4HKNC

Complex structure of human tankyrase 2 with luteolin
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule keywords Tankyrase-2
molecule tags Transferase
source organism Homo sapiens
total genus 1
structure length 47
sequence length 47
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hknC00
4KZLC 5C5RC 4KZUC 4HLKC 4UI6C 5ADSB 5FPFC 4L0TC 4HMHC 4L33C 5ADRB 4L0BC 4L10C 4L2KC 5ADTB 4HLGC 4HLMC 4UVPB 4L2GC 4UI7C 4HKIC 4HKKB 4KZQC 4L0SC 4L31C 4UI5C 5C5PC 4HL5C 4UI3C 5C5QC 4HLFC 4L34C 5ADQB 4HLHC 4L09C 4UI4C 4L2FC 4UI8C 4L0VC 4L0IC 4HKNC 4L32C
chains in the Genus database with same CATH superfamily
4KZLC 3HS2A 5C5RC 4KZUC 4HLKC 4UI6C 3G5OA 3K6QA 5ADSB 5FPFC 4L0TC 4HMHC 4L33C 2ZIXB 2A6QA 3OEIE 3K33B 4L0BC 4L10C 4ZM2A 5ADRB 3HRYA 4L2KC 2ODKA 4HLGC 5ADTB 4HLMC 3CTOA 4L2GC 4UVPB 4UI7C 4ZLXA 4HKIC 4HKKB 3HJ6A 4KZQC 4L0SC 4L31C 4UI5C 5C5PC 3D55A 4HL5C 4UI3C 3OEIA 5C5QC 4ZM0A 4HLFC 4L34C 5ADQB 4HLHC 4L09C 3KH2E 4UI4C 4L2FC 4UI8C 4L0VC 4L0IC 4HKNC 4L32C
chains in the Genus database with same CATH topology
4KZLC 5C5RC 4KZUC 4HLKC 4UI6C 5ADSB 5FPFC 4L0TC 4HMHC 4L33C 2ZIXB 5ADRB 4L0BC 4L10C 4L2KC 5ADTB 4HLGC 4HLMC 4UVPB 4L2GC 4UI7C 4HKIC 4HKKB 3HJ6A 4KZQC 4L0SC 4L31C 4UI5C 5C5PC 4HL5C 4UI3C 5C5QC 4HLFC 4L34C 5ADQB 4HLHC 4L09C 4UI4C 4L2FC 4UI8C 4L0VC 4L0IC 4HKNC 4L32C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KZL C;  5C5R C;  4KZU C;  4HLK C;  4UI6 C;  5ADS B;  5FPF C;  4L0T C;  4HMH C;  4L33 C;  5ADR B;  4L0B C;  4L10 C;  4L2K C;  5ADT B;  4HLG C;  4HLM C;  4UVP B;  4L2G C;  4UI7 C;  4HKI C;  4HKK B;  4KZQ C;  4L0S C;  4L31 C;  4UI5 C;  5C5P C;  4HL5 C;  4UI3 C;  5C5Q C;  4HLF C;  4L34 C;  5ADQ B;  4HLH C;  4L09 C;  4UI4 C;  4L2F C;  4UI8 C;  4L0V C;  4L0I C;  4HKN C;  4L32 C; 
#chains in the Genus database with same CATH topology
 4KZL C;  3HS2 A;  5C5R C;  4KZU C;  4HLK C;  4UI6 C;  3G5O A;  3K6Q A;  5ADS B;  5FPF C;  4L0T C;  4HMH C;  4L33 C;  2ZIX B;  2A6Q A;  3OEI E;  3K33 B;  4L0B C;  4L10 C;  4ZM2 A;  5ADR B;  3HRY A;  4L2K C;  2ODK A;  4HLG C;  5ADT B;  4HLM C;  3CTO A;  4L2G C;  4UVP B;  4UI7 C;  4ZLX A;  4HKI C;  4HKK B;  3HJ6 A;  4KZQ C;  4L0S C;  4L31 C;  4UI5 C;  5C5P C;  3D55 A;  4HL5 C;  4UI3 C;  3OEI A;  5C5Q C;  4ZM0 A;  4HLF C;  4L34 C;  5ADQ B;  4HLH C;  4L09 C;  3KH2 E;  4UI4 C;  4L2F C;  4UI8 C;  4L0V C;  4L0I C;  4HKN C;  4L32 C; 
#chains in the Genus database with same CATH homology
 4KZL C;  5C5R C;  4KZU C;  4HLK C;  4UI6 C;  5ADS B;  5FPF C;  4L0T C;  4HMH C;  4L33 C;  2ZIX B;  5ADR B;  4L0B C;  4L10 C;  4L2K C;  5ADT B;  4HLG C;  4HLM C;  4UVP B;  4L2G C;  4UI7 C;  4HKI C;  4HKK B;  3HJ6 A;  4KZQ C;  4L0S C;  4L31 C;  4UI5 C;  5C5P C;  4HL5 C;  4UI3 C;  5C5Q C;  4HLF C;  4L34 C;  5ADQ B;  4HLH C;  4L09 C;  4UI4 C;  4L2F C;  4UI8 C;  4L0V C;  4L0I C;  4HKN C;  4L32 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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