ML4A 1XKEA 5LONB 3KRXA 2NZ8B 1E5WA 2CODA 4KAXB 3V5WA 4CYEA 4HAWB 1H4RA 3KZ1A 4HB2B 2D9VA 2L2IA 2QKLA 1V5MA 2H7EA 3A8PA 4KHAA 2V76A 1M7RA 1X86A 1J19A 2YS5A 2LOXA 1LW3A 1X1GA 5EFXA 1I2HA 3PP2A 2GJYA 4WSFA 1AQCA 1ZSQA 3ODOA 1U27A 5D3WA 4HB3B 1DDVA 1TJ6A 1TQZA 5JHHA 1Z87A 2R09A 1I7AA 3WA0A 1OMWA 3F0WA 5HE0A 3LJUX 4ZRJA 3D8EA 3HW2B 3SV1A 1WJMA 2QKMA 5D27A 1TXDA 4CHMA 5GOWB 2CY5A 3N7CA 1KI1B 3U8ZA 4IAPA 1FGZA 4Z2NA 1Q67A 4WVFB 3VIAA 5DHAB 1FHOA 1EAZA 1U5GA 2Z0OA 1RRPB 1RJ2A 1M7EA 4D0NB 4DX90 1NI2A 3P7ZA 2R0DA 1ISNA 3AJ4A 3UZTA 2D9ZA 2P8VA 3RCPA 4MT7A 4HB4B 1GG3A 5DHFB 4C0AA 3U7DA 2AL6A 1NU2A 3CXBB 3KSYA 3TCAA 1QC6A 1KZGA 1X05A 3GYOA 1W1HA 4TYZA 2P0FA 1NTYA 3ODWA 1U29A 1V5PA 4K81A 2YSZA 2ROVA 4CHJA 2D4QA 3O96A 1V5UA 4Y94A 4A6KA 4HAXB 4A6FB 4GPTB 1Y19B 2N23A 3PG7A 3ZVRA 5KCVA 4BBKA 2ROZB 3VOQA 2AEHA 3PSCA 4PQ0A 1K5DB 1N3HA 1Y5OA 2VKIA 2YF0A 3DXDA 2VSZA 2EJ8A 2J0KA 2ELAA 5DH9B 4HDQA 2Q13A 2Z0QA 1BTKA 2KUPA 4F7GA 3D8DA 4TKNA 3IVFA 2DTCA 3PVUA 2DA0A 4F7HA 2IYBA 4GZUA 4YL8A 2D9YA 2KGXB 2YS3A 5J3YA 2K2UA 5DIFB 3G9WA 1X11A 1IRSA 5C16A 2MWNB 3PVLA 4NSWA 2Y8FA 1XD4A 2DFKA 2IFSA 3NSUA 1PFJA 1OY2A 2XQNM 4P7IA 3QIJA 1V61A
chains in the Genus database with same CATH superfamily
3QBVB 4K2PA 1UPQA 4ZRKA 1WI1A 2GS0A 3GYPA 2GCJA 4HAUB 4PNKA 3AU5A 3A58A 2HTHB 4HDOA 1NTVA 1P3RA 1PLSA 2KUQA 1DBHA 2YVCA 2J0JA 4GMVA 4K17A 4HAVB 1WGUA 3NWAA 4HAZB 3KRWA 5C6RA 3TVVA 1B55A 4YONA 5HE3A 5JLJB 4A6HA 3D8FA 2D9XA 5KQ4A 1EF1A 3SO6A 1QQGA 2X18A 3PEGA 3ULBA 1K5GB 2JP2A 1MAIA 2W2XC 2K49A 4CSQA 1W1GA 2K8EA 4KVGB 4B6HA 4K2OA 5KQ1A 2RGNB 4DX8A 2COCA 2ELBA 3CIKA 1EGXA 2MFQA 2RLOA 4ZRIA 2DX5A 2I5FA 2OQBA 1WVHA 2VRWB 1FOEA 4XWXA 1OQNA 2EMSA 4Z2MB 1P5TA 2Z4DA 4GXBA 2YT0A 2L1CA 4KHBB 3NWDA 3FEHA 2ZKMX 1ZVRA 2W2XD 1FHXA 2GCLA 4NY0A 4IFSA 2UVMA 1SGHA 1KZ7A 3HSAA 1UEFA 3MDBC 4HATB 3BJIA 5D3YA 5LG4B 4F7UP 1UNPA 2CY4A 2PZ1A 5J3QA 1U5DA 1DDWA 2CRFA 3DCXA 3WYFB 3BINA 2W2WA 4QXAB 1H10A 3DXCA 4HAYB 3TFMA 1WG7A 2LYDA 1FAOA 1XCGA 2DHKA 2D10A 1MI1A 2J0MA 4EMOA 5C5BB 5JP4A 2UZRA 5C79A 5L81A 2EMTA 1X1FA 2YRYA 1FHWA 1WJ1A 2EC1A 2FJLA 2M14A 2RNRB 1P6SA 1V88A 3B77A 1SHCA 3F5RA 2NMBA 4DBBA 2DX1A 2COFA 2COAA 2Z14A 5LOPB 5HE2A 3X23A 3KY9A 3HQCA 4GN1A 1UNQA 1XR0B 1V89A 2G35A 2RUKB 4GNKB 4HSIA 1AWEA 1XODA 1MK7B 5D3XA 2YT1A 1BTNA 3ZDTA 1BAKA 1U5FA 4A5KA 2J59M 2R2YA 2UZSA 2K00A 1BWNA 1MK9B 1WGQA 2YS1A 3SUZA 3OANA 1ZC4B 2MKRA 2M38A 5HE1A 3M1IB 4A6FA 2KIGA 4GMXB 4D6WA 2DKPA 3A8QA 3HK0A 4QJ4B 1J0WA 2DYQA 1U5EA 4L6EA 1DDMA 4KHOA 3PZDA 2HE7A 5FI1A 4MK0A 5FI0A 1DROA 2D9WA 5I2MA 5CLQB 5C5BA 3U12A 3MPXA 3T06A 1EVHA 2P0DA 3PVWA 2I5CA 3SYXA 1ZC3B 1FGYA 2LOZA 