4PTHA

Ensemble model for escherichia coli dihydrofolate reductase at 100k
Total Genus 44
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
159
structure length
158
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR.
pubmed doi rcsb
molecule keywords Dihydrofolate reductase
molecule tags Oxidoreductase
source organism Escherichia coli
total genus 44
structure length 158
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2014-03-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4pthA00
3NTZA 1IA2A 1DDRA 1S3VA 3NXTA 3D84X 1RA3A 3K74A 2HXVA 2HQPA 5U27A 4QLGA 1DHJA 8DFRA 1RA9A 3QLSA 3EEJA 4QHVA 4QJZD 1IA3A 3CSEA 3GHVA 4DP3A 2G6VA 3EX8A 5HSUA 4OR7A 1DLRA 3FRAX 3K47A 3QL0A 3DRCA 3F8ZA 4IXED 4LAGX 1DYRA 3EELA 4HA7A 5HUIA 3GYFA 5HPBA 3F0QX 2HM9A 7DFRA 1DRHA 3SH2A 1RH3A 1SEJA 1DR4A 2W3VA 4Q0EA 1TDRA 5DXVA 5JA3A 5U26A 2L28A 1PDBA 4KYAA 4HA9A 1U72A 4G3MA 2D0KA 4HOGA 4QLFA 4FHBA 4EJ1A 3SA2A 3SQYX 3IROA 4FGHA 1RB3A 5HQYA 4ELHA 4M7UA 3NZCX 4X5FA 4KFJA 1DDSA 3F0SX 2AZNA 3QYOA 3NXXA 1RC4A 3DL6A 4KL9A 1IA1A 3KFYA 3F0BX 4G95A 4KJKA 3FRBX 1VJ3A 3TQBA 2XW7A 1DRBA 1LUDA 3QL3A 3I3RA 1RX4A 4I13A 1ZDRA 3QG2A 6DFRA 1OHKA 4CD2A 3FQ0A 1RA2A 3KGYA 3QLWA 2W3BA 1DR1A 1RE7A 4Q0DA 4KNEA 3JWFA 4XT8A 4PDJA 4KY8A 3NZ9X 1HFQA 4KJJA 3RG9A 1U71A 1RX9A 3JSUA 1DYHA 2QK8A 1RA1A 2BL9A 3SA1A 4PTJA 1HFRA 2FZHA 4XE6X 4I1NA 3ROAA 2GD9A 3QGTA 3I8AX 4EIGA 4EIZA 3SRQX 4LAHX 1RX3A 3SRSX 3FS6A 2W3WA 4KBNA 2JYBA 3QYLA 4G8ZX 1J3JA 2ITHA 3HBBA 4IXGX 5HT5A 5DFRA 1DYIA 3FY8X 4P3RA 4H98A 2W9TA 1JOLA 5JG0X 4M2XA 4P66A 3QLZA 1DHFA 1LY3A 4PSTA 3FQFA 1RX5A 3JVXA 3F91A 1RX6A 3FRFX 4M6KA 1S3WA 3JW3A 3NRRA 3TQAA 4DPDA 3GHCA 1KLKA 4M6LA 2OBCA 3SGYA 3K2HA 4HOEA 4DPHA 4H96A 1KMVA 3HJ3A 2C2TA 1MVSA 3NZDA 1BOZA 3EEKA 4ECKA 5HF0X 3DFRA 1RX2A 4Q6AA 1VDRA 3F8YA 4M7VA 1RG7A 5CC9A 4KAKA 5CCCA 3FQZA 3SRUX 5FDAA 4P3QA 1PD9A 3TQ9A 4XT7A 2O7PA 3DL5A 2ANOA 4LEKX 3DAUA 3ZPCA 2ANQA 2W9HA 3NXRA 4ELFA 3SAIA 4XT4A 4DFRA 4KLXA 2DHFA 3E0BA 1YHOA 1DG8A 1DREA 3QLRA 3IRNA 3SR5X 3F0VX 4QI9A 4ELEA 3FL8A 1RX8A 4XT6A 2W3AA 3F0XX 2H2QA 3GI2A 3UM5A 1DR6A 3QFXA 4OSGA 2INQA 4HOFA 1J3IA 1RF7A 3DGAA 1DF7A 1LY4A 3TD8A 3RO9A 3CL9A 3JTWA 3IA5A 4H95A 4XT5A 4PSYA 3OCHA 3NZ6X 3KJRA 5HVBA 1DRAA 4XECX 1M79A 4IXFX 3SRRX 1BZFA 2W9SA 2B3ZA 3FREX 3Q1HA 4NX7A 3S9UA 1RA8A 2W3MA 3KY8A 3EEMA 3FYWX 3M08A 5HI6A 1DLSA 2BLAA 3NXVA 3NZAX 1PD8A 3OAFA 4DDRA 4KY4A 5EAJA 3JW5A 4KM2A 5HSRA 3L3RA 4TU5X 3DG8A 2BLCA 4P68A 3UM8A 4LAEX 1JUVA 1RD7A 3FRDX 4KD7A 3FQCA 1DYJA 4RGCA 3JWKA 3R33A 3FY9X 1DISA 2DRCA 1U70A 3CD2A 3FL9A 2C2SA 1E26A 4KJLA 4XRBA 3DATA 4EILA 4GH8A 3LG4A 2CIGA 4X5GA 3INVA 4NX6A 3NU0A 