4Q3VA

Crystal structure of schistosoma mansoni arginase in complex with inhibitor bec
Total Genus 123
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
123
sequence length
346
structure length
337
Chain Sequence
b'PKLLYTSANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDGIQLTDCGDIIPVELNEAEDPQRFGMKWSRSFSLTTLRIAERVEELMKQSNKSTPLVIVGGDHSMATGTILGHAEAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVKELQDQIPWLDDFEGIKPCLNASNIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEAVIKEALLAVNPRLEKAIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKLSVVELAELNPLLGSQEDVLKTQSSAVHILRACLGHCRSGHLPFKVRNLTDQGIMSRAAHMQT'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Arginase
publication title Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis.
pubmed doi rcsb
source organism Schistosoma mansoni
molecule tags Hydrolase/hydrolase inhibitor
total genus 123
structure length 337
sequence length 346
chains with identical sequence B, C, D
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2014-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 4q3vA00
1P8RA 2EF4A 1ZPGA 3MFVA 3SL1A 1TBLA 4IE3A 1ZPEA 2EF5A 2PHOA 3LP4A 1TA1A 4GWCA 3NIOA 1T4RA 2PHAA 3THJA 1TBHA 3SL0A 3CEVA 4GSVA 1GQ7A 3RLAA 4IU5A 3E8ZA 2CEVA 4Q40A 3PZLA 4HXQA 4FCKA 3NIPA 4Q3PA 4MYFA 5RLAA 4Q42A 3SKKA 3SJTA 3LHLA 4Q3UA 2PLLA 1HQHA 4IXVA 5CEVA 3THHA 1R1OA 1WOHA 5HJAA 3TH7A 4Q3VA 4IE2A 1P8PA 1P8SA 1P8OA 4MYKA 3M1RA 4IXUA 4RHLA 1P8QA 4IU0A 4Q3RC 1HQXA 3MJLA 3DJ8A 1HQGA 3MFWA 4IU1A 4RHKA 4Q3SA 3E9BA 5HJ9A 1HQFA 4GSZA 4CEVA 2EIVA 1T4PA 4GWDA 3KV2A 4G3HA 3GN0A 1T4SA 3THEA 4IE1A 3NIQA 1T5GA 3TF3A 4FCIA 3F80A 1TBJA 4DZ4A 2RLAA 4Q41A 3MMRA 3E6KA 1P8MA 1RLAA 4ITYA 4RHQA 1T5FA 2AEBA 1GQ6A 4Q3QA 4RHJA 4RHMA 1T4TA 1CEVA 4HZEA 4MYLA 4RHIA 3GMZA 1WOIA 4GSMA 4IU4A 1D3VA 1WOGA 4Q3TA 2ZAVA 4MYNA 3E8QA 4I06A 1WVAA 1P8NA 4Q3RA 4MXRA 3LP7A 4HWWA 1XFKA 4RLAA 3E6VA 1WVBA 2A0MA 1HQ5A 1PQ3A
chains in the Genus database with same CATH superfamily
1P8RA 2EF4A 3F0RA 4CBYA 4ZUQA 1ZPGA 3MFVA 3SL1A 1TBLA 4IE3A 1ZPEA 2EF5A 2PHOA 3LP4A 1TA1A 3C0ZA 4GWCA 5EF8A 2VQVA 3NIOA 5G0HA 5G0JA 3SFHA 1T4RA 2PHAA 3THJA 5JI5A 4QA3A 1TBHA 3SL0A 3CEVA 4LY1A 5BWZA 5G12A 5THUA 4GSVA 4RN1A 1GQ7A 5EFGA 5G17A 3EW8A 1ZZ0A 1T69A 4QA4A 4BZ9A 3RLAA 2VQOA 5EEMA 4IU5A 1C3PA 2VQMA 2V5XA 3MZ7A 5DC8A 3E8ZA 4LXZA 2CEVA 4Q40A 3EWFA 3PZLA 4HXQA 4QA1A 3Q9EA 4FCKA 