4K2PA

The structure of a quintuple mutant of the tiam1 ph-cc-ex domain
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
238
structure length
238
Chain Sequence
TVRKAGALAVKNFLVHKKNKKVESATRRKWKHYWVSLKGCTLFFYESDGRSGIDHNSIPKHAVWVENSIVQAVPEHPKKDFVFCLSNSLGDAFLFQTTSQTELENWITAIHSACATAVARHHHKEDTLRLLKSEIKKLEQKIDMDEKLKKMGELQLSSVTDSKAAATILDQIFVWEQNLEQFQMDLFRFRCYLASLQGGELPNPKRLLAFASRPTKVAMGRLGIFSVSSFHALVAART
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title High-resolution structure of the Tiam1 PHn-CC-Ex domain.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords T-lymphoma invasion and metastasis-inducing protein 1
total genus 78
structure length 238
sequence length 238
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-04-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
A PF18385 Tiam_CC_Ex T-lymphoma invasion and metastasis CC-Ex domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 4k2pA01
5J3QA 2VSZA 2E2XA 4KVGB 2ZPYA 3FEHA 2YSZA 1E5WA 3FM8C 3PEGA 2IYBA 4HATB 1RJ2A 2LULA 3T06A 1V61A 1NTVA 2GCJA 2P0HA 3NSUA 2I5CA 1WGUA 1X05A 1PFJA 3CIKA 2YVCA 3OANA 5C5BB 2VRWB 2DN6A 4KHAA 2W2XD 4Z2MB 1FGYA 1ZC3B 1ZM0A 2DHIA 2YT1A 1U29A 2JP2A 1NU2A 1M7EA 5C5BA 1FHXA 1U2BA 1Y19B 3V5WA 2R0DA 2DFKA 1RRPB 2MDXA 4GPTB 4GXBA 5D3WA 3ODOA 1J0WA 5D27A 2J0KA 2RNRB 5HE3A 2L1CA 4DXAB 1ZC4B 2AEHA 3P6AA 3ML4A 3PSCA 1TJ6A 3ZVRA 5C79A 3MDBC 3GYPA 3HW2B 5JHGA 1XODA 2P0DA 4K81A 2KCJA 2D9XA 3M1IB 2DA0A 2W2XC 4ZRIA 1UPQA 1V89A 2Z0QA 2W2WA 1X1FA 3DXCA 5DI9B 5JP4A 1ZVRA 2ELBA 3TVVA 1P6SA 4DX90 4H8SA 2AL6A 2D9YA 5L81A 1MIXA 1DDMA 4HDOA 1P5TA 3VIAA 4Y94A 5J3TA 3SO6A 3ULCA 4TYZA 5DH9B 4D0NB 5EFXA 3X23A 2DTCA 1Q67A 4YL8A 3U7DA 3QIJA 2I1JA 3HK0A 1U5GA 2Q13A 1FGZA 3TFMA 3KSYA 3D8DA 5JLJB 4ZRKA 2QKLA 2FJLA 3QWMA 3ODWA 4KAXB 1WI1A 2D9ZA 3SNHA 2N0YA 1OMWA 2G35A 2L2IA 2ROVA 3G9WA 2CAYA 2GJYA 3MPXA 2LOZA 2Y8FA 3TCAA 4KHOA 3D8EA 2H7EA 5LONB 5FI1A 2DHJA 4P7IA 4EKUA 4IFSA 4WSFA 2M38A 1UNRA 2LOXA 1U5DA 1V5PA 5C16A 1DBHA 2LYDA 1J19A 3N7CA 2LG1A 3SYXA 1NTYA 1DROA 2HTHB 5LOPB 5GOWB 2GCLA 2CY5A 4L6EA 4CYEA 1BTKA 4HB2B 1W1DA 2I5FA 4C0AA 4HAXB 3A8PA 1OY2A 4EMOA 1EVHA 3TO1A 1FB8A 2Y7BA 4IAPA 1H4RA 3AU4A 2N23A 2D9VA 3U8ZA 2DHKA 1XCGA 1N3HA 2CY4A 1FAOA 2RLOA 3HQCA 2ELAA 5KCVA 2MWNB 4MK0A 1V5MA 4BBKA 4DBBA 1KZ7A 1UNPA 1WGQA 1EF1A 1XR0B 3DXEA 1U5EA 1LW3A 2J0MA 1BTNA 4PNKA 2KUPA 5D3YA 3QBVB 4ZRJA 1WVHA 4HB3B 1X86A 1EAZA 3TW1A 3P7ZA 2DKQA 2DLWA 3CXBB 4NY0A 2OTXA 3GYOA 4HAVB 2ADZA 4CHMA 3ODXA 5DIFB 2J59M 3KRXA 4GMVA 1QQGA 3PVWA 2H7DA 5FI0A 4NSWA 4K2PA 4HB4B 4HAUB 2PZ1A 4HB0B 2IFSA 2D9WA 4GZUA 3RCPA 3A8QA 1WG7A 3WYFB 4HAYB 1Y5OA 2K00A 1I2HA 4B6HA 5C6RA 1PMSA 2COFA 2DX5A 5HE2A 1TQZA 4GMXB 1I7AA 4HHVA 3PVUA 2EMSA 2OQBA 3F0WA 1XX0A 2ROZB 2P8VA 4A6HA 2MFQA 2RVBB 1B55A 1WJMA 2HE7A 4YONA 2COCA 2MKRA 5DHFB 5J3YA 2D10A 2YRYA 2YS5A 2I1KA 3SUZA 1XD4A 1FHOA 1MPHA 1V5UA 1SHCA 3VOQA 4F7UP 1K5DB 1EGXA 1MAIA 2NZ8B 5CLQB 1Z87A 1GC6A 1W1HA 2YS1A 3A98B 