1DG5A 3JWCA 1MVTA 1AOEA 3K45A 3F0UX 3QLXA 3FQVA 3GHWA 1DR7A 4ELBA 1DRFA 1CD2A 2FZJA 1D1GA 1DR5A 1J3KA 3IX9A 1CZ3A 2KGKA 2P4GA 4KM0A 4ELGA 2BLBA 3SRWX 1QZFA 1DR2A 5HVEA 1RX1A 3JWMA 1RB2A 3CLBA 5ECXA 3KJSA 4QJCA 2LF1A 4PSSA 1DHIA 2ZZAA 1KMSA 2D5NA 1RX7A 2CD2A 3NZBX 4KEBA 3N0HA 5HT4A 5HQZA 4X5IA 3ZPGA 4M6JA 3FQOA 2W9GA 3UM6A 3QLYA 1HFPA 3TQ8A 1M7AA 3VCOA 3NXOA 3NXYA 3S3VA 1S3UA 1AO8A 2OIPA 4X5HA 3FYVX 3IRMA 5HF2X 4PTHA 3IA4A 4H97A 5E8QA 1S3YA 1M78A 1AI9A 1JOMA 1OHJA 1DR3A 1DAJA 1DG7A 3M09A 3EIGA 1IA4A 1DIUA 2FZIA 3S7AA 4FGGA 4QLEA 5ECCA 4X5JA 4Q67A 3D80A
chains in the Genus database with same CATH superfamily
3NTZA 1IA2A 1DDRA 1S3VA 3NXTA 3D84X 1RA3A 3K74A 2HXVA 2HQPA 5U27A 4QLGA 1DHJA 8DFRA 1RA9A 3QLSA 3EEJA 4QHVA 4QJZD 1IA3A 3CSEA 3GHVA 4DP3A 2G6VA 3EX8A 5HSUA 4OR7A 1DLRA 3FRAX 3K47A 3QL0A 3DRCA 3F8ZA 4IXED 4LAGX 1DYRA 3EELA 4HA7A 5HUIA 3GYFA 5HPBA 3F0QX 2HM9A 7DFRA 1DRHA 3SH2A 1RH3A 1SEJA 1DR4A 2W3VA 4Q0EA 1TDRA 5DXVA 5JA3A 5U26A 2L28A 1PDBA 4KYAA 4HA9A 1U72A 4G3MA 2D0KA 4HOGA 4QLFA 4FHBA 4EJ1A 3SA2A 3SQYX 3IROA 4FGHA 1RB3A 5HQYA 4ELHA 4M7UA 3NZCX 4X5FA 4KFJA 1DDSA 3F0SX 2AZNA 3QYOA 3NXXA 1RC4A 3DL6A 4KL9A 1IA1A 3KFYA 3F0BX 4G95A 4KJKA 3FRBX 1VJ3A 3TQBA 2XW7A 1DRBA 1LUDA 3QL3A 3I3RA 1RX4A 4I13A 1ZDRA 3QG2A 6DFRA 1OHKA 4CD2A 3FQ0A 1RA2A 3KGYA 3QLWA 2W3BA 1DR1A 1RE7A 4Q0DA 4KNEA 3JWFA 4XT8A 4PDJA 4KY8A 3NZ9X 1HFQA 4KJJA 3RG9A 1U71A 1RX9A 3JSUA 1DYHA 2QK8A 1RA1A 2BL9A 3SA1A 4PTJA 1HFRA 2FZHA 4XE6X 4I1NA 3ROAA 2GD9A 3QGTA 3I8AX 4EIGA 4EIZA 3SRQX 4LAHX 1RX3A 3SRSX 3FS6A 2W3WA 4KBNA 2JYBA 3QYLA 4G8ZX 1J3JA 2ITHA 3HBBA 4IXGX 5HT5A 5DFRA 1DYIA 3FY8X 4P3RA 4H98A 2W9TA 1JOLA 5JG0X 4M2XA 4P66A 3QLZA 1DHFA 1LY3A 4PSTA 3FQFA 1RX5A 3JVXA 3F91A 1RX6A 3FRFX 4M6KA 1S3WA 3JW3A 3NRRA 3TQAA 4DPDA 3GHCA 1KLKA 4M6LA 2OBCA 3SGYA 3K2HA 4HOEA 4DPHA 4H96A 1KMVA 3HJ3A 2C2TA 1MVSA 3NZDA 1BOZA 3EEKA 4ECKA 5HF0X 3DFRA 1RX2A 4Q6AA 1VDRA 3F8YA 4M7VA 1RG7A 5CC9A 4KAKA 5CCCA 3FQZA 3SRUX 5FDAA 4P3QA 1PD9A 3TQ9A 4XT7A 2O7PA 3DL5A 2ANOA 4LEKX 3DAUA 3ZPCA 2ANQA 2W9HA 3NXRA 4ELFA 3SAIA 4XT4A 4DFRA 4KLXA 2DHFA 3E0BA 1YHOA 1DG8A 1DREA 3QLRA 3IRNA 3SR5X 3F0VX 4QI9A 4ELEA 3FL8A 1RX8A 4XT6A 2W3AA 3F0XX 2H2QA 3GI2A 3UM5A 1DR6A 3QFXA 4OSGA 2INQA 4HOFA 1J3IA 1RF7A 3DGAA 1DF7A 1LY4A 3TD8A 3RO9A 3CL9A 3JTWA 3IA5A 4H95A 4XT5A 4PSYA 3OCHA 3NZ6X 3KJRA 5HVBA 1DRAA 4XECX 1M79A 4IXFX 3SRRX 1BZFA 2W9SA 2B3ZA 3FREX 3Q1HA 4NX7A 3S9UA 1RA8A 2W3MA 3KY8A 3EEMA 3FYWX 3M08A 5HI6A 1DLSA 2BLAA 3NXVA 3NZAX 1PD8A 3OAFA 4DDRA 4KY4A 5EAJA 3JW5A 4KM2A 5HSRA 3L3RA 4TU5X 3DG8A 2BLCA 4P68A 3UM8A 4LAEX 1JUVA 1RD7A 3FRDX 4KD7A 3FQCA 1DYJA 4RGCA 3JWKA 3R33A 3FY9X 