4P3RA

Cryogenic wt dhfr, time-averaged ensemble
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
159
structure length
159
Chain Sequence
b'MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Dihydrofolate reductase
publication title Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Oxidoreductase
total genus 43
structure length 159
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2014-03-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4p3rA00
3FYVX 4Q67A 5DFRA 2O7PA 1QZFA 1PDBA 4G3MA 3KJRA 4DDRA 4DP3A 1DRHA 3DL6A 1RA3A 3E0BA 2ITHA 1RX1A 5CCCA 3NXRA 3JSUA 1S3UA 4M2XA 2FZHA 3EEKA 4PDJA 3GHWA 1HFPA 1JUVA 2W3BA 3TD8A 2LF1A 4XT7A 1DR2A 1OHKA 2HM9A 8DFRA 4QHVA 1RD7A 4XT5A 1RX5A 3SRRX 1DAJA 1LUDA 4XECX 3NRRA 3KY8A 1DRAA 5DXVA 1BZFA 4H97A 3NZCX 1DIUA 4PSYA 1RF7A 4LAGX 1RC4A 4Q0EA 1HFQA 4TU5X 4LAHX 4EIGA 1MVSA 5HVEA 3F0VX 4QJCA 1KMVA 2BLAA 4XE6X 5FDAA 1SEJA 3FRBX 2CD2A 2DHFA 3L3RA 1DHFA 3JWFA 3FQVA 4P3QA 1CD2A 2CIGA 3M09A 4KM2A 3IRNA 3NZ9X 3DG8A 1RX9A 2GD9A 4PSSA 3OAFA 1U71A 4EJ1A 4P68A 5U26A 2BL9A 4KJJA 5HQZA 1LY4A 4HA7A 3HBBA 1DRFA 3JW5A 3F8ZA 1AI9A 4I1NA 4ELEA 1DYJA 3SRUX 3QLXA 5JA3A 1KMSA 1DYIA 3K47A 3KJSA 3IRMA 1LY3A 1RX2A 1J3JA 3TQAA 4KFJA 4KNEA 4M6KA 4I13A 4X5HA 1MVTA 1VJ3A 3FRAX 4H96A 1J3KA 5U27A 3F0XX 3K74A 3JVXA 3TQBA 3IA5A 3QLZA 3IX9A 1ZDRA 3GYFA 2C2SA 4QJZD 3ROAA 5HF2X 3JWMA 5HSUA 2HXVA 1PD9A 3F0QX 5CC9A 3S9UA 1DR4A 1JOMA 3FQZA 1RH3A 4KJKA 3FQFA 4EIZA 3EIGA 1PD8A 1TDRA 4ECKA 1CZ3A 3EEMA 3TQ9A 4KJLA 6DFRA 3NXOA 3FQCA 3QFXA 1DRBA 1DISA 3FY9X 2ANQA 5HT5A 3GI2A 3JWKA 2C2TA 4KL9A 3KGYA 3INVA 4KLXA 3QLWA 2ANOA 1D1GA 4IXGX 2D5NA 3ZPGA 1RA9A 4H95A 3HJ3A 3D80A 3NXVA 3SGYA 3VCOA 4HOFA 1RX6A 3CD2A 4HOEA 4XT4A 3K2HA 1DDSA 2OBCA 4X5JA 5ECXA 4QI9A 2ZZAA 3TQ8A 2W3WA 3NZAX 4FHBA 3QLRA 4PTHA 3SRWX 3R33A 1DG7A 3K45A 1RA2A 1KLKA 3SAIA 3KFYA 3DL5A 4QLGA 4ELFA 2FZJA 2W3VA 2W3MA 3SH2A 1DYHA 4LEKX 5HT4A 1DR7A 5HVBA 2KGKA 2H2QA 1RB2A 3N0HA 3QLSA 3F0UX 4H98A 1S3YA 3JTWA 3QLYA 1YHOA 1RE7A 3NXXA 4DPDA 3QGTA 3CSEA 4OSGA 4M7VA 2P4GA 3S3VA 3SA2A 1DLRA 4EILA 3FYWX 3NZ6X 3EEJA 3RG9A 4HA9A 3IA4A 2W9TA 3M08A 3CLBA 1DR6A 3NU0A 3I3RA 2INQA 4PTJA 3LG4A 3CL9A 1RA1A 5HQYA 1S3WA 5HPBA 1DG8A 4DFRA 3FRDX 3ZPCA 3JW3A 3UM6A 2BLCA 1DF7A 4X5IA 4M7UA 4X5GA 1HFRA 1DHJA 3QL3A 4M6JA 5HSRA 4ELBA 4XT8A 2B3ZA 4CD2A 1JOLA 3D84X 2HQPA 3SR5X 4XRBA 2W9GA 3NTZA 1BOZA 3DFRA 7DFRA 2FZIA 1RX8A 5ECCA 1M79A 2QK8A 1IA4A 5E8QA 3OCHA 3FL8A 4KBNA 3Q1HA 3GHCA 4KY8A 1DYRA 3SRQX 1DLSA 2W3AA 3F0BX 1U70A 2W9SA 4RGCA 3QG2A 1VDRA 4P66A 3I8AX 2AZNA 1M78A 4FGHA 4IXED 5HI6A 3EELA 1IA3A 5HUIA 2L28A 3NZBX 4KAKA 3FY8X 3UM8A 1AO8A 1RX4A 4GH8A 