1X1GA 2X18A 1MK7B 4TKNA 2VKIA 1DYNA 4HDQA 4K2OA 3AJ4A 4KHBB 1PLSA 5D3VA 2YT0A 4IOYX 2KGXB 1U5FA 1OQNA 3KY9A 4DX8A 4CHJA 2EJ8A 1FHWA 1X11A 4WJ7A 2LKOA 1WJ1A 2D2QA 2DX1A 5HE1A 1U27A 1SGHA 4WVFB 3AU5A 2DYQA 2K2JA 1BWNA 1DDWA 2P0FA 3D8FA 1FOEA 2D11A 2J0JA 2UZSA 2RUKB 4K17A 1GC7A 2Z0OA 4HAWB 4F7GA 1QC6A 3PVLA 3F5RA 5KQ1A 1UNQA 5DHAB 1V88A 3DXDA 5D3XA 2R09A 1MKEA 2QKMA 2BCJA 2COAA 3PP2A 2UVMA 3SV1A 3WA0A 1H10A 4MT7A 3KRWA 2Z0PA 3IVFA 1MK9B 4A6KA 4A5KA 1MIZB 3KZ1A 1K5GB 1XKEA 2EMTA 4Z2NA 2YF0A 2D4QA 2V76A 2Y8GA 1AQCA 1P3RA 5JHHA 1NI2A 5HE0A 1BAKA 2EC1A 3ULBA 3LJUX 2K2UA 4GN1A 1LB1A 4XWXA 4F7HA 5CLLB 3ZDTA 1KZGA 3PZDA 2RSGA 3PG7A 2YS3A 1AWEA 1GG3A 2XQNM 1KI1B 1DDVA 1UPRA 3FSSA 4HAZB 2NMBA 3BINA 3UZTA 1IRSA 2DYNA 4A6FB 2CRFA 1UEFA 1M7RA 4MY6A 2GS0A 5KQ4A 3BJIA 1TXDA 2CODA 2DKPA 3O96A 4A6FA 1W1GA 1ZSQA 2UZRA 2M14A 2RGNB 4EJNA 4PQ0A 1ISNA
chains in the Genus database with same CATH superfamily
5J3QA 2VSZA 2E2XA 4KVGB 2ZPYA 3FEHA 2YSZA 1E5WA 4DIXA 3FM8C 3PEGA 2IYBA 4HATB 1RJ2A 2LULA 2K49A 3T06A 1V61A 1NTVA 2GCJA 2P0HA 3NSUA 2I5CA 2Z13A 1WGUA 1X05A 1PFJA 3CIKA 2YVCA 1ZYIA 5I2MA 3OANA 5C5BB 2VRWB 2DN6A 4KHAA 2W2XD 4Z2MB 1FGYA 1ZC3B 1ZM0A 2DHIA 2YT1A 1U29A 2JP2A 1NU2A 1M7EA 5C5BA 1FHXA 1U2BA 1Y19B 3V5WA 2R0DA 2DFKA 1RRPB 2MDXA 4GPTB 4GXBA 5D3WA 2FJUB 3ODOA 1J0WA 5D27A 2J0KA 3FVCA 2RNRB 4OT1A 5HE3A 2L1CA 4DXAB 1ZC4B 2AEHA 5LG4B 3P6AA 5IRSA 3ML4A 3PSCA 1TJ6A 4OSNA 4HSIA 3ZVRA 5C79A 3MDBC 3GYPA 3HW2B 5JHGA 1XODA 2P0DA 4K81A 2KCJA 2D9XA 3M1IB 2DA0A 2W2XC 4ZRIA 1UPQA 1V89A 2Z0QA 2W2WA 1X1FA 3DXCA 5DI9B 5JP4A 1ZVRA 2ELBA 3TVVA 1P6SA 4DX90 2Z14A 4H8SA 2AL6A 2D9YA 5L81A 1MIXA 1DDMA 3NW8A 4HDOA 1P5TA 3VIAA 4Y94A 5J3TA 3HIEA 3SO6A 3ULCA 4TYZA 5DH9B 4D0NB 5EFXA 3X23A 2DTCA 1Q67A 4YL8A 4QJ3B 3U7DA 3QIJA 2I1JA 3HK0A 3NWAA 1U5GA 2Q13A 1FGZA 3TFMA 3KSYA 3D8DA 2KUQA 3NWFA 5JLJB 2YT2A 2QKLA 4ZRKA 2FJLA 4GOUA 3QWMA 3ODWA 4KAXB 1WI1A 2D9ZA 2R2YA 3SNHA 2N0YA 1OMWA 4L1RA 2G35A 2L2IA 2ROVA 3G9WA 2CAYA 2GJYA 3MPXA 2LOZA 2Y8FA 3TCAA 4KHOA 3D8EA 2H7EA 5LONB 5FI1A 2DHJA 2ZKMX 4P7IA 4EKUA 4IFSA 4WSFA 2M38A 1UNRA 2LOXA 1U5DA 1V5PA 5C16A 1DBHA 2LYDA 1J19A 3N7CA 2LG1A 3SYXA 1NTYA 1DROA 2HTHB 5LOPB 5GOWB 3U12A 2GCLA 2CY5A 4L6EA 2K8EA 4CYEA 1BTKA 4HB2B 1W1DA 2I5FA 1T77A 4C0AA 4HAXB 3A8PA 1OY2A 4EMOA 1EVHA 3TO1A 1FB8A 2Y7BA 4IAPA 1H4RA 3AU4A 2N23A 2D9VA 3U8ZA 2DHKA 1XCGA 1N3HA 2CY4A 1FAOA 2RLOA 3HQCA 2ELAA 5KCVA 2MWNB 4MK0A 1V5MA 4BBKA 4DBBA 1KZ7A 1UNPA 1WGQA 2KR0A 1EF1A 1XR0B 3DXEA 1U5EA 1LW3A 2J0MA 1BTNA 4PNKA 2KUPA 5D3YA 3QBVB 4ZRJA 1WVHA 4HB3B 1X86A 1EAZA 3TW1A 3P7ZA 2DKQA 2DLWA 3CXBB 4NY0A 2OTXA 3GYOA 4HAVB 3A58A 2ADZA 4CHMA 3B77A 3ODXA 5DIFB 2J59M 3OHMB 3KRXA 3HSAA 4GMVA 1QQGA 3PVWA 2H7DA 5FI0A 4CSQA 4NSWA 4K2PA 4HB4B 3NWDA 4HAUB 2PZ1A 4HB0B 2IFSA 4QJ4B 2D9WA 4GZUA 3RCPA 3A8QA 1WG7A 3WYFB 4HAYB 1Y5OA 2K00A 1MI1A 1I2HA 4B6HA 5C6RA 1PMSA 2COFA 2DX5A 5HE2A 1TQZA 4GMXB 1I7AA 4HHVA 3PVUA 2EMSA 2OQBA 3F0WA 1XX0A 2ROZB 2P8VA 4A6HA 2MFQA 