1DISA 2DRCA 1U70A 3CD2A 3FL9A 2C2SA 1E26A 4KJLA 4XRBA 3DATA 4EILA 4GH8A 3LG4A 2CIGA 4X5GA 3INVA 4NX6A 3NU0A 1DG5A 3JWCA 1MVTA 1AOEA 3K45A 3F0UX 3QLXA 3FQVA 3GHWA 1DR7A 4ELBA 1DRFA 1CD2A 2FZJA 1D1GA 1DR5A 1J3KA 3IX9A 1CZ3A 2KGKA 2P4GA 4KM0A 4ELGA 2BLBA 3SRWX 1QZFA 1DR2A 5HVEA 1RX1A 3JWMA 1RB2A 3CLBA 5ECXA 3KJSA 4QJCA 2LF1A 4PSSA 1DHIA 2ZZAA 1KMSA 2D5NA 1RX7A 2CD2A 3NZBX 4KEBA 3N0HA 5HT4A 5HQZA 4X5IA 3ZPGA 4M6JA 3FQOA 2W9GA 3UM6A 3QLYA 1HFPA 3TQ8A 1M7AA 3VCOA 3NXOA 3NXYA 3S3VA 1S3UA 1AO8A 2OIPA 4X5HA 3FYVX 3IRMA 5HF2X 4PTHA 3IA4A 4H97A 5E8QA 1S3YA 1M78A 1AI9A 1JOMA 1OHJA 1DR3A 1DAJA 1DG7A 3M09A 3EIGA 1IA4A 1DIUA 2FZIA 3S7AA 4FGGA 4QLEA 5ECCA 4X5JA 4Q67A 3D80A
chains in the Genus database with same CATH topology
3NTZA 1IA2A 1DDRA 1S3VA 3NXTA 3D84X 1RA3A 3K74A 2HXVA 2HQPA 5U27A 4QLGA 1DHJA 8DFRA 1RA9A 3QLSA 3EEJA 4QHVA 4QJZD 1IA3A 3CSEA 3GHVA 4DP3A 2G6VA 3EX8A 5HSUA 4OR7A 1DLRA 3FRAX 3K47A 3QL0A 3DRCA 3F8ZA 4IXED 4LAGX 1DYRA 3EELA 4HA7A 5HUIA 3GYFA 5HPBA 3F0QX 2HM9A 7DFRA 1DRHA 3SH2A 1RH3A 1SEJA 1DR4A 2W3VA 4Q0EA 1TDRA 5DXVA 5JA3A 5U26A 2L28A 1PDBA 4KYAA 4HA9A 1U72A 4G3MA 2D0KA 4HOGA 4QLFA 4FHBA 4EJ1A 3SA2A 3SQYX 3IROA 4FGHA 1RB3A 5HQYA 4ELHA 4M7UA 3NZCX 4X5FA 4KFJA 1DDSA 3F0SX 2AZNA 3QYOA 3NXXA 1RC4A 3DL6A 4KL9A 1IA1A 3KFYA 3F0BX 4G95A 4KJKA 3FRBX 1VJ3A 3TQBA 2XW7A 1DRBA 1LUDA 3QL3A 3I3RA 1RX4A 4I13A 1ZDRA 3QG2A 6DFRA 1OHKA 4CD2A 3FQ0A 1RA2A 3KGYA 3QLWA 2W3BA 1DR1A 1RE7A 4Q0DA 4KNEA 3JWFA 4XT8A 4PDJA 4KY8A 3NZ9X 1HFQA 4KJJA 3RG9A 1U71A 1RX9A 3JSUA 1DYHA 2QK8A 1RA1A 2BL9A 3SA1A 4PTJA 1HFRA 2FZHA 4XE6X 4I1NA 3ROAA 2GD9A 3QGTA 3I8AX 4EIGA 4EIZA 3SRQX 4LAHX 1RX3A 3SRSX 3FS6A 2W3WA 4KBNA 2JYBA 3QYLA 4G8ZX 1J3JA 2ITHA 3HBBA 4IXGX 5HT5A 5DFRA 1DYIA 3FY8X 4P3RA 4H98A 2W9TA 1JOLA 5JG0X 4M2XA 4P66A 3QLZA 1DHFA 1LY3A 4PSTA 3FQFA 1RX5A 3JVXA 3F91A 1RX6A 3FRFX 4M6KA 1S3WA 3JW3A 3NRRA 3TQAA 4DPDA 3GHCA 1KLKA 4M6LA 2OBCA 3SGYA 3K2HA 4HOEA 4DPHA 4H96A 1KMVA 3HJ3A 2C2TA 1MVSA 3NZDA 1BOZA 3EEKA 4ECKA 5HF0X 3DFRA 1RX2A 4Q6AA 1VDRA 3F8YA 4M7VA 1RG7A 5CC9A 4KAKA 5CCCA 3FQZA 3SRUX 5FDAA 4P3QA 1PD9A 3TQ9A 4XT7A 2O7PA 3DL5A 2ANOA 4LEKX 3DAUA 3ZPCA 2ANQA 2W9HA 3NXRA 4ELFA 3SAIA 4XT4A 4DFRA 4KLXA 2DHFA 3E0BA 1YHOA 1DG8A 1DREA 3QLRA 3IRNA 3SR5X 3F0VX 4QI9A 4ELEA 3FL8A 1RX8A 4XT6A 2W3AA 3F0XX 2H2QA 3GI2A 3UM5A 1DR6A 3QFXA 4OSGA 2INQA 4HOFA 1J3IA 1RF7A 3DGAA 1DF7A 1LY4A 3TD8A 3RO9A 3CL9A 3JTWA 3IA5A 4H95A 4XT5A 4PSYA 3OCHA 3NZ6X 3KJRA 5HVBA 1DRAA 4XECX 1M79A 4IXFX 3SRRX 1BZFA 2W9SA 2B3ZA 3FREX 3Q1HA 4NX7A 3S9UA 1RA8A 2W3MA 3KY8A 3EEMA 3FYWX 3M08A 5HI6A 1DLSA 2BLAA 3NXVA 3NZAX 1PD8A 3OAFA 4DDRA 4KY4A 5EAJA 3JW5A 4KM2A 5HSRA 