4Q42A

Crystal structure of schistosoma mansoni arginase in complex with l-ornithine
Total Genus 129
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
129
sequence length
345
structure length
336
Chain Sequence
b'KLLYTSANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDGIQLTDCGDIIPVELNEAEDPQRFGMKWSRSFSLTTLRIAERVEELMKQSNKSTPLVIVGGDHSMATGTILGHAEAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVKELQDQIPWLDDFEGIKPCLNASNIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEAVIKEALLAVNPRLEKAIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKLSVVELAELNPLLGSQEDVLKTQSSAVHILRACLGHCRSGHLPFKVRNLTDQGIMSRAAHMQTA'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Arginase
publication title Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis.
pubmed doi rcsb
source organism Schistosoma mansoni
molecule tags Hydrolase
total genus 129
structure length 336
sequence length 345
chains with identical sequence B, C, D
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2014-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 4q42A00
2A0MA 4Q3SA 4GWCA 4RHKA 5HJ9A 3E9BA 3NIPA 2AEBA 3E6VA 1T4PA 4DZ4A 3MFVA 1PQ3A 1HQXA 1P8SA 3CEVA 4Q3UA 3NIQA 3PZLA 3M1RA 1T5FA 1HQHA 1WVBA 3NIOA 4RHJA 3TH7A 5CEVA 2RLAA 2EIVA 1P8NA 3E8QA 1D3VA 4IU1A 3THEA 1WOGA 4Q3RC 4HXQA 4RHIA 5RLAA 4FCIA 4RHQA 4Q3VA 4IXVA 4IU4A 4RHLA 3LP7A 2CEVA 3TF3A 1WVAA 1TBJA 4Q3QA 1XFKA 1CEVA 1P8OA 4IE3A 1WOHA 3E8ZA 2EF4A 4I06A 3KV2A 4FCKA 4ITYA 4MYKA 1R1OA 2PHAA 2PLLA 1TBLA 4GSZA 3E6KA 3DJ8A 3SL0A 1HQ5A 4IE2A 4GWDA 3SKKA 3LHLA 4GSMA 4Q3PA 3RLAA 1P8PA 3GN0A 3SL1A 4HZEA 1P8RA 1HQFA 3GMZA 1TA1A 1GQ7A 4Q42A 4MYFA 1T5GA 4Q41A 1TBHA 4Q40A 4G3HA 1T4SA 2ZAVA 1GQ6A 4IU5A 3MJLA 4GSVA 3F80A 4MXRA 4Q3TA 3MFWA 3THHA 1T4TA 1WOIA 1RLAA 4RHMA 3LP4A 4IXUA 5HJAA 1ZPEA 2EF5A 4HWWA 1P8QA 3MMRA 1HQGA 1T4RA 4RLAA 4CEVA 2PHOA 4MYLA 4MYNA 1P8MA 3SJTA 4IE1A 3THJA 4Q3RA 4IU0A 1ZPGA
chains in the Genus database with same CATH superfamily
2A0MA 4Q3SA 4GWCA 2VQVA 3MZ3A 4RHKA 5EF7A 4CBYA 5D1BA 5ICNB 5THSA 5EF8A 1T69A 5HJ9A 3E9BA 3NIPA 5DC7A 2AEBA 5G1CA 3E6VA 1T4PA 4DZ4A 3MFVA 1PQ3A 2VCGA 1HQXA 1P8SA 4BZ6A 5EEIA 3CEVA 4Q3UA 3NIQA 3PZLA 3M1RA 5THTA 3MENA 1T5FA 1HQHA 1WVBA 3NIOA 4RHJA 3TH7A 5THVA 1C3RA 5IWGA 5CEVA 2RLAA 2EIVA 1P8NA 3E8QA 4QA5A 3MZ4A 1D3VA 4IU1A 4LY1A 3THEA 5EFHA 1WOGA 5G10A 1T67A 1C3PA 3MZ6A 1T64A 4HXQA 4Q3RC 4RHIA 4FCIA 