2RVBB 4GNKB 1B55A 1WJMA 2HE7A 4YONA 2COCA 2MKRA 5DHFB 2NBVA 5J3YA 2D10A 2YRYA 2YS5A 2I1KA 3SUZA 1XD4A 1FHOA 1MPHA 1V5UA 1SHCA 3VOQA 4F7UP 1K5DB 1EGXA 1MAIA 2NZ8B 5CLQB 1Z87A 1GC6A 1W1HA 2YS1A 3A98B 1X1GA 2X18A 1MK7B 4TKNA 2VKIA 1DYNA 4HDQA 4K2OA 2Z59A 3AJ4A 4KHBB 1PLSA 5D3VA 4D6WA 2YT0A 4IOYX 2KGXB 1U5FA 1OQNA 3KY9A 4DX8A 4CHJA 5I2SA 2EJ8A 1FHWA 1X11A 4WJ7A 2LKOA 4KHBA 1WJ1A 2D2QA 2DX1A 5HE1A 1U27A 1SGHA 4WVFB 3AU5A 2DYQA 2K2JA 1BWNA 1DDWA 2P0FA 3D8FA 4QXAB 5M4YB 1FOEA 2KIEA 2D11A 2J0JA 2UZSA 2RUKB 4K17A 1GC7A 2Z0OA 4HAWB 4F7GA 1QC6A 3PVLA 3F5RA 5KQ1A 4QJ5B 1UNQA 5DHAB 1V88A 3DXDA 5D3XA 2R09A 1MKEA 2QKMA 2BCJA 2COAA 3PP2A 2UVMA 3SV1A 3WA0A 1H10A 4MT7A 3KRWA 2Z0PA 3IVFA 1MK9B 4A6KA 4A5KA 1MIZB 3KZ1A 1K5GB 1XKEA 2EMTA 4Z2NA 2YF0A 2D4QA 2V76A 2Y8GA 1AQCA 1P3RA 5JHHA 1NI2A 5HE0A 1BAKA 2EC1A 3ULBA 2GUMA 3LJUX 2K2UA 4GN1A 1LB1A 4XWXA 4F7HA 5CLLB 3ZDTA 1KZGA 3PZDA 2RSGA 3PG7A 2YS3A 1AWEA 1GG3A 2XQNM 2RRFA 1KI1B 1DDVA 1UPRA 3FSSA 4HAZB 2NMBA 3BINA 3UZTA 1IRSA 2DYNA 4A6FB 2CRFA 1UEFA 1M7RA 4MY6A 2GS0A 5KQ4A 3BJIA 1TXDA 2CODA 2DKPA 2Z4DA 3DCXA 3O96A 4A6FA 1W1GA 1ZSQA 2UZRA 2M14A 2RGNB 4EJNA 4PQ0A 2KIGA 1ISNA
chains in the Genus database with same CATH topology
5J3QA 2VSZA 2E2XA 4KVGB 2ZPYA 3FEHA 2YSZA 1E5WA 3FM8C 3PEGA 2IYBA 4HATB 1RJ2A 2LULA 3T06A 1V61A 1NTVA 2GCJA 2P0HA 3NSUA 2I5CA 1WGUA 1X05A 1PFJA 3CIKA 2YVCA 3OANA 5C5BB 2VRWB 2DN6A 4KHAA 2W2XD 4Z2MB 1FGYA 1ZC3B 1ZM0A 2DHIA 2YT1A 1U29A 2JP2A 1NU2A 1M7EA 5C5BA 1FHXA 1U2BA 1Y19B 3V5WA 2R0DA 2DFKA 1RRPB 2MDXA 4GPTB 4GXBA 5D3WA 3ODOA 1J0WA 5D27A 2J0KA 2RNRB 5HE3A 2L1CA 4DXAB 1ZC4B 2AEHA 3P6AA 3ML4A 3PSCA 1TJ6A 3ZVRA 5C79A 3MDBC 3GYPA 3HW2B 5JHGA 1XODA 2P0DA 4K81A 2KCJA 2D9XA 3M1IB 2DA0A 2W2XC 4ZRIA 1UPQA 1V89A 2Z0QA 2W2WA 1X1FA 3DXCA 5DI9B 5JP4A 1ZVRA 2ELBA 3TVVA 1P6SA 4DX90 4H8SA 2AL6A 2D9YA 5L81A 1MIXA 1DDMA 4HDOA 1P5TA 3VIAA 4Y94A 5J3TA 3SO6A 3ULCA 4TYZA 5DH9B 4D0NB 5EFXA 3X23A 2DTCA 1Q67A 4YL8A 3U7DA 3QIJA 2I1JA 3HK0A 1U5GA 2Q13A 1FGZA 3TFMA 3KSYA 3D8DA 5JLJB 4ZRKA 2QKLA 2FJLA 3QWMA 3ODWA 4KAXB 1WI1A 2D9ZA 3SNHA 2N0YA 1OMWA 2G35A 2L2IA 2ROVA 3G9WA 2CAYA 2GJYA 3MPXA 2LOZA 2Y8FA 3TCAA 4KHOA 3D8EA 2H7EA 5LONB 5FI1A 2DHJA 4P7IA 4EKUA 4IFSA 4WSFA 2M38A 1UNRA 2LOXA 1U5DA 1V5PA 5C16A 1DBHA 2LYDA 1J19A 3N7CA 2LG1A 3SYXA 1NTYA 1DROA 2HTHB 5LOPB 5GOWB 2GCLA 2CY5A 4L6EA 4CYEA 1BTKA 4HB2B 1W1DA 2I5FA 4C0AA 4HAXB 3A8PA 1OY2A 4EMOA 1EVHA 3TO1A 1FB8A 2Y7BA 4IAPA 1H4RA 3AU4A 2N23A 2D9VA 3U8ZA 2DHKA 1XCGA 1N3HA 2CY4A 1FAOA 2RLOA 3HQCA 2ELAA 5KCVA 2MWNB 4MK0A 1V5MA 4BBKA 4DBBA 1KZ7A 1UNPA 1WGQA 1EF1A 1XR0B 3DXEA 1U5EA 1LW3A 2J0MA 1BTNA 4PNKA 2KUPA 5D3YA 3QBVB 4ZRJA 1WVHA 4HB3B 1X86A 1EAZA 3TW1A 3P7ZA 2DKQA 2DLWA 3CXBB 4NY0A 2OTXA 3GYOA 4HAVB 2ADZA 4CHMA 3ODXA 5DIFB 2J59M 3KRXA 4GMVA 1QQGA 3PVWA 2H7DA 5FI0A 4NSWA 4K2PA 4HB4B 4HAUB 2PZ1A 4HB0B 2IFSA 2D9WA 4GZUA 3RCPA 3A8QA 1WG7A 3WYFB 4HAYB 1Y5OA 2K00A 1I2HA 4B6HA 5C6RA 1PMSA 2COFA 2DX5A 5HE2A 1TQZA 4GMXB 1I7AA 