4PVGA

Crystal structure of protein tyrosine phosphatase shp2 catalytic domain complex with small molecular compound l88n79
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
275
structure length
264
Chain Sequence
FETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of protein tyrosine Shp2 catalytic domain complex with compound L88N79
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 11
total genus 82
structure length 264
sequence length 275
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2014-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 4pvgA00
5BX1A 3QCCA 1PH0A 1YGRA 4NWGA 3ZM2A 2IMGA 2CM2A 4JBCA 1C84A 2Q05A 4OHIA 5IBMA 4GE5A 3B7OA 3O3LA 2NZ6A 1LYVA 2F6YA 2OC3A 2GP0A 3M4UA 2F6WA 1NWLA 2CNHA 4PVGA 3ZV2A 1U24A 2CM3A 3ZM1A 4BPCA 5KA2A 5GTJA 2HY3A 2CNEA 2F70A 1G1FA 5K22A 1ONZA 1OHDA 1OETA 2CMBA 4GRYA 4QUMA 5KA8A 2Q47A 2H02A 5K9VA 2QDMA 3QCIA 4R0TA 4ZI4A 2NT7A 2BGDA 4RI4A 3ZMPA 2CNIA 1R6HA 3A5KA 2WGPA 4Z6BA 2ZMMA 2BIJA 2VEYA 2FJMA 1KAVA 5BZZA 3D42A 1PYNA 2A8BA 2PQ5A 1C86A 3BRHA 2BZLA 3EAXA 3PS5A 1A5YA 2QCJA 1JF7A 3EZZA 1YTWA 5HDEA 2GJTA 3MOZA 4J51A 1MKPA 3D1OA 1XM2A 1XXVA 2QDCA 1M3GA 1EENA 2CM7A 4OHHA 3CWEA 1NNYA 2F71A 2VEUA 1T4JA 2QBRA 1I9TA 1T49A 4JNBA 5LXQB 4DGPA 3O4TA 4JMJA 2B4PA 2H04A 2ZN7A 1LARA 4Y14A 4OHEA 2A3KA 3S4OA 4RH9A 1G7FA 1J4XA 2H4GA 5KADA 1XRIA 3QCDA 2AHSA 3F9BA 4GFVA 4R0SA 5K9WA 2B3OA 1Q6TA 5K23A 4NYHA 3GXHA 3AWGA 2I4GA 2Y96A 4OHDA 5K24A 1PTUA 3S3HA 5KA1A 4ICZA 2QBQA 4HJQA 5KA7A 1FPRA 2I3RA 3U96A 2C46A 3V0IA 5I6VA 5BZXA 2SHPA 4KI9A 1VHRA 3OLRA 3ZM0A 2QDPA 2G6ZA 2I6IA 4YR8B 3S3FA 4NNDA 4NX8A 3OMHA 4BJOA 2HVLA 2QCTA 4ZN5A 2CM8A 3I80A 2QBSA 3BLTA 2HC2A 2VEVA 4I8NA 4S0GA 3CM3A 1PTTA 1PXHA 5KA9A 5KACA 2HNPA 4JMKA 1OEMX 1PTVA 3F41A 3QKQA 2HNQA 1C88A 1G4US 2OZ5A 3ZM3A 2VEXA 4QBEA 2MBCA 1C87A 5KAAA 3RO1A 2PA5A 4GFUA 5M43A 3O4UA 3QCBA 2I75A 4WU3A 2I1YA 1YWFA 1G7GA 2NT2A 4RI5A 1Q6JA 5BUGA 1Q6SA 2VEWA 4QUNA 2AZRA 4Y2EA 2I5XA 4QBWA 1LQFA 3RGQA 1U26A 1X24A 3D44A 4GS0A 3QCKA 2B4OA 1XBOA 3QCMA 2P4DA 1FPZA 1C83A 3H2XA 3AWFA 3RGOA 1BZCA 2CNFA 1OESA 3BLUA 4HJPA 4YAAA 2CFVA 4D3QA 2J16B 2BV5A 1OEOX 1YFOA 3I7ZA 2FH7A 3QCFA 1T48A 2F6VA 4RKKA 4QAPA 1QZ0A 1RPMA 3I36A 3SMEA 3V0EA 3NMEA 1Q6NA 2B07A 2PT0A 1YPTA 1NO6A 1Q6PA 2HCMA 4OHLA 1GWZA 2G59A 3O4SA 5KA3A 1SUGA 2J16A 1PA9A 2FJNA 4D3RA 2ESBA 5MMZB 4ERCA 2NV5A 2CJZA 3V0JA 3QCEA 1I57A 2NLKA 2R0BA 4PYHA 4IKCA 2RF6A 2CMCA 1ZC0A 2YDUA 3LJ8A 5EHPA 1I9SA 1NZ7A 1WCHA 1OHCA 2CMAA 1G1HA 2JJDA 2P6XA 2B49A 1Q1MA 1D5RA 1XXPA 1YTNA 3EMUA 1YN9A 1AAXA 1L8GA 4KYRA 1Q6MA 4RHGA 1G4WR 3V0DA 3S4EA 1OEVA 1GFYA 1NWEA 2H03A 2OOQA 4H34A 1OEUA 4GWFA 3O5XA 4DGXA 2I3UA 3D1HA 1JLNA 1ZCKA 3V0FA 1QXKA 2F6ZA 3ZMQA 2Y2FA 3QCNA 2PBNA 2HC1A 3EU0A 1OHEA 2GWOA 2I6JA 3D1QA 5KA4A 4RDDA 2J17A 2F6FA 3QCLA 1ZCLA 1BZJA 1L8KA 2PSZA 2E0TA 2H4KA 2F6TA 1V3AA 3S3EA 3EB1A 1G1GA 4HRFA 3V0HA 3A5JA 