4N1ZF

Crystal structure of human farnesyl diphosphate synthase in complex with bph-1222
Total Genus 127
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
340
structure length
333
Chain Sequence
VYAQEKQDFVQHFSQIVRVLTHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycin.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Farnesyl pyrophosphate synthase
total genus 127
structure length 333
sequence length 340
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2013-10-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4n1zF00
1N21A 3G4FA 4K10A 4LUUA 3LG5A 3MAVA 4KUXA 3WSBA 1V4EA 4GP2A 4H5EF 4NG6A 3NRIA 3WCGA 3KBKA 4GP1A 3LVSA 2E93A 5IM1A 4FP4A 3N5HF 4HD1A 1VG3A 1UBVA 3G4DA 2H8OA 2F9KF 5EASA 5B0IA 4LTZA 4WK5A 3P5PA 4OMHA 4F62A 4MC0A 4RYPA 5A0IA 4LIXA 5B02A 2Z4YA 3M01A 3N3DA 1YHMA 1YYTA 3EGTA 5ER8A 1V4IA 3LJIA 3VJBA 4P0VA 5C05A 3WEFA 1N24A 3LMDA 5IK0A 4PVXF 5DJPF 3P41A 4GA3A 2P1CA 4RXDA 5IKHA 4XQSF 2ZCOA 2EWGA 3EZ3A 3LDWA 3VJ9A 4NKFA 3PKOA 2E8WA 2J1PA 4KWDA 5A0KA 4E1EA 5IL3A 1YYUA 5EAUA 3M00A 2Q9YA 2FORA 3N5JF 2F8CF 4LA5A 2ZCSA 5DW7A 3WCLA 2VF6A 5EROA 3WCAA 3KRCB 3PYAA 5CG6A 3AQ0A 4NFJF 3N45F 4KFAA 3KRPB 5DIQF 4NKEA 3PYBA 3WE9A 3SDVA 4RXEA 1JFGA 1YJ4A 4JXYA 2OA6A 3PH7A 5B0JA 3PDEA 1HM7A 1HXGA 5HN7A 1WL1A 3KRFA 2AETA 4MC8A 5A0JA 2F7MF 3LSNA 2O1OA 2Q9ZA 5ILKA 2ZEVA 1N22A 1KIZA 5ILZA 5DHKA 4KVWA 3LLWA 1RQJA 4KVIA 5B0MA 4LFEA 1YV5A 5IK6A 3ID0A 4LTVA 2AZLA 4E9UA 1VG2A 3WEKA 2E8VA 3TFPA 5JA0F 3S9VA 1V4JA 2ZY1A 1HM4A 5IMNA 3CKEA 4LZ0A 3M9UA 1YQ7A 3WCDA 1HX9A 3AQCB 2E90A 3DYFA 3ASXA 4KQ5A 3DYGA 4LA6A 1N20A 4LPHF 5AELA 3WCMA 4RXCA 2AELA 2OPNA 3B7LA 3LEEA 3Q2QA 3QKCA 5ERNA 3RYEA 3WEGA 5ILJA 5E8KA 1JFAA 4KK2A 4NFKF 2FTZA 2PS7A 3NPKA 2Q80A 3NPRA 2I19A 4H5DF 4PVYF 4P0WA 3V66A 3VJEA 4EA2A 2E92A 1UBWA 2PS6A 4JZXA 5AFXA 5IVGA 3N49F 3M02A 3LGKA 4QXSF 5ILYA 3P5RA 3KRCA 2ZEUA 3P8RA 1N1BA 2AZKA 3ZMBA 5ERMA 4RXAA 4NFIF 1DGPA 3KRPA 5ILDA 4JVJF 1VG7A 3N3LF 1YYRA 3ICKA 5E8LA 3LZ9A 3DYHA 3VJCA 4RNQA 3CC9A 1PS1A 2Z7IA 1N23A 4XQRF 5HN8A 3WJNA 4P0XA 5ILHA 2F8ZF 2QISA 5H9DA 1VG6A 5DHIA 4DHDA 4LPGF 4EA0A 1HXAA 3ZCDA 4LFVF 3VJ8A 4GAXA 2E8TA 1V4KA 2ONGA 2PS8A 3WEHA 4F6VA 2F92F 3VJDA 5CG5A 3QQVA 1YYQA 1WMWA 3OABB 3BNYA 4LXWA 3RBMA 2E95A 1WL0A 3SAEA 3Q30A 3RMGA 4DEMF 1RTRA 5AHUB 5IMIA 5DGMF 3WEIA 5DZ2A 2AEKA 4LZCA 5B00A 4DXJA 4EA1A 3V1XA 4H5CF 3WJKA 3WEJA 4OMGA 2E94A 4FJQA 3WCEA 5JV1F 3LOMA 4OKZA 2Z52A 4JXNA 3OACB 3M0GA 3AQBB 3TFVA 2OPMA 5B0KA 3LGZB 4LOBA 5E8HA 4LLSA 3W7FA 3WCIA 3BNXA 3ICMA 1WL2A 3N1WF 2ZCQA 4LZ3A 3WSAA 1UBYA 4KQSA 1KIYA 3ACWA 1HXCA 3KRFB 5HNAA 3OYRA 3ADZA 2E8UA 3TFNA 3V1VA 3KRAB 1WL3A 3NF2A 3ACYA 4KVDA 3UCAA 5B03A 3WCBA 5DJRF 5IMPA 4MC3A 3AE0A 4F6XA 1EZFA 4KKMA 5DGSF 5I1UA 3RYWA 3ICZA 4E9ZA 2Z78A 3S4JA 3TC1A 1FPSA 1WKZA 3IPIA 5IK9A 4UMJA 3EFQA 5EATA 2ONHA 3ZMCA 3N46F 4KQUA 1ZW5A 