4HHVA 3PVUA 2EMSA 2OQBA 3F0WA 1XX0A 2ROZB 2P8VA 4A6HA 2MFQA 2RVBB 1B55A 1WJMA 2HE7A 4YONA 2COCA 2MKRA 5DHFB 5J3YA 2D10A 2YRYA 2YS5A 2I1KA 3SUZA 1XD4A 1FHOA 1MPHA 1V5UA 1SHCA 3VOQA 4F7UP 1K5DB 1EGXA 1MAIA 2NZ8B 5CLQB 1Z87A 1GC6A 1W1HA 2YS1A 3A98B 1X1GA 2X18A 1MK7B 4TKNA 2VKIA 1DYNA 4HDQA 4K2OA 3AJ4A 4KHBB 1PLSA 5D3VA 2YT0A 4IOYX 2KGXB 1U5FA 1OQNA 3KY9A 4DX8A 4CHJA 2EJ8A 1FHWA 1X11A 4WJ7A 2LKOA 1WJ1A 2D2QA 2DX1A 5HE1A 1U27A 1SGHA 4WVFB 3AU5A 2DYQA 2K2JA 1BWNA 1DDWA 2P0FA 3D8FA 1FOEA 2D11A 2J0JA 2UZSA 2RUKB 4K17A 1GC7A 2Z0OA 4HAWB 4F7GA 1QC6A 3PVLA 3F5RA 5KQ1A 1UNQA 5DHAB 1V88A 3DXDA 5D3XA 2R09A 1MKEA 2QKMA 2BCJA 2COAA 3PP2A 2UVMA 3SV1A 3WA0A 1H10A 4MT7A 3KRWA 2Z0PA 3IVFA 1MK9B 4A6KA 4A5KA 1MIZB 3KZ1A 1K5GB 1XKEA 2EMTA 4Z2NA 2YF0A 2D4QA 2V76A 2Y8GA 1AQCA 1P3RA 5JHHA 1NI2A 5HE0A 1BAKA 2EC1A 3ULBA 3LJUX 2K2UA 4GN1A 1LB1A 4XWXA 4F7HA 5CLLB 3ZDTA 1KZGA 3PZDA 2RSGA 3PG7A 2YS3A 1AWEA 1GG3A 2XQNM 1KI1B 1DDVA 1UPRA 3FSSA 4HAZB 2NMBA 3BINA 3UZTA 1IRSA 2DYNA 4A6FB 2CRFA 1UEFA 1M7RA 4MY6A 2GS0A 5KQ4A 3BJIA 1TXDA 2CODA 2DKPA 3O96A 4A6FA 1W1GA 1ZSQA 2UZRA 2M14A 2RGNB 4EJNA 4PQ0A 1ISNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5J3Q A;  2VSZ A;  2E2X A;  4KVG B;  2ZPY A;  3FEH A;  2YSZ A;  1E5W A;  3FM8 C;  3PEG A;  2IYB A;  4HAT B;  1RJ2 A;  2LUL A;  3T06 A;  1V61 A;  1NTV A;  2GCJ A;  2P0H A;  3NSU A;  2I5C A;  1WGU A;  1X05 A;  1PFJ A;  3CIK A;  2YVC A;  3OAN A;  5C5B B;  2VRW B;  2DN6 A;  4KHA A;  2W2X D;  4Z2M B;  1FGY A;  1ZC3 B;  1ZM0 A;  2DHI A;  2YT1 A;  1U29 A;  2JP2 A;  1NU2 A;  1M7E A;  5C5B A;  1FHX A;  1U2B A;  1Y19 B;  3V5W A;  2R0D A;  2DFK A;  1RRP B;  2MDX A;  4GPT B;  4GXB A;  5D3W A;  3ODO A;  1J0W A;  5D27 A;  2J0K A;  2RNR B;  5HE3 A;  2L1C A;  4DXA B;  1ZC4 B;  2AEH A;  3P6A A;  3ML4 A;  3PSC A;  1TJ6 A;  3ZVR A;  5C79 A;  3MDB C;  3GYP A;  3HW2 B;  5JHG A;  1XOD A;  2P0D A;  4K81 A;  2KCJ A;  2D9X A;  3M1I B;  2DA0 A;  2W2X C;  4ZRI A;  1UPQ A;  1V89 A;  2Z0Q A;  2W2W A;  1X1F A;  3DXC A;  5DI9 B;  5JP4 A;  1ZVR A;  2ELB A;  3TVV A;  1P6S A;  4DX9 0;  4H8S A;  2AL6 A;  2D9Y A;  5L81 A;  1MIX A;  1DDM A;  4HDO A;  1P5T A;  3VIA A;  4Y94 A;  5J3T A;  3SO6 A;  3ULC A;  4TYZ A;  5DH9 B;  4D0N B;  5EFX A;  3X23 A;  2DTC A;  1Q67 A;  4YL8 A;  3U7D A;  3QIJ A;  2I1J A;  3HK0 A;  1U5G A;  2Q13 A;  1FGZ A;  3TFM A;  3KSY A;  3D8D A;  5JLJ B;  4ZRK A;  2QKL A;  2FJL A;  3QWM A;  3ODW A;  4KAX B;  1WI1 A;  2D9Z A;  3SNH A;  2N0Y A;  1OMW A;  2G35 A;  2L2I A;  2ROV A;  3G9W A;  2CAY A;  2GJY A;  3MPX A;  2LOZ A;  2Y8F A;  3TCA A;  4KHO A;  3D8E A;  2H7E A;  5LON B;  5FI1 A;  2DHJ A;  4P7I A;  4EKU A;  4IFS A;  4WSF A;  2M38 A;  1UNR A;  2LOX A;  1U5D A;  1V5P A;  5C16 A;  1DBH A;  2LYD A;  1J19 A;  3N7C A;  2LG1 A;  3SYX A;  1NTY A;  1DRO A;  2HTH B;  5LOP B;  5GOW B;  2GCL A;  2CY5 A;  4L6E A;  4CYE A;  1BTK A;  4HB2 B;  1W1D A;  2I5F A;  4C0A A;  4HAX B;  3A8P A;  1OY2 A;  4EMO A;  1EVH