2N0YA 2D2QA 1MKEA 2ADZA 1DYNA 2LG1A 1XX0A 1LB1A 2K2JA 5CLLB 3SNHA 5J3TA 3QWMA 2DHIA 2DN6A 4EKUA 3ODXA 2OTXA 4MY6A 2MDXA 1GC7A 4EJNA 3AU4A 1MIZB 4IOYX 4DXAB 2LULA 2KCJA 5D3VA 2CAYA 2ZPYA 2D11A 2RSGA 2Y8GA 2DKQA 2NBVA 2I1JA 1FB8A 1MIXA 2H7DA 4QJ3B 1W1DA 5DI9B 4DIXA 3ULCA 1U2BA 2BCJA 3FM8C 3TO1A 2RVBB 2LKOA 1UPRA 3HIEA 3DXEA 2Z0PA 3A98B 2DYNA 2Z59A 2DHJA 2P0HA 1UNRA 2KIEA 1GC6A 2E2XA 1ZM0A 2I1KA 4H8SA 4WJ7A 1MPHA 4HB0B 3P6AA 2Y7BA 3FSSA 5JHGA 3TW1A 4HHVA 1PMSA 2DLWA 3ML4A 1XKEA 5LONB 3KRXA 2NZ8B 1E5WA 2CODA 4KAXB 3V5WA 4CYEA 4HAWB 1H4RA 3KZ1A 4KHBA 4HB2B 2D9VA 2L2IA 2QKLA 1V5MA 2H7EA 3A8PA 4OSNA 4KHAA 2V76A 1M7RA 1X86A 1J19A 5M4YB 2YS5A 2LOXA 1LW3A 1X1GA 5EFXA 2Z13A 1I2HA 3PP2A 2GJYA 5I2SA 3OHMB 4WSFA 1AQCA 1ZSQA 3ODOA 1U27A 5D3WA 4HB3B 1DDVA 1TJ6A 1TQZA 5JHHA 1Z87A 2R09A 1I7AA 3WA0A 4L1RA 1OMWA 3F0WA 5HE0A 3LJUX 4ZRJA 3D8EA 2KR0A 3HW2B 3SV1A 1WJMA 2QKMA 5D27A 1TXDA 4CHMA 5GOWB 2CY5A 3N7CA 1KI1B 3U8ZA 4IAPA 1FGZA 4Z2NA 1Q67A 2YT2A 4WVFB 3VIAA 5DHAB 1FHOA 1EAZA 1U5GA 2Z0OA 1RRPB 1RJ2A 1M7EA 4D0NB 4DX90 1NI2A 3P7ZA 2GUMA 2R0DA 1ISNA 3AJ4A 5IRSA 3UZTA 3NWFA 2D9ZA 2P8VA 2FJUB 3RCPA 4MT7A 4HB4B 1GG3A 5DHFB 4C0AA 3U7DA 2AL6A 1NU2A 3CXBB 3KSYA 3TCAA 1QC6A 1KZGA 4GOUA 1X05A 3GYOA 1W1HA 4TYZA 4OT1A 2P0FA 1NTYA 3ODWA 1U29A 1V5PA 4K81A 2YSZA 2ROVA 4CHJA 2D4QA 3O96A 1V5UA 4Y94A 4A6KA 4HAXB 4A6FB 4GPTB 1Y19B 2N23A 3PG7A 3ZVRA 5KCVA 4BBKA 2ROZB 2RRFA 3VOQA 2AEHA 3PSCA 4QJ5B 4PQ0A 1K5DB 1N3HA 1Y5OA 2VKIA 2YF0A 3DXDA 2VSZA 2EJ8A 2J0KA 2ELAA 5DH9B 4HDQA 2Q13A 2Z0QA 1BTKA 2KUPA 4F7GA 3D8DA 4TKNA 3IVFA 2DTCA 3FVCA 3PVUA 2DA0A 4F7HA 2IYBA 4GZUA 4YL8A 2D9YA 2KGXB 2YS3A 5J3YA 2K2UA 5DIFB 3G9WA 1X11A 1IRSA 5C16A 2MWNB 3PVLA 3NW8A 4NSWA 2Y8FA 1T77A 1XD4A 2DFKA 2IFSA 3NSUA 1ZYIA 1PFJA 1OY2A 2XQNM 4P7IA 3QIJA 1V61A
chains in the Genus database with same CATH topology
3QBVB 4K2PA 1UPQA 4ZRKA 1WI1A 2GS0A 3GYPA 2GCJA 4HAUB 4PNKA 3AU5A 2HTHB 4HDOA 1NTVA 1P3RA 1PLSA 1DBHA 2YVCA 2J0JA 4GMVA 4K17A 4HAVB 1WGUA 4HAZB 3KRWA 5C6RA 3TVVA 1B55A 4YONA 5HE3A 5JLJB 4A6HA 3D8FA 2D9XA 5KQ4A 1EF1A 3SO6A 1QQGA 2X18A 3PEGA 3ULBA 1K5GB 2JP2A 1MAIA 2W2XC 1W1GA 4KVGB 4B6HA 4K2OA 5KQ1A 2RGNB 4DX8A 2COCA 2ELBA 3CIKA 1EGXA 2MFQA 2RLOA 4ZRIA 2DX5A 2I5FA 2OQBA 1WVHA 2VRWB 1FOEA 4XWXA 1OQNA 2EMSA 4Z2MB 1P5TA 4GXBA 2YT0A 2L1CA 4KHBB 3FEHA 1ZVRA 2W2XD 1FHXA 2GCLA 4NY0A 4IFSA 2UVMA 1SGHA 1KZ7A 1UEFA 3MDBC 4HATB 3BJIA 5D3YA 4F7UP 1UNPA 2CY4A 2PZ1A 5J3QA 1U5DA 1DDWA 2CRFA 3WYFB 3BINA 2W2WA 1H10A 3DXCA 4HAYB 3TFMA 1WG7A 2LYDA 1FAOA 1XCGA 2DHKA 2D10A 2J0MA 4EMOA 5C5BB 5JP4A 2UZRA 5C79A 5L81A 2EMTA 1X1FA 2YRYA 1FHWA 1WJ1A 2EC1A 2FJLA 2M14A 