4HL5C

Complex structure of human tankyrase 2 with 7-hydroxy -4'-methoxyflavone
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule keywords Tankyrase-2
molecule tags Transferase
source organism Homo sapiens
total genus 1
structure length 47
sequence length 47
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hl5C00
5ADTB 4L2FC 4HL5C 4L2GC 4L0SC 4HLFC 4KZUC 5FPFC 4L2KC 5C5RC 4HLKC 4UI4C 4HKNC 4UVPB 4L34C 4HLGC 4L0TC 5C5PC 4L0IC 4KZLC 4L31C 4UI7C 4HLHC 4HLMC 4L0BC 5C5QC 4L32C 4UI5C 4UI6C 4KZQC 4HMHC 4L0VC 5ADQB 4L09C 4HKIC 4L33C 4HKKB 4UI3C 5ADSB 4UI8C 5ADRB 4L10C
chains in the Genus database with same CATH superfamily
5ADTB 4L2FC 4HL5C 3OEIA 3G5OA 2ZIXB 4L2GC 4L0SC 3K6QA 4HLFC 4KZUC 5FPFC 4ZM2A 4ZLXA 4L2KC 5C5RC 3D55A 4HLKC 4UI4C 3KH2E 3K33B 4HKNC 4UVPB 4L34C 3HS2A 4HLGC 2ODKA 4L0TC 5C5PC 4L0IC 4KZLC 4L31C 4UI7C 4HLHC 4HLMC 4L0BC 5C5QC 4L32C 3HJ6A 4UI5C 4UI6C 4KZQC 4HMHC 4L0VC 5ADQB 4L09C 4HKIC 4L33C 4HKKB 3HRYA 4ZM0A 4UI3C 5ADSB 2A6QA 3OEIE 4UI8C 5ADRB 4L10C 3CTOA
chains in the Genus database with same CATH topology
5ADTB 4L2FC 4HL5C 2ZIXB 4L2GC 4L0SC 4HLFC 4KZUC 5FPFC 4L2KC 5C5RC 4HLKC 4UI4C 4HKNC 4UVPB 4L34C 4HLGC 4L0TC 5C5PC 4L0IC 4KZLC 4L31C 4UI7C 4HLHC 4HLMC 4L0BC 5C5QC 4L32C 3HJ6A 4UI5C 4UI6C 4KZQC 4HMHC 4L0VC 5ADQB 4L09C 4HKIC 4L33C 4HKKB 4UI3C 5ADSB 4UI8C 5ADRB 4L10C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5ADT B;  4L2F C;  4HL5 C;  4L2G C;  4L0S C;  4HLF C;  4KZU C;  5FPF C;  4L2K C;  5C5R C;  4HLK C;  4UI4 C;  4HKN C;  4UVP B;  4L34 C;  4HLG C;  4L0T C;  5C5P C;  4L0I C;  4KZL C;  4L31 C;  4UI7 C;  4HLH C;  4HLM C;  4L0B C;  5C5Q C;  4L32 C;  4UI5 C;  4UI6 C;  4KZQ C;  4HMH C;  4L0V C;  5ADQ B;  4L09 C;  4HKI C;  4L33 C;  4HKK B;  4UI3 C;  5ADS B;  4UI8 C;  5ADR B;  4L10 C; 
#chains in the Genus database with same CATH topology
 5ADT B;  4L2F C;  4HL5 C;  3OEI A;  3G5O A;  2ZIX B;  4L2G C;  4L0S C;  3K6Q A;  4HLF C;  4KZU C;  5FPF C;  4ZM2 A;  4ZLX A;  4L2K C;  5C5R C;  3D55 A;  4HLK C;  4UI4 C;  3KH2 E;  3K33 B;  4HKN C;  4UVP B;  4L34 C;  3HS2 A;  4HLG C;  2ODK A;  4L0T C;  5C5P C;  4L0I C;  4KZL C;  4L31 C;  4UI7 C;  4HLH C;  4HLM C;  4L0B C;  5C5Q C;  4L32 C;  3HJ6 A;  4UI5 C;  4UI6 C;  4KZQ C;  4HMH C;  4L0V C;  5ADQ B;  4L09 C;  4HKI C;  4L33 C;  4HKK B;  3HRY A;  4ZM0 A;  4UI3 C;  5ADS B;  2A6Q A;  3OEI E;  4UI8 C;  5ADR B;  4L10 C;  3CTO A; 
#chains in the Genus database with same CATH homology
 5ADT B;  4L2F C;  4HL5 C;  2ZIX B;  4L2G C;  4L0S C;  4HLF C;  4KZU C;  5FPF C;  4L2K C;  5C5R C;  4HLK C;  4UI4 C;  4HKN C;  4UVP B;  4L34 C;  4HLG C;  4L0T C;  5C5P C;  4L0I C;  4KZL C;  4L31 C;  4UI7 C;  4HLH C;  4HLM C;  4L0B C;  5C5Q C;  4L32 C;  3HJ6 A;  4UI5 C;  4UI6 C;  4KZQ C;  4HMH C;  4L0V C;  5ADQ B;  4L09 C;  4HKI C;  4L33 C;  4HKK B;  4UI3 C;  5ADS B;  4UI8 C;  5ADR B;  4L10 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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