A;  3TO1 A;  1FB8 A;  2Y7B A;  4IAP A;  1H4R A;  3AU4 A;  2N23 A;  2D9V A;  3U8Z A;  2DHK A;  1XCG A;  1N3H A;  2CY4 A;  1FAO A;  2RLO A;  3HQC A;  2ELA A;  5KCV A;  2MWN B;  4MK0 A;  1V5M A;  4BBK A;  4DBB A;  1KZ7 A;  1UNP A;  1WGQ A;  1EF1 A;  1XR0 B;  3DXE A;  1U5E A;  1LW3 A;  2J0M A;  1BTN A;  4PNK A;  2KUP A;  5D3Y A;  3QBV B;  4ZRJ A;  1WVH A;  4HB3 B;  1X86 A;  1EAZ A;  3TW1 A;  3P7Z A;  2DKQ A;  2DLW A;  3CXB B;  4NY0 A;  2OTX A;  3GYO A;  4HAV B;  2ADZ A;  4CHM A;  3ODX A;  5DIF B;  2J59 M;  3KRX A;  4GMV A;  1QQG A;  3PVW A;  2H7D A;  5FI0 A;  4NSW A;  4K2P A;  4HB4 B;  4HAU B;  2PZ1 A;  4HB0 B;  2IFS A;  2D9W A;  4GZU A;  3RCP A;  3A8Q A;  1WG7 A;  3WYF B;  4HAY B;  1Y5O A;  2K00 A;  1I2H A;  4B6H A;  5C6R A;  1PMS A;  2COF A;  2DX5 A;  5HE2 A;  1TQZ A;  4GMX B;  1I7A A;  4HHV A;  3PVU A;  2EMS A;  2OQB A;  3F0W A;  1XX0 A;  2ROZ B;  2P8V A;  4A6H A;  2MFQ A;  2RVB B;  1B55 A;  1WJM A;  2HE7 A;  4YON A;  2COC A;  2MKR A;  5DHF B;  5J3Y A;  2D10 A;  2YRY A;  2YS5 A;  2I1K A;  3SUZ A;  1XD4 A;  1FHO A;  1MPH A;  1V5U A;  1SHC A;  3VOQ A;  4F7U P;  1K5D B;  1EGX A;  1MAI A;  2NZ8 B;  5CLQ B;  1Z87 A;  1GC6 A;  1W1H A;  2YS1 A;  3A98 B;  1X1G A;  2X18 A;  1MK7 B;  4TKN A;  2VKI A;  1DYN A;  4HDQ A;  4K2O A;  3AJ4 A;  4KHB B;  1PLS A;  5D3V A;  2YT0 A;  4IOY X;  2KGX B;  1U5F A;  1OQN A;  3KY9 A;  4DX8 A;  4CHJ A;  2EJ8 A;  1FHW A;  1X11 A;  4WJ7 A;  2LKO A;  1WJ1 A;  2D2Q A;  2DX1 A;  5HE1 A;  1U27 A;  1SGH A;  4WVF B;  3AU5 A;  2DYQ A;  2K2J A;  1BWN A;  1DDW A;  2P0F A;  3D8F A;  1FOE A;  2D11 A;  2J0J A;  2UZS A;  2RUK B;  4K17 A;  1GC7 A;  2Z0O A;  4HAW B;  4F7G A;  1QC6 A;  3PVL A;  3F5R A;  5KQ1 A;  1UNQ A;  5DHA B;  1V88 A;  3DXD A;  5D3X A;  2R09 A;  1MKE A;  2QKM A;  2BCJ A;  2COA A;  3PP2 A;  2UVM A;  3SV1 A;  3WA0 A;  1H10 A;  4MT7 A;  3KRW A;  2Z0P A;  3IVF A;  1MK9 B;  4A6K A;  4A5K A;  1MIZ B;  3KZ1 A;  1K5G B;  1XKE A;  2EMT A;  4Z2N A;  2YF0 A;  2D4Q A;  2V76 A;  2Y8G A;  1AQC A;  1P3R A;  5JHH A;  1NI2 A;  5HE0 A;  1BAK A;  2EC1 A;  3ULB A;  3LJU X;  2K2U A;  4GN1 A;  1LB1 A;  4XWX A;  4F7H A;  5CLL B;  3ZDT A;  1KZG A;  3PZD A;  2RSG A;  3PG7 A;  2YS3 A;  1AWE A;  1GG3 A;  2XQN M;  1KI1 B;  1DDV A;  1UPR A;  3FSS A;  4HAZ B;  2NMB A;  3BIN A;  3UZT A;  1IRS A;  2DYN A;  4A6F B;  2CRF A;  1UEF A;  1M7R A;  4MY6 A;  2GS0 A;  5KQ4 A;  3BJI A;  1TXD A;  2COD A;  2DKP A;  3O96 A;  4A6F A;  1W1G A;  1ZSQ A;  2UZR A;  2M14 A;  2RGN B;  4EJN A;  4PQ0 A;  1ISN A; 
#chains in the Genus database with same CATH topology