4ZRTA 2DXPA 1NL9A 1PA1A 1RXDA 2PI7A 4GE6A 1C85A 2I4EA 4R30A 3BM8A 1YGUA 1ZZWA 3AWEA 3QCGA 3MMJA 4WTYA 4WOHA 4AZ1A 2I6OA 2F46A 5KABA 4MBBA 2H4VA 1PTYA 1ONYA 1WAXA 3GXGA 2B4SA 3F81A 3D9CA 2B4UA 1EEOA 3QCHA 2BGEA 4GRZA 5EHRA 3RZ2A 2HB1A 4KYQA 1U25A 1ECVA 2NTAA 4D3PA 5IBSA 5J8RA 2I6PA 4WU2A 4TVVA 4GE2A 1WRMA 2QBPA 3S3KA 2CNGA 4NWFA 1YTSA 2QEPA 2HXPA 4RH5A 2M3VA 3F99A 5KA0A 3F9AA 4H1OA 5K25A 3QCJA 3QKPA 3SR9A 2C7SA 2OUDA 4B04A 1BZHA 1FQ1A 3V0GA 3N0AA 1P15A 3MOWA 2I6MA 5AWXA 2I42A 4QAHA 1KAKA 1YZ4A 2I4HA
chains in the Genus database with same CATH superfamily
2GCBA 5BX1A 3QCCA 4ZIYA 1PH0A 1YGRA 4NWGA 3ZM2A 2IMGA 2CM2A 4JBCA 1C84A 2Q05A 3ZM5A 2Y68A 4OHIA 5IBMA 4CVLA 4GE5A 3B7OA 3O3LA 2NZ6A 1LYVA 2F6YA 2OC3A 2GP0A 3M4UA 3LK7A 2F6WA 1NWLA 2CNHA 4PVGA 3ZV2A 1U24A 2CM3A 3ZM1A 4BPCA 5KA2A 5GTJA 2HY3A 2CNEA 1P31A 2F70A 1G1FA 5K22A 1ONZA 1OHDA 1OETA 2CMBA 4GRYA 4QUMA 5KA8A 2Q47A 2H02A 2X5OA 5K9VA 2QDMA 3QCIA 4R0TA 4ZI4A 2NT7A 2BGDA 4QF5A 4RI4A 3ZMPA 2CNIA 1R6HA 3A5KA 2WGPA 4Z6BA 2ZMMA 2BIJA 2VEYA 2FJMA 1KAVA 5BZZA 3D42A 1PYNA 2A8BA 2PQ5A 1C86A 3BRHA 2BZLA 3EAXA 3PS5A 1A5YA 4CVMA 2AM2A 2QCJA 1JF7A 3EZZA 1YTWA 5HDEA 2GJTA 3MOZA 4J51A 1MKPA 3D1OA 2Y1OA 1XM2A 1XXVA 2QDCA 1M3GA 1EENA 2CM7A 4OHHA 3CWEA 1NNYA 2F71A 2VEUA 1T4JA 2QBRA 1I9TA 1T49A 4JNBA 5LXQB 4DGPA 3O4TA 2JFGA 4JMJA 2B4PA 2H04A 2ZN7A 1LARA 4Y14A 4OHEA 2A3KA 2GC6A 3S4OA 1P3DA 4RH9A 1G7FA 1J4XA 2H4GA 5KADA 1XRIA 3QCDA 2AHSA 3F9BA 4GFVA 4R0SA 5K9WA 2B3OA 1Q6TA 5K23A 4NYHA 3GXHA 3AWGA 2I4GA 2Y96A 4OHDA 5K24A 4BUBA 1PTUA 3S3HA 5KA1A 4ICZA 2QBQA 4HJQA 5KA7A 1FPRA 2I3RA 3U96A 2C46A 3V0IA 5I6VA 5BZXA 2SHPA 3UAGA 4KI9A 1VHRA 3OLRA 3ZM0A 1J6UA 2QDPA 2G6ZA 2I6IA 4YR8B 3S3FA 4NNDA 4NX8A 3OMHA 4BJOA 2HVLA 2QCTA 4ZN5A 2CM8A 3I80A 2VORA 2GC5A 2QBSA 3BLTA 2HC2A 2VEVA 4I8NA 4S0GA 3CM3A 1PTTA 1PXHA 5KA9A 5KACA 2HNPA 4JMKA 1OEMX 3N2AA 1PTVA 3F41A 3QKQA 2HNQA 1C88A 1G4US 2OZ5A 3ZM3A 2VEXA 4QBEA 2MBCA 1C87A 5KAAA 3RO1A 1E0DA 2PA5A 2UUPA 4GFUA 5M43A 3O4UA 3QCBA 2I75A 4WU3A 2I1YA 1YWFA 1G7GA 2NT2A 3QCZA 4RI5A 1Q6JA 5BUGA 1Q6SA 2VEWA 4QUNA 2AZRA 3MVNA 2VOSA 4Y2EA 2I5XA 4QBWA 1LQFA 3RGQA 1U26A 1X24A 3D44A 4GS0A 3QCKA 1E8CA 2B4OA 1XBOA 3QCMA 2P4DA 2XJAA 1JBVA 1FPZA 1C83A 3H2XA 2VTDA 3AWFA 3RGOA 1BZCA 2CNFA 1OESA 3BLUA 4HJPA 4YAAA 2CFVA 3NRSA 4C13A 4D3QA 2J16B 2BV5A 2F00A 2XPCA 1OEOX 1YFOA 3I7ZA 2FH7A 3QCFA 2GCAA 1W78A 1T48A 3PYZA 2F6VA 4RKKA 4QAPA 1QZ0A 1RPMA 3I36A 3SMEA 3V0EA 5A5FA 1FGSA 3NMEA 1Q6NA 2B07A 2PT0A 1YPTA 1NO6A 1Q6PA 2HCMA 4OHLA 1GWZA 2G59A 3O4SA 5KA3A 1SUGA 1EEHA 2J16A 1PA9A 2FJNA 4D3RA 2ESBA 5MMZB 4ERCA 2Y67A 2NV5A 2WJPA 2CJZA 2VTEA 1GQQA 3V0JA 3QCEA 1I57A 2NLKA 2R0BA 4PYHA 4IKCA 2RF6A 4HV4A 2CMCA 1ZC0A 2YDUA 3LJ8A 5EHPA 1I9SA 1NZ7A 1WCHA 1GQYA 1JBWA 1OHCA 2CMAA 4CVKA 1G1HA 3ZM6A 2JJDA 2P6XA 2B49A 1Q1MA 1D5RA 1XXPA 1YTNA 3EMUA 1YN9A 1AAXA 1L8GA 4KYRA 1Q6MA 4RHGA 1G4WR 3V0DA 3S4EA 1OEVA 