3L3RA 4TU5X 3DG8A 2BLCA 4P68A 3UM8A 4LAEX 1JUVA 1RD7A 3FRDX 4KD7A 3FQCA 1DYJA 4RGCA 3JWKA 3R33A 3FY9X 1DISA 2DRCA 1U70A 3CD2A 3FL9A 2C2SA 1E26A 4KJLA 4XRBA 3DATA 4EILA 4GH8A 3LG4A 2CIGA 4X5GA 3INVA 4NX6A 3NU0A 1DG5A 3JWCA 1MVTA 1AOEA 3K45A 3F0UX 3QLXA 3FQVA 3GHWA 1DR7A 4ELBA 1DRFA 1CD2A 2FZJA 1D1GA 1DR5A 1J3KA 3IX9A 1CZ3A 2KGKA 2P4GA 4KM0A 4ELGA 2BLBA 3SRWX 1QZFA 1DR2A 5HVEA 1RX1A 3JWMA 1RB2A 3CLBA 5ECXA 3KJSA 4QJCA 2LF1A 4PSSA 1DHIA 2ZZAA 1KMSA 2D5NA 1RX7A 2CD2A 3NZBX 4KEBA 3N0HA 5HT4A 5HQZA 4X5IA 3ZPGA 4M6JA 3FQOA 2W9GA 3UM6A 3QLYA 1HFPA 3TQ8A 1M7AA 3VCOA 3NXOA 3NXYA 3S3VA 1S3UA 1AO8A 2OIPA 4X5HA 3FYVX 3IRMA 5HF2X 4PTHA 3IA4A 4H97A 5E8QA 1S3YA 1M78A 1AI9A 1JOMA 1OHJA 1DR3A 1DAJA 1DG7A 3M09A 3EIGA 1IA4A 1DIUA 2FZIA 3S7AA 4FGGA 4QLEA 5ECCA 4X5JA 4Q67A 3D80A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NTZ A;  1IA2 A;  1DDR A;  1S3V A;  3NXT A;  3D84 X;  1RA3 A;  3K74 A;  2HXV A;  2HQP A;  5U27 A;  4QLG A;  1DHJ A;  8DFR A;  1RA9 A;  3QLS A;  3EEJ A;  4QHV A;  4QJZ D;  1IA3 A;  3CSE A;  3GHV A;  4DP3 A;  2G6V A;  3EX8 A;  5HSU A;  4OR7 A;  1DLR A;  3FRA X;  3K47 A;  3QL0 A;  3DRC A;  3F8Z A;  4IXE D;  4LAG X;  1DYR A;  3EEL A;  4HA7 A;  5HUI A;  3GYF A;  5HPB A;  3F0Q X;  2HM9 A;  7DFR A;  1DRH A;  3SH2 A;  1RH3 A;  1SEJ A;  1DR4 A;  2W3V A;  4Q0E A;  1TDR A;  5DXV A;  5JA3 A;  5U26 A;  2L28 A;  1PDB A;  4KYA A;  4HA9 A;  1U72 A;  4G3M A;  2D0K A;  4HOG A;  4QLF A;  4FHB A;  4EJ1 A;  3SA2 A;  3SQY X;  3IRO A;  4FGH A;  1RB3 A;  5HQY A;  4ELH A;  4M7U A;  3NZC X;  4X5F A;  4KFJ A;  1DDS A;  3F0S X;  2AZN A;  3QYO A;  3NXX A;  1RC4 A;  3DL6 A;  4KL9 A;  1IA1 A;  3KFY A;  3F0B X;  4G95 A;  4KJK A;  3FRB X;  1VJ3 A;  3TQB A;  2XW7 A;  1DRB A;  1LUD A;  3QL3 A;  3I3R A;  1RX4 A;  4I13 A;  1ZDR A;  3QG2 A;  6DFR A;  1OHK A;  4CD2 A;  3FQ0 A;  1RA2 A;  3KGY A;  3QLW A;  2W3B A;  1DR1 A;  1RE7 A;  4Q0D A;  4KNE A;  3JWF A;  4XT8 A;  4PDJ A;  4KY8 A;  3NZ9 X;  1HFQ A;  4KJJ A;  3RG9 A;  1U71 A;  1RX9 A;  3JSU A;  1DYH A;  2QK8 A;  1RA1 A;  2BL9 A;  3SA1 A;  4PTJ A;  1HFR A;  2FZH A;  4XE6 X;  4I1N A;  3ROA A;  2GD9 A;  3QGT A;  3I8A X;  4EIG A;  4EIZ A;  3SRQ X;  4LAH X;  1RX3 A;  3SRS X;  3FS6 A;  2W3W A;  4KBN A;  2JYB A;  3QYL A;  4G8Z X;  1J3J A;  2ITH A;  3HBB A;  4IXG X;  5HT5 A;  5DFR A;  1DYI A;  3FY8 X;  4P3R A;  4H98 A;  2W9T A;  1JOL A;  5JG0 X;  4M2X A;  4P66 A;  3QLZ A;  1DHF A;  1LY3 A;  4PST A;  3FQF A;  1RX5 A;  3JVX A;  3F91 A;  1RX6 A;  3FRF X;  4M6K A;  1S3W A;  3JW3 A;  3NRR A;  3TQA A;  4DPD A;  3GHC A;  1KLK A;  4M6L A;  2OBC A;  3SGY A;  3K2H A;  4HOE A;  4DPH A;  4H96 