 5J3Q A;  2VSZ A;  2E2X A;  4KVG B;  2ZPY A;  3FEH A;  2YSZ A;  1E5W A;  4DIX A;  3FM8 C;  3PEG A;  2IYB A;  4HAT B;  1RJ2 A;  2LUL A;  2K49 A;  3T06 A;  1V61 A;  1NTV A;  2GCJ A;  2P0H A;  3NSU A;  2I5C A;  2Z13 A;  1WGU A;  1X05 A;  1PFJ A;  3CIK A;  2YVC A;  1ZYI A;  5I2M A;  3OAN A;  5C5B B;  2VRW B;  2DN6 A;  4KHA A;  2W2X D;  4Z2M B;  1FGY A;  1ZC3 B;  1ZM0 A;  2DHI A;  2YT1 A;  1U29 A;  2JP2 A;  1NU2 A;  1M7E A;  5C5B A;  1FHX A;  1U2B A;  1Y19 B;  3V5W A;  2R0D A;  2DFK A;  1RRP B;  2MDX A;  4GPT B;  4GXB A;  5D3W A;  2FJU B;  3ODO A;  1J0W A;  5D27 A;  2J0K A;  3FVC A;  2RNR B;  4OT1 A;  5HE3 A;  2L1C A;  4DXA B;  1ZC4 B;  2AEH A;  5LG4 B;  3P6A A;  5IRS A;  3ML4 A;  3PSC A;  1TJ6 A;  4OSN A;  4HSI A;  3ZVR A;  5C79 A;  3MDB C;  3GYP A;  3HW2 B;  5JHG A;  1XOD A;  2P0D A;  4K81 A;  2KCJ A;  2D9X A;  3M1I B;  2DA0 A;  2W2X C;  4ZRI A;  1UPQ A;  1V89 A;  2Z0Q A;  2W2W A;  1X1F A;  3DXC A;  5DI9 B;  5JP4 A;  1ZVR A;  2ELB A;  3TVV A;  1P6S A;  4DX9 0;  2Z14 A;  4H8S A;  2AL6 A;  2D9Y A;  5L81 A;  1MIX A;  1DDM A;  3NW8 A;  4HDO A;  1P5T A;  3VIA A;  4Y94 A;  5J3T A;  3HIE A;  3SO6 A;  3ULC A;  4TYZ A;  5DH9 B;  4D0N B;  5EFX A;  3X23 A;  2DTC A;  1Q67 A;  4YL8 A;  4QJ3 B;  3U7D A;  3QIJ A;  2I1J A;  3HK0 A;  3NWA A;  1U5G A;  2Q13 A;  1FGZ A;  3TFM A;  3KSY A;  3D8D A;  2KUQ A;  3NWF A;  5JLJ B;  2YT2 A;  2QKL A;  4ZRK A;  2FJL A;  4GOU A;  3QWM A;  3ODW A;  4KAX B;  1WI1 A;  2D9Z A;  2R2Y A;  3SNH A;  2N0Y A;  1OMW A;  4L1R A;  2G35 A;  2L2I A;  2ROV A;  3G9W A;  2CAY A;  2GJY A;  3MPX A;  2LOZ A;  2Y8F A;  3TCA A;  4KHO A;  3D8E A;  2H7E A;  5LON B;  5FI1 A;  2DHJ A;  2ZKM X;  4P7I A;  4EKU A;  4IFS A;  4WSF A;  2M38 A;  1UNR A;  2LOX A;  1U5D A;  1V5P A;  5C16 A;  1DBH A;  2LYD A;  1J19 A;  3N7C A;  2LG1 A;  3SYX A;  1NTY A;  1DRO A;  2HTH B;  5LOP B;  5GOW B;  3U12 A;  2GCL A;  2CY5 A;  4L6E A;  2K8E A;  4CYE A;  1BTK A;  4HB2 B;  1W1D A;  2I5F A;  1T77 A;  4C0A A;  4HAX B;  3A8P A;  1OY2 A;  4EMO A;  1EVH A;  3TO1 A;  1FB8 A;  2Y7B A;  4IAP A;  1H4R A;  3AU4 A;  2N23 A;  2D9V A;  3U8Z A;  2DHK A;  1XCG A;  1N3H A;  2CY4 A;  1FAO A;  2RLO A;  3HQC A;  2ELA A;  5KCV A;  2MWN B;  4MK0 A;  1V5M A;  4BBK A;  4DBB A;  1KZ7 A;  1UNP A;  1WGQ A;  2KR0 A;  1EF1 A;  1XR0 B;  3DXE A;  1U5E A;  1LW3 A;  2J0M A;  1BTN A;  4PNK A;  2KUP A;  5D3Y A;  3QBV B;  4ZRJ A;  1WVH A;  4HB3 B;  1X86 A;  1EAZ A;  3TW1 A;  3P7Z A;  2DKQ A;  2DLW A;  3CXB B;  4NY0 A;  2OTX A;  3GYO A;  4HAV B;  3A58 A;  2ADZ A;  4CHM A;  3B77 A;  3ODX A;  5DIF B;  2J59 M;  3OHM B;  3KRX A;  3HSA A;  4GMV A;  1QQG A;  3PVW A;  2H7D A;  5FI0 A;  4CSQ A;  4NSW A;  4K2P A;  4HB4 B;  3NWD A;  4HAU B;  2PZ1 A;  4HB0 B;  2IFS A;  4QJ4 B;  2D9W A;  4GZU A;  3RCP A;  3A8Q A;  1WG7 A;  3WYF B;  4HAY B;  1Y5O A;  2K00 A;  1MI1 A;  1I2H A;  4B6H A;  5C6R A;  1PMS A;  2COF A;  2DX5 A;  5HE2 A;  1TQZ A;  4GMX B;  1I7A A;  4HHV A;  3PVU A;  2EMS A;  2OQB A;  3F0W A;  1XX0 A;  2ROZ B;  2P8V A;  4A6H A;  2MFQ A;  2RVB B;  4GNK B;  1B55 A;  1WJM A;  2HE7 A;  4YON A;  2COC A;  2MKR A;  5DHF B;  2NBV A;  5J3Y A;  2D10 A;  2YRY A;  2YS5 A;  2I1K A;  3SUZ A;  1XD4 A;  1FHO A;  1MPH A;  1V5U A;  1SHC A;  3VOQ A;  4F7U P;  1K5D B;  1EGX A;  1MAI A;  2NZ8 B;  5CLQ B;  1Z87 A;  1GC6 A;  1W1H A;  2YS1 