3KROB 2DH4A 5IL8A 4DZWA 5DGNF 3SDTA 4JZBA 3N6KF 3ZOUA 3MZVA 3SDRA 3SDQA 3ICNA 3N1VF 2RAHA 5DJVF 4DWGA 2PS5A 3OABA 2Z4WA 4DI5A 2Z7HA 2Z50A 3WCHA 3CP6A 3WCCA 2ZCRA 5JV2F 1RQIA 3VJAA 4N1ZF 4LFGA 3P8LA 5ILIA 2Z4XA 2E91A 4NUAA 3N0GA 5KSXF 5B0LA 5JUZF 4L2XF 4JYXA 3WCJA 1YYSA 5IKAA 3LK5A 3OACA 4KPJA 2Z4ZA 3Q1OA 4Q23A 2OGDA 4QPFA 1YHLA 2F94F 2J1OA 1DI1A 2Q58A 2Z4VA 3ACXA 3N0FA 2PS4A 4XQTF 1UBXA 3WCFA 1WY0A 4KPDA 4LLTA 1V4HA 3TS7A 4OGUA 2E8XA 2F89F 3WJOA 4N9UA 2E4OA 4KVYA 3ZL6A 3KRAA 1N1ZA 5B01A 2AZJA 5JV0F 1VG4A 3SDUA 4ZQ8A 4OKMA 3WC9A 4DWBA 3IBAA 3Q2ZA 3KB9A 5AYPA 5IN8A 3APZA 2J5CA 5HN9A 1YHKA 3KROA
chains in the Genus database with same CATH superfamily
1N21A 3G4FA 4K10A 4LUUA 3LG5A 3MAVA 4KUXA 3WSBA 1V4EA 4GP2A 4H5EF 4NG6A 3NRIA 3WCGA 3KBKA 4GP1A 3LVSA 2E93A 5IM1A 4FP4A 3N5HF 4HD1A 1VG3A 1UBVA 3G4DA 2H8OA 2F9KF 5EASA 5B0IA 4LTZA 4WK5A 3P5PA 4OMHA 4F62A 4MC0A 4RYPA 5A0IA 4LIXA 5B02A 2Z4YA 3M01A 3N3DA 1YHMA 1YYTA 3EGTA 5ER8A 1V4IA 3LJIA 3VJBA 4P0VA 5C05A 3WEFA 1N24A 3LMDA 5IK0A 4PVXF 5DJPF 3P41A 4GA3A 2P1CA 4RXDA 5IKHA 4XQSF 2ZCOA 2EWGA 3EZ3A 3LDWA 3VJ9A 4NKFA 3PKOA 2E8WA 2J1PA 4KWDA 5A0KA 4E1EA 5IL3A 1YYUA 5EAUA 3M00A 2Q9YA 2FORA 3N5JF 2F8CF 4LA5A 2ZCSA 5DW7A 3WCLA 2VF6A 5EROA 3WCAA 3KRCB 3PYAA 5CG6A 3AQ0A 4NFJF 3N45F 4KFAA 3KRPB 5DIQF 4NKEA 3PYBA 3WE9A 3SDVA 4RXEA 1JFGA 1YJ4A 4JXYA 2OA6A 3PH7A 5B0JA 3PDEA 1HM7A 1HXGA 5HN7A 1WL1A 3KRFA 2AETA 4MC8A 5A0JA 2F7MF 3LSNA 2O1OA 2Q9ZA 5ILKA 2ZEVA 1N22A 1KIZA 5ILZA 5DHKA 4KVWA 3LLWA 1RQJA 4KVIA 5B0MA 4LFEA 1YV5A 5IK6A 3ID0A 4LTVA 2AZLA 4E9UA 1VG2A 3WEKA 2E8VA 3TFPA 5JA0F 3S9VA 1V4JA 2ZY1A 1HM4A 5IMNA 3CKEA 4LZ0A 3M9UA 1YQ7A 3WCDA 1HX9A 3AQCB 2E90A 3DYFA 3ASXA 4KQ5A 3DYGA 4LA6A 1N20A 4LPHF 5AELA 3WCMA 4RXCA 2AELA 2OPNA 3B7LA 3LEEA 3Q2QA 3QKCA 5ERNA 3RYEA 3WEGA 5ILJA 5E8KA 1JFAA 4KK2A 4NFKF 2FTZA 2PS7A 3NPKA 2Q80A 3NPRA 2I19A 4H5DF 4PVYF 4P0WA 3V66A 3VJEA 4EA2A 2E92A 1UBWA 2PS6A 4JZXA 5AFXA 5IVGA 3N49F 3M02A 3LGKA 4QXSF 5ILYA 3P5RA 3KRCA 2ZEUA 3P8RA 1N1BA 2AZKA 3ZMBA 5ERMA 4RXAA 4NFIF 1DGPA 3KRPA 5ILDA 4JVJF 1VG7A 3N3LF 1YYRA 3ICKA 5E8LA 3LZ9A 3DYHA 3VJCA 4RNQA 3CC9A 1PS1A 2Z7IA 1N23A 4XQRF 5HN8A 3WJNA 4P0XA 5ILHA 2F8ZF 2QISA 5H9DA 1VG6A 5DHIA 4DHDA 4LPGF 4EA0A 1HXAA 3ZCDA 4LFVF 3VJ8A 4GAXA 2E8TA 1V4KA 2ONGA 2PS8A 3WEHA 4F6VA 2F92F 3VJDA 5CG5A 3QQVA 1YYQA 1WMWA 3OABB 3BNYA 4LXWA 3RBMA 2E95A 1WL0A 3SAEA 3Q30A 3RMGA 4DEMF 1RTRA 5AHUB 5IMIA 5DGMF 3WEIA 5DZ2A 2AEKA 4LZCA 5B00A 4DXJA 4EA1A 3V1XA 4H5CF 3WJKA 3WEJA 4OMGA 2E94A 4FJQA 3WCEA 5JV1F 3LOMA 4OKZA 2Z52A 4JXNA 3OACB 3M0GA 3AQBB 3TFVA 2OPMA 5B0KA 3LGZB 4LOBA 5E8HA 4LLSA 3W7FA 3WCIA 3BNXA 3ICMA 1WL2A 3N1WF 2ZCQA 4LZ3A 3WSAA 1UBYA 4KQSA 1KIYA 3ACWA 1HXCA 3KRFB 5HNAA 3OYRA 3ADZA 2E8UA 3TFNA 3V1VA 3KRAB 1WL3A 3NF2A 3ACYA 4KVDA 3UCAA 5B03A 3WCBA 5DJRF 5IMPA 4MC3A 3AE0A 4F6XA 1EZFA 4KKMA 