The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
63
|
sequence length |
286
|
structure length |
286
|
Chain Sequence |
RLIYTAGGYFRQSLSYLEAYNPSDGTWLDLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVTLE
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Binding Mode and Structure-Activity Relationships around Direct Inhibitors of the Nrf2-Keap1 Complex.
pubmed doi rcsb |
| molecule tags |
Transcription/inhibitor
|
| source organism |
Homo sapiens
|
| molecule keywords |
Kelch-like ECH-associated protein 1
|
| total genus |
63
|
| structure length |
286
|
| sequence length |
286
|
| chains with identical sequence |
B, C
|
| ec nomenclature | |
| pdb deposition date | 2013-06-13 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF01344 | Kelch_1 | Kelch motif |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | 6 Propeller | Neuraminidase | Kelch-type beta propeller |
#chains in the Genus database with same CATH superfamily 4CHB A; 4ASC A; 5FNR A; 4ZY3 A; 2FLU X; 5FNT A; 5FZN A; 1ZGK A; 2XN4 A; 3VNH A; 3WN7 A; 4N1B A; 4ZGC A; 4IN4 A; 1X2J A; 2WOZ A; 2ZWA A; 5FZJ A; 2VPJ A; 1U6D X; 3ZGC A; 5FNU A; 3WDZ A; 2Z32 A; 4L7D A; 4YY8 A; 4IFJ A; 4IFN X; 3ADE A; 3II7 A; 4IQK A; 5FNS A; 4IFL X; 5FNQ A; 2ZW9 A; 5F72 C; 4L7B A; 4L7C A; 3ZGD A; 3VNG A; 4XMB A; 2DYH A; 4CH9 A; 2ZZK A; 1X2R A; 5CGJ A; #chains in the Genus database with same CATH topology 1N7D A; 3KGG A; 4GDI A; 2ISM A; 1WCQ A; 1DIL A; 2F26 A; 4FPO B; 1MS3 A; 4FPY A; 5FNU A; 1SUU A; 5F9T A; 3Q6P A; 4GNB A; 4AHA A; 4FPF A; 4GJT A; 5FNS A; 4IYG A; 3CL2 A; 3A72 A; 4H52 A; 2W5O A; 3S8V A; 4A0P A; 2IAP A; 4FPK A; 4QN4 A; 3O9J A; 2OJH A; 2XZJ A; 1WCS A; 4ASC A; 1V3D A; 2FP8 A; 3S2K A; 1EUR A; 4XOG A; 1X2J A; 4GZO A; 2BER A; 1MZ5 A; 4FPG A; 3B7E A; 1MS0 A; 1F8C A; 4O5S A; 4K1H A; 3CKZ A; 2QWH A; 5EO8 A; 4MZA A; 4YZ3 A; 2B8H A; 1NNA A; 1C9U A; 4MX0 A; 4L7C A; 4XJQ A; 1MS9 A; 4NN9 A; 2YA6 A; 4FOW A; 3P5B L; 5EX7 A; 5H47 A; 1V0E A; 4MWY A; 2HTU A; 3TI3 A; 5FNT A; 5FZN A; 4YW4 A; 2IAQ A; 3G4H A; 4Q1U A; 3I1C A; 2BAT A; 5D9B A; 3V1S A; 1NPE A; 2GVV A; 4MZE A; 4FOQ A; 4IQK A; 1EUU A; 4MC7 A; 4YW1 A; 1IUB A; 3NO0 A; 4MWV A; 4L7B A; 3Q6T A; 3SAN A; 2QE8 A; 2HT5 A; 3O4P A; 1V3B A; 