5FUEA 5RLAA 4RHQA 5THUA 4CQFA 4Q3VA 2VQOA 4IXVA 4IU4A 4RHLA 3LP7A 2CEVA 5IX0A 1W22A 5BWZA 3TF3A 4ZUOA 1WVAA 1TBJA 4Q3QA 1XFKA 2VQQA 3RQDA 1CEVA 5EFGA 1P8OA 5G1BA 3F07A 4RN2A 4RN1A 5DC6A 4IE3A 4QA3A 5G0XA 2VQJA 5G17A 1WOHA 3Q9FA 4BKXB 4RN0A 3E8ZA 5EFJD 3SFFA 4BZ7A 2EF4A 4I06A 3KV2A 4FCKA 3Q9CA 4ITYA 4MYKA 5EFBD 1R1OA 2PHAA 3C0ZA 3Q9BA 1C3SA 2PLLA 1TBLA 4GSZA 5EEKA 3E6KA 3DJ8A 3SL0A 1HQ5A 3EZTA 4IE2A 4GWDA 5D1DA 3SKKA 3LHLA 3ZNRA 4GSMA 4Q3PA 3RLAA 1ZZ0A 4ZUPA 5LI3A 1P8PA 2VQMA 3GN0A 3MAXA 3SL1A 5EEMA 4BZ9A 4QA6A 5G0GA 4HZEA 1P8RA 1HQFA 2V5WA 3GMZA 5EEFA 1TA1A 1GQ7A 4Q42A 4MYFA 1T5GA 4Q41A 1TBHA 5A2SA 4Q40A 4G3HA 1T4SA 5DC5A 2ZAVA 1GQ6A 4IU5A 3MJLA 3EWFA 5G0YA 3F06A 4QA1A 4GSVA 4QA4A 3F80A 3MZ7A 4MXRA 5G1AA 1ZZ3A 4Q3TA 4ZUMA 3MFWA 3THHA 1T4TA 5G0IA 1WOIA 5G12A 5DC8A 1RLAA 4QA7A 3LP4A 4IXUA 4RHMA 4ZUNA 4BZ8A 4QA2A 5HJAA 5EENA 5G0HA 2V5XA 3EZPA 5G3WA 1ZPEA 2EF5A 4HWWA 4ZURA 3Q9EA 4A69A 1ZZ1A 4CBTA 3F0RA 1P8QA 3C0YA 3C10A 3MMRA 4LXZA 5G13A 5G0JA 4ZUQA 1HQGA 1T4RA 4RLAA 4BZ5A 2PHOA 4MYLA 4CEVA 5JI5A 4QA0A 4MYNA 5FCWA 1P8MA 3SFHA 5D1CA 3SJTA 4IE1A 2GH6A 5EFNA 3THJA 4Q3RA 3ZNSA 4IU0A 3EW8A 5EFKB 5G11A 1VKGA 2VQWG 1ZPGA
chains in the Genus database with same CATH topology
2A0MA 4Q3SA 4GWCA 4RHKA 5HJ9A 3E9BA 3NIPA 2AEBA 3E6VA 1T4PA 4DZ4A 3MFVA 1PQ3A 1HQXA 1P8SA 3CEVA 4Q3UA 3NIQA 3PZLA 3M1RA 1T5FA 1HQHA 1WVBA 3NIOA 4RHJA 3TH7A 5CEVA 2RLAA 2EIVA 1P8NA 3E8QA 1D3VA 4IU1A 3THEA 1WOGA 4Q3RC 4HXQA 4RHIA 5RLAA 4FCIA 4RHQA 4Q3VA 4IXVA 4IU4A 4RHLA 3LP7A 2CEVA 3TF3A 1WVAA 1TBJA 4Q3QA 1XFKA 1CEVA 1P8OA 4IE3A 1WOHA 3E8ZA 2EF4A 4I06A 3KV2A 4FCKA 4ITYA 4MYKA 1R1OA 2PHAA 2PLLA 1TBLA 4GSZA 3E6KA 3DJ8A 3SL0A 1HQ5A 4IE2A 4GWDA 3SKKA 3LHLA 4GSMA 4Q3PA 3RLAA 1P8PA 3GN0A 3SL1A 4HZEA 1P8RA 1HQFA 3GMZA 1TA1A 1GQ7A 4Q42A 4MYFA 1T5GA 4Q41A 1TBHA 4Q40A 4G3HA 1T4SA 2ZAVA 1GQ6A 4IU5A 3MJLA 4GSVA 3F80A 4MXRA 4Q3TA 3MFWA 3THHA 1T4TA 1WOIA 1RLAA 4RHMA 3LP4A 4IXUA 5HJAA 1ZPEA 2EF5A 4HWWA 1P8QA 3MMRA 1HQGA 1T4RA 4RLAA 4CEVA 2PHOA 4MYLA 4MYNA 1P8MA 3SJTA 4IE1A 3THJA 4Q3RA 4IU0A 1ZPGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A0M A;  4Q3S A;  4GWC A;  4RHK A;  5HJ9 A;  3E9B A;  3NIP A;  2AEB A;  3E6V A;  1T4P A;  4DZ4 A;  3MFV A;  1PQ3 A;  1HQX A;  1P8S A;  3CEV A;  4Q3U A;  3NIQ A;  3PZL A;  3M1R A;  1T5F A;  1HQH A;  1WVB A;  3NIO A;  4RHJ A;  3TH7 A;  5CEV A;  2RLA A;  2EIV A;  1P8N A;  3E8Q A;  