5DGSF 5I1UA 3RYWA 3ICZA 4E9ZA 2Z78A 3S4JA 3TC1A 1FPSA 1WKZA 3IPIA 5IK9A 4UMJA 3EFQA 5EATA 2ONHA 3ZMCA 3N46F 4KQUA 1ZW5A 3KROB 2DH4A 5IL8A 4DZWA 5DGNF 3SDTA 4JZBA 3N6KF 3ZOUA 3MZVA 3SDRA 3SDQA 3ICNA 3N1VF 2RAHA 5DJVF 4DWGA 2PS5A 3OABA 2Z4WA 4DI5A 2Z7HA 2Z50A 3WCHA 3CP6A 3WCCA 2ZCRA 5JV2F 1RQIA 3VJAA 4N1ZF 4LFGA 3P8LA 5ILIA 2Z4XA 2E91A 4NUAA 3N0GA 5KSXF 5B0LA 5JUZF 4L2XF 4JYXA 3WCJA 1YYSA 5IKAA 3LK5A 3OACA 4KPJA 2Z4ZA 3Q1OA 4Q23A 2OGDA 4QPFA 1YHLA 2F94F 2J1OA 1DI1A 2Q58A 2Z4VA 3ACXA 3N0FA 2PS4A 4XQTF 1UBXA 3WCFA 1WY0A 4KPDA 4LLTA 1V4HA 3TS7A 4OGUA 2E8XA 2F89F 3WJOA 4N9UA 2E4OA 4KVYA 3ZL6A 3KRAA 1N1ZA 5B01A 2AZJA 5JV0F 1VG4A 3SDUA 4ZQ8A 4OKMA 3WC9A 4DWBA 3IBAA 3Q2ZA 3KB9A 5AYPA 5IN8A 3APZA 2J5CA 5HN9A 1YHKA 3KROA
chains in the Genus database with same CATH topology
1N21A 3G4FA 4K10A 4LUUA 3LG5A 3MAVA 4KUXA 3WSBA 1V4EA 4GP2A 4H5EF 4NG6A 3NRIA 3WCGA 3KBKA 4GP1A 3LVSA 2E93A 5IM1A 4FP4A 3N5HF 4HD1A 1VG3A 1UBVA 3G4DA 2H8OA 2F9KF 5EASA 5B0IA 4LTZA 4WK5A 3P5PA 4OMHA 4F62A 4MC0A 4RYPA 5A0IA 4LIXA 5B02A 2Z4YA 3M01A 3N3DA 1YHMA 1YYTA 3EGTA 5ER8A 1V4IA 3LJIA 3VJBA 4P0VA 5C05A 3WEFA 1N24A 3LMDA 5IK0A 4PVXF 5DJPF 3P41A 4GA3A 2P1CA 4RXDA 5IKHA 4XQSF 2ZCOA 2EWGA 3EZ3A 3LDWA 3VJ9A 4NKFA 3PKOA 2E8WA 2J1PA 4KWDA 5A0KA 4E1EA 5IL3A 1YYUA 5EAUA 3M00A 2Q9YA 2FORA 3N5JF 2F8CF 4LA5A 2ZCSA 5DW7A 3WCLA 2VF6A 5EROA 3WCAA 3KRCB 3PYAA 5CG6A 3AQ0A 4NFJF 3N45F 4KFAA 3KRPB 5DIQF 4NKEA 3PYBA 3WE9A 3SDVA 4RXEA 1JFGA 1YJ4A 4JXYA 2OA6A 3PH7A 5B0JA 3PDEA 1HM7A 1HXGA 5HN7A 1WL1A 3KRFA 2AETA 4MC8A 5A0JA 2F7MF 3LSNA 2O1OA 2Q9ZA 5ILKA 2ZEVA 1N22A 1KIZA 5ILZA 5DHKA 4KVWA 3LLWA 1RQJA 4KVIA 5B0MA 4LFEA 1YV5A 5IK6A 3ID0A 4LTVA 2AZLA 4E9UA 1VG2A 3WEKA 2E8VA 3TFPA 5JA0F 3S9VA 1V4JA 2ZY1A 1HM4A 5IMNA 3CKEA 4LZ0A 3M9UA 1YQ7A 3WCDA 1HX9A 3AQCB 2E90A 3DYFA 3ASXA 4KQ5A 3DYGA 4LA6A 1N20A 4LPHF 5AELA 3WCMA 4RXCA 2AELA 2OPNA 3B7LA 3LEEA 3Q2QA 3QKCA 5ERNA 3RYEA 3WEGA 5ILJA 5E8KA 1JFAA 4KK2A 4NFKF 2FTZA 2PS7A 3NPKA 2Q80A 3NPRA 2I19A 4H5DF 4PVYF 4P0WA 3V66A 3VJEA 4EA2A 2E92A 1UBWA 2PS6A 4JZXA 5AFXA 5IVGA 3N49F 3M02A 3LGKA 4QXSF 5ILYA 3P5RA 3KRCA 2ZEUA 3P8RA 1N1BA 2AZKA 3ZMBA 5ERMA 4RXAA 4NFIF 1DGPA 3KRPA 5ILDA 4JVJF 1VG7A 3N3LF 1YYRA 3ICKA 5E8LA 3LZ9A 3DYHA 3VJCA 4RNQA 3CC9A 1PS1A 2Z7IA 1N23A 4XQRF 5HN8A 3WJNA 4P0XA 5ILHA 2F8ZF 2QISA 5H9DA 1VG6A 5DHIA 4DHDA 4LPGF 4EA0A 1HXAA 3ZCDA 4LFVF 3VJ8A 4GAXA 2E8TA 1V4KA 2ONGA 2PS8A 3WEHA 4F6VA 2F92F 3VJDA 5CG5A 3QQVA 1YYQA 1WMWA 3OABB 3BNYA 4LXWA 3RBMA 2E95A 1WL0A 3SAEA 3Q30A 3RMGA 4DEMF 1RTRA 5AHUB 5IMIA 5DGMF 3WEIA 5DZ2A 2AEKA 4LZCA 5B00A 4DXJA 4EA1A 3V1XA 4H5CF 3WJKA 3WEJA 4OMGA 2E94A 4FJQA 3WCEA 5JV1F 3LOMA 4OKZA 2Z52A 4JXNA 3OACB 3M0GA 3AQBB 3TFVA 2OPMA 5B0KA 3LGZB 4LOBA 5E8HA 4LLSA 3W7FA 3WCIA 3BNXA 3ICMA 1WL2A 3N1WF 2ZCQA 4LZ3A 3WSAA 1UBYA 4KQSA 1KIYA 3ACWA 1HXCA 3KRFB 5HNAA 3OYRA 3ADZA 