1GFYA 1NWEA 2H03A 2OOQA 4H34A 5A5EA 1GG4A 1UAGA 1OEUA 4GWFA 3O5XA 4DGXA 2I3UA 4BUCA 3D1HA 1JLNA 1ZCKA 2AM1A 4UAGA 3V0FA 1QXKA 2F6ZA 3ZMQA 2UAGA 1O5ZA 2Y2FA 3QCNA 2PBNA 2HC1A 2UUOA 3EU0A 1OHEA 2GWOA 2I6JA 3D1QA 5KA4A 4RDDA 2J17A 2F6FA 3QCLA 1ZCLA 1BZJA 1L8KA 2PSZA 2E0TA 2H4KA 2F6TA 1V3AA 3S3EA 3EB1A 1G1GA 4HRFA 3V0HA 3A5JA 4ZRTA 2DXPA 1NL9A 1PA1A 1RXDA 2PI7A 4GE6A 3ZL8A 3HN7A 1C85A 4QDIA 2I4EA 4R30A 3BM8A 1YGUA 1ZZWA 3AWEA 2JFFA 3QCGA 3MMJA 4WTYA 2Y66A 2WTZA 4WOHA 4AZ1A 2I6OA 2F46A 4C12A 5KABA 4MBBA 1W7KA 1PTYA 1ONYA 2H4VA 1WAXA 3GXGA 2B4SA 3F81A 3D9CA 2B4UA 1EEOA 3QCHA 2BGEA 4GRZA 5EHRA 3RZ2A 2HB1A 4KYQA 1U25A 1ECVA 2NTAA 4D3PA 5IBSA 5J8RA 2I6PA 4WU2A 4TVVA 4GE2A 1WRMA 2QBPA 3S3KA 2CNGA 4NWFA 1YTSA 2QEPA 2HXPA 4RH5A 2M3VA 3F99A 5KA0A 3F9AA 4H1OA 5K25A 3QCJA 3QKPA 2JFHA 3SR9A 2C7SA 2OUDA 4B04A 1BZHA 1FQ1A 3V0GA 3N0AA 1P15A 3MOWA 2I6MA 5AWXA 2I42A 4QAHA 1KAKA 1YZ4A 2I4HA
chains in the Genus database with same CATH topology
5BX1A 3QCCA 1PH0A 1YGRA 4NWGA 3ZM2A 2IMGA 2CM2A 4JBCA 1C84A 2Q05A 4OHIA 5IBMA 4GE5A 3B7OA 3O3LA 2NZ6A 1LYVA 2F6YA 2OC3A 2GP0A 3M4UA 2F6WA 1NWLA 2CNHA 4PVGA 3ZV2A 1U24A 2CM3A 3ZM1A 4BPCA 5KA2A 5GTJA 2HY3A 2CNEA 2F70A 1G1FA 5K22A 1ONZA 1OHDA 1OETA 2CMBA 4GRYA 4QUMA 5KA8A 2Q47A 2H02A 5K9VA 2QDMA 3QCIA 4R0TA 4ZI4A 2NT7A 2BGDA 4RI4A 3ZMPA 2CNIA 1R6HA 3A5KA 2WGPA 4Z6BA 2ZMMA 2BIJA 2VEYA 2FJMA 1KAVA 5BZZA 3D42A 1PYNA 2A8BA 2PQ5A 1C86A 3BRHA 2BZLA 3EAXA 3PS5A 1A5YA 2QCJA 1JF7A 3EZZA 1YTWA 5HDEA 2GJTA 3MOZA 4J51A 1MKPA 3D1OA 1XM2A 1XXVA 2QDCA 1M3GA 1EENA 2CM7A 4OHHA 3CWEA 1NNYA 2F71A 2VEUA 1T4JA 2QBRA 1I9TA 1T49A 4JNBA 5LXQB 4DGPA 3O4TA 4JMJA 2B4PA 2H04A 2ZN7A 1LARA 4Y14A 4OHEA 2A3KA 3S4OA 4RH9A 1G7FA 1J4XA 2H4GA 5KADA 1XRIA 3QCDA 2AHSA 3F9BA 4GFVA 4R0SA 5K9WA 2B3OA 1Q6TA 5K23A 4NYHA 3GXHA 3AWGA 2I4GA 2Y96A 4OHDA 5K24A 1PTUA 3S3HA 5KA1A 4ICZA 2QBQA 4HJQA 5KA7A 1FPRA 2I3RA 3U96A 2C46A 3V0IA 5I6VA 5BZXA 2SHPA 4KI9A 1VHRA 3OLRA 3ZM0A 2QDPA 2G6ZA 2I6IA 4YR8B 3S3FA 4NNDA 4NX8A 3OMHA 4BJOA 2HVLA 2QCTA 4ZN5A 2CM8A 3I80A 2QBSA 3BLTA 2HC2A 2VEVA 4I8NA 4S0GA 3CM3A 1PTTA 1PXHA 5KA9A 5KACA 2HNPA 4JMKA 1OEMX 1PTVA 3F41A 3QKQA 2HNQA 1C88A 1G4US 2OZ5A 3ZM3A 2VEXA 4QBEA 2MBCA 1C87A 5KAAA 3RO1A 2PA5A 4GFUA 5M43A 3O4UA 3QCBA 2I75A 4WU3A 2I1YA 1YWFA 1G7GA 2NT2A 4RI5A 1Q6JA 5BUGA 1Q6SA 2VEWA 4QUNA 2AZRA 4Y2EA 2I5XA 4QBWA 1LQFA 3RGQA 1U26A 1X24A 3D44A 4GS0A 3QCKA 2B4OA 1XBOA 3QCMA 2P4DA 1FPZA 1C83A 3H2XA 3AWFA 3RGOA 1BZCA 2CNFA 1OESA 3BLUA 4HJPA 4YAAA 2CFVA 4D3QA 2J16B 2BV5A 1OEOX 1YFOA 3I7ZA 2FH7A 3QCFA 1T48A 2F6VA 4RKKA 4QAPA 1QZ0A 1RPMA 3I36A 3SMEA 3V0EA 3NMEA 1Q6NA 2B07A 2PT0A 1YPTA 1NO6A 1Q6PA 2HCMA 4OHLA 1GWZA 2G59A 3O4SA 5KA3A 1SUGA 2J16A 1PA9A 2FJNA 4D3RA 2ESBA 5MMZB 4ERCA 2NV5A 2CJZA 3V0JA 3QCEA 1I57A 2NLKA 2R0BA 4PYHA 4IKCA 2RF6A 2CMCA 1ZC0A 2YDUA 3LJ8A 5EHPA 1I9SA 1NZ7A 1WCHA 1OHCA 2CMAA 1G1HA 2JJDA 2P6XA 2B49A 1Q1MA 