4NX6A 3FL9A 4Q0DA 3DGAA 3JWCA 1RX7A 1S3VA 3QYOA 3DAUA 3NZDA 3QL0A 1AOEA 1RA8A 4NX7A 2DRCA 4FGGA 3FQOA 4QLEA 4KYAA 1DREA 4IXFX 1DHIA 3FQ0A 3IROA 4ELHA 1E26A 2XW7A 3UM5A 4Q6AA 4DPHA 5HF0X 2OIPA 1OHJA 3DATA 1U72A 4KD7A 4P3RA 1IA1A 3DRCA 1DDRA 3NXYA 4KM0A 1RX3A 3SA1A 4KY4A 1DR5A 4XT6A 2G6VA 3RO9A 4HOGA 3NXTA 3F91A 5EAJA 4QLFA 1DR1A 1IA2A 3GHVA 3EX8A 3FRFX 3F8YA 4ELGA 2W9HA 1J3IA 4KEBA 1RG7A 3SQYX 3FREX 4LAEX 5JG0X 1DR3A 2JYBA 4G95A 4G8ZX 1DG5A 4OR7A 2D0KA 3SRSX 1M7AA 4PSTA 4X5FA 1RB3A 2BLBA 3F0SX 3FS6A 4M6LA 3QYLA 3S7AA
chains in the Genus database with same CATH superfamily
3FYVX 4Q67A 5DFRA 2O7PA 1QZFA 1PDBA 4G3MA 3KJRA 4DDRA 4DP3A 1DRHA 3DL6A 1RA3A 3E0BA 2ITHA 1RX1A 5CCCA 3NXRA 3JSUA 1S3UA 4M2XA 2FZHA 3EEKA 4PDJA 3GHWA 1HFPA 1JUVA 2W3BA 3TD8A 2LF1A 4XT7A 1DR2A 1OHKA 2HM9A 8DFRA 4QHVA 1RD7A 4XT5A 1RX5A 3SRRX 1DAJA 1LUDA 4XECX 3NRRA 3KY8A 1DRAA 5DXVA 1BZFA 4H97A 3NZCX 1DIUA 4PSYA 1RF7A 4LAGX 1RC4A 4Q0EA 1HFQA 4TU5X 4LAHX 4EIGA 1MVSA 5HVEA 3F0VX 4QJCA 1KMVA 2BLAA 4XE6X 5FDAA 1SEJA 3FRBX 2CD2A 2DHFA 3L3RA 1DHFA 3JWFA 3FQVA 4P3QA 1CD2A 2CIGA 3M09A 4KM2A 3IRNA 3NZ9X 3DG8A 1RX9A 2GD9A 4PSSA 3OAFA 1U71A 4EJ1A 4P68A 5U26A 2BL9A 4KJJA 5HQZA 1LY4A 4HA7A 3HBBA 1DRFA 3JW5A 3F8ZA 1AI9A 4I1NA 4ELEA 1DYJA 3SRUX 3QLXA 5JA3A 1KMSA 1DYIA 3K47A 3KJSA 3IRMA 1LY3A 1RX2A 1J3JA 3TQAA 4KFJA 4KNEA 4M6KA 4I13A 4X5HA 1MVTA 1VJ3A 3FRAX 4H96A 1J3KA 5U27A 3F0XX 3K74A 3JVXA 3TQBA 3IA5A 3QLZA 3IX9A 1ZDRA 3GYFA 2C2SA 4QJZD 3ROAA 5HF2X 3JWMA 5HSUA 2HXVA 1PD9A 3F0QX 5CC9A 3S9UA 1DR4A 1JOMA 3FQZA 1RH3A 4KJKA 3FQFA 4EIZA 3EIGA 1PD8A 1TDRA 4ECKA 1CZ3A 3EEMA 3TQ9A 4KJLA 6DFRA 3NXOA 3FQCA 3QFXA 1DRBA 1DISA 3FY9X 2ANQA 5HT5A 3GI2A 3JWKA 2C2TA 4KL9A 3KGYA 3INVA 4KLXA 3QLWA 2ANOA 1D1GA 4IXGX 2D5NA 3ZPGA 1RA9A 4H95A 3HJ3A 3D80A 3NXVA 3SGYA 3VCOA 4HOFA 1RX6A 3CD2A 4HOEA 4XT4A 3K2HA 1DDSA 2OBCA 4X5JA 5ECXA 4QI9A 2ZZAA 3TQ8A 2W3WA 3NZAX 4FHBA 3QLRA 4PTHA 3SRWX 3R33A 1DG7A 3K45A 1RA2A 1KLKA 3SAIA 3KFYA 3DL5A 4QLGA 4ELFA 2FZJA 2W3VA 2W3MA 3SH2A 1DYHA 4LEKX 5HT4A 1DR7A 5HVBA 2KGKA 2H2QA 1RB2A 3N0HA 3QLSA 3F0UX 4H98A 1S3YA 3JTWA 3QLYA 1YHOA 1RE7A 3NXXA 4DPDA 3QGTA 3CSEA 4OSGA 4M7VA 2P4GA 3S3VA 3SA2A 1DLRA 4EILA 3FYWX 3NZ6X 3EEJA 3RG9A 4HA9A 3IA4A 2W9TA 3M08A 3CLBA 1DR6A 3NU0A 3I3RA 2INQA 4PTJA 3LG4A 3CL9A 1RA1A 5HQYA 1S3WA 5HPBA 1DG8A 4DFRA 3FRDX 3ZPCA 3JW3A 3UM6A 2BLCA 1DF7A 4X5IA 4M7UA 4X5GA 1HFRA 1DHJA 3QL3A 4M6JA 5HSRA 4ELBA 4XT8A 2B3ZA 4CD2A 1JOLA 3D84X 2HQPA 3SR5X 4XRBA 2W9GA 3NTZA 1BOZA 3DFRA 7DFRA 2FZIA 1RX8A 5ECCA 1M79A 2QK8A 1IA4A 5E8QA 3OCHA 3FL8A 4KBNA 3Q1HA 3GHCA 4KY8A 1DYRA 3SRQX 1DLSA 2W3AA 3F0BX 1U70A 2W9SA 4RGCA 3QG2A 1VDRA 4P66A 3I8AX 2AZNA 1M78A 4FGHA 4IXED 5HI6A 3EELA 1IA3A 5HUIA 2L28A 3NZBX 4KAKA 3FY8X 3UM8A 1AO8A 1RX4A 4GH8A 4NX6A 3FL9A 4Q0DA 3DGAA 3JWCA 1RX7A 1S3VA 3QYOA 3DAUA 3NZDA 3QL0A 1AOEA 1RA8A 4NX7A 2DRCA 4FGGA 3FQOA 4QLEA 4KYAA 1DREA 4IXFX 1DHIA 3FQ0A 3IROA 4ELHA 1E26A 2XW7A 3UM5A 4Q6AA 4DPHA 5HF0X 2OIPA 1OHJA 3DATA 1U72A 4KD7A 4P3RA 1IA1A 3DRCA 1DDRA 3NXYA 4KM0A 1RX3A 3SA1A 4KY4A 1DR5A 4XT6A 2G6VA 3RO9A 4HOGA 3NXTA 3F91A 5EAJA 4QLFA 1DR1A 1IA2A 3GHVA 3EX8A 3FRFX 3F8YA 4ELGA 2W9HA 1J3IA 4KEBA 1RG7A 3SQYX 3FREX 4LAEX 5JG0X 1DR3A 2JYBA 4G95A 4G8ZX 1DG5A 4OR7A 2D0KA 3SRSX 1M7AA 4PSTA 4X5FA 1RB3A 2BLBA 3F0SX 3FS6A 4M6LA 3QYLA 3S7AA
chains in the Genus database with same CATH topology
3FYVX 4Q67A 5DFRA 2O7PA 1QZFA 1PDBA 4G3MA 3KJRA 4DDRA 4DP3A 1DRHA 3DL6A 1RA3A 3E0BA 2ITHA 1RX1A 5CCCA 3NXRA 3JSUA 1S3UA 4M2XA 2FZHA 3EEKA 4PDJA 3GHWA 1HFPA 1JUVA 2W3BA 3TD8A 2LF1A 4XT7A 1DR2A 1OHKA 2HM9A 8DFRA 4QHVA 1RD7A 4XT5A 1RX5A 3SRRX 1DAJA 1LUDA 4XECX 3NRRA 3KY8A 1DRAA 5DXVA 1BZFA 4H97A 3NZCX 1DIUA 4PSYA 1RF7A 4LAGX 1RC4A 4Q0EA 1HFQA 4TU5X 4LAHX 4EIGA 1MVSA 5HVEA 3F0VX 4QJCA 1KMVA 2BLAA 4XE6X 5FDAA 1SEJA 3FRBX 2CD2A 2DHFA 3L3RA 1DHFA 3JWFA 3FQVA 4P3QA 1CD2A 2CIGA 3M09A 4KM2A 3IRNA 3NZ9X 3DG8A 1RX9A 2GD9A 4PSSA 3OAFA 1U71A 4EJ1A 4P68A 5U26A 2BL9A 4KJJA 5HQZA 1LY4A 4HA7A 3HBBA 1DRFA 3JW5A 3F8ZA 1AI9A 4I1NA 4ELEA 1DYJA 3SRUX 3QLXA 5JA3A 1KMSA 1DYIA 3K47A 3KJSA 3IRMA 1LY3A 1RX2A 1J3JA 3TQAA 4KFJA 4KNEA 4M6KA 4I13A 4X5HA 1MVTA 1VJ3A 3FRAX 4H96A 1J3KA 5U27A 3F0XX 3K74A 3JVXA 3TQBA 3IA5A 3QLZA 3IX9A 1ZDRA 3GYFA 2C2SA 4QJZD 3ROAA 5HF2X 3JWMA 5HSUA 2HXVA 1PD9A 3F0QX 5CC9A 3S9UA 1DR4A 1JOMA 3FQZA 1RH3A 4KJKA 3FQFA 4EIZA 3EIGA 1PD8A 1TDRA 4ECKA 1CZ3A 3EEMA 3TQ9A 4KJLA 6DFRA 3NXOA 3FQCA 3QFXA 1DRBA 1DISA 3FY9X 2ANQA 5HT5A 3GI2A 3JWKA 2C2TA 4KL9A 3KGYA 3INVA 4KLXA 3QLWA 2ANOA 1D1GA 4IXGX 2D5NA 3ZPGA 1RA9A 4H95A 3HJ3A 3D80A 3NXVA 3SGYA 3VCOA 4HOFA 1RX6A 3CD2A 4HOEA 4XT4A 3K2HA 1DDSA 2OBCA 4X5JA 5ECXA 4QI9A 2ZZAA 3TQ8A 2W3WA 3NZAX 4FHBA 3QLRA 4PTHA 3SRWX 3R33A 1DG7A 3K45A 1RA2A 1KLKA 3SAIA 3KFYA 3DL5A 4QLGA 4ELFA 2FZJA 2W3VA 2W3MA 3SH2A 1DYHA 4LEKX 5HT4A 1DR7A 5HVBA 2KGKA 2H2QA 1RB2A 3N0HA 3QLSA 3F0UX 4H98A 1S3YA 3JTWA 3QLYA 1YHOA 1RE7A 3NXXA 4DPDA 3QGTA 3CSEA 4OSGA 4M7VA 2P4GA 3S3VA 3SA2A 1DLRA 4EILA 3FYWX 3NZ6X 3EEJA 3RG9A 4HA9A 3IA4A 2W9TA 3M08A 3CLBA 1DR6A 3NU0A 3I3RA 2INQA 4PTJA 3LG4A 3CL9A 1RA1A 5HQYA 1S3WA 5HPBA 1DG8A 4DFRA 3FRDX 3ZPCA 3JW3A 3UM6A 2BLCA 1DF7A 4X5IA 4M7UA 4X5GA 1HFRA 1DHJA 3QL3A 4M6JA 5HSRA 4ELBA 4XT8A 2B3ZA 4CD2A 1JOLA 3D84X 2HQPA 3SR5X 4XRBA 2W9GA 3NTZA 1BOZA 3DFRA 7DFRA 2FZIA 1RX8A 5ECCA 1M79A 