4ZUPA 5A2SA 5G13A 5FUEA 3NIPA 3Q9CA 5G3WA 5THSA 4Q3PA 4QA0A 4MYFA 5RLAA 4CBTA 5DC6A 1C3SA 5G0GA 4Q42A 5EENA 5G0IA 3SKKA 3LHLA 3SJTA 5D1CA 4Q3UA 1ZZ1A 5EF7A 2PLLA 5THVA 1HQHA 4IXVA 5CEVA 1W22A 2V5WA 1R1OA 1WOHA 3THHA 5HJAA 5G1CA 4ZUMA 3TH7A 4Q3VA 4IE2A 5G0XA 1P8PA 1P8SA 4BZ5A 3MZ6A 1P8OA 4MYKA 5EFKB 3M1RA 3MZ4A 4IXUA 4QA2A 3EZTA 4QA7A 5DC5A 4RHLA 1P8QA 4IU0A 4Q3RC 1HQXA 3MJLA 3F07A 3DJ8A 1HQGA 5ICNB 3MFWA 4IU1A 4RHKA 5EFJD 4Q3SA 3E9BA 5DC7A 3SFFA 5HJ9A 1HQFA 5EEFA 4BZ6A 4BKXB 1ZZ3A 5G11A 5EFBD 5FCWA 4GSZA 4CEVA 2EIVA 5EFNA 1T4PA 4GWDA 3KV2A 4G3HA 3GN0A 1T4SA 2VQQA 3THEA 3Q9BA 3C0YA 4IE1A 3NIQA 5EEIA 1T5GA 5IWGA 3TF3A 4FCIA 3F80A 5D1DA 1T64A 1TBJA 2RLAA 4BZ7A 4DZ4A 4Q41A 3MMRA 3E6KA 5EEKA 1P8MA 2VCGA 1RLAA 5EFHA 4ITYA 5G0YA 2GH6A 1VKGA 1T5FA 2AEBA 1GQ6A 4Q3QA 4RHQA 5G10A 4RHJA 4RN2A 3RQDA 4RHMA 1T4TA 4CQFA 1CEVA 3MAXA 4HZEA 4MYLA 4RHIA 3GMZA 3ZNRA 1WOIA 4GSMA 4IU4A 3F06A 1D3VA 5D1BA 1T67A 1WOGA 4Q3TA 5LI3A 4ZUOA 4A69A 3Q9FA 2ZAVA 5IX0A 3EZPA 4MYNA 4QA5A 4ZUNA 3E8QA 1C3RA 4I06A 1WVAA 1P8NA 4Q3RA 4BZ8A 4MXRA 4RN0A 2VQWG 5G1BA 3LP7A 4HWWA 1XFKA 4QA6A 3E6VA 3MZ3A 3MENA 4RLAA 4ZURA 1WVBA 2A0MA 1HQ5A 2VQJA 1PQ3A 3C10A 5THTA 3ZNSA 5G1AA
chains in the Genus database with same CATH topology
1P8RA 2EF4A 1ZPGA 3MFVA 3SL1A 1TBLA 4IE3A 1ZPEA 2EF5A 2PHOA 3LP4A 1TA1A 4GWCA 3NIOA 1T4RA 2PHAA 3THJA 1TBHA 3SL0A 3CEVA 4GSVA 1GQ7A 3RLAA 4IU5A 3E8ZA 2CEVA 4Q40A 3PZLA 4HXQA 4FCKA 3NIPA 4Q3PA 4MYFA 5RLAA 4Q42A 3SKKA 3SJTA 3LHLA 4Q3UA 2PLLA 1HQHA 4IXVA 5CEVA 3THHA 1R1OA 1WOHA 5HJAA 3TH7A 4Q3VA 4IE2A 1P8PA 1P8SA 1P8OA 4MYKA 3M1RA 4IXUA 4RHLA 1P8QA 4IU0A 4Q3RC 1HQXA 3MJLA 3DJ8A 1HQGA 3MFWA 4IU1A 4RHKA 4Q3SA 3E9BA 5HJ9A 1HQFA 4GSZA 4CEVA 2EIVA 1T4PA 4GWDA 3KV2A 4G3HA 3GN0A 1T4SA 3THEA 4IE1A 3NIQA 1T5GA 3TF3A 4FCIA 3F80A 1TBJA 4DZ4A 2RLAA 4Q41A 3MMRA 3E6KA 1P8MA 1RLAA 4ITYA 4RHQA 1T5FA 2AEBA 1GQ6A 4Q3QA 4RHJA 4RHMA 1T4TA 1CEVA 4HZEA 4MYLA 4RHIA 3GMZA 1WOIA 4GSMA 4IU4A 1D3VA 1WOGA 4Q3TA 2ZAVA 4MYNA 3E8QA 4I06A 1WVAA 1P8NA 4Q3RA 4MXRA 3LP7A 4HWWA 1XFKA 4RLAA 3E6VA 1WVBA 2A0MA 1HQ5A 1PQ3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1P8R A;  2EF4 A;  1ZPG A;  3MFV A;  3SL1 A;  1TBL A;  4IE3 A;  1ZPE A;  2EF5 A;  2PHO A;  3LP4 A;  1TA1 A;  4GWC A;  3NIO A;  1T4R A;  2PHA A;  3THJ A;  1TBH A;  3SL0 A;  3CEV A;  4GSV A;  1GQ7 A;  3RLA A;  4IU5 A;  3E8Z A;  2CEV A;  4Q40 A;  3PZL A;  4HXQ A;  4FCK