4HLHC

Crystal structure of tankyrase 2 in complex with 4'-fluoroflavone
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule keywords Tankyrase-2
molecule tags Transferase
source organism Homo sapiens
total genus 1
structure length 47
sequence length 47
chains with identical sequence D
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hlhC00
5ADQB 4L0IC 4L33C 4KZQC 4UI4C 4L32C 4L10C 4HLMC 4HLFC 4KZLC 4L2FC 4L34C 5C5QC 5ADSB 4L0SC 4HLGC 4UI5C 4UI7C 4L31C 4L09C 4L2GC 4HMHC 4UI6C 4HLHC 4HKKB 4HKIC 5ADTB 4L0BC 4KZUC 5C5PC 5ADRB 4L2KC 4UI8C 5FPFC 4HKNC 5C5RC 4L0VC 4UVPB 4UI3C 4L0TC 4HLKC 4HL5C
chains in the Genus database with same CATH superfamily
4ZM0A 5ADQB 2A6QA 3OEIE 4L0IC 4L33C 4KZQC 3G5OA 4UI4C 4L32C 3HRYA 4L10C 4HLMC 3HS2A 4HLFC 4KZLC 4L2FC 4L34C 5C5QC 5ADSB 4L0SC 3K6QA 4HLGC 2ODKA 4UI5C 4UI7C 3D55A 4L31C 4L09C 4L2GC 4HMHC 4UI6C 4HLHC 4HKIC 4HKKB 5ADTB 3KH2E 4L0BC 4ZLXA 4KZUC 5C5PC 3HJ6A 3OEIA 4L2KC 5ADRB 2ZIXB 4UI8C 5FPFC 4HKNC 5C5RC 3K33B 4L0VC 3CTOA 4UVPB 4ZM2A 4UI3C 4L0TC 4HLKC 4HL5C
chains in the Genus database with same CATH topology
5ADQB 4L0IC 4L33C 4KZQC 4UI4C 4L32C 4L10C 4HLMC 4HLFC 4KZLC 4L2FC 4L34C 5C5QC 5ADSB 4L0SC 4HLGC 4UI5C 4UI7C 4L31C 4L09C 4L2GC 4HMHC 4UI6C 4HLHC 4HKKB 4HKIC 5ADTB 4L0BC 4KZUC 5C5PC 3HJ6A 4L2KC 5ADRB 2ZIXB 4UI8C 5FPFC 4HKNC 5C5RC 4L0VC 4UVPB 4UI3C 4L0TC 4HLKC 4HL5C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5ADQ B;  4L0I C;  4L33 C;  4KZQ C;  4UI4 C;  4L32 C;  4L10 C;  4HLM C;  4HLF C;  4KZL C;  4L2F C;  4L34 C;  5C5Q C;  5ADS B;  4L0S C;  4HLG C;  4UI5 C;  4UI7 C;  4L31 C;  4L09 C;  4L2G C;  4HMH C;  4UI6 C;  4HLH C;  4HKK B;  4HKI C;  5ADT B;  4L0B C;  4KZU C;  5C5P C;  5ADR B;  4L2K C;  4UI8 C;  5FPF C;  4HKN C;  5C5R C;  4L0V C;  4UVP B;  4UI3 C;  4L0T C;  4HLK C;  4HL5 C; 
#chains in the Genus database with same CATH topology
 4ZM0 A;  5ADQ B;  2A6Q A;  3OEI E;  4L0I C;  4L33 C;  4KZQ C;  3G5O A;  4UI4 C;  4L32 C;  3HRY A;  4L10 C;  4HLM C;  3HS2 A;  4HLF C;  4KZL C;  4L2F C;  4L34 C;  5C5Q C;  5ADS B;  4L0S C;  3K6Q A;  4HLG C;  2ODK A;  4UI5 C;  4UI7 C;  3D55 A;  4L31 C;  4L09 C;  4L2G C;  4HMH C;  4UI6 C;  4HLH C;  4HKI C;  4HKK B;  5ADT B;  3KH2 E;  4L0B C;  4ZLX A;  4KZU C;  5C5P C;  3HJ6 A;  3OEI A;  4L2K C;  5ADR B;  2ZIX B;  4UI8 C;  5FPF C;  4HKN C;  5C5R C;  3K33 B;  4L0V C;  3CTO A;  4UVP B;  4ZM2 A;  4UI3 C;  4L0T C;  4HLK C;  4HL5 C; 
#chains in the Genus database with same CATH homology
 5ADQ B;  4L0I C;  4L33 C;  4KZQ C;  4UI4 C;  4L32 C;  4L10 C;  4HLM C;  4HLF C;  4KZL C;  4L2F C;  4L34 C;  5C5Q C;  5ADS B;  4L0S C;  4HLG C;  4UI5 C;  4UI7 C;  4L31 C;  4L09 C;  4L2G C;  4HMH C;  4UI6 C;  4HLH C;  4HKK B;  4HKI C;  5ADT B;  4L0B C;  4KZU C;  5C5P C;  3HJ6 A;  4L2K C;  5ADR B;  2ZIX B;  4UI8 C;  5FPF C;  4HKN C;  5C5R C;  4L0V C;  4UVP B;  4UI3 C;  4L0T C;  4HLK C;  4HL5 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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