2RNRB 1P6SA 1V88A 1SHCA 3F5RA 2NMBA 4DBBA 2DX1A 2COFA 2COAA 5LOPB 5HE2A 3X23A 3KY9A 3HQCA 4GN1A 1UNQA 1XR0B 1V89A 2G35A 2RUKB 1AWEA 1XODA 1MK7B 5D3XA 2YT1A 1BTNA 3ZDTA 1BAKA 1U5FA 4A5KA 2J59M 2UZSA 2K00A 1BWNA 1MK9B 1WGQA 2YS1A 3SUZA 3OANA 1ZC4B 2MKRA 2M38A 5HE1A 3M1IB 4A6FA 4GMXB 2DKPA 3A8QA 3HK0A 1J0WA 2DYQA 1U5EA 4L6EA 1DDMA 4KHOA 3PZDA 2HE7A 5FI1A 4MK0A 5FI0A 1DROA 2D9WA 5CLQB 5C5BA 3MPXA 3T06A 1EVHA 2P0DA 3PVWA 2I5CA 3SYXA 1ZC3B 1FGYA 2LOZA 2N0YA 2D2QA 1MKEA 2ADZA 1DYNA 2LG1A 1XX0A 1LB1A 2K2JA 5CLLB 3SNHA 5J3TA 3QWMA 2DHIA 2DN6A 4EKUA 3ODXA 2OTXA 4MY6A 2MDXA 1GC7A 4EJNA 3AU4A 1MIZB 4IOYX 4DXAB 2LULA 2KCJA 5D3VA 2CAYA 2ZPYA 2D11A 2RSGA 2Y8GA 2DKQA 2I1JA 1FB8A 1MIXA 2H7DA 1W1DA 5DI9B 3ULCA 1U2BA 2BCJA 3FM8C 3TO1A 2RVBB 2LKOA 1UPRA 3DXEA 2Z0PA 3A98B 2DYNA 2DHJA 2P0HA 1UNRA 1GC6A 2E2XA 1ZM0A 2I1KA 4H8SA 4WJ7A 1MPHA 4HB0B 3P6AA 2Y7BA 3FSSA 5JHGA 3TW1A 4HHVA 1PMSA 2DLWA 3ML4A 1XKEA 5LONB 3KRXA 2NZ8B 1E5WA 2CODA 4KAXB 3V5WA 4CYEA 4HAWB 1H4RA 3KZ1A 4HB2B 2D9VA 2L2IA 2QKLA 1V5MA 2H7EA 3A8PA 4KHAA 2V76A 1M7RA 1X86A 1J19A 2YS5A 2LOXA 1LW3A 1X1GA 5EFXA 1I2HA 3PP2A 2GJYA 4WSFA 1AQCA 1ZSQA 3ODOA 1U27A 5D3WA 4HB3B 1DDVA 1TJ6A 1TQZA 5JHHA 1Z87A 2R09A 1I7AA 3WA0A 1OMWA 3F0WA 5HE0A 3LJUX 4ZRJA 3D8EA 3HW2B 3SV1A 1WJMA 2QKMA 5D27A 1TXDA 4CHMA 5GOWB 2CY5A 3N7CA 1KI1B 3U8ZA 4IAPA 1FGZA 4Z2NA 1Q67A 4WVFB 3VIAA 5DHAB 1FHOA 1EAZA 1U5GA 2Z0OA 1RRPB 1RJ2A 1M7EA 4D0NB 4DX90 1NI2A 3P7ZA 2R0DA 1ISNA 3AJ4A 3UZTA 2D9ZA 2P8VA 3RCPA 4MT7A 4HB4B 1GG3A 5DHFB 4C0AA 3U7DA 2AL6A 1NU2A 3CXBB 3KSYA 3TCAA 1QC6A 1KZGA 1X05A 3GYOA 1W1HA 4TYZA 2P0FA 1NTYA 3ODWA 1U29A 1V5PA 4K81A 2YSZA 2ROVA 4CHJA 2D4QA 3O96A 1V5UA 4Y94A 4A6KA 4HAXB 4A6FB 4GPTB 1Y19B 2N23A 3PG7A 3ZVRA 5KCVA 4BBKA 2ROZB 3VOQA 2AEHA 3PSCA 4PQ0A 1K5DB 1N3HA 1Y5OA 2VKIA 2YF0A 3DXDA 2VSZA 2EJ8A 2J0KA 2ELAA 5DH9B 4HDQA 2Q13A 2Z0QA 1BTKA 2KUPA 4F7GA 3D8DA 4TKNA 3IVFA 2DTCA 3PVUA 2DA0A 4F7HA 2IYBA 4GZUA 4YL8A 2D9YA 2KGXB 2YS3A 5J3YA 2K2UA 5DIFB 3G9WA 1X11A 1IRSA 5C16A 2MWNB 3PVLA 4NSWA 2Y8FA 1XD4A 2DFKA 2IFSA 3NSUA 1PFJA 1OY2A 2XQNM 4P7IA 3QIJA 1V61A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QBV B;  4K2P A;  1UPQ A;  4ZRK A;  1WI1 A;  2GS0 A;  3GYP A;  2GCJ A;  4HAU B;  4PNK A;  3AU5 A;  2HTH B;  4HDO A;  1NTV A;  1P3R A;  1PLS A;  1DBH A;  2YVC A;  2J0J A;  4GMV A;  4K17 A;  4HAV B;  1WGU A;  4HAZ B;  3KRW A;  5C6R A;  3TVV A;  1B55 A;  4YON A;  5HE3 A;  5JLJ B;  4A6H A;  3D8F A;  2D9X A;  5KQ4 A;  1EF1 A;  3SO6 A;  1QQG A;  2X18 A;  3PEG A;  3ULB A;  1K5G B;  2JP2 A;  1MAI A;  2W2X C;  1W1G A;  4KVG B;  4B6H A;  4K2O A;  5KQ1 A;  2RGN B;  4DX8 