1D3V A;  4IU1 A;  3THE A;  1WOG A;  4Q3R C;  4HXQ A;  4RHI A;  5RLA A;  4FCI A;  4RHQ A;  4Q3V A;  4IXV A;  4IU4 A;  4RHL A;  3LP7 A;  2CEV A;  3TF3 A;  1WVA A;  1TBJ A;  4Q3Q A;  1XFK A;  1CEV A;  1P8O A;  4IE3 A;  1WOH A;  3E8Z A;  2EF4 A;  4I06 A;  3KV2 A;  4FCK A;  4ITY A;  4MYK A;  1R1O A;  2PHA A;  2PLL A;  1TBL A;  4GSZ A;  3E6K A;  3DJ8 A;  3SL0 A;  1HQ5 A;  4IE2 A;  4GWD A;  3SKK A;  3LHL A;  4GSM A;  4Q3P A;  3RLA A;  1P8P A;  3GN0 A;  3SL1 A;  4HZE A;  1P8R A;  1HQF A;  3GMZ A;  1TA1 A;  1GQ7 A;  4Q42 A;  4MYF A;  1T5G A;  4Q41 A;  1TBH A;  4Q40 A;  4G3H A;  1T4S A;  2ZAV A;  1GQ6 A;  4IU5 A;  3MJL A;  4GSV A;  3F80 A;  4MXR A;  4Q3T A;  3MFW A;  3THH A;  1T4T A;  1WOI A;  1RLA A;  4RHM A;  3LP4 A;  4IXU A;  5HJA A;  1ZPE A;  2EF5 A;  4HWW A;  1P8Q A;  3MMR A;  1HQG A;  1T4R A;  4RLA A;  4CEV A;  2PHO A;  4MYL A;  4MYN A;  1P8M A;  3SJT A;  4IE1 A;  3THJ A;  4Q3R A;  4IU0 A;  1ZPG A; 
#chains in the Genus database with same CATH topology
 2A0M A;  4Q3S A;  4GWC A;  2VQV A;  3MZ3 A;  4RHK A;  5EF7 A;  4CBY A;  5D1B A;  5ICN B;  5THS A;  5EF8 A;  1T69 A;  5HJ9 A;  3E9B A;  3NIP A;  5DC7 A;  2AEB A;  5G1C A;  3E6V A;  1T4P A;  4DZ4 A;  3MFV A;  1PQ3 A;  2VCG A;  1HQX A;  1P8S A;  4BZ6 A;  5EEI A;  3CEV A;  4Q3U A;  3NIQ A;  3PZL A;  3M1R A;  5THT A;  3MEN A;  1T5F A;  1HQH A;  1WVB A;  3NIO A;  4RHJ A;  3TH7 A;  5THV A;  1C3R A;  5IWG A;  5CEV A;  2RLA A;  2EIV A;  1P8N A;  3E8Q A;  4QA5 A;  3MZ4 A;  1D3V A;  4IU1 A;  4LY1 A;  3THE A;  5EFH A;  1WOG A;  5G10 A;  1T67 A;  1C3P A;  3MZ6 A;  1T64 A;  4HXQ A;  4Q3R C;  4RHI A;  4FCI A;  5FUE A;  5RLA A;  4RHQ A;  5THU A;  4CQF A;  4Q3V A;  2VQO A;  4IXV A;  4IU4 A;  4RHL A;  3LP7 A;  2CEV A;  5IX0 A;  1W22 A;  5BWZ A;  3TF3 A;  4ZUO A;  1WVA A;  1TBJ A;  4Q3Q A;  1XFK A;  2VQQ A;  3RQD A;  1CEV A;  5EFG A;  1P8O A;  5G1B A;  3F07 A;  4RN2 A;  4RN1 A;  5DC6 A;  4IE3 A;  4QA3 A;  5G0X A;  2VQJ A;  5G17 A;  1WOH A;  3Q9F A;  4BKX B;  4RN0 A;  3E8Z A;  5EFJ D;  3SFF A;  4BZ7 A;  2EF4 A;  4I06 A;  3KV2 A;  4FCK A;  3Q9C A;  4ITY A;  4MYK A;  5EFB D;  1R1O A;  2PHA A;  3C0Z A;  3Q9B A;  1C3S A;  2PLL A;  1TBL A;  4GSZ A;  5EEK A;  3E6K A;  3DJ8 A;  3SL0 A;  1HQ5 A;  3EZT A;  4IE2 A;  4GWD A;  5D1D A;  3SKK A;  3LHL A;  3ZNR A;  4GSM A;  4Q3P A;  3RLA A;  1ZZ0 A;  4ZUP A;  5LI3 A;  1P8P A;  2VQM A;  3GN0 A;  3MAX