2E8UA 3TFNA 3V1VA 3KRAB 1WL3A 3NF2A 3ACYA 4KVDA 3UCAA 5B03A 3WCBA 5DJRF 5IMPA 4MC3A 3AE0A 4F6XA 1EZFA 4KKMA 5DGSF 5I1UA 3RYWA 3ICZA 4E9ZA 2Z78A 3S4JA 3TC1A 1FPSA 1WKZA 3IPIA 5IK9A 4UMJA 3EFQA 5EATA 2ONHA 3ZMCA 3N46F 4KQUA 1ZW5A 3KROB 2DH4A 5IL8A 4DZWA 5DGNF 3SDTA 4JZBA 3N6KF 3ZOUA 3MZVA 3SDRA 3SDQA 3ICNA 3N1VF 2RAHA 5DJVF 4DWGA 2PS5A 3OABA 2Z4WA 4DI5A 2Z7HA 2Z50A 3WCHA 3CP6A 3WCCA 2ZCRA 5JV2F 1RQIA 3VJAA 4N1ZF 4LFGA 3P8LA 5ILIA 2Z4XA 2E91A 4NUAA 3N0GA 5KSXF 5B0LA 5JUZF 4L2XF 4JYXA 3WCJA 1YYSA 5IKAA 3LK5A 3OACA 4KPJA 2Z4ZA 3Q1OA 4Q23A 2OGDA 4QPFA 1YHLA 2F94F 2J1OA 1DI1A 2Q58A 2Z4VA 3ACXA 3N0FA 2PS4A 4XQTF 1UBXA 3WCFA 1WY0A 4KPDA 4LLTA 1V4HA 3TS7A 4OGUA 2E8XA 2F89F 3WJOA 4N9UA 2E4OA 4KVYA 3ZL6A 3KRAA 1N1ZA 5B01A 2AZJA 5JV0F 1VG4A 3SDUA 4ZQ8A 4OKMA 3WC9A 4DWBA 3IBAA 3Q2ZA 3KB9A 5AYPA 5IN8A 3APZA 2J5CA 5HN9A 1YHKA 3KROA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N21 A;  3G4F A;  4K10 A;  4LUU A;  3LG5 A;  3MAV A;  4KUX A;  3WSB A;  1V4E A;  4GP2 A;  4H5E F;  4NG6 A;  3NRI A;  3WCG A;  3KBK A;  4GP1 A;  3LVS A;  2E93 A;  5IM1 A;  4FP4 A;  3N5H F;  4HD1 A;  1VG3 A;  1UBV A;  3G4D A;  2H8O A;  2F9K F;  5EAS A;  5B0I A;  4LTZ A;  4WK5 A;  3P5P A;  4OMH A;  4F62 A;  4MC0 A;  4RYP A;  5A0I A;  4LIX A;  5B02 A;  2Z4Y A;  3M01 A;  3N3D A;  1YHM A;  1YYT A;  3EGT A;  5ER8 A;  1V4I A;  3LJI A;  3VJB A;  4P0V A;  5C05 A;  3WEF A;  1N24 A;  3LMD A;  5IK0 A;  4PVX F;  5DJP F;  3P41 A;  4GA3 A;  2P1C A;  4RXD A;  5IKH A;  4XQS F;  2ZCO A;  2EWG A;  3EZ3 A;  3LDW A;  3VJ9 A;  4NKF A;  3PKO A;  2E8W A;  2J1P A;  4KWD A;  5A0K A;  4E1E A;  5IL3 A;  1YYU A;  5EAU A;  3M00 A;  2Q9Y A;  2FOR A;  3N5J F;  2F8C F;  4LA5 A;  2ZCS A;  5DW7 A;  3WCL A;  2VF6 A;  5ERO A;  3WCA A;  3KRC B;  3PYA A;  5CG6 A;  3AQ0 A;  4NFJ F;  3N45 F;  4KFA A;  3KRP B;  5DIQ F;  4NKE A;  3PYB A;  3WE9 A;  3SDV A;  4RXE A;  1JFG A;  1YJ4 A;  4JXY A;  2OA6 A;  3PH7 A;  5B0J A;  3PDE A;  1HM7 A;  1HXG A;  5HN7 A;  1WL1 A;  3KRF A;  2AET A;  4MC8 A;  5A0J A;  2F7M F;  3LSN A;  2O1O A;  2Q9Z A;  5ILK A;  2ZEV A;  1N22 A;  1KIZ A;  5ILZ A;  5DHK A;  4KVW A;  3LLW A;  1RQJ A;  4KVI A;  5B0M A;  4LFE A;  1YV5 A;  5IK6 A;  3ID0 A;  4LTV A;  2AZL A;  4E9U A;  1VG2 A;  3WEK A;  2E8V A;  3TFP A;  5JA0 F;  3S9V A;  1V4J A;  2ZY1 A;  1HM4 A;  5IMN A;  3CKE A;  4LZ0 A;  3M9U A;  1YQ7 A;  3WCD A;  1HX9 A;  3AQC B;  2E90 A;  3DYF A;  3ASX A;  4KQ5 A;  3DYG A;  4LA6 A;  1N20 A;  4LPH F;  5AEL A;  3WCM A;  4RXC A;  2AEL A;  2OPN A;  3B7L A;  3LEE A;  3Q2Q A;  3QKC A;  5ERN A;  3RYE A;  3WEG A;  5ILJ A;  5E8K A;  1JFA A;  4KK2 A;  4NFK F;  2FTZ A;  2PS7 A;  3NPK A;  2Q80 A;  3NPR A;  2I19 A;  4H5D F;  4PVY F;  4P0W A;  3V66 A;  3VJE A;  4EA2 A;  2E92 A;  1UBW A;  2PS6 A;  4JZX A;  5AFX A;  5IVG A;  3N49 F;  3M02 A;  3LGK A;  