4OT1A

Structural basis for the recognition of human cytomegalovirus glycoprotein b by the neutralizing human antibody sm5-1
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
113
structure length
113
Chain Sequence
EDLDEGIMVVYKRNIAGSGCQLTFWEASERTIRSEAEDSYHFSSAKMTATFLSKKQEVNMSDSALDCVRDEAAAKLQQIFNTSYNQTYEKYGNVSVFETTGGLVVFWQGIKQK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the recognition of human cytomegalovirus glycoprotein B by a neutralizing human antibody.
pubmed doi rcsb
molecule tags Viral protein/immune system
source organism Human cytomegalovirus
molecule keywords Envelope glycoprotein B
total genus 27
structure length 113
sequence length 113
ec nomenclature
pdb deposition date 2014-02-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF17416 Glycoprot_B_PH1 Herpesvirus Glycoprotein B
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.100 Mainly Beta Roll PH-domain like PH-domain like 4ot1A00
3NW8A 4OSNA 4HSIA 3NWDA 3FVCA 2GUMA 3NWFA 4L1RA 4OT1A 3NWAA
chains in the Genus database with same CATH superfamily
1XODA 1EVHA 2DKPA 5JP4A 1X1FA 3T06A 4A6FA 3B77A 2DX5A 4Z2MB 2Q13A 4Z2NA 4HB2B 5DIFB 2ROVA 5KQ1A 1U5EA 3P6AA 4GOUA 2CRFA 5C79A 5D3XA 2LG1A 1X11A 5LG4B 2ADZA 3F0WA 2I1JA 3LJUX 4WJ7A 5D3VA 3GYOA 3TCAA 3NWFA 5L81A 5I2MA 3PZDA 4WSFA 4WVFB 3BINA 4BBKA 2MKRA 4QJ3B 2CODA 1U2BA 3FSSA 4Y94A 2E2XA 4MK0A 2YT2A 2YVCA 2K8EA 3PEGA 4PQ0A 1DDVA 5DHFB 1DROA 2DLWA 4HAXB 3SYXA 1MK7B 4TKNA 1U5GA 4L6EA 3GYPA 1K5GB 2Y8GA 2N23A 1V61A 1RJ2A 1WI1A 4HSIA 1KZ7A 4KHBB 4F7HA 1UPQA 2EC1A 4K81A 1V5UA 5J3TA 3M1IB 2RNRB 1U5DA 2R0DA 1UNRA 1BAKA 3G9WA 4DXAB 1P6SA 2CAYA 3DCXA 2HTHB 2H7EA 2OTXA 1N3HA 4KHAA 1PFJA 2J59M 1RRPB 2D9ZA 3DXCA 2YT0A 4L1RA 1WJ1A 2D4QA 1MIZB 1AQCA 2IFSA 2YRYA 1LB1A 2K49A 1Z87A 1W1GA 1MPHA 1BTNA 5C5BB 4F7GA 3UZTA 1LW3A 4DX90 2FJUB 2D9XA 3V5WA 3NWAA 5KCVA 2DHKA 5HE2A 3OANA 1TXDA 1P3RA 2XQNM 1XR0B 1XKEA 2ROZB 1IRSA 3KSYA 5FI1A 4GN1A 5JLJB 1ZSQA 5J3QA 5HE3A 5GOWB 2NBVA 2DKQA 4QXAB 2KUQA 3KRXA 3WA0A 4HB4B 3MDBC 2J0JA 2R09A 2NZ8B 3D8FA 3QIJA 4DX8A 4C0AA 1J19A 1KZGA 