4K1K A; 2FPC A; 4WEF A; 4PWZ A; 5GX4 A; 5GX2 A; 1SO7 A; 4CHB A; 1W0P A; 2FP9 A; 2QWC A; 1NCA N; 4X47 A; 4KS1 A; 2XN4 A; 3Q6K A; 3S94 A; 4X49 A; 2VPJ A; 2IAV A; 4GZQ A; 2VK7 A; 2XCY A; 2QWE A; 4YZ1 A; 3HLI A; 2ZB5 A; 3G4E A; 1E8T A; 3IAX A; 4XMI A; 3KYA A; 4QNP A; 5NN9 A; 5F72 C; 4MWW A; 2H2U A; 3INB A; 4XYX A; 4CPN A; 1B9V A; 5HUG A; 1IVE A; 4B7M A; 3GVL A; 5HUM A; 4XJA A; 2VWD A; 4YZ4 A; 5GX3 A; 3BEQ A; 1N6F A; 5FZJ A; 4HHQ A; 1WP5 A; 3SAL A; 1C5K A; 1F8D A; 2GVW A; 1CRU A; 1XOE A; 4YW3 A; 4GZT A; 1F8B A; 2QWK A; 1SLL A; 4WA3 A; 4M4U A; 2C4L A; 1CQ1 A; 2W8B B; 4GN9 A; 4XMB A; 4GNC A; 4XJ8 A; 2FHR A; 4XHB A; 5HUK A; 4YW2 A; 1N6E A; 3LI4 A; 3TI5 A; 3HLH A; 1ZGK A; 3WN7 A; 3D12 A; 2IVZ A; 4XIO A; 1NMB N; 4WEG A; 2WOZ A; 4FJ6 A; 4UOU A; 4MWJ A; 3SOB B; 4QN3 A; 3AMS A; 1V04 A; 4YZ5 A; 4YY8 A; 2F13 A; 5HX0 A; 4MWU A; 3SIL A; 4FPH A; 1S0J A; 3TI8 A; 4AH4 A; 4CPY A; 3ALW A; 3K39 A; 1L7H A; 3K36 A; 4GDJ A; 4XIL A; 1Z4Z A; 1MS4 A; 6NN9 A; 2DG0 A; 3H6J A; 2IAX A; 4FPL A; 3K38 A; 1N1T A; 2W8B A; 3U0S A; 2XZK A; 4JML A; 1IVB A; 3AMR A; 4K3Y A; 3PJQ A; 2YA8 A; 4N1B A; 4ZGC A; 5D9D A; 4XJZ A; 1INF A; 1NMC A; 2HTW A; 2CML A; 1W20 A; 2P4O A; 5FNQ A; 2VVZ A; 1L7F A; 3DR2 A; 1CRZ A; 2GVX A; 4B7J A; 5GTQ A; 1W0O A; 3E5Z A; 1INV A; 1MZ6 A; 3W09 A; 1E1A A; 4M4V A; 1V3C A; 1NNB A; 2F24 A; 4BBW A; 2QWJ A; 1NCB N; 2IAU A; 4XJ9 A; 3CYE A; 4GZS A; 1B9T A; 3SRG A; 2V91 A; 4KS5 A; 1DIM A; 1NSB A; 2C4A A; 5HUN A; 1BJI A; 3TI6 A; 1F8E A; 3V65 B; 4UF7 A; 2FLU X; 1INW A; 3A9H A; 4NC5 A; 1V0F A; 1IUC A; 4XIK A; 1W8O A; 1N1V A; 4HZV A; 1MS5 A; 4XJW A; 4D52 C; 3A9G A; 4H53 A; 3WDZ A; 1ING A; 1K32 A; 3ADE A; 1USX A; 1S0I A; 1MS1 A; 4MJU A; 4FOY A; 4IFL X; 1ZI0 A; 4O5T A; 4CPL A; 2YDP A; 1VCJ A; 4XJR A; 4R40 A; 4XE9 A; 4AGT A; 4K1I A; 4I00 A; 1NN2 A; 5EO7 A; 2BZD A; 2VSK A; 5GX1 A; 2GHS A; 3K37 A; 4FZH A; 4ZY3 A; 4GZP A; 2VSM A; 3VNH A; 2QWA A; 4FQ4 A; 4GN8 A; 2F11 A; 1U6D X; 1Z4Y A; 2HU0 A; 4HHO A; 3DAS A; 2F12 A; 1IVD A; 3CL0 A; 2POO A; 2HTV A; 5B2C A; 2W5N A; 2QWD A; 3GVJ A; 4B7Q A; 2F28 A; 2AGS A; 3ZGD A; 2AH2 A; 4YW5 A; 1PJX A; 2ZZK A; 4FOV A; 3H73 A; 2VW2 A; 3T1E A; 2W38 A; 1W8N A; 4FVK A; 3TC9 A; 4IN4 A; 2ZWA A; 1SNT A; 3ALX A; 4L7D A; 1B9S A; 3OPZ A; 3SRE A; 