2QK8A 1IA4A 5E8QA 3OCHA 3FL8A 4KBNA 3Q1HA 3GHCA 4KY8A 1DYRA 3SRQX 1DLSA 2W3AA 3F0BX 1U70A 2W9SA 4RGCA 3QG2A 1VDRA 4P66A 3I8AX 2AZNA 1M78A 4FGHA 4IXED 5HI6A 3EELA 1IA3A 5HUIA 2L28A 3NZBX 4KAKA 3FY8X 3UM8A 1AO8A 1RX4A 4GH8A 4NX6A 3FL9A 4Q0DA 3DGAA 3JWCA 1RX7A 1S3VA 3QYOA 3DAUA 3NZDA 3QL0A 1AOEA 1RA8A 4NX7A 2DRCA 4FGGA 3FQOA 4QLEA 4KYAA 1DREA 4IXFX 1DHIA 3FQ0A 3IROA 4ELHA 1E26A 2XW7A 3UM5A 4Q6AA 4DPHA 5HF0X 2OIPA 1OHJA 3DATA 1U72A 4KD7A 4P3RA 1IA1A 3DRCA 1DDRA 3NXYA 4KM0A 1RX3A 3SA1A 4KY4A 1DR5A 4XT6A 2G6VA 3RO9A 4HOGA 3NXTA 3F91A 5EAJA 4QLFA 1DR1A 1IA2A 3GHVA 3EX8A 3FRFX 3F8YA 4ELGA 2W9HA 1J3IA 4KEBA 1RG7A 3SQYX 3FREX 4LAEX 5JG0X 1DR3A 2JYBA 4G95A 4G8ZX 1DG5A 4OR7A 2D0KA 3SRSX 1M7AA 4PSTA 4X5FA 1RB3A 2BLBA 3F0SX 3FS6A 4M6LA 3QYLA 3S7AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FYV X;  4Q67 A;  5DFR A;  2O7P A;  1QZF A;  1PDB A;  4G3M A;  3KJR A;  4DDR A;  4DP3 A;  1DRH A;  3DL6 A;  1RA3 A;  3E0B A;  2ITH A;  1RX1 A;  5CCC A;  3NXR A;  3JSU A;  1S3U A;  4M2X A;  2FZH A;  3EEK A;  4PDJ A;  3GHW A;  1HFP A;  1JUV A;  2W3B A;  3TD8 A;  2LF1 A;  4XT7 A;  1DR2 A;  1OHK A;  2HM9 A;  8DFR A;  4QHV A;  1RD7 A;  4XT5 A;  1RX5 A;  3SRR X;  1DAJ A;  1LUD A;  4XEC X;  3NRR A;  3KY8 A;  1DRA A;  5DXV A;  1BZF A;  4H97 A;  3NZC X;  1DIU A;  4PSY A;  1RF7 A;  4LAG X;  1RC4 A;  4Q0E A;  1HFQ A;  4TU5 X;  4LAH X;  4EIG A;  1MVS A;  5HVE A;  3F0V X;  4QJC A;  1KMV A;  2BLA A;  4XE6 X;  5FDA A;  1SEJ A;  3FRB X;  2CD2 A;  2DHF A;  3L3R A;  1DHF A;  3JWF A;  3FQV A;  4P3Q A;  1CD2 A;  2CIG A;  3M09 A;  4KM2 A;  3IRN A;  3NZ9 X;  3DG8 A;  1RX9 A;  2GD9 A;  4PSS A;  3OAF A;  1U71 A;  4EJ1 A;  4P68 A;  5U26 A;  2BL9 A;  4KJJ A;  5HQZ A;  1LY4 A;  4HA7 A;  3HBB A;  1DRF A;  3JW5 A;  3F8Z A;  1AI9 A;  4I1N A;  4ELE A;  1DYJ A;  3SRU X;  3QLX A;  5JA3 A;  1KMS A;  1DYI A;  3K47 A;  3KJS A;  3IRM A;  1LY3 A;  1RX2 A;  1J3J A;  3TQA A;  4KFJ A;  4KNE A;  4M6K A;  4I13 A;  4X5H A;  1MVT A;  1VJ3 A;  3FRA X;  4H96 A;  1J3K A;  5U27 A;  3F0X X;  3K74 A;  3JVX A;  3TQB A;  3IA5 A;  3QLZ A;  3IX9 A;  1ZDR A;  3GYF A;  2C2S A;  4QJZ D;  3ROA A;  5HF2 X;  3JWM A;  5HSU A;  2HXV A;  1PD9 A;  3F0Q X;  5CC9 A;  3S9U A;  1DR4 A;  1JOM A;  3FQZ A;  1RH3 A;  4KJK A;  3FQF A;  4EIZ A;  3EIG A;  1PD8 A;  1TDR A;  4ECK A;  1CZ3 A;  3EEM A;  3TQ9 A;  4KJL A;  6DFR A;  3NXO A;  3FQC A;  3QFX A;  1DRB A;  1DIS A;  3FY9 X;  2ANQ A;  5HT5 A;  3GI2 A;  3JWK A;  2C2T A;  4KL9 A;  3KGY A;  3INV A;  4KLX A;  3QLW A;  2ANO A;  1D1G A;  4IXG X;  2D5N A;  3ZPG A;  1RA9 A;  4H95 A;  3HJ3 A;  3D80 A;  3NXV A;  3SGY A;  3VCO A;  4HOF