A;  3NIP A;  4Q3P A;  4MYF A;  5RLA A;  4Q42 A;  3SKK A;  3SJT A;  3LHL A;  4Q3U A;  2PLL A;  1HQH A;  4IXV A;  5CEV A;  3THH A;  1R1O A;  1WOH A;  5HJA A;  3TH7 A;  4Q3V A;  4IE2 A;  1P8P A;  1P8S A;  1P8O A;  4MYK A;  3M1R A;  4IXU A;  4RHL A;  1P8Q A;  4IU0 A;  4Q3R C;  1HQX A;  3MJL A;  3DJ8 A;  1HQG A;  3MFW A;  4IU1 A;  4RHK A;  4Q3S A;  3E9B A;  5HJ9 A;  1HQF A;  4GSZ A;  4CEV A;  2EIV A;  1T4P A;  4GWD A;  3KV2 A;  4G3H A;  3GN0 A;  1T4S A;  3THE A;  4IE1 A;  3NIQ A;  1T5G A;  3TF3 A;  4FCI A;  3F80 A;  1TBJ A;  4DZ4 A;  2RLA A;  4Q41 A;  3MMR A;  3E6K A;  1P8M A;  1RLA A;  4ITY A;  4RHQ A;  1T5F A;  2AEB A;  1GQ6 A;  4Q3Q A;  4RHJ A;  4RHM A;  1T4T A;  1CEV A;  4HZE A;  4MYL A;  4RHI A;  3GMZ A;  1WOI A;  4GSM A;  4IU4 A;  1D3V A;  1WOG A;  4Q3T A;  2ZAV A;  4MYN A;  3E8Q A;  4I06 A;  1WVA A;  1P8N A;  4Q3R A;  4MXR A;  3LP7 A;  4HWW A;  1XFK A;  4RLA A;  3E6V A;  1WVB A;  2A0M A;  1HQ5 A;  1PQ3 A; 
#chains in the Genus database with same CATH topology
 1P8R A;  2EF4 A;  3F0R A;  4CBY A;  4ZUQ A;  1ZPG A;  3MFV A;  3SL1 A;  1TBL A;  4IE3 A;  1ZPE A;  2EF5 A;  2PHO A;  3LP4 A;  1TA1 A;  3C0Z A;  4GWC A;  5EF8 A;  2VQV A;  3NIO A;  5G0H A;  5G0J A;  3SFH A;  1T4R A;  2PHA A;  3THJ A;  5JI5 A;  4QA3 A;  1TBH A;  3SL0 A;  3CEV A;  4LY1 A;  5BWZ A;  5G12 A;  5THU A;  4GSV A;  4RN1 A;  1GQ7 A;  5EFG A;  5G17 A;  3EW8 A;  1ZZ0 A;  1T69 A;  4QA4 A;  4BZ9 A;  3RLA A;  2VQO A;  5EEM A;  4IU5 A;  1C3P A;  2VQM A;  2V5X A;  3MZ7 A;  5DC8 A;  3E8Z A;  4LXZ A;  2CEV A;  4Q40 A;  3EWF A;  3PZL A;  4HXQ A;  4QA1 A;  3Q9E A;  4FCK A;  4ZUP A;  5A2S A;  5G13 A;  5FUE A;  3NIP A;  3Q9C A;  5G3W A;  5THS A;  4Q3P A;  4QA0 A;  4MYF A;  5RLA A;  4CBT A;  5DC6 A;  1C3S A;  5G0G A;  4Q42 A;  5EEN A;  5G0I A;  3SKK A;  3LHL A;  3SJT A;  5D1C A;  4Q3U A;  1ZZ1 A;  5EF7 A;  2PLL A;  5THV A;  1HQH A;  4IXV A;  5CEV A;  1W22 A;  2V5W A;  1R1O A;  1WOH A;  3THH A;  5HJA A;  5G1C A;  4ZUM A;  3TH7 A;  4Q3V A;  4IE2 A;  5G0X A;  1P8P A;  1P8S A;  4BZ5 A;  3MZ6 A;  1P8O A;  4MYK A;  5EFK B;  3M1R A;  3MZ4 A;  4IXU A;  4QA2 A;  3EZT A;  4QA7 A;  5DC5 A;  4RHL A;  1P8Q A;  4IU0 A;  4Q3R C;  1HQX A;  3MJL A;  3F07 A;  3DJ8 A;  1HQG A;  5ICN B;  3MFW A;  4IU1 A;  4RHK A;  5EFJ D;  4Q3S A;  3E9B A;  5DC7 A;  3SFF A;  5HJ9 A;  1HQF A;  5EEF A;  4BZ6 A;  4BKX B;  1ZZ3 A;  5G11 A;  5EFB D;  5FCW A;  