4QXS F;  5ILY A;  3P5R A;  3KRC A;  2ZEU A;  3P8R A;  1N1B A;  2AZK A;  3ZMB A;  5ERM A;  4RXA A;  4NFI F;  1DGP A;  3KRP A;  5ILD A;  4JVJ F;  1VG7 A;  3N3L F;  1YYR A;  3ICK A;  5E8L A;  3LZ9 A;  3DYH A;  3VJC A;  4RNQ A;  3CC9 A;  1PS1 A;  2Z7I A;  1N23 A;  4XQR F;  5HN8 A;  3WJN A;  4P0X A;  5ILH A;  2F8Z F;  2QIS A;  5H9D A;  1VG6 A;  5DHI A;  4DHD A;  4LPG F;  4EA0 A;  1HXA A;  3ZCD A;  4LFV F;  3VJ8 A;  4GAX A;  2E8T A;  1V4K A;  2ONG A;  2PS8 A;  3WEH A;  4F6V A;  2F92 F;  3VJD A;  5CG5 A;  3QQV A;  1YYQ A;  1WMW A;  3OAB B;  3BNY A;  4LXW A;  3RBM A;  2E95 A;  1WL0 A;  3SAE A;  3Q30 A;  3RMG A;  4DEM F;  1RTR A;  5AHU B;  5IMI A;  5DGM F;  3WEI A;  5DZ2 A;  2AEK A;  4LZC A;  5B00 A;  4DXJ A;  4EA1 A;  3V1X A;  4H5C F;  3WJK A;  3WEJ A;  4OMG A;  2E94 A;  4FJQ A;  3WCE A;  5JV1 F;  3LOM A;  4OKZ A;  2Z52 A;  4JXN A;  3OAC B;  3M0G A;  3AQB B;  3TFV A;  2OPM A;  5B0K A;  3LGZ B;  4LOB A;  5E8H A;  4LLS A;  3W7F A;  3WCI A;  3BNX A;  3ICM A;  1WL2 A;  3N1W F;  2ZCQ A;  4LZ3 A;  3WSA A;  1UBY A;  4KQS A;  1KIY A;  3ACW A;  1HXC A;  3KRF B;  5HNA A;  3OYR A;  3ADZ A;  2E8U A;  3TFN A;  3V1V A;  3KRA B;  1WL3 A;  3NF2 A;  3ACY A;  4KVD A;  3UCA A;  5B03 A;  3WCB A;  5DJR F;  5IMP A;  4MC3 A;  3AE0 A;  4F6X A;  1EZF A;  4KKM A;  5DGS F;  5I1U A;  3RYW A;  3ICZ A;  4E9Z A;  2Z78 A;  3S4J A;  3TC1 A;  1FPS A;  1WKZ A;  3IPI A;  5IK9 A;  4UMJ A;  3EFQ A;  5EAT A;  2ONH A;  3ZMC A;  3N46 F;  4KQU A;  1ZW5 A;  3KRO B;  2DH4 A;  5IL8 A;  4DZW A;  5DGN F;  3SDT A;  4JZB A;  3N6K F;  3ZOU A;  3MZV A;  3SDR A;  3SDQ A;  3ICN A;  3N1V F;  2RAH A;  5DJV F;  4DWG A;  2PS5 A;  3OAB A;  2Z4W A;  4DI5 A;  2Z7H A;  2Z50 A;  3WCH A;  3CP6 A;  3WCC A;  2ZCR A;  5JV2 F;  1RQI A;  3VJA A;  4N1Z F;  4LFG A;  3P8L A;  5ILI A;  2Z4X A;  2E91 A;  4NUA A;  3N0G A;  5KSX F;  5B0L A;  5JUZ F;  4L2X F;  4JYX A;  3WCJ A;  1YYS A;  5IKA A;  3LK5 A;  3OAC A;  4KPJ A;  2Z4Z A;  3Q1O A;  4Q23 A;  2OGD A;  4QPF A;  1YHL A;  2F94 F;  2J1O A;  1DI1 A;  2Q58 A;  2Z4V A;  3ACX A;  3N0F A;  2PS4 A;  4XQT F;  1UBX A;  3WCF A;  1WY0 A;  4KPD A;  4LLT A;  1V4H A;  3TS7 A;  4OGU A;  2E8X A;  2F89 F;  3WJO A;  4N9U A;  2E4O A;  4KVY A;  3ZL6 A;  3KRA A;  1N1Z A;  5B01 A;  2AZJ A;  5JV0 F;  1VG4 A;  3SDU A;  4ZQ8 A;  4OKM A;  3WC9 A;  4DWB A;  3IBA A;  3Q2Z A;  3KB9 A;  5AYP A;  5IN8 A;  3APZ A;  2J5C A;  5HN9 A;  1YHK A;  3KRO A; 
#chains in the Genus database with same CATH topology