A;  2COC A;  2ELB A;  3CIK A;  1EGX A;  2MFQ A;  2RLO A;  4ZRI A;  2DX5 A;  2I5F A;  2OQB A;  1WVH A;  2VRW B;  1FOE A;  4XWX A;  1OQN A;  2EMS A;  4Z2M B;  1P5T A;  4GXB A;  2YT0 A;  2L1C A;  4KHB B;  3FEH A;  1ZVR A;  2W2X D;  1FHX A;  2GCL A;  4NY0 A;  4IFS A;  2UVM A;  1SGH A;  1KZ7 A;  1UEF A;  3MDB C;  4HAT B;  3BJI A;  5D3Y A;  4F7U P;  1UNP A;  2CY4 A;  2PZ1 A;  5J3Q A;  1U5D A;  1DDW A;  2CRF A;  3WYF B;  3BIN A;  2W2W A;  1H10 A;  3DXC A;  4HAY B;  3TFM A;  1WG7 A;  2LYD A;  1FAO A;  1XCG A;  2DHK A;  2D10 A;  2J0M A;  4EMO A;  5C5B B;  5JP4 A;  2UZR A;  5C79 A;  5L81 A;  2EMT A;  1X1F A;  2YRY A;  1FHW A;  1WJ1 A;  2EC1 A;  2FJL A;  2M14 A;  2RNR B;  1P6S A;  1V88 A;  1SHC A;  3F5R A;  2NMB A;  4DBB A;  2DX1 A;  2COF A;  2COA A;  5LOP B;  5HE2 A;  3X23 A;  3KY9 A;  3HQC A;  4GN1 A;  1UNQ A;  1XR0 B;  1V89 A;  2G35 A;  2RUK B;  1AWE A;  1XOD A;  1MK7 B;  5D3X A;  2YT1 A;  1BTN A;  3ZDT A;  1BAK A;  1U5F A;  4A5K A;  2J59 M;  2UZS A;  2K00 A;  1BWN A;  1MK9 B;  1WGQ A;  2YS1 A;  3SUZ A;  3OAN A;  1ZC4 B;  2MKR A;  2M38 A;  5HE1 A;  3M1I B;  4A6F A;  4GMX B;  2DKP A;  3A8Q A;  3HK0 A;  1J0W A;  2DYQ A;  1U5E A;  4L6E A;  1DDM A;  4KHO A;  3PZD A;  2HE7 A;  5FI1 A;  4MK0 A;  5FI0 A;  1DRO A;  2D9W A;  5CLQ B;  5C5B A;  3MPX A;  3T06 A;  1EVH A;  2P0D A;  3PVW A;  2I5C A;  3SYX A;  1ZC3 B;  1FGY A;  2LOZ A;  2N0Y A;  2D2Q A;  1MKE A;  2ADZ A;  1DYN A;  2LG1 A;  1XX0 A;  1LB1 A;  2K2J A;  5CLL B;  3SNH A;  5J3T A;  3QWM A;  2DHI A;  2DN6 A;  4EKU A;  3ODX A;  2OTX A;  4MY6 A;  2MDX A;  1GC7 A;  4EJN A;  3AU4 A;  1MIZ B;  4IOY X;  4DXA B;  2LUL A;  2KCJ A;  5D3V A;  2CAY A;  2ZPY A;  2D11 A;  2RSG A;  2Y8G A;  2DKQ A;  2I1J A;  1FB8 A;  1MIX A;  2H7D A;  1W1D A;  5DI9 B;  3ULC A;  1U2B A;  2BCJ A;  3FM8 C;  3TO1 A;  2RVB B;  2LKO A;  1UPR A;  3DXE A;  2Z0P A;  3A98 B;  2DYN A;  2DHJ A;  2P0H A;  1UNR A;  1GC6 A;  2E2X A;  1ZM0 A;  2I1K A;  4H8S A;  4WJ7 A;  1MPH A;  4HB0 B;  3P6A A;  2Y7B A;  3FSS A;  5JHG A;  3TW1 A;  4HHV A;  1PMS A;  2DLW A;  3ML4 A;  1XKE A;  5LON B;  3KRX A;  2NZ8 B;  1E5W A;  2COD A;  4KAX B;  3V5W A;  4CYE A;  4HAW B;  1H4R A;  3KZ1 A;  4HB2 B;  2D9V A;  2L2I A;  2QKL A;  1V5M A;  2H7E A;  3A8P A;  4KHA A;  2V76 A;  1M7R A;  1X86 A;  1J19 A;  2YS5 A;  2LOX A;  1LW3 A;  1X1G A;  5EFX A;  1I2H A;  3PP2 A;  2GJY A;  4WSF A;  1AQC A;  1ZSQ A;  3ODO A;  1U27 A;  5D3W A;  4HB3 B;  1DDV A;  1TJ6 A;  1TQZ A;  5JHH A;  1Z87 A;  2R09 A;  1I7A A;  3WA0 A;  1OMW A;  3F0W A;  5HE0 A;  3LJU X;  4ZRJ A;  3D8E A;  3HW2 B;  3SV1 A;  1WJM A;  2QKM A;  5D27 A;  1TXD