A;  1RX6 A;  3CD2 A;  4HOE A;  4XT4 A;  3K2H A;  1DDS A;  2OBC A;  4X5J A;  5ECX A;  4QI9 A;  2ZZA A;  3TQ8 A;  2W3W A;  3NZA X;  4FHB A;  3QLR A;  4PTH A;  3SRW X;  3R33 A;  1DG7 A;  3K45 A;  1RA2 A;  1KLK A;  3SAI A;  3KFY A;  3DL5 A;  4QLG A;  4ELF A;  2FZJ A;  2W3V A;  2W3M A;  3SH2 A;  1DYH A;  4LEK X;  5HT4 A;  1DR7 A;  5HVB A;  2KGK A;  2H2Q A;  1RB2 A;  3N0H A;  3QLS A;  3F0U X;  4H98 A;  1S3Y A;  3JTW A;  3QLY A;  1YHO A;  1RE7 A;  3NXX A;  4DPD A;  3QGT A;  3CSE A;  4OSG A;  4M7V A;  2P4G A;  3S3V A;  3SA2 A;  1DLR A;  4EIL A;  3FYW X;  3NZ6 X;  3EEJ A;  3RG9 A;  4HA9 A;  3IA4 A;  2W9T A;  3M08 A;  3CLB A;  1DR6 A;  3NU0 A;  3I3R A;  2INQ A;  4PTJ A;  3LG4 A;  3CL9 A;  1RA1 A;  5HQY A;  1S3W A;  5HPB A;  1DG8 A;  4DFR A;  3FRD X;  3ZPC A;  3JW3 A;  3UM6 A;  2BLC A;  1DF7 A;  4X5I A;  4M7U A;  4X5G A;  1HFR A;  1DHJ A;  3QL3 A;  4M6J A;  5HSR A;  4ELB A;  4XT8 A;  2B3Z A;  4CD2 A;  1JOL A;  3D84 X;  2HQP A;  3SR5 X;  4XRB A;  2W9G A;  3NTZ A;  1BOZ A;  3DFR A;  7DFR A;  2FZI A;  1RX8 A;  5ECC A;  1M79 A;  2QK8 A;  1IA4 A;  5E8Q A;  3OCH A;  3FL8 A;  4KBN A;  3Q1H A;  3GHC A;  4KY8 A;  1DYR A;  3SRQ X;  1DLS A;  2W3A A;  3F0B X;  1U70 A;  2W9S A;  4RGC A;  3QG2 A;  1VDR A;  4P66 A;  3I8A X;  2AZN A;  1M78 A;  4FGH A;  4IXE D;  5HI6 A;  3EEL A;  1IA3 A;  5HUI A;  2L28 A;  3NZB X;  4KAK A;  3FY8 X;  3UM8 A;  1AO8 A;  1RX4 A;  4GH8 A;  4NX6 A;  3FL9 A;  4Q0D A;  3DGA A;  3JWC A;  1RX7 A;  1S3V A;  3QYO A;  3DAU A;  3NZD A;  3QL0 A;  1AOE A;  1RA8 A;  4NX7 A;  2DRC A;  4FGG A;  3FQO A;  4QLE A;  4KYA A;  1DRE A;  4IXF X;  1DHI A;  3FQ0 A;  3IRO A;  4ELH A;  1E26 A;  2XW7 A;  3UM5 A;  4Q6A A;  4DPH A;  5HF0 X;  2OIP A;  1OHJ A;  3DAT A;  1U72 A;  4KD7 A;  4P3R A;  1IA1 A;  3DRC A;  1DDR A;  3NXY A;  4KM0 A;  1RX3 A;  3SA1 A;  4KY4 A;  1DR5 A;  4XT6 A;  2G6V A;  3RO9 A;  4HOG A;  3NXT A;  3F91 A;  5EAJ A;  4QLF A;  1DR1 A;  1IA2 A;  3GHV A;  3EX8 A;  3FRF X;  3F8Y A;  4ELG A;  2W9H A;  1J3I A;  4KEB A;  1RG7 A;  3SQY X;  3FRE X;  4LAE X;  5JG0 X;  1DR3 A;  2JYB A;  4G95 A;  4G8Z X;  1DG5 A;  4OR7 A;  2D0K A;  3SRS X;  1M7A A;  4PST A;  4X5F A;  1RB3 A;  2BLB A;  3F0S X;  3FS6 A;  4M6L A;  3QYL A;  3S7A A; 
#chains in the Genus database with same CATH topology