1D5RA 1XXPA 1YTNA 3EMUA 1YN9A 1AAXA 1L8GA 4KYRA 1Q6MA 4RHGA 1G4WR 3V0DA 3S4EA 1OEVA 1GFYA 1NWEA 2H03A 2OOQA 4H34A 1OEUA 4GWFA 3O5XA 4DGXA 2I3UA 3D1HA 1JLNA 1ZCKA 3V0FA 1QXKA 2F6ZA 3ZMQA 2Y2FA 3QCNA 2PBNA 2HC1A 3EU0A 1OHEA 2GWOA 2I6JA 3D1QA 5KA4A 4RDDA 2J17A 2F6FA 3QCLA 1ZCLA 1BZJA 1L8KA 2PSZA 2E0TA 2H4KA 2F6TA 1V3AA 3S3EA 3EB1A 1G1GA 4HRFA 3V0HA 3A5JA 4ZRTA 2DXPA 1NL9A 1PA1A 1RXDA 2PI7A 4GE6A 1C85A 2I4EA 4R30A 3BM8A 1YGUA 1ZZWA 3AWEA 3QCGA 3MMJA 4WTYA 4WOHA 4AZ1A 2I6OA 2F46A 5KABA 4MBBA 2H4VA 1PTYA 1ONYA 1WAXA 3GXGA 2B4SA 3F81A 3D9CA 2B4UA 1EEOA 3QCHA 2BGEA 4GRZA 5EHRA 3RZ2A 2HB1A 4KYQA 1U25A 1ECVA 2NTAA 4D3PA 5IBSA 5J8RA 2I6PA 4WU2A 4TVVA 4GE2A 1WRMA 2QBPA 3S3KA 2CNGA 4NWFA 1YTSA 2QEPA 2HXPA 4RH5A 2M3VA 3F99A 5KA0A 3F9AA 4H1OA 5K25A 3QCJA 3QKPA 3SR9A 2C7SA 2OUDA 4B04A 1BZHA 1FQ1A 3V0GA 3N0AA 1P15A 3MOWA 2I6MA 5AWXA 2I42A 4QAHA 1KAKA 1YZ4A 2I4HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5BX1 A;  3QCC A;  1PH0 A;  1YGR A;  4NWG A;  3ZM2 A;  2IMG A;  2CM2 A;  4JBC A;  1C84 A;  2Q05 A;  4OHI A;  5IBM A;  4GE5 A;  3B7O A;  3O3L A;  2NZ6 A;  1LYV A;  2F6Y A;  2OC3 A;  2GP0 A;  3M4U A;  2F6W A;  1NWL A;  2CNH A;  4PVG A;  3ZV2 A;  1U24 A;  2CM3 A;  3ZM1 A;  4BPC A;  5KA2 A;  5GTJ A;  2HY3 A;  2CNE A;  2F70 A;  1G1F A;  5K22 A;  1ONZ A;  1OHD A;  1OET A;  2CMB A;  4GRY A;  4QUM A;  5KA8 A;  2Q47 A;  2H02 A;  5K9V A;  2QDM A;  3QCI A;  4R0T A;  4ZI4 A;  2NT7 A;  2BGD A;  4RI4 A;  3ZMP A;  2CNI A;  1R6H A;  3A5K A;  2WGP A;  4Z6B A;  2ZMM A;  2BIJ A;  2VEY A;  2FJM A;  1KAV A;  5BZZ A;  3D42 A;  1PYN A;  2A8B A;  2PQ5 A;  1C86 A;  3BRH A;  2BZL A;  3EAX A;  3PS5 A;  1A5Y A;  2QCJ A;  1JF7 A;  3EZZ A;  1YTW A;  5HDE A;  2GJT A;  3MOZ A;  4J51 A;  1MKP A;  3D1O A;  1XM2 A;  1XXV A;  2QDC A;  1M3G A;  1EEN A;  2CM7 A;  4OHH A;  3CWE A;  1NNY A;  2F71 A;  2VEU A;  1T4J A;  2QBR A;  1I9T A;  1T49 A;  4JNB A;  5LXQ B;  4DGP A;  3O4T A;  4JMJ A;  2B4P A;  2H04 A;  2ZN7 A;  1LAR A;  4Y14 A;  4OHE A;  2A3K A;  3S4O A;  4RH9 A;  1G7F A;  1J4X A;  2H4G A;  5KAD A;  1XRI A;  3QCD A;  2AHS A;  3F9B A;  4GFV A;  4R0S A;  5K9W A;  2B3O A;  1Q6T A;  5K23 A;  4NYH A;  3GXH A;  3AWG A;  2I4G A;  2Y96 A;  4OHD A;  5K24 A;  1PTU A;  3S3H A;  5KA1 A;  4ICZ A;  2QBQ A;  4HJQ A;  5KA7 A;  1FPR A;  2I3R A;  3U96 A;  2C46 A;  3V0I A;  5I6V A;  5BZX A;  2SHP A;  4KI9 A;  1VHR A;  3OLR A;  3ZM0 A;  2QDP A;  2G6Z A;  2I6I A;  4YR8 B;  3S3F A;  4NND A;  4NX8 A;  3OMH A;  4BJO A;  2HVL A;  2QCT A;  4ZN5 A;  2CM8 A;  3I80 A;  2QBS A;  3BLT A;  2HC2 A;  2VEV A;  4I8N A;  4S0G A;  3CM3 A;  1PTT A;  1PXH A;  5KA9 A;  5KAC A;  2HNP A;  4JMK A;  1OEM X;  1PTV A;  3F41 A;  3QKQ A;  2HNQ A;  1C88 A;  1G4U S;  2OZ5 A;  3ZM3 A;  2VEX A;  4QBE A;  2MBC A;  1C87 A;  5KAA A;  3RO1 A;  2PA5 A;  4GFU A;  5M43 A;  3O4U A;  3QCB A;  2I75 A;  4WU3 A;  2I1Y A;  1YWF A;  1G7G A;  2NT2 A;  4RI5 A;  1Q6J A;  5BUG A;  1Q6S A;  2VEW A;  4QUN A;  2AZR A;  4Y2E A;  2I5X A;  4QBW A;  1LQF A;  3RGQ A;  1U26 A;  1X24 A;  3D44 A;  4GS0 A;  3QCK A;  2B4O A;  1XBO A;  3QCM A;  2P4D A;  1FPZ A;  1C83 A;  3H2X A;  3AWF A;  3RGO A;  1BZC A;  2CNF A;  1OES A;  3BLU A;  4HJP A;  4YAA A;  2CFV A;  4D3Q A;  2J16 B;  2BV5 A;  1OEO X;  1YFO A;  3I7Z A;  2FH7 A;  3QCF A;  1T48 A;  2F6V A;  4RKK A;  4QAP A;  1QZ0 A;  1RPM A;  3I36 A;  3SME A;  3V0E A;  3NME A;  1Q6N A;  2B07 A;  2PT0 A;  1YPT A;  1NO6 A;  1Q6P A;  2HCM A;  4OHL A;  1GWZ A;  2G59 A;  3O4S A;  5KA3 A;  1SUG A;  2J16 A;  1PA9 A;  2FJN A;  4D3R A;  2ESB A;  5MMZ B;  4ERC A;  2NV5 A;  2CJZ A;  3V0J A;  3QCE A;  1I57 A;  2NLK A;  2R0B A;  4PYH A;  4IKC A;  2RF6 A;  2CMC A;  1ZC0 A;  2YDU A;  3LJ8 A;  5EHP A;  1I9S A;  1NZ7 A;  1WCH A;  1OHC A;  2CMA A;  1G1H A;  2JJD A;  2P6X A;  2B49 A;  1Q1M A;  1D5R A;  1XXP A;  1YTN A;  3EMU A;  1YN9 A;  1AAX A;  1L8G A;  4KYR A;  1Q6M A;  4RHG A;  1G4W R;  3V0D A;  3S4E A;  1OEV A;  1GFY A;  1NWE A;  2H03 A;  2OOQ A;  4H34 A;  1OEU A;  4GWF A;  3O5X A;  4DGX A;  2I3U A;  3D1H A;  1JLN A;  1ZCK A;  3V0F A;  1QXK A;  2F6Z A;  3ZMQ A;  2Y2F A;  3QCN A;  2PBN A;  2HC1 A;  3EU0 A;  1OHE A;  2GWO A;  2I6J A;  3D1Q A;  5KA4 A;  4RDD A;  2J17 A;  2F6F A;  3QCL A;  1ZCL A;  1BZJ A;  1L8K A;  2PSZ A;  2E0T A;  2H4K A;  2F6T A;  1V3A A;  3S3E A;  3EB1 A;  1G1G A;  4HRF A;  3V0H A;  3A5J A;  4ZRT A;  2DXP A;  1NL9 A;  1PA1 A;  1RXD A;  2PI7 A;  4GE6 A;  1C85 A;  2I4E A;  4R30 A;  3BM8 A;  1YGU A;  1ZZW A;  3AWE A;  3QCG A;  3MMJ A;  4WTY A;  4WOH A;  4AZ1 A;  2I6O A;  2F46 A;  5KAB A;  4MBB A;  2H4V A;  1PTY A;  1ONY A;  1WAX A;  3GXG A;  2B4S A;  3F81 A;  3D9C A;  2B4U A;  1EEO A;  3QCH A;  2BGE A;  4GRZ A;  5EHR A;  3RZ2 A;  2HB1 A;  4KYQ A;  1U25 A;  1ECV A;  2NTA A;  4D3P A;  5IBS A;  5J8R A;  2I6P A;  4WU2 A;  4TVV A;  4GE2 A;  1WRM A;  2QBP A;  3S3K A;  2CNG A;  4NWF A;  1YTS A;  2QEP A;  2HXP A;  4RH5 A;  2M3V A;  3F99 A;  5KA0 A;  3F9A A;  4H1O A;  5K25 A;  3QCJ A;  3QKP A;  3SR9 A;  2C7S A;  2OUD A;  4B04 A;  1BZH A;  1FQ1 A;  3V0G A;  3N0A A;  1P15 A;  3MOW A;  2I6M A;  5AWX A;  2I42 A;  4QAH A;  1KAK A;  1YZ4 A;  2I4H A; 
#chains in the Genus database with same CATH topology
 2GCB A;  5BX1 A;  3QCC A;  4ZIY A;  1PH0 A;  1YGR A;  4NWG A;  3ZM2 A;  2IMG A;  2CM2 A;  4JBC A;  1C84 A;  2Q05 A;  3ZM5 A;  2Y68 A;  4OHI A;  5IBM A;  4CVL A;  4GE5 A;  3B7O A;  3O3L A;  2NZ6 A;  1LYV A;  2F6Y A;  2OC3 A;  2GP0 A;  3M4U A;  3LK7 A;  2F6W A;  1NWL A;  2CNH A;  4PVG A;  3ZV2 A;  1U24 A;  2CM3 A;  3ZM1 A;  4BPC A;  5KA2 A;  5GTJ A;  2HY3 A;  2CNE A;  1P31 A;  2F70 A;  1G1F A;  5K22 A;  1ONZ A;  1OHD A;  1OET A;  2CMB A;  4GRY A;  4QUM A;  5KA8 A;  2Q47 A;  2H02 A;  2X5O A;  5K9V A;  2QDM A;  3QCI A;  4R0T A;  