A;  4CHM A;  5GOW B;  2CY5 A;  3N7C A;  1KI1 B;  3U8Z A;  4IAP A;  1FGZ A;  4Z2N A;  1Q67 A;  4WVF B;  3VIA A;  5DHA B;  1FHO A;  1EAZ A;  1U5G A;  2Z0O A;  1RRP B;  1RJ2 A;  1M7E A;  4D0N B;  4DX9 0;  1NI2 A;  3P7Z A;  2R0D A;  1ISN A;  3AJ4 A;  3UZT A;  2D9Z A;  2P8V A;  3RCP A;  4MT7 A;  4HB4 B;  1GG3 A;  5DHF B;  4C0A A;  3U7D A;  2AL6 A;  1NU2 A;  3CXB B;  3KSY A;  3TCA A;  1QC6 A;  1KZG A;  1X05 A;  3GYO A;  1W1H A;  4TYZ A;  2P0F A;  1NTY A;  3ODW A;  1U29 A;  1V5P A;  4K81 A;  2YSZ A;  2ROV A;  4CHJ A;  2D4Q A;  3O96 A;  1V5U A;  4Y94 A;  4A6K A;  4HAX B;  4A6F B;  4GPT B;  1Y19 B;  2N23 A;  3PG7 A;  3ZVR A;  5KCV A;  4BBK A;  2ROZ B;  3VOQ A;  2AEH A;  3PSC A;  4PQ0 A;  1K5D B;  1N3H A;  1Y5O A;  2VKI A;  2YF0 A;  3DXD A;  2VSZ A;  2EJ8 A;  2J0K A;  2ELA A;  5DH9 B;  4HDQ A;  2Q13 A;  2Z0Q A;  1BTK A;  2KUP A;  4F7G A;  3D8D A;  4TKN A;  3IVF A;  2DTC A;  3PVU A;  2DA0 A;  4F7H A;  2IYB A;  4GZU A;  4YL8 A;  2D9Y A;  2KGX B;  2YS3 A;  5J3Y A;  2K2U A;  5DIF B;  3G9W A;  1X11 A;  1IRS A;  5C16 A;  2MWN B;  3PVL A;  4NSW A;  2Y8F A;  1XD4 A;  2DFK A;  2IFS A;  3NSU A;  1PFJ A;  1OY2 A;  2XQN M;  4P7I A;  3QIJ A;  1V61 A; 
#chains in the Genus database with same CATH topology
 3QBV B;  4K2P A;  1UPQ A;  4ZRK A;  1WI1 A;  2GS0 A;  3GYP A;  2GCJ A;  4HAU B;  4PNK A;  3AU5 A;  3A58 A;  2HTH B;  4HDO A;  1NTV A;  1P3R A;  1PLS A;  2KUQ A;  1DBH A;  2YVC A;  2J0J A;  4GMV A;  4K17 A;  4HAV B;  1WGU A;  3NWA A;  4HAZ B;  3KRW A;  5C6R A;  3TVV A;  1B55 A;  4YON A;  5HE3 A;  5JLJ B;  4A6H A;  3D8F A;  2D9X A;  5KQ4 A;  1EF1 A;  3SO6 A;  1QQG A;  2X18 A;  3PEG A;  3ULB A;  1K5G B;  2JP2 A;  1MAI A;  2W2X C;  2K49 A;  4CSQ A;  1W1G A;  2K8E A;  4KVG B;  4B6H A;  4K2O A;  5KQ1 A;  2RGN B;  4DX8 A;  2COC A;  2ELB A;  3CIK A;  1EGX A;  2MFQ A;  2RLO A;  4ZRI A;  2DX5 A;  2I5F A;  2OQB A;  1WVH A;  2VRW B;  1FOE A;  4XWX A;  1OQN A;  2EMS A;  4Z2M B;  1P5T A;  2Z4D A;  4GXB A;  2YT0 A;  2L1C A;  4KHB B;  3NWD A;  3FEH A;  2ZKM X;  1ZVR A;  2W2X D;  1FHX A;  2GCL A;  4NY0 A;  4IFS A;  2UVM A;  1SGH A;  1KZ7 A;  3HSA A;  1UEF A;  3MDB C;  4HAT B;  3BJI A;  5D3Y A;  5LG4 B;  4F7U P;  1UNP A;  2CY4 A;  2PZ1 A;  5J3Q A;  1U5D A;  1DDW A;  2CRF A;  3DCX A;  3WYF B;  3BIN A;  2W2W A;  4QXA B;  1H10 A;  3DXC A;  4HAY B;  3TFM A;  1WG7 A;  2LYD A;  1FAO A;  1XCG A;  2DHK A;  2D10 A;  1MI1 A;  2J0M A;  4EMO A;  5C5B B;  5JP4 A;  2UZR A;  5C79 A;  5L81 A;  2EMT A;  1X1F A;  2YRY A;  1FHW A;  1WJ1 A;  2EC1 A;  2FJL A;  2M14 A;  2RNR B;  1P6S A;  1V88 A;  3B77 A;  1SHC A;  3F5R A;  2NMB A;  4DBB