 1N21 A;  3G4F A;  4K10 A;  4LUU A;  3LG5 A;  3MAV A;  4KUX A;  3WSB A;  1V4E A;  4GP2 A;  4H5E F;  4NG6 A;  3NRI A;  3WCG A;  3KBK A;  4GP1 A;  3LVS A;  2E93 A;  5IM1 A;  4FP4 A;  3N5H F;  4HD1 A;  1VG3 A;  1UBV A;  3G4D A;  2H8O A;  2F9K F;  5EAS A;  5B0I A;  4LTZ A;  4WK5 A;  3P5P A;  4OMH A;  4F62 A;  4MC0 A;  4RYP A;  5A0I A;  4LIX A;  5B02 A;  2Z4Y A;  3M01 A;  3N3D A;  1YHM A;  1YYT A;  3EGT A;  5ER8 A;  1V4I A;  3LJI A;  3VJB A;  4P0V A;  5C05 A;  3WEF A;  1N24 A;  3LMD A;  5IK0 A;  4PVX F;  5DJP F;  3P41 A;  4GA3 A;  2P1C A;  4RXD A;  5IKH A;  4XQS F;  2ZCO A;  2EWG A;  3EZ3 A;  3LDW A;  3VJ9 A;  4NKF A;  3PKO A;  2E8W A;  2J1P A;  4KWD A;  5A0K A;  4E1E A;  5IL3 A;  1YYU A;  5EAU A;  3M00 A;  2Q9Y A;  2FOR A;  3N5J F;  2F8C F;  4LA5 A;  2ZCS A;  5DW7 A;  3WCL A;  2VF6 A;  5ERO A;  3WCA A;  3KRC B;  3PYA A;  5CG6 A;  3AQ0 A;  4NFJ F;  3N45 F;  4KFA A;  3KRP B;  5DIQ F;  4NKE A;  3PYB A;  3WE9 A;  3SDV A;  4RXE A;  1JFG A;  1YJ4 A;  4JXY A;  2OA6 A;  3PH7 A;  5B0J A;  3PDE A;  1HM7 A;  1HXG A;  5HN7 A;  1WL1 A;  3KRF A;  2AET A;  4MC8 A;  5A0J A;  2F7M F;  3LSN A;  2O1O A;  2Q9Z A;  5ILK A;  2ZEV A;  1N22 A;  1KIZ A;  5ILZ A;  5DHK A;  4KVW A;  3LLW A;  1RQJ A;  4KVI A;  5B0M A;  4LFE A;  1YV5 A;  5IK6 A;  3ID0 A;  4LTV A;  2AZL A;  4E9U A;  1VG2 A;  3WEK A;  2E8V A;  3TFP A;  5JA0 F;  3S9V A;  1V4J A;  2ZY1 A;  1HM4 A;  5IMN A;  3CKE A;  4LZ0 A;  3M9U A;  1YQ7 A;  3WCD A;  1HX9 A;  3AQC B;  2E90 A;  3DYF A;  3ASX A;  4KQ5 A;  3DYG A;  4LA6 A;  1N20 A;  4LPH F;  5AEL A;  3WCM A;  4RXC A;  2AEL A;  2OPN A;  3B7L A;  3LEE A;  3Q2Q A;  3QKC A;  5ERN A;  3RYE A;  3WEG A;  5ILJ A;  5E8K A;  1JFA A;  4KK2 A;  4NFK F;  2FTZ A;  2PS7 A;  3NPK A;  2Q80 A;  3NPR A;  2I19 A;  4H5D F;  4PVY F;  4P0W A;  3V66 A;  3VJE A;  4EA2 A;  2E92 A;  1UBW A;  2PS6 A;  4JZX A;  5AFX A;  5IVG A;  3N49 F;  3M02 A;  3LGK A;  4QXS F;  5ILY A;  3P5R A;  3KRC A;  2ZEU A;  3P8R A;  1N1B A;  2AZK A;  3ZMB A;  5ERM A;  4RXA A;  4NFI F;  1DGP A;  3KRP A;  5ILD A;  4JVJ F;  1VG7 A;  3N3L F;  1YYR A;  3ICK A;  5E8L A;  3LZ9 A;  3DYH A;  3VJC A;  4RNQ A;  3CC9 A;  1PS1 A;  2Z7I A;  1N23 A;  4XQR F;  5HN8 A;  3WJN A;  4P0X A;  5ILH A;  2F8Z F;  2QIS A;  5H9D A;  1VG6 A;  5DHI A;  4DHD A;  4LPG F;  4EA0 A;  1HXA A;  3ZCD A;  4LFV F;  3VJ8 A;  4GAX A;  2E8T A;  1V4K A;  2ONG A;  2PS8 A;  3WEH A;  4F6V A;  2F92 F;  3VJD A;  5CG5 A;  3QQV A;  1YYQ A;  1WMW A;  3OAB B;  3BNY A;  4LXW A;  3RBM A;  2E95 A;  1WL0 A;  3SAE A;  3Q30 A;  3RMG A;  4DEM F;  1RTR A;  5AHU B;  5IMI A;  5DGM F;  3WEI A;  5DZ2 A;  2AEK A;  4LZC A;  5B00 A;  4DXJ A;  4EA1 A;  3V1X A;  4H5C F;  3WJK A;  3WEJ A;  4OMG A;  2E94 A;  4FJQ A;  3WCE A;  5JV1 F;  3LOM A;  4OKZ A;  2Z52 A;  4JXN A;  3OAC B;  3M0G A;  3AQB B;  3TFV A;  2OPM A;  5B0K A;  3LGZ B;  4LOB A;  5E8H A;  4LLS A;  3W7F A;  3WCI A;  3BNX A;  3ICM A;  1WL2 A;  3N1W F;  2ZCQ A;  4LZ3 A;  3WSA A;  1UBY A;  4KQS A;  1KIY A;  3ACW A;  1HXC A;  3KRF B;  5HNA A;  3OYR A;  3ADZ A;  2E8U A;  3TFN A;  3V1V A;  3KRA B;  1WL3 A;  3NF2 A;  3ACY A;  4KVD A;  3UCA A;  5B03 A;  3WCB A;  5DJR F;  5IMP A;  4MC3 A;  