4ZI4 A;  2NT7 A;  2BGD A;  4QF5 A;  4RI4 A;  3ZMP A;  2CNI A;  1R6H A;  3A5K A;  2WGP A;  4Z6B A;  2ZMM A;  2BIJ A;  2VEY A;  2FJM A;  1KAV A;  5BZZ A;  3D42 A;  1PYN A;  2A8B A;  2PQ5 A;  1C86 A;  3BRH A;  2BZL A;  3EAX A;  3PS5 A;  1A5Y A;  4CVM A;  2AM2 A;  2QCJ A;  1JF7 A;  3EZZ A;  1YTW A;  5HDE A;  2GJT A;  3MOZ A;  4J51 A;  1MKP A;  3D1O A;  2Y1O A;  1XM2 A;  1XXV A;  2QDC A;  1M3G A;  1EEN A;  2CM7 A;  4OHH A;  3CWE A;  1NNY A;  2F71 A;  2VEU A;  1T4J A;  2QBR A;  1I9T A;  1T49 A;  4JNB A;  5LXQ B;  4DGP A;  3O4T A;  2JFG A;  4JMJ A;  2B4P A;  2H04 A;  2ZN7 A;  1LAR A;  4Y14 A;  4OHE A;  2A3K A;  2GC6 A;  3S4O A;  1P3D A;  4RH9 A;  1G7F A;  1J4X A;  2H4G A;  5KAD A;  1XRI A;  3QCD A;  2AHS A;  3F9B A;  4GFV A;  4R0S A;  5K9W A;  2B3O A;  1Q6T A;  5K23 A;  4NYH A;  3GXH A;  3AWG A;  2I4G A;  2Y96 A;  4OHD A;  5K24 A;  4BUB A;  1PTU A;  3S3H A;  5KA1 A;  4ICZ A;  2QBQ A;  4HJQ A;  5KA7 A;  1FPR A;  2I3R A;  3U96 A;  2C46 A;  3V0I A;  5I6V A;  5BZX A;  2SHP A;  3UAG A;  4KI9 A;  1VHR A;  3OLR A;  3ZM0 A;  1J6U A;  2QDP A;  2G6Z A;  2I6I A;  4YR8 B;  3S3F A;  4NND A;  4NX8 A;  3OMH A;  4BJO A;  2HVL A;  2QCT A;  4ZN5 A;  2CM8 A;  3I80 A;  2VOR A;  2GC5 A;  2QBS A;  3BLT A;  2HC2 A;  2VEV A;  4I8N A;  4S0G A;  3CM3 A;  1PTT A;  1PXH A;  5KA9 A;  5KAC A;  2HNP A;  4JMK A;  1OEM X;  3N2A A;  1PTV A;  3F41 A;  3QKQ A;  2HNQ A;  1C88 A;  1G4U S;  2OZ5 A;  3ZM3 A;  2VEX A;  4QBE A;  2MBC A;  1C87 A;  5KAA A;  3RO1 A;  1E0D A;  2PA5 A;  2UUP A;  4GFU A;  5M43 A;  3O4U A;  3QCB A;  2I75 A;  4WU3 A;  2I1Y A;  1YWF A;  1G7G A;  2NT2 A;  3QCZ A;  4RI5 A;  1Q6J A;  5BUG A;  1Q6S A;  2VEW A;  4QUN A;  2AZR A;  3MVN A;  2VOS A;  4Y2E A;  2I5X A;  4QBW A;  1LQF A;  3RGQ A;  1U26 A;  1X24 A;  3D44 A;  4GS0 A;  3QCK A;  1E8C A;  2B4O A;  1XBO A;  3QCM A;  2P4D A;  2XJA A;  1JBV A;  1FPZ A;  1C83 A;  3H2X A;  2VTD A;  3AWF A;  3RGO A;  1BZC A;  2CNF A;  1OES A;  3BLU A;  4HJP A;  4YAA A;  2CFV A;  3NRS A;  4C13 A;  4D3Q A;  2J16 B;  2BV5 A;  2F00 A;  2XPC A;  1OEO X;  1YFO A;  3I7Z A;  2FH7 A;  3QCF A;  2GCA A;  1W78 A;  1T48 A;  3PYZ A;  2F6V A;  4RKK A;  4QAP A;  1QZ0 A;  1RPM A;  3I36 A;  3SME A;  3V0E A;  5A5F A;  1FGS A;  3NME A;  1Q6N A;  2B07 A;  2PT0 A;  1YPT A;  1NO6 A;  1Q6P A;  2HCM A;  4OHL A;  1GWZ A;  2G59 A;  3O4S A;  5KA3 A;  1SUG A;  1EEH A;  2J16 A;  1PA9 A;  2FJN A;  4D3R A;  2ESB A;  5MMZ B;  4ERC A;  2Y67 A;  2NV5 A;  2WJP A;  2CJZ A;  2VTE A;  1GQQ A;  3V0J A;  3QCE A;  1I57 A;  2NLK A;  2R0B A;  4PYH A;  4IKC A;  2RF6 A;  4HV4 A;  2CMC A;  1ZC0 A;  2YDU A;  3LJ8 A;  5EHP A;  1I9S A;  1NZ7 A;  1WCH A;  1GQY A;  1JBW A;  1OHC A;  2CMA A;  4CVK A;  1G1H A;  3ZM6 A;  2JJD A;  2P6X A;  2B49 A;  1Q1M A;  1D5R A;  1XXP A;  1YTN A;  3EMU A;  1YN9 A;  1AAX A;  1L8G A;  4KYR A;  1Q6M A;  4RHG A;  1G4W R;  3V0D A;  