A;  2DX1 A;  2COF A;  2COA A;  2Z14 A;  5LOP B;  5HE2 A;  3X23 A;  3KY9 A;  3HQC A;  4GN1 A;  1UNQ A;  1XR0 B;  1V89 A;  2G35 A;  2RUK B;  4GNK B;  4HSI A;  1AWE A;  1XOD A;  1MK7 B;  5D3X A;  2YT1 A;  1BTN A;  3ZDT A;  1BAK A;  1U5F A;  4A5K A;  2J59 M;  2R2Y A;  2UZS A;  2K00 A;  1BWN A;  1MK9 B;  1WGQ A;  2YS1 A;  3SUZ A;  3OAN A;  1ZC4 B;  2MKR A;  2M38 A;  5HE1 A;  3M1I B;  4A6F A;  2KIG A;  4GMX B;  4D6W A;  2DKP A;  3A8Q A;  3HK0 A;  4QJ4 B;  1J0W A;  2DYQ A;  1U5E A;  4L6E A;  1DDM A;  4KHO A;  3PZD A;  2HE7 A;  5FI1 A;  4MK0 A;  5FI0 A;  1DRO A;  2D9W A;  5I2M A;  5CLQ B;  5C5B A;  3U12 A;  3MPX A;  3T06 A;  1EVH A;  2P0D A;  3PVW A;  2I5C A;  3SYX A;  1ZC3 B;  1FGY A;  2LOZ A;  2N0Y A;  2D2Q A;  1MKE A;  2ADZ A;  1DYN A;  2LG1 A;  1XX0 A;  1LB1 A;  2K2J A;  5CLL B;  3SNH A;  5J3T A;  3QWM A;  2DHI A;  2DN6 A;  4EKU A;  3ODX A;  2OTX A;  4MY6 A;  2MDX A;  1GC7 A;  4EJN A;  3AU4 A;  1MIZ B;  4IOY X;  4DXA B;  2LUL A;  2KCJ A;  5D3V A;  2CAY A;  2ZPY A;  2D11 A;  2RSG A;  2Y8G A;  2DKQ A;  2NBV A;  2I1J A;  1FB8 A;  1MIX A;  2H7D A;  4QJ3 B;  1W1D A;  5DI9 B;  4DIX A;  3ULC A;  1U2B A;  2BCJ A;  3FM8 C;  3TO1 A;  2RVB B;  2LKO A;  1UPR A;  3HIE A;  3DXE A;  2Z0P A;  3A98 B;  2DYN A;  2Z59 A;  2DHJ A;  2P0H A;  1UNR A;  2KIE A;  1GC6 A;  2E2X A;  1ZM0 A;  2I1K A;  4H8S A;  4WJ7 A;  1MPH A;  4HB0 B;  3P6A A;  2Y7B A;  3FSS A;  5JHG A;  3TW1 A;  4HHV A;  1PMS A;  2DLW A;  3ML4 A;  1XKE A;  5LON B;  3KRX A;  2NZ8 B;  1E5W A;  2COD A;  4KAX B;  3V5W A;  4CYE A;  4HAW B;  1H4R A;  3KZ1 A;  4KHB A;  4HB2 B;  2D9V A;  2L2I A;  2QKL A;  1V5M A;  2H7E A;  3A8P A;  4OSN A;  4KHA A;  2V76 A;  1M7R A;  1X86 A;  1J19 A;  5M4Y B;  2YS5 A;  2LOX A;  1LW3 A;  1X1G A;  5EFX A;  2Z13 A;  1I2H A;  3PP2 A;  2GJY A;  5I2S A;  3OHM B;  4WSF A;  1AQC A;  1ZSQ A;  3ODO A;  1U27 A;  5D3W A;  4HB3 B;  1DDV A;  1TJ6 A;  1TQZ A;  5JHH A;  1Z87 A;  2R09 A;  1I7A A;  3WA0 A;  4L1R A;  1OMW A;  3F0W A;  5HE0 A;  3LJU X;  4ZRJ A;  3D8E A;  2KR0 A;  3HW2 B;  3SV1 A;  1WJM A;  2QKM A;  5D27 A;  1TXD A;  4CHM A;  5GOW B;  2CY5 A;  3N7C A;  1KI1 B;  3U8Z A;  4IAP A;  1FGZ A;  4Z2N A;  1Q67 A;  2YT2 A;  4WVF B;  3VIA A;  5DHA B;  1FHO A;  1EAZ A;  1U5G A;  2Z0O A;  1RRP B;  1RJ2 A;  1M7E A;  4D0N B;  4DX9 0;  1NI2 A;  3P7Z A;  2GUM A;  2R0D A;  1ISN A;  3AJ4 A;  5IRS A;  3UZT A;  3NWF A;  2D9Z A;  2P8V A;  2FJU B;  3RCP A;  4MT7 A;  4HB4 B;  1GG3 A;  5DHF B;  4C0A A;  3U7D A;  2AL6 A;  1NU2 A;  3CXB B;  3KSY A;  3TCA A;  1QC6 A;  1KZG A;  4GOU A;  1X05 A;  3GYO A;  1W1H A;  4TYZ A;  4OT1 A;  2P0F A;  1NTY