A;  1KMV A;  3HJ3 A;  2C2T A;  1MVS A;  3NZD A;  1BOZ A;  3EEK A;  4ECK A;  5HF0 X;  3DFR A;  1RX2 A;  4Q6A A;  1VDR A;  3F8Y A;  4M7V A;  1RG7 A;  5CC9 A;  4KAK A;  5CCC A;  3FQZ A;  3SRU X;  5FDA A;  4P3Q A;  1PD9 A;  3TQ9 A;  4XT7 A;  2O7P A;  3DL5 A;  2ANO A;  4LEK X;  3DAU A;  3ZPC A;  2ANQ A;  2W9H A;  3NXR A;  4ELF A;  3SAI A;  4XT4 A;  4DFR A;  4KLX A;  2DHF A;  3E0B A;  1YHO A;  1DG8 A;  1DRE A;  3QLR A;  3IRN A;  3SR5 X;  3F0V X;  4QI9 A;  4ELE A;  3FL8 A;  1RX8 A;  4XT6 A;  2W3A A;  3F0X X;  2H2Q A;  3GI2 A;  3UM5 A;  1DR6 A;  3QFX A;  4OSG A;  2INQ A;  4HOF A;  1J3I A;  1RF7 A;  3DGA A;  1DF7 A;  1LY4 A;  3TD8 A;  3RO9 A;  3CL9 A;  3JTW A;  3IA5 A;  4H95 A;  4XT5 A;  4PSY A;  3OCH A;  3NZ6 X;  3KJR A;  5HVB A;  1DRA A;  4XEC X;  1M79 A;  4IXF X;  3SRR X;  1BZF A;  2W9S A;  2B3Z A;  3FRE X;  3Q1H A;  4NX7 A;  3S9U A;  1RA8 A;  2W3M A;  3KY8 A;  3EEM A;  3FYW X;  3M08 A;  5HI6 A;  1DLS A;  2BLA A;  3NXV A;  3NZA X;  1PD8 A;  3OAF A;  4DDR A;  4KY4 A;  5EAJ A;  3JW5 A;  4KM2 A;  5HSR A;  3L3R A;  4TU5 X;  3DG8 A;  2BLC A;  4P68 A;  3UM8 A;  4LAE X;  1JUV A;  1RD7 A;  3FRD X;  4KD7 A;  3FQC A;  1DYJ A;  4RGC A;  3JWK A;  3R33 A;  3FY9 X;  1DIS A;  2DRC A;  1U70 A;  3CD2 A;  3FL9 A;  2C2S A;  1E26 A;  4KJL A;  4XRB A;  3DAT A;  4EIL A;  4GH8 A;  3LG4 A;  2CIG A;  4X5G A;  3INV A;  4NX6 A;  3NU0 A;  1DG5 A;  3JWC A;  1MVT A;  1AOE A;  3K45 A;  3F0U X;  3QLX A;  3FQV A;  3GHW A;  1DR7 A;  4ELB A;  1DRF A;  1CD2 A;  2FZJ A;  1D1G A;  1DR5 A;  1J3K A;  3IX9 A;  1CZ3 A;  2KGK A;  2P4G A;  4KM0 A;  4ELG A;  2BLB A;  3SRW X;  1QZF A;  1DR2 A;  5HVE A;  1RX1 A;  3JWM A;  1RB2 A;  3CLB A;  5ECX A;  3KJS A;  4QJC A;  2LF1 A;  4PSS A;  1DHI A;  2ZZA A;  1KMS A;  2D5N A;  1RX7 A;  2CD2 A;  3NZB X;  4KEB A;  3N0H A;  5HT4 A;  5HQZ A;  4X5I A;  3ZPG A;  4M6J A;  3FQO A;  2W9G A;  3UM6 A;  3QLY A;  1HFP A;  3TQ8 A;  1M7A A;  3VCO A;  3NXO A;  3NXY A;  3S3V A;  1S3U A;  1AO8 A;  2OIP A;  4X5H A;  3FYV X;  3IRM A;  5HF2 X;  4PTH A;  3IA4 A;  4H97 A;  5E8Q A;  1S3Y A;  1M78 A;  1AI9 A;  1JOM A;  1OHJ A;  1DR3 A;  1DAJ A;  1DG7 A;  3M09 A;  3EIG A;  1IA4 A;  1DIU A;  2FZI A;  3S7A A;  4FGG A;  4QLE A;  5ECC A;  4X5J A;  4Q67 A;  3D80 A; 
#chains in the Genus database with same CATH topology