 3FYV X;  4Q67 A;  5DFR A;  2O7P A;  1QZF A;  1PDB A;  4G3M A;  3KJR A;  4DDR A;  4DP3 A;  1DRH A;  3DL6 A;  1RA3 A;  3E0B A;  2ITH A;  1RX1 A;  5CCC A;  3NXR A;  3JSU A;  1S3U A;  4M2X A;  2FZH A;  3EEK A;  4PDJ A;  3GHW A;  1HFP A;  1JUV A;  2W3B A;  3TD8 A;  2LF1 A;  4XT7 A;  1DR2 A;  1OHK A;  2HM9 A;  8DFR A;  4QHV A;  1RD7 A;  4XT5 A;  1RX5 A;  3SRR X;  1DAJ A;  1LUD A;  4XEC X;  3NRR A;  3KY8 A;  1DRA A;  5DXV A;  1BZF A;  4H97 A;  3NZC X;  1DIU A;  4PSY A;  1RF7 A;  4LAG X;  1RC4 A;  4Q0E A;  1HFQ A;  4TU5 X;  4LAH X;  4EIG A;  1MVS A;  5HVE A;  3F0V X;  4QJC A;  1KMV A;  2BLA A;  4XE6 X;  5FDA A;  1SEJ A;  3FRB X;  2CD2 A;  2DHF A;  3L3R A;  1DHF A;  3JWF A;  3FQV A;  4P3Q A;  1CD2 A;  2CIG A;  3M09 A;  4KM2 A;  3IRN A;  3NZ9 X;  3DG8 A;  1RX9 A;  2GD9 A;  4PSS A;  3OAF A;  1U71 A;  4EJ1 A;  4P68 A;  5U26 A;  2BL9 A;  4KJJ A;  5HQZ A;  1LY4 A;  4HA7 A;  3HBB A;  1DRF A;  3JW5 A;  3F8Z A;  1AI9 A;  4I1N A;  4ELE A;  1DYJ A;  3SRU X;  3QLX A;  5JA3 A;  1KMS A;  1DYI A;  3K47 A;  3KJS A;  3IRM A;  1LY3 A;  1RX2 A;  1J3J A;  3TQA A;  4KFJ A;  4KNE A;  4M6K A;  4I13 A;  4X5H A;  1MVT A;  1VJ3 A;  3FRA X;  4H96 A;  1J3K A;  5U27 A;  3F0X X;  3K74 A;  3JVX A;  3TQB A;  3IA5 A;  3QLZ A;  3IX9 A;  1ZDR A;  3GYF A;  2C2S A;  4QJZ D;  3ROA A;  5HF2 X;  3JWM A;  5HSU A;  2HXV A;  1PD9 A;  3F0Q X;  5CC9 A;  3S9U A;  1DR4 A;  1JOM A;  3FQZ A;  1RH3 A;  4KJK A;  3FQF A;  4EIZ A;  3EIG A;  1PD8 A;  1TDR A;  4ECK A;  1CZ3 A;  3EEM A;  3TQ9 A;  4KJL A;  6DFR A;  3NXO A;  3FQC A;  3QFX A;  1DRB A;  1DIS A;  3FY9 X;  2ANQ A;  5HT5 A;  3GI2 A;  3JWK A;  2C2T A;  4KL9 A;  3KGY A;  3INV A;  4KLX A;  3QLW A;  2ANO A;  1D1G A;  4IXG X;  2D5N A;  3ZPG A;  1RA9 A;  4H95 A;  3HJ3 A;  3D80 A;  3NXV A;  3SGY A;  3VCO A;  4HOF A;  1RX6 A;  3CD2 A;  4HOE A;  4XT4 A;  3K2H A;  1DDS A;  2OBC A;  4X5J A;  5ECX A;  4QI9 A;  2ZZA A;  3TQ8 A;  2W3W A;  3NZA X;  4FHB A;  3QLR A;  4PTH A;  3SRW X;  3R33 A;  1DG7 A;  3K45 A;  1RA2 A;  1KLK A;  3SAI A;  3KFY A;  3DL5 A;  4QLG A;  4ELF A;  2FZJ A;  2W3V A;  2W3M A;  3SH2 A;  1DYH A;  4LEK X;  5HT4 A;  1DR7 A;  5HVB A;  2KGK A;  2H2Q A;  1RB2 A;  3N0H A;  3QLS A;  3F0U X;  4H98 A;  1S3Y A;  3JTW A;  3QLY A;  1YHO A;  1RE7 A;  3NXX A;  4DPD A;  3QGT A;  3CSE A;  4OSG A;  4M7V A;  2P4G A;  3S3V A;  3SA2 A;  1DLR A;  4EIL A;  3FYW X;  3NZ6 X;  3EEJ A;  3RG9 A;  4HA9 A;  3IA4 A;  2W9T A;  3M08 A;  3CLB A;  1DR6 A;  3NU0 A;  3I3R A;  2INQ A;  4PTJ A;  3LG4 A;  3CL9 A;  1RA1 A;  5HQY A;  1S3W A;  5HPB A;  1DG8 A;  4DFR A;  3FRD X;  3ZPC A;  3JW3 A;  3UM6 A;  2BLC A;  1DF7 A;  4X5I A;  4M7U A;  4X5G A;  1HFR A;  1DHJ A;  3QL3 A;  4M6J A;  5HSR A;  4ELB A;  4XT8 A;  2B3Z A;  4CD2 A;  1JOL A;  3D84 X;  2HQP A;  3SR5 X;  4XRB A;  2W9G A;  3NTZ A;  1BOZ A;  3DFR A;  7DFR A;  2FZI A;  1RX8 A;  5ECC A;  1M79 A;  2QK8 A;  1IA4 A;  5E8Q A;  3OCH A;  3FL8 A;  4KBN A;  3Q1H A;  3GHC A;  4KY8 A;  1DYR A;  3SRQ X;  1DLS A;  2W3A A;  3F0B X;  1U70 A;  2W9S A;  4RGC A;  3QG2 A;  1VDR A;  4P66 A;  3I8A X;  2AZN A;  1M78 A;  4FGH A;  4IXE D;  5HI6 A;  3EEL A;  1IA3 A;  5HUI A;  2L28 A;  3NZB X;  4KAK A;  3FY8 X;  3UM8 A;  1AO8 A;  1RX4 A;  4GH8 A;  4NX6 A;  3FL9 A;  4Q0D A;  3DGA A;  3JWC A;  1RX7 A;  1S3V A;  3QYO A;  3DAU A;  3NZD A;  3QL0 A;  1AOE A;  1RA8 A;  4NX7 A;  2DRC A;  4FGG A;  3FQO A;  4QLE A;  4KYA A;  1DRE A;  4IXF X;  1DHI A;  3FQ0 A;  3IRO A;  4ELH A;  1E26 A;  2XW7 A;  3UM5 A;  4Q6A A;  4DPH A;  5HF0 X;  2OIP A;  1OHJ A;  3DAT A;  1U72 A;  4KD7 A;  4P3R A;  1IA1 A;  3DRC A;  1DDR A;  3NXY A;  4KM0 A;  1RX3 A;  3SA1 A;  4KY4 A;  1DR5 A;  4XT6 A;  2G6V A;  3RO9 A;  4HOG A;  3NXT A;  3F91 A;  5EAJ A;  4QLF A;  1DR1 A;  1IA2 A;  3GHV A;  3EX8 A;  3FRF X;  3F8Y A;  4ELG A;  2W9H A;  1J3I A;  4KEB A;  1RG7 A;  3SQY X;  3FRE X;  4LAE X;  5JG0 X;  1DR3 A;  2JYB A;  4G95 A;  4G8Z X;  1DG5 A;  4OR7 A;  2D0K A;  3SRS X;  1M7A A;  4PST A;  4X5F A;  1RB3 A;  2BLB A;  3F0S X;  3FS6 A;  4M6L A;  3QYL A;  3S7A A; 
#chains in the Genus database with same CATH homology
 3FYV X;  4Q67 A;  5DFR A;  2O7P A;  1QZF A;  1PDB A;  4G3M A;  3KJR A;  4DDR A;  4DP3 A;  1DRH A;  3DL6 A;  1RA3 A;  3E0B A;  2ITH A;  1RX1 A;  5CCC A;  3NXR A;  3JSU A;  1S3U A;  4M2X A;  2FZH A;  3EEK A;  4PDJ A;  3GHW A;  1HFP A;  1JUV A;  2W3B A;  3TD8 A;  2LF1 A;  4XT7 A;  1DR2 A;  1OHK A;  2HM9 A;  8DFR A;  4QHV A;  1RD7 A;  4XT5 A;  1RX5 A;  3SRR X;  1DAJ A;  1LUD A;  4XEC X;  3NRR A;  3KY8 A;  1DRA A;  5DXV A;  1BZF A;  4H97 A;  3NZC X;  1DIU A;  4PSY A;  1RF7 A;  4LAG X;  1RC4 A;  4Q0E A;  1HFQ A;  4TU5 X;  4LAH X;  4EIG A;  1MVS A;  5HVE A;  3F0V X;  4QJC A;  1KMV A;  2BLA A;  4XE6 X;  5FDA A;  1SEJ A;  3FRB X;  2CD2 A;  2DHF A;  3L3R A;  1DHF A;  3JWF A;  3FQV A;  4P3Q A;  1CD2 A;  2CIG A;  3M09 A;  4KM2 A;  3IRN A;  3NZ9 X;  3DG8 A;  1RX9 A;  2GD9 A;  4PSS A;  3OAF A;  1U71 A;  4EJ1 A;  4P68 A;  5U26 A;  2BL9 A;  4KJJ A;  5HQZ A;  1LY4 A;  4HA7 A;  3HBB A;  1DRF A;  3JW5 A;  3F8Z A;  1AI9 A;  4I1N A;  4ELE A;  1DYJ A;  3SRU X;  3QLX A;  5JA3 A;  1KMS A;  1DYI A;  3K47 A;  3KJS A;  3IRM A;  1LY3 A;  1RX2 A;  1J3J A;  3TQA A;  4KFJ A;  4KNE A;  4M6K A;  4I13 A;  4X5H A;  1MVT A;  1VJ3 A;  3FRA X;  4H96 A;  1J3K A;  5U27 A;  3F0X X;  3K74 A;  3JVX A;  3TQB A;  3IA5 A;  3QLZ A;  3IX9 A;  1ZDR A;  3GYF A;  2C2S A;  4QJZ D;  3ROA A;  5HF2 X;  3JWM A;  5HSU A;  2HXV A;  1PD9 A;  3F0Q X;  5CC9 A;  3S9U A;  1DR4 A;  1JOM A;  3FQZ A;  1RH3 A;  4KJK A;  3FQF A;  4EIZ A;  3EIG A;  1PD8 A;  1TDR A;  4ECK A;  1CZ3 A;  3EEM A;  