A;  3ODW A;  1U29 A;  1V5P A;  4K81 A;  2YSZ A;  2ROV A;  4CHJ A;  2D4Q A;  3O96 A;  1V5U A;  4Y94 A;  4A6K A;  4HAX B;  4A6F B;  4GPT B;  1Y19 B;  2N23 A;  3PG7 A;  3ZVR A;  5KCV A;  4BBK A;  2ROZ B;  2RRF A;  3VOQ A;  2AEH A;  3PSC A;  4QJ5 B;  4PQ0 A;  1K5D B;  1N3H A;  1Y5O A;  2VKI A;  2YF0 A;  3DXD A;  2VSZ A;  2EJ8 A;  2J0K A;  2ELA A;  5DH9 B;  4HDQ A;  2Q13 A;  2Z0Q A;  1BTK A;  2KUP A;  4F7G A;  3D8D A;  4TKN A;  3IVF A;  2DTC A;  3FVC A;  3PVU A;  2DA0 A;  4F7H A;  2IYB A;  4GZU A;  4YL8 A;  2D9Y A;  2KGX B;  2YS3 A;  5J3Y A;  2K2U A;  5DIF B;  3G9W A;  1X11 A;  1IRS A;  5C16 A;  2MWN B;  3PVL A;  3NW8 A;  4NSW A;  2Y8F A;  1T77 A;  1XD4 A;  2DFK A;  2IFS A;  3NSU A;  1ZYI A;  1PFJ A;  1OY2 A;  2XQN M;  4P7I A;  3QIJ A;  1V61 A; 
#chains in the Genus database with same CATH homology
 3QBV B;  4K2P A;  1UPQ A;  4ZRK A;  1WI1 A;  2GS0 A;  3GYP A;  2GCJ A;  4HAU B;  4PNK A;  3AU5 A;  2HTH B;  4HDO A;  1NTV A;  1P3R A;  1PLS A;  1DBH A;  2YVC A;  2J0J A;  4GMV A;  4K17 A;  4HAV B;  1WGU A;  4HAZ B;  3KRW A;  5C6R A;  3TVV A;  1B55 A;  4YON A;  5HE3 A;  5JLJ B;  4A6H A;  3D8F A;  2D9X A;  5KQ4 A;  1EF1 A;  3SO6 A;  1QQG A;  2X18 A;  3PEG A;  3ULB A;  1K5G B;  2JP2 A;  1MAI A;  2W2X C;  1W1G A;  4KVG B;  4B6H A;  4K2O A;  5KQ1 A;  2RGN B;  4DX8 A;  2COC A;  2ELB A;  3CIK A;  1EGX A;  2MFQ A;  2RLO A;  4ZRI A;  2DX5 A;  2I5F A;  2OQB A;  1WVH A;  2VRW B;  1FOE A;  4XWX A;  1OQN A;  2EMS A;  4Z2M B;  1P5T A;  4GXB A;  2YT0 A;  2L1C A;  4KHB B;  3FEH A;  1ZVR A;  2W2X D;  1FHX A;  2GCL A;  4NY0 A;  4IFS A;  2UVM A;  1SGH A;  1KZ7 A;  1UEF A;  3MDB C;  4HAT B;  3BJI A;  5D3Y A;  4F7U P;  1UNP A;  2CY4 A;  2PZ1 A;  5J3Q A;  1U5D A;  1DDW A;  2CRF A;  3WYF B;  3BIN A;  2W2W A;  1H10 A;  3DXC A;  4HAY B;  3TFM A;  1WG7 A;  2LYD A;  1FAO A;  1XCG A;  2DHK A;  2D10 A;  2J0M A;  4EMO A;  5C5B B;  5JP4 A;  2UZR A;  5C79 A;  5L81 A;  2EMT A;  1X1F A;  2YRY A;  1FHW A;  1WJ1 A;  2EC1 A;  2FJL A;  2M14 A;  2RNR B;  1P6S A;  1V88 A;  1SHC A;  3F5R A;  2NMB A;  4DBB A;  2DX1 A;  2COF A;  2COA A;  5LOP B;  5HE2 A;  3X23 A;  3KY9 A;  3HQC A;  4GN1 A;  1UNQ A;  1XR0 B;  1V89 A;  2G35 A;  2RUK B;  1AWE A;  1XOD A;  1MK7 B;  5D3X A;  2YT1 A;  1BTN A;  3ZDT A;  1BAK A;  1U5F A;  4A5K A;  2J59 M;  2UZS A;  2K00 A;  1BWN A;  1MK9 B;  1WGQ A;  2YS1 A;  3SUZ A;  3OAN A;  1ZC4 B;  2MKR A;  2M38 A;  5HE1 A;  3M1I B;  4A6F A;  4GMX B;  2DKP A;  3A8Q A;  3HK0 A;  1J0W A;  2DYQ A;  1U5E A;  4L6E A;  1DDM A;  4KHO A;  3PZD A;  2HE7 A;  5FI1 A;  4MK0 A;  5FI0 A;  1DRO A;  2D9W A;  5CLQ B;  5C5B A;  3MPX