3S4E A;  1OEV A;  1GFY A;  1NWE A;  2H03 A;  2OOQ A;  4H34 A;  5A5E A;  1GG4 A;  1UAG A;  1OEU A;  4GWF A;  3O5X A;  4DGX A;  2I3U A;  4BUC A;  3D1H A;  1JLN A;  1ZCK A;  2AM1 A;  4UAG A;  3V0F A;  1QXK A;  2F6Z A;  3ZMQ A;  2UAG A;  1O5Z A;  2Y2F A;  3QCN A;  2PBN A;  2HC1 A;  2UUO A;  3EU0 A;  1OHE A;  2GWO A;  2I6J A;  3D1Q A;  5KA4 A;  4RDD A;  2J17 A;  2F6F A;  3QCL A;  1ZCL A;  1BZJ A;  1L8K A;  2PSZ A;  2E0T A;  2H4K A;  2F6T A;  1V3A A;  3S3E A;  3EB1 A;  1G1G A;  4HRF A;  3V0H A;  3A5J A;  4ZRT A;  2DXP A;  1NL9 A;  1PA1 A;  1RXD A;  2PI7 A;  4GE6 A;  3ZL8 A;  3HN7 A;  1C85 A;  4QDI A;  2I4E A;  4R30 A;  3BM8 A;  1YGU A;  1ZZW A;  3AWE A;  2JFF A;  3QCG A;  3MMJ A;  4WTY A;  2Y66 A;  2WTZ A;  4WOH A;  4AZ1 A;  2I6O A;  2F46 A;  4C12 A;  5KAB A;  4MBB A;  1W7K A;  1PTY A;  1ONY A;  2H4V A;  1WAX A;  3GXG A;  2B4S A;  3F81 A;  3D9C A;  2B4U A;  1EEO A;  3QCH A;  2BGE A;  4GRZ A;  5EHR A;  3RZ2 A;  2HB1 A;  4KYQ A;  1U25 A;  1ECV A;  2NTA A;  4D3P A;  5IBS A;  5J8R A;  2I6P A;  4WU2 A;  4TVV A;  4GE2 A;  1WRM A;  2QBP A;  3S3K A;  2CNG A;  4NWF A;  1YTS A;  2QEP A;  2HXP A;  4RH5 A;  2M3V A;  3F99 A;  5KA0 A;  3F9A A;  4H1O A;  5K25 A;  3QCJ A;  3QKP A;  2JFH A;  3SR9 A;  2C7S A;  2OUD A;  4B04 A;  1BZH A;  1FQ1 A;  3V0G A;  3N0A A;  1P15 A;  3MOW A;  2I6M A;  5AWX A;  2I42 A;  4QAH A;  1KAK A;  1YZ4 A;  2I4H A; 
#chains in the Genus database with same CATH homology
 5BX1 A;  3QCC A;  1PH0 A;  1YGR A;  4NWG A;  3ZM2 A;  2IMG A;  2CM2 A;  4JBC A;  1C84 A;  2Q05 A;  4OHI A;  5IBM A;  4GE5 A;  3B7O A;  3O3L A;  2NZ6 A;  1LYV A;  2F6Y A;  2OC3 A;  2GP0 A;  3M4U A;  2F6W A;  1NWL A;  2CNH A;  4PVG A;  3ZV2 A;  1U24 A;  2CM3 A;  3ZM1 A;  4BPC A;  5KA2 A;  5GTJ A;  2HY3 A;  2CNE A;  2F70 A;  1G1F A;  5K22 A;  1ONZ A;  1OHD A;  1OET A;  2CMB A;  4GRY A;  4QUM A;  5KA8 A;  2Q47 A;  2H02 A;  5K9V A;  2QDM A;  3QCI A;  4R0T A;  4ZI4 A;  2NT7 A;  2BGD A;  4RI4 A;  3ZMP A;  2CNI A;  1R6H A;  3A5K A;  2WGP A;  4Z6B A;  2ZMM A;  2BIJ A;  2VEY A;  2FJM A;  1KAV A;  5BZZ A;  3D42 A;  1PYN A;  2A8B A;  2PQ5 A;  1C86 A;  3BRH A;  2BZL A;  3EAX A;  3PS5 A;  1A5Y A;  2QCJ A;  1JF7 A;  3EZZ A;  1YTW A;  5HDE A;  2GJT A;  3MOZ A;  4J51 A;  1MKP A;  3D1O A;  1XM2 A;  1XXV A;  2QDC A;  1M3G A;  1EEN A;  2CM7 A;  4OHH A;  3CWE A;  1NNY A;  2F71 A;  2VEU A;  1T4J A;  2QBR A;  1I9T A;  1T49 A;  4JNB A;  5LXQ B;  4DGP A;  3O4T A;  4JMJ A;  2B4P A;  2H04 A;  2ZN7 A;  1LAR A;  4Y14 A;  4OHE A;  2A3K A;  3S4O A;  4RH9 A;  1G7F A;  1J4X A;  2H4G A;  5KAD A;  1XRI A;  3QCD A;  2AHS A;  3F9B A;  4GFV A;  4R0S A;  5K9W A;  2B3O A;  1Q6T A;  5K23 A;  4NYH A;  3GXH A;  3AWG A;  2I4G A;  2Y96 A;  4OHD A;  5K24 A;  1PTU A;  3S3H A;  5KA1 A;  4ICZ A;  2QBQ A;  4HJQ A;  5KA7 A;  1FPR A;  2I3R A;  3U96 A;  2C46 A;  3V0I A;  5I6V A;  5BZX A;  2SHP A;  