 3NTZ A;  1IA2 A;  1DDR A;  1S3V A;  3NXT A;  3D84 X;  1RA3 A;  3K74 A;  2HXV A;  2HQP A;  5U27 A;  4QLG A;  1DHJ A;  8DFR A;  1RA9 A;  3QLS A;  3EEJ A;  4QHV A;  4QJZ D;  1IA3 A;  3CSE A;  3GHV A;  4DP3 A;  2G6V A;  3EX8 A;  5HSU A;  4OR7 A;  1DLR A;  3FRA X;  3K47 A;  3QL0 A;  3DRC A;  3F8Z A;  4IXE D;  4LAG X;  1DYR A;  3EEL A;  4HA7 A;  5HUI A;  3GYF A;  5HPB A;  3F0Q X;  2HM9 A;  7DFR A;  1DRH A;  3SH2 A;  1RH3 A;  1SEJ A;  1DR4 A;  2W3V A;  4Q0E A;  1TDR A;  5DXV A;  5JA3 A;  5U26 A;  2L28 A;  1PDB A;  4KYA A;  4HA9 A;  1U72 A;  4G3M A;  2D0K A;  4HOG A;  4QLF A;  4FHB A;  4EJ1 A;  3SA2 A;  3SQY X;  3IRO A;  4FGH A;  1RB3 A;  5HQY A;  4ELH A;  4M7U A;  3NZC X;  4X5F A;  4KFJ A;  1DDS A;  3F0S X;  2AZN A;  3QYO A;  3NXX A;  1RC4 A;  3DL6 A;  4KL9 A;  1IA1 A;  3KFY A;  3F0B X;  4G95 A;  4KJK A;  3FRB X;  1VJ3 A;  3TQB A;  2XW7 A;  1DRB A;  1LUD A;  3QL3 A;  3I3R A;  1RX4 A;  4I13 A;  1ZDR A;  3QG2 A;  6DFR A;  1OHK A;  4CD2 A;  3FQ0 A;  1RA2 A;  3KGY A;  3QLW A;  2W3B A;  1DR1 A;  1RE7 A;  4Q0D A;  4KNE A;  3JWF A;  4XT8 A;  4PDJ A;  4KY8 A;  3NZ9 X;  1HFQ A;  4KJJ A;  3RG9 A;  1U71 A;  1RX9 A;  3JSU A;  1DYH A;  2QK8 A;  1RA1 A;  2BL9 A;  3SA1 A;  4PTJ A;  1HFR A;  2FZH A;  4XE6 X;  4I1N A;  3ROA A;  2GD9 A;  3QGT A;  3I8A X;  4EIG A;  4EIZ A;  3SRQ X;  4LAH X;  1RX3 A;  3SRS X;  3FS6 A;  2W3W A;  4KBN A;  2JYB A;  3QYL A;  4G8Z X;  1J3J A;  2ITH A;  3HBB A;  4IXG X;  5HT5 A;  5DFR A;  1DYI A;  3FY8 X;  4P3R A;  4H98 A;  2W9T A;  1JOL A;  5JG0 X;  4M2X A;  4P66 A;  3QLZ A;  1DHF A;  1LY3 A;  4PST A;  3FQF A;  1RX5 A;  3JVX A;  3F91 A;  1RX6 A;  3FRF X;  4M6K A;  1S3W A;  3JW3 A;  3NRR A;  3TQA A;  4DPD A;  3GHC A;  1KLK A;  4M6L A;  2OBC A;  3SGY A;  3K2H A;  4HOE A;  4DPH A;  4H96 A;  1KMV A;  3HJ3 A;  2C2T A;  1MVS A;  3NZD A;  1BOZ A;  3EEK A;  4ECK A;  5HF0 X;  3DFR A;  1RX2 A;  4Q6A A;  1VDR A;  3F8Y A;  4M7V A;  1RG7 A;  5CC9 A;  4KAK A;  5CCC A;  3FQZ A;  3SRU X;  5FDA A;  4P3Q A;  1PD9 A;  3TQ9 A;  4XT7 A;  2O7P A;  3DL5 A;  2ANO A;  4LEK X;  3DAU A;  3ZPC A;  2ANQ A;  2W9H A;  3NXR A;  4ELF A;  3SAI A;  4XT4 A;  4DFR A;  4KLX A;  2DHF A;  3E0B A;  1YHO A;  1DG8 A;  1DRE A;  3QLR A;  3IRN A;  3SR5 X;  3F0V X;  4QI9 A;  4ELE A;  3FL8 A;  1RX8 A;  4XT6 A;  2W3A A;  3F0X X;  2H2Q A;  3GI2 A;  3UM5 A;  1DR6 A;  3QFX A;  4OSG A;  2INQ A;  4HOF A;  1J3I A;  1RF7 A;  3DGA A;  1DF7 A;  1LY4 A;  3TD8 A;  3RO9 A;  3CL9 A;  3JTW A;  3IA5 A;  4H95 A;  4XT5 A;  4PSY A;  3OCH A;  3NZ6 X;  3KJR A;  5HVB A;  1DRA A;  4XEC X;  1M79 A;  4IXF X;  3SRR X;  1BZF A;  2W9S A;  2B3Z A;  3FRE X;  3Q1H A;  4NX7 A;  3S9U A;  1RA8 A;  2W3M A;  3KY8 A;  3EEM A;  3FYW X;  3M08 A;  5HI6 A;  1DLS A;  2BLA A;  3NXV A;  3NZA X;  1PD8 A;  3OAF A;  4DDR A;  4KY4 A;  5EAJ A;  3JW5 A;  4KM2 A;  5HSR A;  3L3R A;  4TU5 X;  3DG8 A;  2BLC A;  4P68 A;  3UM8 A;  4LAE X;  1JUV A;  1RD7 A;  3FRD X;  4KD7 A;  3FQC A;  1DYJ A;  4RGC