3II7 A; 2F29 A; 1RWI A; 2AEQ A; 4D8S A; 1NMA N; 2VAQ A; 4M3M A; 2IAW A; 2XZI A; 2ZW9 A; 1USR A; 1NCD N; 4CPO A; 2GVU A; 2DYH A; 4HZW A; 2BF6 A; 4HZX A; 4FPE A; 4QN5 A; 4X4A A; 4C1Y B; 1OFZ A; 4IMB A; 4D4U A; 2AEP A; 1A14 N; 2IAT A; 2ZB6 A; 4HIZ A; 1MS8 A; 2VW1 A; 4KS2 A; 4K1J A; 5D9C A; 1S1D A; 4MWX A; 1POO A; 4X6K A; 2Z32 A; 4ZLR A; 4DG6 A; 2QWG A; 4IFN X; 4MWR A; 1KIT A; 4CPZ A; 1INY A; 4SLI A; 3TIB A; 3H71 A; 2VK6 A; 4HZY A; 3BYC A; 3TIA A; 4XJU A; 2IAR A; 2F27 A; 2IAO A; 2SIL A; 7NN9 A; 3D11 A; 4C1Y A; 4QN6 A; 4D52 B; 1N6D A; 1RWL A; 3HRP A; 2YA5 A; 3SOV A; 4GB1 A; 1A4Q A; 2YA7 A; 4MJV A; 3WWA A; 2YDT A; 4J9T A; 3GVK A; 2QWF A; 1XOG A; 4XMA A; 2W20 A; 3K3A A; 2HTQ A; 3L6V A; 1V3E A; 4Q6K A; 4WA4 A; 1IJQ A; 5GX5 A; 2HU4 A; 4NCS A; 3H72 A; 3FW0 A; 5CGJ A; 2YA4 A; 5M1Z A; 1NSC A; 4JF7 A; 3FVZ A; 2SIM A; 1Q7F A; 2DG1 A; 4HW6 A; 1MR5 A; 1V2I A; 3ZGC A; 1IVF A; 5JYY A; 4D52 A; 1IVG A; 1V0Z A; 4GNA A; 4KS3 A; 2HTY A; 1INX A; 4FPC A; 2X9M A; 1E8U A; 2IAS A; 2F25 A; 4CH9 A; 1N1S A; 3NN9 A; 4GZW A; 4HZZ A; 4B7N A; 3SOQ A; 4WA5 A; 4XHX A; 1Z50 A; 2H2N A; 1QBI A; 3WW9 A; 2HT8 A; 4FPJ A; 2F10 A; 1CVM A; 1INH A; 2VW0 A; 5B2D A; 2QWI A; 1W21 A; 3NSS A; 1W1X A; 3LI3 A; 1EUS A; 2G8S A; 2JKB A; 1A4G A; 2HTR A; 2VK5 A; 2QWB A; 1VCU A; 3O9K A; 3TI4 A; 1Z4X A; 1S18 A; 2SLI A; 1EUT A; 3S8Z A; 3UC1 A; 2FPB A; 3B69 A; 2HQS A; 4GEZ A; 1NNC A; 3V64 C; 1MWE A; 3A71 A; 1E8V A; 2RKC A; 1IVC A; 1X2R A; 4MWL A; 1N1Y A; 2F0Z A; 3LI5 A; 5FWW A; 2HT7 A; 4GZX A; 5FNR A; 4FP3 A; 4QN7 A; 4CSD A; 4G3N A; 1QLG A; 4B7R A; 1H6L A; 4AGI A; 4IFJ A; 1NCC N; 2DSO A; 4GN7 A; 1L7G A; 1Z4V A; 2A75 A; 4FP2 A; 3TIC A; 4YZ2 A; 4KS4 A; 3VNG A; 3JU4 A; 3SLI A; 1NSD A; 4CPM A; 1Z4W A; 4M4N A; 1SLI A; 4DGR A; 4MWQ A; #chains in the Genus database with same CATH homology 4CHB A; 4ASC A; 5FNR A; 4ZY3 A; 2FLU X; 5FNT A; 5FZN A; 1ZGK A; 2XN4 A; 3VNH A; 3WN7 A; 4N1B A; 4ZGC A; 4IN4 A; 1X2J A; 2WOZ A; 2ZWA A; 5FZJ A; 2VPJ A; 1U6D X; 3ZGC A; 5FNU A; 3WDZ A; 2Z32 A; 4L7D A; 4YY8 A; 4IFJ A; 4IFN X; 3ADE A; 3II7 A; 4IQK A; 5FNS A; 4IFL X; 5FNQ A; 2ZW9 A; 5F72 C; 4L7B A; 4L7C A; 3ZGD A; 3VNG A; 4XMB A; 2DYH A; 4CH9 A; 2ZZK A; 1X2R A; 5CGJ A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