3AE0 A;  4F6X A;  1EZF A;  4KKM A;  5DGS F;  5I1U A;  3RYW A;  3ICZ A;  4E9Z A;  2Z78 A;  3S4J A;  3TC1 A;  1FPS A;  1WKZ A;  3IPI A;  5IK9 A;  4UMJ A;  3EFQ A;  5EAT A;  2ONH A;  3ZMC A;  3N46 F;  4KQU A;  1ZW5 A;  3KRO B;  2DH4 A;  5IL8 A;  4DZW A;  5DGN F;  3SDT A;  4JZB A;  3N6K F;  3ZOU A;  3MZV A;  3SDR A;  3SDQ A;  3ICN A;  3N1V F;  2RAH A;  5DJV F;  4DWG A;  2PS5 A;  3OAB A;  2Z4W A;  4DI5 A;  2Z7H A;  2Z50 A;  3WCH A;  3CP6 A;  3WCC A;  2ZCR A;  5JV2 F;  1RQI A;  3VJA A;  4N1Z F;  4LFG A;  3P8L A;  5ILI A;  2Z4X A;  2E91 A;  4NUA A;  3N0G A;  5KSX F;  5B0L A;  5JUZ F;  4L2X F;  4JYX A;  3WCJ A;  1YYS A;  5IKA A;  3LK5 A;  3OAC A;  4KPJ A;  2Z4Z A;  3Q1O A;  4Q23 A;  2OGD A;  4QPF A;  1YHL A;  2F94 F;  2J1O A;  1DI1 A;  2Q58 A;  2Z4V A;  3ACX A;  3N0F A;  2PS4 A;  4XQT F;  1UBX A;  3WCF A;  1WY0 A;  4KPD A;  4LLT A;  1V4H A;  3TS7 A;  4OGU A;  2E8X A;  2F89 F;  3WJO A;  4N9U A;  2E4O A;  4KVY A;  3ZL6 A;  3KRA A;  1N1Z A;  5B01 A;  2AZJ A;  5JV0 F;  1VG4 A;  3SDU A;  4ZQ8 A;  4OKM A;  3WC9 A;  4DWB A;  3IBA A;  3Q2Z A;  3KB9 A;  5AYP A;  5IN8 A;  3APZ A;  2J5C A;  5HN9 A;  1YHK A;  3KRO A; 
#chains in the Genus database with same CATH homology
 1N21 A;  3G4F A;  4K10 A;  4LUU A;  3LG5 A;  3MAV A;  4KUX A;  3WSB A;  1V4E A;  4GP2 A;  4H5E F;  4NG6 A;  3NRI A;  3WCG A;  3KBK A;  4GP1 A;  3LVS A;  2E93 A;  5IM1 A;  4FP4 A;  3N5H F;  4HD1 A;  1VG3 A;  1UBV A;  3G4D A;  2H8O A;  2F9K F;  5EAS A;  5B0I A;  4LTZ A;  4WK5 A;  3P5P A;  4OMH A;  4F62 A;  4MC0 A;  4RYP A;  5A0I A;  4LIX A;  5B02 A;  2Z4Y A;  3M01 A;  3N3D A;  1YHM A;  1YYT A;  3EGT A;  5ER8 A;  1V4I A;  3LJI A;  3VJB A;  4P0V A;  5C05 A;  3WEF A;  1N24 A;  3LMD A;  5IK0 A;  4PVX F;  5DJP F;  3P41 A;  4GA3 A;  2P1C A;  4RXD A;  5IKH A;  4XQS F;  2ZCO A;  2EWG A;  3EZ3 A;  3LDW A;  3VJ9 A;  4NKF A;  3PKO A;  2E8W A;  2J1P A;  4KWD A;  5A0K A;  4E1E A;  5IL3 A;  1YYU A;  5EAU A;  3M00 A;  2Q9Y A;  2FOR A;  3N5J F;  2F8C F;  4LA5 A;  2ZCS A;  5DW7 A;  3WCL A;  2VF6 A;  5ERO A;  3WCA A;  3KRC B;  3PYA A;  5CG6 A;  3AQ0 A;  4NFJ F;  3N45 F;  4KFA A;  3KRP B;  5DIQ F;  4NKE A;  3PYB A;  3WE9 A;  3SDV A;  4RXE A;  1JFG A;  1YJ4 A;  4JXY A;  2OA6 A;  3PH7 A;  5B0J A;  3PDE A;  1HM7 A;  1HXG A;  5HN7 A;  1WL1 A;  3KRF A;  2AET A;  4MC8 A;  5A0J A;  2F7M F;  3LSN A;  2O1O A;  2Q9Z A;  5ILK A;  2ZEV A;  1N22 A;  1KIZ A;  5ILZ A;  5DHK A;  4KVW A;  3LLW A;  1RQJ A;  4KVI A;  5B0M A;  4LFE A;  1YV5 A;  5IK6 A;  3ID0 A;  4LTV A;  2AZL A;  4E9U A;  1VG2 A;  3WEK A;  2E8V A;  3TFP A;  5JA0 F;  3S9V A;  1V4J A;  2ZY1 A;  1HM4 A;  5IMN A;  3CKE A;  4LZ0 A;  3M9U A;  1YQ7 A;  3WCD A;  1HX9 A;  3AQC B;  2E90 A;  3DYF A;  3ASX A;  4KQ5 A;  3DYG A;  4LA6 A;  1N20 A;  4LPH F;  5AEL A;  3WCM A;  4RXC A;  2AEL A;  2OPN A;  3B7L A;  