A;  3JWK A;  3R33 A;  3FY9 X;  1DIS A;  2DRC A;  1U70 A;  3CD2 A;  3FL9 A;  2C2S A;  1E26 A;  4KJL A;  4XRB A;  3DAT A;  4EIL A;  4GH8 A;  3LG4 A;  2CIG A;  4X5G A;  3INV A;  4NX6 A;  3NU0 A;  1DG5 A;  3JWC A;  1MVT A;  1AOE A;  3K45 A;  3F0U X;  3QLX A;  3FQV A;  3GHW A;  1DR7 A;  4ELB A;  1DRF A;  1CD2 A;  2FZJ A;  1D1G A;  1DR5 A;  1J3K A;  3IX9 A;  1CZ3 A;  2KGK A;  2P4G A;  4KM0 A;  4ELG A;  2BLB A;  3SRW X;  1QZF A;  1DR2 A;  5HVE A;  1RX1 A;  3JWM A;  1RB2 A;  3CLB A;  5ECX A;  3KJS A;  4QJC A;  2LF1 A;  4PSS A;  1DHI A;  2ZZA A;  1KMS A;  2D5N A;  1RX7 A;  2CD2 A;  3NZB X;  4KEB A;  3N0H A;  5HT4 A;  5HQZ A;  4X5I A;  3ZPG A;  4M6J A;  3FQO A;  2W9G A;  3UM6 A;  3QLY A;  1HFP A;  3TQ8 A;  1M7A A;  3VCO A;  3NXO A;  3NXY A;  3S3V A;  1S3U A;  1AO8 A;  2OIP A;  4X5H A;  3FYV X;  3IRM A;  5HF2 X;  4PTH A;  3IA4 A;  4H97 A;  5E8Q A;  1S3Y A;  1M78 A;  1AI9 A;  1JOM A;  1OHJ A;  1DR3 A;  1DAJ A;  1DG7 A;  3M09 A;  3EIG A;  1IA4 A;  1DIU A;  2FZI A;  3S7A A;  4FGG A;  4QLE A;  5ECC A;  4X5J A;  4Q67 A;  3D80 A; 
#chains in the Genus database with same CATH homology
 3NTZ A;  1IA2 A;  1DDR A;  1S3V A;  3NXT A;  3D84 X;  1RA3 A;  3K74 A;  2HXV A;  2HQP A;  5U27 A;  4QLG A;  1DHJ A;  8DFR A;  1RA9 A;  3QLS A;  3EEJ A;  4QHV A;  4QJZ D;  1IA3 A;  3CSE A;  3GHV A;  4DP3 A;  2G6V A;  3EX8 A;  5HSU A;  4OR7 A;  1DLR A;  3FRA X;  3K47 A;  3QL0 A;  3DRC A;  3F8Z A;  4IXE D;  4LAG X;  1DYR A;  3EEL A;  4HA7 A;  5HUI A;  3GYF A;  5HPB A;  3F0Q X;  2HM9 A;  7DFR A;  1DRH A;  3SH2 A;  1RH3 A;  1SEJ A;  1DR4 A;  2W3V A;  4Q0E A;  1TDR A;  5DXV A;  5JA3 A;  5U26 A;  2L28 A;  1PDB A;  4KYA A;  4HA9 A;  1U72 A;  4G3M A;  2D0K A;  4HOG A;  4QLF A;  4FHB A;  4EJ1 A;  3SA2 A;  3SQY X;  3IRO A;  4FGH A;  1RB3 A;  5HQY A;  4ELH A;  4M7U A;  3NZC X;  4X5F A;  4KFJ A;  1DDS A;  3F0S X;  2AZN A;  3QYO A;  3NXX A;  1RC4 A;  3DL6 A;  4KL9 A;  1IA1 A;  3KFY A;  3F0B X;  4G95 A;  4KJK A;  3FRB X;  1VJ3 A;  3TQB A;  2XW7 A;  1DRB A;  1LUD A;  3QL3 A;  3I3R A;  1RX4 A;  4I13 A;  1ZDR A;  3QG2 A;  6DFR A;  1OHK A;  4CD2 A;  3FQ0 A;  1RA2 A;  3KGY A;  3QLW A;  2W3B A;  1DR1 A;  1RE7 A;  4Q0D A;  4KNE A;  3JWF A;  4XT8 A;  4PDJ A;  4KY8 A;  3NZ9 X;  1HFQ A;  4KJJ A;  3RG9 A;  1U71 A;  1RX9 A;  3JSU A;  1DYH A;  2QK8 A;  1RA1 A;  2BL9 A;  3SA1 A;  4PTJ A;  1HFR A;  2FZH A;  4XE6 X;  4I1N A;  3ROA A;  2GD9 A;  3QGT A;  3I8A X;  4EIG A;  4EIZ A;  3SRQ X;  4LAH X;  1RX3 A;  3SRS X;  3FS6 A;  2W3W A;  4KBN A;  2JYB A;  3QYL A;  4G8Z X;  1J3J A;  2ITH A;  3HBB A;  4IXG X;  5HT5 A;  5DFR A;  1DYI A;  3FY8 X;  4P3R A;  4H98 A;  