A;  3A98 B;  1X1G A;  2X18 A;  1MK7 B;  4TKN A;  2VKI A;  1DYN A;  4HDQ A;  4K2O A;  2Z59 A;  3AJ4 A;  4KHB B;  1PLS A;  5D3V A;  4D6W A;  2YT0 A;  4IOY X;  2KGX B;  1U5F A;  1OQN A;  3KY9 A;  4DX8 A;  4CHJ A;  5I2S A;  2EJ8 A;  1FHW A;  1X11 A;  4WJ7 A;  2LKO A;  4KHB A;  1WJ1 A;  2D2Q A;  2DX1 A;  5HE1 A;  1U27 A;  1SGH A;  4WVF B;  3AU5 A;  2DYQ A;  2K2J A;  1BWN A;  1DDW A;  2P0F A;  3D8F A;  4QXA B;  5M4Y B;  1FOE A;  2KIE A;  2D11 A;  2J0J A;  2UZS A;  2RUK B;  4K17 A;  1GC7 A;  2Z0O A;  4HAW B;  4F7G A;  1QC6 A;  3PVL A;  3F5R A;  5KQ1 A;  4QJ5 B;  1UNQ A;  5DHA B;  1V88 A;  3DXD A;  5D3X A;  2R09 A;  1MKE A;  2QKM A;  2BCJ A;  2COA A;  3PP2 A;  2UVM A;  3SV1 A;  3WA0 A;  1H10 A;  4MT7 A;  3KRW A;  2Z0P A;  3IVF A;  1MK9 B;  4A6K A;  4A5K A;  1MIZ B;  3KZ1 A;  1K5G B;  1XKE A;  2EMT A;  4Z2N A;  2YF0 A;  2D4Q A;  2V76 A;  2Y8G A;  1AQC A;  1P3R A;  5JHH A;  1NI2 A;  5HE0 A;  1BAK A;  2EC1 A;  3ULB A;  2GUM A;  3LJU X;  2K2U A;  4GN1 A;  1LB1 A;  4XWX A;  4F7H A;  5CLL B;  3ZDT A;  1KZG A;  3PZD A;  2RSG A;  3PG7 A;  2YS3 A;  1AWE A;  1GG3 A;  2XQN M;  2RRF A;  1KI1 B;  1DDV A;  1UPR A;  3FSS A;  4HAZ B;  2NMB A;  3BIN A;  3UZT A;  1IRS A;  2DYN A;  4A6F B;  2CRF A;  1UEF A;  1M7R A;  4MY6 A;  2GS0 A;  5KQ4 A;  3BJI A;  1TXD A;  2COD A;  2DKP A;  2Z4D A;  3DCX A;  3O96 A;  4A6F A;  1W1G A;  1ZSQ A;  2UZR A;  2M14 A;  2RGN B;  4EJN A;  4PQ0 A;  2KIG A;  1ISN A; 
#chains in the Genus database with same CATH homology
 5J3Q A;  2VSZ A;  2E2X A;  4KVG B;  2ZPY A;  3FEH A;  2YSZ A;  1E5W A;  3FM8 C;  3PEG A;  2IYB A;  4HAT B;  1RJ2 A;  2LUL A;  3T06 A;  1V61 A;  1NTV A;  2GCJ A;  2P0H A;  3NSU A;  2I5C A;  1WGU A;  1X05 A;  1PFJ A;  3CIK A;  2YVC A;  3OAN A;  5C5B B;  2VRW B;  2DN6 A;  4KHA A;  2W2X D;  4Z2M B;  1FGY A;  1ZC3 B;  1ZM0 A;  2DHI A;  2YT1 A;  1U29 A;  2JP2 A;  1NU2 A;  1M7E A;  5C5B A;  1FHX A;  1U2B A;  1Y19 B;  3V5W A;  2R0D A;  2DFK A;  1RRP B;  2MDX A;  4GPT B;  4GXB A;  5D3W A;  3ODO A;  1J0W A;  5D27 A;  2J0K A;  2RNR B;  5HE3 A;  2L1C A;  4DXA B;  1ZC4 B;  2AEH A;  3P6A A;  3ML4 A;  3PSC A;  1TJ6 A;  3ZVR A;  5C79 A;  3MDB C;  3GYP A;  3HW2 B;  5JHG A;  1XOD A;  2P0D A;  4K81 A;  2KCJ A;  2D9X A;  3M1I B;  2DA0 A;  2W2X C;  4ZRI A;  1UPQ A;  1V89 A;  2Z0Q A;  2W2W A;  1X1F A;  3DXC A;  5DI9 B;  5JP4 A;  1ZVR A;  2ELB A;  3TVV A;  1P6S A;  4DX9 0;  4H8S A;  2AL6 A;  2D9Y A;  5L81 A;  1MIX A;  1DDM A;  4HDO A;  1P5T A;  3VIA A;  4Y94 A;  5J3T A;  3SO6 A;  3ULC A;  4TYZ A;  5DH9 B;  4D0N B;  5EFX A;  3X23 A;  2DTC A;  1Q67 A;  4YL8 A;  3U7D A;  3QIJ A;  2I1J A;  3HK0 A;  1U5G A;  2Q13 A;  1FGZ A;  3TFM A;  3KSY A;  3D8D A;  5JLJ B;  4ZRK A;  2QKL A;  2FJL A;  3QWM A;  3ODW A;  4KAX B;  1WI1 A;  2D9Z A;  3SNH A;  2N0Y A;  1OMW A;  2G35 A;  2L2I A;  2ROV A;  3G9W A;  2CAY A;  2GJY A;  3MPX A;  2LOZ A;  2Y8F A;  3TCA A;  4KHO A;  3D8E A;  2H7E A;  5LON B;  5FI1 A;  2DHJ A;  4P7I A;  4EKU A;  4IFS A;  4WSF A;  2M38 A;  1UNR A;  2LOX A;  1U5D A;  1V5P A;  5C16 A;  1DBH A;  2LYD A;  1J19 A;  3N7C A;  2LG1 A;  3SYX A;  1NTY A;  1DRO A;  2HTH B;  5LOP B;  5GOW B;  2GCL A;  2CY5 A;  4L6E A;  4CYE A;  1BTK A;  4HB2 B;  1W1D A;  2I5F A;  4C0A A;  4HAX B;  3A8P A;  1OY2 A;  4EMO A;  1EVH A;  3TO1 A;  1FB8 A;  2Y7B A;  4IAP A;  1H4R A;  3AU4 A;  2N23 A;  2D9V A;  3U8Z A;  2DHK A;  1XCG A;  1N3H A;  2CY4 A;  1FAO A;  2RLO A;  3HQC A;  2ELA A;  5KCV A;  2MWN B;  4MK0 A;  1V5M A;  4BBK A;  4DBB A;  1KZ7 A;  1UNP A;  1WGQ A;  1EF1 A;  1XR0 B;  3DXE A;  1U5E A;  1LW3 A;  2J0M A;  1BTN A;  4PNK A;  2KUP A;  5D3Y A;  3QBV B;  4ZRJ A;  1WVH A;  4HB3 B;  1X86 A;  1EAZ A;  3TW1 A;  3P7Z A;  2DKQ A;  2DLW A;  3CXB B;  4NY0 A;  2OTX A;  3GYO A;  4HAV B;  2ADZ A;  4CHM A;  3ODX A;  5DIF B;  2J59 M;  3KRX A;  4GMV A;  1QQG A;  3PVW A;  2H7D A;  5FI0 A;  4NSW A;  4K2P A;  4HB4 B;  4HAU B;  2PZ1 A;  4HB0 B;  2IFS A;  2D9W A;  4GZU A;  3RCP A;  3A8Q A;  1WG7 A;  3WYF B;  4HAY B;  1Y5O A;  2K00 A;  1I2H A;  4B6H A;  5C6R A;  1PMS A;  2COF A;  2DX5 A;  5HE2 A;  1TQZ A;  4GMX B;  1I7A A;  4HHV A;  3PVU A;  2EMS A;  2OQB A;  3F0W A;  1XX0 A;  2ROZ B;  2P8V A;  4A6H A;  2MFQ A;  2RVB B;  1B55 A;  1WJM A;  2HE7 A;  4YON A;  2COC A;  2MKR A;  5DHF B;  5J3Y A;  2D10 A;  2YRY A;  2YS5 A;  2I1K A;  3SUZ A;  1XD4 A;  1FHO A;  1MPH A;  1V5U A;  1SHC A;  3VOQ A;  4F7U P;  1K5D B;  1EGX A;  1MAI A;  2NZ8 B;  5CLQ B;  1Z87 A;  1GC6 A;  1W1H A;  2YS1 A;  3A98 B;  1X1G A;  2X18 A;  1MK7 B;  4TKN A;  2VKI A;  1DYN A;  4HDQ A;  4K2O A;  3AJ4 A;  4KHB B;  1PLS A;  5D3V A;  2YT0 A;  4IOY X;  2KGX B;  1U5F A;  1OQN A;  3KY9 A;  4DX8 A;  4CHJ A;  2EJ8 A;  1FHW A;  1X11 A;  4WJ7 A;  2LKO A;  1WJ1 A;  2D2Q A;  2DX1 A;  5HE1 A;  1U27 A;  1SGH A;  4WVF B;  3AU5 A;  2DYQ A;  2K2J A;  1BWN A;  1DDW A;  2P0F A;  3D8F A;  1FOE A;  2D11 A;  2J0J A;  2UZS A;  2RUK B;  4K17 A;  1GC7 A;  2Z0O A;  4HAW B;  4F7G A;  1QC6 A;  3PVL A;  3F5R A;  5KQ1 A;  1UNQ A;  5DHA B;  1V88 A;  3DXD A;  5D3X A;  2R09 A;  1MKE A;  2QKM A;  2BCJ A;  2COA A;  3PP2 A;  2UVM A;  3SV1 A;  3WA0 A;  1H10 A;  4MT7 A;  3KRW A;  2Z0P A;  3IVF A;  1MK9 B;  4A6K A;  4A5K A;  1MIZ B;  3KZ1 A;  1K5G B;  1XKE A;  2EMT A;  4Z2N A;  2YF0 A;  2D4Q A;  2V76 A;  2Y8G A;  1AQC A;  1P3R A;  5JHH A;  1NI2 A;  5HE0 A;  1BAK A;  2EC1 A;  3ULB A;  3LJU X;  2K2U A;  4GN1 A;  1LB1 A;  4XWX A;  4F7H A;  5CLL B;  3ZDT A;  1KZG A;  3PZD A;  2RSG A;  3PG7 A;  2YS3 A;  1AWE A;  1GG3 A;  2XQN M;  1KI1 B;  1DDV A;  1UPR A;  3FSS A;  4HAZ B;  2NMB A;  3BIN A;  3UZT A;  1IRS A;  2DYN A;  4A6F B;  2CRF A;  1UEF A;  1M7R A;  4MY6 A;  2GS0 A;  5KQ4 A;  3BJI A;  1TXD A;  2COD A;  2DKP A;  3O96 A;  4A6F A;  1W1G A;  1ZSQ A;  2UZR A;  2M14 A;  2RGN B;  4EJN A;  4PQ0 A;  1ISN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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