2KIEA 4HAZB 5CLLB 1TQZA 1FHOA 4IAPA 5JHHA 1KI1B 2IYBA 3F5RA 3SUZA 2UZSA 1P5TA 5D27A 4MY6A 2Z0PA 2HE7A 2AEHA 1W1DA 2P0HA 2VRWB 3DXDA 2PZ1A 3U12A 4K17A 3FVCA 2DYNA 2GJYA 2NMBA 3TO1A 5DHAB 3ODXA 3P7ZA 1M7RA 3OHMB 5J3YA 3PVUA 1X1GA 2RRFA 1M7EA 2Z4DA 2VSZA 2GCJA 1ZC3B 3HQCA 1SGHA 4HB0B 1DBHA 5DI9B 2DYQA 3AU4A 5EFXA 2L1CA 2DX1A 1WGQA 1UNQA 2KGXB 1V5PA 3CXBB 1QC6A 5D3YA 5HE0A 4D6WA 2EMSA 2BCJA 1I7AA 2LYDA 2ZPYA 3DXEA 3NW8A 2RUKB 4HAUB 2DN6A 2W2XD 2RLOA 4KHBA 3TW1A 1MIXA 2UZRA 1DDWA 5FI0A 2RVBB 3WYFB 2J0KA 2V76A 3PSCA 2GUMA 3TVVA 1QQGA 2J0MA 3A98B 4CHMA 2FJLA 4H8SA 1B55A 2D9VA 5KQ4A 2COFA 3ZVRA 4GNKB 2KCJA 3FM8C 2P0DA 2Z13A 1TJ6A 2DTCA 2COCA 1E5WA 3ULBA 4CSQA 1EAZA 2YT1A 1U5FA 4A6HA 2OQBA 2D9YA 1OQNA 2LOZA 2P8VA 1Q67A 2L2IA 4A5KA 5C5BA 1DYNA 1X86A 1NTVA 3ODWA 2DHIA 3D8DA 3SV1A 2QKMA 3NWDA 2ELBA 2Z14A 4NY0A 3A8PA 1ZC4B 2R2YA 4DIXA 2MDXA 5LOPB 1MKEA 3PG7A 2CY5A 2GCLA 1XD4A 2YS5A 1UPRA 4OT1A 1V5MA 1ZYIA 1H4RA 1U27A 2K2JA 2ZKMX 1OY2A 3HSAA 2RSGA 4OSNA 1FHWA 2Z0OA 1NU2A 4CHJA 4ZRJA 3IVFA 3U8ZA 1UEFA 1GC7A 1ZM0A 1FGYA 3AU5A 2EJ8A 4GMXB 4K2PA 3KZ1A 5LONB 2H7DA 1WG7A 1FAOA 1FGZA 1XCGA 4D0NB 2YS1A 1UNPA 2VKIA 4A6FB 1NI2A 4YL8A 5I2SA 3CIKA 2LKOA 4HB3B 3ULCA 1FHXA 5C16A 1W1HA 4DBBA 5C6RA 1GG3A 3PP2A 3QWMA 4B6HA 3HK0A 3PVLA 2K2UA 4ZRIA 1WJMA 1K5DB 1ISNA 2QKLA 1XX0A 4EJNA 5M4YB 3MPXA 2Y7BA 2LULA 1BTKA 5JHGA 1MI1A 2YF0A 4GMVA 2K00A 4ZRKA 3AJ4A 4GPTB 4NSWA 5CLQB 2COAA 3ML4A 4IOYX 3N7CA 5IRSA 2Y8FA 1T77A 2P0FA 2I1KA 2X18A 1U29A 3SO6A 1Y5OA 3D8EA 1MK9B 2LOXA 2M38A 3O96A 5DH9B 2N0YA 1H10A 2Z59A 3FEHA 1X05A 4QJ5B 2DFKA 3SNHA 3KRWA 3HIEA 2YS3A 4HDOA 4HAVB 3ZDTA 3KY9A 4GXBA 1WVHA 1PLSA 2GS0A 4KVGB 4CYEA 4EKUA 3VIAA 4XWXA 1EGXA 4KAXB 2EMTA 2DA0A 2KR0A 1GC6A 3NSUA 2G35A 4MT7A 2KIGA 1NTYA 2DHJA 1PMSA 2I5FA 4HATB 4HAWB 3VOQA 2ELAA 4P7IA 3A58A 2MFQA 1MAIA 4EMOA 4QJ4B 2W2WA 4PNKA 3BJIA 4IFSA 1DDMA 3A8QA 1I2HA 2KUPA 1J0WA 2D10A 3U7DA 3QBVB 4F7UP 1AWEA 4HHVA 1FB8A 3TFMA 2I5CA 4A6KA 5D3WA 1WGUA 2MWNB 3RCPA 3PVWA 4K2OA 3X23A 3ODOA 1Y19B 2W2XC 4YONA 1V88A 3HW2B 1OMWA 2Z0QA 4GZUA 4HDQA 2CY4A 2UVMA 2RGNB 5HE1A 1V89A 2M14A 2AL6A 2D2QA 2YSZA 2D11A 2D9WA 1SHCA 2JP2A 1BWNA 1FOEA 1ZVRA 1EF1A 4HAYB 4TYZA 4KHOA
