4IOAD

Crystal structure of compound 4e bound to large ribosomal subunit (50s) from deinococcus radiodurans
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
177
structure length
177
Chain Sequence
QLKTKYNDQVRPALMQQFGYSSVMAVPRIEKIVVNEGLGSSKEDSKAIDKAAKELALITLQKPIITKAKKSISNFKLRQGMPVGIKVTLRGERMYVFLEKLINIGLPRIRDFRGINPNAFDGRGNYNLGIKEQLIFPEITYDMVDKTRGMDITIVTTAKTDEEARALLQSMGLPFRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
pubmed doi rcsb
molecule tags Ribosome/ribosome inhibitor
molecule keywords 23S ribosomal RNA
total genus 24
structure length 177
sequence length 177
ec nomenclature
pdb deposition date 2013-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 4ioaD00
4IO9D 1Q86F 1M1KF 1VQMD 3G6ED 1VQ6D 3CMAD 2ZJQD 2NWUA 3CCVD 3CCLD 1Q81F 1YJND 3I56D 4UY8F 3CC2D 1Q7YF 1N8RF 5JVGD 1NJIF 3CC4D 1K9MF 3CMED 3PIOD 2QEXD 1YIJD 1VQLD 1VQPD 3CXCD 2ZJPD 3CCUD 2ZJRD 1S72D 3OW2D 1VQOD 4WFBD 3CC7D 3CCSD 3CF5D 5DM7D 1KQSD 3CD6D 1QVFD 2OGKA 5H1SH 3CPWD 3CCED 1MJIA 4IOCD 1YI2D 1Q82F 1K8AF 4WCED 3I55D 4U67D 4WFND 4WFAD 1VQ5D 3J7ZF 2OTLD 1W2BD 4WF9D 1VQ7D 3D7AA 3CCRD 4IOAD 3CCJD 1IQ4A 1VQ4D 3DLLD 5JVHD 3CCMD 3G71D 1YHQD 5GADF 2NRQA 1KD1F 5DM6D 2WNYA 2OTJD 5GAGF 1VQ8D 3PIPD 1YJ9D 1VQKD 3G4SD 3CCQD 2QA4D 1JJ2D 1YJWD 5GAEF 1QVGD 5HL7D 1VQND 1M90F 5MLCG 1K73F 3C9GA 2PZZA 1KC8F 1VQ9D 1YITD 5GAHF
chains in the Genus database with same CATH superfamily
4IO9D 1Q86F 1M1KF 1VQMD 3G6ED 1VQ6D 3CMAD 2ZJQD 2NWUA 3CCVD 3CCLD 1Q81F 1YJND 3I56D 4UY8F 3CC2D 1Q7YF 1N8RF 5JVGD 1NJIF 3CC4D 1K9MF 3CMED 3PIOD 2QEXD 1YIJD 1VQLD 1VQPD 3CXCD 2ZJPD 3CCUD 2ZJRD 1S72D 3OW2D 1VQOD 4WFBD 3CC7D 3CCSD 3CF5D 5DM7D 1KQSD 3CD6D 1QVFD 2OGKA 5H1SH 3CPWD 3CCED 1MJIA 4IOCD 1YI2D 1Q82F 1K8AF 4WCED 3I55D 4U67D 4WFND 4WFAD 1VQ5D 3J7ZF 2OTLD 1W2BD 4WF9D 1VQ7D 3D7AA 3CCRD 4IOAD 3CCJD 1IQ4A 1VQ4D 3DLLD 5JVHD 3CCMD 3G71D 1YHQD 5GADF 2NRQA 1KD1F 5DM6D 2WNYA 2OTJD 5GAGF 1VQ8D 3PIPD 1YJ9D 1VQKD 3G4SD 3CCQD 2QA4D 1JJ2D 1YJWD 5GAEF 1QVGD 5HL7D 1VQND 1M90F 5MLCG 1K73F 3C9GA 2PZZA 1KC8F 1VQ9D 1YITD 5GAHF
chains in the Genus database with same CATH topology
4IO9D 1Q86F 1M1KF 1VQMD 3G6ED 1VQ6D 3CMAD 2ZJQD 2NWUA 3CCVD 3CCLD 1Q81F 1YJND 3I56D 4UY8F 3CC2D 1Q7YF 1N8RF 5JVGD 1NJIF 3CC4D 1K9MF 3CMED 3PIOD 2QEXD 1YIJD 1VQLD 1VQPD 3CXCD 2ZJPD 3CCUD 2ZJRD 1S72D 3OW2D 1VQOD 4WFBD 3CC7D 3CCSD 3CF5D 5DM7D 1KQSD 3CD6D 1QVFD 2OGKA 5H1SH 3CPWD 3CCED 1MJIA 4IOCD 1YI2D 1Q82F 1K8AF 4WCED 3I55D 4U67D 4WFND 4WFAD 1VQ5D 3J7ZF 2OTLD 1W2BD 4WF9D 1VQ7D 3D7AA 3CCRD 4IOAD 3CCJD 1IQ4A 1VQ4D 3DLLD 5JVHD 3CCMD 3G71D 1YHQD 5GADF 2NRQA 1KD1F 5DM6D 2WNYA 2OTJD 5GAGF 1VQ8D 3PIPD 1YJ9D 1VQKD 3G4SD 3CCQD 2QA4D 1JJ2D 1YJWD 5GAEF 1QVGD 5HL7D 1VQND 1M90F 5MLCG 1K73F 3C9GA 2PZZA 1KC8F 1VQ9D 1YITD 5GAHF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IO9 D;  1Q86 F;  1M1K F;  1VQM D;  3G6E D;  1VQ6 D;  3CMA D;  2ZJQ D;  2NWU A;  3CCV D;  3CCL D;  1Q81 F;  1YJN D;  3I56 D;  4UY8 F;  3CC2 D;  1Q7Y