3LEE A;  3Q2Q A;  3QKC A;  5ERN A;  3RYE A;  3WEG A;  5ILJ A;  5E8K A;  1JFA A;  4KK2 A;  4NFK F;  2FTZ A;  2PS7 A;  3NPK A;  2Q80 A;  3NPR A;  2I19 A;  4H5D F;  4PVY F;  4P0W A;  3V66 A;  3VJE A;  4EA2 A;  2E92 A;  1UBW A;  2PS6 A;  4JZX A;  5AFX A;  5IVG A;  3N49 F;  3M02 A;  3LGK A;  4QXS F;  5ILY A;  3P5R A;  3KRC A;  2ZEU A;  3P8R A;  1N1B A;  2AZK A;  3ZMB A;  5ERM A;  4RXA A;  4NFI F;  1DGP A;  3KRP A;  5ILD A;  4JVJ F;  1VG7 A;  3N3L F;  1YYR A;  3ICK A;  5E8L A;  3LZ9 A;  3DYH A;  3VJC A;  4RNQ A;  3CC9 A;  1PS1 A;  2Z7I A;  1N23 A;  4XQR F;  5HN8 A;  3WJN A;  4P0X A;  5ILH A;  2F8Z F;  2QIS A;  5H9D A;  1VG6 A;  5DHI A;  4DHD A;  4LPG F;  4EA0 A;  1HXA A;  3ZCD A;  4LFV F;  3VJ8 A;  4GAX A;  2E8T A;  1V4K A;  2ONG A;  2PS8 A;  3WEH A;  4F6V A;  2F92 F;  3VJD A;  5CG5 A;  3QQV A;  1YYQ A;  1WMW A;  3OAB B;  3BNY A;  4LXW A;  3RBM A;  2E95 A;  1WL0 A;  3SAE A;  3Q30 A;  3RMG A;  4DEM F;  1RTR A;  5AHU B;  5IMI A;  5DGM F;  3WEI A;  5DZ2 A;  2AEK A;  4LZC A;  5B00 A;  4DXJ A;  4EA1 A;  3V1X A;  4H5C F;  3WJK A;  3WEJ A;  4OMG A;  2E94 A;  4FJQ A;  3WCE A;  5JV1 F;  3LOM A;  4OKZ A;  2Z52 A;  4JXN A;  3OAC B;  3M0G A;  3AQB B;  3TFV A;  2OPM A;  5B0K A;  3LGZ B;  4LOB A;  5E8H A;  4LLS A;  3W7F A;  3WCI A;  3BNX A;  3ICM A;  1WL2 A;  3N1W F;  2ZCQ A;  4LZ3 A;  3WSA A;  1UBY A;  4KQS A;  1KIY A;  3ACW A;  1HXC A;  3KRF B;  5HNA A;  3OYR A;  3ADZ A;  2E8U A;  3TFN A;  3V1V A;  3KRA B;  1WL3 A;  3NF2 A;  3ACY A;  4KVD A;  3UCA A;  5B03 A;  3WCB A;  5DJR F;  5IMP A;  4MC3 A;  3AE0 A;  4F6X A;  1EZF A;  4KKM A;  5DGS F;  5I1U A;  3RYW A;  3ICZ A;  4E9Z A;  2Z78 A;  3S4J A;  3TC1 A;  1FPS A;  1WKZ A;  3IPI A;  5IK9 A;  4UMJ A;  3EFQ A;  5EAT A;  2ONH A;  3ZMC A;  3N46 F;  4KQU A;  1ZW5 A;  3KRO B;  2DH4 A;  5IL8 A;  4DZW A;  5DGN F;  3SDT A;  4JZB A;  3N6K F;  3ZOU A;  3MZV A;  3SDR A;  3SDQ A;  3ICN A;  3N1V F;  2RAH A;  5DJV F;  4DWG A;  2PS5 A;  3OAB A;  2Z4W A;  4DI5 A;  2Z7H A;  2Z50 A;  3WCH A;  3CP6 A;  3WCC A;  2ZCR A;  5JV2 F;  1RQI A;  3VJA A;  4N1Z F;  4LFG A;  3P8L A;  5ILI A;  2Z4X A;  2E91 A;  4NUA A;  3N0G A;  5KSX F;  5B0L A;  5JUZ F;  4L2X F;  4JYX A;  3WCJ A;  1YYS A;  5IKA A;  3LK5 A;  3OAC A;  4KPJ A;  2Z4Z A;  3Q1O A;  4Q23 A;  2OGD A;  4QPF A;  1YHL A;  2F94 F;  2J1O A;  1DI1 A;  2Q58 A;  2Z4V A;  3ACX A;  3N0F A;  2PS4 A;  4XQT F;  1UBX A;  3WCF A;  1WY0 A;  4KPD A;  4LLT A;  1V4H A;  3TS7 A;  4OGU A;  2E8X A;  2F89 F;  3WJO A;  4N9U A;  2E4O A;  4KVY A;  3ZL6 A;  3KRA A;  1N1Z A;  5B01 A;  2AZJ A;  5JV0 F;  1VG4 A;  3SDU A;  4ZQ8 A;  4OKM A;  3WC9 A;  4DWB A;  3IBA A;  3Q2Z A;  3KB9 A;  5AYP A;  5IN8 A;  3APZ A;  2J5C A;  5HN9 A;  1YHK A;  3KRO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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