A;  3T06 A;  1EVH A;  2P0D A;  3PVW A;  2I5C A;  3SYX A;  1ZC3 B;  1FGY A;  2LOZ A;  2N0Y A;  2D2Q A;  1MKE A;  2ADZ A;  1DYN A;  2LG1 A;  1XX0 A;  1LB1 A;  2K2J A;  5CLL B;  3SNH A;  5J3T A;  3QWM A;  2DHI A;  2DN6 A;  4EKU A;  3ODX A;  2OTX A;  4MY6 A;  2MDX A;  1GC7 A;  4EJN A;  3AU4 A;  1MIZ B;  4IOY X;  4DXA B;  2LUL A;  2KCJ A;  5D3V A;  2CAY A;  2ZPY A;  2D11 A;  2RSG A;  2Y8G A;  2DKQ A;  2I1J A;  1FB8 A;  1MIX A;  2H7D A;  1W1D A;  5DI9 B;  3ULC A;  1U2B A;  2BCJ A;  3FM8 C;  3TO1 A;  2RVB B;  2LKO A;  1UPR A;  3DXE A;  2Z0P A;  3A98 B;  2DYN A;  2DHJ A;  2P0H A;  1UNR A;  1GC6 A;  2E2X A;  1ZM0 A;  2I1K A;  4H8S A;  4WJ7 A;  1MPH A;  4HB0 B;  3P6A A;  2Y7B A;  3FSS A;  5JHG A;  3TW1 A;  4HHV A;  1PMS A;  2DLW A;  3ML4 A;  1XKE A;  5LON B;  3KRX A;  2NZ8 B;  1E5W A;  2COD A;  4KAX B;  3V5W A;  4CYE A;  4HAW B;  1H4R A;  3KZ1 A;  4HB2 B;  2D9V A;  2L2I A;  2QKL A;  1V5M A;  2H7E A;  3A8P A;  4KHA A;  2V76 A;  1M7R A;  1X86 A;  1J19 A;  2YS5 A;  2LOX A;  1LW3 A;  1X1G A;  5EFX A;  1I2H A;  3PP2 A;  2GJY A;  4WSF A;  1AQC A;  1ZSQ A;  3ODO A;  1U27 A;  5D3W A;  4HB3 B;  1DDV A;  1TJ6 A;  1TQZ A;  5JHH A;  1Z87 A;  2R09 A;  1I7A A;  3WA0 A;  1OMW A;  3F0W A;  5HE0 A;  3LJU X;  4ZRJ A;  3D8E A;  3HW2 B;  3SV1 A;  1WJM A;  2QKM A;  5D27 A;  1TXD A;  4CHM A;  5GOW B;  2CY5 A;  3N7C A;  1KI1 B;  3U8Z A;  4IAP A;  1FGZ A;  4Z2N A;  1Q67 A;  4WVF B;  3VIA A;  5DHA B;  1FHO A;  1EAZ A;  1U5G A;  2Z0O A;  1RRP B;  1RJ2 A;  1M7E A;  4D0N B;  4DX9 0;  1NI2 A;  3P7Z A;  2R0D A;  1ISN A;  3AJ4 A;  3UZT A;  2D9Z A;  2P8V A;  3RCP A;  4MT7 A;  4HB4 B;  1GG3 A;  5DHF B;  4C0A A;  3U7D A;  2AL6 A;  1NU2 A;  3CXB B;  3KSY A;  3TCA A;  1QC6 A;  1KZG A;  1X05 A;  3GYO A;  1W1H A;  4TYZ A;  2P0F A;  1NTY A;  3ODW A;  1U29 A;  1V5P A;  4K81 A;  2YSZ A;  2ROV A;  4CHJ A;  2D4Q A;  3O96 A;  1V5U A;  4Y94 A;  4A6K A;  4HAX B;  4A6F B;  4GPT B;  1Y19 B;  2N23 A;  3PG7 A;  3ZVR A;  5KCV A;  4BBK A;  2ROZ B;  3VOQ A;  2AEH A;  3PSC A;  4PQ0 A;  1K5D B;  1N3H A;  1Y5O A;  2VKI A;  2YF0 A;  3DXD A;  2VSZ A;  2EJ8 A;  2J0K A;  2ELA A;  5DH9 B;  4HDQ A;  2Q13 A;  2Z0Q A;  1BTK A;  2KUP A;  4F7G A;  3D8D A;  4TKN A;  3IVF A;  2DTC A;  3PVU A;  2DA0 A;  4F7H A;  2IYB A;  4GZU A;  4YL8 A;  2D9Y A;  2KGX B;  2YS3 A;  5J3Y A;  2K2U A;  5DIF B;  3G9W A;  1X11 A;  1IRS A;  5C16 A;  2MWN B;  3PVL A;  4NSW A;  2Y8F A;  1XD4 A;  2DFK A;  2IFS A;  3NSU A;  1PFJ A;  1OY2 A;  2XQN M;  4P7I A;  3QIJ A;  1V61 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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