A;  3SL1 A;  5EEM A;  4BZ9 A;  4QA6 A;  5G0G A;  4HZE A;  1P8R A;  1HQF A;  2V5W A;  3GMZ A;  5EEF A;  1TA1 A;  1GQ7 A;  4Q42 A;  4MYF A;  1T5G A;  4Q41 A;  1TBH A;  5A2S A;  4Q40 A;  4G3H A;  1T4S A;  5DC5 A;  2ZAV A;  1GQ6 A;  4IU5 A;  3MJL A;  3EWF A;  5G0Y A;  3F06 A;  4QA1 A;  4GSV A;  4QA4 A;  3F80 A;  3MZ7 A;  4MXR A;  5G1A A;  1ZZ3 A;  4Q3T A;  4ZUM A;  3MFW A;  3THH A;  1T4T A;  5G0I A;  1WOI A;  5G12 A;  5DC8 A;  1RLA A;  4QA7 A;  3LP4 A;  4IXU A;  4RHM A;  4ZUN A;  4BZ8 A;  4QA2 A;  5HJA A;  5EEN A;  5G0H A;  2V5X A;  3EZP A;  5G3W A;  1ZPE A;  2EF5 A;  4HWW A;  4ZUR A;  3Q9E A;  4A69 A;  1ZZ1 A;  4CBT A;  3F0R A;  1P8Q A;  3C0Y A;  3C10 A;  3MMR A;  4LXZ A;  5G13 A;  5G0J A;  4ZUQ A;  1HQG A;  1T4R A;  4RLA A;  4BZ5 A;  2PHO A;  4MYL A;  4CEV A;  5JI5 A;  4QA0 A;  4MYN A;  5FCW A;  1P8M A;  3SFH A;  5D1C A;  3SJT A;  4IE1 A;  2GH6 A;  5EFN A;  3THJ A;  4Q3R A;  3ZNS A;  4IU0 A;  3EW8 A;  5EFK B;  5G11 A;  1VKG A;  2VQW G;  1ZPG A; 
#chains in the Genus database with same CATH homology
 2A0M A;  4Q3S A;  4GWC A;  4RHK A;  5HJ9 A;  3E9B A;  3NIP A;  2AEB A;  3E6V A;  1T4P A;  4DZ4 A;  3MFV A;  1PQ3 A;  1HQX A;  1P8S A;  3CEV A;  4Q3U A;  3NIQ A;  3PZL A;  3M1R A;  1T5F A;  1HQH A;  1WVB A;  3NIO A;  4RHJ A;  3TH7 A;  5CEV A;  2RLA A;  2EIV A;  1P8N A;  3E8Q A;  1D3V A;  4IU1 A;  3THE A;  1WOG A;  4Q3R C;  4HXQ A;  4RHI A;  5RLA A;  4FCI A;  4RHQ A;  4Q3V A;  4IXV A;  4IU4 A;  4RHL A;  3LP7 A;  2CEV A;  3TF3 A;  1WVA A;  1TBJ A;  4Q3Q A;  1XFK A;  1CEV A;  1P8O A;  4IE3 A;  1WOH A;  3E8Z A;  2EF4 A;  4I06 A;  3KV2 A;  4FCK A;  4ITY A;  4MYK A;  1R1O A;  2PHA A;  2PLL A;  1TBL A;  4GSZ A;  3E6K A;  3DJ8 A;  3SL0 A;  1HQ5 A;  4IE2 A;  4GWD A;  3SKK A;  3LHL A;  4GSM A;  4Q3P A;  3RLA A;  1P8P A;  3GN0 A;  3SL1 A;  4HZE A;  1P8R A;  1HQF A;  3GMZ A;  1TA1 A;  1GQ7 A;  4Q42 A;  4MYF A;  1T5G A;  4Q41 A;  1TBH A;  4Q40 A;  4G3H A;  1T4S A;  2ZAV A;  1GQ6 A;  4IU5 A;  3MJL A;  4GSV A;  3F80 A;  4MXR A;  4Q3T A;  3MFW A;  3THH A;  1T4T A;  1WOI A;  1RLA A;  4RHM A;  3LP4 A;  4IXU A;  5HJA A;  1ZPE A;  2EF5 A;  4HWW A;  1P8Q A;  3MMR A;  1HQG A;  1T4R A;  4RLA A;  4CEV A;  2PHO A;  4MYL A;  4MYN A;  1P8M A;  3SJT A;  4IE1 A;  3THJ A;  4Q3R A;  4IU0 A;  1ZPG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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