chains in the Genus database with same CATH topology
2KR0A 2RRFA 2Z4DA 2GCLA 2GCJA 2KIGA 4CSQA 2NBVA 2Z59A 4QJ5B 2K49A 4OT1A 5LG4B 1ZYIA 4PQ0A 4QXAB 2KUQA 3A58A 3HIEA 2GUMA 3FVCA 3GYOA 3TVVA 4QJ4B 3NWFA 5I2SA 5M4YB 5I2MA 2ZKMX 4IFSA 4Z2MB 2FJUB 3NWAA 3GYPA 4Z2NA 4QJ3B 4OSNA 3TO1A 3FSSA 4D6WA 4KHAA 4IOYX 2KIEA 3NW8A 4HSIA 3NWDA 2YT2A 3U12A 2K8EA 5IRSA 2Z14A 4KHBB 4GNKB 4GOUA 3OHMB 4KHBA 4L1RA 2R2YA 3TW1A 4DIXA 2Z13A 4KHOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NW8 A;  4OSN A;  4HSI A;  3NWD A;  3FVC A;  2GUM A;  3NWF A;  4L1R A;  4OT1 A;  3NWA A; 
#chains in the Genus database with same CATH topology
 1XOD A;  1EVH A;  2DKP A;  5JP4 A;  1X1F A;  3T06 A;  4A6F A;  3B77 A;  2DX5 A;  4Z2M B;  2Q13 A;  4Z2N A;  4HB2 B;  5DIF B;  2ROV A;  5KQ1 A;  1U5E A;  3P6A A;  4GOU A;  2CRF A;  5C79 A;  5D3X A;  2LG1 A;  1X11 A;  5LG4 B;  2ADZ A;  3F0W A;  2I1J A;  3LJU X;  4WJ7 A;  5D3V A;  3GYO A;  3TCA A;  3NWF A;  5L81 A;  5I2M A;  3PZD A;  4WSF A;  4WVF B;  3BIN A;  4BBK A;  2MKR A;  4QJ3 B;  2COD A;  1U2B A;  3FSS A;  4Y94 A;  2E2X A;  4MK0 A;  2YT2 A;  2YVC A;  2K8E A;  3PEG A;  4PQ0 A;  1DDV A;  5DHF B;  1DRO A;  2DLW A;  4HAX B;  3SYX A;  1MK7 B;  4TKN A;  1U5G A;  4L6E A;  3GYP A;  1K5G B;  2Y8G A;  2N23 A;  1V61 A;  1RJ2 A;  1WI1 A;  4HSI A;  1KZ7 A;  4KHB B;  4F7H A;  1UPQ A;  2EC1 A;  4K81 A;  1V5U A;  5J3T A;  3M1I B;  2RNR B;  1U5D A;  2R0D A;  1UNR A;  1BAK A;  3G9W A;  4DXA B;  1P6S A;  2CAY A;  3DCX A;  2HTH B;  2H7E A;  2OTX A;  1N3H A;  4KHA A;  1PFJ A;  2J59 M;  1RRP B;  2D9Z A;  3DXC A;  2YT0 A;  4L1R A;  1WJ1 A;  2D4Q A;  1MIZ B;  1AQC A;  2IFS A;  2YRY A;  1LB1 A;  2K49 A;  1Z87 A;  1W1G A;  1MPH A;  1BTN A;  5C5B B;  4F7G A;  3UZT A;  1LW3 A;  4DX9 0;  2FJU B;  2D9X A;  3V5W A;  3NWA A;  5KCV A;  2DHK A;  5HE2 A;  3OAN A;  1TXD A;  1P3R A;  2XQN M;  1XR0 B;  1XKE A;  2ROZ B;  1IRS A;  3KSY A;  5FI1 A;  4GN1 A;  5JLJ B;  1ZSQ A;  5J3Q A;  5HE3 A;  5GOW B;  2NBV