2W9T A;  1JOL A;  5JG0 X;  4M2X A;  4P66 A;  3QLZ A;  1DHF A;  1LY3 A;  4PST A;  3FQF A;  1RX5 A;  3JVX A;  3F91 A;  1RX6 A;  3FRF X;  4M6K A;  1S3W A;  3JW3 A;  3NRR A;  3TQA A;  4DPD A;  3GHC A;  1KLK A;  4M6L A;  2OBC A;  3SGY A;  3K2H A;  4HOE A;  4DPH A;  4H96 A;  1KMV A;  3HJ3 A;  2C2T A;  1MVS A;  3NZD A;  1BOZ A;  3EEK A;  4ECK A;  5HF0 X;  3DFR A;  1RX2 A;  4Q6A A;  1VDR A;  3F8Y A;  4M7V A;  1RG7 A;  5CC9 A;  4KAK A;  5CCC A;  3FQZ A;  3SRU X;  5FDA A;  4P3Q A;  1PD9 A;  3TQ9 A;  4XT7 A;  2O7P A;  3DL5 A;  2ANO A;  4LEK X;  3DAU A;  3ZPC A;  2ANQ A;  2W9H A;  3NXR A;  4ELF A;  3SAI A;  4XT4 A;  4DFR A;  4KLX A;  2DHF A;  3E0B A;  1YHO A;  1DG8 A;  1DRE A;  3QLR A;  3IRN A;  3SR5 X;  3F0V X;  4QI9 A;  4ELE A;  3FL8 A;  1RX8 A;  4XT6 A;  2W3A A;  3F0X X;  2H2Q A;  3GI2 A;  3UM5 A;  1DR6 A;  3QFX A;  4OSG A;  2INQ A;  4HOF A;  1J3I A;  1RF7 A;  3DGA A;  1DF7 A;  1LY4 A;  3TD8 A;  3RO9 A;  3CL9 A;  3JTW A;  3IA5 A;  4H95 A;  4XT5 A;  4PSY A;  3OCH A;  3NZ6 X;  3KJR A;  5HVB A;  1DRA A;  4XEC X;  1M79 A;  4IXF X;  3SRR X;  1BZF A;  2W9S A;  2B3Z A;  3FRE X;  3Q1H A;  4NX7 A;  3S9U A;  1RA8 A;  2W3M A;  3KY8 A;  3EEM A;  3FYW X;  3M08 A;  5HI6 A;  1DLS A;  2BLA A;  3NXV A;  3NZA X;  1PD8 A;  3OAF A;  4DDR A;  4KY4 A;  5EAJ A;  3JW5 A;  4KM2 A;  5HSR A;  3L3R A;  4TU5 X;  3DG8 A;  2BLC A;  4P68 A;  3UM8 A;  4LAE X;  1JUV A;  1RD7 A;  3FRD X;  4KD7 A;  3FQC A;  1DYJ A;  4RGC A;  3JWK A;  3R33 A;  3FY9 X;  1DIS A;  2DRC A;  1U70 A;  3CD2 A;  3FL9 A;  2C2S A;  1E26 A;  4KJL A;  4XRB A;  3DAT A;  4EIL A;  4GH8 A;  3LG4 A;  2CIG A;  4X5G A;  3INV A;  4NX6 A;  3NU0 A;  1DG5 A;  3JWC A;  1MVT A;  1AOE A;  3K45 A;  3F0U X;  3QLX A;  3FQV A;  3GHW A;  1DR7 A;  4ELB A;  1DRF A;  1CD2 A;  2FZJ A;  1D1G A;  1DR5 A;  1J3K A;  3IX9 A;  1CZ3 A;  2KGK A;  2P4G A;  4KM0 A;  4ELG A;  2BLB A;  3SRW X;  1QZF A;  1DR2 A;  5HVE A;  1RX1 A;  3JWM A;  1RB2 A;  3CLB A;  5ECX A;  3KJS A;  4QJC A;  2LF1 A;  4PSS A;  1DHI A;  2ZZA A;  1KMS A;  2D5N A;  1RX7 A;  2CD2 A;  3NZB X;  4KEB A;  3N0H A;  5HT4 A;  5HQZ A;  4X5I A;  3ZPG A;  4M6J A;  3FQO A;  2W9G A;  3UM6 A;  3QLY A;  1HFP A;  3TQ8 A;  1M7A A;  3VCO A;  3NXO A;  3NXY A;  3S3V A;  1S3U A;  1AO8 A;  2OIP A;  4X5H A;  3FYV X;  3IRM A;  5HF2 X;  4PTH A;  3IA4 A;  4H97 A;  5E8Q A;  1S3Y A;  1M78 A;  1AI9 A;  1JOM A;  1OHJ A;  1DR3 A;  1DAJ A;  1DG7 A;  3M09 A;  3EIG A;  1IA4 A;  1DIU A;  2FZI A;  3S7A A;  4FGG A;  4QLE A;  5ECC A;  4X5J A;  4Q67 A;  3D80 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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