4GSZ A;  4CEV A;  2EIV A;  5EFN A;  1T4P A;  4GWD A;  3KV2 A;  4G3H A;  3GN0 A;  1T4S A;  2VQQ A;  3THE A;  3Q9B A;  3C0Y A;  4IE1 A;  3NIQ A;  5EEI A;  1T5G A;  5IWG A;  3TF3 A;  4FCI A;  3F80 A;  5D1D A;  1T64 A;  1TBJ A;  2RLA A;  4BZ7 A;  4DZ4 A;  4Q41 A;  3MMR A;  3E6K A;  5EEK A;  1P8M A;  2VCG A;  1RLA A;  5EFH A;  4ITY A;  5G0Y A;  2GH6 A;  1VKG A;  1T5F A;  2AEB A;  1GQ6 A;  4Q3Q A;  4RHQ A;  5G10 A;  4RHJ A;  4RN2 A;  3RQD A;  4RHM A;  1T4T A;  4CQF A;  1CEV A;  3MAX A;  4HZE A;  4MYL A;  4RHI A;  3GMZ A;  3ZNR A;  1WOI A;  4GSM A;  4IU4 A;  3F06 A;  1D3V A;  5D1B A;  1T67 A;  1WOG A;  4Q3T A;  5LI3 A;  4ZUO A;  4A69 A;  3Q9F A;  2ZAV A;  5IX0 A;  3EZP A;  4MYN A;  4QA5 A;  4ZUN A;  3E8Q A;  1C3R A;  4I06 A;  1WVA A;  1P8N A;  4Q3R A;  4BZ8 A;  4MXR A;  4RN0 A;  2VQW G;  5G1B A;  3LP7 A;  4HWW A;  1XFK A;  4QA6 A;  3E6V A;  3MZ3 A;  3MEN A;  4RLA A;  4ZUR A;  1WVB A;  2A0M A;  1HQ5 A;  2VQJ A;  1PQ3 A;  3C10 A;  5THT A;  3ZNS A;  5G1A A; 
#chains in the Genus database with same CATH homology
 1P8R A;  2EF4 A;  1ZPG A;  3MFV A;  3SL1 A;  1TBL A;  4IE3 A;  1ZPE A;  2EF5 A;  2PHO A;  3LP4 A;  1TA1 A;  4GWC A;  3NIO A;  1T4R A;  2PHA A;  3THJ A;  1TBH A;  3SL0 A;  3CEV A;  4GSV A;  1GQ7 A;  3RLA A;  4IU5 A;  3E8Z A;  2CEV A;  4Q40 A;  3PZL A;  4HXQ A;  4FCK A;  3NIP A;  4Q3P A;  4MYF A;  5RLA A;  4Q42 A;  3SKK A;  3SJT A;  3LHL A;  4Q3U A;  2PLL A;  1HQH A;  4IXV A;  5CEV A;  3THH A;  1R1O A;  1WOH A;  5HJA A;  3TH7 A;  4Q3V A;  4IE2 A;  1P8P A;  1P8S A;  1P8O A;  4MYK A;  3M1R A;  4IXU A;  4RHL A;  1P8Q A;  4IU0 A;  4Q3R C;  1HQX A;  3MJL A;  3DJ8 A;  1HQG A;  3MFW A;  4IU1 A;  4RHK A;  4Q3S A;  3E9B A;  5HJ9 A;  1HQF A;  4GSZ A;  4CEV A;  2EIV A;  1T4P A;  4GWD A;  3KV2 A;  4G3H A;  3GN0 A;  1T4S A;  3THE A;  4IE1 A;  3NIQ A;  1T5G A;  3TF3 A;  4FCI A;  3F80 A;  1TBJ A;  4DZ4 A;  2RLA A;  4Q41 A;  3MMR A;  3E6K A;  1P8M A;  1RLA A;  4ITY A;  4RHQ A;  1T5F A;  2AEB A;  1GQ6 A;  4Q3Q A;  4RHJ A;  4RHM A;  1T4T A;  1CEV A;  4HZE A;  4MYL A;  4RHI A;  3GMZ A;  1WOI A;  4GSM A;  4IU4 A;  1D3V A;  1WOG A;  4Q3T A;  2ZAV A;  4MYN A;  3E8Q A;  4I06 A;  1WVA A;  1P8N A;  4Q3R A;  4MXR A;  3LP7 A;  4HWW A;  1XFK A;  4RLA A;  3E6V A;  1WVB A;  2A0M A;  1HQ5 A;  1PQ3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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