A;  2DKQ A;  4QXA B;  2KUQ A;  3KRX A;  3WA0 A;  4HB4 B;  3MDB C;  2J0J A;  2R09 A;  2NZ8 B;  3D8F A;  3QIJ A;  4DX8 A;  4C0A A;  1J19 A;  1KZG A;  2KIE A;  4HAZ B;  5CLL B;  1TQZ A;  1FHO A;  4IAP A;  5JHH A;  1KI1 B;  2IYB A;  3F5R A;  3SUZ A;  2UZS A;  1P5T A;  5D27 A;  4MY6 A;  2Z0P A;  2HE7 A;  2AEH A;  1W1D A;  2P0H A;  2VRW B;  3DXD A;  2PZ1 A;  3U12 A;  4K17 A;  3FVC A;  2DYN A;  2GJY A;  2NMB A;  3TO1 A;  5DHA B;  3ODX A;  3P7Z A;  1M7R A;  3OHM B;  5J3Y A;  3PVU A;  1X1G A;  2RRF A;  1M7E A;  2Z4D A;  2VSZ A;  2GCJ A;  1ZC3 B;  3HQC A;  1SGH A;  4HB0 B;  1DBH A;  5DI9 B;  2DYQ A;  3AU4 A;  5EFX A;  2L1C A;  2DX1 A;  1WGQ A;  1UNQ A;  2KGX B;  1V5P A;  3CXB B;  1QC6 A;  5D3Y A;  5HE0 A;  4D6W A;  2EMS A;  2BCJ A;  1I7A A;  2LYD A;  2ZPY A;  3DXE A;  3NW8 A;  2RUK B;  4HAU B;  2DN6 A;  2W2X D;  2RLO A;  4KHB A;  3TW1 A;  1MIX A;  2UZR A;  1DDW A;  5FI0 A;  2RVB B;  3WYF B;  2J0K A;  2V76 A;  3PSC A;  2GUM A;  3TVV A;  1QQG A;  2J0M A;  3A98 B;  4CHM A;  2FJL A;  4H8S A;  1B55 A;  2D9V A;  5KQ4 A;  2COF A;  3ZVR A;  4GNK B;  2KCJ A;  3FM8 C;  2P0D A;  2Z13 A;  1TJ6 A;  2DTC A;  2COC A;  1E5W A;  3ULB A;  4CSQ A;  1EAZ A;  2YT1 A;  1U5F A;  4A6H A;  2OQB A;  2D9Y A;  1OQN A;  2LOZ A;  2P8V A;  1Q67 A;  2L2I A;  4A5K A;  5C5B A;  1DYN A;  1X86 A;  1NTV A;  3ODW A;  2DHI A;  3D8D A;  3SV1 A;  2QKM A;  3NWD A;  2ELB A;  2Z14 A;  4NY0 A;  3A8P A;  1ZC4 B;  2R2Y A;  4DIX A;  2MDX A;  5LOP B;  1MKE A;  3PG7 A;  2CY5 A;  2GCL A;  1XD4 A;  2YS5 A;  1UPR A;  4OT1 A;  1V5M A;  1ZYI A;  1H4R A;  1U27 A;  2K2J A;  2ZKM X;  1OY2 A;  3HSA A;  2RSG A;  4OSN A;  1FHW A;  2Z0O A;  1NU2 A;  4CHJ A;  4ZRJ A;  3IVF A;  3U8Z A;  1UEF A;  1GC7 A;  1ZM0 A;  1FGY A;  3AU5 A;  2EJ8 A;  4GMX B;  4K2P A;  3KZ1 A;  5LON B;  2H7D A;  1WG7 A;  1FAO A;  1FGZ A;  1XCG A;  4D0N B;  2YS1 A;  1UNP A;  2VKI A;  4A6F B;  1NI2 A;  4YL8 A;  5I2S A;  3CIK A;  2LKO A;  4HB3 B;  3ULC A;  1FHX A;  5C16 A;  1W1H A;  4DBB A;  5C6R A;  1GG3 A;  3PP2 A;  3QWM A;  4B6H A;  3HK0 A;  3PVL A;  2K2U A;  4ZRI A;  1WJM