4KI9 A;  1VHR A;  3OLR A;  3ZM0 A;  2QDP A;  2G6Z A;  2I6I A;  4YR8 B;  3S3F A;  4NND A;  4NX8 A;  3OMH A;  4BJO A;  2HVL A;  2QCT A;  4ZN5 A;  2CM8 A;  3I80 A;  2QBS A;  3BLT A;  2HC2 A;  2VEV A;  4I8N A;  4S0G A;  3CM3 A;  1PTT A;  1PXH A;  5KA9 A;  5KAC A;  2HNP A;  4JMK A;  1OEM X;  1PTV A;  3F41 A;  3QKQ A;  2HNQ A;  1C88 A;  1G4U S;  2OZ5 A;  3ZM3 A;  2VEX A;  4QBE A;  2MBC A;  1C87 A;  5KAA A;  3RO1 A;  2PA5 A;  4GFU A;  5M43 A;  3O4U A;  3QCB A;  2I75 A;  4WU3 A;  2I1Y A;  1YWF A;  1G7G A;  2NT2 A;  4RI5 A;  1Q6J A;  5BUG A;  1Q6S A;  2VEW A;  4QUN A;  2AZR A;  4Y2E A;  2I5X A;  4QBW A;  1LQF A;  3RGQ A;  1U26 A;  1X24 A;  3D44 A;  4GS0 A;  3QCK A;  2B4O A;  1XBO A;  3QCM A;  2P4D A;  1FPZ A;  1C83 A;  3H2X A;  3AWF A;  3RGO A;  1BZC A;  2CNF A;  1OES A;  3BLU A;  4HJP A;  4YAA A;  2CFV A;  4D3Q A;  2J16 B;  2BV5 A;  1OEO X;  1YFO A;  3I7Z A;  2FH7 A;  3QCF A;  1T48 A;  2F6V A;  4RKK A;  4QAP A;  1QZ0 A;  1RPM A;  3I36 A;  3SME A;  3V0E A;  3NME A;  1Q6N A;  2B07 A;  2PT0 A;  1YPT A;  1NO6 A;  1Q6P A;  2HCM A;  4OHL A;  1GWZ A;  2G59 A;  3O4S A;  5KA3 A;  1SUG A;  2J16 A;  1PA9 A;  2FJN A;  4D3R A;  2ESB A;  5MMZ B;  4ERC A;  2NV5 A;  2CJZ A;  3V0J A;  3QCE A;  1I57 A;  2NLK A;  2R0B A;  4PYH A;  4IKC A;  2RF6 A;  2CMC A;  1ZC0 A;  2YDU A;  3LJ8 A;  5EHP A;  1I9S A;  1NZ7 A;  1WCH A;  1OHC A;  2CMA A;  1G1H A;  2JJD A;  2P6X A;  2B49 A;  1Q1M A;  1D5R A;  1XXP A;  1YTN A;  3EMU A;  1YN9 A;  1AAX A;  1L8G A;  4KYR A;  1Q6M A;  4RHG A;  1G4W R;  3V0D A;  3S4E A;  1OEV A;  1GFY A;  1NWE A;  2H03 A;  2OOQ A;  4H34 A;  1OEU A;  4GWF A;  3O5X A;  4DGX A;  2I3U A;  3D1H A;  1JLN A;  1ZCK A;  3V0F A;  1QXK A;  2F6Z A;  3ZMQ A;  2Y2F A;  3QCN A;  2PBN A;  2HC1 A;  3EU0 A;  1OHE A;  2GWO A;  2I6J A;  3D1Q A;  5KA4 A;  4RDD A;  2J17 A;  2F6F A;  3QCL A;  1ZCL A;  1BZJ A;  1L8K A;  2PSZ A;  2E0T A;  2H4K A;  2F6T A;  1V3A A;  3S3E A;  3EB1 A;  1G1G A;  4HRF A;  3V0H A;  3A5J A;  4ZRT A;  2DXP A;  1NL9 A;  1PA1 A;  1RXD A;  2PI7 A;  4GE6 A;  1C85 A;  2I4E A;  4R30 A;  3BM8 A;  1YGU A;  1ZZW A;  3AWE A;  3QCG A;  3MMJ A;  4WTY A;  4WOH A;  4AZ1 A;  2I6O A;  2F46 A;  5KAB A;  4MBB A;  2H4V A;  1PTY A;  1ONY A;  1WAX A;  3GXG A;  2B4S A;  3F81 A;  3D9C A;  2B4U A;  1EEO A;  3QCH A;  2BGE A;  4GRZ A;  5EHR A;  3RZ2 A;  2HB1 A;  4KYQ A;  1U25 A;  1ECV A;  2NTA A;  4D3P A;  5IBS A;  5J8R A;  2I6P A;  4WU2 A;  4TVV A;  4GE2 A;  1WRM A;  2QBP A;  3S3K A;  2CNG A;  4NWF A;  1YTS A;  2QEP A;  2HXP A;  4RH5 A;  2M3V A;  3F99 A;  5KA0 A;  3F9A A;  4H1O A;  5K25 A;  3QCJ A;  3QKP A;  3SR9 A;  2C7S A;  2OUD A;  4B04 A;  1BZH A;  1FQ1 A;  3V0G A;  3N0A A;  1P15 A;  3MOW A;  2I6M A;  5AWX A;  2I42 A;  4QAH A;  1KAK A;  1YZ4 A;  2I4H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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