F;  1N8R F;  5JVG D;  1NJI F;  3CC4 D;  1K9M F;  3CME D;  3PIO D;  2QEX D;  1YIJ D;  1VQL D;  1VQP D;  3CXC D;  2ZJP D;  3CCU D;  2ZJR D;  1S72 D;  3OW2 D;  1VQO D;  4WFB D;  3CC7 D;  3CCS D;  3CF5 D;  5DM7 D;  1KQS D;  3CD6 D;  1QVF D;  2OGK A;  5H1S H;  3CPW D;  3CCE D;  1MJI A;  4IOC D;  1YI2 D;  1Q82 F;  1K8A F;  4WCE D;  3I55 D;  4U67 D;  4WFN D;  4WFA D;  1VQ5 D;  3J7Z F;  2OTL D;  1W2B D;  4WF9 D;  1VQ7 D;  3D7A A;  3CCR D;  4IOA D;  3CCJ D;  1IQ4 A;  1VQ4 D;  3DLL D;  5JVH D;  3CCM D;  3G71 D;  1YHQ D;  5GAD F;  2NRQ A;  1KD1 F;  5DM6 D;  2WNY A;  2OTJ D;  5GAG F;  1VQ8 D;  3PIP D;  1YJ9 D;  1VQK D;  3G4S D;  3CCQ D;  2QA4 D;  1JJ2 D;  1YJW D;  5GAE F;  1QVG D;  5HL7 D;  1VQN D;  1M90 F;  5MLC G;  1K73 F;  3C9G A;  2PZZ A;  1KC8 F;  1VQ9 D;  1YIT D;  5GAH F; 
#chains in the Genus database with same CATH topology
 4IO9 D;  1Q86 F;  1M1K F;  1VQM D;  3G6E D;  1VQ6 D;  3CMA D;  2ZJQ D;  2NWU A;  3CCV D;  3CCL D;  1Q81 F;  1YJN D;  3I56 D;  4UY8 F;  3CC2 D;  1Q7Y F;  1N8R F;  5JVG D;  1NJI F;  3CC4 D;  1K9M F;  3CME D;  3PIO D;  2QEX D;  1YIJ D;  1VQL D;  1VQP D;  3CXC D;  2ZJP D;  3CCU D;  2ZJR D;  1S72 D;  3OW2 D;  1VQO D;  4WFB D;  3CC7 D;  3CCS D;  3CF5 D;  5DM7 D;  1KQS D;  3CD6 D;  1QVF D;  2OGK A;  5H1S H;  3CPW D;  3CCE D;  1MJI A;  4IOC D;  1YI2 D;  1Q82 F;  1K8A F;  4WCE D;  3I55 D;  4U67 D;  4WFN D;  4WFA D;  1VQ5 D;  3J7Z F;  2OTL D;  1W2B D;  4WF9 D;  1VQ7 D;  3D7A A;  3CCR D;  4IOA D;  3CCJ D;  1IQ4 A;  1VQ4 D;  3DLL D;  5JVH D;  3CCM D;  3G71 D;  1YHQ D;  5GAD F;  2NRQ A;  1KD1 F;  5DM6 D;  2WNY A;  2OTJ D;  5GAG F;  1VQ8 D;  3PIP D;  1YJ9 D;  1VQK D;  3G4S D;  3CCQ D;  2QA4 D;  1JJ2 D;  1YJW D;  5GAE F;  1QVG D;  5HL7 D;  1VQN D;  1M90 F;  5MLC G;  1K73 F;  3C9G A;  2PZZ A;  1KC8 F;  1VQ9 D;  1YIT D;  5GAH F; 
#chains in the Genus database with same CATH homology
 4IO9 D;  1Q86 F;  1M1K F;  1VQM D;  3G6E D;  1VQ6 D;  3CMA D;  2ZJQ D;  2NWU A;  3CCV D;  3CCL D;  1Q81 F;  1YJN D;  3I56 D;  4UY8 F;  3CC2 D;  1Q7Y F;  1N8R F;  5JVG D;  1NJI F;  3CC4 D;  1K9M F;  3CME D;  3PIO D;  2QEX D;  1YIJ D;  1VQL D;  1VQP D;  3CXC D;  2ZJP D;  3CCU D;  2ZJR D;  1S72 D;  3OW2 D;  1VQO D;  4WFB D;  3CC7 D;  3CCS D;  3CF5 D;  5DM7 D;  1KQS D;  3CD6 D;  1QVF D;  2OGK A;  5H1S H;  3CPW D;  3CCE D;  1MJI A;  4IOC D;  1YI2 D;  1Q82 F;  1K8A F;  4WCE D;  3I55 D;  4U67 D;  4WFN D;  4WFA D;  1VQ5 D;  3J7Z F;  2OTL D;  1W2B D;  4WF9 D;  1VQ7 D;  3D7A A;  3CCR D;  4IOA D;  3CCJ D;  1IQ4 A;  1VQ4 D;  3DLL D;  5JVH D;  3CCM D;  3G71 D;  1YHQ D;  5GAD F;  2NRQ A;  1KD1 F;  5DM6 D;  2WNY A;  2OTJ D;  5GAG F;  1VQ8 D;  3PIP D;  1YJ9 D;  1VQK D;  3G4S D;  3CCQ D;  2QA4 D;  1JJ2 D;  1YJW D;  5GAE F;  1QVG D;  5HL7 D;  1VQN D;  1M90 F;  5MLC G;  1K73 F;  3C9G A;  2PZZ A;  1KC8 F;  1VQ9 D;  1YIT D;  5GAH F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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