A;  1K5D B;  1ISN A;  2QKL A;  1XX0 A;  4EJN A;  5M4Y B;  3MPX A;  2Y7B A;  2LUL A;  1BTK A;  5JHG A;  1MI1 A;  2YF0 A;  4GMV A;  2K00 A;  4ZRK A;  3AJ4 A;  4GPT B;  4NSW A;  5CLQ B;  2COA A;  3ML4 A;  4IOY X;  3N7C A;  5IRS A;  2Y8F A;  1T77 A;  2P0F A;  2I1K A;  2X18 A;  1U29 A;  3SO6 A;  1Y5O A;  3D8E A;  1MK9 B;  2LOX A;  2M38 A;  3O96 A;  5DH9 B;  2N0Y A;  1H10 A;  2Z59 A;  3FEH A;  1X05 A;  4QJ5 B;  2DFK A;  3SNH A;  3KRW A;  3HIE A;  2YS3 A;  4HDO A;  4HAV B;  3ZDT A;  3KY9 A;  4GXB A;  1WVH A;  1PLS A;  2GS0 A;  4KVG B;  4CYE A;  4EKU A;  3VIA A;  4XWX A;  1EGX A;  4KAX B;  2EMT A;  2DA0 A;  2KR0 A;  1GC6 A;  3NSU A;  2G35 A;  4MT7 A;  2KIG A;  1NTY A;  2DHJ A;  1PMS A;  2I5F A;  4HAT B;  4HAW B;  3VOQ A;  2ELA A;  4P7I A;  3A58 A;  2MFQ A;  1MAI A;  4EMO A;  4QJ4 B;  2W2W A;  4PNK A;  3BJI A;  4IFS A;  1DDM A;  3A8Q A;  1I2H A;  2KUP A;  1J0W A;  2D10 A;  3U7D A;  3QBV B;  4F7U P;  1AWE A;  4HHV A;  1FB8 A;  3TFM A;  2I5C A;  4A6K A;  5D3W A;  1WGU A;  2MWN B;  3RCP A;  3PVW A;  4K2O A;  3X23 A;  3ODO A;  1Y19 B;  2W2X C;  4YON A;  1V88 A;  3HW2 B;  1OMW A;  2Z0Q A;  4GZU A;  4HDQ A;  2CY4 A;  2UVM A;  2RGN B;  5HE1 A;  1V89 A;  2M14 A;  2AL6 A;  2D2Q A;  2YSZ A;  2D11 A;  2D9W A;  1SHC A;  2JP2 A;  1BWN A;  1FOE A;  1ZVR A;  1EF1 A;  4HAY B;  4TYZ A;  4KHO A; 
#chains in the Genus database with same CATH homology
 2KR0 A;  2RRF A;  2Z4D A;  2GCL A;  2GCJ A;  2KIG A;  4CSQ A;  2NBV A;  2Z59 A;  4QJ5 B;  2K49 A;  4OT1 A;  5LG4 B;  1ZYI A;  4PQ0 A;  4QXA B;  2KUQ A;  3A58 A;  3HIE A;  2GUM A;  3FVC A;  3GYO A;  3TVV A;  4QJ4 B;  3NWF A;  5I2S A;  5M4Y B;  5I2M A;  2ZKM X;  4IFS A;  4Z2M B;  2FJU B;  3NWA A;  3GYP A;  4Z2N A;  4QJ3 B;  4OSN A;  3TO1 A;  3FSS A;  4D6W A;  4KHA A;  4IOY X;  2KIE A;  3NW8 A;  4HSI A;  3NWD A;  2YT2 A;  3U12 A;  2K8E A;  5IRS A;  2Z14 A;  4KHB B;  4GNK B;  4GOU A;  3OHM B;  4KHB A;  4L1R A;  2R2Y A;  3TW1 A;  4DIX A;  2Z13 A;  4KHO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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