3TQ9 A;  4KJL A;  6DFR A;  3NXO A;  3FQC A;  3QFX A;  1DRB A;  1DIS A;  3FY9 X;  2ANQ A;  5HT5 A;  3GI2 A;  3JWK A;  2C2T A;  4KL9 A;  3KGY A;  3INV A;  4KLX A;  3QLW A;  2ANO A;  1D1G A;  4IXG X;  2D5N A;  3ZPG A;  1RA9 A;  4H95 A;  3HJ3 A;  3D80 A;  3NXV A;  3SGY A;  3VCO A;  4HOF A;  1RX6 A;  3CD2 A;  4HOE A;  4XT4 A;  3K2H A;  1DDS A;  2OBC A;  4X5J A;  5ECX A;  4QI9 A;  2ZZA A;  3TQ8 A;  2W3W A;  3NZA X;  4FHB A;  3QLR A;  4PTH A;  3SRW X;  3R33 A;  1DG7 A;  3K45 A;  1RA2 A;  1KLK A;  3SAI A;  3KFY A;  3DL5 A;  4QLG A;  4ELF A;  2FZJ A;  2W3V A;  2W3M A;  3SH2 A;  1DYH A;  4LEK X;  5HT4 A;  1DR7 A;  5HVB A;  2KGK A;  2H2Q A;  1RB2 A;  3N0H A;  3QLS A;  3F0U X;  4H98 A;  1S3Y A;  3JTW A;  3QLY A;  1YHO A;  1RE7 A;  3NXX A;  4DPD A;  3QGT A;  3CSE A;  4OSG A;  4M7V A;  2P4G A;  3S3V A;  3SA2 A;  1DLR A;  4EIL A;  3FYW X;  3NZ6 X;  3EEJ A;  3RG9 A;  4HA9 A;  3IA4 A;  2W9T A;  3M08 A;  3CLB A;  1DR6 A;  3NU0 A;  3I3R A;  2INQ A;  4PTJ A;  3LG4 A;  3CL9 A;  1RA1 A;  5HQY A;  1S3W A;  5HPB A;  1DG8 A;  4DFR A;  3FRD X;  3ZPC A;  3JW3 A;  3UM6 A;  2BLC A;  1DF7 A;  4X5I A;  4M7U A;  4X5G A;  1HFR A;  1DHJ A;  3QL3 A;  4M6J A;  5HSR A;  4ELB A;  4XT8 A;  2B3Z A;  4CD2 A;  1JOL A;  3D84 X;  2HQP A;  3SR5 X;  4XRB A;  2W9G A;  3NTZ A;  1BOZ A;  3DFR A;  7DFR A;  2FZI A;  1RX8 A;  5ECC A;  1M79 A;  2QK8 A;  1IA4 A;  5E8Q A;  3OCH A;  3FL8 A;  4KBN A;  3Q1H A;  3GHC A;  4KY8 A;  1DYR A;  3SRQ X;  1DLS A;  2W3A A;  3F0B X;  1U70 A;  2W9S A;  4RGC A;  3QG2 A;  1VDR A;  4P66 A;  3I8A X;  2AZN A;  1M78 A;  4FGH A;  4IXE D;  5HI6 A;  3EEL A;  1IA3 A;  5HUI A;  2L28 A;  3NZB X;  4KAK A;  3FY8 X;  3UM8 A;  1AO8 A;  1RX4 A;  4GH8 A;  4NX6 A;  3FL9 A;  4Q0D A;  3DGA A;  3JWC A;  1RX7 A;  1S3V A;  3QYO A;  3DAU A;  3NZD A;  3QL0 A;  1AOE A;  1RA8 A;  4NX7 A;  2DRC A;  4FGG A;  3FQO A;  4QLE A;  4KYA A;  1DRE A;  4IXF X;  1DHI A;  3FQ0 A;  3IRO A;  4ELH A;  1E26 A;  2XW7 A;  3UM5 A;  4Q6A A;  4DPH A;  5HF0 X;  2OIP A;  1OHJ A;  3DAT A;  1U72 A;  4KD7 A;  4P3R A;  1IA1 A;  3DRC A;  1DDR A;  3NXY A;  4KM0 A;  1RX3 A;  3SA1 A;  4KY4 A;  1DR5 A;  4XT6 A;  2G6V A;  3RO9 A;  4HOG A;  3NXT A;  3F91 A;  5EAJ A;  4QLF A;  1DR1 A;  1IA2 A;  3GHV A;  3EX8 A;  3FRF X;  3F8Y A;  4ELG A;  2W9H A;  1J3I A;  4KEB A;  1RG7 A;  3SQY X;  3FRE X;  4LAE X;  5JG0 X;  1DR3 A;  2JYB A;  4G95 A;  4G8Z X;  1DG5 A;  4OR7 A;  2D0K A;  3SRS X;  1M7A A;  4PST A;  4X5F A;  1RB3 A;  2BLB A;  3F0S X;  3FS6 A;  4M6L A;  3QYL A;  3S7A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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